His research focuses upon the cellular and molecular mechanisms of motor neuron degeneration during ALS and he has recently discovered protein biomarker diagnostics for ALS and useful surrogate markers of ALS disease progression using mass spectrometry based proteomics. his work has been performed in collaboration with Dr. David Lacomis who provided samples and clinical information from ALS patient and control subjects. Dr. Bowser was the first to uncover a panel of protein biomarkers that can distinguish early state ALS patients (near time of symptom onset) from various control groups. He has lectured on this discovery at various international conferences and was honored as a Proteomic Pioneer by ProteoMonitor Newsweekly. He was also honored in 2005 byPittsburgh magazine as one of Pittsburgh’s 40 under 40 for influential young people shaping the region.