Member state/EEA Applicant/Marketing Authorisation Holder Product name INN Strength Pharmaceutical form Animal species Frequency and route of administration Recommended dose Withdrawal period(s)/Indications

Austria Chevita Tierarzneimittel Gesellschaft m.b.H. Kaplanstraße 10 AT 4600 Wels AUSTRIA Doxymax 500 mg/g - Pulver zur Herstellung einer Lösung zum Einnehmen für Schweine und Hühner Doxycycline hyclate 500 mg/g Oral powder Pigs, Chicken (broiler) Chicken: 3-5 days, oral via drinking water Chicken: 25mg doxycyclin hyclat/kg BW/day = 1g powder/20 kg/day Meat and offal: Chicken (Broiler) 5 days, Eggs: not for use in laying hen Indications: infection of respiratory tract caused by Mycoplasma spp. (M.gallisepticum, Escherichia coli, Septicamia caused by Pasteurella multocida

Belgium DOPHARMA B.V. Zalmweg 24, P.O. BOX 205 4940 AE Raamsdonksveer THE NETHERLANDS Doxycycline 50 % Dopharma Doxycycline hyclate 500 mg/g Water soluble powder Calves, porcine, poultry Poultry: 50mg/kg/day 3-5 days 500 g/1 000 L drinking water Meat and offal: 6 days Indications: infections by micro-organisms in respiratory or gastro-intestinal system

Belgium VIRBAC S.A. 1ère avenue - 2065 m - L.I.D. 06516 CARROS FRANCE Pulmodox 50 % Doxycycline hyclate 500 mg/g Water soluble powder Calves, porcine, poultry Poultry: 50 mg/kg/day 3-5 days 500 g/1 000 L drinking water Meat and offal: 6 days Indications: infections by micro-organisms in respiratory or gastro-intestinal system

Belgium Eurovet Animal Health B.V. Handelsveg 25 PO Box 179 5530 AD Bladel THE NETHERLANDS Soludox 50 % Doxycycline hyclate 500mg/g Water soluble powder Porcine, poultry Poultry: 10-20mg/kg/day 3-4 days 100-200 g/1 000 L drinkwater Meat and offal: 3 days/10mg/kg 12 days/20mg/kg Indications: respiratory diseases

Belgium Eurovet Animal Health B.V. Handelsveg 25 PO Box 179 5530 AD Bladel THE NETHERLANDS Soludox 15 % ad. us. vet.. Doxycycline hyclate 150mg/g Water soluble powder Porcine, calves, poultry, fancy birds, pigeons Poultry: 10-20mg/kg/day 3-5 days 500 g/1 000 L drinkwater Meat and offal: 7 days Indications: respiratory diseases caused by germs

Belgium Huvepharma N.V. Uitbreidingstraat 80 2600 Antwerpen BELGIUM Hydrodoxx 500 mg/g water-soluble powder Doxycycline hyclate 500mg/g doxycycline hyclate Powder for oral solution Chickens (broilers) & Pigs (fattening pigs) Oral (drinking water) 20 mg doxycycline (hyclate)/kg x 3-5 days Meat and offal: Chickens: 6 days Do not use in laying birds producing eggs for human consumption Indications: Chickens (broilers): Prevention and treatment of Chronic Respiratory Disease (CRD) caused by Mycoplasma gallisepticum.

Bulgaria Farma Sis OOD 4 San Stefano Str. Dobrich BULGARIA Doxinyl 10 % Oral Suspension Doxycycline hyclate 100mg/ml Oral Suspension Poultry Via drinking water 50 -100 ml Doxinyl 10 % in 100 l drinking water per day (50-100 mg Doxycycline in 1 l drinking water) 3-5 days Meat - 5 days

Bulgaria Farma Sis OOD 4 San Stefano Str. Dobrich BULGARIA Cyvadox 10 % Doxycycline hyclate 100mg/ml Oral Suspension Poultry Via drinking water 0,5-1 ml in 1 l drinking water per day \3-5 days\ 50-100 mg Doxycycline Meat - 7 days

Bulgaria DOPHARMA B.V. Zalmweg 24, P.O. BOX 205 4940 AE Raamsdonksveer THE NETHERLANDS Doxycycline 50 % w.s.p. Doxycycline hyclate 500mg/g Water soluble powder Poultry Via drinking water 500g Doxycycline 50 % w.s.p. in 100 l drinking water/3-5 days/ Meat - 4 days

Bulgaria Farmavet OOD 40 Otec Paisij Str. Shumen BULGARIA Doxycycline 20 % Pulvis solubilis Doxycycline hyclate 200mg/g Water soluble powder Poultry Via drinking water 50g Doxycycline 20 % in 100l drinking water/3-5 days/ Meat - 7 days

Bulgaria Interchemie Werken De Adelaar BV Hosterweg 26a 5811 Ccastenray THE NETHERLANDS Doxy – WS Doxycycline hyclate 200mg/g Water soluble powder Poultry Via drinking water 1kg Doxy-WS in 2 000-4 000 l drinking water Meat - 7 days

Bulgaria Ceva Sante Animale France La Balastiere 33501 Libourne Cedex FRANCE Doxyvit 50 % WSP Doxycycline hyclate 500 mg/g Water soluble powder Poultry Via drinking water 2-3g Doxyvit 50 % WSP in 10 l. Drinking water - 5 days/equivalent to 100-150 mg Doxycycline in 1l water Meat - 7 days

Bulgaria Ceva Sante Animale France La Balastiere 33501 Libourne Cedex FRANCE Doxyvit 100 Doxycycline hyclate 100 mg/g Water soluble powder Poultry Via drinking water 10 mg Doxyvit per kg body weight per day Meat - 7 days

Bulgaria Vetpartners OOD Ivan Asen Str. 4270 Parvomaj BULGARIA Polidoxichem 500/WSP Doxycycline hyclate 500 mg/g Water soluble powder Poultry Via drinking water 50-100 mg Doxycycline in 1l drinking water/3-5 days/ equivalent to 0,1-0,2g Polidoxichem 500 WSP in 1l drinking water per day Meat - 7 days

Bulgaria Biovet AD 39 Petar Rakov Str. 4550 Peshtera BULGARIA Vibravet 10 % Water soluble premix Doxycycline hyclate 100 mg/g Water soluble powder Poultry Via drinking water 1g Vibravet 10 % in 1l drinking water /=67-100 mg Doxycycline/per day. 5 days Meat - 7 days

Cyprus PREMIER SHUKUROGLOU LTD HIPRADOXI -S Doxycycline hyclate 100 mg Oral solution Pigs, Chicken (broiler) By oral route, via drinking water Broilers: 50-100 mg doxycycline hyclaye/L water for 3-5 days Broilers: meat: 5 days Pigs: meat:6 days

Czech republic Industria Italiana Integratori TREI S.p.A. Viale Corassori 62 41100 Modena ITALY DOXIPAN 20 Doxycycline hyclate 20 g/100 g Powder for oral solution Chicken-broiler, turkey Administer orally via drinking water for 5 days. Broiler: 5-7,5 g of product/10 l drinking water turkey: 10 – 20 mg doxycycline/kg bodyweight Chicken broiler: Meat and offal: 5 days. Turkey: meat and offal: 10 days Indications: Chicken broilers: Chronic respiratory diseases and associated infections. Turkeys: Diseases caused G+ and G- micro-organisms and mycoplasmas, especially respiratory and articular syndrome caused by mycoplasmas and/or staphylococcus.

Czech republic Pharmagal s.r.o., Murgašova 5, 949 01 Nitra, SLOVAK REPUBLIC DOXYGAL Doxycycline hyclate 50 mg/1 g Powder for oral solution Poultry Administer orally via drinking water for 3-5 days. Therapeutically- preventive: 50 mg doxycycline/1 l drinking water Therapeutically: 100 mg doxycycline/1 l drinking water Meat and offal: 7 days. Not permitted for use in laying hens from which eggs are produced for human consumption. Indications: Used for the treatment of the secondary bacterial infections following to viral origin diseases. Poultry: CRD (mycoplasmosis), colibacillosis

Czech republic Lavet Pharmaceuticals Ltd., 1161 Budapest Ottó u. 14, HUNGARY DOXYVIT 40 % Doxycicline hyclate 40g/100g Powder for oral solution Chicken-broiler, turkey Administer orally via drinking water for 3-5 days. 1.Continuous therapy: 1,0g DOXYVIT 40 % per 3-6 L of drinking water 2.Pulse therapy: 10-20 mg doxycycline / kg b.w., intervals 4-8 hours. Chicken broiler, turkey: Meat and offal: 4 days. Not permitted for use in laying hens from which eggs are produced for human consumption. Indications: Treatment and prevention of respiratory, intestinal and systemic infections caused by microorganisms susceptible to doxycycline in broilers and turkeys. Chronic respiratory disease (Mycoplasma gallisepticum, Escherichia coli) Aerosaculitis (Mycoplasma meleagridis) Infectious synovitis (Mycoplasma synoviae) Fowl cholera (Pasterella multocida) Bordetella turkey infections (Bordetella avium) Infectious coryza (Haemophilus paragallinarum) Colibacillosis (Eschrichia coli) Necrotic enteritidis (Clostridium perfringens) Chlamydiosis (Chlamydia psittaci)

Czech republic Laboratorios Karizoo S.A Polígono Industrial La Borda Mas Pujades 11-12 08140 Caldes de Montbui Barcelona SPAIN KARIDOX 100 mg/ml Doxycycline hyclate 100 mg/1 ml Oral solution Chicken-broiler Administer orally via drinking water for 3-5 days. 10-20 mg doxycycline/kg bodyweight/day (i.e.. 0,5-1,0 ml of product/l of drinking water/day). Chickens(broilers): Meat and offal: 7 days. Not permitted for use in laying hens from which eggs are produced for human consumption Indications: Prevention and treatment of chronic respiratory disease (CRD) and mycoplasmosis caused by microorganisms susceptible to doxycycline.

Czech republic Tekro, spol. s.r.o., Višňová 2/484, 140 00 Praha 4, CZECH REPUBLIC MEDITEK DOX 100 Doxycycline hyclate 100g/kg Powder for oral solution Broiler Administer orally via drinking water for 3-5 days. 10 mg Doxycycline hyclate/1kg bodyweight (1,0 kg of product / 1 000 l drinking water) Chickens (broilers): Meat and offal: 7 days Indications: Prevention and treatment of infection disease of the respiratory and gastrointestinal tract in pigs and broilers caused by the pathogens susceptible to doxycycline. It is efficient on the several bacteria resistant to first generation tetracyclines.

Czech republic CHEMO IBERICA, S.A. Gran Via Carlos III, 98 7a Edificio Trade 08028 Barcelona SPAIN ORIDOX 100 mg/ml, perorální roztok pro podání v pitné vodě pro brojlery a prasata Doxycycline hyclate 100 mg/1ml Oral solution Chicken-broiler Administer orally via drinking water for 3-5 days. 10-20 mg doxycycline/kg bodyweight/day (i.e.. 0,5-1,0 ml of product/ldrinking water/day Chickens (broilers): Meat and offal: 7 days. Eggs: Not permitted for use in laying hens from which eggs are produced for human consumption Indications: Prevention and treatment of chronic respiratory disease (CRD) and mycoplasmosis caused by microorganisms susceptible to doxycycline.

Czech republic VIRBAC S.A. 1ère avenue - 2065 m - L.I.D. 06516 CARROS FRANCE Pulmodox O.S.P. 5 % Doxycycline hyclate 0,05 g/1g Powder for oral solution Poultry Administer orally via drinking water for 3-5 days. Poultry till 2 weeks: 1 g of the product per L of drinking water and day Poultry over 2 weeks: 2 g of the product per L of drinking water and day Duration of the treatment: 3 - 5 days. Chicken (broilers): Meat and offal: 4 days, Not permitted for use in laying hens from which eggs are produced for human consumption. Indications: Treatment of respiratory infections caused by the pathogens susceptible to doxycycline and chickens (broilers).

