As a neuro-oncologist, she cares for patients with brain tumors and neurologic complications of cancer including metastasis. As a scientist, she runs a laboratory-based research program focused on metastasis to the central nervous system (CNS), both leptomeningeal and parenchymal metastases. The laboratory employs multiple complementary approaches to identify and target cancer cell adaptations to the challenging microenvironmental constraints posed by the CNS.