His research focuses on advertising and consumer culture in eighteenth-century America. He is currently writing a book tentatively titled Advertising in Early America: Marketing Media and Messages in the Eighteenth Century. His chapter on advertising in America prior to the Civil War will be included in the forthcoming Oxford History of Popular Print Culture. Keyes also publishes the two digital humanities projects featured in this presentation, the Adverts 250 Project and the Slavery Adverts 250 Project. He was elected to membership of the American Antiquarian Society in 2015