He is currently professor of Medicine at the Mount Sinai School of Medicine in NYC. He served as Director of the Kidney, Urology and Hematology Division, of the National Institute of Diabetes and Kidney and Digestive Diseases of the National Institutes of Health for 15 years. In collaboration with Dr. Vlassara, he focuses on preventing the absorption of food AGEs as a way of preventing aging complications as well as diabetes and its complications. He has authored hundreds of articles, books and book chapters.