The Dupuyer acantha. [volume] (Dupuyer, Mont.) 1894-1904, 1899-02-23

In some experiments carried on by
the Minnesota Experiment Station the
following conclusions seemed to be
warranted:
4. Tuberculin by hypodermic injec-
ton is SO accurate as a diagnostic agent
for bovine tuberculosis as to be thor
oughly practical.
2. Tuberculin may fail to indicate the
presence of tuberculosis in cases where
the disease changes are advanced and
general.
8. Tuberculin by hypodermic injec-
tion is not injurious to the health OF
sound cattle, even in very large doses.
A. Tuberculin by hypodermic injec-
tion is not injurious to the health OF
tuberculous cattle, in doses Of bureau
tuberculin) from n cubic centimeter
per 500 pounds live weight, which is
the ordinary test dose, up to one cubic
centimeter per $50 pounds, which
would be an unreasonably large dose
for either diagnosis or treatment.
s.. Cattle sometimes fail to react after
n or several injections. In such
cases cures may have been effected or
the animals may have become insus-
ceptible to the agent and may still re-
main infectious.
6. 1t is evident that an animal nay
remain t~uberculous and infectious after
several injections of tuberculin or be
badly diseased and yet refuse to react.
Z. The diagnostic value of retests. is
therefore much less than the first and
such subsequent tests must be consid-
cred inaccurate.
8. OF those which showed extensive
disease of the lungs and attached
glands, about 70 per cent gave a dis
tinct rise of temperature within ten
hours and a maximum of S.5 degrees or
over. Conversely, of those which gave
a distinct rise of temperature within
ten hours and a maximum of 3.5 de-
grees or over, about 70 per cent showed
extensive disease of the lungs and at
tached glands when Bureau tuberculin
was used in doses of n cubic cent?
meter per 500 pounds live weight. Due
care was exercised as to time of water
ing, temperature of stable, exercise,
nervous excitement and the various
factors which may influence the tenn
perature of the animals undergoing
test.
1t has also been frequently no.
ticed, but may not hold true, when
larger statistics are shown, that ami
mails which are extensively diseased
and especially if the LESSONS were of
long standing, often give low reactions
or none at all.
8. The tuberculin test may be uncer-
tain but not otherwise Objectionable in
cases of advanced ~pregnancies.
10. Tuberculin may have a distinctly
curative effect in cases of recent in
lection or where the LESSONS are lin
eited in extent and it may increase the
tendency toward recovery in other
cases. Two cases made evident recov-
cries out of eleven treated. Two 9TH
ers showed evidence:fof recent repair
in diseased tissues.A
There were evidt 8tly two recoveries
and possibly a third out of eleven cases
treated during the whole period, and
treated under such other circumstances
of food and care as preclude the prob
ability of the r%ecoveries being favored
by the conditions under which the ami
mails were kept.
The general physicaE condition of all
the animals remained excellent
throughout the experiment. There was
no loss of condition in any case but in
several a decided gain in spite of the
ordinary food and Indifferent care
which were purposely given.