Prior to his appointment at Vanderbilt, he was a Senior Associate Scientist at Bayer Corporation and an NIH/NRSA Fellow in the Department of Biomedical Engineering at Carnegie Mellon University. Professor Guelcher’s research focuses on the design of injectable grafts and drug delivery systems for regeneration of bone and cutaneous tissue defects, as well as biomimetic scaffolds for investigating the effects of the microenvironment on establishment of tumors in bone. He is an author of 56 publications and an inventor on twenty patents and published patent applications.