He received a Ph.D. in molecular genetics and genomics from Wake Forest University. The goal of his research is to identify and functionally characterize genes contributing to cardiovascular disease risk in order to ultimately translate genetic discoveries into individualized patient care through pharmacogenomics and/or other clinical approaches. He is using his Translational Scholar Career Award in Pharmacogenomics and Personalized Medicine to investigate the genetic underpinnings and mechanisms underlying aspirin and clopidogrel resistance as well as determining optimal antiplatelet dosing. Lewis' honors include an NIH Extramural Clinical Research LRP Award, a Trainee Research Award from the American Society of Human Genetics, and a Training Fellowship in Cardiovascular Cell Biology from the National Heart, Lung, and Blood Institute.