Starting his first career as a clinical pharmacist at Oita Medical University Hospital, he worked as a reviewer for drug approval at Ministry of Health, Labor and Welfare, and Pharmaceuticals and Medical Devices Agency (Japanese FDA), and then transferred to Hiroshima University. His research focuses on clinical pharmacokinetics and pharmacodynamics at target sites, especially for antimicrobial agents, with modeling and simulation techniques. He studied at Dr. Derendorf’s laboratory (Jul-Sep 2010) more about site-specific PK-PD and their pharmacometric application. He is a Fellow of American College of Clinical Pharmacology with more than 100 articles, and his work is awarded by several societies including International Pharmaceutical Federation.