His research focuses on applying the principles of medical informatics to improve healthcare in low-resource settings, both within the United States as well as internationally. He has particular interest in user-interface design and user experience. His research builds on techniques developed through 10 years of experience building point-of-care electronic medical record systems in Malawi. These techniques are captured in the curriculum of the graduate-level Principles of Global Health Informatics course, and Global Health Informatics Summer Internship in Malawi, created and taught by Dr. Douglas.