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L.N. 356 of 2021
OCCUPATIONAL HEALTH AND SAFETY AUTHORITY ACT 
(CAP. 424)
Protection of the Health and Safety of Workers from the risks 
related to Chemical Agents at Work (Amendment) 
Regulations, 2021
IN EXERCISE of the powers conferred by article 12 of the
Occupational Health and Safety Authority Act, the Deputy Prime
Minister and Minister for Health, after consultation with theOccupational Health and Safety Authority, has made the followin g
regulations:-
Citation. 
S.L. 424.24.1. The title of these regulations  is the Protection of the Health
and Safety of Workers from the risks related to Chemical Agents  at
Work (Amendment) Regulations, 2021, and these regulations shall be
read and construed as one with the Protection of the Health and Safety
of Workers from the risks related to Chemical Agents at Work
Regulations, hereinafter referred to as "the principal regulati ons".
Amends 
regulation 1 of the principal 
regulations.2. Sub-regulation (2) of regulation 1 of the principal regulations
shall be substituted by the following:
"(2) The scope of these regulations is to:
(a) lay down minimum requirements for the
protection of workers from ri sks to their health and safety
arising, or likely to arise, from the effects of chemical
agents that are present at the workplace or as a result of any
work activity involving chemical agents; 
(b) implement Directive 2014/27/EU of the
European Parliament and of the Council of 26 February2014 amending Council Directives 92/58/EEC, 92/85/EEC,94/33/EC, 98/24/EC and Directive 2004/37/EC of the
European Parliament and of the Council, in order to align
them to Regulation (EC) No 1272/2008 on classification,labelling and packaging of substances and mixtures; 
(c) implement Commission Directive (EU) 2017/
164 of 31 January 2017 establishing a fourth list ofindicative occupational exposure limit values pursuant to
Council Directive 98/24/EC, and amending Commission
Directives 91/222/EC, 2000/39/EC and 2009/161/EU;
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(d) implement Commission Directive (EU) 2019/
1831 of 24 October 2019 establishing a fifth list of
indicative occupational exposur e limit values  pursuant to
Council Directive 98/24/EC, and amending Commission
Directive 2000/39/EC.".
3. Schedule V of the principal regulations shall be substituted
by the following:
"SCHEDULE V
OCCUPATIONAL EXPOSURE LIMIT V ALUES  
EC No ( 1) CAS No ( 2) Name of agent Limit valuesNotation ( 3)
Eight hours ( 4) Short-term ( 5)
mg/ 
m3
(6)ppm 
(7)mg/m 3 
(6)ppm 
(7)
200-193-3 54-11-5 Nicotine 0.5 - - - skin
200-240-8 55-63-0 Glycerol trinitrate 0.095 0.01 0.19 0.02 skin
200-262-8 56-23-5 Carbon tetrachloride; 
Tetrachloromethane 6.4 1 32 5 skin
200-467-2  60-29-7 Diethylether 308 100 616 200 -
200-521-5  61-82-5 Amitrole 0.2 - - - -
200-539-3 62-53-3 Aniline (15) 7.74 2 19.35 5 skin
200-579-1 64-18-6 Formic acid 9 5 - - -
200-580-7  64-19-7 Acetic acid 25 10 50 20 -
200-659-6 67-56-1 Methanol 260 200 - - skin
200-662-2 67-64-1 Acetone 1210 500 - - -
200-663-8 67-66-3 Chloroform 10 2 - - skin
200-679-5 68-12-2N,N-
Dimethylformamide 15 5 30 10 skin
200-756-3 71-55-6 1,1,1-Trichloroethane 555 100 1100 200 -
