Murillo identifies with the tradition of Abstract Expressionism, though he also cites the influences of Andy Warhol and Edward Hopper in his paintings. Though the imagery and motifs in his work have varied over time, Murillo has consistently worked with variations on a single technique. Working on a flat surface, he pours acrylic or polymer emulsion onto board, which he manipulates as though “they are liquid skins that can be pulled, pushed,” before covering the composition with a resin coating. Though earlier works were primarily abstract, Murillo has recently begun to experiment with sanding images on top of his resin works, the motifs in which often refer to commercial products and consumer culture.