His research interests span the definition of computer architecture, including software design and optimization, to enhance the quality of mobile experience and improve the energy efficiency of high-performance computing systems. Reddi is a recipient of the National Academy of Engineering Gilbreth Lectureship honor (2016), IEEE Computer Society TCCA Young Computer Architect Award (2016), Intel Early Career Award (2013), and multiple Google Faculty Research Awards (2012, 2013, 2015). He is also the recipient of the Best Paper at the 2005 International Symposium on Microarchitecture, Best Paper at the 2009 International Symposium on High-Performance Computer Architecture, and IEEE's Top Picks in Computer Architecture awards (2006, 2010, 2011).