She began composing on electric organ in 1990. Her first solo album, Ongakushitsu, was released from Nobukazu Takemura’s Childisc label in 1998 and reissued later on Jim O’Rourke’s Moikai in 2000. Since then, Tsuyuko has performed with Tortoise, Jim O’Rourke, Brokeback, Tara Jane O’Neil, Fountainsun and Yo La Tengo. She released HOKANE in 2006 and the live album Night, Dune, and Organ in 2015. Her newest album, Empty Talk, was released on the Japanese label ENBAN.