deep-principle/science_biology huggingface dataset:
GWAS Phenotype: Multi-trait sex score
Genes in Locus: APOC1, APOC2, APOC4, APOC4-APOC2, APOE, BCAM, BCL3, BLOC1S3, CBLC, CEACAM16, CEACAM19, CEACAM20, CKM, CLASRP, CLPTM1, ENSG00000267173, ERCC2, EXOC3L2, GEMIN7, IGSF23, KLC3, MARK4, NECTIN2, NKPD1, PPP1R13L, PPP1R37, PVR, RELB, TOMM40, TRAPPC6A, ZNF180, ZNF229, ZNF285, ZNF296
Most likely causal gene: APOE
GWAS Phenotype: Metabolite levels (glutarylcarnitine (C5); glutarylcarnitine (C5-DC); C5-DC carnitine; C5_DC_carnitine)
Genes in Locus: CPT2, CZIB, DMRTB1, ECHDC2, GLIS1, LRP8, MAGOH, PODN, SCP2, SLC1A7, ZYG11A, ZYG11B
Most likely causal gene: CPT2
GWAS Phenotype: Metabolite levels (cys-gly, oxidized)
Genes in Locus: ACSF3, ANKRD11, CDH15, CDK10, CHMP1A, CPNE7, DBNDD1, DEF8, DPEP1, ENSG00000198211, ENSG00000288715, FANCA, GAS8, MC1R, PRDM7, RPL13, SLC22A31, SPATA2L, SPATA33, SPG7, SPIRE2, TCF25, TUBB3, VPS9D1, ZNF276, ZNF778
Most likely causal gene: DPEP1
GWAS Phenotype: Metabolite levels (Fibrinopeptide A (7-16))
Genes in Locus: EGF, ELOVL6, ENPEP, PITX2
Most likely causal gene: ENPEP
GWAS Phenotype: Mean platelet volume during the postpartum period
Genes in Locus: AMN, BAG5, CDC42BPB, CKB, COA8, EIF5, ENSG00000256500, ENSG00000291313, EXOC3L4, LBHD2, MARK3, RCOR1, TNFAIP2, TRAF3, TRMT61A
Most likely causal gene: EXOC3L4
GWAS Phenotype: COVID-19 hospitalization or osteoarthritis (MTAG)
Genes in Locus: ALS2CL, CCR1, CCR2, CCR3, CCR5, CCR9, CCRL2, CXCR6, ENSG00000206549, ENSG00000283877, FAM240A, FYCO1, LRRC2, LTF, LZTFL1, PRSS50, RTP3, SACM1L, SLC6A20, TDGF1, TMIE, XCR1
Most likely causal gene: FYCO1
GWAS Phenotype: Metabolite levels (cysteine-glutathione disulfide)
Genes in Locus: ADORA2A, CABIN1, ENSG00000286070, GGT1, GGT5, GUCD1, KIAA1671, LHFPL7, LRRC75B, PIWIL3, SGSM1, SNRPD3, SPECC1L, SPECC1L-ADORA2A, SUSD2, UPB1
Most likely causal gene: GGT1
GWAS Phenotype: Metabolite levels (imidazole lactate; imidazolelactate)
Genes in Locus: CCDC113, CNOT1, GINS3, GOT2, NDRG4, PRSS54, SETD6, SLC38A7
Most likely causal gene: GOT2
GWAS Phenotype: Immature reticulocyte forward scatter
Genes in Locus: ABT1, BTN1A1, BTN2A1, BTN2A2, BTN3A1, BTN3A2, BTN3A3, CARMIL1, ENSG00000282988, ENSG00000290217, H1-1, H1-2, H1-3, H1-4, H1-6, H2AC1, H2AC4, H2AC6, H2AC7, H2AC8, H2BC1, H2BC10, H2BC3, H2BC4, H2BC5, H2BC6, H2BC7, H2BC8, H2BC9, H3C1, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H4C1, H4C2, H4C3, H4C4, H4C5, H4C6, H4C7, H4C8, HFE, HMGN4, SCGN, SLC17A1, SLC17A2, SLC17A3, SLC17A4, TRIM38
Most likely causal gene: HFE
GWAS Phenotype: Prostate cancer
Genes in Locus: EPB41L5, GLI2, INHBB, RALB, TMEM185B
Most likely causal gene: INHBB
GWAS Phenotype: Prostate-specific antigen levels
