His work with membrane-binding proteins has led him to focus recently on the mechanisms that govern the cell division cycle. Structural work in the Frost lab has led to direct, molecular scale views of the cell division machinery as it engages and reshapes cellular membranes. This approach has direct relevance to understanding many diseases, especially cancer. Several components of the cell division machinery have been implicated genetically in tumor formation, but until now there has been no direct method for studying their mechanisms of action. Education History