Pande's primary interest is in investigating static and dynamic compiler optimizations on evolving architectures. His research philosophy involves tackling practical problems which are relevant and important to the current issues in systems research and propose foundational solutions to them for good impact. Currently, his research is focused on developing compiler optimizations for embedded and configurable systems to improve code size, efficiency and power consumption. His work in this area has resulted in several techniques for efficient compilation given limited memory sizes, limited addressing modes and data paths on embedded processors. His research is primarily supported by the National Science Foundation and Defense Advanced Research Projects Agency.