, 1890-11-20
THE SECRET NOT OUT.
Not Ready to Tell How the
Cure Is Made.
CHARACTER OF THE LYMPH
Also Where II May Be Obtained,
and Manner of Applying the
Medicine.

BERLIN, Nov. 1f.---Professor Koch pub
fishes an article In Deutsche Madiniziche
Wochenschrift for the euro of tubercu-
losis. Professor Koch says he Is yet un-
prepared to indicate the source from
which the curative matter Is derived and
the method of preparation, for the rea-
son that experiment work Is still in
progress. lie states that the curative
lymph itself can be- obtained from DIR.
Libbertz, address No. % Lueneburger
Strasse, Berlin. The lymph is described
as consisting of u brownish transparent
liquid, so prepared as to be proof against
deterioration, when diluted with water
for use. The matter Is liable to decay.
Ii is necessary, therefore, that the atten-
uations be perfectly sterilized by heat
and preserved In wadding covering or
prepared with a solution OF phenol %
per cent. strong. When taken into the
stomach the curative matter 10 have
effect must be applied simultaneously
by means of n yalvelcss syringe, which
should be rinsed with absolute alcoho oil
and kept in n perfectly aseptic condi-
tion.
Twenty five hundredths OF a cubic
centimeter intensely affected n healthy
man, who was subjected to the expert
ment while two cubic centimeters ap-
piled to guinea pig had little effect.
Professor Koch injected twenty-five
hundredths cubic centimoters under the
skin of his own arm and within few
hours experienced contraction OF tho
Limos and marked feeling CT lassituce.
At the same time he felt u desire to
cough, together with difficulty Of breath
ing. These symptoms increased rapid
ly, and In live hours he experienced an
unusually violent rigor, accompanied
with nausea and the temperature of
the symptoms began to abate and the
next day his body resumed
its normal degree. The heavinoss
of the limbs and the languid
feeling continued for several days, how
ever The same results follow when tho
fluid is applied to diseased persons suf-
fering from other than tuberculosis af-
tections, but in persons affected with
tuberculosis the same quantity produces
strong general and local reaction. The
reaction can best be observed on those
whose affection is visible, as, for instance,
persons suffering from lubus. Within
few hours after the injection lupun
sores begin to swell, and finally assume
dark brown tint. After the fever sub
sides the swelling decreases and gener-
ally disappears, scabs of matter falling
oil later. The portions of the skin not
clearly recognize. as lubus are not af-
fected.
1t Is asserted, with confidence, that
the remedy may be considered an in
dispensablo auxiliary to diagnosis, and
in doubtful cases of incipient consump-
tion, can positively be diagnosed by its
use. Professor Koch expressed the
opinion that his remedy will certainly
prove cure for insipient consumption.
Whether, however. the cure be final and
definite is not clearly proved. Further
experiments are necessary to determine.
The remedy can only influence living
tuberculous tissue. 1t has no effect
whatever upon dead tissue, and produces
no effect upon tissues which have al
ready been killed by the application Of
the remedy. 1t is quite possible such
dead tissue may still contain living
tuberculous bacilli. which may again in.
wade adjacent living tissue.
1t follows, therefore, that tuberculous
tissue that 4, still living must be made
first to decay. When this has been ac-
complished every effort must be made
to remove the dead matter by surgery.
When this is impossible, and secretion
can only slowly proceed, the living tis-
sue must be protected by "a continued
application of the remedy. The remedy
f,, a
quantity at first sufiices to produce q
strong reaction, but as each succeeding
injection causes the disappearance of a
certain quantity OF tissue capable OF re-
action, increased doses are necessary
until the patient experiences rs litt.s
reaction as on-tuberculons people. Pa
tents who have been treated in tho
early stages of 'phthisic, have all been
freed from the morbid symptoms within
from four to six weeks, when they may
be regarded as healed.
Consumptives with largo cavities in
their lungs will probably experience a
benefit from the new remedy only in
exceptional cases. In all cases Professor
Koch emphasizes the necessity of early
treatment. Only In incipient stages of
the disease, he declares, can the remedy
fully develop its efficacy. lie deprsca,es
the mechanical and indiscriminats ap-
plication of the remedy. holding It pre-
ferable that the treatment should be
applied in clinical institutions, where
careful observation is possible.
Consumptives Going to Berlin.
BERLIN, Nov. 14.-There is a regular
exodus from Mediterranean shore of