He also has been appointed to the Committee on Molecular Pathogenesis and Molecular Medicine and to the Committee on Cell Physiology. His research focuses on the relationship between metabolism, diabetes and lipid (fat) storage. The overall focus of his lab is metabolic signaling. Dr. Brady is particularly interested in the insulin-mediated regulation of energy storage in adipocytes and hepatocytes, the interplay of glucose and lipid metabolism, the regulation of hepatic glucose production, and the molecular mechanisms underlying the development of insulin resistance in animal models and humans. His research is conducted using cell lines, primary murine hepatocytes and adipocytes, and samples collected from human fat biopsies.