New-York tribune., 1875-01-27
THE PATHOLOGY OF INSANITY.

FOURTH LECTURE on INSANITY BY DR. JOHN =. GRAY
DR.. John 2. Gray yesterday delivered the
sourth OF Of lectures on insanity before the
stadens Of Bellevue Medicsli College The special sub
jset discussed wat the Pathology Of Insanity and tne
leetuter illustrated his statements with the aid OF
sge lantern, by which illuminated pictures OF sections
of ho brain IN s STAGES Of disease were thrown upon
screen. Dr. Deecke, DR.. Little and Dr. Mckay assisted
the lecturer.
Dr. Gray began hs lecture By presenting photographs
Of the medua oblongata taken At the Asylum IN Utica
and demonstrated by these the structure OF that part
He stated that the medula had boen sectopazed sue
sessay by Prof Deeeke the special pshologls OF the
Asylum in successive sections 15Ooh OF an inch In
thickness which dspaye the structure OF that nervous
center Dr. Gray then referred 10 the pathology OF In
sanity as embracing very wide range OF morbid oon'
aoDs; not only the morbid physiological disturbances
Of the brain and nervous system ooi also the
anatomical changes revealed by pOstmortem exsmiDa.
On undes general microscopic estigaOn he recalled
10 the GLASS his remarks IN the lecture on the
"Causatien OF Insanity" and said thai they would
be obliged, In examining patients supposed 30
insane take into consideration all the disordered
senditions found each individual case. In Its Wide
scope pathology OF insanity embraced also all the
asoTdered states of health acting causes or existing
ss coneomtant conditions, cerebral hemorrhsge, apo
plexy paralysis phthiss uterine diseases, etc. Upon
tbese latter the students would he instructed by their
professors; but whero they present 10 case
they formed part OF the pathological state He referred
70 the states conditions OF irritation hyper@na and
consequent anema, blood stass thrombosis emboism,
and military and disseetiDR RDeurism, as conditions
Initiating insanity Their mode Of action explained
ana al those conditions presented on screen from
srnin Wssne IN eSses ~ me Uaoa X-yiSss.
The various changes that occur In the development OF
insanity were spoken OF ss sprang1ug from simple
ogca disturbance, and through the various
StoDs OF ply biological pathology aud the anatomical
snder general heads OF nvOlutOn and tnnrati0D.
IRyOutiOn a;tlve, morbid physiological process
spder which the cells OF tue structure involved are
otamorphosed or tansfOrmed into other living cells OF
different character. The lecturer only included four
ferns OF inVolution, excluding the new formations
suoh as tumOrs, cancers These forms fatty
trvOutiOn cloudy swelling. muc0id softeninR, and the
formation Of c0llOd bodies. Under Inbtrat1On he
ton, and pgmentaiion. T1ers Is great distinction
between these TWO processes. 10 iayolunon,
sserbid process begins in the nucleus Of the
cell. the ReTminA DOl0t On the other hand, IN
n.tratiOn simply depost IN the prOtOplasm Of the
cell and does not in the beginning, involve the nucleus
In inyOuon therefore, the functional death Of the cell
k threatened from the beginning, while in IntrztiOn
there 10 simply embarrassment aud defect IL is not
wholly arrested DR.. Gray explained fully the changes
hnifested In fatty invOluon IN the destruction OF tine
Aormal cell Of the tissue affected by transformation
into tat granule cells, aud deposits Of fat which
take place 10 In6rafOn. He also spoke OF the increase
Of deposits of fat by RccreuOD. He deferred further
description OF these morbid conditions TO another ee-
tore es he desired TO exhibit them with the
In speaking OF the morbid changes in general parc the
sseturer said that many years ago, IN beginning nyest
cations into that form Of disease brain Of
deceased patient Dr. JOhu g. DaltOn-now Prof DAl-
teD-for microscopic examination without giving him
elew TO the history character OF the Tue
ported him the oew 10 points OF In es
peeiay the changes which Dr. Dalton reported ia the
spedulla.
Tue next lecture viii Dc delivered week from next
Saesday 81 lSo y. N, -