She is a Moore Investigator in Data-Driven Discovery. Prior to joining UT Southwestern, she completed a PhD in biophysics at UC Berkeley with Dr. Tracy Handel, where she studied the computational design of protein-protein interfaces. As a postdoctoral researcher, she developed a model for the evolution of new allosteric regulation and experimentally tested the idea of allosteric “hot spots” with Dr. Rama Ranganathan (at UT Southwestern). Her laboratory uses statistical analyses of co-evolution across genomes to map functional constraints within and between proteins. These statistical models are then tested for their ability to explain, predict and design cellular behaviors in the lab.