Czech republic KELA Laboratoria n.v. Industrial Zone De Kluis St. Lenaartseweg 48 2320 Hoogstraten BELGIUM Respidox 5 % Doxycycline hyclate 50 mg / 1 g Powder for oral solution Poultry Administer orally via drinking water for 3 days. 2 g of product/l drinking water Poultry: Meat and offal: 7 days Not permitted for use in laying hens from which eggs are produced for human consumption. Indications: Treatment of the infections caused by the microrganisms susceptible to doxycycline. Poultry: CRD, colibacillosis, inflammation of nasal mucosa, synovitis, salmonelosis, fowl cholera, chlamydiosis

Czech republic COOPHAVET Saint Herblon 44150 Ancenis FRANCE RONAXAN P.S. 5 % Doxycycline hyclate 50 mg / 1 g Powder for oral solution Chickens Administer orally via drinking water for 5 days. 10 mg doxycycline / kg bodyweight. / day (i.e.. 1 g of product/5 kg bodyweight.) Chicken (broilers): Meat and offal: 4 days, Not permitted for use in laying hens from which eggs are produced for human consumption. Indications: Treatment of respiratory infections caused by the pathogens susceptible to doxycycline in chickens (broilers).

Czech republic LABORATORIOS CALIER, S.A. BARCELONÉS, 26 08520 Les Franqueses del Valles SPAIN Doxycycline Calier 500 mg/g Doxycycline hyclate 500 mg/g Water soluble powder Poultry Pigs Oral 3-5 days 20 mg/kg/day 6 days Prevention and treatment of Chronic Respiratory Disease (CRD) caused by Mycoplasma gallisepticum

Czech republic Ceva Animal Health Slovakia spol. s.r.o. Račianska 77 831 02 Bratislava SLOVENIA DOXYVIT 100 Doxycycline hydrocloride 100 g/1 000 g Powder for oral solution Poultry (chicken, turkey, goose) Administer orally via drinking water for 5 days. 10 mg doxycycline/kg bodyweight per day, i.e. 0,1 g DOXYVIT 100 / kg bodyweight Meat and offal: 7 days. Not permitted for use in laying hens from which eggs are produced for human consumption. Indications: Treatment and prevention of respiratory, intestinal and systemic infections caused by micro-organisms susceptible to doxycycline in hens, turkeys and gouses: chronical respiratory disease (Mycoplasma gallisepticum, Escherichia coli), aerosaculitis (Mycoplasma meleagridis), synovitis (Mycoplasma synoviae), fowl cholera (Pasteurella mul tocida), bordetela turkey infections (Bordetella avium), infectious coryza (Haemophilus paragallinarum), colibacillosis (Esccherichia coli), necrotic enteritis (Clostridium perfringens), chlamydiosis (Chlamydia psittaci), prevention in stress conditions (vaccination, changes in housing, transportation)

Denmark Laborartorios Karizoo S.A. Pol.Ind. La Borda c/Mas Pujades 11-12 Caldes de Montbui 08140 SPAIN Karidox Doxycycline hyclate 10 % Oral solution Chickens, swine Orally (drinking water) for 3 to 5 days In chickens: 10-20 mg doxycycline hyclate per kg bodyweight per day for 3 to 5 days (i.e. 0.5-1.0 ml product/litre water/day) Chickens for slaughter: 7 days Eggs: May not be administered to egg laying poultry if the eggs are intended for human use. Indications:Prevention and treatment of CRD and mycoplasmosis caused by microorgansisms sensitive to doxycycline.

Denmark CHEMO IBERICA, S.A. Gran Via Carlos III, 98 7a Edificio Trade 08028 Barcelona SPAIN Oridox Doxycycline hyclate 10 % Oral solution Chickens, swine Orally (drinking water) for 3 to 5 days In chickens: 10-20 mg doxycycline hyclate per kg bodyweight per day for 3 to 5 days (i.e. 0.5-1.0 ml product/litre water/day) Chickens for slaughter: 7 days Eggs: May not be administered to egg laying poultry if the eggs are intended for human use. Indications: Prevention and treatment of CRD and mycoplasmosis caused by microorgansisms sensitive to doxycycline.

Denmark Huvepharma N.V. Uitbreidingstraat 80 2600 Antwerpen BELGIUM HydroDoxx Doxycycline hyclate 500 mg/g doxycycline hyclate Powder for oral solution Chickens (broilers) & Pigs (fattening pigs) Oral (drinking water) 20 mg doxycycline (hyclate)/kg x 3-5 days Meat and offal: Chickens: 6 days Do not use in laying birds producing eggs for human consumption Indications: Chickens (broilers): Prevention and treatment of Chronic Respiratory Disease (CRD) caused by Mycoplasma gallisepticum.

Estonia Laboratorios Hipra S.A. Avda La Selva 135 17170 Amer (Girona) SPAIN Hipradoxi-S Doxycycline hyclate 100 mg/ml Concentrate for oral solution chicken (broilers) oral use via drinking water. 50 … 100 mg doxycycline/litre water Meat and offal: 5 days. Not authorised for use in laying birds producing eggs for human consumption. Indications: Colibacillosis, C.R.D. and associated infections.

Estonia Laboratorios Hipra S.A. Avda La Selva 135 17170 Amer (Girona) SPAIN Hipradoxi-P Doxycycline hyclate 100 mg/g powder for oral solution chicken (broilers) oral use via drinking water. 20 mg doxycycline/kg bw/day Meat and offal: 5 days. Not authorised for use in laying birds producing eggs for human consumption. Indications: Colibacillosis, C.R.D. and associated infections.

Estonia Maxx Pharma OÜ Kaluri tee 5 Haabneeme 74001 Viimsi Harjumaa ESTONIA Doxyprim 40 % Doxycycline hyclate 400 mg/g powder for oral solution chicken, turkeys oral use via drinking water. 10 … 20 mg/kg bw/day 5 days Meat and offal: 4 days. Not authorised for use in laying birds producing eggs for human consumption. Indications: For the treatment of respiratory, intestinal and systemic infections caused by doxycycline-sensitive organisms.

Estonia Zoovetvaru uusaru 5 76505 Saue Harjumaa ESTONIA Doxycin Doxycycline hyclate 200 mg/g powder for oral solution chicken (broilers) for oral administaration, via drinking water. 10 mg doxycycline/kg bw/day 3-5 days Meat and offal: 6 days. Do not use in laying birds producing eggs for human consumption. Indications: For the treatment of infections of the respiratory system and alimentary tract caused by microorganisms sensitive to doxycycline, including mycoplasmas, bordeteliosis, chlamydiosis, pasteurellosis anaerobic infections, salmonellosis, staphylococcosis, colibacillosis.

Estonia Dutch Farm Veterinary Pharmaceuticals B.V. Veemweg 1 3771 MT Barnevald THE NETHERLANDS Dutch Farm Doxycycline 20 % WSP Doxycycline hyclate 200 mg/g powder for oral solution poultry for oral administration, via drinking water. 15 mg Doxycycline hyclate/kg bw/day 3-5 days. Meat and offal: 7 days. Do not use in laying birds producing eggs for human consumption. Indications: For the treatment of infections caused by microorganisms sensitive to doxycycline, especially respiratory infections.

Germany LABORATORIOS CALIER, S.A. BARCELONÉS, 26 08520 Les Franqueses del Valles SPAIN DOXYCYCLINE CALIER 500 mg/g, Pulver zum Eingeben über das Trinkwasser für Huhn und Schwein Doxycycline hyclate 500 mg/g Water soluble powder Poultry Pigs Oral 3-5 days 20 mg/kg/day Meat and offal: 6 days Indications: Prevention and treatment of Chronic Respiratory Disease (CRD) caused by Mycoplasma gallisepticum

Germany Huvepharma N.V. Uitbreidingstraat 80 2600 Antwerpen BELGIUM HydroDoxx 500 mg/g Pulver zum Eingeben über das Trinkwasser Doxycycline hyclate 500 mg/g Powder for oral solution Chickens (broilers) & Pigs (fattening pigs) Oral (drinking water) 20 mg doxycycline (hyclate)/kg x 3-5 days Meat and offal: Chickens: 6 days Do not use in laying birds producing eggs for human consumption Indications: Chickens (broilers): Prevention and treatment of Chronic Respiratory Disease (CRD) caused by Mycoplasma gallisepticum.

Greece Durden Trading Limited 12, Kennedy Av. Nicosia CYPRUS Stardox Doxycycline hyclate 500 mg/g Powder for oral solution Chickens(broiler) Non –egg laying chickens Calves pigs In drinking water 20 mg/kg X 4-7 days Meat and offal: 14 days Indications: CRD caused by Mycoplasma gallisepticum colibacilosis

Greece NEW VET A.E Fleming 15 15123 Marousi Attikis GREECE Nexyclin Doxycycline hyclate 400 mg/g Powder for oral solution Chickens(broiler) Turkeys pigs In drinking water 20 mg/kg Meat and offal: 4 days Indications: Respiratory infections caused by Mycoplasma gallisepticum, E.coli Pasteurella multocida, Chlamydia psittaci

Greece VIRBAC S.A. 1ère avenue - 2065 m - L.I.D. 06516 CARROS FRANCE Pulmodox Doxycycline hyclate 500 mg/g Powder for oral solution Chickens(broiler) Non –egg laying chickens Calves pigs In drinking water 10 mg/kg X 3-5 days Meat and offal: 9 days Indications: Respiratory infections caused by Mycoplasma spp, E.coli, Haemophilus paragalinarum, Bordetella avium Enteritis caused by Clostridium perfringens and colinum

Greece Nutri-Biomed Hellas LTD 1, V. Hugo & Chlois Metamorfosi Attikis 14452 Athens GREECE Doxyveto Doxycycline hyclate 500 mg/g Powder for oral solution Chickens(broiler) Non –egg laying chickens Calves pigs In drinking water 25 mg/kg X 3-5 days Meat and offal: 9 days Indications: Respiratory infections caused by Mycoplasma spp, E.coli, Haemophilus paragalinarum, Bordetella avium Enteritis caused by Clostridium perfringens and colinum

Greece DOPHARMA B.V. Zalmweg 24, P.O. BOX 205 4940 AE Raamsdonksveer THE NETHERLANDS Doxycyclin 50 Dopharma Doxycycline hyclate 500 mg/g Powder for oral solution Chickens(broiler) Calves pigs In drinking water 25 mg/kg X 3-5 days Meat and offal: 9 days Indications: Respiratory infections caused by Mycoplasma spp, E.coli, Haemophilus paragalinarum, Bordetella avium Enteritis caused by Clostridium perfringens and colinum

Greece Durden Trading Limited 12, Kennedy Av. Nicosia CYPRUS Doxycycline 150/Durden Doxycycline hydrocloride 150 mg/g Powder for oral solution Chickens(broiler) Non –egg laying chickens Calves pigs In drinking water 10 mg/kg X 3-5 days Meat and offal: 4 days Indications: Respiratory infections caused by Mycoplasma gallisepticum, E.coli, Haemophilus paragalinarum

Greece AFOI TETOROU ABE 10 km National road Athens-Lamia 14451, Metamorfosi GREECE Doxycycline 150/Afoi Tetorou Doxycycline hydrocloride 150 mg/g Powder for oral solution Chickens(broiler) Non –egg laying chickens Calves pigs In drinking water 10 mg/kg X 3-5 days Meat and offal:4 days Indications: Respiratory infections caused by Mycoplasma gallisepticum, E.coli, Haemophilus paragalinarum

Spain LAB. DR ESTEVE Avda Mare de Deu de Montserrat 221 08041 Barcelona SPAIN DOX ESTEVE Doxycycline hyclate 100 mg/g Water soluble powder Poultry Pigs Bovine Oral 3-5 days 20 mg / Kg/day Meat and offal: 9 days Indications: Infections caused by Mycoplasma spp (Micoplasmosis, CRD) or Pasteurella multocida (Pasteurellosis). Meat and offal: Poultry: 5 days Turkeys: 7 days colibacilosis, C.R.D., micoplasmosis.

