He received his M.D./Ph.D. at SUNY Stony Brook and trained in Internal Medicine at Washington University and in Medical Hematology/Oncology at Memorial Sloan-Kettering Cancer Center. He has a longstanding interest in antitumor antibodies, having defined the required role of Fc receptor engagement in the laboratory of Jefffey Ravetch at the Rockefeller University. His work at Columbia University continues to investigate the protective immunological mechanisms of antitumor antibody therapeutics.