Cheraw gazette. [volume] (Cheraw, S.C.) 1835-1838, 1836-03-29


three vesicles, even though Of catarrhal ori
gin, on the lips or about the nostrils-a few
scurfy spots on any part of the body-and
even those vesicles, and the subsequent state
of the skin, that are produced by external
! injury, (asI | lately Witnessed on vaceinating
a boy whose face was injured by the explo.
sion of gun-powder, appear as capable OF
producing irreguaritv in the progress of the
vaccine veslc!e, as more extensive cuticular
affections. Vaccination, when these mala-
dies are present, seems to shew, that tho
whole surface ofthe skin is influenced at the
same time, but in separate portions; for on
one arml can often produce a perfect vac
cine pock, and on the other from the inser-
ton ola portion Of the same virus, one that
sinperfect and which would afford no se-
curity. Indeed, on the same arm within
the space ofan inch from each other, there
VIII often be this difference in the appear
ancc of the pocks-oneputting on the per-
feet character, and the others deyiating so
widely, rs to resemble more nearly that Of
an helpetic vescle,accompanied with inilam-
nation, and commonly ending in a soft,
amber coloured or blackisii 'scab-and
sometimes, cspccialyi if it be much disturbed
By scratching, in alteration. The probabll.
iiy then.is, ttu the skin, at the point ofinser-
tiu,.s sound and in its natural state in the one
| instance and diseased in the other; but not
so, rs | have observed, as to be perceptible
to the eye. ...s
. | think it proper 10 mention
that the suppurativc itch, dcrangcs the pro-
gross ofthe vaccine pussule, like the other
cutancous diseases, to which it bears re-
semblnce."
Isubjoin the Instructions for vaccine in
oculation, published by order of the medical
Council of the Royal Jcnnerian Society.
"An accurate knowledge oflhc signs Of
infection, and Of the character and progress
Of tic vac cine, vesiclc, is essential to the
success OF this inocu!ation.
"7ac signs Of infection and dsseriptiaa Of the
raccine resielc.
"Whcn vaccine inoculation proves sue.
cessful, Il smaH rcd spot, with q degree of
elevation which may be felt, commonly
commences On the third day. When ex-
amincd with magnifying glass, it seems to
consist of small tumour, surrounded by q
slight ciforcscncc.
"Bctwccn the third aild sixth day, q vesi-
Gle appears ; the shape and magnitude of
which depend much on tic mode in which
the incubation has been performed; when
it is performed,by slight pNncturc, the vcsl-
Gle viii be small and circular.
"Thc edge Of the vaccine vcs:cle is ele-
yatcd md we'll defined tho centre is de-
pressed, ard spcck is there visible, of a
darker color than the rest of the surface.
This vcsiclc is distinguished from other vesi-
c!cs by the peculiarly ofits structure, which
is cellular, and somewhat hard and firm.
At first it is Ola light pink color, sometimes
blended with a blush tint, gradually chan
cius in its progress into apearl color. Its
contents arc limpid, and almost colourless.
It COMMONLY increases in size till about the
tenth day.
"In its early stages it has usually small
infamcd ring rouad its base, which about
the ninth day begins to spread rapidly; and
about the tenth forms an arcoia, more or
less circular, an inch and a halt or moro IN
diameter. This arcola is Of n pink, scarlet,
or crimson hue; and is attended with some
degree OF hardness and tumciaction. 1t
continues nearly stationary day or two,
and then begins to fade; sometimes forming
ON its decline, two or three concentrlc circles.
"When the areola is perfectly formed, the
vesicle begins to decline frstit turns brown
ia the centre; then it is gradually converted
into a hard, smooth, shining scab, ola dark
mahogany brown color, approaching to
black and, in its general appearance, has
not unaptly been compared to the section OF
tamarind stone. This scab commonly
falls off about the end of Tic third week:
and leaves circumscribcd cicatrix, clearly
dcuotns that the true skin has been affected.
"In the computation of time, the day OF
incubation is TO be considered as the first
day.
{. Occasional deria:il,as Of TIE RACINE oesicle
from its ordinary appearances and character.
Dcviations are occasionally met with,
even in the genuine vaccine vcslclc; chiefly
with regard to its rise, duration and contents.
"It seldom or never appears earlier, but
often latcrthan the period already mentioned;
sometimes not till after the expiration OF
fortnight or three weeks but ifit then makes
regular progress, it renders the patient
equally secure as if it had appeared at the
usual time.
"Sometmcs the ves:clc is. rupturcd by
external violence. In that case, the scab
will in general be less firm, and Of a lighter
color. Occasionally also, instead OF the
regular progress to desiccation, as above
described, it passes into state otulceration,
With much more extended inflammation.