Her research investigates associations between weather, water, and Indigenous health in the context of climate change, and she collaborates with Indigenous partners to prioritize climate-related health actions, planning, interventions, and research. She is currently a collaborator in an international research initiative called the “Indigenous Health Adaptation to Climate Change” (IHACC) project, which works closely with Indigenous peoples and their organizations in the Canadian Arctic, Ugandan Impenetrable Forest, and the Peruvian Amazon, and she is also a co-investigator on the “Indigenous Peoples Adapting to the Health Effects of Climate Change” (IK-ADAPT) project. Sherilee currently sits on the Editorial Board of Epidemiology and Infection.