He was the project leader of an NIH-sponsored study of the molecular basis of accelerated emphysema development in HIV-1 positive smokers, which was part of a Specialized Center of Clinically Oriented Research for chronic obstructive pulmonary disease (COPD). Dr Kaner is now Principal Investigator for a pilot study of doxycycline for COPD and emphysema in HIV-1+ individuals, and Principal Investigator of the Weill-Cornell site of the National Institute of Health (NIH)-sponsored Idiopathic Pulmonary Fibrosis Clinical Research Network. Learning Objectives: Top of page