Atlanta Georgian. [volume] (Atlanta, Ga.) 1912-1939, 1914-01-25

freshly narrowed ground. In describing one
experiment to show the effects OF the irritant
substance, the expermentsts write:
Portions of tumor extract prepared as
usual and with the usual bacterial control. were
passed through Berkefield filter The tumor
came from one of the fowls of filtration exper
iment two Filtrates and b were injected
separately In amounts OF ten cubic cent?
metres into the leg muscles Of three normal
fowls. Filtrate C. with and without an ad-
mixture of Kieselguhr was injected into the
pectoral regions of the same fowls. Nineteen
days later one had developed a tumor nodule
of 13 centimetres in diameter at the spot
where centimetres of nltrate with Kiesel-
guhr had been injected The nodule rapidly
developed to a dffuse mass, which led to the
death of the fowl after six weeks In all.
at this time a nodue had inst appeared in
the other pectoral region, where 10 cubic cen
timetres of fltrate C, without admixture had
been put. At autopsy another small discreet
nodule was found in the left leg as the result
of 10 cubic centlmetres of Nitrate A. without
Kieselguhr. The other two fowls remained
healthy"
The observation about the Irritating effect
Of Kieselguhr has interesting bearing on
human cancer. II Is well known that cancer
commonly appears In parts of the body that
are subjected to much irritation or injury,
From this discovery It seems that the cancer
may not be due TO the irritation, as is COM
monty supposed, but that the irritation only
increases The virulence of the causative agent.
One experiment showing how the cancer re-
sisted desiccation and freezing is recorded as
follows:
Fowl $40. carrying a large growth engen-
dered by a fltrate citrate experiment p was
killed and the tumor, which consisted of car
taginous and precartilaginous sarcomatous
tissue was ground fine and placed in a cold
compartment at several degrees below freez-
ing point, where in the course of forty-eight
hours It gradually froze solid. While still
frozen 1t was put in a cold desiccator over sui
phuric acid and the air exhausted until the
nanomt er showed pressure of less than
one millimetre of mercury. The desccator was
then placed Immediately in an ice chest. At
the md OF three days the material was taken
out and ground
at hed the form OF light brittle cake OF
nearly he bulk of the fresh tissue, was cottony
In texture and ground with great difficulty.
Twenty-four hours aftef grinding two grammes
of the powder were taken up in 25 centimetres
OF sterile water, and of the thick fluid FIVE
cubic centmetres were injected into the left
breast Of each OF five normal fowls Within
month one developed growth measuring
four by nine centimetres tan inch to two and
half inches). The tumor consisted of a spin
de-celled sarcomatous tissue undergoing car.
tilaginCus differentiation in the way charac.
teristic OF Chicken Tumor VII"
In his article in the Popular Science Monthly
Professor Leo lDCh SHOWS that the results OBJ
tanned by Rous and Murphy furnish an answer
to one Of the greatest problems that have puz.
gled cancer investigators
Professor Loeb first explains the abnormal
cell-growth which is characteristic of cancer
All organisms, plants we'll as animals. are
composed OF small units--the socalled cells in
which a nucleus is surrounded by protoplasm
and certain special structures. Each part of the
animal body is formed by aggregations Of differ
ent kinds OF cells. The skin and the cavities
within the body well as the glands are com