His research involves applying molecular, biochemical, genetic, genomic, and computational approaches to the understanding of the mechanisms of environmental-agent-related organ injury and carcinogenesis. Recent work has focused on the molecular mechanisms of phthalate-induced carcinogenesis, mechanisms of ethanol-induced hepatic toxicity based on the latest knowledge of the genetic diversity of the mouse as a model organism, and genomic and genetic analysis of hepatic and renal toxicity of trichloroethylene to determine what genetic variants correlate with susceptibility or resistance to hepatic disease. Dr. Rusyn received his MD from the Ukrainian State Medical University in Kiev and his PhD in toxicology from the University of North Carolina at Chapel Hill.