Montclare is an Associate Professor in the Chemical and Biomolecular Engineering Department at NYU Tandon School of Engineering with appointments in Biochemistry at SUNY Downstate Medical Center, Chemistry at NYU and Biomaterials at NYU College of Dentistry. She is performing groundbreaking research in engineering proteins to mimic nature and, in some cases, work better than nature. She exploits nature’s biosynthetic machinery and evolutionary mechanisms to design new artificial proteins. Her lab focuses on two research areas: (1) developing protein biomaterials capable of self-assembling into supramolecular structures and (2) engineering functional proteins/enzymes for particular substrates with the aim of targeting human disorders, drug delivery and tissue regeneration.