She works on Artificial Intelligence, ethics and collaborative cognition. Her work is focussed on "Standardizing Ethical Design for Artificial Intelligence and Autonomous Systems". In 2010 Bryson published her most controversial work, "Robots Should Be Slaves", which selected as a chapter in Yorick Wilks' "Close Engagements with Artificial Companions: Key Social, Psychological, Ethical and Design Issues". She helped the EPSRC to define the Principles of Robotics in 2010. She has consulted The Red Cross on autonomous weapons and is a member of an All Party Parliamentary Group on Artificial Intelligence. In 2017 she won an Outstanding Achievement award from Cognition X. She regularly appears in national media, talking about human-robot relationships and the ethics of AI.