davidaulloa/AmericanStories huggingface dataset:
The Penn's Grove record., 1885-03-07

81 have been dreadfully tronbled with
diseases Of the kidneys and liver during
the past six months. HUNTS Kidney
and Liverl REMEDY has made me p new
man Isaac ". tairbrotaer, Providence,
The Penn's Grove record., 1885-03-07

a new name Tor tight boots-a corn
crib,
The Penn's Grove record., 1885-03-07

"HoUgh on CSrns.'
ASK for Wells Enough on Corns-0 l5c. QaleS'
complete cure, Hard or soft eornsi warts ouih"hs'
The Penn's Grove record., 1885-03-07

or frames are liable 10 become
spotted and look bad, while il Is, As a
rule, difficult to remove the spots.
Rubbing does not answer, for the stain
sticks tighter than the gliding itself,
and washing Is liable to loosen the Gilt
If put on with gum or dextrine. TIE
Paper Zsitung recommends the follow.
ing method OF ~renOyating gilt frames:
1t consists in applying with a csmel's
hair pencil a gum solution to an Oh has
been added gold bronze having the color
of the frame. Before it rs mixed with
the gum water the bronzs must be
washed with water until 1t ruas OF per
iectly clear. If application does
lot suffice 1t may be repeated until the
spots entirely disappear, but OF course
one coat must be dry before the next Is
applied. Spots treated in this way look
very we'll at FIRST, but it will not last,
for it is not able to resist the moisture
in the air unless 1t is specially prepared,
For this purpose an ordinary brisll6
brush is rubbed with a piece OF yellow
n until It is somewhat sticky, then il
is passed very lightly over the spot sew
eral times as wheE busting it. 1his
gives it a very thin Dat OF wax that
hsrdens in two or three days; in ths
meantime it must be protected agains'
dust
The Penn's Grove record., 1885-03-07

PUF five drops OF cbloroform IN g
Little cotton or wool in the bowl of a
pipe. then blow the Tapor through the
stem into an aching ear and instant re-
lief will be anorI led,
The Penn's Grove record., 1885-03-07
Farmers folly,

Travellers change their guineas, not
their characters.
The Penn's Grove record., 1885-03-07

II is said TO be mispglsion of treason
70 ask a soldier to take dinner and das
sert,
The Penn's Grove record., 1885-03-07

Quick, complete cure, all kidney. BlG-Ier and
Urinary Diseases, Sc4IdinT, Irritation, stone,
Gravel, Cstgrrh Of the Bladder, 81. Druggists,
The Penn's Grove record., 1885-03-07
The Worst UrethraI structures

Fine sense and exalted sense are not
half SO Vslaab!e as common sense.
The Penn's Grove record., 1885-03-07

II a young vomsn's disposition is
gunpowder, the sparks should be kept
svsy hon hsx.
The Penn's Grove record., 1885-03-07

Do NOT fail to SOW some oats this
month to cut green for the mixers after
the rye aud clover are used up. This
will make the pasture. go further aud
admit of more cows beng kept,
The Penn's Grove record., 1885-03-07

Palpltatlon, prapslcal swegiags, Dizziness
Indigestion, neadache, Sleeplessness, eureI Uy
Wells heaitn enewer.n
The Penn's Grove record., 1885-03-07

II is not the clock with the Ioudest
tick that goes the best.
The Penn's Grove record., 1885-03-07

L HANDSOME young lady being asked
il she ever gave a kiss, replied; "So,
but l oftsn have one stolen.
The Penn's Grove record., 1885-03-07

G,od luck must come to those who
molly earn.
The Penn's Grove record., 1885-03-07

Have you Calarrh9 Would you be wellg
Try one bottle OF Borazel.
The Penn's Grove record., 1885-03-07

The man who Is right on time never
gets left.
The Penn's Grove record., 1885-03-07

As TIE time approaches for COWS tC
come in, do not feed linseed or cotton
seed meal, nor much cora meal. Good
oats and bran, with hay, are safer, ant
some roots II O have them.
The Penn's Grove record., 1885-03-07
DIR. RAILWAYS
PILLS

