His research is broadly driven by the interplay of security, networks and stochastic control with research contributions in the areas of Cyber-Physical Systems (CPS), Networks and Computing Systems, and Mobile Cloud Computing. His research work has been published in over forty refereed papers, posters and journals, and one book chapter. Guirguis' research and educational activities are funded with over $2.9M in grants from the NSF, DoD, AFOSR, DHS, IEEE, Cisco and Texas State. Guirguis received the NSF CAREER award in 2012.