She specializes in the diagnosis and medical treatment of patients with pediatric cancers, and researches the development of and screening for second cancers in childhood cancer survivors. Although treatment of childhood malignancies has become increasingly successful with a current overall cure rate approaching 80 percent, there are sometimes long-term toxic late effects of chemotherapy and radiation during critical periods of development, including second cancers and damage to vital organ systems. Dr. Henderson is interested in characterizing these second cancers and those who may be susceptible so that early and appropriate screening regimens can be developed.