Question: what are autoimmune blood disorders

Reference:
 Autoimmune disorders Summary An autoimmune disorder occurs when the body's immune system attacks and destroys healthy body tissue by mistake. There are more than 80 types of autoimmune disorders. Causes The blood cells in the body's immune system help protect against harmful substances. Examples include bacteria, viruses, toxins, cancer cells, and blood and tissue from outside the body. These substances contain antigens. The immune system produces antibodies against these antigens that enable it to destroy these harmful substances. When you have an autoimmune disorder, your immune system does not distinguish between healthy tissue and antigens. As a result, the body sets off a reaction that destroys normal tissues. The exact cause of autoimmune disorders is unknown. One theory is that some microorganisms (such as bacteria or viruses) or drugs may trigger changes that confuse the immune system. This may happen more often in people who have genes that make them more prone to autoimmune disorders. An autoimmune disorder may result in: The destruction of body tissue Abnormal growth of an organ Changes in organ function An autoimmune disorder may affect one or more organ or tissue types. Areas often affected by autoimmune disorders include: Blood vessels Connective tissues Endocrine glands such as the thyroid or pancreas Joints Muscles Red blood cells Skin A person may have more than one autoimmune disorder at the same time. Common autoimmune disorders include: Addison disease Celiac disease - sprue (gluten-sensitive enteropathy) Dermatomyositis Graves disease Hashimoto thyroiditis Multiple sclerosis Myasthenia gravis Pernicious anemia Reactive arthritis Rheumatoid arthritis Sjogren syndrome Systemic lupus erythematosus Type I diabetes Symptoms Symptoms will vary, based on the type and location of the faulty immune response. Common symptoms include: Fatigue Fever General ill feeling (malaise) Joint pain Rash Exams and Tests The health care provider will do a physical exam. Signs depend on the type of disease. Tests that may be done to diagnose an autoimmune disorder include: Antinuclear antibody tests Autoantibody tests CBC Comprehensive metabolic panel C-reactive protein (CRP) Erythrocyte sedimentation rate (ESR) Urinalysis Treatment The goals of treatment are to: Reduce symptoms Control the autoimmune process Maintain the body's ability to fight disease Treatments will depend on your disease and symptoms. Types of treatments include: Supplements to replace a substance that the body lacks, such as thyroid hormone, vitamin B12, or insulin, due to the autoimmune disease Blood transfusions if blood is affected Physical therapy to help with movement if the bones, joints, or muscles are affected Many people take medicines to reduce the immune system's abnormal response. These are often called immunosuppressive medicines. Examples include corticosteroids (such as prednisone) and nonsteroid drugs such as azathioprine, cyclophosphamide, mycophenolate, sirolimus, or tacrolimus. Targeted drugs such as tumor necrosis factor (TNF) blockers and Interleukin inhibitors can be used for some diseases. Outlook (Prognosis) The outcome depends on the disease. Most autoimmune diseases are chronic, but many can be controlled with treatment. Symptoms of autoimmune disorders can come and go. When symptoms get worse, it is called a flare-up. Possible Complications Complications depend on the disease. Medicines used to suppress the immune system can cause severe side effects, such as higher risk of infections. When to Contact a Medical Professional Call your provider if you develop symptoms of an autoimmune disorder. Prevention There is no known prevention for most autoimmune disorders. Review Date 5/21/2017 Updated by: Laura J. Martin, MD, MPH, ABIM Board Certified in Internal Medicine and Hospice and Palliative Medicine, Atlanta, GA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. 

Answer: An autoimmune disorder occurs when the body's immune system attacks and destroys healthy body tissue by mistake. There are more than 80 types of autoimmune disorders. The blood cells in the body's immune system help protect against harmful substances. These substances contain antigens. The immune system produces antibodies against these antigens that enable it to destroy these harmful substances. When you have an autoimmune disorder, your immune system does not distinguish between healthy tissue and antigens. As a result, the body sets off a reaction that destroys normal tissues.