davidaulloa/AmericanStories huggingface dataset:
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
TOOK OUT THE PHONES.
Young Men Wanted to Use Them,
but Took Them Outdoors.

AOuhS wen wanted to Use Them,
bus Took Them Outdoors.
At 7:3O yesterday morning two en-
ployes of the Northwestern Telephone
company entered Voegeli Bros drug
store at the corner of Washington avenue
and Hennepin avenue. and asked if they
might use the Northwestern Telephone
company's phone. The young man in the
store assured them they were perfectly
welcome 10 use the phone if they
wished, and directed them to the in
strument. He then went back to wait
upon customers.
The telephone men cut the wires con-
meeting the instrument and without walt
ing to remove the screws which fastened
the telephone to the wall, jerked 1t loose
and left the store with it in their pos
session.
They called at the Thompson drug
store, at Third street and First avenue
south, and informed Mr.. Thompson that
unless he would sign a contract, in which
he would agree to refuse the use of the
telephone to all persons except those
who presented the Identification cards
provided by the company, they would
remove his telephone, and told him that
they would give him until this morning
to decide what he would do. 1t is under
stood that they viii be permitted to re-
move the instrument today.
At the drug store of A. B. Hermann,
Fourth street and Second avenue south,
Mr.. Hermann being absent on account of
sickness, the clerk was told that he mus:
demand to see the cards of all persons
wishing to use the Northwestern Tele-
phone IN that store. The telephone
would be removed unless the rules were
complied with.
Gamble & Ludwig's drug store, Henne-
pin avenue and Third street, was also
visited and Mr.. Gamble was given the
option of refusing the use of his tele-
phone to all persons not possessing cards
CT having 1t removed.
special meeting of the druggists as
sociation has been called for Monday
evening, when 1t will be decided what to
do.
G.. P. Wainpan, general manager of the
Northwestern Telephone company, stated
yesterday that he had the telephone in
VoegeIis store removed because Mir
Voegeli was not living up to the contract
He said that he had warned Mr.. Voegen
repeatedly not to allow the public to use
his telephone, but that 1t had apparently
had no effect, and the instrument was
consequently removed. He said that h"
believed he had a right to enforce TIE
contract rules.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
TWO MEN BURNED.
j. McAdam and w. ID. Kelly Lose
Their Lives.

Their Lives.
GRAND FORKS, N D., Feb. 1.-(Spe-
cial)-Two of the oldest citizens of Grand
Forks met death yesterday morning In
the fire that destroyed the Kelly & Gil.
lam saloon. w. D. Kelly, one of the pro-
prietors, and 7. ]. McAdam were mis- led
last night, and their charred bodies found
this morning The two men left Dan
Sullivans saloon about 4:20 yesterday
morning to go home, and were never
again seen alive. 1t is supposed that in
passing Kelly's place they had smeled es-
Gaping gas, and had gone into the base
ment by an outer stairway to investigate.
The theory is that on entering they hal
lit match, which caused the explo son
that occurred about o'clock, badly shak
ing the building, and setting it on fire.
The building and stock were an utter
ruin. Loss, about 81, 900; insured. The alb
sence Of the two men was not noticed I'M
til evening, and then sea! oh was begun
for them, resulting in the discovery of
the two charred bodies in the basement
about 2 o'clock this morning. The bodies
were locked in each others arms, indi-
eating that one had attempted to carry
the other out.
Kelly was thirty-eight years old, and
unmarried. HIS mother and sister live In
Grand Forks, and other friends at Hud-
son, Wis, where the body will be shi J.
ped tonight. McAdam was forty-eight
years old, and leaves a family. The
Knights Of Pythias took, charge of his
body.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
AMERI6A SAYS SO.
The Entire Country is on
the r.. ".
Cascarets Candy Cathartic Did 1t, and
Record Phenomenal Victory.
Five rliliion Boxes Sold Last Year.

