She received her B.S. from Sichuan University, Chengdu, China, and Ph.D. from Boston University School of Medicine. She studied hematopoietic stem and progenitor cell biology during her postdoctoral training in the laboratory of Dr. David Scadden. The Guo lab strives to understand the rules of cell fate determination. She is the recipient of Stem Cells Young Investigator Award in 2014, Gilead Sciences Research Scholar in Hematology/Oncology in 2015, and Charles H. Hood Foundation Child Health Research Award in 2016.