Recently, the Computational Biology Group was awarded funding to lead integrative analysis efforts of the modENCODE project and the NIH Roadmap Epigenomics Project . Dr. Kellis presented on his experience interpreting results from sequencing data by using functional annotation obtained from data sources such as ENCODE and the Roadmap Epigenomics Project. He also discussed how these methods relate to interpretation of variants from non-coding regions during whole genome sequencing.