From every part of America comes the
news that sufferers from constipation
have found relief in Cascarets Candy
Cathartic, the wonderful modern scien-
tihc laxative and intestinal tonic Cas-
carets are fguratively and literally in
everybody's mouth. Thousands have tried
Cascarets with the most pleasant and
effective results, and voluntarily testify
to their experiences Here are a few
extracts from some of the letters:
II have been using Cascarets for head
ache ache and csonstipation and have received
Ter. 5l2 Larrabee St. Chicago.
II have been taking Cascarets for over
a month and find them just the thing fof
ST.. Andover. Mass
II am using Cascarets and have never
found anything so satisfactory" Mrs. G.
W. Durrant. 81 Emerson St.. Buffalo,
Il have taken Cascarets and cheerfully
recommend them to all my friends Mrs
G. J. Gradwell. Frugality. Pa.
"Cascarets are fine for bilicusness and
Mrs Mary Cummings Maud, Oklahoma
II use Cascarets in my family and find
them all you recommend them to be-" E.
l.. Irwin, Cor. Mead and Railroad, Mead
you can safely add appendicitis to the
list Of diseases that Cascarets will beneht
or cure" Eunice ]. Smith, Rich Valley,
II have used Cascarets; there is moth
ing better for constipation" Benz. Pas
sage knightstown, Ind
"Cascarets are all right. They have
cured me of constipation, and I never
expected anything would" Charles H.
Nye, Lock Box 2Oo. Cincinnati. Ohio.
II am so thankful for your Cascarets.
They are better than any medicine I
ever used Mrs. M. Rev. Lacelle. Iowa.
i do not hesitate to say that Cascarets
is the very best medicine ever placed be-
fore the people" Andrew Woodruff,
10
"Cascarets are the best cathartic ever
used. Tom Holt, Wildwood Manitoba.
Il have tried your Cascarets and want
to tell you they are just splendid" John
Wiegmink, Bob $751; Allegan, Mich.
We could fill the whole paper with ex-
pressions like the above. Thousands Of
similar recognitions Of the merits of Cas-
carets have been volunteered and prove
that this delightful laxative, so pleasant
of taste, so mild and yet effective, has
hearts of the people.
Go buy and try Cascarets yourself to-
day. All druggists. 10c, 25c, SOC. Booklet
and sample free. Address Sterling Rem
edy Company, Chicago or New York.
This is the CASCARET tab
let. Every tablet of the only
I m r. m I genuine Cascarets bears the
| IL. V.ll. | magic letters "CCC." Look at
a the tablet before you buy,
C-D and beware of frauds. imita-
tons and substitutes.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
UNKNOWN MAN KILLED.
Run Down by Freight In the
Hastings Yards.

HASTINGS, Mimi, Feb. 1.-(Special}-
An unknown man was killed by west
bound freight No. 81, Conductor w. II.
Murphy in charge, this afternoon, in the
lower yards, the wheels passing over his
chest and left hand. Il is presum ed he
attempted to steal ride. He was fairly
well dressed, and aged about twsnty live
years, weighing, poss by 1855 u-ds. Tne
victim was of sandy complexion, with
brown hair and 4 small mustache, five
feet nine inches in height, and Wore a
fireman's coat. Coroner Nicholas Gillen
deemed an inquest unnecessary. The body
is yet unidentified, but it is thought the
man was given lodgings at the city hal
last evening, registering the name of
George Doss. An empty bockatb ok va,
the only article found upon his person.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
SECRETARY CAGES REPORT.

Discussion of 1t Used Up Time of the
Senate.
WASHINGTON, Feb. NEARLY the en-
tire morning hour in the senate today was
occupied by Mr.. Allen Pop, Neb.) in the
discussion of the report Of Secretary
Gage concerning his transactions with the
National City Bank of New York.
Mr.. Daniel (Dem., Va) made an ex-
tended speech on the pending financial
measure. He vigorously opposed the prop
osition that the country should go to
the gold standard.
Daniel M. Ramsdell, of Indiana, and
Charles G. Bennett, Of New York, were
sworn In as sergeant-at-arms and sec
rotary Of the senate, respectively.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
ACCUSED OF MURDER
THE DEATH OF JOHN
ROBSON
A SENSATION AT SIOUX CITY

The Prisoner Had just Arrived From
saltwater, Where He Has Been
Completing One of RObson's Con-
tracts-The Arrest Made on a COM
pInint sworn to by II Private De-
tective-Story of the Crime.
SIOUX CITY, Feb. IA profound SEN
sation was created in Sioux City this
morning from the fact that Oscar A,
Goodrich, a prominent contractor and
Mason, has been arrested on the charge
that he is the murderer of John Robson,
who met his death in a foul manner the
night of Dec. 30, in his Office in this city.
Goodrich arrived in Sioux City at 5
o'clock this morning from Saltwater,
Mimi, where he has been finishing one
of Robson's contracts. The sheriff went
to the sleeper and placed his man under
arrest. He was at once taken to the
county jail, where he was locked up
Goodrich, up to two years ago, was the
senior partner of the firm of Goodrich &
Robson, the Junior member of which IS
the murdered man. They have done rail-
way and bridge work in all parts of the
West, and the fact that Goodrich is ac-
cUsed now of the murder of his partner
has come like shock to the community.
Henry Morrison, a private detective,
swore to the information and declares he
has sufficient evidence to secure a con-
viction. Just what this is he refuses to
divulge. At any rate, several officers
suspected Goodrich, but a woman swore
she was with Goodrich the night of the
murder, or at the time it took place.
Goodrich declares his innocence.
1t was IL o'clock at night that Robson
entered his office, and had no more than
stepped inside when he was struck en-
the head with Ratchet. 1t went two
inches into his skull, and he lay all night
unconscious and in the cold in a pool of
blood. Next morning he was found, bur
could not tell who struck him. Two days
later he died. A reward of $1,000 is up
for the arrest and conviction Of the muir
derer.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
New Train Service.

