The proposed research project aims to test whether activating an energy signaling pathway can inhibit or delay liver cancer development in a mouse model. Funds are requested to purchase a homogenizer with a sawtooth generator that is required for this research. Dr. Stiles received her B.S. in Food Chemistry from Jinan University, her M.S. in Nutrition from the University of Tennessee-Knoxville and her Ph.D. in Nutritional Biochemistry from the University of Texas-Austin/MD Anderson Cancer Center. She completed two postdoctoral fellowships at the Howard Hughes Medical Research Institute and UCLA School of Medicine.