Press and daily Dakotaian. (Yankton, Dakota Territory [S.D.]) 1880-1889, 1885-06-03
CHOLERA iNocULArI0N.

DIR. Ferran's Successful ExpcrIments
On Men and Animals-A Notable
Scientific Triumph
The young Catalan physician, DR..
Jamie Ferran, is only thirty-three years
of age. and after passing through the
customary curriculum at the institution
of Tortosa and Tarragona, took his M.
D. degree at Barcelona. He has been
in practice at Tortosa for several years,
says q correspondent of the London
Standard, and is already we'll known in
this country and abroad, for his works
on micro-telephony IN 1873, and for his
curious Investigations on icro-biology
and parasites, which were awarded by
the Royal Academy of Medicine in Mad
rid. DIR. Ferran was sent to Toulon and
Marsellles during the last epidemic of
1854, and he spent several
months with German, French and
Italian surgeons studying the epidemic,
and especially DR.. Koch's theories on
the comma bacillus, or cholera microbe,
These studies impelled DR.. Ferrsn to
pursue his Investigations on his return
to his own country, and be thus came to
the conclusion that Dr. Koch had only
observed one of tine many stages of this
microbes successive Developments,
Senior Ferran has discovered that by
submitting the comma bacillus to Ger.
tain chemical elements very similar to
the bile of animals and to the gastric
juice of the human stomach, this
microbe passes through successive and
invariable stages OF development, in
one of which he has detected the eggs,
which are, in his opinion, the real gen
orators and propagators of cholera. DR..
Ferran has made many experiments on
men and animals, which lead him to
state that incubation by this bacillus
can produce the death of animals with
every symptom of cholera, aud that the
inocculation of human beings creates
symptoms identical IN their nature, but
with less intensity and no fatal results
The inoculation Is generally practiced
upon the lower part of both arms. In
two or three hours it produces local ir
ritation, difficulty in moving the limit
and dull pain. After about four or five
hours the pulse rises to ia and even 12O
and the heat of the body to thirty .sever
and forty centigrade. The person thu
inoculated feels languid, shivers, lose
appetite and suffers from nausea, diar
rhoa, cramps and sleeplessness. Afte
twenty -four hours these symptoms abste
and they generally disappear in forty
eight hours. All successive inocula
tlons, even to the extent of eight cubi
centimeters of virus, prove utterly harm
less, both in adults and children. Ii
animals, after incubation, it has beel
observed that successive and large
doses of virus, introduced by inocula
tion, also prove harmless, whereas thes
same doses produce death with cholerai
symptoms in any animals not pre-
viously lnoculated. Dr, FerERn has ais
observed that the local symptoms result
ing from incubation seldom vary
whereas the general symptoms vary &C
cording to each case. Not single cas-
has occurred IN which successive inocr
lations IN men or ANIMALS has cause,
death. He has tried his experiments O
himself and other medical men and o
hundreds of believers in his preservativ,
He thinks himself, therefore, justified i
Expecting from these inoculations th
same results as have been obtained
small pox and carbuhole. The Madri
Academy OF Medicine sent down Q con
mission of medical men, and their repol
is highly favorable to DR.. Ferran's ez
periments. Foreign scientific and med
cal societies and surgeons have take
great interest in the experiments an
have congratulated DR.. Ferran.