Morning journal and courier., 1882-04-29

Total arsenic in internal organs is there fore ....-...........-...ll69 ll694 grains
 Left Arm. Jar B.
 Total weight 1230 grams equals lbs. IL 100 grams sampled tissue gave 000375 gram metal lie arsenic equals .ooo495 gram white arsenic In the entire .00609S5 gram equals .O94 grain white arsenic.
 Right Leg except thigh bone). Jar C.
 Total weight 4650 grams equals 10 lbs oz 400 gra ms sampled tissue gave .oo05 gram metallic arsenic equals .0OO66 gram white arsenic. In the entire substance ,00767 gram equals 1Is grain white arsehtc
 Thigh Bore. Jar D. Weight of cleaned bone 216 grams equals ' oz 27O.8 Entire substance failed to give any arsenic.
 Muscle from Back--Ieft Side. Jar E.
 Total weight G20 grams equals ID. oz. 200 grams sampled tissue gave .oO565 metallic arsenic equals O07458 gram white arsenic. In the entire amount of tissue .023119 gram equals .356 grain white arsenic.
 Transverse Section of Trunk at Pelvis. Jar G.
 Total weight 40tO grams equals lbs 15K 100 grams sampled tissue gave .00O225 gram metallic arsenic equals ooo297 gram white arsenic o,oo-o equals .IS6 grain white arsenic.
 Muscle from Breast-Right Side. JarH
 Total weight 510 grams equals 1 ID. 214 oz. 200 grams sampled tissue gave .0Ol9 gram metallic arsenic equals .o025 gram white arsenic.
 In the entire amount of tissue .006375 gram equals OBS grain white arsenic.
 Total weight of muscle and bony tissue analysed aud total quantity of arsenic found in them:
 Total Weight TT Arsenic Right leg (exc't thigh bne)1O lbs. oz .1ls grain Muscle ahsa DH1s from D oz sSs sF gram Muscle from breastr't sd;e l It. sG oz .oss grain
 p lb 46N 1852 grain
 24 lb 14@ oz
 Calculation ascertain the total amount of arsenic contained in the 57 lbs of body (musce' tissue and bone), weighed January 27 1882:
 57 lbs. = 912 oz.
 24 lbs 1419 = 39oN
 398 7: 912 5: .S52 X = 1.9498. The 5 lbs of body therefore contained l94sS grains
 of arsenic.
 Internal organs contained 1.1694 grains of arsenic. Total arsenic in body is therefore 3.l19S grains. Relative distribution of the arsenic in the muscle and bony tissue:
 lb sampled thigh bone contained 900 grains lb c leg contained ..............-. OH grains ib transverse section contained. .o21 grains h. :. arm contained ;..-.;:;... .o34 grains ] ID, G muscle from breast cont'd.. .087 grains ID. q muscle from back contd. .26O grains To Mr. Doolittle-There are certain data on which we can form an opinion as to how the arsenic may have been taken. My opinion is that the arsenic was taken in a very soluble and diffusble form. My reason for this is based first on the amount of arsenic in the brain. In one, third of the brain I found 25O of grain. Taking that quantity and not considering the other two thirds of the brain, the amount is exceptionally large. The quantity noticed is great deal larger in amount than in some other cases that have come under my observation. The general rule from my experience Is that arsenic taken in insoluble form is never found in the brain, either in acute or chronic cases of poison by arsenic, in other than very small traces Whereas, when arsenic is taken in the form of soluble and difusible con- pound which can pass readily into the blood, then the quantity found in the brain is gen erally very much larger, the reason being that when the arsenic is in difficult soluble form, likc white oxide, it cannot pass into the blood at any one time, to allow any great ac- emulation in the brain, since it is very readily thrown out of the body by the kid neys. That opinion in part is based on the opinion of French and German chemists and corroborated by frequent experiments of my own on animals and found in 8 few cases of arsenic poisoning that have come under my own observation.