For the cure OF sill disorders Of the Stomach.
Liver, Bowels, Kidneys, Blatter, Nervous DIS
cases., Loss Of Appetite, Headache, Constipation,
Costtveness, Indigestion, Dyspepsia, Bul01slesi,
Fever, Inflammation Of the Bowels, Plies, aut all
arrangements nf the Internal Vtscsra- Purely
vegetable, containing no mercury, minerals, or
deieterlOus drugs
Price, 20 cents per box. sold by ali drdGgli.A
READ FALSE AND TRUE"
send q letter stamp to RAILWAY 4 Wi., No ~
Warren street, New ForE. ES-~Inforuato1
worth thousands viii be ssut 70 you.
The Penn's Grove record., 1885-03-07

Pro manure is generally richer than
that of any other farm animal except
poultry. This is partly because the pig
is manly led on milk OF gram, aud in
part owing TO the fact that the pig will
manage TO deposit his excrement in u
place by itself. not mixed with the hitter
OF his bedding.
The Penn's Grove record., 1885-03-07

Paying the piper-settiing with the
gas-htteY.
The Penn's Grove record., 1885-03-07

Purity, sincerity. obedience and self
surrender are the marble steps that lead
TO the spiritual temple.
The Penn's Grove record., 1885-03-07

-ENVNNh eA mats
Gears ont rats, mice, rg8cnes, nies, ants, hed'
bugs, skunGs, Cnipmunks, gnphera l5c Druggists,
The Penn's Grove record., 1885-03-07

IT has been decided that q man and
under the homestead laws by getting a
divorce for the purpose. Ii this were
not The law. sham divorces might work
as much Generalization az sham mar
riages.
The Penn's Grove record., 1885-03-07

If A beautiful woman let's her heart
rest upon heI lips, the first enteIpris-
ing young man she meets raay kiss the
sweet prize away.
The Penn's Grove record., 1885-03-07

Miss AMATEUB-'I would sing some
thing more Tor you but singidg always
MAKES me tired
Ugly Old Bach-'Why don't you use
a preventative
"a preventatiyel'
Yes; stuff cotton in your ears"
The Penn's Grove record., 1885-03-07
Era1ar AHA Greasa

BARRIERS always thrive where other
The Penn's Grove record., 1885-03-07

A sHovELFUL OF manure over @ hill OF
hops will prove a great protection to the
roots, and its soluble portions will be
Incorporated with the soil so az to ben
eft the crop to the full extent next
season. The hop root is often injured
during severe Winters from deep lreez-
ing of the soil.
The Penn's Grove record., 1885-03-07

USE or SlLr.-lu mary cases OF dis.
ordered stomach, q teaspoonful of salt
IS q certain cure. In the violent inter-
uaI aching, termed cholic, add a tea
spoonful Of salt to a pint Of cold water.
drink it aud go to bed; it is one of the
speediest remedies known. The same
viii revive q person who seems almost
lead from receiving G heavy fall. etc.
in an apopiechc at, no time should be
lost 10 pouring dowe AIT water. ii suf.
Geieut sensibiiity remains 60 allow of
swallowing: If net, the head ahould be
spcuzed With cold water until the senses
return, when salt will completely re-
store the patient from his ~letharqy. IN
a hL, the feet should be placed in warm
water With mustard added, and the legs
brlskly rubbed, all bandages removed
from the neck aud a cool apartment
procured if possible. Ia many cases OF
bleeding at the lungs, when other reai-
sdies fail, DR.. Rush found two tea.
~spooufuls Of salt completely stayed the
blood. IN cases of bite from a mad
dog, wash the part with strong BRINE
for an hour, then bind on some salt
with a rag. In toothache, warm salt
and water held to the part, and renewed
two or three times will relieve in most
cases. If the gums be affected wash
tine mouth with brine. If the teeth be
covered with tartar, wash twice a day
with salt aud water. In swelled neck.
wash the part with brine, and drink it
twice a day, also, until cured. Salt viii
expel worms, If used in the food in a
moderate degree, and aids digestion,
but salt meat is injurious If used mrch.
How COLDS CAUGHT. "A large
majority OF colds in the winter time are
got by the sudden change Of tempera-
ture experienced in coming, animated
and excited, from a heated room or
crowded hall into the chill night air.
The risk will be increased if much con-
yersaticn IS INDUCED in. 1t is best,
under the circumstances, to keep the
mouth closed and breathe through the
nose. The abrupt contact with cold
drives the blood from the surface to
the Internal organs, which then suffer
from plethora and congestion. The
various troubles that follow taking cold
may be traced to failure on the part of
the skin to rid waste by insens1ble per-
SEPARATION. If food is taken while in this
congested state, much Inconvenience
and pain, with spasms or cramp, may
be experienced. The first thing TO do,
conscious of a chill, is to take q
hot air or vapor bath. and so restore
circulation and even distribution of the
blood. Always follow by a tonic ap-
plication. The proceeding may be felt
a little troublesome, but it will avert
many an attack of fever. The regular
morning bath in cold or tepId water
will aid much in reducing extreme sem
and iesseninR the %proneness
to take cold. Still, even though adopt
ing this precautionary measure, with
some tie tendency to eatarrh is consti-
.tutianal, and cannot anyhow be over
come.
The Penn's Grove record., 1885-03-07

