Her primary research interests are in statistical methodology for mental health research, particularly related to causal inference and missing data. Her current methodological projects focus on best practices for the use of propensity score methods, methods for generalizing treatment effects from randomized trials to target populations, and propensity score methods that can account for measurement error in covariates. Her broad application areas of interest are mental health and education, with a focus on autism, evaluations of mental health policies (such as parity legislation), and suicide. She currently serves as Chair of the Patient Centered Outcomes Research Institute's Clinical Trials Advisory Panel.