The sun. [volume] (New York [N.Y.]) 1833-1916, 1914-01-18

THE ST
normal; two eases. tubcrcie bacllli nov
absent: fourteen cases. sputum reduced
to about a quarter: sixteen cases. tubercls
bacilli much reduced seventeen cases,
physical signs much improved
DR.. Wilson adds that he has been
very much impressed by the marked inn
provement In physical signs In the cases
that show other signs Of Improvement
the moist rsfes become markedly less and
the dulness clears up to n great extent.
leaving only bronchial breathing TO be
detected over the affected area"
Marked Improvement shown.
A detailed list OF each case follows in
which DR.. Wilson lists the results after
treatment. which in most of the cases
lasted about four months. Under the
heading physical Signs Dr. Wilson
writes, to take the first half dozen de-
tailed cases IN his paper. greatly i'm.
proved" marked Improvement marked
Improvement" very marked Improvement
cough only troublesome IN the morn
ing" marked Improvement" marked
improvement-patient able to walk few
miles
Opposite this the same patient one
learns, before the serum was injected was
scarcely able TO walk" Marked i'm
provement," or words OF the kind, with
patient able to get up" or patient up
and out" follow steadily for sixteen cases.
The seventeenth, eighteenth and nineteenth
cases show "no change" In physical signs.
The next two cases, one IL man NJ ~ IN
the advanced third stage OF consumption
following four years Of the disease showed
Improvement The last four cases listed
are those of patients who died.
The preliminary communication paper,
Notes on the Treatment OF Sixty-nine
Cases Of tuberculosis" by Drs. Mcclure,
Bancroft and Thomas. lists the weight OF
each patient before contratoxin was In
tect,d, the number of injections ,thc low
eat five. the highest forty injections), the
weight of each patient at the tune the
paper was written aud the amount gained
or lost after Tn" treatment.
The table shows that thirty-seven
gained in weight. the Individual gains
ranging from one 10 as high as cighty-one
pounds Eight patients neither gained
nor lost weight after the treatment.
Twenty four lost weight, the losses run
ming from one pound 10 ten pounds,
what Experimenters Say.
some oC the other statements OF the cS-
pcrimcn;crs IN this paper are:
"Of the tifty-onc cases IN whom dag
'NSlf u'ItluS ltl plliN wv wv PllN El' ~
signs hut on the presence of tuberclo
hacilli IN the sputun. thirteen. who all
had tuberculosis sputum at the commence
meut OF treatment. have now no tubercle
baclli In the expectoration.
Twenty-three show very marked rrduc-
tion In the number of bacilli present. and
not only are the haclli very much re-
duccd but phHgocytosis ls very active in
the sputum and the bac,lli tend to he
granular M in .lpNx n 1sr.pgTn-
ton. In the remaining fourteen
cases who have had tubercle pacilli In the
sputum the condition Of the bHcilli as FAR
as has been observed. Is practically the
same ~ when first examined. but II
should be noted that twelve OF these are
recent cases and have only had "a small
number OF injections. In all the
cases with measurable quantity OF
sputum there has been notable decrease
IN the amount UP u date"
Where collateral catarrh was present
In the lungs IN siNty-two out Of SIXTY
seven cases the catarrh either "disap-
p"ar'd ur hcCam, distinctly less" follow
ing the treatment. the writers Say IN their
paper. aud also the physical signs of
tu5crculous origin have become less eNi.
dent"
Under the line General Conclusions"
Drs Mcclure. Bancroft and Thomas say
among other things.
'rh" Impression which treatment by
coutratoNin No I has given w. up to
the present is that the remedy Is applicable
to ali stages Of pulmonary tuberculosis
Is I'm NO way harmful To- any case and may
be tried with any patient whose condition
n such as reasonably 20 warrant any
interference, 1T al II j. convenient ~
administration. The injection is
given simultaneously between the shout.
ders and IN no instance have We noticed
any local or focal reaction
NO serum disease has been obs.rv ed.
nor any clinical evidence of hemolysis and
IL naturally follows that. although In GER
tain cases dosage WAS spaced To carry
the patient into the dangerous ZONE. no
symptom Of even mild anaphyiaNis has
been observed"
Or Bancroft In subsequent paper In
the collected Records goes further IN h!s
Endorsement lie concludes this second
pap"r with u paragraph that runs
"MN experience up 10 the present leads
me to consider cuntratuxin as the best
method Of treatment before tn. medical
public AZ the present tin' and one which
can readily be combined with san!tariuu
or other procedures Of general hyg"uic
management II ~ certainly very much
simpler to administer this serum and very
much less irksomc To the patient than a
course Of tuherculiu would be. The
average results practically are as good.
or better. than those obtained in tn" small
proportion Of cases that recover perfectly
under the tubcrculir treatment and It
Will probably be found that the duration
OF the treatment Is much shorter
OF this serum Dr. M-hnarto himself says
in his preliminary note In the collected
Records that the clinical results which
have followed the use OF coutratoSn in
the disease in which 1t has been most
completely tested namely pernicious