AN English Poulbyman says that on
the first appearance of gapes, make a
quart OF oatmeal porridge, stir into it a
tallow candle, and administer 1t warm to
the chicks. Repeat the remedy every
two hours. He states that he has never
lost a chick from gapes when the above
was admInisi tered,
The Penn's Grove record., 1885-03-07

''Dm the cashiers accounts balancsg"
'No.r That odd Yes, but II
would nave been odier II it had been
even"
The Penn's Grove record., 1885-03-07
-CONsuMPrInN uuREn-

What Is the greatest curiosity IN the
world? A woman's.
The Penn's Grove record., 1885-03-07

RENovATING OLD 0BoaADs.-An old
apple orchard is a capital place Tor a
p'g-run or inclosure. especially If the
sou Is veteran and tough, Tor the pigs,
IN search Of roots Will root it up aud
convert II into 8 broken field, Tbs
mode for treating an orchard Is an
excellent way for preparing it for plow-
ing the following season, while the
manure of the pigs will add material Y
to the iruitfulness of the trees-such
manure from corn.fed porkers being
much better than that from the stables.
The Penn's Grove record., 1885-03-07
AGRTCULTURE.

DUCK RAJsINd 1t ls both economical
and sensible to raise ducks. A great
deal OF the coarse vegetable food used
in p family, With small potatoes and q
little grain, is all that will - required
to keep a small flock In thrift the year
through. DUcklugs mature early in
Their lives. one would not feel the time
passing before they are resdy for mar
ket. at five or six months old they
will, with ordinary care, dress ten or
twelve pounds per pair, and give beside
a nice lot OF feathers, which can be sold
at q fair price, or be used to increase
the family stock OF beds and pillows.
Ducks are easily kept from the she'll,
after they have passed the critical period
like chicks and poults are industrious
forsgers and thrive rapidly. Their keen
appetite, capaolous Craws and strong
digestive organs eaable them to assipll-
late any kind Of coarse or refuse food.
They are at home in the stubble field.
cleaning what the reaper left behind,
will turn into a pasture and be contegted
on grass, and they are happy in a pond,
brook or marsh, diving in the mud,
searching for animal, fish or insect food,
laryB and vegetation. They do not
require en- expensive domiclle for use.
Being generous feeders they grow right
along when once they get a start, and
their predisposltion to mature early ls
one Of the best recommendations IA
favor Of the general cultivation of ducks
for the market or table.
The Penn's Grove record., 1885-03-07

r None genuine without a punch Of green
Hops OF the wh1tsiaJeI. Shun all the vile, poison
The Penn's Grove record., 1885-03-07

Fam TFAouEE M,ssion night schooD
Nov, Johnnie, how do you spell
dumU?'
Street Urchiu-"D-i-m
Fair Ie1cheT-"What else?"
Street Urchiu-"Danno.
Fair Ieachcr-"Ob, yes, you DC,
You faTget the silent b."
Street U~rcbin-"Come, now. No
'Pnafoze,' please
The Penn's Grove record., 1885-03-07
"say, why Is everything

The best backing a young can have is
q good backbone of his own,
The Penn's Grove record., 1885-03-07
Sick Headache

For the past years 1 have been
afflicted with severe headaches and dyspeP-
sia. I was Induced to try Hoods sarsapa@
mia. and have found great relief. icheer-
fully recommend it to all'' Mrs l.. h
ASSABLE, New Haven, Conn.
Mrs. Mary C. Smith, Cambridgeport, Mass,
was a sufferer from dyspepsia and sick head
ache. She took Hoods sarsaparila ana
found it the best remedy she ever used.
Hoods ~SaTsaparilla
Sold by all druggists. 81; six for 50. MADE
only by c. !. HOOD & co, Lowell Mass
100 Doses one Dollar.
The Penn's Grove record., 1885-03-07

