The Wichita daily eagle. [volume] (Wichita, Kan.) 1890-1906, 1890-11-15
KOOHS REMEDY.
Interesting Facts in Regard to the New
Treatment for OonsumptiOn.

BERLIN, Nov. 14-The article by Prof.
Koch in this weeks number OF the
Deutsche Medizinische Wochen blatt, a
German medical weekly, is entitled FUR
ther communications on the cure OF tuber-
culosis, and experiments which Doctor
Libbertz and staff surgeon Pruhle per
formed relating thereto, under Prof..
Koch's direction" In this article Prof
Koch says that he is, as yet, unprepared
TO indicate the source from which the cur
ative matter is derived; neither is he ready
to explain the method of preparation.
The reason he gives Is, that the expert
mental work has not yet been brought TO
completion He states, however, that the
curative lymph itself can now be obtained
from DR. Libbertz, whose address Is No.
%. Luenenberger strasse, Berlin.
Professor Koch eXperimented with the
fluid upon his own body, and describes
the effects He injected twenty-five hun
dredths of a cubic centimeter of the fiuld
under the upper arm. Three or four hours
after this injection was made, he eXpe-
rienced a contraction of the limbs and a
marked feeling Of lassitude. At the same
time he felt a desire TO cough, together
with difficulty of breathing. These symp-
toms increased rapidly, and in the fifth
hour he experienced an unusually violent
rigOr. The shiveriug lasted for nearly an
hour. and was accompanied with a naus-
body rose to 1916 centigrade. After a
period Of twelve hours the symptoms be-
gan to abate, the temperature of the body
declined, and on the following day resumed
its normal degree The heavness Of the
limbs and the feeling Of lassitude, how
ever, continued for some days during
which time the point on his arm at which
the injection was made, continued 10 be
painful and remained red.
Thus, a second or local reaction pro-
duced by the injection Of the fluid In
patient suffering from tuberculosis can
best be observed in persons whose tuber-
culous affections are visible, as say, for
instance, in the case of persons suffering
from tuberculosis. The changes which
ensue in these cases show in a surprising
manner the specifically anti-tuberculous
effect of the remedy. Within a few hours
after an injection of the fluid the lupus
sores begin to swell and redden. During
the fever the patients experience is as al
ready described, the swelling and redden-
ing of the sores increase, until, finally, the
lupus tissue assumes in places dark
brown tint and a necrotlc condition.
After the subsistence Of the fever, the
swelling of the lupus sores gradually de
creaSes, and possibly disappears altogether
within two or three days Meanwhile,
however, the lupus centers have become
covered with an incrustaUion, formed by
exuding serum. which dries up as IL
reaches the air. These incrustatiOns
gradually form into scales, which fall of
after two or three weeks.
In all the experiments after the first in
jections if any tuberculous process exist !
ed in the body, the appearances already
described supervened. Absolutely no eX-
ceDtion was noted whenever a dose
amounting to one hundredth part of a
cubic centimeter of the substance had
l.. 1s..I col hsaI
lief that his remedy will certainly prove "A
cure for incipient phthisis. Whether,
however, the cure will be final and def
mite has not he says, been clearly proved.
Further experiments, and continued use
of the remedy will be necessary TO deter
mine this question.
The curative properties Of the new rem
edies, Prof Koch declares, are of still
greater importance for diagnosis What
the fluid kills is not the tubercular bacilli, |
but the tubercular tissue This fact indi- |
rates the well defined limits which the efii- /
racy of the remedy will be able TO reach. |
In other words, il can only influence liv
ing tuberculous tissue. II has no effect /
whatever upon dead tissue, such as de- (
cayed matter, necrotic bones and the like. /
More than this il produces no effect upon |
tissues which have already been killed by 4
the remedy. 1t is quite possible that such /
dead tissue may still contain living tuber T,
rulous bacilli These may then be expelled 1
with the necrotic tissue, or il may he that /
under special circumstances they may
n ain invade adjacent living tissues.
10 follows, therefore, that tuberculous |
tissue that is still living, must first be /
made to decay. When this has been ac- !
complshed, every effort must be made to I
remove the dead matter by surgery In 4
cases where this method is impossible. /
and secretion can only slowly proceed by /
the self help of the organism threat ened, /
the living tissue must at the same time be /
protected 10y continual application of the /
remedy. so as to guard against the re. |
immigration of the parasites. In all cases |
pf lupus 80 far treated. the amount of 1
Huid injected hes been, in the first in
stance. one hundredth part of "A cubic /
centimeter. Time hasthen been allowed for |
the reaction 10 take it's full course. After /
a period of from one TO two weeks, sec /
ond injection Of the same amount has /
been made. This treatment has contin- /
ued until the reaction grew weaker and /
finally ceased.
In two cases of lupus of the face, the sores, |
after three or four injections, became |
SCARED and presented n smooth surface. |
Each one OF these cases had suffered for |
many years. and had been treated by other !
methods without beneficial results. /
Persons suffering with tuberculosis of the |
Emphatic glands bones or joints have been |
treated with precisely the same success.
There has been rapid healing in the milder |
eases. ana cases Of recent development OF 4
the disease, while in sCverer cases the inn 4
provement. while slower. has been steady. 4
Patients with pronounced tuberculosis Of /
the lungs, have proved far more |
susceptible 10 the remedy than
those suffering with surgical tuber- .
cuar affections. Con sumptives have in /
almost every instance, manifested a strong
reaction on greatly reduced doses. With /
such patients therefore, a beginning should /
be made with doses of two woone-thouSaudths /
part of cubic centimeter or even with /
one one-thousandth part From this small 4
luCipient dose one can advance to such /
quantities as the patient can easily bear. /
In the experiments that have been con
Quoted CUuSumptIves have accordingly first
received subcutaueous injection OF one
one-thoUsandth part of a cubic Ceutime-
ter. Then, when the temperature Increased.
the same dose was applied daily until no
further reaction occurred. Thereupou the
dose was doubled, the ue-thouSsndth
parts Of cubic Centimeter being injected
regularly until again no reaction oc-
CURED.
This method was continued with almost
always au increase Of one One-thouSaudth
part OF a cubic centimeter, or almost two
one thousandths up 10 one one-huudredth /
part, and SO on upwards. In this way the /
patient would be brought to take very
high doses almost without fever, and al .
most impercepubly 10 himself Con /
sumptive patients who are still fairly ,
strong reach increased doses much more T.
quickly. and favorable results follow with 4
rapiGity. As general /
rule the coughing and expectorations arc
increased somewhat after the first iBlec-
tions. Then they become gradually f.
less, and in the most favorable cases \
will ultimately wholly disappear In the
cases experimental upon under the direc-