He is a molecular biologist with an active basic science research laboratory probing the pathogenesis of glaucoma. He has two grant awards from the National Institutes of Health to study molecular and cellular aspects of normal and glaucoma eyes. His work involves culture of human eyes, histologic study of glaucomatous eyes, biologic studies of the trabecular meshwork and aqueous humor, molecular analysis of the glaucoma-associated protein myocilin, and epidemiology and clinical outcomes of glaucoma treatment. He is an expert in the culture of cells from the drainage tissues of the eye, and uses them to probe the genetic secrets of glaucoma.