He spends most of his time teaching anatomy to medical and graduate students in Cleveland and conducting museum collections research and paleontological research throughout the world, mainly in South America. Fieldwork has taken Darin to Australia, Madagascar, South America and the western United States. His research focuses on the evolution of mammals, especially those in South America. He also is interested in paleoecology (how extinct animals lived and interacted with each other) and the evolution of animals on island continents. Darin has taken part in many educational and outreach activities designed to teach people of all ages about paleontology, fossil hunting and mammals.