The times. [volume] (Richmond, Va.) 1890-1903, 1900-12-30
one mid case Second day. six days be-

one Hlllu case lSecOllu QdS) SIX DAYS DC
fore.
1t viii be seen that X. Y. was bitten by
four mosquitoes, two of which had bitten
severe tataD cases of yellow fever
twelve days previously: one of which had
bitten a severe case Second day) sixteen
days before, and one which had bitten d
severe case eight days before.
Y. y. began to experience sense of diz-
ziness and dissemination to work. This
was just five days from the time OF the
mosquito ejaculation; twenty-four hours
later ne was Still dizzy and lisht-headcd
in attempting to move about. During the
afternoon Sixth day after inocluatiom
he had chilly sensations, followed by fever
and restlessness during the night.
On the following day Seventh day aft
ter inoculation). s A NJ. temperature was
1928 degrees Fahrenheit, his eyes were
slightly injected and his face suffused.
The patient was removed to the yellow
fever wards; at A. NJ. temperature was
1O3 degrees Fahrenheit; pulse, Sc. The
conjunctivae were slightly jaundiced on
the fourth day of the disease, which was
more distinct and could be plainly seen
on the anterior aspect of the chest on the
fifth and following days. Bleeding from
the gums was noticed on the third and
subsequent days after admission. Repeated
examinations of the blood failed to show
any malarial parasites.
The course of the fever, the appearance
of albumen in the urine, with jaundicc
and hemorrhage from the gums, together
with the slow pulse. all pointed distinctly
to the diagnosis of yellow fever His
attending physician, DR.. Roger P. Ames.
u s. A, an expert in the diaSosiS and
treatment of this disease, did not hesitate
10 diagnose n Us attack as one Of well
pronounced yellow fever" DR.. Ames was
not cognizant of the method of inocula-
ton in this case.
In the light of these two cases we con-
slider that of DR.. Lazear Of sufficient i'm
portance to be here included, especially
as it is one that might be possibly desiS-
mated as a case Of accidental infection by
a mosquito.
Dr. Jesse W Lazear. acting assistant
surgeon United States army, a member
of this board, was bitten on August 18th,
1900, by a mosquito (Culex fasciatus)
which ten days previously had been con-
taminated by biting very mild case of
yellow fever (fiftl day.. NO nppreciabe
disturbance of health followed this inocu-
iatiOn
On September 18Th (forenoon), DR.. Laz-
ear. while on visit to Las AnimaS Hos
pital. and while collecting blood from
yellow fever patients for study, was bit
ten by a Culex mosquito variety undeter-
nined). las DR.. IaZear had been previous
ly bitten by a contaminated insect without
after effects, he deliberately allowed this
particular mosquito. which had settled on
the back of his hand, to remain until it
had satisfied its hunger.
On the evening of September 18th Give
days after his bite, Dr. Lazear complained
Of feeling "out of Sorts and had Il chill
at P. NJ.
On September 10th, 70 o'clock, noon, his
temperature was 1921 degrees. pulse 112;
his eyes We're injected and his face SUI
fused: at 3 P. M temperature was 1884
degrees: pulse, 104; 2. NJ. temperature
1858 degrees and pulse Jog. Jaundice ap-
peared on the third day. The subsequent
history of this case was one of progressive
and fatal yellow fever. the death of our
mudl-lamented colleague having occurred
on the evening Of September 25th. 1900
As DR.. LaZear was bitten by a mos
quito while present in the wards OF 4
yellow fever HOSPITAL. one must. at least,
admit the possibility of this insect con-
tam!nation by u previous bite OF a yell
low fever patient.