After growing up in Lapeer, Michigan, he attended Kalamazoo College for his undergraduate studies, followed by Chicago Medical School to obtain his medical degree. During his residency at the University of Michigan Hospital, he was drawn to the complexity of trauma, which led him to pursue a trauma fellowship at Vanderbilt University Medical Center in Nashville, Tennessee. Dr. Perdue then joined the Orthopaedic Department at Vanderbilt as an Assistant Professor for three years until returning to the University of Michigan Hospital in July 2013.