Her lab uses computational and experimental methods to study how cells respond to stress during proliferation and regeneration. One focus is cancer cell proliferation and clonal dynamics during drug treatment and the evolution of drug-resistance, studied using computational modeling and cell culture experiments. Another focus is muscle wound healing in response to pressure ulcers, studied using mouse models and computational analysis of confetti-colored lineage tracing. Tucker-Kellogg received her training as an undergraduate in math and computer science at Yale, earned her doctoral degree at MIT working under joint supervisors in Computer Science and Biology, and conducted postdoctoral work under a Lee Kuan Yew Fellowship at NUS and the Mechanobiology Institute in Singapore.