Dr. Annesley completed her pediatric oncology fellowship at Johns Hopkins Hospital, where her research interests focused on the biology and targeting of molecular aberrations in high-risk pediatric acute leukemia. She joined the immunotherapy team upon coming to Seattle Children’s in September 2015. Dr. Annesley is part of the team involved with treating patients on the current PLAT (Pediatric and Young Adult Leukemia Adoptive Therapy) clinical trial with CD19 CAR T cells, and she is also involved in the development of future PLAT trials. She is particularly interested in identifying and treating the mechanisms of resistance and escape from CAR T cell therapy.