Dr. Cooper has studied the genetics and biological mechanisms of drug action and resistance evolution in malaria since 1997. He has been part of the NIH team to discover the genetic basis of chloroquine resistance in Plasmodium falciparum malaria Since 2010 Dr. Cooper has been engaged in translational research on malaria in Uganda, where he studies drug resistant malaria in children, as part of a chemoprevention trial administered by UCSF. His work is now focused on artemisinin resistance evolution in Africa.