Spain S.P. Veterinaria SA Crta. Reus Vinyols Km 4.1 Apartado 60 Riudoms 43330 (Tarragona) SPAIN DOXI 100 mg/ml POLVO ORAL Doxycycline hyclate 10 g/100 g Water soluble powder Poultry Turkeys Pigs Oral 3-5 days (Poultry and turkeys) 5 days (Pigs) 50 – 100 mg/l drinking water/day (poultry and turkey) 10 mg/kg/day (pigs) Meat and offal: Broilers: 5 days Turkeys: 7 days Pigs: 4 days

Spain FATRO URIACH VETERINARIA, S.L. Constitucion, 1 08960 Sant Just Desvern SPAIN DOXIDOL Doxycycline hyclate 10 g/100 g Water soluble powder Poultry Pigs Oral 3-5 days 7.5 – 15 mg/kg/day Meat and offal: 7 days Indications: Colibacilosis CRD

Spain DIVASA-FARMAVIC, S.A. CTRA. SANT HIPOLIT, KM. 71 08503 GURB – VIC SPAIN DOXIVET 20 Doxycycline hyclate 200 mg/ml Oral solution Poultry Pigs Oral 3-5 days 10 - 20 mg/Kg/day Meat and offal: 7 days Indications: Colibacilosis, CRD, Micoplasmosis

Spain MEVET, S. A. POLIGONO INDUSTRIAL EL SEGRE, PARCELA409-410 25191 Lérida SPAIN DOXICIVALL POLVO Doxycycline hyclate 500 mg/g Water soluble powder Poultry Pigs Oral 3-5 days 20 mg/kg/day Meat and offal: 4 days Indications: Colibacilosis, CRD, Micoplasmosis

Spain Laboratorios Hipra S.A. Avda La Selva 135 17170 Amer (Girona) SPAIN HIPRADOXI-S Doxycycline hyclate 100 mg/ml Oral solution Poultry Pigs Oral 3-5 days 50 – 100 mg/l drinking water/day Meat and offal: 5 days Indications: colibacilosis, C.R.D., micoplasmosis

Spain LAMONS, S.A. POL.IND. MECANOVA, NAVES 27-28 25191 LLEIDA SPAIN DOXICICLINA 10 % LAMONS Doxycycline hyclate 100 mg/ml Oral solution Poultry Pigs Oral 3-5 days 50 – 100 mg/l drinking water/day Meat and offal: 5 days Indications: colibacilosis, C.R.D., micoplasmosis

Spain Laboratorios Hipra S.A. Avda La Selva 135 17170 Amer (Girona) SPAIN HIPRADOXI-P Doxycycline hyclate 100 mg/g Water soluble powder Poultry Pigs Oral 3-5 days 20 mg/Kg/day Meat and offal: 5 days Indications: colibacilosis, C.R.D., and associated infections

Spain POLICHEM, S.A. Ctra. Reus-Cambrils, Km. 3 43206 Reus SPAIN DOXICHEM Doxycycline hyclate 500 mg/g Water soluble powder Poultry Oral 3-5 days 50 – 100 mg/l drinking water/day Meat and offal: 7 days Indications: colibacilosis, C.R.D., micoplasmosis

Spain SUPER'S DIANA, S.L Ctra. Barcelona - Ripoll, Km 17 08150 Parets del Valles SPAIN DOXBRON Doxycycline hyclate 500 mg/g Water soluble powder Poultry Oral 3-5 days 50 – 100 mg/l drinking water/day Meat and offal: 7 days Indications: colibacilosis, C.R.D., micoplasmosis

Spain COTECNICA -COOPERATIVA TECNICA AGROPECUARIA Ctra. N II KM 494,5 25250 Bellpuig (Lerida) SPAIN DOXICICLINA 500 USO VETERINARIO COTECNICA Doxycycline hyclate 500 mg/g Water soluble powder Poultry Oral 3-5 days 50 – 100 mg/l drinking water/day Meat and offal: 7 days Indications: colibacilosis, C.R.D., micoplasmosis

Spain CENAVISA, S.A. Camí Pedra Estela S/N 43205 Reus SPAIN LAFIDOX POLVO ORAL Doxycycline hyclate 500 mg/g Water soluble powder Poultry Oral 3-5 days 50 – 100 mg/l drinking water/day Meat and offal: 7 days Indications: colibacilosis, C.R.D., micoplasmosis

Spain LABORATORIOS SYVA, S.A. PARROCO PABLO DIEZ, 49-57 24010 TROBAJO DEL CAMINO SPAIN SYVADOX 10 % Doxycycline hyclate 100 mg/ml Oral solution Poultry Pigs Oral 3-5 days 50 – 100 mg/l drinking water/day Meat and offal: 7 days Indications: colibacilosis, C.R.D., micoplasmosis

Spain INVESA INTERNACIONAL, S.A. Esmeralda, 19 - 4o 08950 ESPLUGUES DE LLOBREGAT SPAIN DX-10 Doxycycline hyclate 100 mg/ml Oral solution Poultry Pigs Oral 3-5 days 50 – 100 mg/l drinking water/day Meat and offal: 7 days Indications: colibacilosis, C.R.D., micoplasmosis

Spain CENAVISA, S.A. Camí Pedra Estela S/N 43205 Reus SPAIN DOXICICLINA 500 GANADEXIL Doxycycline hyclate 500 mg/g Water soluble powder Poultry Turkeys Oral 3-5 days 50 – 100 mg/l drinking water/day Meat and offal: 7 days Indications: colibacilosis, C.R.D., micoplasmosis

Spain DIVASA-FARMAVIC, S.A. CTRA. SANT HIPOLIT, KM. 71 08503 GURB – VIC SPAIN DOXIVET 5 Doxycycline hyclate 50 mg/g Water soluble powder Poultry Turkeys Oral 3-5 days 50 – 100 mg/l drinking water/day Meat and offal: 7 days Indications: colibacilosis, C.R.D., micoplasmosis

Spain INDUSTRIAL VETERINARIA S.A. Esmeralda, 19 - 4o 08950 ESPLUGUES DE LLOBREGAT SPAIN DOXINYL Doxycycline hyclate 100 mg/ml Oral solution Poultry Pigs Oral 3-5 days 50 – 100 mg/l drinking water/day Meat and offal: 7 days Indications: colibacilosis, C.R.D., micoplasmosis

Spain JAER, S.A. Barcelona, 411 08620 San Vicens del Horts SPAIN MASTERMIX DOXICICLINA Doxycycline hyclate 50 mg/g Water soluble powder Poultry Turkeys Oral 3-5 days 50 – 100 mg/l drinking water/day Meat and offal: 7 days Indications: colibacilosis, C.R.D., micoplasmosis

Spain Laboratorios Karizoo S.A Polígono Industrial La Borda Mas Pujades 11-12 08140 Caldes de Montbui Barcelona SPAIN KARIDOX Doxycycline hyclate 100 mg/ml Oral solution Poultry Pig Oral 3-5 days 10 - 20 mg/Kg/day Meat and offal: 7 days Indications: C.R.D., micoplasmosis

Spain CHEMO IBERICA, S.A. Gran Via Carlos III, 98 7a Edificio Trade 08028 Barcelona SPAIN SOLDOXIN Doxycycline hyclate 100 mg/ml Oral solution Poultry Pig Oral 3-5 days 10 - 20 mg/Kg/day Meat and offal: 7 days Indications: C.R.D., micoplasmosis

Spain LABORATORIOS CALIER, S.A. BARCELONÉS, 26 08520 Les Franqueses del Valles SPAIN CALIERDOXINA 50 % P O Doxycycline hyclate 500 mg/g Water soluble powder Poultry Oral 5 days 20 mg/kg/day Meat and offal: 7 days Indications: C.R.D., micoplasmosis

Spain LABORATORIOS CALIER, S.A. BARCELONÉS, 26 08520 Les Franqueses del Valles SPAIN GANAMIX DOXICICLINA 50 % P O Doxycycline hyclate 500 mg/g Water soluble powder Poultry Oral 5 days 20 mg/kg/day Meat and offal: 7 days Indications: C.R.D., micoplasmosis

Spain S.P. Veterinaria SA Crta. Reus Vinyols Km 4.1 Apartado 60 Riudoms 43330 (Tarragona) SPAIN HIDRODOX 10 % Doxycycline hyclate 100 mg/ml Oral solution Poultry Pigs Oral 3-5 days 50 – 100 mg/l drinking water/day Meat and offal: 7 days Indications: colibacilosis, C.R.D., micoplasmosis

Spain VIRBAC ESPAÑA, S.A. Angel Guimera, 179-181 08950 Esplugues de Llobregat SPAIN PULMODOX P.O.S. Doxycycline hyclate 500 mg/g Water soluble powder Poultry Oral 3-5 days 50 – 100 mg/l drinking water/day Meat and offal: 7 days Indications: C.R.D., micoplasmosis

Spain Huvepharma N.V. Uitbreidingstraat 80 2600 Antwerpen BELGIUM DILUDOX Doxycycline hyclate 500 mg/g doxycycline hyclate Powder for oral solution Chickens (broilers) & Pigs (fattening pigs) Oral (drinking water) 20 mg doxycycline (hyclate)/kg x 3-5 days Meat and offal: Chickens: 6 days Do not use in laying birds producing eggs for human consumption Indications: Chickens (broilers): Prevention and treatment of Chronic Respiratory Disease (CRD) caused by Mycoplasma gallisepticum.

Spain LABORATORIOS CALIER, S.A. BARCELONÉS, 26 08520 Les Franqueses del Valles SPAIN DOXICICLINA CALIER 500 mg/g Doxycycline hyclate 500 mg/g Water soluble powder Poultry Pigs Oral 3-5 days 20 mg/kg/day Meat and offal: 6 days Indications: Prevention and treatment of Chronic Respiratory Disease (CRD) caused by Mycoplasma gallisepticum

Spain LABORATORIOS MAYMO, S.A. Via Augusta, 302 08017 Barcelona SPAIN MAYDOX PS Doxycycline hydrocloride 50 mg/g Water soluble powder Poultry Turkeys Oral 3-5 days 50 – 100 mg/l drinking water/day Meat and offal: 7 days Indications: colibacilosis, C.R.D., micoplasmosis

France COOPHAVET Saint Herblon 44150 Ancenis FRANCE RONAXAN P.S. 5 % Doxycycline hyclate 50 mg/g Water soluble powder Turkey Porcine Broilers Calves Prevention 1 - 3 days Curative treatment: 3 - 5 days 10 mg/kg/day Meat and offal: Turkey: 6 days Broilers: 4 days Indications: Broilers and turkey: Preventive and treatment of infections in respiratory system

France FRANVET ZI d'Etriche-Route d'Avire BP 103 49500 Segré Cedex FRANCE DOXY 5 FRANVET Doxycycline hyclate 50 mg/g Water soluble powder Turkey, Porcine Hens Calves Prevention 1 - 3 days Curative treatment: 3 - 5 days 10 mg/kg/day Meat and offal: Turkey: 6 days Hens: 4 days Indications: Prevention and treatment of infections in respiratory system

France VIRBAC S.A. 1ère avenue - 2065 m - L.I.D. 06516 CARROS FRANCE PULMODOX P.O.S. 5 % Doxycycline hyclate 50 mg/g Water soluble powder Porcine Calves Poultry Prevention 1 - 3 days Curative treatment: 3 - 5 days 10 mg/kg/day Meat and offal: Turkey: 6 days Hens: 4 days Indications: Prevention and treatment of infections in respiratory system

France Sogeval Laboratoires 200 route De Mayenne 53022 Laval Cedex FRANCE DOXYVAL 5 % Doxycycline hyclate 50 mg/g Water soluble powder Turkey Porcine Broilers Calves Prevention 1 - 3 days Curative treatment: 3 - 5 days 10 mg/kg/day Meat and offal: Turkey: 6 days Hens: 4 days Indications: Prevention and treatment of infections in respiratory system

France Laboratoires Biove 3 rue de Lorraine 62510 Arques FRANCE ACTI DOXY 5 Doxycycline hyclate 50 mg/g Water soluble powder Dindon Porcine Broilers Calves Prevention 1 - 3 days Curative treatment: 3 - 5 days 10 mg/kg/day Meat and offal: Turkey: 6 days Hens: 4 days Indications: Prevention and treatment of infections in respiratory system

France Ceva Sante Animale France La Balastiere 33501 Libourne Cedex FRANCE DOXYVIT Doxycycline hyclate 50 mg/g Water soluble powder Turkeys Porcine Broilers Calves Prevention 1 - 3 days Curative treatment: 3 - 5 days 10 mg/kg/day Meat and offal: Turkey: 6 days Hens: 4 days Indications: Prevention and treatment of infections in respiratory system

France Noe 10 rue Clement Ader ZA Le Patis 78120 Rambouillet FRANCE COMPOMIX V DOXYCYCLINE Doxycycline hyclate 50 mg/g Water soluble powder Dindon Porcine Broilers Calves Prevention 1 - 3 days Curative treatment: 3 - 5 days 10 mg/kg/day Meat and offal: Turkey: 6 days Hens: 4 days Indications: Prevention and treatment of infections in respiratory system

France CHEMO IBERICA, S.A. Gran Via Carlos III, 98 7a Edificio Trade 08028 Barcelona SPAIN SOLDOXIN 100 MG/ML SOLUTION BUVABLE POUR POULES POULETS ET PORCINES Doxycycline hyclate 100 mg/ml Oral solution Porcine Hens Broilers CHICKEN (broilers): 10 - 20 mg of doxycycline / kg bw / day 3 - 5 days Indications: CHICKENS (BROILERS) Prevention and treatment of chronic respiratory disease (CRD) and mycoplasmosis caused by microorganisms sensitive to doxycycline.

