He graduated from Johns Hopkins University School of Medicine. For his professional training, Dr. Esnaola completed residency programs at Brigham and Women's Hospital and a hospital affiliated with Harvard Medical School. Clinical interests for Dr. Esnaola include stomach cancer, neuroendocrine tumors, and sarcoma (bone and soft tissue cancer). Dr. Esnaola's average rating from his patients is 4.5 stars out of 5. He takes several insurance carriers, including United Healthcare Platinum, United Healthcare Navigate, and Coventry. He has received professional recognition including the following: Philadelphia Magazine Top Doctors; America's Top Doctors, 2016, 2017; and Best Doctors in America, 2007-14. He speaks Spanish. He is affiliated with Fox Chase Cancer Center, Temple University Hospital (TUH), and Jeanes Hospital.