Clinically his interests include Chronic lymphocytic leukaemias (CLL) and low-grade lymphomas. He is core member of the NCRI Haematological Oncology Group and affiliated to the NCRI Haem Onc Chronic Lymphocytic Leukemia subgroup. His research interests are to gain insight into the behaviour of mature B-cell neoplasms by analysis of the characteristics and functions of the tumour B-Cell Receptor (BCR) Immunoglobulin (Ig). His major research achievements have been in origin and clinical behaviour of Lymphoproliferative disorders, including Chronic Lymphocytic Leukaemia Hairy Cell leukaemia and other Splenic lymphomas, by immunogenetic and molecular analysis.