In Swimming the cream from milk,
there should always be milk enough
skinned with the cream to give the
butter, when churned, a bright, clean
look. Butter churned IRON clear milk
with little or no milk in 1t, will usually
have an oily or shl look. This shows
that the grain of the butter is injured,
which affects the keeping qualities OF
the butter.
The Penn's Grove record., 1885-03-07

brine HoRsEs.-horses have been
successfully cured of this vice by putting
q piece Of hard wood, an inch and a half
square, in the animals mouth, about
tue same leugth as an ordinary snafls
bit. 1t may be fastened by a thong OF
leather passed through two holes in the
ends OF the wood aud secured 10 the
birdie. It must be used in addition to
the bit, but in no way to impede the
working of the bit. Rarely adopted
tins plan with the zebra in the Zoo
which was a terrible brute at biting.
Mr.. Rarey succeeded, however, in tam
ing AID training him to harness and
drove him through the streets OF Lon
don. Animals with this vice should be
treated kindly IN the stable and not
abused with pitchfork handles, whips.
etc. An apple, crust Of bread, a piece
of beet, etc, and a kind pat, but firm,
watohfui hand and eye, with the use Of
the above wooden bit. will cure the
most inveterate bitter. The fact that ho
cannot shut his mouth or grip anything
soon dswns upon him and then he 8
G1nQueFed.
The Penn's Grove record., 1885-03-07

Fowls M MAOHISERY.-Ihe process
of fowls by machinery IN France is thus
described :-fmagine the top OF a round
tea-table divided off into sections, with
a partition between each section and a
board in front with a hslf-moon shaped
aperture in it. In each of these sections
Is an unhappy duck or chicken confined
by q chain to each leg. Through the
centre of this structure goes q round
post, and there is q series of sueh tea
table tops to the roof OF the building,
each with its divisions aud imprisoned
fowls. At stated interyel5 a man comes
round with a complicated machine filled
with q kind OF thin Cruel, and fitted
with a pipe at the end OF a long India
rubber tube. He Introduces this pipe
down the throat Of a duck, and presses
down Il pedal with his foot, and a certain
quantity of food is forced into the crea-
lures crop, a dish above showing
exactly what amount of force he is TO
use and how much food passes. This
process Is gone through with each fowl
till all are fed, and 1t Is repeated four
times q day for ducks and three for
chickens. Two weeks suffice to fatten
duck, but three are necessary for a
chicken. Apart from the necessary
confinement of the birds, the process
does not seem to be at all a cruel one,
as the amount OF food forced down their
threats ID not excessive.
The Penn's Grove record., 1885-03-07
SEVEN GREAT MONARCHIES

on the mind. His reserved knowledge IS wonderful, and sub
stimulates the main narrative in excellent annotanons and ae-
curate references to original sources of information. It is the
greatest historical work Of the time. Kansas CITY, Mo-
at abounds in ARTISTIC and de-
tails. 1t contains the studies Of a learned lifetime. and tho
faithful student viii rise from its perusal with a mind enriched
by a more vivid knowledge Of that ancient world whose
mysteries the race Of scholars has been endeavoTing to eluci.
date."-Haa. Toronto
"This is a new and marvehously cheap edition Of a standard
work. 1t i one of a series of historical works Nj Aldal Is
publishing, in which he seems to have discovered or invented
the art OF combining standard literature, good type, TASTY and
strong binding, numerous illustrations, with the lowest prices.
AE. Alden certainly leads the cheap book movement at present
We do not know of any book that can supply the place Of
Rawlinson "-Christian advocate, Buffalo, ny.
/ cQuPON Tbs Coupon wl D. received n Leu * & seats ash t55Ed al
tnS X EAErc price OF kAsLRsoEs AoSAEcHKk lSoou ssnt whn tan aJt
- u.s. = ran GATE o. 6hsp paper unsnunn mans q paperl lns eaa 4ht
Scs yc1r FRoNK rsDnas and na-zss rs paying Mvsrtaas rsesI.as
IG0-PAGE GUE sent free. The best lii
erature Of the world at the lowest prices ever known. Books
sent for EXAMINATION BEFORE PAYMENT
on reasonable evidences Of good faith. Address
JOHN q. ALDEN, Publisher,
EoR@A S22 PosnGssssA Esz Eorss
The Penn's Grove record., 1885-03-07

BY the use of Hostetters StosRa'h BltteTs the
aaggard appearance of tna cOuBenang5 and
FalUwness OF dtspeptics are sfppla1lesi by a
healthier LOOK, and as tae FOOLS sslmi ted, the
BODY acquires substance. Appetite IS restored,
and the nervous system refreshed with much
neeued slunber, through the Use bt mis- medicine,
which Is Also beneficial to pers9JS OF a rHeumstic
tendency, and an inestimable pevenaiYe OF fever
and ague.
Tor sale by all Druggists ant Dealers gen.
orally.
The Penn's Grove record., 1885-03-07

Eltters VIII keep a whole family
In robust health A year at d little cost.
To produce real genuine sleep aud
child-lIks repOse all night, axe 4 little hop
bitIer5 on retiring.
The Penn's Grove record., 1885-03-07

TnTaaA This Coupon viii b received n Leu q e cgzc sz6 -nrJ
~ ~ price OF kAELRsoEs AoNAzcaEk HSoou sss vftafn - 49,
ID @E y - from date " snsp paper uns1uon nama q u1uerl 40 80 0Gt
scnIs year ERoNE1 rsxpaas ad aaeAes ts paying Advertising =s1szS
The Tombstone., 1885-07-13
The Great English Remedy

It :. 1. never fa,liHg cure fy. nSr,ouS de- .bi. exhausted VI
 ts'iiy, Sem!ra; weak
 ness, rrerIl,uirrrhca.
 .nst UGr huCc, lnlr"-
 irnev. pGrGlys: s:s. "rd .u.l ,fe t'.r-!bla rfircts .uf ssti s!u-e, lOu.A
 tl!ies and exce>>es Tn
 H.di.re yeaG--->ur.
The Tombstone., 1885-07-13
Sainpjr Bottle Free.

C. .ned for thc S"i-n;i', sa;. SPst. :; .u:e of Chronic. Nervous aud nre-
 nisi il,ssrsEs
The Tombstone., 1885-07-13
-NOfSce.
BEN JAMES,
 Constable.

All persons knowing themselves indebted
 to ihc lA,r .iaAn PaScoc, arr requested to come forward and -et.lc ut oncc at IIir Fash ior saioor, Hr Inc sc~ounts will be placed in the hauds of !. collector.
The Tombstone., 1885-07-13
COnsta ble'S Sale.

BY VIRTUE OF AZ EXECUTION ISSUED out oi Justice G. :. cinrh's Court, Num'.rr One, Town hIp. County Cf CUrhi.c, T.r,i- tor, of Arzous. dated inc ioti; d.y of JI.nr, 1885, i'I a certain action wherein 4. !. Nit ch-il pa p'aInt f, recovered judgment against Daniel G.-t;c, De:endanI, un the IG day of June, 1885.
 lave l-v.ed upon tie following described pruu-riy. io vii: The Alkey A.iric pr hi.,- in claim. situated in Tombstone mining di.tr.ct, ,uchisc County, Arg na i'r,it"r, , ,nd abru, 5 miles ,ouih wtsierl, froru tLe cily If 1oub-t"n., 4. :. aud described ny q: post Dlaced on 5. N. center rad Uf eiaiuI, aid marked A. M. z. NJ. l. theme N. .3 de. .rec-, 9 minutes, ". 2o5feel: o.I marked A. Nj. :. Nc.S fio-. th:s It int, [ .. A. M 1 bears \. 5o de yrec-, 5 minutes. W. tS. i-et |; from post No run S. ;S6 degrees, 4 minu- tcs F.. l,2241 feel tc post marked 4. NJ C. No q thence $. 43 degrees. ;p minutes, F.. 555 feet 10 pest marked <. M. C. No. :, ibcuce $. :;6 de- srers, 4S minui.s, " .:2,i. fer; tc post Tnarkc A. N. C. No. 6. thence \. 43 degrees, 3U ra,nu- ;y-. ".%O :. ct iO platc Oi commencement. ihi- c'sisn Is honbId. d Un tIc ;. V. iy :hc 3rad-r:-~ and Washington muniUZ claInl NuI.Vc is hereby gwen that on Inc o,h .ay .,f Jttly, 1885; s. TWO o'clock. D. nI. oi that day, II, front Or inc oii.gc cf C. $ CiArs, JusIire Of ;Ec Peace, III the city of Iamt- stone. County "f CDciise, AT. l will sell all the right. title and interest of said Daniel Goettci Defendant, in ard tu .he above de- scribe property, at public auction. for cash Lawful Money, to the highest and best bid der. 10 satisfy sad execution and all costs Dated q; Tom bstOne, tae I7rll day ot June, 1885.
 BEN JAMES.
The Tombstone., 1885-07-13
Dissolution Notice

WI ,CE is hereby given that t!Ic pagtne7- rhlp h"reS"furc exIe:ing snd known ss the firn O: Jar. Finch t- Baiiwin, general me- chants ir Brnson, is this day 6issolyrd by mutual consent. Mir. Baldwin having pur- chased the interest O: C. L. Finch. All hg- h,ii,ies wHl bs paid by Dys- & BaIdsin, wbo VIII hereafter rs.tirIe the bJisinpas. All se5ts dHe tIe old firm mast or paid tn Dvsr d Baldwin, ". ". BALDWIN
 c. |. FINCH.
 PM. DyAE Bepsor Aryi, % 1898
The Tombstone., 1885-07-13
FOR S ALE l. Or Will take Stock on Shares

The undersigned nas for sale, or vi! take stock on shares, ne of the finest stock ranges in Cochise county, con- prising 9e0 acres. Good adobe hoase. large sorra. ll50 feet in diameserj well watereG, good feed; situated In Sulphur Spring Valley, l5 miles from Tombstone. For particulars ap?Iv Co
The Tombstone., 1885-07-13

 asiOss oi memory. ,sssitude. n"eiori;"i ehio sions. aversiOns to society, dininess O vls- sior., noise. Tn the head the s'ai hnid paes. Ing unnhservcd through lhe trins. ;nG man! other diseases that lead to insanity and dca'il
 Dr. Nrtie, who .s Il reguisr Sraf;Gatrt physician, will agrc. to forfeit five hundred dollars for B case of ;his kinG tEat the Vital Eestarative (under his special devise and ir-aiment) will not rUre, or for anything iIn- pure or injurious found in t. pr. N;Eue treats ali diseases succe ssfnl!y ~il:"nt Iner. cvry. Consultation free Through exam nation and aGyire, including sna!ysi> oi urine. S5 PrIce "i Vital RcstorcEiv- Sl 90 5. bottle. four times the quantity !or g.; s.n, to any address upon rcreip' "f Dgice. or -. Q. D secure from observation and in pri- Sa;e na1cc. if desired, ny A. [. MIN TIE, NJ. Dr. No l2 Kearnv street, San Francisco, Cal.
 Dr. Minii6's Kidney ReuiedN. NEPHKETI- CUM curse All kinds of kidney and bladder complaints. gCnn"rfhoea, iecuCor.i;'.-l. .,iert. For sale iy Al druggists; Si :" bottle. six bottles s.
 Dr. Mirtie's DandeIion Pills and the best d cheapest dyspepsi~ and bilious cure in .,msrk"t. For sale hy all druggists.
 Sample Bottle Free.
 '!oe sent 70 any one arolying hy letter .tatiEy syin l.ons, scE -rd Ege. Strict se- crecy in regard L, al, b',-ir-., ;-sE-Rciicns
The Tombstone., 1885-07-13

| o ]
 tor
 eby
 ice, ||vei . ow | ,e 1
 tnt', . 2 O . uir |d if | : Ils ! ice | |ltri . ne
 he
 4 S.
The Tombstone., 1885-07-13
THE EXPERT SPECIALIST.

DR. ALLEN. AS l6 WELL. KNOWN. IS h regular graduated 2hysicisn and Surgeon, educs;-d at Bowdoin College tTc Cniyer
 aiiy Of Michigan. and is acknowl"G.ed tp he ,he mos, expert surgeon in Ai- H':"iai'j o@
The Tombstone., 1885-07-13

Benson, ApsE 22, IssS.