Her research focuses on model-driven engineering, software processes, evolution, and quantitative measurement of software size and quality. She is one of the creators of the Lindholmen Dataset, a collection of over 20 000 open source projects that use UML models. From 2014 to summer 2015, Regina worked in a French and a European project as a postdoctoral researcher at the University of Pierre and Marie Curie in Paris, France. She received her doctoral degree from the University of Potsdam in 2014 for her research on the evolution of model-driven engineering in practice.