He received his B.A.S. in Computer Science from the University of Pennsylvania and his Ph.D. in Computer Science from Princeton University. Prior to joining Yale, Dr. Kleinstein worked as a Computational Scientist at Physiome Sciences, Inc. (Princeton, NJ), and as a research scientist at Princeton University, where he ran the Program in Integrative Information, Computer and Application Sciences (PICASso). His research combines techniques from dynamic modeling, systems biology, and bioinformatics to capitalize on recent advances in immune profiling methods to characterize diverse states of the human immune system (in health and disease, and following infection and vaccination).