The Lakeland evening telegram. (Lakeland, Fla.) 1911-1922, 1920-07-14
HOE CHOLERA
BY DR.. A. 2. Cline, v. S.

VI - - - ~ ~ ~ NJ NJ NJ w ~
The virus has not yet been success
fully cultivated, but very recent dis
coveries indicate that in the near fu-
ture the cultivation of it may become
practicable in the production of virus
for the purpose Of Experimentation
OF swine for the production Of anti
cholera serum.
q Hog-cholera virus is ultramiscro-
Escopic and passes through porcelain
filters. The virus retains virulence
IN fluids at room temperature for
from two to three months, but is de-
stroyed by heating to seventy degrees
Centigrade for one hour. When dried
It becomes more resistant to the in
fluence of high temperature. At the
temperature of an ice box the virul-
ence of the virus is retained for many
months. 1t is very resistant to dilute
solutions Of phenol, corrosive subli-
mate, and chimosol. The length OF
time that virus may remain virulent
on infected premises has not yet been
determined, but 1t easily survives a
single winter.
In addition to the filterable virus.
certain bacteria, including one Spiril-
lum, may be factors in the causation
Of hog cholera.
The bacillus suipestifer is no doubt
u factor IN the production and from
the original investigations under the
direction Of Salmon and some recent
experiments 1t seems more probable
that an occasional outbreak Of dis
ease very similar symptomatically and
anatomically 20 cholera is caused by
the bacillus suipsstifer that have been
recently isolated produce/a septicemic
disease that terminates fatally in
from one to three days. 1t has been
suggested that the disease produced
by the bacillus suipestifer be desig-
mated para-chUlera.
The bacillus suipestifer is short,
rod-shaped bacteria. 1t forms no
spores, or at least none have been
Demonstrated. TAis oeea1iGn srovs
aerobically and anaerabically on
practically all artificial media. It
will Withstand ordinary dessiccation
for months or even longer, but sun
light destroys it when exposed for
only a few minutes This organism
produces an acute or chronic inflam-
nation, and necrosis Of the intestinal
mucous and the mesenteric lymph
glands.
II the animals are previously
starved and the acid reaction of the
castle Juice neutralized before feeding
the cultures Of bacillus suipestifer,
they will contract an acute disease,
with symptoms similar to those OF
septicemia, and usually die on the
third day. Intravenous injections Of
tie cultures produce septicemia, re-,
sulting in death in from one to three
days. The infection with suipestifer
Is not transmissible from swine to
swine, and swine that have recovered
from the effects Of infection with the
bacillus suipestifer are still suscept
lille to the filterable virus. :
Bacillus suisepticus is frequently
demonstrated in the carcasses Of
swine that have died of hog cholera.
This organism is the causative agent
of swine plague, and will receive
proper consideration in the discus
sion of that disease. Suffice to say
at tbs place, 1t is frequently an as
ISOLATED infection with the filterable
virus, the disease resulting being
mixed infection Of hog cholera and
swine plague.
SYMPTOMS: Symptoms Of hog
cholera are as variable as the LESSONS,
For convenience On describing the
symptoms will be considered in four
groups corresponding to the four
types mentioned in the consideration
CT LESSONS.
Septisemic Form. The most acute
or so-called peracute cases are fire.
quently found dead, having evidenced
no symptoms The ordinary acute
cases evidence the following symp-
tens, usually in the order mentioned
The affected animals are inclined u
Isolate themselves and stand with
back and head hanging, or they may
crawl under the bedding. The appe-
lite is at first impaired, later the ami
mails refuse all food. In the early
stages vomiting in the beginning, but
This is succeeded by diorrhea. the in
iestinal discharges being mixed with
blood There is usually purulent
ronjunctivitis; the discharges accum-
liate on the eye-lashes and frequently
cause adhesion of the eyelids. There
may be limited mucopurlent dis
charge from the nose. On the second