KEYSTONE, S. D., Feb. lit has been
into this city from Hill City will make
connections with the accommodating
freight. which leaves Deadweod at 1
City at 10. The train will arrive in this
city shortly before II. 1t will leave in
the afternoon in time to connect with the
passenger going south, also the freight
going to Deadwood This will give COM
mercial and business men an opportunity
to make this city in one day, either from
the north or south
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
Prohibition Convention.

WADENA, MINI, Feb. 1-(Special.)-
The Prohibitionists of this colrntv. held
their first county conventlonsIIl this city,
and elected delegates to tbs state con-
discussed plans of WORK for the coming
campaign. A county committee was
elected, consisting of c. M. Smythe, of
Verndale, chairman; j. A Williams, of
Thomastown; Oscar Johnston,of Sebeka :;
j. M. Date, of Menahga J. M Stowe,
r. r. Atchinson and H W. Fuller, of
Wadena. A rally was held at the court
house in the evening, and w. G. Calder
wood, secretary of the state central com
mittee, and ]. w. Leedy, of Minneapolis,
delivered addresses.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
Contested Election Case.

WASHINGTON. Feb. 1.-The contested
election case of Davidson (Rep) VS. Gil
bert Dem.), for the Eighth district of
Kentucky, was heard today by House
Election Committee No. l. Mr. Yorkes,
counsel for Davidson, referred incidental
~ to the present critical situation in
Kentucky, and said that owing to this
he would refrain from referring to the
Goebel election law, as he had Intended
The issue in this case turns on the con-
stitutionality of the law redistricting the
Eighth Kentucky district
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
Spanish War Veteran.

Private humans, of Company B Sioux
Falls, First regiment, South Dakota
volunteers, has arrived at Hot Springs
from his home at Sioux Falls, to enter
the state soldiers home at this place.
humans is the first veteran of the Span
ish-American-Phil war to apply for
admission to the home. His health was
fatally undermined by his Philippine
campaign, and he is almost a total
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
Receipts and Expenditures.

WASHINGTON. Feb 1.-The compare
tive statement of the government receipts
and expenditures issued today shows that
ceipts from all sources amounted to s4S.-
OH 164, against Sal, 774,9S0 for January, 1899
The expenditures during the last month
aggregated S39.1S9, 096, against So, 122, TO
for January, 1889, leaving a surplus last
month Of IS, S23.06S
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
Remidii Is Growing.

BEMIDJI, Feb. 1.-eS-ecial)-A meet
ing of citizens has been held for the pur-
pose of talking over the matter of or
grown to population of upwards Of
1000, with many diverse interests that.
demand ward representation in the coun-
ell. One of the objects sought to be ac-
complished also is separate assessment
and election districts, the village at pres
ent being a part of the town of Bemidji
for those purposes. bar association
for Beltrami county was also put on
foot, and an association banquet provided
for Lincoln's birthday.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02

Moore, of Deadwood, will appoint re-
soon as both parties concerned can agree
upon a person. There are two mortgages
against the water works. the first one
amounting to about s5o,6OO which is held
second of about $4,000, held by Dir. D. K.
Dickinson. of Lead The; request for re-
ceiver was made by the holder of the
second mortgage.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
Too Much Hilarity.

FERGUS FALLS, Mimi, Feb. IA.
Shaw was found lying in the road about
two miles from New York Mills Tuesday
morning, with his hands, feet and other
portions of his body badly frozen, and
all the fingers except two chewed off his
hands. He had been celebrating in New
York Mills the night before, and on start
ing for home had lost his way. He was
brought to town ana was taken to the
Soldiers home, where he will he cared
for In the future
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
LISTENED TO MIR. sIBLEY.
House Made Little Progress With
business in Hand.

