She established and directs the Vascular Health Unit at the McGill University Health Centre, where she conducts research projects on vascular structure and function, including the identification of novel pathways of atherosclerotic plaque instability, image analysis of atherosclerosis plaque composition, and arteriosclerosis, with special interest in arterial stiffness and hemodynamics in subjects with cardiovascular risk factors, such as hypertension, smoking, diabetes, dyslipidemia, and pre-eclampsia. Dr. Daskalopoulou's research has led to over 100 peer-reviewed publications.