France Laborartorios Karizoo S.A. Pol.Ind. La Borda c/Mas Pujades 11-12 Caldes de Montbui 08140 SPAIN DOXYSOL 10 % Doxycycline hyclate 100 mg/ml Oral solution Porcine Hens Broilers CHICKEN (broilers): 10 - 20 mg of doxycycline / kg bw / day 3 - 5 days Indications: CHICKENS (BROILERS). Prevention and treatment of chronic respiratory disease (CRD) and mycoplasmosis caused by microorganisms sensitive to doxycycline.

France Huvepharma N.V. Uitbreidingstraat 80 2600 Antwerpen BELGIUM HYDRODOXX 500 MG/G poudre pour administration dans l'eau de boisson pour poulets et porcs Doxycycline hyclate 500 mg/g doxycycline hyclate Powder for oral solution Chickens (broilers) & Pigs (fattening pigs) Oral (drinking water) 20 mg doxycycline (hyclate)/kg x 3-5 days Meat and offal: Chickens: 6 days Do not use in laying birds producing eggs for human consumption Indications: Chickens (broilers): Prevention and treatment of Chronic Respiratory Disease (CRD) caused by Mycoplasma gallisepticum.

France LABORATORIOS CALIER, S.A. BARCELONÉS, 26 08520 Les Franqueses del Valles SPAIN DOXYCYCLINE CALIER 500 MG/G poudre pour administration dans l'eau de boisson pour poulets et porcins Doxycycline hyclate 500 mg/g Water soluble powder Poultry Pigs Oral 3-5 days 20 mg/kg/day Meat and offal: 6 days Indications: Prevention and treatment of Chronic Respiratory Disease (CRD) caused by Mycoplasma gallisepticum

Hungary COOPHAVET Saint Herblon 44150 Ancenis FRANCE Ronaxan P.S. 5 % oldható por Doxycycline hyclate 5 g/100 g Powder for oral solution Chicken Chicken younger than 2 weeks: 1 g powder/1 litre of drinking water/day. Chicken older than 2 weeks: 2 g powder/1 litre of drinking water. 10 mg doxycycline/kg bw/day, for 3-5 days. Meat and offal: 4 days Indications: For the treatment of CRD and Mycoplasma diseases, and other infections

Hungary DOPHARMA B.V. Zalmweg 24, P.O. BOX 205 4940 AE Raamsdonksveer THE NETHERLANDS Doxycycline 50 % WSP Doxycycline hyclate 500 mg/g Powder for oral solution Chicken 500 g product dissolved in 1 000 litre of drinking water. 25 mg doxycycline/kg bw/day, for 3-5 days. Meat and offal: 4 days Indications: For the treatment and control of chicken respiratory diseases

Hungary Kon-Pharma GmbH. 30625 Hannover GERMANY Doxy 50 % por belsőleges oldathoz Doxycycline hyclate 500 mg/g Powder for oral solution Chicken, turkey Chicken: 500 mg product dissolved in 1 litre of drinking water. Turkey: 400 mg product/1 litre of drinking water 30 mg doxycycline/kg bw/day, for 5 days. Meat and offal: Chicken and turkey: 11 days.

Hungary V.M.D. Állatgyógyászati Kft. 1093 Budapest HUNGARY Doxyveto-50 Doxycycline hyclate 500 mg/g Powder for oral solution Chicken Continuous treatment: 0,2 g product/1 litre of drinking water. Pulse treatment: calculated amount of the product should be dissolved in the drinking water consumed during 8 hours. 10 mg doxycycline/kg bw/day, for 5 days. Meat and offal: 10 days Indications: For the treatment of CRD and pasteurellosis; synovitis in turkey.

Hungary Novartis Animal Health d.o.o. Verovskava 57 1000 Ljubljana SLOVENIA Doxyril 50 % por belsőleges oldathoz Doxycycline hyclate 500 mg/g Powder for oral solution Chicken 5 g product/100 kg bw/day, dissolved in the drinking water. 25 mg doxycycline/kg bw/day, for 3-5 days. Meat and offal: 6 days Indications: For the treatment of CRD, pasteurellosis, colibacillosis, Haemophilus and Clostridium infections

Hungary Animal-Med Kft. 1029 Budapest HUNGARY Anidox 10 % por belsőleges oldathoz Doxycycline hyclate 100 mg/g Powder for oral solution Chicken 1 000 g product dissolved in 1 000 litre of drinking water. 10 mg doxycycline/kg bw/day, for 5 days. Meat and offal: 12 days Indications: For the treatment of mycoplasmosis, pasteurellosis, colibacillosis.

Hungary Animal-Med Kft. 1029 Budapest HUNGARY Anidox 100 % por belsőleges oldathoz Doxycycline hyclate 1 000 mg/g Powder for oral solution Chicken 100 g product dissolved in 1 000 litre of drinking water. 10 mg doxycycline/kg bw/day, for 5 days. Meat and offal: 12 days Indications: For the treatment of infections caused by: Mycoplasma gallisepticum, E. coli, Bordetella avium, Haemophilus paragallinarum and Pasteurella multocida

Hungary Lavet Pharmaceuticals Ltd., 1161 Budapest Ottó u. 14, HUNGARY Doxyprim 40 % vízoldékony pulvis Doxycycline hyclate 400 mg/g Powder for oral solution Chicken, turkey Continuous treatment: 1 g product/3-6 litre of drinking water. Pulse treatment: calculated amount of the product should be dissolved in the drinking water consumed during 4-8 hours. 10-20 mg/doxycycline/kg bw/day, for 3-5 days. Meat and offal: 4 days Indications: For the treatment of infections caused by: Mycoplasma gallisepticum, E. coli, Bordetella avium, Haemophilus paragallinarum and Pasteurella multocida

Hungary CHEMIFARMA S.p.A Via Don Eugenio Servadei 16 47100 Forli ITALY Doxifarm 50 % WSP Doxycycline hyclate 500 mg/g Powder for oral solution Chicken 40 g product/100 kg bw/100 litre of drinking water. 20 mg doxycycline/kg bw/day, for 5 days. Meat and offal: 5 days Indications: For the treatment of CRD, mycoplasmosis, synovitis, colibacillosis, ileitis (necroric and ulcerosus), haemophilus-infection.

Hungary VIRBAC S.A. 1ère avenue - 2065 m - L.I.D. 06516 CARROS FRANCE Pulmodox 50 % WSP Doxycycline hyclate 500 mg/g Powder for oral solution Chicken 500 g product dissolved in 1 000 litre of drinking water. 25 mg doxycycline/kg bw/day, for 3-5 days. Meat and offal: 4 days Indications: For the treatment of CRD and other respiratory diseases, caused by: Mycoplasma spp., Pasteurella spp., E. coli, and Chlamydia psittaci.

Hungary Phylaxia Pharma Zrt. 8000 Székesfehérvár HUNGARY Doxyphyl SP Doxycycline hyclate 300 mg/g Powder for oral solution chicken, turkey 40 g product/1 200 kg bw/day, calculated amount of the product should be dissolved in the drinking water consumed during 3 hours. 10 mg doxycycline/kg bw/day, for 3-5 days. Meat and offal: chicken: 7 days, turkey: 10 days. Indications: For the treatment of respiratory infections caused by Mycoplasma spp., E. coli, Haemophilus paragallinarum, Bordetella avium, and ileitis caused by Clostridium perfringens and Cl. colinum.

Hungary Eurovet Animal Health B.V. Handelsveg 25 PO Box 179 5530 AD Bladel THE NETHERLANDS Soludox 50 % pulvis Doxycycline hyclate 500 mg/g Powder for oral solution Chicken Dissolved in the drinking water. 10 mg/kg bw and 20 mg/kg bw/day, for 4 days. Meat and offal: chicken treated with 10 mg/kg bw: 5 days, chicken treated with 20 mg/kg bw: 12 days. Indications: For the treatment of respiratory and other diseases caused by doxycycline-sensitive bacteria.

Hungary CHEMO IBERICA, S.A. Gran Via Carlos III, 98 7a Edificio Trade 08028 Barcelona SPAIN Oridox 100 mg/ml belsőleges oldat Doxycycline hyclate 100 mg/ml Concentrate for oral solution Chicken 100 mg/ml oral concentrate dissolving in the drinking water. 10-20 mg/doxycycline/kg bw/day, for 3-5 days. Meat and offal: 7 days Indications: For the treatment of respiratory and other diseases caused by doxycycline-sensitive bacteria.

Hungary Laboratorios Karizoo S.A Polígono Industrial La Borda Mas Pujades 11-12 08140 Caldes de Montbui Barcelona SPAIN Karidox 100 mng/ml belsőleges oldat Doxycycline hyclate 100 mg/ml Concentrate for oral solution Chicken 100 mg/ml oral concentrate dissolving in the drinking water. 10-20 mg/doxycycline/kg bw/day, for 3-5 days. Meat and offal: 7 days Indications: For the treatment and prevention of CRD or other Mycoplasma diseases

Hungary CENAVISA, S.A. Camí Pedra Estela S/N 43205 Reus SPAIN Doxycen belsőleges oldat Doxycycline hyclate 200 mg/ml Concentrate for oral solution Chicken 1 ml/20 kg bw/day dissolved in the drinking water. 10 mg doxycycline/kg bw/day, for 5 days. Meat and offal: 5 days Indications: For the treatment of CRD, mycoplasmosis and colibacillosis.

Hungary Lavet Pharmaceuticals Ltd., 1161 Budapest Ottó u. 14, HUNGARY Doxyvit 100 WSP Doxycycline hydrocloride 100 mg/g Powder for oral solution Chicken, turkey, goose Continuous treatment: 1 g product/1 litre of drinking water. Pulse treatment: calculated amount of the product should be dissolved in the drinking water consumed during 6-8 hours. 10 mg/doxycycline/kg bw/day, for 3-5 days. Meat and offal: Chicken, turkey, goose 7 days Indications: For the treatment of respiratory and enteric diseases in broiler chickens

Hungary Industria Italiana Integratori TREI S.p.A. Viale Corassori 62 41100 Modena ITALY Doxipan 20 WSP Doxycycline hydrocloride 200 mg/g Powder for oral solution Chicken 5-7.5 g product dissolving in 10 litre of drinking water. 10-15 mg/doxycycline/kg bw/day, for 3-5 days. Meat and offal: 5 days Indications: For the treatment of CRD, mycoplasmosis, synovitis, colibacillosis, ileitis (necroric and ulcerosus), haemophilus-infection.

Hungary Laboratorios Hipra S.A. Avda La Selva 135 17170 Amer (Girona) SPAIN Hipradoxi-S oral solutio Doxycycline hydrocloride 100 mg/ml Concentrate for oral solution Chicken 100 mg/ml oral concentrate dissolving in 1 litre of drinking water. 10 mg doxycycline/kg bw/day, for 5 days. Meat and offal: 5 days Indications: For the treatment and prevention of CRD or other Mycoplasma diseases

Ireland S.P. Veterinaria SA Crta. Reus Vinyols Km 4.1 Apartado 60 Riudoms 43330 (Tarragona) SPAIN DOXIVEX 10 % Concentrate for oral solution. Doxycycline hyclate 100 mg/ml Concentrate for oral solution Chickens (broilers) and Pigs For oral administration via the drinking water. for 3-5 days Chickens (broilers): 50 - 100 mg Doxycycline / litre of drinking water / day (equivalent to 0.5 - 1.0 ml DOXIVEX 10 % / litre of drinking water / day) for 3-5 days Meat & offal: 7 days. Not permitted for use in laying birds producing eggs for human consumption Indications: Treatment of colibacillosis, chronic respiratory disease (CRD) and mycoplasmosis caused by microorganisms sensitive to doxycycline

Ireland Huvepharma N.V. Uitbreidingstraat 80 2600 Antwerpen BELGIUM Aquadoxx 500 mg/g water-soluble powder Doxycycline hyclate 500 mg/g doxycycline hyclate Powder for oral solution Chickens (broilers) & Pigs (fattening pigs) Oral (drinking water) 20 mg doxycycline (hyclate)/kg x 3-5 days Meat and offal: Chickens: 6 days Do not use in laying birds producing eggs for human consumption Indications: Chickens (broilers): Prevention and treatment of Chronic Respiratory Disease (CRD) caused by Mycoplasma gallisepticum.

