She has directed the development of various approaches to estimate exposure of large populations to heat, ozone, ambient fine particles, and environmental noise using statistical and mathematical models, GIS and satellite imagery. She has also directed a number of epidemiological studies to assess associations between exposure to air pollutants and asthma onset and exacerbation, as well as the prevalence and the gravity of systemic autoimmune rheumatic diseases. Much of her work is done in close collaboration with Public Health institutions to influence political decisions and orient public health surveillance and interventions.