He holds a PhD in Computer Science from Tufts University, where he was advised by Carla Brodley. Prior to joining UT, he was research faculty at Brown University, where he was part of the Center for Evidence-Based Medicine and also affiliated with the Brown Laboratory for Linguistic Information Processing. His primary research is in applications of machine learning and natural language processing to problems in health -- particularly in evidence-based medicine. Wallace's work is supported by grants from the NSF and the ARO. He was recognized as The Runner Up for the 2013 ACM Special Interest Group on Knowledge Discovery and Data Mining (SIG KDD) for his thesis work.