200-817-4 74-87-3 Chloromethane 42 20 - -  -
200-821-6 74-90-8Hydrogen cyanide 
(as cyanide) 1 0.9 5 4.5  skin
200-830-5  75-00-3 Chloroethane 268 100 - - -
200-834-7 75-04-7 Ethylamine 9.4 5 - - -
200-835-2 75-05-8 Acetonitrile 70 40 - - skin
200-838-9 75-09-2Methylene chloride; 
Dichloromethane 353 100 706 200 skin
200-843-6 75-15-0 Carbon disulphide 15 5 - - skin
200-863-5 75-34-3 1,1-Dichloroethane 412 100 - - skin
200-864-0 75-35-4Vinylidene chloride; 
1,1- Dichloroethylene 8 2  20 5 -
200-870-3 75-44-5 Phosgene 0.08 0.02 0.4 0.1 -
200-871-9 75-45-6 Chlorodifluoromethane 3600 1000 - - -
200-875-0 75-50-3 Trimethylamine 4.9 2 12.5 5 -
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201-083-8 78-10-4 Tetraethyl orthosilicate 44 5 - - -
201-142-8 78-78-4 Isopentane 3000 1000 - - -
201-159-0 78-93-3 Butanone 600 200 900 300 -
201-176-3  79-09-4 Propionic acid 31 10 62 20 -
201-177-9 79-10-7Acrylic acid; Prop-2-
enoic acid 29 10 59(8) 20(8)-
201-188-9 79-24-3 Nitroethane 62 20 312 100 skin
201-245-8 80-05-7Bisphenol A; 4,4’- 
Isopropylidenediphenol 2(9)- - - -
201-297-1 80-62-6 Methyl methacrylate - 50 - 100 -
201-865-9  88-89-1 Picric acid 0.1 - - - -
202-049-5 91-20-3 Naphtalene 50 10 - - -
202-422-2 95-47-6 o-Xylene 221 50 442 100 skin
202-425-9  95-50-1 1,2-Dichlorobenzene 122 20 306 50 skin
202-436-9  95-63-6 1,2,4-Trimethylbenzene 100 20 - - -
202-500-6 96-33-3 Methyl acrylate 18 5 36 10 -
202-704-5  98-82-82-Phenyl-propane 
(Cumene) (15) 50 10 250 50 skin
202-705-0  98-83-9 2-Phenylpropene 246 50 492 100 -
202-716-0  98-95-3 Nitrobenzene 1 0.2 - -  skin
202-849-4  100-41-4 Ethylbenzene 442 100 884 200 skin202-981-2  101-84-8 Diphenyl ether 7 1 14 2 -
203-234-3 104-76-7 2-Ethylhexan-1-ol 5.4 1 - - -
203-300-1 105-46-4 sec-Butylacetate 241 50 723 150 -
203-313-2 105-60-2ε-Caprolactam (dust 
and vapour) 10 - 40 - -
203-388-1 106-35-4 Heptan-3-one 95 20 - - -
203-396-5 106-42-3 p-Xylene 221 50 442 100 skin
203-400-5 106-46-71,4-Dichlorobenzene; 
p- Dichlorobenzene 12 2 60 10 skin
203-403-1 106-49-0 4-aminotoluene 4.46 1 8.92 2 skin
203-453-4 107-02-8Acrolein; 
Acrylaldehyde; 
Prop-2-enal 0.05 0.02 0.12 0.05 -
203-470-7  107-18-6 Allyl alcohol 4.8 2 12.1 5 skin
203-473-3 107-21-1 Ethylene glycol 52 20 104 40 skin
203-481-7  107-31-3 Methyl formate 125 50 250 100 skin
203-539-1 107-98-2 1-Methoxy-2-propanol 375 100 568 150 skin
203-545-4 108-05-4 Vinyl acetate 17.6 5 35.2 10 skin
203-550-1 108-10-1 4-Methylpentan-2-one 83 20 208 50 -
203-576-3 108-38-3 m-Xylene 221 50 442 100 skin
203-585-2  108-46-3 Resorcinol 45 10 - - skin
203-603-9 108-65-62-Methoxy-1-
methylethyl acetate 275 50 550 100 skin
203-604-4 108-67-8Mesitylene 
(Trimethylbenzes) 100 20 - - -
203-625-9  108-88-3 Toluene 192 50 384 100 skin
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203-628-5  108-90-7 Monochlorobenzene 23 5 70 15 -
203-631-1 108-94-1 Cyclohexanone 40.8 10 81.6 20 skin
203-632-7  108-95-2 Phenol 8 2 16 4  skin
203-692-4 109-66-0 Pentane 3000 1000 - - -
203-713-7  109-86-4 2-Methoxyethanol - 1 - -  skin
203-716-3 109-89-7 Diethylamine 15 5 30 10 -
203-726-8 109-99-9 Tetrahydrofuran 150 50 300 100 skin
203-737-8 110-12-3 5-Methylhexan-2-one 95 20 - - -
