S. Mariani has authored and co-authored about 170 scientific publications. His main research interests are: numerical simulations of ductile fracture in metals and quasi-brittle fracture in heterogeneous and functionally graded materials; extended finite element methods; calibration of constitutive models via extended and sigma-point Kalman filters; multi-scale solution methods for dynamic delamination in layered composites; reliability of MEMS subject to shocks and drops; structural health monitoring of composite structures through MEMS sensors.