Her teaching and research draw on interpretive perspectives in disability studies and cultural studies and focus on questions of human vitality and precarity. McGuire’s book, War on Autism: On the Cultural Logic of Normative Violence (2016, University of Michigan Press), was awarded the 2016 Tobin Siebers Prize for Disability Studies in the Humanities. Her current research project traces the emergence of broad spectrum approaches to health and illness and reads these against the backdrop of neoliberal social and economic policies.