The Indianapolis times., 1930-12-29
hint ARTIFICIAL
CELL MAY LINK
LIVING, LIFELESS
Dr.. CriIe'S Experiment May
Prove to Be Aid in
Cancer Study.
BY DAVID DIETZ
lCopyrIEht. 1880. hy United Pressl


CLEVELAND, Dec. 29.-Artificial
cells, brought into existence in the
laboratory Of DR.. George w. Grille
at Cleveland clinic, may form a
link between the hfeless and the
living. 1t was revealed today in an
exclusive interview with DR.. Grille.
The calls procreated by division
tist as do many living unicellular
nilnals, such as the amoeba, and
lave exhibited reactions TO oxygen
A.nd TO poisons similar to that Of
living cells.
Further research may reveal that
ey are primitive cells resembling
e nearly the cells Of cancer and
e throwing important light
the study Of that disease.
Experiment Is Repeated
These facts we're revealed today
zen DR.. Grille for the first time
bcussed the work which has been
ng on in his laboratory and made
own details of the experiment,
VS. Of which leaked out a few
eeks ago and was published
iroughout the country as "the ar
fetal creation of life"
For the present" said DR.. Grille,
et Is regard the cell as some
ere in the vague ground between
lifeless and the living"
~ ~
eated the experiment for the
ritter, enabling him to see under
.ne microscope the way in which
'he "autosynthetic cells as DR..
Grille calls them, are formed.
Reaction Takes Place
A glass slide with little depres-
ion ground into its center was
placed under the microscope. In the
depression was placed drop of So
ution containing various salts. To
his was added a lipoid, a fat, which
bad been extracted from brain
Issue of freshly slaughtered an
imal.
At once, a reaction between the
Two took place. resulting in the
formation of tiny f1bers.
The artificial or "autosynthetic"
cell is completed by adding protein
from brain tissue.
When this is added, structures
ike tiny cells of living creatures,
only simpler and more regular in
form, come into existence Dr. Grille
calls them "autosynthetic" because
they put themselves together auto
as the various ingredients
are mixed.
Experiments Not Finished
L do not want to say at this
ime what the autosynthetic cells
are" DR.. Grille said. Our expert
ments are not finished. If news
had not leaked out prematurely, I
would not have discussed this mat
ter for months yet"
The cancer cell is barbaric and
primitive. It's only function is
growth at the expense of the other
! els, eventually killing them off.
The autoSynthetic cell resembles
the cancer cell in many ways DR..
erie said. "It, too, is a primitive
cell whose only function is growth" ="
DR.. Grille expressed the belief that
perhaps the formation of the auto
synthetic cell could be explained
upon the assumption that living
tissue contained many complex
Electrical Fields Cited
These molecules continued to
exist in the proteins and lipoids eX-
tracted from animal brain tissue.
"A salt solution is an electrolyte,"
ne continued. Its molecules break
up into electrified particles known
as ions. Hence there are electrical
fields in the solution.
THE complex molecules of the
proteins and lipoids are able by the
electrical energy of the salt solu-
rion to rearrange themselves into
cell structures. But apparently
these are primitive simple struc-
.tures lacking the fine detail which
long heredity gives to normal liv-
|lng cells.