Her research interests cover theoretical and practical aspects of constraint reasoning and optimization. Application areas include planning and scheduling, computational sustainability, embedded system design, energy systems, and smart cities. Milano is author of more than 130 papers and is editor in chief of the Constraints Journal and area editor for INFORMS Journal on Computing and Constraint Programming Letters. She was program chair of CPAIOR 2005, CPAIOR 2010, and CP2012. Milano is the coordinator of the EU-funded ePolicy project and is participating to two other EU project on smart cities.