A physician-scientist, he is the Director of The Children�s Hospital of Philadelphia�s Center for Applied Genomics (CAG), a high-throughput highly automated genotyping facility founded to identify the genetic causes of complex medical disorders in children, such as autism and cancer, with the objective of developing new therapies. The Center represents a $40 million commitment from CHOP to genotype approximately 100,000 children, a research undertaking that has gained nationwide attention, including news features in the Wall Street Journal, The New York Times, Time, Nature, and Science.