Dr. Preston has been the principal or co-investigator of multiple funded grants focusing on community-based public health, cancer health disparities and health care reform. He currently works as a Health Services Researcher with the Robert Wood Johnson Foundation-funded National Coordinating Center for Public Health Services & Systems Research. His scientific interests are the development of strategies with a community-based participatory research approach that reduces cancer health disparities. His research agenda includes examining components of health care reform and how provisions of the Affordable Care Act address cancer health disparities among poor, minorities, and underserved communities.