Genes in Locus: ACP4, ASPDH, C19orf81, C19orf84, CD33, CLDND2, CLEC11A, CTU1, EMC10, ENSG00000261341, ENSG00000269403, ENSG00000269741, ETFB, GARIN5A, GPR32, IGLON5, JOSD2, KLK1, KLK10, KLK11, KLK12, KLK13, KLK14, KLK15, KLK2, KLK3, KLK4, KLK5, KLK6, KLK7, KLK8, KLK9, LIM2, LRRC4B, MYBPC2, NKG7, SHANK1, SIGLEC10, SIGLEC7, SIGLEC9, SIGLECL1, SYT3, VSIG10L
Most likely causal gene: KLK3
GWAS Phenotype: Mean platelet volume during the postpartum period
Genes in Locus: ADPRHL1, ATP11A, ATP4B, CUL4A, DCUN1D2, F10, F7, GAS6, GRK1, GRTP1, LAMP1, MCF2L, PCID2, PROZ, TFDP1, TMCO3, TMEM255B
Most likely causal gene: LAMP1
GWAS Phenotype: Triglyceride to HDL cholesterol ratio
Genes in Locus: CACNG6, CACNG7, CACNG8, CDC42EP5, CNOT3, KIR2DL1, KIR2DL3, KIR3DL3, LAIR1, LAIR2, LENG1, LENG8, LENG9, LILRA1, LILRA2, LILRA4, LILRA5, LILRA6, LILRB1, LILRB2, LILRB3, LILRB4, LILRB5, MBOAT7, MYADM, NDUFA3, NLRP12, OSCAR, PRKCG, PRPF31, RPS9, TARM1, TFPT, TMC4, TSEN34, TTYH1, VSTM1
Most likely causal gene: LILRB5
GWAS Phenotype: Multi-trait sex score
Genes in Locus: BMP8A, BMP8B, HEYL, HPCAL4, MACF1, MFSD2A, MYCL, NT5C1A, OXCT2, PABPC4, PPIE, TRIT1
Most likely causal gene: MACF1
GWAS Phenotype: Metabolite levels (N-acetylcitrulline)
Genes in Locus: ACTG2, ALMS1, C2orf78, CCT7, DGUOK, DUSP11, EGR4, FBXO41, NAT8, NAT8B, NOTO, PRADC1, SMYD5, STAMBP, TET3, TPRKB
Most likely causal gene: NAT8
GWAS Phenotype: Eosinophil side fluorescence distribution width
Genes in Locus: CACNG6, CACNG7, CACNG8, CNOT3, DPRX, LENG1, LILRA5, LILRA6, LILRB2, LILRB3, LILRB5, MBOAT7, MYADM, NDUFA3, NLRP12, OSCAR, PRKCG, PRPF31, RPS9, TARM1, TFPT, TMC4, TSEN34, VSTM1, ZNF331, ZNF525, ZNF761, ZNF765, ZNF813, ZNF845
Most likely causal gene: NLRP12
GWAS Phenotype: Metabolite levels (sarcosine (N-Methylglycine); sarcosine)
Genes in Locus: ABO, ADAMTS13, ADAMTSL2, BRD3, BRD3OS, CACFD1, DBH, FAM163B, MED22, MYMK, REXO4, RPL7A, SARDH, SLC2A6, STKLD1, SURF1, SURF2, SURF4, SURF6, VAV2, WDR5
Most likely causal gene: SARDH
GWAS Phenotype: Metabolite levels (N-acetyltryptophan)
Genes in Locus: CARMIL1, ENSG00000282988, ENSG00000290217, H1-1, H1-2, H1-3, H1-4, H1-6, H2AC1, H2AC4, H2AC6, H2AC7, H2AC8, H2BC1, H2BC10, H2BC3, H2BC4, H2BC5, H2BC6, H2BC7, H2BC8, H2BC9, H3C1, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H4C1, H4C2, H4C3, H4C4, H4C5, H4C6, H4C7, H4C8, HFE, SCGN, SLC17A1, SLC17A2, SLC17A3, SLC17A4, TRIM38
Most likely causal gene: SLC17A1
GWAS Phenotype: Accessory basal nucleus volume
Genes in Locus: BANK1, MANBA, NFKB1, SLC39A8, UBE2D3
Most likely causal gene: SLC39A8
GWAS Phenotype: Multi-trait sum score
Genes in Locus: ABHD1, AGBL5, ATRAID, C2orf16, CAD, CCDC121, CENPA, CGREF1, DNAJC5G, DPYSL5, EIF2B4, EMILIN1, FNDC4, GCKR, GPN1, GTF3C2, IFT172, KCNK3, KHK, KRTCAP3, MAPRE3, MPV17, NRBP1, OST4, PPM1G, PREB, PRR30, SLC30A3, SLC35F6, SLC5A6, SNX17, SUPT7L, TCF23, TMEM214, TRIM54, UCN, ZNF512, ZNF513
Most likely causal gene: TRIM54