New-York tribune., 1895-01-11
THE ANTITOXIN TREATMENT.
PROCESS or INocULATIoN AND EFFECTS OF THE
SERUM DESCRIBED BY DIR. KINYOUN, OF
TIE MARINE HOSPIrAL SERVICE.

PROCESS or INOcELAT1ON AND EFFECTS OF THE
SERUM DESCRIBED BY DIR. KINYoUN. OF
THE MARINE HOSPITAL SERVICE.
Washington Jan. fO.-surgeon J. j. Kinyoun. Of
the United States Marine Hospital Service, who
was the representative of this Government at the
recent international Medical Congress In Paris,
after which he visited all the principal hospitals
and medical laboratories in France and Germany.
making n thorough study OF the antitoxin treat
mont delivered an address before the medical fra
ternity of Washington last night. in which he de-
scribed the process Of inocuaton as follows
A culture of the dphtheria bacillus was taken
from the throat Of child and put into peer
bouillon. in which it grew and with some Of this
material a horse was nocuated By a gradual
course OF treatment the animal vas INJURED 20 sne
OF the antitoxin neutralize the effects OF all the
diphtheritic poison. This blood. or at least rs
serum drawn off into sterilized tubes. was the
'antitoxin" OF the new dphtheria treatment. Dr.
KnySun said thai ne The ,s er sbnrt OF
In cases Of plain. uncompcated diphtheria the
MORTALITY G nothing BY far the greater number OF
cases, however were complicated, and in these,
from 10 per cent to less than 20 per cent.
Since the discovery Of the diphtheria oacius
scope SEQ was possible. the germ being as distinctive
as that Of tuberculosis. The speaker said that ss
were real dphtheria. No one by a Superficial ex.
animation can tell the two diseases apart; ekeeps
has caused the dissolution Of the membranes 20
immediate family and of the community, every phy-'
sician ought 10 resort at once to the microscopes
to settle the question in any suspicious case Inc
efficacy OF the treatment, the speaker said.
had been established beyond question ana Win @ tne
aid of this treatment TO combat the disease anu
thorough disnfection afterward. there was no rea-
son why the disease should not be stamped OUT en-
tirely. There was no question tnat tne uisSo.siy
of the antitoxin treatment was on par with tnat
of smallpox vaccination but it must be scentircaliy
handled by who understand the nature OF
the disease and its remedy. ana serum or STANDARD
strength must be used the best results cannot
be expected.
DR. Kinyoun said that he was in favor OF govern
mental municipal control. or az least supervisor
of the manufacture OF the antitoxin TO insure It's
being OF standard quality. Tne fact that Germany
was advancing the price of the preparation by 81
AT time. I'm spite OF the small cost or production,
money in il for Americans. \ short time would SEE
many brands of the preparation on the market
and there ought to be some provision FOR MAINTAIN
ing them OF uniform strength ana exceilence
that il will keep indefinitely. The French say ina
1t deteriorates after eight months but DR.. kinyour
thought that ii began TO change perceptibly In
much less time than that. so that the Govern
ment's supervision should include the date or manu-
facturc well : the strength.
Consu-Cieneral Mason has sent TO the state De
partment exhaustive report describing the manu-
facture OF antitoxin at Hoechst. near Frankfort
on the NIain which is the only establishment at
which the new specific for diphthera has yet been
produced commercially and in quantities adequate
to meet the rapidly increasing demand rms lac
tory is now producing over 1000 doses day. The
repor, was intended for the use of Congress In
case that body considered the subject
President Wilson OF the Board of Health said
yesterday that pathOlogst and five more assist
ants for the Bacterioogical Department were to be
engaged They will be employed in developing ana
manufacturers antitoXn. Their "a. aries Will be
81 200 year. but they will be obliged 10 pass Civl
Service examinations