Silas’ research focuses on the design and implementation of hyperspectral imaging technology for preclinical and clinical diagnostics. He is currently developing a solid-state spectral illumination system for use in microscopy and in vivo imaging. In conjunction with in vivo imaging techniques, he has developed quantitative calibration phantoms and standardization techniques for small animal fluorescence imagers. He is also developing a system to perform time-resolved blood-oxygen saturation imaging. Silas holds an international patent for the development of multi-mode macroscopic-microscopic endoscope techniques for in vivo diagnosis.