She leads a research group that is focused on understanding the cellular and molecular mechanisms underlying neurodegenerative diseases. The ultimate goal of her research is to reveal novel therapeutic targets so that more effective therapies can be developed. Dr. Nash’s research group employs a multi-disciplinary approach, combining molecular and cellular biology, electrophysiology, biochemistry, behavioural studies in rodents, and genetic manipulation to address specific questions related to neurodegenerative diseases. Recently, Dr. Nash has shown that mitochondrial dysfunction is central to neurodegeneration in Parkinson’s disease, and is currently testing potential neuroprotective agents to prevent this mitopathology.