Louis, MO. Jeff has been working in the preclinical field of endogenous “conditioning” of the central nervous system—in both the retina and brain—for more than 20 years, studying how to induce adaptive changes in gene expression to protect against injury caused by acute insults such as ischemia. His more recent interests involve strategies for modulating the duration of the conditioning response and thereby enhancing the translational potential of this approach for treating chronic neurodegenerative diseases, such as glaucoma.