His research work focuses on the development of next-generation High Performance Computing numerical simulation software libraries through the utilization of domain–specific high-level abstraction (HLA) frameworks. The key motivation of this research is to develop techniques to automatically parallelize an application while at the same time maintain near-optimal performance on diverse multi-core and many-core parallel systems. As part of this work Dr. Mudalige acts as one of the main developers of the OP2 and OPS embedded domain specific languages (EDSLs), two of the earliest high-level frameworks to demonstrate the significant utility of this novel technique for developing production-grade HPC applications. His current and recent research work includes projects with Rolls-Royce Plc, UK MOD, Imperial College London, University of Bristol, University of Southampton and STFC.