House Made Little Progress With
Business in Hand.
WASHINGTON, Feb. 1.--Repress ntanve
Joseph Sibley, of Pennsylva-lia, who at
tanned great prominence in the Fifty
fourth congress by his earnest champion
ship of free silver, assailed his Demo-
cratic colleagues today for their opposl-
ton to expansion in a speech that made
the floors and galleries roar.
Mr.. Sibley has recanted his views on
free silver, and is now generally out Of
line with his colleagues on the Democrat
ic side. He insisted today that expansion
was an original Democratic doctrine, pro-
Ynulgated by Jefferson and adhered to by
Madison, Jackson, Tyler, Polk and Bu-
chanan In eloquent language he pictured
the destiny of the United States carrying
the arts of peace and tie story of the
cross to the remotest cuTners of the globe.
Mr.. Sibley received an Impressive dem
onstration when he closed.
The remainder ofahe debate today was
uninteresting. 1t Wudaed the questions
of mediation In the. Transvaal war, lynch
ings in the Souths apd the jury law in
Hawaii Not muchs prpgress was made
with the Indian appropriation bill, which
was under consideSatien.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
Fell Down the SHAFT.

Robert Rowlend fell one story down an
elevator shaft in new block at 622
Hennepin avenue about 10 o'clock last
night while at work with two other men
in the building. The three We're trying
to work by candle light, and in the dark
ness Rowend stumbled into the open
elevator shaft, in which the elevator had
not yet been placed. and fell to the base
ment. The police were called and took
him to the city hospital, where 1t was
found that he had sustained a scalp
wound. lie also seemed to be internally
In jllred
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
Sidewalks Wanted.

WINoNA, Minn.,a Feb. 1.-(special)-
Orders are now being issued to some sew
enty-five property owners instructing
them to lay sidewalks in front of their
property. Some two miles of stone walk
are included, bringing, the probable cost
for more walks is expected shortly. A
5000 damage suit recently suffered by
the city by reason Of "a defective walk is
the cause. ~
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
whale Family Aspbyx,a,aa

NOBLESVILLE, Ind, Feb. Mrs
Samuel W. Thurman, aged sixty and
daughter, aged seventeen, were asphyx-
lated by natural gas at Sheridan today
When found the mother and daughter
were dead, and Mr.; Thurman was ~
hand. During the night the fire had
gone out and the gas escaped. Thur
man tried to shut it off but fell uncon-
scious He cannot recover
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
De,uocrat Removed.

WINoNA, Mimi. Feb 1.-(Special)-
Under orders received from the depart
ment yesterday F. c. Summers, a Demo-
GRAFT and for Longtime janitor of the
federal building. was removed, and D. c.
Martin, a prominent local Republican, in
stalled in his place. Summers removal
was secured by Postmaster Gartside, who
brought charges against him.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
WHAT Do The CHILDREN DRlaK2

Don't give them tea or coffee. Have you
tried the new food drink called GRAIN-O?
1t Is delicious and nourlshng and takes
the place of coffee. The more Grain-O
you give the children the more health you
distribute through their systems Grain-O
Is made of pure grains. and when prop
erly prepared tastes like the choice grades
OF coffee bur costs about " as much All
grocers sell It, 15c and Csc.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
Philippine Report In.

WASHINGTON, Feb. 1.-The members
of the Philippine commission, Messrs:
Schurman, DENLY and Admiral Dewey
with Secretary Macarthur, called at the
White house late this afternoon and
handed their report to the president 1t
is understood the report will be sent to
congress within day or two.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
January Coinare.

WASHINGTON, Feb. 1.-The monthly
statement Of the comptroller of the cur
rency shows that the coinage executed
at the minis of the United States during
January, 1900 amounted to s14,05 431, as
follows: Gold, $l1.515 900; silver, 81, 3S4 161 ;
minor coins, $174,270.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
WEBSTER THREATENS SUIT.
Former Alderman Thrown From His
Rig and Injured.

e. e. Webster, who ran against James
Gray for mayor, threatens to bring suit
for damage against the city as result
of injuries received in an accident. While
driving home a few nights ago his vehi-
Gle struck huge block of ice which was
in the middle of the road near Lake Cal
houn. He was thrown from his rig and
sustained confusion of the shoulder,
which was dislocated. He claims the ice
was allowed TO remain in the road
through carelessness.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
Dodge Center Notes.

