He is group leader (Yeast Signalling Networks) at Instituto de Investigação e Inovação em Saúde (i3S), University of Porto. His research focuses on the role of bioactive sphingolipids and nutrient signalling pathways in the regulation of cellular processes, namely mitochondrial function, redox homeostasis, proteostasis and apoptosis, and how deregulation of these signalling networks impacts on aging and cell death in the context of neurodegenerative diseases. Researcher ID: A-2647-2008. ORCID: 0000-0002-7868-4663.