New Britain herald., 1930-03-01
M'G|LL PHYSICIAN
 ID USE EXTRACTS
Dr.. Colip Ready to Give New
 Compound to Doctors

Toronto, March 1 (By Canadian Press) crystalline ex- tract, the discovery of which was recently announced to the world by Dr. J. B. Collip of McGill university, Montreal will be made available to physicians immediately, under cer- tain specific conditions. for treat ment of women afflicted with cer- tain functional disorders.
 Dr. Collip made this announce ment in a speech last night before a gathering of medical men, bio- chemists, chemists and research workers.
 Dr. Collip stipulated that all cases to be treated shall be thoroughly examined to determine if they fall into the classification of disorders already shown to be amenable to the extract treatment He also in sists that if they do, the patients shall be treated in d hospital anI under the most careful observation.
 Owing to the natural limitations of the production of the extract and the fact that the application of the discovery is still in the early stages. Dr. Collip feels that the greatest care must be exercised in it's use and experimentation by himself as well as others.
 Shows Real Possibilities
 Setting forth the achievements and possibilities of his extract thus far indicated, Dr. Collip said it had proved cncouragingly valuable in adjusting certain feminine disorders. Success had been obtained, he said, in dominant majority of cases treated. with restorations of normal functioning, gains in weight an1 vanishing of nervous afflictions. Dr. Collip added that a few pre- llmlnary tests had been conducted in cases of disorderly menopause and toXaemias of pregnancy. Enough success had been attained in these fields, he said, to warrant further experimentation.
 Discussing his early experiments with rats and mice, Dr. Collip paid tribute to numerous workers who had preceded him in the same field with varying success. He acknowl- edged particularly the work of Dr. Wesinger of Edinburgh university, who isolated and unpurified product similar in origin to Collip's extract, and whose work suggested the di- rection of the McKll scientists re- searches.
 It took more than a week of routine test, Dr. Collip revealed. Before he convinced himself that hu really had anything worth while. He at first placed little value on what he had extracted, but repeated experiments showed him he had something," he said. The first indi- cation was that the extract induced an exceptionally healthy condition and early maturity.
 Basic Dosage Found He also reported that early tests | indicated the basic dosage was .OOl of milligram and that practically the same results were obtained no matter how much larger the admin istration was made.
 Dr. V. J. Harding, professor O. pathological chemistry at the uni versity, disclosed that the number of deaths occurring yearly at the l Toronto General hospital from the abnormalities of pregnancy had been reduced by more than 60 per cent during the past few years.
 "Ten years ago." said Dr. Hard ing. We had an average of three or more deaths yearly from this affliction. In the past five years it has been reduced to one yearly, and if we have any in the next five years it will be our own fault'