203-745-1  110-19-0 Isobutyl acetate 241 50 723 150 -203-767-1  110-43-0 Heptan-2-one 238 50 475 100 skin
203-772-9  110-49-6 2-Methoxyethyl acetate - 1 - -  skin
203-777-6  110-54-3 n-Hexane 72 20 - - -
203-788-6 110-65-6 But-2-yne-1,4-diol 0.5 - - - -
203-804-1  110-80-5 2-Ethoxyethanol 8 2 - -  skin
203-806-2 110-82-7 Cyclohexane 700 200 - - -
203-808-3 110-85-0 Piperazine 0.1 - 0.3 - -
203-809-9 110-86-1 Pyridine 15 5 - - -
203-815-1 110-91-8 Morpholine 36 10 72 20 -203-839-2 111-15-9 2-Ethoxyethyl acetate 11 2 - - skin
203-905-0 111-76-2 2-Butoxyethanol 98 20 246 50 skin
203-906-6 111-77-32-(2-
Methoxyethoxy)ethanol 50.1 10 - - skin
203-933-3  112-07-2 2-Butoxyethyl acetate 133 20 333 50 skin203-961-6 112-34-52-(2-
Butoxyethoxy)ethanol 67.5 10 101.2 15 -
204-065-8 115-10-6 Dimethylether 1920 1000 - - -
204-428-0 120-82-1 1,2,4-Trichlorobenzene 15.1 2 37.8 5 skin
204-469-4 121-44-8 Triethylamine 8.4 2 12.6 3 skin
204-633-5 123-51-3 Isoamyl alcohol 18 5 37 10 -
204-658-1 123-86-4 n-Butyl acetate 241 50 723 150 -
204-661-8 123-91-1 1,4-Dioxane 73 20 - - -
204-662-3 123-92-2 Isopentylacetate 270 50 540 100 -
204-696-9  124-38-9 Carbon dioxide 9000 5000 - - -
204-697-4 124-40-3 Dimethylamine 3.8 2 9.4 5 -
204-825-9 127-18-4 Tetrachloroethylene 138 20 275 40 skin
204-826-4 127-19-5N,N-
Dimethylacetamide 36 10 72 20 skin
205-438-8 140-88-5 Ethyl acrylate 21 5 42 10 -
205-480-7 141-32-2 n-Butyl acrylate 11 2 53 10 -
205-483-3 141-43-5 2-Aminoethanol 2.5 1 7.6 3 skin205-500-4 141-78-6 Ethyl acetate 734 200 1468 400 -
205-563-8 142-82-5 n-Heptane 2085 500 - - -
205-599-4  143-33-9Sodium cyanide (as 
cyanide) 1 - 5 -  skin
205-634-3 144-62-7 Oxalic acid 1 - - - -
205-792-3 151-50-8Potassium cyanide (as 
cyanide) 1 - 5 -  skin
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206-992-3 420-04-2 Cyanamide 1 0.58 - -  skin
207-069-8 431-03-8 Diacetyl; Butanedione 0.07 0.02 0.36 0.1 -
207-343-7  463-82-1 Neopentane 3000 1000 - - -
208-394-8 526-73-81,2,3-
Trimethylbenzene 100 20 - - -
208-793-7 541-85-5 5-Methylheptan-3-one 53 10 107 20 -210-866-3 624-83-9 Methyl isocyanate - - - 0.02 -
210-946-8 626-38-0 1-Methylbutyl acetate 270 50 540 100 -
211-047-3 628-63-7 Pentyl acetate 270 50 540 100 -
211-128-3 630-08-0 Carbon monoxide 23 20 117 100 -
212-828-1 872-50-4n-Methyl-2-
pyrrolidone 40 10 80 20 skin
215-137-3 1305-62-0 Calcium dihydroxide 1(
10) - 4(10)- -
215-138-9 1305-78-8 Calcium oxide 1(10) - 4(10)- -
215-236-1  1314-56-3Diphosphorus 
pentaoxide 1 - - - -
215-242-4  1314-80-3Diphosphorus 
pentasulphide 1 - - - -
215-293-2 1319-77-3 Cresols (all isomers) 22 5 - - -
215-535-7  1330-20-7Xylene, mixed 
isomers, pure 221 50 442 100 skin
216-653-1  1634-04-4Tert-Butyl methyl 
ether 183.5 50 367 100 -
222-995-2 3689-24-5 Sulphotep 0.1 - - - skin
231-116-1 7440-06-4 Platinum (metallic) 1 - - - -
231-131-3 7440-22-4 Silver, metallic 0.1 - - - -
231-131-3Silver (soluble 
compounds as Ag) 0.01 - - - -
231-195-2 7446-09-5 Sulphur dioxide 1.3 0.5 2.7 1 -
231-484-3  7580-67-8 Lithium hydride - - 0.02(9)- -
231-595-7  7647-01-0 Hydrogen chloride 8 5 15 10 -
231-633-2  7664-38-2 Orthophosphoric acid 1 - 2 - -
231-634-8 7664-39-3 Hydrogen fluoride 1.5 1.8 2.5 3 -
