After receiving his medical degree from Tishreen University in Lattakia, Syria, Dr. Makhoul obtained a degree in Endocrinology and Metabolic Diseases from René Descartes University in Paris, France. Dr. Makhoul was a resident in internal medicine at Penn State Geisinger Medical Center in Danville, Pennsylvania. Afterwards, he completed a fellowship in Hematology/Oncology at Penn State Hershey Medical Center in Hershey, Pennsylvania. Dr. Makhoul is certified in internal medicine, medical oncology and hematology. He is a member of the American Society of Clinical Oncology, American Society of Hematology and the American Association for Cancer Research. His research interests include resistant breast cancer to hormonal therapy and chemotherapy, GI malignancies and quality of life in cancer patients.