He has been interested in the application of complex systems analysis to sepsis and inflammation since 1999, and worked primarily with using agent based modeling to create mechanistic models of various aspects of the acute inflammatory response. He is a founding member of the Society of Complexity in Acute Illness, and is also a faculty member of the Center for Inflammation and Regenerative Modeling at the McGowan Institute of Regenerative Medicine at the University of Pittsburgh. He has been a member of the Swarm community since 1999.