His career has included faculty appointments at the University of Pennsylvania, Vice-President of Clinical Pharmacology at GlaxoSmithKline, and Vice-President, Exploratory Development, at Incyte Corporation. Following his conversion to the Catholic Faith in 1997, he became President of the Philadelphia Guild in 2003. He also has served as coordinator of the Catholic Medical Association joint task force with the National Catholic Bioethics Center on Ethics in Medical Research.