The Yellowstone journal. [volume] (Miles City, Mont.) 1893-1901, 1893-09-21


treated as such. for through the almost
ceaseless activity of the German chem
lists enough new remedies have already
been obtained from coal tar to fill a good
sized pharmacopGia.
About the first one Of these products
to attract any considerable attention was
antipyrine, which made its appearance
some 10 years ago and became popular
ly known during the epidemic of la
grippe of several years ago. This was
soon followed by antifebrin, which, al
though it had a new name, was an older
drug than antipyrine, having been
known for several years as acetanilid, a
name derived from the substances from
which it was made. It is prepared by
the action of acetic acid on aniline oil.
The a~cetanilid is now used by many
doctors in preference to antipyrine. The
principal features in its favor are small
ness of dose, less danger of depressing
effect or the heart and chespness. The
pr1ce Of acetanilid il hardly one-tenth
Of antipyrine.
Phenacetine is another drug Of this
class which has met with much success
and apparently deservedly so. It has
been used with excellent results in the
treatment of influenza. the hyper@sthe-
STA or soreness of la grippe and rheuma-
tism. both muscular and %articular.
The drug is often combined with salol
and q~uinine in the treatment of the above
mentioned affections, and the results re-
ported are invariably of a very satisfac-
tory nature.
One Of the most interesting of the coal
tar derivatives is saccharin, a substance
that is 2sO times sweeter than sugar. The
medicinal properties of this drug are IN
tiseptic and sw~eetening. AS a substi-
tute for sugar it is used in the dietary
of govt, diabetes and all diseases in
which saccharine foods are contraindi-
Gated. 1t has also been used to disguise
the taste of medicines for children. To
give one an idea of the sweetening power
of saccharin it is only necessary to say
that one grain of the drug will sweeten
an ordinary cup Of coffee. If sugar We're
used at least a half ounce or a table.
spoonful, would be necessary.
In the treatment of mental disease sui
phonal is considered a very valuable
agent. The drug could hardly have
achieved success had it peer introduced
under its chemical name, which contains
just two letters more han the entire al
phabet. Observation-Disclosures
is the ''jawbreaker' by which, it is known
technically.
The value of sulphonal as a hypnotic
seems to be pretty well established. 1t
has been. used with marked success in
the treatment Of sleeplessness caused by
fatigue and worry. 1t is also said to he
of equal service in cases of acute mania.
imhecility, melancholia, dementia. cpl
lepsy, Authorizations and acute alcohol
ism. One observer stated that in every
case treated 1.-The slumber was accom-
panied by no disturbances of circulation
or respiration and lasted from two to
five hours or longer" From Is to so
grains are usually given as a dose. Even
in very large doses the digestive func-
tons are not disordered, and there are no
disagreeable after effects beyond "A slight
drowsiness and a feeling of lassitude the
next day.
In combination with hyoscine hydro
bromate. sulphonal is said to form a very
good treatment for the insomnia and
restlessness of opium habitues. When a
coal tar product is introduced, it can al
most be taken for granted that one of the
four medicinal properties is claimed for
1t. The four properties are antipyretic,
analgesic, ~antiseptic and hypnotic.
Trrona1 0ybich hoi1a fro~ E1lo-co1l
Germany, is brought forward as a candi-
date for therapeutic favor. 1t possesses
the last named property. Brie Of Bonn
has found trional Of value in treating in
or hysteria and neurasthenia in
cases of great obstinacy and which had
failed to respond to any other treatment.
In maniacal excitement and paralytic
mania, he reports excellent results in 90
per cent Of the cases treated.
Salophen, although not distinctly a
coal tar derivative," is partly SO, as one
Of its component parts, carbolic acid, is
derived from coal tar. 1t is said to be a
valuable remedy in the treatment of ar
rheumatism. The dose is from
to 20 grains three or four times a day.
The very latest in the long line of coal
tar products is gallanol. 1t is prepared
by boiling tannin with aniline. 1t is in
PRODUCED as a substitute for pyrogallic
acid, having the advantage Of being non
and nonirritant. In the treatment
Of skin affections it has been used with
C~azeneuve, the introducer Of the drug,
great success in treating psoria-
rs by painting the spots with gallanol
suspended in chloroform and covering
Them with a solution of gutta purcha in
called traumaticin. New
York World.
ChOkes, Not Jokes.
Don't send the horse reporter to any |
more hangings." said the proprietor of a
Texas paper to the managing editor