He is an expert on the receptor-mediated adhesion of circulating cells, and has developed new computational and in vitro models to study the function of leukocytes, platelets, stem and circulating tumor cells under flow. His laboratory is testing in vivo several therapeutic strategies for disrupting cancer metastasis through the bloodstream. He has written textbooks on the subjects of statistical methods and microchannel flows, and received numerous awards such as the NSF CAREER Award, Outstanding Research awards from the American Society of Mechanical Engineers and the American Society of Clinical Chemistry, and is a James D. Watson Investigator of New York State.