He completed his undergraduate medical training in the Chinese University of Hong Kong. He received his doctorate degree at the University of Oxford, and has work on human genetic susceptibility to common infectious diseases. After joining the CUHK, he has been working on the gut microbiota in various digestive diseases. He is primarily interested in understanding the host-microbe relationships, and to develop biomarkers for various digestive diseases including colorectal neoplasia, inflammatory bowel disease and gastrointestinal infections.