His work over the last 25 years has been supported by grants from the National Institutes of Health and multiple other public and private sponsors. Dr. Dagnelie has been the Center Principal Investigator for clinical trials of the Second Sight Argus™ 2 retinal implant (2007-present) and is now leading several follow-up studies of Argus II use in patients’ daily lives. In addition, he studies signals in the retina of retinal prosthesis patients, is involved in the development of psychophysical strategies for the Chicago intracortical prosthesis project, and is developing rehabilitation and assessment methods for visual prosthesis wearers and other individuals with ultra-low vision.