He is a cognitive neuroscientist who uses multiple imaging methodologies to investigate the functional-neuroanatomical substrates underlying inhibitory and cognitive control and how this is organized in the prefrontal cortex (PFC). Dr. Depue uses both functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) to measure the brain’s response to certain behavioral challenges. In his previous research and training, he examined neural mechanisms involved in inhibitory influence in the interface between emotion and memory.