She uses environmental toxicogenomics, toxico-epigenomics, and systems biology approaches to understand the mechanisms of arsenic-induced carcinogenesis. A broad goal is to identify the genes and their encoded proteins that protect (or sensitize) humans to arsenic-induced disease. State-of-the-art technologies are used, including next generation sequencing to understand genome-wide consequences of arsenic exposure. Her lab studies arsenic-exposed populations with varied disease outcomes to identify signaling pathways that are differentially modulated in response to exposure. A major goal of the research is to identify mechanisms of prevention of arsenic-induced disease. Dr. Fry received her MS and PhD in biology from Tulane University.