Placed on a regimen of experimental meds that offer a mere 8% chance of success, he's forced to confront the very real prospect of his own mortality, which not surprisingly triggers a drastic realignment of his priorities. Looking for a companion to assist him in his final days, he hires Ira Wright, an earnest young comedian in desperate need of a break, to work as his assistant. Ira naturally jumps at the chance to be mentored by one of his idols, but quickly finds himself in over his head as he accompanies George on his perilous, chaotic journey of self-discovery and redemption.