He is Co-director of the Pancreatic Cancer Precision Medicine Program, a Pancreatic Cancer Center of Excellence (PMCoE) program at Johns Hopkins and also leads a personalized immunotherapy/relational database program at the Bloomberg-Kimmel Institute for Cancer Immunotherapy. His clinical work is focused on multidisciplinary management for pancreatic cancer, bile duct cancer, liver metastases, and gastric cancer. He is the founding Editor-in-Chief of Annals of Pancreatic Cancer.