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Harbouring doubts as to the validity of Implementing Decision 2015/789, the Tribunale amministrativo regionale per il Lazio (Regional Administrative Court, Lazio), having suspended the implementation of the national measures at issue in so far as they order the uprooting of all host plants within a radius of 100 metres of the infected plants, decided to stay the proceedings and to refer the following questions for a preliminary ruling: ‘(1) Do Directive 2000/29/EC …, in particular [Article] 11(3) [to Article] 13c(7), and [Article] 16(1) [to] (3) and (5) thereof, and the principles of proportionality, logic and reasonableness preclude the application of Article 6(2) and (4) of Implementing Decision [2015/789], as implemented in the Italian legal order by Article 8(2) and (4) of the Decree of [19 June 2015], in so far as it requires that host plants, regardless of their health status, be immediately removed within a radius of 100 metres around the plants which have been tested and found to be infected by the specified organism, and at the same time provides that the Member State is to carry out appropriate phytosanitary treatments prior to the removal of plants referred to in paragraph 2 against the vectors of the specified organism and plants that may host those vectors and that those treatments may include, as appropriate, removal of plants? (2) Does Directive 2000/29 …, in particular Article 16(1) thereof, preclude, in particular by use of the phrase ‘necessary measures to eradicate, or if that is impossible, inhibit the spread of the harmful organisms concerned’, the application of Article 6(2) of Decision [2015/789], as implemented in the Italian legal order by Article 8(2) of the Decree of [19 June 2015], in so far as it provides for the immediate removal of host plants, regardless of their health status, within a radius of 100 metres around the plants which have been tested and found to be infected? (3) Do Articles 16(1) [to] (3) and (5) of Directive 2000/29 … and the principles of proportionality and logic and the right to due process preclude an interpretation of Article 6(2) and (4) of Implementing Decision [2015/789] — as implemented in the Italian legal order by Article 8(2) and (4) of the Decree of [19 June 2015] — to the effect that the eradication measure referred to in Article 6(2) can be imposed [prior to the application of] the preventive measures provided for in Articles 6(3) and (4) and independently of their application? (4) Do the precautionary principle and the principles of adequacy and proportionality preclude the application of Article 6(2) [to] (4) of Implementing Decision [2015/789], as implemented in the Italian legal order by Article 8(2) and (4) of the Decree of [19 June 2015], in so far as it imposes measures to eradicate host plants within a radius of 100 metres around the plants which have been found to be infected by the organism [Xylella], without adequate scientific evidence … to demonstrate with certainty the causal relationship between the presence of the organism and the desiccation of the plants deemed to be infected? (5) Do the second paragraph of Article 296 TFEU and Article 41 of the Charter of Fundamental Rights of the European Union [‘the Charter’] preclude the application of Article 6(2) and (4) of Implementing Decision [2015/789], in so far as it provides for the immediate removal of the hosts plants, regardless of their health status, within a radius of 100 metres around the plants which have been tested and found to be infected, since it fails to provide an adequate statement of reasons? (6) Do the principles of adequacy and proportionality preclude the application of Implementing Decision [2015/789] — as implemented in the Italian legal order by the Decree of [19 June 2015] — which provides measures for the removal of host plants, regardless of their health status, of plants known to be infected by the specified organism, and of plants showing symptoms indicating possible infection by the organism [Xylella], or suspected of being infected by that organism, without providing for any form of compensation for the owners not responsible for the spread of the organism in question?’