Santangelo's current collaborative research endeavors include an examination of the validity and generalizability of writing assessment data, a series of comprehensive meta-analyses of the spelling and handwriting intervention literature, and an exploration of differentiated instruction in higher education. She is the author of numerous scholarly publications, former associate editor of Reading & Writing Quarterly, former editorial assistant for The Journal of Educational Psychology, and recipient of the American Educational Research Association’s Outstanding Student Research Award. With Carol Tomlinson, she recently authored a multimedia professional development resource kit titled Integrating Differentiated Instruction and Response to Intervention: From Theory to Practice. Her prior experience also includes nearly 10 years of teaching in diverse elementary and middle schools.