He investigates means of improving oxygen delivery both to acute wounds (e.g., maintaining normothermia and administering 100 percent oxygen intraoperatively) and to chronic wounds (e.g., sympathetic blockade, local warming and hyperbaric oxygen therapy). This involves studies in animal models, human volunteers, and patients, along with developing better oxygen measuring techniques. A list of his publications can be found here: http://profiles.ucsf.edu/mark.rollins