Italy CEVA VETEM S.P.A. Via Colleoni n.15 20041 Agrate Brianza (Milano) ITALY DOXICICLINA 20 % CEVA VETEM Doxycycline hyclate Doxycycline 200 g. per 1 kg. of product Water soluble powder broiler, turkey drinking water Broiler, Turkey: 1 g / 10 kg b.w per 5 days. Meat and offal: broiler: 7 days turkey: 8 days Indications: Broiler: Treatment of chronic respiratory disease Turkey: Treatment of infective synusitis

Italy CHEMIFARMA S.p.A Via Don Eugenio Servadei 16 47100 Forli ITALY DOXICICLINA 50 % CHEMIFARMA Doxycycline hyclate Doxycycline 500 g. per 1 kg. of product Water soluble powder broiler, swine drinking water Broiler: 20 mg of doxycycline / per 1 kg b.w.(per 3 - 5 days) Swine: 20 mg of doxycycline / per 1 kg b.w per 3 - 5 days Meat and offal: broiler: 6 days Do not use in hens producing eggs for human consumption. swine: 5 days Indications: Broiler: Chronic respiratory disease caused by: Pasteurella soo, Mycoplasma spp, Haemophilus gallinarum, Bordetella avium, ans Clamidia psittaci.

Italy SINTOFARM S.P.A. Via Togliatti n.5 42016 Guastalla (Reggio Emilia) ITALY DOXIFARM 50 % Doxycycline hyclate Doxycycline hyclate 500 mg. (equivalent to 433,3 mg of Doxiclina) per 1 g. of product Water soluble powder broiler, swine drinking water Broiler: 25 mg of doxycycline hyclate/per 1 kg b.w.(per 3 - 5 days) Swine: 20 mg of doxycycline hyclate/per 1 kg b.w per 5 days Meat and offal: broiler: 6 days Do not use in hens producing eggs for human consumption. swine: 4 days Indications: Broiler: Treatment and control of respiratory disease caused by Mycoplasma spp, Haemophilus paragallinarum, Escherichia coli. Enteritis caused by Clostridium perfringens and Clostridium colinum

Italy INDUSTRIA ITAILIANA INTEGRATORI TREI SpA Via Affarosa n.4 42010 Rio Saliceto (Reggio Emilia) ITALY DOXIPAN 54 Doxycycline hyclate Doxycycline 500 g. per 1 kg. of product Water soluble powder broiler, turkey, swine drinking water Broiler: 10 mg of doxycycline / 1 kg b.w. Turkey: 20 mg of doxycycline / 1 kg b.w. Swine: 10 mg of doxycycline / 1 kg b.w per 5 days Meat and offal: broiler: 3 days Do not use in hens producing eggs for human consumption. turkey: 10 days swine: 4 days Indications: Broiler:Chronic respiratory disease. Turkey:Respiratory and joints syndroms caused by Mycoplasms and/or Staphilococcus

Italy INTERVET ITALIA S.R.L. Via W. Tobagi n.7 20068 Peschiera Borromeo (Milano) ITALY NAXOCET Doxycycline hyclate Doxycycline hyclate 500 mg. per 1 g. of product Water soluble powder broiler drinking water Broiler: 20 mg of doxyclyne hyclate/1 kg b.w. per 5 days. Meat and offal: broiler: 8 days Do not use in hens producing eggs for human consumption. Indications: Chronic respiratory disease caused by Mycoplasma spp.

Lithuania DOPHARMA B.V. Zalmweg 24, P.O. BOX 205 4940 AE Raamsdonksveer THE NETHERLANDS DOXYCYCLINE 50 %, geriamieji milteliai Doxycycline hyclate 500 mg/g Oral powder Calves, pigs and poultry. 4–7 days with drinking water Poultry: 40 mg per 1 kg of body weight, or 200–400 g per 1 000 litres of drinking water, during 4–7 days. Meat and offal: Poultry – 4 days. Do not use in animals producing eggs for human consumption. Indications: for the treatment of poultry: ornythosis, caused by Clamydia psittaci, colibacteriosis caused by E. coli, CRD caused by Mycoplasma gallisepticum

Lithuania Lavet Pharmaceuticals Ltd., 1161 Budapest Ottó u. 14, HUNGARY DOXYPRIM 40 % geriamieji milteliai Doxycycline hyclate 400 mg/g Oral powder Chickens, turkeys and pigs. Should be administered for a period of 5 days in chicken and turkeys together with drinking water. Chicken and turkeys: 10–20 mg doxycycline hyclate per 1 kg of body weight daily, administrated pulse dosed when the daily requirement is given in limited quantity of water to be consumed by the birds within 4–8 hours or supplied continuously as 67–133 mg ml Doxycycline hyclate per 1 litre of drinking water. Meat and offal: Edible tissues of chickens and turkeys – 4 days. Indications: In chickens and turkeys indications include: chronicle respiratoric diseases (Mycoplasma gallisepticum, E. coli), airsacculitis (Mycoplasma meleagridis), infectious synovitis (Mycoplasma synoviae), colibacillosis (E. coli), fowl cholera (Pasteurella multocida), turkey bordetellosis (Bordetella avium), infectious coryza (Haemophilus paragallinarum), necrotic enteritis (Clostridium perfringens), chlamydiosis (Chlamydia psittaci).

Lithuania Eurovet Animal Health B.V. Handelsveg 25 PO Box 179 5530 AD Bladel THE NETHERLANDS SOLUDOX 50 %, geriamieji milteliai Doxycycline hyclate 500 mg/g Oral powder Pigs and chickens. Should be administered orally with drinking water for a period of 4 days. Chickens: 10* mg doxycycline hyclate per 1 kg of body weight daily for 4 days; 20* mg doxycycline hyclate per 1 kg of body weight daily for 4 days. * The highest dose is recommended in case of infections caused by strains which are moderately susceptible (MIC up to 2 µg/ml), whilst the lowest dosage maybe used for (highly) susceptible strains (MIC up to 0.5–1.0 µg/ml) Indications: For the treatment of infections caused by micro-organisms susceptible to doxycycline, such as Pasteurella multocida and Ornithobacterium rhinotracheale in chickens.

The Netherlands DOPHARMA B.V. Zalmweg 24, P.O. BOX 205 4940 AE Raamsdonksveer THE NETHERLANDS Doxycycline-hyclaat 50 % Doxycycline hyclate Per gram powder: 500 mg doxycycline hyclate. Powder for oral solution Calves, non-egg laying chickens and turkeys. Non-egg laying chickens and turkeys: oral via drinking water. bodyweight per day for 4-7 days. Non-egg laying chickens and turkeys: 20 mg doxycycline hyclate per kg Turkeys - meat: 28 days. Non-egg laying chickens - meat: 14 days. Indications: Turkeys: — Ornithosis caused by Chlamydia psittaci — Colibacillosis caused by E. coli — CRD caused by Mycoplasma gallisepticum Non-egg laying chikens Colibacillosis caused by E. coli

The Netherlands Dutch Farm Veterinary Pharmaceuticals B.V. Veemweg 1 3771 MT Barneveld THE NETHERLANDS Doxycycline 20 % W.O. Doxycycline hyclate Per gram powder: 200 mg doxycycline hyclate Powder for oral solution Non-egg laying chickens Oral via drinking water. for 3 days 10 mg doxycycline hyclate per kg bodyweight per day for 3 days Meat: 7 days. Indication non-egg laying chickens: — Polyarthritis caused by Mycoplasma synoviae; — CRD, amongst others caused by Mycoplasma gallisepticum; — Colibacillosis caused by Escherichia coli

The Netherlands DOPHARMA B.V. Zalmweg 24, P.O. BOX 205 4940 AE Raamsdonksveer THE NETHERLANDS Doxycycline-hyclaat 20 % Doxycycline hyclate Per gram powder: 200 mg doxycycline hyclate. Powder for oral solution Calves, pigs, chickens and turkeys. Chickens and turkeys: oral via drinking water for 4-7 days. Chickens and turkeys: 20 mg doxycycline hyclate per kg bodyweight Turkeys - meat: 28 days. Chickens - meat: 14 days, eggs: 10 days. Indication turkeys: — Ornithosis caused by Chlamydia psittaci — Colibacillosis caused by E. coli — CRD caused by Mycoplasma gallisepticumIndication Indication chickens: — Colibacillosis caused by E. coli — CRD caused by Mycoplasma gallisepticum

The netherlands Dutch Farm International B.V. Nieuw Walden 112 1394 PE Nederhorst den Berg THE NETHERLANDS Doxycycline 20 % W.O. Doxycycline hyclate Per gram powder: 200 mg doxycycline hyclate. Powder for oral solution Non-egg laying chickens (broilers). Oral via drinking water. 10 mg doxycycline hyclate per kg bodyweight per day for 3 days. Meat: 7 days. Do not administer to chickens producing eggs for human consumption. Indication non-egg laying chickens: — Polyarthritis caused by Mycoplasma synoviae; — CRD, amongst others caused by Mycoplasma gallisepticum; — Colibacillosis caused by Escherichia coli.

The Netherlands DOPHARMA B.V. Zalmweg 24, P.O. BOX 205 4940 AE Raamsdonksveer THE NETHERLANDS Doxycycline-hyclaat 50 % Doxycycline hyclate Per gram powder: 500 mg doxycycline hyclate. Powder for oral solution Calves, pigs, non-egg laying chickens. Non-egg laying chickens: oral via drinking water. for 4-5 days. Non-egg laying chickens: 20 mg doxycycline hyclate per kg bodyweight per day for 4-5 days. Non-egg laying chickens - meat: 14 days. Indication non-egg laying chickens: — Colibacillosis caused by E. coli — CRD caused by Mycoplasma gallisepticum

The Netherlands DOPHARMA B.V. Zalmweg 24, P.O. BOX 205 4940 AE Raamsdonksveer THE NETHERLANDS Doxycycline 50 % WSP Doxycycline hyclate Per gram powder: 500 mg doxycycline hyclate. Powder for oral solution Non-egg laying chickens. Non-egg laying chickens: oral via drinking water. Non-egg laying chickens: 25 mg doxycycline hyclate per kg bodyweight per day for 3-5 days. Non-egg laying chickens - meat: 6 days. Indication non-egg laying chickens: — Respiratory infections caused by Mycoplasma spp (M. gallisepticum, M.synoviae en M. meleagridis), E. coli and Haemophilus paragallinarum; — Enteritis caused by Clostridium perfringens en Clostridium colinum.

The Netherlands Interchemie Werken De Adelaar BV Hosterweg 26a 5811 Ccastenray THE NETHERLANDS Doxy WS Doxycycline hyclate Per gram powder: 200 mg doxycycline hyclate. Powder for oral solution Non-egg laying chickens (broilers). Oral via drinking water. 10 mg doxycycline hyclate per kg bodyweight per day for 3 days. Meat: 7 days. Indication non-egg laying chickens: — Polyarthritis caused by Mycoplasma synoviae; — CRD, amongst others caused by Mycoplasma gallisepticum; — Colibacillosis caused by Escherichia coli.

