Shes an artist. Shes on the faculty at Yale. Shes also part of an architecture and design firm known as MOS that was founded sometime in 2003 (according to its website) and that uses playful experimentation, serious research, and old-fashioned problem-solving in its work. The firm approaches architecture as a set of interrelated issues including traditional concerns such as building performance, fabrication, and structure as well as cultural, social and environmental networks. Some of MOS recent work includes a villa in Ordos, Inner Mongolia, as well as a public art installation called Afterparty at the P.S.1 Contemporary Art Center in Long Island City, N.Y. Sample is working on a book called Sick City: A Global Investigation into Urbanism, Infrastructure, and Disease. Her appearance at CCA is co-sponsored by the San Francisco Museum of Modern Art.