She received her B.S. (Chemical Engineering, 1999) and Ph.D. (Chemistry, 2005) from the University of Illinois at Urbana-Champaign. She was a NIH postdoctoral fellow with Andy McCammon (UCSD). Rommie is the recipient of an NIH New Innovator Award, the Presidential Early Career Award for Scientists and Engineers, the ACS COMP OpenEye Outstanding Junior Faculty Award, and the ACS Kavli Foundation Emerging Leader in Chemistry National Lecturer (Spring 2016). She is the director of the NIH P41 National Biomedical Computation Resource and a co-Director of the NIH U01 Drug Design Data Resource. Her research is broadly concerned with the development and application of state-of-the-art computational methods to address outstanding questions in drug discovery and molecular biophysics.