His forte is treating sports or fitness related injuries. He is affiliated to Lilavati Hospital and has performed over 10000 knee operations. He believes in Holistic health and has authored books like Knee Problem No Problem, Real Fitness and Calm Sutra, the Art of Relaxation published by Times of India. He has scripted and anchored DVDs like Calm Sutra and Knee Problem No Problem, which emphasize on simple exercises to keep healthy and be happy. Dr Nadkarni is working towards popularizing the concept 'Vertical Yoga', which is a set of exercises that can be performed anywhere, anytime for mind and body bliss.