Bloodworth began her career as a watercolorist in Mississippi where she created realistic works concerned with texture and color that documented a landscape and time in the American South. After receiving an MFA in painting from Florida State University, Bloodworth moved to New York City to pursue her career as a painter. She turned to figurative painting with an emphasis on the portrait; attempting to both capture the personality of the subject and, in turn, reveal her own. In 2003, portraits of people that dominated her work became portraits of meals – intimate, personal representations of particular shared events.