Dr. Chris Man’s laboratory is interested in applying computational and OMICS approaches to improve both the diagnosis and prognosis of pediatric cancer patients. The main focus of his research is to identify circulating and tumor biomarkers for early detection of chemoresistance and metastasis in pediatric osteosarcoma. Dr. Man and his lab are also interested in using bioinformatic and meta-analysis approaches to identify novel drug targets and pathways in pediatric cancers. The current projects include: 1) molecular classification of pediatric cancers based on genomic and proteomic profiling; 2) development of computational tools to integrate and analyze large-scale datasets; and 3) biomarker and target discovery in pediatric cancers using novel technologies.