He was co-director of the Inflammatory Bowel Disease Center at the University of Pittsburgh and has served as basic science section editor for Inflammatory Bowel Diseases. His research interests include inflammatory bowel disease, innate immunity, cytokine biology and inflammation, and he has been the principle investigator for numerous clinical trials in ulcerative colitis and Crohn's disease. Dr. Plevy also works with Janssen Research & Development on immunology initiatives.