 A recess of five minutes was here taken.
 After recess Professor Chittenden contin- ued-The second point that influences me in my opinion as to the form in which the ar- senic was taken is the large quantity found in the muscle tissue of the back, which was 1856 of a grain That quantity in the amount of tissue is exceedingly large, and in my opinion such an amount could not have been absorbed by that amount of muscle tissue except 1t had been taken in dissoluble form. The third point that influences my opinion is that when solid arsenic is taken microscopic examination usually reveals crystals of arsenic on the membrane of the alimentary canal Those are the three points on which I base my opinion as to the form in which the arsenic is taken.
 MT. Dool1ttle-Are you acquainted with Fowler's solution?
 Witness-I am it should be arsenite of potash. As ordinarily prepared one fluid ounce should contain four grains of white oxide of arsenic.
 Professor Chittenden then gave the names of Russian, Austrian and French authors to substantiate his views in regard to the form in which the arsenic was taken into the sys- tenn.
 Mir. Dooiittle-Havo you made or assisted in the chemical analysis of other bodies than this?
 Witness-Yes, I assisted in the chemical examination of the body of Mrs. Abby J. Riddle, of Norwich of all the internal organs, and later of portion of the muscle and bony tissue. I assisted also in the examina- tion of the body of Mary Stannard although did not do any of the chemical work. I am familiar, however, with the results. 1 obtained my knowledge from personal ex- hibits of the arsenic obtained The analysis was made by Professor Johnson in that case. After the 27th of January Professor John son was associated with me in the farther chemical examination of this body. He was present when I unsealed the jars containing the tissue, and saw me weigh out the DOT tions for testing. Saw me test the purity of the nitric acid. Was present and saw all of the weighings of the arsenic, and we con- suited together in regard to the methods to be employed. This refers to all of the tissue except jar A, which he did not see me weigh. In duplicate observations we never get posi- lively the same results.
 Mir. Doolittle-Was the amount of arsenic found in Jennie Cramer's body sufficient to cause death?
 Witness-The conditions vary somewhat according to the condition of the body. One author says from one to two grains may prove fatal. Dr. Taylor mentions 8 case where @ half ounce of Fowler's solution, equal to two grains, produced death in 8 young woman. Dr. Lefferty recites 8 case where two and a half grains reduced death On the other hand very much larger quanti- ties have been taken that did not produce death I will give my opinion that from two to three grains under circumstances fa- vorable to the action of the poison will pro- duce death.
 MT. Doslittle-In what form will arsenic quickest and best perform it's purpose2
 Witness-In a soluble or liquid form
 Witness continued-Vomiting often fol- lows large dose of arsenic. This may oc- cur in small doses, but is more liable to occur in large doses.
 MT. DOOllttle-t1OW soon after the pOlSon is taken does death usually occur?
 Witness-This is exceedingly variable The average time is laid down from twelve to twenty four hours There are very many cases where the fatal result has been much longer delayed, and there are cases where the result has been very much quicker. There are number of cases that occur to me where death has taken place in very short time; inside of an hour and inside of half an hour. Oxalic acid is easily traced if the examina- ton is made immediately after death. If 8 body was treated with oxalic acid after death 8 portion of it might diffuse into the flesh, although it would be very slow operation. The relative distribution of the arsenic in the muscle and bony tissue is somewhat peculiar; likewise the amount of arsenic in the throat and tongue; likewise the amount in the kid neys. From those points toxicologists are the length of time arsenic had been in the body before death, or in other words as to the time when the poison was taken prior to death In order to show the relative per centage of distribution I have drawn 8 table which appears on the bottom of page four of my pamphlet.
 At this point Judge Granger ordered a re- cess until o'clock
 Afternoon.
 DR. CHITTENDEN's oSS-ExAMINATION-A vIG-
 oROUs DISCUSSION REGARDING ARSENIC.