His clinic focuses on the treatment of gastrointestinal malignancies, with a particular emphasis on esophageal, gastric, pancreatic, and colorectal cancers. His research focuses on the design and execution of first-in-human and investigator-initiated clinical trials with correlative studies. He has a particular interest in non-invasive testing to identify and treat genomic drivers of treatment resistance. He has recently served on the ASCO Guidelines Committee for Locally Advanced Pancreatic Cancer, and he is a member of the GI Steering Committee for the Academic and Community Cancer Research United (ACCRU) clinical trial consortium.