The Indianapolis journal. [volume] (Indianapolis [Ind.]) 1867-1904, 1884-08-30
PAsrEUR,s SURE SUCCESS.
Putting His Hydrophobic Discoveries to the
Test-Work a Human subject

Test-Work on Human Subject.
Paris Letter in New YORK Times
M. Pasteur's thesis is that all animals vaccin-
ated by him become refractory to hydropbobia
that dog in state of undoubted hydrophobia
can bite another dog previously inoculated with
the virus of rabies and this bitten dog will not
60 mad. His theory is based upon the evolution
OF rabld microbes by series Of successive inoc-
ulatlons, commencing with the monkey and the
guinea pig (the animals most susceptible to the
diseased, passing through cats, dogs, and rabbits
pack TO the guinea pig and the monkey, the
virulence of the virus becoming attenuated with
each subject, until finally it not only becomes
lnnocuous but agent absolutely preventive
lnhis laboratory the Rue dUlm NJ Pasteur
has pursued for three years his patent search
after the mortal bacillus; around him
are Jars and bottles filed with
microbes Ri,Io hes. sufficient sufficient to dep9pulate the
below, confined in iron cages, are the wretched
beasts whose agony will add new triumph to
to the treasures Of science. There death is
everywhere. needles point dipped into one
of those pretty crystal walls would make more
ravages than the explosion of bombshell It
is the quintessence of DEATH and the thousandth
part of drop would kill more surely than the
cuTare of Ceylon or the fangs of cobra And
yet n. Pasteur will suck up through glass
tube those terrible posons to inoculate with
them dogs and cats who die from their effects
few hours afterward No doubt it is all very
cruel in the abstract, thus to torture and destroy
the poor dunno beasts but; IN this instance GER
talnly, the end Justlhes the means; haoles Is
Fanqulsheu, at least SO Tar tnitt ~ asVeur mas
succeeded in rendering animals refractory to
raoies Whatever De It's nature OF its Inode OF IN
oculaIion; ana Ihere are dogs IN that laboratory
on the LSue q YIN Whlch by LrepanaIlon ana oy
venous injection have received the virus. and yet,
after twenty different inoculations remain. at
Se emu OF tnree years perfectly neaithy. All tnls
~ asGeur set Iortn IN MS Original communlca-
tien 70 tie ana OF, every point tne com
nlassioI mas co[i ooorated ms statements. Inc
experiments maze We're numerous ana exhaust
i iS; whenever there happened to De among the
sunleGts an animal anected Win street. "a
oies, tIa1 i, Wnicn nad gone mao haIurally. ne
Was dlloWeo 70 olte Two oogs. one Nacclnaleu,
me othef nonYacclnated ana IN every instance
Mere t@entyt hree IN an .tne nrst never
eInioltea single symptom OF hydrophopla,
WINE the SECOND InVanaoiy sqccqmped-
one point Is tnen dehnlteiy estaDllshed the vac,
clliatea lnulvloual Is refractory 10 faoles, ana
ti point alone Is Of immense appearances pup
mere are TWO others SUI IN suspense, without
whIcn us pracVcaI resuits must oe nun: "
Does OF Goes not TINS lnoculatlon impair tne
neaitii OF tne patlents W Ian an unVaecinated
lholViouai VINO mas oeen oltten De cured py tle
methoaS hdlcated py u. Pasteurt Inns aIter
al, ~ Inc capltal quesIon; ~ IS not possloie 70
re-Vacelnate everybody against hydophobla,
ana, as ". Bouley observes, me discovery az
thougn sclenuncally lnterestlne Is OF no pfslctl-
cal utlllty unless AFTER the bite is received, tine
preventive action OF lnoculatlon With attenuated
virus be effcaclous to annul the action OF the
Wrns lnoculated by the olte
me commission does not consider tnat u Is
yet competent to pronounce on this question,
DnI Will commune us lapors MeanWhhe,
however tne professor IS not lole; ne argues
mat as there is no instance on record OF sponla-
neous raoles IN the human Delng, thaG ~ is al
ways the result OF an accident oy Whlch the virus
Is introduced INTO the organism, wnere " IS de7
veioped after PERIOD OF lneuoaelon varying
from twenty-five Gays 70 q tweiEemonthi tnere-
tore, IN oroer 10 put an emu 70 the communlca-
tlon OF ehe Serrloie ulsease y VII SIMPLY De nee
essary 70 make onlsaVofy the pasCorlzatloh q
an the oogs m france JUST as bne vaccination OF
every nIant is mace ooheatory, more stlii 4
am assured GnaS az tne proper inoihenb M as
teur VIII make AnoWn tne results OF an operation
perIornea one year ago on SUBJECT Oh the nu-
man species ms ~ Ing STORY
One Gay IN April, 1902 Stranger cailed upon
~ Fasteur. ny name = 4, ne sald. am
neltner z savAnt ANXIOUS 70 eAaLline INTO your
researches HOT olsciple a OF your dSetrlnes.
am tFaoesinan, ana aithough. IKE 1he majority
Oh my contemporaries an ighorahus IA seieh-
tlnc Hatters 1 am lnCereseeu IN your aisc9Fer.
les IN tne inylsiDle woriu ana 70 speak only Of
tne most recent, so soon as learaed tnat you
mad discovered the mlcrope OF RABIES:
. IhaO Is noI precisely exact rePLea me ITO
lessor; neneVe tha1 y exists, put Dy lts m
mite nttleness ~ mas SO Tar eVaoeo the lnVestl-
gatl0n OF our lnsrutnents.
i n1t oehel = quite sulneiehs pursueI Mr
-. - 49, = .- $50 $500 y
thing rs renders Is, ocular evidence comparatively
unnecessary Ihe poslton ASSIGNED py Lever
rler to Neptune was accepted as sucn py astroaT
omers long ueIore anyone hau really seen Ihab
planet 30 now. as you nave stated IN your me-
moral TO the Academy that RABIES develops
ltseH IN tne encepnalon, tnat u there accom-
plshes It's 1atal evoiuuon. enaonng you 70 pre-,
alct tne exact nlnute Wnen us Vlct1n must
oeneVe such 70 oe the acIion' as 1 oeneve also
your theory that by methodlcal cultivation OF
this invisible germ you can 50 moderate IT'S VII
ulence BY species OF accllmaton as to neu-
tralize its morolnc erect Am ! right IN the
NJ Pasteur, bowling assent, ms visitor con-
tinued: Your marvellous discovery demands its
decisive conservation you have cured rabbits,
guinea pigs, dogs ana monkeys. but yon nave
not yet exper1mented on human subject pc
cause neither you nor It will accept the response
blhty o. such an ordeal You need SUBJECT