231-635-3 7664-41-7 Ammonia, anhydrous 14 20 36 50 -
231-639-5 7664-93-9Sulphuric acid mist 
(11)(12) 0.05 - - - -
231-714-2  7697-37-2 Nitric acid - - 2.6 1 -
231-778-1 7726-95-6 Bromine 0.7 0.1 - - -
231-954-8 7782-41-4 Fluorine 1.58 1 3.16 2 -
231-959-5 7782-50-5 Chlorine - - 1.5 0.5 -
231-977-3  7783-06-4 Hydrogen sulphide 7 5 14 10 -
231-978-9 7783-07-5 Dihydrogen selenide 0.07 0.02 0.17 0.05 -
232-260-8 7803-51-2 Phosphine 0.14 0.1 0.28 0.2 -
232-319-8 8003-34-7Pyrethrum (purified of 
sensitising lactones) 1 - - - -
233-046-7  10025-87-3 Phosphoryl trichloride 0.064 0.01 0.12 0.02 -
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233-060-3  10026-13-8Phosphorus 
pentachloride 1 - - - -
233-113-0  10035-10-6 Hydrogen bromide - - 6.7 2 -
233-271-0  10102-43-9Nitrogen 
monoxide(13) 2.5 2 - - -
233-272-6  10102-44-0 Nitrogen dioxide 0.96 0.5 1.91 1 -
247-852-1 26628-22-8 Sodium azide 0.1 - 0.3 - skin
252-104-2 34590-94-8(2-Methoxy-
methylethoxy)- 
propanol 308 50 - - skin
262-967-7 61788-32-7Terphenyl, 
hydrogenated 19 2 48 5 -
620-11-1 3-Pentylacetate 270 50 540 100 -
625-16-1 Amylacetate, tert 270 50 540 100 -
Fluorides, inorganic 2.5 - - - -
Barium (soluble 
compounds as Ba) 0.5 - - - -
Chromium Metal, 
Inorganic Chromium 
(II) Compounds and 
Inorganic Chromium
(III) Compounds 
(insoluble)2- - - -
Tin (inorganic 
compounds as Sn) 2 - - - -
Mercury and divalent 
inorganic mercury 
compounds including 
mercuric oxides and 
mercuric chloride 
(measured 
as mercury) (14)0.02
Manganese and 
inorganic manganese 
compounds (as 
manganese) 0.2 (9)
0.05(10)
VERŻJONI ELETTRONIKA
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(1) EC No: European Community (EC) number, the numer ical identifi er for substances within the European Union.
(2) CAS No: Chemical Abstract Service Registry Number.
(3) A skin notation as signed to the occupati onal exposure limit v alue indicates the possib ility of signifi cant uptake
through the skin.
(4) Measured or calculated in rela tion to a reference period of eight-hours as a time-weighted average.
(5) Short-term exposure limit (STEL). A limit value above which exposure should not occur and is related to a 15- 
 minute period, unless otherwise sp ecified. 
(6) mg/m 3: milligrams per cubic metre  of air at 20 °C and 101.3 KPa.
(7) ppm: parts per million by volume in air (ml/m 3).
(8) Short-term exposure limit value in relation to a reference period of 1 minute.
(9) Inhalabl e fraction.
(10)Respirable fraction. 
(11)When selecting an appropriate exposure monitoring method , account should be taken of potential limitations 
 and interferences that may arise in the presence of other sulp hur compounds.
(12)The mist is defined as the thoracic fraction.
(13)Established in accordance with the Annex to Directive.
(14)During exposure monitoring for mercury and its divalent inorganic compounds, account should be taken of
 relevant biological monitoring te chniques that complement the OELV.
(15)During exposure monitoring, account should be taken of relevant biological monitoring values as suggested by
 the Scientific Comm ittee on Occupational Exposure Limits for C hemical Agents (SCOEL).".
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