Norwich bulletin., 1916-04-25
With Another Orderly at Boston Cit, Hospital Risks Test in InoeuIatic= for Scarlet Fever.


 The following relative to Hugh ". Rice, well known in this city ana Pomfret, appeared in a Boston paps- and proved of special interest to Put nam people:
 Holding their lives more lightly than their devotion to that science which combats the maladies that af- hict humanity, two young men, in full possession of mental and physical wig or, voluntarily submitted yesterday at the City Hospital, to an inoculation which injected into their veins, a sub stance believed to consist of germs of ! one of the diseases most dreaded by mankind.
 Frank B. Mallory, the distinguished pathologist of the Harvard Medical school His subjects were Hayward | R. c. Mott and Hugh W. Rice, who, for several months, have been serving | as orderlies in the City Hospital in cident to their training as nurses. The injection consisted of what Dr. Nal lory believes to be the bacilli of scar let fever.
 To Identify Bacillus
 Cognizant of the seriousness of the experiment to which they were to be subjected, the two young men made their wills before submitting them selves to the ordeal. They had been warned that, inasmuch as the power of the substance to be injected into them was unknown, the quantity de- cided upon for the experiment might prove too great, in which event death might come to them within 24 hours.
 Should the experiment prove success full, Mott and Rice will have scarlet fever in its worst form, and afterward
 will be exposed 60 those complications
 which so often follow the dread dis
 ease.
 The purpose of the experiment is to
 afford to Dr. Mallory an opportunity to identify bacillus. recently discOv-
 cred by him, and which he believes tc
 be the germ of scarlet fever. Should Dr. Mallory's theory prove correct, a 1 serum for the treatment of the dis ease will be quickly produced, and scarlet fever will be robbed of its ter
 TOTS.
 Human Test Essential
 Dr. Mallory announced to the medi cal profession several weeks ago tha ? he had isolated the bacillus of scarle IeVer, and that, as a result, he haC prepared a serum that he though
 would be effective es an antidOte. Tn
 principal object sought in the coura
 of the proposed experiments. however
 was the comDlete identification of rh 3 bacillus which Dr. Mallory believes U
 be that of scarlet fever. This ha | been tested on various animals in
 cluding rabbits and monkeys but I kwas observed that these were not If s | Tested by scarlet fever in the nQrne = that human beings yielded to it. l Q was essential. therefore. that the ba = cllIus be tested on men C- women. = Were Warned of D1nger = Dr Mallory and other physician s explained the dangers to the youn n orderlies who volunteered and wer g determined to go through with it. = Then another difficulty was encoun Il tered. The rules of the hospital pro O hibit dangerous experiments on ar taches of the institution. Mott an Rice, in the course of their prepara
 tion for certifiCates ss trained nurse. Y had been regularly entered on tn Il rolls of the hospital for a period ( l. two years. Of this period each ha s served IS months. It was necessar 3 for the trustees of the hospital to re o lease them from their service in orde -- that they might be the subjects of tn l. proposed experiments.
 $ Kept in SecIusion. V The desired release was fnall il granted by the trustees. Mott an - Rice were then told that their offe. le were accepted, and that in order to !
 prepared for the experiment the " would be isolated for a week. g For the last week. therefore, in 5 little room in Ward K, the two youn L. men have been kept in seclusio in Their friends were not allowed to wis ,- them. During those days they hal 10 been ke~t on a diet which was d. ,t signed to fortify their systems ,e combat the ravages of the disea, 'd which they were to risk
 , The inoculation of Mott and RiC l. took place little before noon yestel ye day. The injection was made by D Mallory, assisted by Dr. Edgar }
 Medlar, who is associated with hi
 in his pathological work. The seru,
 was injected into the membranes
 the tonsils. From the moment of il
 oculation the two men have been UT m der constant observation, though it
 not thought probable that the present
 of the disease will be manifest in lei NV than 4S hours.
 s It was reported late last night tn 1e the young men appeared to have SUI le fered no Ill effects of the experime1 1- up to that time.