She obtained her Ph.D. from University of Pennsylvania, Philadelphia, USA, and carried out postdoctoral research at Yale University, Connecticut, USA. Her research interests fall under the categories of genomics, computational biology and systems biology. Her laboratory focuses on developing integrative computational models to understand the functional impact of genomic sequence variants. She is the leader of the genome annotations sub-group of the Pan-Cancer Analysis of Whole-Genomes project of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA).