Savannah morning news. [volume] (Savannah) 1868-1887, 1886-01-04
PAsTEUR's METHOD.
How Patieats Are Treated and the Virus
Obtained
from tie Nsso York HsrGId.

that four children from Newark, bitten by
a mad dog on Dec. 9, 1885, were sent to
France to undergo NJ. Pasteur's treat
ment against rabies. Since then another
patient, named Kaufman, has arrived
from America, and he will probably not
be the last to come from that country to
seek cure from the French savant OF a
disease hitherto considered incurable.
TREATMENT or PERSONS BITTEN.
1t will be a useful thing TO show in a
| precise manner, according TO the intOrma-
| ton gained IN the laboratory of NJ. Pas
| teur, the way in which people who have
! been bitten are treated. The simplest
method will be to follow what has been
! done to the four little children. These
! children arrived in Paris Dec. Il. That
same evening they were brought to
| the laboratory in the rue d'Ulm,
and Nj. Pasteur declared him
sell ready TO inoculate them imme-
! dately, Notwithstanding that the inocula-
tions are usually performed by DR.. Gran
! cher, professor Of the Paris medical fac
ulty, at about II O'Clock on the morning of
each day. NJ. Pasteur, not having taken
his doctors degree in medicine, cannot,
| according to the French law. treat any
human malady; cannot perform any sur
gical operation on a man, and cannot le-
Bdiig even iuOtuidtt III Itibohs
THE radio BROTH
The matter used Tor incubation is COM
posed of veal broth, perfectly pure, eX-
empt from any microbe, and In which has
been dissolved little OF the marrow OF a
rabld rabbit The broth and the marrow
must be carefully prepared The broth is
made, after well known methods, with
veal which has been boiled in water. 1t
is then put in glass receivers. of a spheri-
cal form, with long necks, which are her
metically sealed by melting the necks
over a lamp. These receivers or retOrts
are then submitted for half an hour under
pressure at a heat of 115 deg. centigrade
(239 deg. Fahrenheitl in Eester some
what similar to Papin digester and those
used by Investigators in physics.
TO DESTROY ALL GERMS.
This boiling is intended to entirely de-
strov all germs the broth may contain.
To make matters more certain the retOrts
are left in a stove heated to 30 degrees
centigrade 81 degrees FahTenheit). The
germs develop if they have not been de-
stroyed and the broth becomes clouded.
When it remains clear one can decant it,
taking precautions for excessive eleanli-
ness. into other little receptacles, known
as Pasteur receptacles, or into some SINH
lar receptacle.
IMMOLATED RABBITS.
To get the marrow one must trepan two
rabbits at least each day in the labOra-
tory. To do that the animal is stretched
on dissecting board, to which it is firmly
attached by its four legs. Then il is
chloroformed. You can tell if it is thor
oughly asleep by its regular respiration,
and having lost its consciousness it can
not resist this regular breathing by any
Jerking movements. The skin OF the
upper part Of the Uranium is slit longi-
tudinally. Then, with the help of a sur
gical instrument known as the trepan,
small round piece is removed from the
skull, great care being taken not to touch
the membranes of the brain. man
must have acquired a good deal of skill
through practice to do this.
INCUBATION OF THE VICTIM.
That done, the operator inOculates with
the help of a little PraVas, or hypOdermic
syringe. under the first membrane, or
dura matter, little of the infected broth
stitches together the wound and
leaves the rabbit to recover.
On it's awakening the rabbit seems to be
as little troubled as il did before the OPP
Grafton took place. After the incubation
of very virulent broth rabies declares
itself without fail in the rabbit at the end
of six days. Two or three days later the
animal dies of complete exhaustion or
paralysis,
THE PRESERVING MARROW
Then the marrow. care having been
taken to let no foreign germ yet mixed
with it, is hung up in special TASKS per-
fectly steriliZed, and containing caustic
potash, TO thoroughly dry the air inside
of them. The TASKS are placed in room
carefully kept up at a heat of 20 deg.
centigrade COS deg. Fair. This exposure
to a dry atmosphere and constant
temperature is intended to produce
weakening of the rabic virus contained
in the marrow according TO the length
of time that the marrow remains in the
dry air. For instance, in one, two, up TO
ten or fifteen DAYS, one has what Nj. Pas
teur calls "marrow>oi one, two, ten or fif-
teen DAYS strength" and 40 on, becoming
less and less Virulent. When the opera
tor wants to use it he cuts off a little
round piece of about a centimeter in
length. which is mixed with the broth in
a quantity suitable for treating four or
five persons.
THE AMERICAN CHILDREN.
The first evening each child received
half a Pravas or hypOdermic syringe tull
of broth with marrow of IL days strength.
An adult receives each time three-quart-
ers of a syringe or a whole syringe full.
This morning after, at IL O'Clock, each
child received half a syringe OF the broth
and marrow of II days, and since the sec
Ond day they have come every morning TO
the laboratory TO receive the incubation.
Each day we take marrow which is one
day younger, and therefore one day
stronger than that used the day before.
SO the children will arrive at being
inOculated at the end Of about ten or
eleven days with marrow Of from one to
two days strength, which is certain to
give rabbit rabies by trepanning at the
end of six days. IL will do no harm to
the children, and, on the contrary, will
cure them, for the NEGOTIATIONS that have
preceded have prepared them to receive
the most virulent marrow without dan
ger.
The first marrow Of thirteen days would
not kill a rabbit. That Of six or seven
days kills them at the end Of fifteen days
and does not affect the child. The treat
ment lasts about ten days.
APAINLEss OPERATION.
The incubation causes no pain beyond
that produced by the pricking OF the very
fine needle which is inserted in the Skin
in the side, one day on the right. another
| day on the left. AZ the end OF few days
the children bear the pricking even with
out crying. There is no Inflammation OF
redness, unless IL be on the last day, after
the incubation Of the most virulent mar
| row; but there is no pain even then
During treatment the patients can go oui