The Netherlands Eurovet Animal Health B.V. Handelsveg 25 PO Box 179 5530 AD Bladel THE NETHERLANDS Soludox 50 % Doxycycline hyclate Per gram powder: 500 mg doxycycline hyclate. Powder for oral solution Pigs and non-egg laying chickens. Non-egg laying chickens: oral via drinking water. Non-egg laying chickens: - Pasteurellosis caused by Pasteurella multocida: 10 mg doxycycline hyclate per kg bodyweight per day for 3-4 days.infections caused by Ornithobacterium rhinotracheale (ORT): 20 mg doxycycline hyclate per kg bodyweight per day for 3-4 days Non-egg laying chickens: - Pasteurellosis – meat: 5 days.- ORT – meat: 12 days. Do not administer to chickens producing eggs for human consumption

The Netherlands Eurovet Animal Health B.V. Handelsveg 25 PO Box 179 5530 AD Bladel THE NETHERLANDS Doxyfar 50 % Doxycycline hyclate Per gram powder: 500 mg doxycycline hyclate. Powder for oral solution Pigs and non-egg laying chickens. Non-egg laying chickens: oral via drinking water. Non-egg laying chickens: Pasteurellosis caused by Pasteurella multocida: 10 mg doxycycline hyclate per kg bodyweight per day for 3-4 - Respiratory infections caused by Ornithobacterium rhinotracheale (ORT): 20 mg doxycycline hyclate per kg bodyweight per day for 3-4 days Non-egg laying chickens: — Pasteurellosis – meat: 5 days. — ORT – meat: 12 days. Do not administer to chickens producing eggs for human consumption.

The Netherlands Kepro B.V. Maagdenburgstraat 38 7421 ZE Deventer THE NETHERLANDS Doxy 200 W.S.P. Doxycycline hyclate Per gram powder: 200 mg doxycycline hyclate. Powder for oral solution Non-egg laying chickens (broilers). Oral via drinking water. 10 mg doxycycline hyclate per kg bodyweight per day for 3 days. Meat: 7 days. Do not administer to chickens producing eggs for human consumption. Indication: — Polyarthritis caused by Mycoplasma synoviae; — CRD, amongst others caused by Mycoplasma gallisepticum; — Colibacillosis caused by Escherichia coli.

The Netherlands Eurovet Animal Health B.V. Handelsveg 25 PO Box 179 5530 AD Bladel THE NETHERLANDS Soludox 50 % Doxycycline hyclate Per gram powder: 500 mg doxycycline hyclate. Powder for oral solution Pigs and non-egg laying chickens. Non-egg laying chickens: oral via drinking water. Non-egg laying chickens: 10 mg doxycycline hyclate per kg bodyweight per day for 3-4 days. Non-egg laying chickens – meat: 5 days. Indication: Pasteurellosis caused by Pasteurella multocida

The Netherlands Laboratorios Karizoo S.A Polígono Industrial La Borda Mas Pujades 11-12 08140 Caldes de Montbui Barcelona SPAIN Karidox 10 % Oral Solution Doxycycline hyclate Per ml: 100 mg doxycycline (as hyclate). Oral solution Pigs and chickens (broilers). Chickens (broilers): oral via drinking water. Chickens (broilers): 10-20 mg doxycycline per kg bodyweight per day for 3-5 days Chickens (broilers) - meat: 7 days. Indication: Prevention and treatment of CRD and mycoplasmosis caused by microorganisms sensitive to doxycycline.

The Netherlands Huvepharma, Uitbreidingstraat 80 2600 Antwerpen BELGIUM HydroDoxx 500 mg/g Doxycycline hyclate Per g: 500 mg doxycycline hyclate. Powder for oral solution Pigs and chickens (broilers). Chickens (broilers): oral via drinking water. Chickens (broilers): 20 mg doxycycline per kg bodyweight per day for 3-5 days Chickens (broilers) - meat: 6 days. Do not administer to chickens producing eggs for human consumption.

The Netherlands CHEMO IBERICA, S.A. Gran Via Carlos III, 98 7a Edificio Trade 08028 Barcelona SPAIN Soldoxin Doxycycline hyclate Per ml: 100 mg doxycycline (as hyclate). Oral solution Pigs and chickens (broilers). Chickens (broilers): oral via drinking water. Chickens (broilers): 10-20 mg doxycycline per kg bodyweight per day for 3-5 days Chickens (broilers) - meat: 7 days. Do not administer to chickens producing eggs for human consumption. Indication: Prevention and treatment of CRD and mycoplasmosis caused by microorganisms sensitive to doxycycline.

Poland DOPHARMA B.V. Zalmweg 24, P.O. BOX 205 4940 AE Raamsdonksveer THE NETHERLANDS Doxymed 50 Doxycycline hyclate 500 mg/g powder for oral solution chickens 250-500 ml product/1 000 liter of drinking water 25 mg doxycyclini hyclate / kg bw/day for 3-5 days Meat and offal: 4 days. Not for use in laying hens.

Poland Eurovet Animal Health B.V. Handelsveg 25 PO Box 179 5530 AD Bladel THE NETHERLANDS Soludox 50 % Doxycycline hyclate 500 mg/g Oral powder chickens 2 g product/100 kg bw/day in case of Pasteurellosis or 4 g product / 100 kg bw/day in case of Ornithrobacterium rhinotracheale infection. 10 mg doxycycliny hyclate/kg bw/day in case of Pasteurellosis or 20 mg doxycyclini hyclate/kg bw/day in case of Ornithrobacterium rhinotracheale infection for 3-4 days Meat and offal: 5 days in case of Pasteurellosis. 12 days in case of Ornithrobacterium rhinotracheale infection. Not for use in laying hens.

Poland Laboratorios Hipra S.A. Avda La Selva 135 17170 Amer (Girona) SPAIN Hipradoxi-S Doxycycline hyclate 100 mg/ml Oral solution chickens 0,5-1,0 ml product/1 liter of drinking water 50-100 mg doxycyclini hyclate/1 liter of drinking water for 3-5 days Meat and offal: 5 days. Not for use in laying hens.

Poland Oropharma n.v. Dijkstraat 30 9140 Temse BELGIUM Ornicure Doxycycline hyclate 300 mg/4 g Oral powder pigeon, parrot pigeon: 4g prodyct/2 liters of drinking water, parrot: 4 g product/0,5 liter 15 mg/kg bw./ day for 5 days, in case of parrot desease or clinical ornitosis for 3-4 weeks Not for use in pigeons for human consumption.

Poland Novartis Animal Health d.o.o. Verovskava 57 1000 Ljubljana SLOVENIA Doxiryl 50 % Doxycycline hyclate 500 mg/g powder for oral solution chicken (broiler) 25 mg doxycyclini hyclate / kg bw/day 25 mg doxycyclini hyclate / kg bw/day for 3-5 days Meat and offal: 4 days. Not for use in laying hens.

Poland S.P. Veterinaria SA Crta. Reus Vinyols Km 4.1 Apartado 60 Riudoms 43330 (Tarragona) SPAIN Doxivex 10 % Doxycycline hyclate 100 mg/ml Concentrate for oral solution chicken (broiler) 05-1,0 ml product/1 liter of drinking water 50-100 mg doxycyclini hyclas/1 liter of drinking water/day for 3-5 days Meat and offal: 7 days. Not for use in laying hens.

Poland CHEMO IBERICA, S.A. Gran Via Carlos III, 98 7a Edificio Trade 08028 Barcelona SPAIN Oridox Doxycycline hyclate 100 mg/ml Oral solution chicken (broiler) 05-1,0 ml product/1 liter of drinking water 10-20 mg doxycyclini hyclas/kg bw/day for 3-5 days Meat and offal: 7 days. Not for use in laying hens.

Poland Laboratorios Karizoo S.A Polígono Industrial La Borda Mas Pujades 11-12 08140 Caldes de Montbui Barcelona SPAIN Karidox Doxycycline hyclate 100 mg/ml Oral solution chicken (broiler) 05-1,0 ml product/1 liter of drinking water 10 -20 mg doxycyclini hyclas/kg bw/day for 3-5 days Meat and offal: 7 days. Not for use in laying hens.

Poland Drwalewskie Zakłady Przemysłu Bioweterynaryjnego S.A. Grójecka 6 05-651 Drwalew POLAND Doxymina 20 % Doxycycline hyclate 200 mg/g Oral powder chicken 25-50 g product/1 liter of drinking water 10 mg doxycyclini hyclate/kg bw/day, for 3-5 days Meat and offal: 7 days. Not for use in laying hens.

Poland V.M.D.n.v./ s.a. Hoge Muew 900 2370 Arendonk BELGIUM Doxycycline hyclate 50 % Doxycycline hyclate 500 mg powder for oral solution chicken 25 mg doxycyclini hyclate / kg bw/day 25 mg doxycyclini hyclate / kg bw/day for 3-5 days Meat and offal: 5 days. Not for use in laying hens.

Poland INDUSTRIAL VETERINARIA S.A. Esmeralda, 19 - 4o 08950 ESPLUGUES DE LLOBREGAT SPAIN Doxinyl Doxycycline hyclate 100 mg/ml Oral solution chicken (broiler) 0,5-1,0 ml product/1 liter of drinking water/day 50-100 mg doxycyclini hyclate/1 liter of drinking water for 3-5 days Meat and offal: 7 days. Not for use in laying hens.

Poland Biofaktor Sp. z o.o.(Skierniewice) Czysta 4 96-100 Skierniewice POLAND Doxycyclinum 20 % Doxycycline hyclate 200 mg/ml powder for oral solution chicken, turkey 25-50 g product/1 liter of drinking water 10 mg doxycyclini hyclate/kg bw/day, for 3-5 days 1 Meat and offal: 4 days. Not for use in laying hens.

Poland Tarchomińskie Zakłady Farmaceutyczne Polfa S.A. Fleminga 2 03-176 Warszawa POLAND Doxycyclinum wet proszek Doxycycline hyclate 200 mg/g powder for oral solution chicken, turkey, 25-50 g powder/1 liter of drinking water 10 mg doxycyclini hyclate/kg bw/day, for 3-5 days Meat and offal: 7 days. Not for use in laying hens.

Poland Sogeval Laboratoires 200 route De Mayenne 53022 Laval Cedex FRANCE DOXYVAL 20 % Doxycycline hyclate 20 g/100 g Oral powder chicken (broiler) 5 g produkt/100 kg bw/day or 0,5 g/1 liter of drinking water 10 mg doxycyclini hyclate/kg bw/day, for 3-5 days Meat and offal: 4 days. Not for use in laying hens.

Poland Eurovet Animal Health B.V. Handelsveg 25 PO Box 179 5530 AD Bladel THE NETHERLANDS Soludox 15 % Doxycycline hyclate 150 mg/g Oral powder chicken, turkey, pigeon, cage bird 10-20 mg doxycyclini hyclas/kg bw/day 10-20 mg/ kg bw/day for 3-5 days. In case of Chlamydia psittaci infection for 30-45 days. Meat and offal: 7 days. Not for use in laying hens or in pigeons for human consumption.

Portugal CEVA Saúde Animal –Produtos farmacêuticos e Imunológicos Lda. Ceva Saúde Animal Lda. Rua Doutor António Loureiro Borges 9/9a 9o A Miraflores 1495-131 Algés PORTUGAL DOXYPRIM 400 mg / g Pó para Solução Oral para Suínos, Frangos e Perus. Doxycycline hyclate Doxycycline hyclate 400 mg / g Powder for oral solution Swine, Chicken, Turkey For oral administration in drinking water Broilers and Turkeys: 20 mg Doxycycline hyclate/kg bw, for 5 days. Chicken (Broilers) meat and offal: 5 days; Tukeys meat and offal:6 days; Not permitted for use in laying birds producing eggs for human consumption

Portugal DIVASA FARMAVIC DE PORTUGAL Produtos e Equipamentos Veterinários Lda. Parque Empresarial de Vialonga Armazém no 21 Casal do Bagulho Granja de Alpriate 2625-607 Vialonga PORTUGAL DOXYVET-10 Doxycycline hyclate Doxycycline hyclate 10g; Bromexin Cloridrate 1g Oral solution Bovine (Calves), Swine, Broilers, Turkeys, Ovine, Goat (Kid) For oral administration in drinking water Broilers and Turkeys: 50-100 mg/liter of water/day, for 3-5 days (Equivalent to 0,5-1 ml of DOXIVET-10 / liter of water/day Meat and offal: 5 days

Portugal DOPHARMA B.V. Zalmweg 24, P.O. BOX 205 4940 AE Raamsdonksveer THE NETHERLANDS VETADOXI 50 Doxycycline hyclate Doxycycline hyclate 500 mg/g Oral powder Bovine (Calves), Swine and Birds For oral administration in drinking water, milk or feed 25 mg/Kg bw in birds; 200 g/1 000 L water/day 3-5 days; 500 g/1 000 L drinking water birds Meat and offal: 5 days; Not permitted for use in laying birds producing eggs for human consumption

