His research interests include export trafficking and signal regulation of G protein-coupled receptors (GPRCs). These receptors constitute the largest family of cell-surface proteins that modulate cell functions such as proliferation, survival, and motility. Recent studies have shown that GPCRs play an important role in the initiation and progression of multiple cancers. More interestingly, GPCRs may be used for the early diagnosis of cancers. Dr. Wu's studies may provide a foundation for the development of new drugs for prevention and treatment of cancers.