Pittsburg dispatch. [volume] (Pittsburg [Pa.]) 1880-1923, 1892-08-31
CHOLERA VACCINE.
A Product of the Pasteur Institute Explain.
ed by Its Discoverer.

A Product of the Pasteur Institute Explain-
ed by Its Discoverer.
From the Paris Figaro.l
A fact of the highest importance from
scientific point of view has just been brought
to light in the Pasteur Institute of Paris. M
Haffkine q learned biologist, declares that
he has discovered vaccination for cholera.
One may imagine the commotion that the
announcement of such q discovery causes in
the medical world just now.
The Figaro reporter found M. Haffkine ex-
perimenting with his cholera virus upon two
guinea pigs "With two injections" said
the biologist, "they are made proof against
all attacks of cholera We have repeated
the experiment several times. The method
is very simple. If inject cholera virus into
the animals that have been vaccinated they
suffer no trouble whatever; but when i do
the same thing to an animal not vaccinated.
it is pretty sure to die with all the symptoms
of cholera. The animals that are not vacct-
mated we call witnesses"
Reporter-It 1t might be good thing to try
the experiment upon men.
NJ Haffkine-It has already been made, at
least one part OF it. OF course it wouldn's
do to try the other part. 1t would hardly
be the proper thing to fnoculate human
witness" with colera virus to see If he
would die. But four of us, DR.. Tamanchen,
my friend, NJ. Wilbouchevitch, and myself,
have been injected with the cholera vac-
cine.
Reporter-And you believe tnat you are
proof against cholera7
NJ. Hafkine-I am convinced of it. be-
lieve In my discovery because have made
great many experiments upon animals.
Reporter-Where do you propose to COM
mence the application OF your method'
M. Harkine-In Russia. As you know,
am myself Russian, and. considering the
q Pnidamic h4a
my country; i will find there a consider.
able field of operation. have already made
offers to the Russian Government, and I
have just received letter from DR.. Reme-
soft, who left here few weeks ago for Mos
cow, taking with him quantity of virus.
He tells me that he has inoculated himself
and several of his colleagues. They have
noticed exactly the same symptoms that we
have experienced.
Reporter-What are those symptoms?
NJ. Haffkine-After the vaccination we feel
a feverish indisposition with headache and
dryness Of the mouth. That remains day
or two, but the local pain in the tissues re-
mains little longer. And, strange enough,
the symptoms are like a light attack OF in
fiuenza. 1t is not the first time that we have
noticed a connection between cholera and
influenza
doctors who have discovered vaccine for
cholera?
NJ Haffkine-In Germany several savants
of the Koch school have been making some
interesting experiments, NJ brlo5er espeCt-
ally; but his method of injection in the peri
toneum is so dangerous that don't think it
can be applied to man. My discovery is in
some sense French discovery, although 1
have not the honor of being a Frenchman;
but 1t has come out under the auspices OF
the Pasteur Institute, and it constitutes
new application of the general methods OF
exhalatlon and attenuation OF the viruses,
methods which are due entirely to M. Pas
teur. 1t is to him and to NJ. Roux, whose
aid has been most precious for me, that the
larger portion of the merits OF this discovery
belongs.