He investigates digital cultural heritage, human-centered design, digital archaeology, heritage data science, virtual museums, virtual reality and augmented reality, virtual worlds and serious games, and 3D visualization of the past. He received his Ph.D. in History and Computing from the University of Bologna, Italy with a dissertation on the visualization of medieval urban spaces. Lercari has worked on several digital humanities initiatives both in Italy (CINECA supercomputing center and University of Bologna) and in the United States (UC Merced and Duke University).