Portugal S.P. Veterinaria SA Crta. Reus Vinyols Km 4.1 Apartado 60 Riudoms 43330 (Tarragona) SPAIN Hidrodox 10 % Concentrado para solução oral para aves (frangos de carne) e suínos Doxycycline hyclate Doxycycline (as hyclate) 100 mg Concentrate for Oral Solution Chickens (broilers) and swine For oral administration in drinking water Broilers: 50 – 100 mg Doxycycline hyclate/L drinking water/day (0,5-1,0 ml of VMP/drinking water/day) 3-5 days. Birds (Broilers) meat and offal: 7 days. Not permitted for use in laying birds producing eggs for human consumption

Portugal Univete SA Rua D. Jerónimo Osório, 5 B 1400-119 Lisboa PORTUGAL UNIDOXINA 200 mg/ml solução oral para suínos e aves Doxycycline hyclate Doxycycline (as hyclate) 200 mg Oral solution Chickens (broilers) and swine For oral administration in drinking water Broilers and Turkeys: 20 mg Doxycycline hyclate/kg bw, for 5 days. Chicken (Broilers) meat and offal: 7 days. Not permitted for use in laying birds producing eggs for human consumption

Romania DELOS IMPEX' 96 SRL 17, Pictor Ştefan Luchian sector 2 Bucharest ROMANIA Doxidem 20 Doxycycline hyclate 200 mg/ml doxycycline hyclate Oral solution Poultry (not for use in animals from which eggs are produced for human consumption) Oral — 75 ml of product/100 litres drinking water/day for 3-5 consecutive days in young poultry up to 4 weeks — 150 ml of product/100 litres drinking water/day for 3-5 consecutive days in adult poultry Meat and offal: 28 days Indications: Poultry For the treatment of mycoplasmosis, pasteurellosis, colibacillosis, staphylococcosis. Chronic respiratory disease, infections caused by Pasteurella spp., Mycoplasma spp., Salmonella spp., E. coli., Haemophillus paragallinarium, Staphylococcus, hepatitis caused by Campylobacter and dermatitis.

Romania DELOS IMPEX' 96 SRL 17, Pictor Ştefan Luchian sector 2 Bucharest ROMANIA Doxidem 50 Doxycycline hyclate 500 mg/g doxycycline hyclate Water soluble powder Poultry (not for use in animals from which eggs are produced for human consumption) Pigs Oral (drinking water) — 20-40 mg of product/kg body weight/day for 5 consecutive days, per os; — 200-300 g of product/1 000 litres of drinking water for 5 consecutive days Meat and offal: 28 days Indications: Chronic respiratory disease, infections caused by Pasteurella spp., Mycoplasma spp., Salmonella spp., E. coli., Haemophillus paragallinarium, Staphylococcus, hepatitis caused by Campylobacter, dermatitis and other diseases caused by microorganisms sensitives to doxycycline.

Romania DOPHARMA B.V. Zalmweg 24, P.O. BOX 205 4940 AE Raamsdonksveer THE NETHERLANDS Doxycycline 50 % WSP Doxycycline hyclate 500 mg/g doxycycline hyclate Water soluble powder Poultry (not for use in animals from which eggs are produced for human consumption) Calves Pig Oral (drinking water) 40 mg/kg of body weight or 200-400 g/1 000 litres of drinking water for 4-7 days Meat and offal: Poultry 4 days Indications: — Ornithosis caused by Chlamydia psittaci in turkeys; — Colibacillosis caused by E. coli in chickens and turkeys; — CRD caused by Mycoplasma gallisepticum in chickens and turkeys;

Romania FRANVET ZI d'Etriche-Route d'Avire BP 103 49500 Segré Cedex FRANCE Doxy 5 Franvet Doxycycline hyclate 50 mg/g doxycycline (as hyclate) Water soluble powder Poultry (not for use in animals from which eggs are produced for human consumption) Calves Pig Oral (drinking water or liquid feed) — 1 g of product/1 litre drinking water/day for 3-5 days in poultry up to 2 weeks — 2 g of product/1 litre drinking water/day for 3-5 days in poultry over 2 weeks Meat and offal: Poultry 4 days Indications: For the prevention and treatment of respiratory infections caused by doxycycline sensitive microorganisms.

Romania INDUSTRIA ITAILIANA INTEGRATORI TREI SpA Via Affarosa n.4 42010 Rio Saliceto (Reggio Emilia) ITALY Doxipan 20 Doxycycline hyclate 200 mg/g doxycycline hyclate Water soluble powder Poultry pig Oral (drinking water) 5-7,5 g of product for every 10 litres of drinking water Meat and offal: Poultry 5 days Indications: Chronic respiratory disease and associated complications.

Romania PHYLAXIA PHARMA LTD 1103 Budapest Gergely u.79 HUNGARY Doxyphyl SP A.U.V. Doxycycline hyclate 300 mg/g doxycycline hyclate Water soluble powder Poultry (chicken, hens, turkeys) v Oral (drinking water) 10 mg/kg b.w. for 3-5 days or 100 mg of product/1 litre of drinking water Chickens, hens: 7 days Turkey: 7 days (not for use in animals from which eggs are produced for human consumption) Indications: For the prevention and treatment of several bacterial infections.

Romania LABORATORIOS SYVA S.A. Avda. Parroco Pablo Diez, 49-57 24010 Leon SPAIN Syvadox 10 % Doxycycline hyclate 100 mg/1 ml doxycycline (as hyclate) Oral solution Chickens (not for use in animals from which eggs are produced for human consumption) Oral (drinking water) 50-100 mg doxycycline/1 litre of drinking water/day (equivalent to 0,5-1,0 ml of product/1litre of drinking water/day for 3-5 days Chickens 7 days (not for use in animals from which eggs are produced for human consumption) Indications: Colibacillosis, CRD, mycoplasmosis – caused by previously mentioned germs sensitive to doxycycline.

Romania VMD Berendonk 74 2370 Arendonk BELGIUM Doxyveto 50S Doxycycline hyclate 500 mg/g doxycycline (as hyclate) Water soluble powder Poultry Swine calves lambs Oral (drinking water or feed) 20 mg doxycycline/kg b.w. /day in drinking water or 300 g of product/1 000 litres of drinking water or 600 g/1 000 kg of feed for 3-5 days Poultry 8 days Indications: CRD (Mycoplasma gallisepticum), Ornithosis (Chlamidia psittaci), Infectious synovitis (Mycoplasma synoviae), Fowl cholera (Pasteurella multocida).

Romania CHEMIFARMA S.p.A Via Don Eugenio Servadei 16 47100 Forli ITALY Doxiciclina 50 % Doxycycline hyclate 500 mg/g doxycycline Water soluble powder Broiler chickens swine Oral (per os, drinking water or liquid feed) 40 g of product/100 kg b.w. (20 mg of doxycycline/kg b.w) corresponding to about 15-30 g of product/100 litres of water for 3-5 days. Broiler chickens 5 days Indications: Chronic respiratory disease and other respiratory illnesses, specially produced by Pasteurella spp., Mycoplasma spp., Haemophilus gallinarium, Bordetella avium and Chlamidia psittaci.

Romania Lavet Pharmaceuticals Ltd., 1161 Budapest Ottó u. 14, HUNGARY Doxiprim 40 % Soluble Powder Doxycycline hyclate 400 mg/g doxycycline hyclate Water soluble powder Chickens turkeys (not for use in animals from which eggs are produced for human consumption) pigs Oral (drinking water) 20 mg doxycycline hyclate/kg b.w. Chickens and turkeys 4 days (not for use in animals from which eggs are produced for human consumption) Indications: treatment of respiratory, intestinal and systemic infections caused by doxycycline sensitive organisms: CRD (Mycoplasma gallisepticum, E. Coli), airsaculitis (Mycoplasma maleagridis), infectious synovitis (Mycoplasma synoviae), fowl cholera (Pasteurella multocida), infectious coryza (Haemophylus paragallinarum), colibacillosis (E. Coli), turkeys bordetellosis (Bordetella avium), necrotic enteritidis (Clostridium perfringens), chlamydiosis (Chlamidia psittaci). Prevention of secundary becterial infections due to stress conditions, vaccination, change of housing, transport.

Romania Novartis Animal Health d.o.o. Verovskava 57 1000 Ljubljana SLOVENIA Doxyril 50 % Doxycycline hyclate 500 mg/g doxycycline hyclate Water soluble powder Poultry (not for use in animals from which eggs are produced for human consumption) pigs Oral (drinking water) 25 mg doxycycline hyclate/kg b.w. during 3 to 5 consecutive days Poultry 4 days (not for use in animals from which eggs are produced for human consumption) Indication: Respiratory tract Infections caused by Mycoplasma spp. (M. gallisepticum, M. synoviae and M. melagridis), E. coli, Haemophylus paragallinarium and Ornithobacterium rhinotracheale. Enteritidis caused by Clostridium perfringens and Clostridium colinum. Septicemia caused by Pasteurella multocida.

Romania CEVA SANTE ANIMALE ROMANIA SRL 5 Chindiei, sector 4, Bucharest ROMANIA Doxyvit 50 % WSP Doxycycline hyclate 500 mg/g doxycycline hyclate Water soluble powder Poultry (chickens and turkeys) (not for use in animals from which eggs are produced for human consumption) pigs Oral (drinking water) 15 mg doxycycline/kg b.w. for 5 consecutive days or 2 g of product/10 litres drinking water and equivalent to 100 mg of doxycycline/litre of drinking water Poultry (chickens and turkeys) 7 days (not for use in animals from which eggs are produced for human consumption) Indications: Colibacillosis, CRD and mycoplasmosis, Clostridium perfringens, chlamydiosis, infectious coryza caused by Bordetella avium.

Romania Laboratorios Karizoo S.A Polígono Industrial La Borda Mas Pujades 11-12 08140 Caldes de Montbui Barcelona SPAIN Karidox 100 mg/ml oral solution for use in drinking water for chickens and pigs Doxycycline hyclate 100 mg/ml doxycycline (as hyclate) Oral solution Poultry (chickens) (not for use in animals from which eggs are produced for human consumption) pigs Oral (drinking water) 10-20 mg doxycycline/kg b.w. for 3 - 5 days. Poultry (chickens) t days (not for use in animals from which eggs are produced for human consumption) Indications: Prevention and treatment of CRD and mycoplasmosis caused by microorganisms sensitive to doxycycline.

Romania S.C. VIM SPECTRUM SRL 409 Sighisoarei Targu Mures ROMANIA Vidoxim 10 % powder for oral solution for pigs and poultry Doxycycline hyclate 100 mg/g doxycycline hyclate Water soluble powder Poultry (not for use in animals from which eggs are produced for human consumption) pigs Oral (drinking water) 1 000 g of product/1 000 litres drinking water for 5 days Poultry 10 days (not for use in animals from which eggs are produced for human consumption) Indications: Infections caused by Mycoplasma gallisepticum, E. coli, Bordetella avium, Haemophylus paragallinarium and Pasteurela multocida.

Romania S.C. VIM SPECTRUM SRL 409 Sighisoarei Targu Mures ROMANIA Vidoxim 100 % powder for oral solution for pigs and poultry Doxycycline hyclate 1 000 mg/g doxycycline hyclate Water soluble powder Poultry (not for use in animals from which eggs are produced for human consumption) pigs Oral (drinking water) 100 g of product/1 000 litres drinking water for 5 days Poultry 10 days (not for use in animals from which eggs are produced for human consumption) Indications: Infections caused by M. gallisepticum, E. coli, Bordetella avium, Haemophylus paragallinarium and P. multocida.

Romania CHEMO IBERICA, S.A. Gran Via Carlos III, 98 7a Edificio Trade 08028 Barcelona SPAIN Oridox (Soldoxin) 100 mg/ml oral solution for use in drinking water for chickens and pigs Doxycycline hyclate 100 mg/ml doxycycline (as hyclate) Oral solution Chickens (broilers) (not for use in animals from which eggs are produced for human consumption) pigs Oral (drinking water) 10-20 mg doxycycline/kg b.w. for 3 - 5 days. Poultry (chickens) 7 days (not for use in animals from which eggs are produced for human consumption) Prevention and treatment of CRD and mycoplasmosis caused by microorganisms sensitive to doxycycline.

