The Washington herald. [volume] (Washington, D.C.) 1906-1939, 1913-03-31

Very quick repetition of the injections.
the highest degree Of nonvirulence and
harmlessness Is reached by depriving
the bacilli In question of their original
natural condition, and forcing them for
a long time to adapt themselves quick
~ to artificial cultural materials and
conditions of flfe, and in this way even
the last trace of virulence is destroyed.
OF those bacilli completely deprived
OF their virulency in this way, after
ward great quantities are born with
out harm. and so smoothly accepted
by the organism as has not been pos
sible before in any other way.
Moreover, by this invention We OBJ
tain curative or protective serum in
such a way that of products gained In
the manner just described-that Is to
say, these now absolutely nonpoison-
GUS cultures, repeatedly exposed to
passages through the body Of man or
related TO animals, or by leaving them
for some time in those bodies. and by
breeding the bacilli changed in this
way in proper cultures-extraordina
fly large quantities, for example. one
or several drains, can be successfully
used in these passages through the
proper bodies. For II. after some
what lengthy stay. perhaps after eight
or twelve months. all the bacilli have
not yet succumbed either to complet"
gradual resorption or dissolution. we
gain from the surviving bacillt prod
ucts which still show considerable IN
crease Of immunity and curative value.
Flu. Their Description.
As first material for the procedure IN
question, the tubercular bacilli Of the
turtle can be used as described in the
.-CentraIblatt, Fuer Bacteriologie, Para
sites, and Infectional Diseases" 1903.
Chapter I. volume "a. pages SAT to 6Ss.
and pages 795-S9.
Curative and protective serums pro-
duced according to the different ways
nf the present procedure are used either
dry Or in suitable emulsions or suspend
ed in solutions.
The employment Of curative and pro-
tective serums gained according to this
invention in emulsions or solutions may
be made, for example, by the use Of
water, solution of salt. broth, oils. fats,
or any other appropriate means.
The ''Naehrboeden" contain curative
and protective matter. However, they
are free Of harmful secondary effects. as
no dangerous poisons are in them. Con-
seauently the solid or fluid "Naehrboe-
dem on which the culture have been
bred can be used with good success
both alone or with, proper additions, and
also together with the bacilli instead Of
the bacterial emuisions or solutions men
toned above.
Besides their employment for injections
these emuIsions, or solutions (suspension-
en), or the solid or fiued ''naehrboeden."
separated from the bacilli can be used for
external applications, as, for instance,
salves, plasters and so on for
local application on tuberculariy affected
parts Of the body.
II then, for curative effect, such cura-
tive material containing living bacilli Is
applied to the person 1t Is possible to re-
produce other cultures FROM the SUBJ
stances taken from the person treated.
For instance, from secretions or from
protective and curative preparations pro-
duced according to this present invention
1t is possible to produce available ma
terial. II such substances or preparations
still contain living bacilii Cultures pro-
duced in this way can be used either for
Immediate curative~purposes or for fur
Their production of other cultures.
The production Of curative and protec-
tive materials can be obtained. accord
ing ia this present invention. BY working