104-10428-10013 Sx greerarmemmta see ae. at ae aT en REPORT OW VISIT OF FOREIGN SCIENTISTS, OCTOBER 4, 1971 jGlh. There were four guests in the group: Dr.(Prof) Yuri I. Moskalcv; Inst. of Biophysics, Ministry. of Public Health, Moscow, 004547 Dr. Alexei A, Moiseev; Central Inst. for Advanced Medical Studies, Moscow , Dr. Jean-Claude Nenot; CEA, Centre D'Etudes Nuclaires, Fontenay-aux~ Roses, France. Dr. R. Masse,; CEA as above, The four yi hie Really ipaveling topether, but by coincidence were articipants ; gane iransuranium biology Symposium at Han ord during e week o reer They Were in oan Francisco by cha e same me and desired to visit Berkeley on the same day Mrs. Ann@ Low-Beer picked up the four guests in Sm Francisco and brought them to the Donner Laboratory where they were greeted by Dr. John Lawrence, Drs. Donald Van Dyke, James MaRae, and Howard Parker took them on a short tour of the Anger camera facility and whole-body counting and scanning equipment. The current uses and potential in medical diagnosis were dis- cussed. Major questions concerned the use of these instruments in monit- oring and assessing the extent of persons contaminated with radionuclides in industrial accidents, Lunch was attended by Dr. Hardin Jones, the four guests, Drs. Van Dyke and Parker, and Dr. Patricia Durbin, who acted as hostess and guide thrcugh the day. Topics discussed at lunch were centered about the Transuranium symposium. The efficacy of two new techniques to remove lung contamina- tion by alpha~emitting isotopes yas considered. The two techniques are lung Lavage and aerosolized ch ing agents, particularly DTPA, A tour of Bldg. 7h followéd° lunch. Three of the visitors are biologists~~ _Drs. Moskalev and Nénot are physicians... and Dr. Masse is a veterinarian -- ith animal experiments or the interpretation of the results of animal experiments. They were much interested in how one achieved and managed a "biologically clean" rodent colony, in the minimum mainte- nance rabbit rooma, and the cage-washing facilities. There was some discussion about the 90-Sr-injected monkeys, ther exposure levels, years of follow-up, and the essential absence of biological effects at the dose levels in the study. @ A two-hour general discussion between and among the four guests and Dr. Durbin followed the building tour. The chief topics discussed were how to explain the observed differences in the metabolism of the transuranic elements among species. The usefulness and verifiability of models of human Pu metabblism were considered at great length. New areas of re-~ search in internal emitters problems were considered including the influ- ence of age on local dose and ultimate biological end-points; the useful- ness of common experiments with various species particularly those with known Variations in iron metabolism, bone formation rates and liver func- tion.
13-00000 Dr. Durbin proposed a collaborative effort with two of Dr. Moskalev's colleagues. They have collected data on human skeleton weights, but now do not have the time or interest to write up their material. Dr. Durbin has collected all of the 19th century and early 20th century human bone weight data and would like to add the modern Russian material ‘to the set.  Dr..Moskalev agreed to propose a joint article with his colleagues Looking towards” publication in an international journal. He sus ‘ested that the original data would be forwarded in any case as soon as it cculd be copied. In the late afternoon the visitors toured (briefly) the Bevatron guided by Ralph Thomas; the californium separation facility guided by Francis McCarty; and the Hi-~lac guided by Al Ghiorso. Dr. Moiseev, who is a physicist, was very much intrigued by the proposal to make an advanced scientific instrument by joining the Bevatron and the Hi-lac._ Dr lev was not interested in how the machines worked, "physics was not. his “fieldthe said, but asked what he as a biclogist might do in the nature of radiobiology experiments with such machines. wr. Mioskalev repretted that it had not been possible to visit with Dr. “Tobias. (We could probably have fit in a few minutes or made arrange- ments for the following day, but I had run them ragged with sight-seeing the day before, Monday was very full, and frankly they were exhausted and needed rest. pwd). They would also have liked to visit the Medical Services group. Mrs. Low-Beer tried to fi11 them in on the duties and routine of that group. Comments on money, budgets, problems of communication, demands on time such as committees, etc. ran thpough all of the conversations. Dr. Nenot and Dr. Moiseev spoke English and understood it well. Dr. Mokkalev and | Dr. Masse understood more English than they could speak. All four are \ chiefly odGiipied with radiation protection and especially with problems raised by internal emitters. Dr. Moskalev is his country's representa- -tive on the ICRP internal dose committee. They all forsee the develop=_ tment of nuclear power in their countries at a fast pace, This obviously bincludes, as they were cereful to point out, Pu fast breeders, hence ‘the overriding interest in Pu and its transplutonium contaérinants. The Russian visitors will te puests of the AEC Division of Piclogy and Medicine in Washington. (I feel certain we will roceive good marks as hosts and as sclontists. pwd). One further pgint needs to be added. Although nuclear medicine is not a cuurent specialty in either country, and the use of nuclear medical techniques, especially as diagnostic tools, is very limited, the two physicians indicated thay they personally were much interested, and there was a definite trend in both countries towards more and more use of such tools, "It is coming", they said. pal