Dr. Karakousis attended the University of Pennsylvania School of Medicine and then went on to complete his residency at Hospital of the University of Pennsylvania. Clinical interests for Dr. Karakousis include esophageal cancer, cancer surgery, and rectal cancer. He is an in-network provider for several insurance carriers, including Blue Cross/Blue Shield, Coventry, and TRICARE. He speaks Greek. He is professionally affiliated with Pennsylvania Hospital, Hospital of the University of Pennsylvania (HUP), and Penn Presbyterian Medical Center.