He leads projects in the use of information and communication technologies (ICT) in Evidence-Based Health care and is the co-founder and executive director of Epistemonikos, a non-for-profit organization created for promoting the use of the best available research evidence in health decision-making. He is currently working in technologies that combine machine and human collaborative efforts to generate knowledge, multilingual platforms for decision-makers, and automation of systematic reviews. He is co-director of the Southern American Branch of the Iberoamerican Cochrane Centre, conducts systematic reviews in different topics and provides methodological support to other reviewers in the region. He is also editor for the Cochrane Effective Practice and Organisation of Care Review Group.