, 1885-06-17
NEGOTIATING FOR CHOLERA.
Interesting Experiments by u Young Ply.
sIcian la spain-Favorable Results

sician la Favorable Results
London Telrgraph.l
The Madrid papers are full Of details
on the experiments Of incubation MS
a preservative against cholera, which
have been made in Valencia by a younI
Gaia an physician. DIR. Jaime ferran Is
only 33 years of age, and. after passing
through the customary curriculum at the
institutes of Tortosa and %Terragona, took
his NJ. ID. degree at Barcelona. lie has
been in practice Mt Tortosa for several
years and is already well known in this
country aud abroad for his works on
nitro telephony in 1872, and for his
curious. Investigations on micro
biology AM parasites, which wore
rewarded by the Royal A ademy Of
Me iicine in Madrid. DIR. Eerran was
sent to Toulon and Marscilles during
the last epidemic of 1885,, and he spent
several months with German, French
and Italian surgeons, studying tho
epidemic, and especially Dr. Koch's
theories on the co IN bacillus, or
cholera microbe. Those studies impelled
DIR. Ierran to pursue his investigations
on his return to his own country, and
he thus came to the conclusion that DIR.
Koch had only observed one of tn many
stages of this microbes successive
developments. senior Ferran has dis.
covered that by submitting the comma
bacillus to certain chemical elements
very similar to the bile of animals and
to the gastric Juice of the human
stomach this microbe passes through
successive and invariable stages Of
development, in one Of which he has
dAfATfA1 Nha a..- .rA..I 49,. -. Ia.
opinion, tho real generators and propa-
gators of cholera.
DR.. Ferran has made many expert
ments on men and animals, which lead
him to state that incubation by this
bacillus can produce the death of ami
mails with every symptom characteristic
of cholera. and that the incubation OF
human beings creates sympto MS identi
cal in their nature, but with less in.
tensity and no fatal results. The mos
ulation is generally practiced upon the
lower art OF both arms. In two or
three hours it produces local irritation.
difficulty in moving the limb, and dull
pain. After about four or i've
hours the pulse rises to III and even
40, and the heat of the body
to thirty-seven and forty centigrade.
The person thus inoculated feels languid,
shiyers, loses appetite, and suffers from
nausea, darrhoa, cramp and sleepless
ness. After twenty-four hours these
symptoms abate, and they generally
disappear in forty eight hours. All
successive inoculations. even to the ex-
tent of eight crbic centimeters of virus,
prove utterly harmless, both in adults
and children. In animals, after inocu
lation, it has been observed that success.
sive and larger doses of virus, intro
duced by incubation. also prove harm
less, whereas these same doses produce
death with choleraic symptoms in any
animals not previously in%oculated.
DR.. Ferran has also observed that the
local symptoms resulting from inocula
ton seldom vary, whereas the general
symptoms vary aceor ing to each case.
Not a single case has occurred in which
successive inoculations in men or ami
mails have caused death. He has trie |
his experiments on himself and other
medical men, and on hundreds of be-
levers in this p~reseryative. lie thinks
himself. therefore, justified in expecting
from these NEGOTIATIONS the same results
as have been obtained from incubation
in smallpox and carbuncle. The Madrid
academy of medicine sent down n com
mission'of medical men, and their re-
port is highly favorable to DIR. Ferran's
experiments. Foreign scientific and
medical societies and surgeons have
taken great interest in these expert
ments, and have congratulated DR.. Fer
ran.