Anne-Sophie has a track record in research on Quality of Life in patients with chronic conditions, including children and adolescents. She has been the principle investigator on a number of studies focusing on determinants of quality of life, such as coping, and interventions for patients and families to improve quality of life. More recently her research has focused on quality of life in Teenagers and Young Adults with cancer, as well as Paediatric Palliative Care. She has published widely on these topics and has strong links with clinical colleagues, as well as strong national and international networks.