He obtained his medical degree from the University of Pennsylvania School of Medicine and completed a residency at the Hospital of the University of Pennsylvania. After completing a two-year fellowship at MD Anderson Cancer Center (MDACC), he joined the faculty of the Department of Head and Neck Surgery, where he is an active member of the Skull Base Tumor Program. A respected expert in robotic surgery and in the management of thyroid cancer, Dr. Kupferman is also medical director of the Voice Center at MD Anderson. He also represents the MDACC across all national and international locations, making him responsible for evaluating surgical standards and practices and providing expertise in oncology across all disciplines.