DOGE CENTER, Mimi, Feb. 1.--R. r.
Ashland township, was buried Tuesday
He was lifelong resident of this place
and one of the prominent members of the
Seventh Day Baptist church. Mrs. A. H
Van Kirk died early yesterday morning
after lingering illness.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
IOWA ELECTION LAWS,
Titus Bill Has Passed Both Legisla-

Titus Bill Has PASSED. BOth Lesis1a-
tive Houses.
DIES MONIES, Feb. 1.-The Titus ben
NAL election bill passed the lower house
today by a vote of eighty-five to seven,
and is now ready for the signature of the
governor. The bill revolut.onizes the hold
ing of elections in Iowa, its chief provis
ion doing away with the holding Of annu-
al elections. The measure for constltu-
tional amendment will be submitted to
the people at the next general election,
and II approved, will go into operation.
The amendment has now passed through
two sessions of the legislature
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
Cuba Census Firure..

WASHINGTON, Feb. 1.-The details by
the gross population of Cuba have been
announced by Gen. J. p Sanger, in
charge of the census taking, as follows:
Pinar del Rio, 1862 Havana, 44.S11:
Matanzas. 202, 1852; Santa Clara $50. 537:
Puerto Principe, 1921; Santiago, 327,716;
total SIP $40
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
Freight Train Wrecked.

BARABOO, Wis. Feb. la freight
train running at full speed on the North
narrows a -Ablemans last night and was
badly wrecked. Engineer Jacquish, Fire
man Fred True and Brakeman Frank
McGarr were seriously hurt. Jacquish is
not expected to recover.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
Joke ON Gen. Ludlow.

HAVANA, Feb. .1.-Gen. Ludlow, the
military governor, today received a sum-
mons issued by the judge of the munic-
ipal court, on the application of the man
publishing an injurious letter. In defer
ence to the law, he sent an answer to
the judge declaring that all he had said
in the letter to the New York Times was
true, and that he had nothing further to
say in response to the summons. He
regards the whole matter as farce.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
New GOMEZ DISCOVERED.

CAMBRIDGE, Mass, Feb IA dis
patch has been received at Harvard coll
lege observatory from Prof. Kreutz, at
was discovered by Giacobindi at Nice, Jan.
81, 292 Greenwich mean time in r.. H.,
81 MIN, "A sec; dec, I deg, 81 min.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
THREE ARE INJURED.
Rock Falls Onto n Railroad Track
and Wrecks Train.

BARABOO, Wis, Feb. 1-{Special.)-A
large quartz rock became dislodged ana
fell onto the Chicago & North Western
track, wrecking a freight train. Frank
Jaquish, engineer; Fred True, fireman.
and Frank McGirr, fireman, were all
more or less injured. Frost disclosed the
rock and it had TO be blasted from the
track.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
Case of Cant. Carter.

WASHINGTON. Feb. 1.-The papers in
the case Of Capt. Carter We're received at
the supreme court today. The applica-
ton for a writ of certiorari will have
to be made Monday.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
Charged with Robbery.

Paul Bordeau, young man Of seven
teen, who emphatically protests his inno-
cence, was arrested early last evening
charged with highway robbery. The vic
tim, anthony Myers, was also locked i. up !,
drunkenness, to be held as witness. 1t
is claimed that Bordeau and companion
were robbng Myers in Tenderloin alley.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
To Investigate Finances.

WINNIPEG, Man, Feb. Premier Mac
donald has appointed Bartlett, manager
of the Hamilton bank; Kennedy, man
ager of the Bank of Nova Scotia, and
Reeve Halse commission to investigate
the finances of Manitoba.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
Shipping Bill Hearing closed

WASHINGTON, Feb. 1.-The hearings
on the shipping bill were closed before
the house committee on merchant ma
rine today and 1t was arranged to pro-
coed with the executive consideration Of
the bill next Thursday.
The Saint Paul globe. (St. Paul, Minn.) 1896-1905, 1900-02-02
DEATHS OF A DAY.

ROME. Feb 1:-Cardinal Vicar D. NJ
Jacobini formerly papal nuncio at Lis
bon, Is dead. He was sixty-three years
of age, and received the red hat in 1886.
LA CROSSE. Wis. Feb. George L.
Kingsley Sr. died here early this morn
ing, after long Illness, of Brights dis
ease. He came here in 1872 from Mich
igan, and has since been engaged In the
numbering busti1ess.z~sI 1ess leaves a wife
and three children. He was appointed
second assistant engineer I'M the navy on
temporary services In August, 1854, on
U. S. s. Chiilicothe, and served year.
ST. LOUIS, Feb. 1.-Former Congress-
man r. Graham Frost died this afternoon
at the residence of his father, Gen. d.
M. Frost. He had been Ill more than a
year with Bright's disease.