The Madison daily leader. [volume] (Madison, S.D.) 1890-current, 1890-11-18
The German Professor De-
soribes the Effect of the
Remedy on Himself.
He Believes the Same VIII Ger
tainly Prove Cure for In
oipient Phthisis.
An Important Decision Regarding
Swamp Lands---New Stock Yards
Company incorporated.


person, as well as experiments ON other sub
joets. The article says that when the cura-
tive matter IL applied 20 patient the usual
course IL To inject tt under the skin OF the
back, between the shoulder blades and In
proximity TO the lolns, The experiments
show that humsn beings are much more
| susceptible To the effect of the new sub
stance than are guinea pigs. which have
been largely used In the course af the In
yestieations. Two cubic centimetcrs OF the
fluid applied 10 guinea pig produeed lit
tie. II any. apparent effect. Twenty-Five
hundredtlls OF cubic centimeter. how
ever, intensely affected a healthy,
full grown man who was subjected
o. experiments. Prof. Koch expert
mented with the iluIa upon his own
body and describes the effect, He injected
e5+ioO Of cubic cehtimeser of the nuid
under the skin of his upper arm. Three or
four hours after this injection was ade he
| experienced a contraction rf the limbs and
q alarked feeling OF lassitude. Atthe same
| tiTne he felt desire 90 cough together with
| difficulty o9 breathing. These symptoms
increased rapidly, aud In the afth hoar he
experienced an unusually violent rigor.
| The shlvering lasted for nearly an hour and
was accompanied by nausea and vomiting.
Tho temperature Of his body rose 90 1910
centigrado. After period of twelve hours
the symptoms began to abate. the temper
attre of the body declined, and on the fol-
loving day resumed Its normal degree.
The heaviness Of the limbs and the feel
Ing of lassitude, however continued for
some days. durlng which time the
point un his arm at which
the iniectlon was made continued 10
be painful and remained red. The experI-
ments 80 far conducted show that the lowest
limit of effective strength of theihuid I'm
healthy human body Is Tooth of cubic CEN
tlmeter When this amount n applied 60 q
henl@hs' .hasaan subBssst is pruouvrS flrfle Or
no reaction. Tho same result follows when
flued Of this strength Is applied to q diseased
| person who is suffering from other than the
tuberculous affections, bat in persons af-
fected with tuberculosis the same quantity
produces "a strong. general and local re-
action. The general reaction consists OF an
attack OF fever which usually begins with
shiVerinE; the temperature OF the body
rises to over 80, and in some instances. even
% 4i degrees centigrade. At the same time
pains in the limbs are snoticeablc
The patient coughs, experiences much
irritableness aud nausea. In some
cases there Is noticed slight icteric
| Janadice like) coloring or exanima. re-
sembling measles, on the neck. The symp-
toms just described begin tomanifest them
selves -four or fave hours after the Injection
of the curative substance. The patient Il
much affected by the attack induced by the
fluid. aud after it Is over feels cnmparR-
lively we'll, even better, ia fact, than be-
fore the injection. The second 0r local
action produced by the injection of the
fluid Ia patient suffering from tubercn-
lusis can best be observed ia persons whose
tubcrculous affections are visible, as for i'm
stance isi tine case OF persons suffering from
lupus. The changes which ensne In these
| cases showed in surprising man
ner this specifically anti-tuhercn-
| lous effect of -rnnaedp---Y YKIthIn-
few hours after an injection sof the
| fluid has been made under the skin OF the
back. the lupus sores begin ca swell and
| redden. During the fever which the pa
tient experiences as already described, the
swelling and reddening OF the sores increase
| until finally the lupus tissue assumes In
places "A dark brown tint aud IA necrotic
| condition. After the subsidencejsof the
fever the swelling OF the lupus sores gradu-
ally decreases and possibly disappears
within two or three days. Meanwhile. how
ever. the lupus centers have become COW
cred with an incrustatioD, formed By exud-
ing serum which dries up rs II reaches the
air. These inerustations form Into scales,
which fall of after two or three weeks.
| In some Instances the effect thus de-
scFibed Il produced after a single incision
OF the curative matter. whsH a rcd smooth
| scar Is left. The changes are absolutely
limited in extent o sueAeproportions Of the
skin as are clearly re(@xnized AS lupus.
In tuberculosis Of the iymphatlc glands.
bone articulations. etc, the local reactions
are less striking. bnt are still clearly per-
ceptIble 10 tho eye and touch. la these
cases there Il swelling OF the parts affected
and more pain thansthe lupus patients suf-
fer. while Ia tho parts adjacent TO the dis
eased centers the surface sbecomcs red
/ The reaction prodnced In the internal or
l gans. especially the lungs. when the
curative substance Is injected. i not, 81
course. open TO observation apart FROM the
Increased expecEoration aud cough In ali
the experiments after the first iajeetion, all
! IL any az che tnbercnlous proccss exists ia
the body. the appearance already described
supeFvened. Absolutely NO exception was
noted whenever dose amounting 20 the
i00th part of cubic centlnleterof tbs sub
stance had been applied. 0ne may assert
| with confidence, therefore that the remedy
may bc considered as induceabie to disgno-
as, aud In doubtful eAsess hici9tent phthIsls
can positively be eslagnosled by lts uSe even II
positive information 0f the nature OF the
disease cannot be obtained by the discovery
OF baCilll. or Of elastic flbres In the sputunl.
OF by physicians examination. Tnrber-
culons Affections Of the glands latent.
tubercalous of the BONES skin tgSercnl0ms,
etc, ean by the use OF this anld be easily
and certainly diagnoxed. Moreover. Ia
tasacs of lung or Joint suhercuIosis. which
have apparently passed on, Il win be posi-
bic. BY the use of the new substance, 20 as
certain with certainty whether the morbid
procrss II really and absolutely ended.
Prof. Kocl expresses the belief that hls
remedy viii certainly prove cure for In
| ..ir.ls.r.a nllthinla MheAller hn,aea.ar tlaa