Romania Huvepharma N.V. Uitbreidingstraat 80 2600 Antwerpen BELGIUM HydroDoxx 500 mg/g Water Soluble Powder Doxycycline hyclate 500 mg/g doxycycline hyclate Powder for oral solution Chickens (broilers) & Pigs (fattening pigs) Oral (drinking water) 20 mg doxycycline (hyclate)/kg x 3-5 days Meat and offal: Chickens: 6 days Do not use in laying birds producing eggs for human consumption Indications: Chickens (broilers): Prevention and treatment of Chronic Respiratory Disease (CRD) caused by Mycoplasma gallisepticum.

Romania CEVA PHYLAXIA VETERINARY BIOLOGICALS CO. LTD. 1107 Budapesta Szallas u.5 HUNGARY Doxivit 100 Doxycycline hydrocloride 100 mg/g doxycycline hydrochloride Water soluble powder Poultry (chickens, turkeys and goose) pigs Oral (drinking water) 10 mg doxycycline hydrochloride/kg b.w. daily for 5 days Poultry) 7 days (not for use in animals from which eggs are produced for human consumption) Indications: CRD (Mycoplasma gallisepticum, E. Coli), infectious coryza (Haemophylus paragallinarum), fowl cholera (Pasteurella multocida), colibacillosis (E. Coli), airsaculitis (Mycoplasma maleagridis), chlamydiosis (Chlamidia psittaci), necrotic enteritis (Clostridium perfringens).

Romania PHARMATEKA BT 1046 Budapest Szigyarto u. 10 / 20 Kossuth Str. Pusztaberki, 2658 HUNGARY DOXY H 10 % Doxycycline hydrocloride 100 mg/g doxycycline hydrochloride Water soluble powder Poultry Oral (drinking water) 1 g of product/1 litre of drinking water for 3-5 days Poultry 10 days (not for use in animals from which eggs are produced for human consumption)

Romania s.c. romvac company s.a.Şos. Centurii, nr. 7 Voluntari ROMANIA Doxiciclina 10 % Doxycycline hydrocloride 100 mg/g doxycycline hydrochloride Water soluble powder Poultry, including pigeons pigs bovine (calves) Oral (drinking water) 2 g of product/10 kg b.w./day for 5-8 days Poultry (chickens) 5 days (not for use in animals from which eggs are produced for human consumption)

Romania S.C. Crida pharm s.r.l 2 Intrarea Vagonetului Bl. 101, Ap. 47, sector 6 Bucharest ROMANIA Doxicol 60 % Doxycycline hydrocloride 600 mg/g doxycycline hydrochloride Water soluble powder Poultry pigs Oral (drinking water or feed) broiler 0-14 days: 50g/1 000 litres of water; broiler 15 -28 days: 100g/1 000 litres of water;broiler 29 -35 days: 120g/1 000 litres of water; Poultry 5 days (not for use in animals from which eggs are produced for human consumption) Indications: prevention and treatment of colibacillosis, respiratory diseases, mycoplasmosis.

Slovenia Novartis Veterina d.o.o. Verovškova 57 1000 Ljubljana SLOVENIA DOXYRIL 50 % Doxycycline hyclate 50 % (500 mg/g) powder for oral solution pigs, poultry Pigs and poultry: once a day, three to five days consecutively in drinking water Pigs: 20 mg of doxycycline hycate per 1 kg of BW; Poultry 25 mg of doxycycline hycate per 1 kg of BW Meat and offal: poultry: 4 days; Indications: respiratory infections (M gallisepticum, M, synoviae in M, melagridis), Escherichia coli, Haemophilus paragallinarum, Ornithobacterium rhinotracheale; Enteritis (Clostridium perfringens and Clostridium colinum; Septicemia (Pasteurella multocida)

Slovak republic Trei Bio pharmaceutical division, Industria Italiana Integratori Trei Via Affarosa n.4 42010 Rio Saliceto (Reggio Emilia) ITALY DOXIPAN 20 plv.sol. ad us.vet. Doxycycline hyclate 20 g/100 g Water soluble powder Calves, pigs, poultry-broilers, turkey for 5 days in drinking water Poultry-broilers: 5-7,5 g product/10 litre of drinking water Turkey:10-20 mg active substance/b. w. corresponding to 50-100 g product/100 liter d.w. Calves, pigs: 10 mg active substance/b.w./day corresponding to 0,5 g product/10 kg b.w. Meat: Broilers 5 days, turkeys 10 days, Indications: Broilers: chronic respiratory disease and assotiated complications Turkeys: infections caused by G-positive and G-negative germs, mycoplasmas sensitive to doxycycline especially respiratory and articular syndrom caused by mycoplasma and/or staphylococcus

Slovak republic DIVASA-FARMAVIC, S.A. CTRA. SANT HIPOLIT, KM. 71 08503 GURB – VIC SPAIN DOXIVET 10 % plv.sol. a.u.v. Doxycycline hyclate 100 mg/ml Water soluble powder Poultry: (chickens and turkeys), bovine and swine for 4 - 5 days in drinking water 0,5 ml of product/litre of drinking water Meat: 5 days Indications: Treatment of CRD, mycoplasmosis, porcine enzootic pneumonia, bronchopneumonias, chlamidiasis, unspecific diarheas.

Slovak republic Novartis Animal Health d.o.o. Verovskava 57 1000 Ljubljana SLOVENIA DOXYRIL 500 mg/g prášok na perorálny roztok ad us.vet. Doxycycline hyclate 500 mg/g Water soluble powder Pigs, broilers during 3 to 5 consecutive days in drinking water Pigs: 20 mg doxycycline hyclate/kg b.w. Broilers: 25 mg doxycycline hyclate/kg b.w. Eddible tissues: broilers 4 days. Indications: Treatment of infections caused by microorganisms susceptible to doxycycline, particularly: Broilers: respiratory tract infections caused by Mycoplasma spp. (M.gallisepticum, M.synoviae and M.meleagridis), Escherichia coli, Haemophilus paragallinarum and Ornithobacterium rhinotracheale, enteritis caused by Clostridium perfringens and Clostridium colinum, septicemia caused by Pasteurella multocida

Slovak republic Lavet Pharmaceuticals Ltd., 1161 Budapest Ottó u. 14, HUNGARY DOXYVIT 40 % plv.sol. Doxycycline hyclate 40 g/100 g Water soluble powder Poultry: (chickens and turkeys) and swine 3-5 days in drinking water, poutry in drinking water, pigs: in drinking water, in feed Chickens and turkeys:10-20 mg active doxycyclini hyclate/kg b.w.)/day, continual treatment: 1 g product/3-6 litre of drinking water, repeated treatment: 25-50 mg product/kg b.w.(10-20 mg doxycycline hyclate/kg b.w.) in drinking water Meat of chickens and turkey: 4 days, Indications: Treatment and prophylaxis of respiratory, intestinal and systematic infections caused by doxycycline sensitive organism: Chickens, turkeys: chronic respiratory disease (Mycoplasma gallisepticum, E.coli), airsacculitis (M.meleagridis), infectious synovitis (M.synoviae), fowl cholera (P. multocida), turkey bordetellosis (Bordetella avium), infectious coryza (Haemophilus paragallinarum), collibacilosis (E.coli), necrotic enteritis (Clostridium prefringens), chlamydiiosis (CH. psittaci),

Slovak republic Tekro, spol. s.r.o., Višňová 2/484, 140 00 Praha 4, CZECH REPUBLIC Meditek DOX 100 plv.sol. ad us.vet. Doxycycline hyclate 100 g/1 000 g Water soluble powder Broilers, pigs 3-5 days in drinking water Broilers: 10 mg doxycyclini hyclate/kg b.w (corresponding to 1 kg product/1 000 litre of drinking water) Meat of broilers and pigs: 7 days. Indications: Treatment and prevention of respiratory and gastrointestinal diseases caused by organism sensitive to doxycycline: broilers: CRD, mycoplasmosis, aerosaculitis, synovitis, pasteurellosis, infectious cholera, colibacillosis, chlamidiosis, necrotic enteritis

Slovak republic Pharmagal s.r.o., Murgašova 5, 949 01 Nitra, SLOVAK REPUBLIC DOXYGAL plv.sol. ad us.vet. Doxycycline hyclate 5 g/100 g Water soluble powder Pigs, poultry, calves, rabbits Poultry: prevention 5 days, treatment 3 days, in drinking water Pigs, calves, rabbits: 5 days, in drinking water, in feed Poultry: prevention: 50 mg active substance/1 litre of drinking water (1 g product/1 litre water), treatment: 100 mg active substance/1 litre water (2 g product/1 litre water) Meat of poultry and rabbits: 7 days Indications: Poultry: CRD (mycoplasmosis), colibacillosis.

Slovak republic COOPHAVET Saint Herblon 44150 Ancenis FRANCE RONAXAN 5 % plv.sol. ad us.vet. Doxycycline hyclate 5 g/100 g Water soluble powder Pigs, poultry, calves Prevention: 1-3 days, treatment: 3-5 days, in drinking, in feed 10 mg active substance/kg b.w./day (1 g product/5 kg b.w./day) Polutry: — less than 2 weeks old: 1 g product/litre of drinking water/day, — more than 2 weeks old: 2 g/litre water/day Meat of poultry 4 days Indications: Poultry: preventive and curative treatment of respiratory infections,

Slovak republic Laboratorios Karizoo S.A Polígono Industrial La Borda Mas Pujades 11-12 08140 Caldes de Montbui Barcelona SPAIN KARIDOX 100 mg/ml roztok pre podávanie hydine a ošípaným perorálne v pitnej vode Doxycycline hyclate 100 mg/ml Water soluble powder Chicken (broilers), pigs Broilers: 3-5 days, Pigs: 5 days, in drinking water Broilers: 10 -20 mg of doxycycline/kg b.w./day, (0,5-1,0 ml of product/litre of drinking water), Meat and offals: chicken (broilers) 7 days Indications: Chicken (broilers): prevention and treatment of chronic respiratory disease (CRD) and mycoplasmosis caused by microorganism sensitive to doxycycline.

Slovak republic CHEMO IBERICA, S.A. Gran Via Carlos III, 98 7a Edificio Trade 08028 Barcelona SPAIN ORIDOX 100 mg/ml roztok pre podávanie hydine a ošípaným perorálne v pitnej vode Doxycycline hyclate 100 mg/ml Water soluble powder Chicken (broilers), pigs Broilers: 3-5 days, Pigs. 5 days, in drinking water Broilers: 10 -20 mg of doxycycline/kg b.w./day, (0,5-1,0 ml of product/litre of drinking water), Meat and offals: chicken (broilers) 7 days, Indications: Chicken (broilers): prevention and treatment of chronic respiratory disease (CRD) and mycoplasmosis caused by microorganism sensitive to doxycycline.

United kingdom Laboratorios Karizoo S.A Polígono Industrial La Borda Mas Pujades 11-12 08140 Caldes de Montbui Barcelona SPAIN Karidox 100 mg/ml Oral Solution for use in drinking water for Chickens and Pigs Doxycycline hyclate 100 mg/ml doxycycline (as doxycycline hyclate) Oral solution Chickens (broilers) & Pigs Oral (drinking water) 10-20 mg doxycycline/kg x 3-5 days Meat & offal: Chickens (broilers): 7 days Indications: CHICKENS (BROILERS): Prevention and treatment of chronic respiratory disease (CRD) and mycoplasmosis caused by microorganisms sensitive to doxycycline.

United kingdom CHEMO IBERICA, S.A. Gran Via Carlos III, 98 7a Edificio Trade 08028 Barcelona SPAIN Soldoxin 100 mg/ml Oral Solution for use in drinking water for chickens and pigs Doxycycline hyclate 100 mg/ml doxycycline (as doxycycline hyclate) Oral solution Chickens (broilers) & Pigs Oral (drinking water) 10-20 mg doxycycline/kg x 3-5 days Meat & offal: Chickens (broilers): 7 days Indications: CHICKENS (BROILERS): Prevention and treatment of chronic respiratory disease (CRD) and mycoplasmosis caused by microorganisms sensitive to doxycycline.

United kingdom Huvepharma N.V. Uitbreidingstraat 80 2600 Antwerpen BELGIUM HydroDoxx 500 mg/g Water Soluble Powder Doxycycline hyclate 500 mg/g doxycycline hyclate Powder for oral solution Chickens (broilers) & Pigs (fattening pigs) Oral (drinking water) 20 mg doxycycline (hyclate)/kg x 3-5 days Meat and offal: Chickens: 6 days Indications: Chickens (broilers): Prevention and treatment of Chronic Respiratory Disease (CRD) caused by Mycoplasma gallisepticum.