The Indianapolis journal. [volume] (Indianapolis [Ind.]) 1867-1904, 1895-01-28

be cured, demand that nature shall build
now tissues to fill the gaps. But that sero-
ally feel positive.
ssNone Of the improvements can be as
nearly every case against the viii of the
patients that we injected them. For four
weeks or more, the cases at the City Hos
ptal fought and objected and 1t was on'y
after realizing themselves the benefits that
they submit gracefully.
These results surely point to a decided
ly favorable ground to hope for more sue
cess IT, In such short time, under sucn
circumstances and in such surroundings,
pltaI one can put flesh and fat on a con-
sumptiye, while untreated witness cases,
under the same conditions, continually fail.
what may We hope IL consumpttves IN the
first and second stages. at least, are placed
In a modern sanitarium, or kept In their
homes even, and surrounded by all the
cares that increase good health and the
conditions for the rich reconstructive diet
that should be granted such unfortunates?
furthermore. all the sanitary conditions
that may aid nature to cure or arrest
tuberculosis in any event?
"All of these records were kept accurate
ly by the physicians and nurses in charge
of the cases at the Slty Hospital and
by pr S, Gale physician In charge Of the
l secured, chiefly to act as witness physi-
clan, as soon as l had gained the idea
that j was in possession of blood serum,
truly useful for the purpose intended. Dr.
Gale was selected because of his qualifi-
cations in microscopy and surgery, ac-
complishments. required in a man whose
help II was thought desirable and policy
to employ to verify t4.e diagnosis of each
case microscopically and to give an opinion
on surgical cases of tuberculosis, which
then wished to secure for experiment. The
sputum of every case treated contained
the bacilli of tuberculosis before we be-.
gan. DIR. Gale mounted specimens from
each and he and l examined every one
Of them, The sputum was again analyzsd
results above explained. All mounts have
been labeled and kept for future refer
ence At. the City Hospital, after the in
auguraton of the treatment, the immediate
supervision of the injections and attend
ance was by DR.. Enrich, who did his duty
carefully and conscientiously. Mrs. John
son, very competent woman, in
charge nurse
Blanks worded as. the sample shown
you were used. blank being for the
daily reports and blank for the history,
nature, ETC., of each case and the compia-
ton of the daily records at the end of each
month. And SO, for each case every pre-
caution was taken that seemed necessary
to insure. reliable records and to convince
the medical profession Of the truth Of
the facts reported.
PREPARATION OF THE SERUM
BY the use of the proper toxins gradu-
ally rendered a couple of horses more
strongly refractory to the action of the
germ than they are naturally. Immuniza-
ton was carried on with the assistance
of deputy veterinarian, DIR. Roulf of
this city. who had previously kept the
horses under surveillance and had exam
med and tested them carefully with me.
and independently, until we had convinced
ourselves of their healthfulness. He did
his work admirably.
Having immunized horses and tested the
serum by experimental processes and noted
It's effects on animals, and having injected
1t in myself to determine its reaction, 1t be-
came necessary to procure a number of
ms iny1f- t< fncA &C.
man consumption. With this object in view
| secured from DR.. Holman, Health Com
cases at the poor house for reatment, and
also secured from DR.. Marks. superintend-
ent Of the City Hospital. leave to try the
remedy In that institution. Both of these
officials have been very kind. and entered
into the scheme of tests with genuine
scientific spirit. They turned over to me
and my colleagues all the cases we wanted
and expressed their good will in many ways
| owe them my sincere thanks, for their
generous assistance. and under obliga-
tons TO them. as also tc the physicians of
the Door house.
1.-The treatment began with injections of
ten drops hypodermically in the back be-
tween the shoulder blades. In few days
we increased to twenty drops. Then to
thirty, forty and sixty. Some were given as
MANY as seventy drops once a day for a
while. To few in private practice have
injected as much as $50 drops at one sitting
every day for several DAYS. No reaction
whatever followed these infections, and the
pain is no greater than during the usual in
suited no accidents whatever from over
total of 1870 injections in the various pa
t .1ent h,, except at the lily mosptal where
| cur sometimes after other kinds of injec-
| tens under the skin. They were without
doubt due to micro-organisms in the sv-
ringe. probably on the leather ends of the
niston of the syringe used at the time, or
| IN the needle Careful d,ssnfection of the
syringe will ALWAYS prevent this occurrence
The serum Is. IN fact, innocuous, absolutely
| so, If we'll prepared.
PROSPECTS OF SERO-THERAPY.
1.-THE future of the serum therapy in sew
eral infectious diseases is assured beyond
| peradventure. We may have been too en-
| thusiastic, and may have expected more
| than we can obtain perhaps, and possibly
| the enthusiasts may be painfully disap-
| pointed in their hopes of immediate Won
| ders from the sero-therapy in dphtheria,
| tetanus, ETC., but the fact will always re-
| main that this system is unquestionably ra-
| tional, and eventually 1t must yield success,
in therapeutics where all else must fall for
| it Is the one rational truly physiological
| treatment the only treatment in my hum
/ BILE judgment from which can be derived
| positive beneficial results In the cure of in
| fections 1t is natures own remedy Man
| with the serum is using natures own
weapon aof defense; he has found out how
| he may add power to the natural resources
| of the organizaton in the fight for human
eXistnce. This system of treatment is not a
| spontaneous Eruption in therapeutics. 1t is
| not in the explosion of enthusiasm in over
! jealous laboratory delivers with more theory
/ than experience; it is the result of years of
| research in all the laborat tories and in
| chief clinics of the civilized nations, par
| ticularly France and Germany. And il is
| not only yesterday that ii appeared in prac-
| tice. 1t was several years ago that Kitas
| sato applied his anti-toxne successfully
| against tetanus. Diphtheria has been sue
| cessfuly treated year more. Syphilis is
| now treated eXperinentaily with it, and
| lastly, your humble servant begs to submit
| to your indugent criticism the result of his
| meager labors, conducted under extreme d f.
| ficulties without State anv financial aid
| when these were most needed that Isl. par
| ticularly during the applications and ex-
| periments OF the last two years. The future
| of sero-therapv In tuberculosis is in nv
] mind, very bright and very PROMISING TIL
| first and second stages of CONSUMPTION have
| been benefited under unfayorable circurn-
| stances by even slightly immunzed serum
| Consequently. it is only fair to reason that
| with more strongly inmunized serum such
| as have now ready to use Il have ONLY a
| limited quantity, much better and quicker
| results can be obtained. particularly il
| prooer hygsenic and detetic condit' ons ara
| obtained. Theoretically it would seem that
| If by the use of this serum constituti on lly
| the tuberculous processes NAV be arrested
| in n given case. injections directly in the
/ pulmonary cavities where these exist OIL
| the eNciSion Of a rib two in the use o.
| tuhercle anti-toxina directly into the wound
| or perhsns some other antiseutfc mad'ca.
| ton, would nrove practica BILE and useful te
| H.