From 1997-2005, he worked with the Evangelical Free Church of America International Mission (now called Reach Global) and taught at Nairobi Evangelical Graduate School of Theology (now called African International University, AIU). As associate professor of missiology and chair of the Missions Department, he led the development of a missions emphasis within the M.A., M.Div., and M.Th. degrees, as well as an M.A. program in Islamic Studies. Dr. Mekonenn has also taught at Denver Seminary for about eight years. For the last three decades, he has served the Lord as an evangelist, pastor, teacher and missionary.