San Antonio daily light. [volume] (San Antonio, Tex.) 1886-1907, 1886-03-23


mixtare was then evaporated to dryness
at low temperature and thoroughly
| exhausted with absolute alcohol both
| cold and hot, the alcoholic solution
evaporated on a water bath; but did not
| yield any slkaloid.
By most careful application of the
best processes known for the separation
of alkaloids from organic mixtures we
| have been unable to separate either
| quinine or morphine from the stomach
| Of deceased.
G. GRAHAM WATTS, NJ. d.
JAMES KENNEDY, Phi. G.
ANALYSIS OF CAPSULE.
The capsule handed to us for analysis
contained hard mass OF grayish color.
Capsule and contents weighed three
grains, contents weighed two and one
half grains, (29 graiaD the empty cap
sule weighed one half grain q grsin).
Contents were not adherent and easily
removed.
Exactly one half of the contents of the
capsule, equal to one and one-fourth
grains, Ut gTains) was reduced to pow
der and transferred to a test tube and
about two fluid drains of distilled water
added, and the mixture shaken for sew
eral minutes, when the greater portion
of the substance dissolved, leaving only
minute quantity of an insoluble sub
stance of white or grayish white color.
The mixture was allowed to stand for
some time in order that the undissolved
portion might subside, the solution which
was almost clear was decanted, and the
residue again treated with distilled
water and gently heated, but nothing
further was dissolved. Nothing was
yielded to distilled water calculated with
diluted sulphuric acid.
The aqueous solution thus obtained
was concentrated by aid OF very gentle
heat, and on treatment with reagents
gave the following reactions:
With phospho-m olybdic acid-Green-
ish yellow precipitate.
With solution iodine in potassium
iode-BrOwn precipitate.
With solution potassium iodo hydrar-
gyrate gelatinous-White precipitate.
Thus proving that the mixture under
eXaninatiOn contained an alkaloid.
Portions of the solution treated with
chlorine water and water of ammonia
cautiously added did not produce an
emerald-green color, indicating absence
Of QuiniDe.
With chlorine water and solution of
potassium-ferrocyanide did not produce
a deep-red color on addition Of water of
ammonia, indicating absence of quinine.
Absence OF fluorescence of the acidu-
sence nj oninine
nortinn Of The psprraI souoous sol,-
t;on nrodnoad With nsntrai ferrio-ohIo-
ria. u Sork.hIpo coIor inJ;ootino nra0-
ence of mornhine
Another nortio, trs.tod with conoo,-
trated nitric acid nroSnced q y,,IInw-
fsh rod coior cbanGinr
nermonenr vsIIow and NOT ranSaroJ
violet on addition Of stapnons cbioride
Indicating nresence of mornbins and ah-
sence of and distinction from hrncine
The remainder of the ooueons saIntion
soIntion on svannration yieIJed minnie
CRYSTALS sI;ghtiv coiorad which nnGer
msgnifyinG mower resemhIed mornhine
suI9befa
n q small ouoptitv of tboso orvst.Is
was sddad a Sron IF suipboomniyhSio
ooid tybicb nrodnnoS raGSiSb ngrnia
color cbanging to a beautiful sannbiro
hIne
IT, ,rotnor ANAL oror,,,r of +b, ors
tois wos oddsJ oondsntrat.d sninbnrio
acid and a nninnte fragment of hichron,~
ata not.ss;nm which nrodnceJ nnfv a
areapisb color inSicatina rrssanna ~
nnornhins oOS absanne Of nshar .It,nioid o'
re onnanns soI,t;on In nontant nth
iodic acid nrodnced a brown coIorstion
dine r. RI. iiberstion of iodine tbs
hrown color incraasina on addit;on Of
water of ammonia inSioetina Nh. nrsS
ence of mornbine and the Increase of
color nrodnced nm addition Of water of
ammonia distingnisbing mornbins frou,
other organic sSbstancss copahia Of 70
dnci.o iSdic acid
Th;s Sro.,n aolor In oo,too. Nth
starch nssts nroSUcad the bIme iodide of
starch charact.r;st;c of free iodiOe VI
m. concsntratad ,oraons soIntio, he.
came onIv siiabtIv coiorsJ on adSi+ion
of cold oncsStratsd snInbnrin odd
The anneons Solution sIiubtIv acidr.
I.ted with SiIntad bvdrocbIn,io acid
Usys white nrecini,afe On addition of
Chord. borinm soIution insoIn-
HE In excsss of bvdrochior;o cid
tbns nroving that salt in soneons
solution was a sulnhste. and ma the
above reactions have nroven the haze
was an .lLoIo;a ora hat .iLoIoiJ H,ss
morphine.
Therefore that portion of the substance
dissolved was morphine sulphate.
The residue in the tube was next
examined.
A slight excess of chemically pure
carbonate sodium was added, and small
quantity of distilled water, and the mix
ture boiled in order to deoompose the
compound and transfer the acid to a
Ink hoe h.