He completed his Ph.D. degree in biostatistics from the University of Maryland, College Park, College Park, Md, USA, in 2001. He has served as Director of the Biostatistics and Data Management Core of the Florida Alzheimer's Disease Research Center (ADRC) for 5 years. His research areas include optimal designs of longitudinal studies, biomarker evaluation in longitudinal studies, case-control family data analyses, and early detection of Alzheimer's disease.