He is the head of reconstructive urologic surgery and the Pediatric Urology Tissue Engineering Laboratory. In the laboratory, he is currently collaborating with Samuel Stupp, PhD., a leader in the field of nanotechnology, Daniel Harrington, PhD., and Arun Sharma, PhD. Together, they are investigating different methods of promoting tissue specific regeneration in the urinary tract with an emphasis on bladder regeneration. Current work involves the use of nanodesigned polymer scaffolds with different cell sources. Dr. Cheng currently serves as a member of the Society of Pediatric Urology Executive Committee, the Exam Committee of the American Board of Urology, the Editorial Committee of the Journal of Urology, and is Chair of the Professional Advisory Council of the Spina Bifida Association of America.