Craig Venter Institute (JCVI). Dr. Li is interested in developing novel bioinformatics algorithms, computational methods and integrated workflows in genomics, metagenomics, transcriptomics, systems biology, protein structure and function prediction, computer aided drug discovery and so on. He is especially interested in addressing the Big Data challenges in various genomics fields with novel computational algorithms and high performance computing technologies. Dr. Li has contributed several computational methods to the community, including CD-HIT, an ultrafast sequence clustering program that is widely used.