She has a longstanding interest in population genetics and gene regulatory processes, and how these shape phenotypic variability. Her lab collects and analyzes multidimensional human genomics data, particularly transcriptome data and genetic variation data, in the context of health and disease. Current projects include integrating regulatory genomics (including transcriptomics and proteomics) with human disease mapping, as well as characterizing the context specificity of genetic and epigenetic effects on gene regulation (e.g., cell and tissue type, sex, age).