The Sentinel=record., 1914-03-17

Deputy District Attorney Hammon be- lieves the graduated syringe used in injecting the fluid was defective and hence air reached the neosalvarsan serum solution.
 Clinical reports on the medical his tory of the seven victims were pro- cured by Detective Bright and in none | was a description or notation of the | fatal injection operation.
 Dr. Stanley P. Black, speciau au | topsy surgeon, reported to Coroner | Hartwell that the seven deaths were caused by "an irritant poison as the | result of ntraspinal injection of neo- salvarsan"
 Dr. A. T. Charlton, when questioned | by Deputy District Attorney Hammon, asserted that at least fifty deaths had resulted in Los Angeles through injections of salyarsan and aeosal. varsan.
 Rumors that neither salvarsan nor neo-salvarsan was used in preparing the serum were vigorously denied by Dr. Charlton.
 Memberfs of the federal board of health suggested to Dr. Wheitman, su- peritnendent of the county hospital, yesterday that some of the neo-salval- san received in the shipment be sent to Washington for examination.
 Dr. Charlton's admission that he had never before given the neo-sal- varsan serum injection intraspi1ally created much comment among local physicians yesterday Many com mended this method of application as the only way by which relief could be given to persons suffering from locomotor ataxia, and others condemn ed it.
 1t was admitted that this method of treatment was almost in an experi- mental stage, although many physi clans have registered good results through it.
 Here is Dr. Charlton's statement of how he prepared and administered the serum:
 q first drew off a small quantity of blood from each patient and then re- moved the clots, leaving a serum with which | mixed salt solution and the two tubes of neosalvarsan. then heated mildly and placed in heremti- cally sealed tubes and placed on ice for twenty-four hours After another twenty-four hours it was administered Lin q graduated syringe, some of the patients receiving a greater dosage  than others. Harry Lane, the surviv- ing patient, received the first and largest amount of tne injection. All injections were intraspinally."
 The fact that the first patient to re- ceive the treatment did not die sug- gested the theory of a defective syr inge
 In the directions issued by the man. ufacturers some time ago this warn ing is given:
 "The solutions of neosalvarsan must on no account be kept or ar lowed to stand, but must be injected immediately after preparation, as | they oxidize even more rapidly than the solutions of salvarsan. Warning is therefore given against the practice of preparing quantities of neo-salvar- san solution sufficient for the treat ment of several patients. The phy' sician should dissolve afresh each dose for each individual patient, which 1 in consequence of the ready solubility gives no particular trouble'
 This warning was not observed" | Tlrtt O Supply Company yesterday Why | was this new treatment given? The | manufacturers of neo-salvarsan do not l advise the intraspinal injections" In answer to these queries, how ever Dr. Charlton points to medical journals and experiments performed 1 by eminent physicians. He asserts that the intraspinal injection is the only method of injection which will affect or allay locomotor ataxia. Another question which a well known physician raised was this:
 Did the operator mix the blood serums of the respective patients and form joint solution"
 1 According to Deputy District Attor- ney Hammon this was done when the fluid was placed in the graduated syringe Last night Dr. Charlton de. cined to discuss this phase of the case.
 | His friends stated that the young 1 physician is heart broken over the 1 tragedy.
 l
 FARLEY TO VISIT ROME.