‘‘(3) to identify, coordinate, and support re-
search, research training, and related activities (in-
cluding the development of new and the refinement 
of existing treatments) with respect to both primary 
and secondary pain, including— 
‘‘(A) acute pain; 
‘‘(B) cancer and HIV-related pain, particu-
larly at the end of life; 
‘‘(C) back pain, headache pain, and other 
chronic and intractable pain; and 
‘‘(D) other painful conditions; 
‘‘(4) to identify, coordinate, and support re-
search, research training, and related activities with 
respect to palliative care; 
‘‘(5) to conduct and support pain and palliative 
care research, research training, and related activi-
ties that have been identified as requiring additional, 
special priority as determined appropriate by the Di-
rector of the Center and the Advisory Board estab-
lished under subsection (e); 
‘‘(6) to coordinate all pain and palliative care 
research, research training, and related activities 
being carried out among the national research insti-
tutes or in any such institute;
‘‘(7) to ensure the prompt and effective dis-
semination of current and future research results to 
improve patient access to and provider delivery of 
pain and palliative care; 
‘‘(8) to initiate a comprehensive program of col-
laborative interdisciplinary research among schools, 
colleges, and universities, including schools of medi-
cine and osteopathy, schools of pharmacy and phar-
macology, schools of nursing, schools of dentistry, 
schools of physical therapy, schools of occupational 
therapy, and schools of clinical psychology, com-
prehensive health care centers and systems, and spe-
cialized centers of pain research or treatment; and 
‘‘(9) to report not less than annually on the 
state of public and private funding for pain and pal-
liative care research and the adequacy of such fund-
ing, taking into account the specific categories de-
scribed in paragraphs (3) and (4). 
‘‘(e) ADVISORY COUNCIL.— 
‘‘(1) IN GENERAL.—The Center shall have an 
advisory council to be known as the National Pain 
and Palliative Care Research Center Advisory Board 
(in this section referred to as the ‘Advisory Board’).
‘‘(2) MEMBERSHIP.—The Advisory Board shall 
be established and maintained in accordance with 
section 406, except that— 
‘‘(A) the appointed voting members shall 
include— 
‘‘(i) representatives of the broad range 
of medical, health, and scientific disciplines 
involved in research and treatment related 
to the categories of pain and palliative care 
described in paragraphs (3) and (4) of 
subsection (d), including individuals with 
expertise and training in pain medicine, 
clinical psychology, physical medicine, and 
rehabilitative services (including physical 
therapy and occupational therapy), phar-
macy and pharmacology, nursing, and den-
tistry; and 
‘‘(ii) representatives of painful pa-
tients; and 
‘‘(B) the nonvoting ex officio members 
shall include— 
‘‘(i) the Director of the National Can-
cer Institute;
‘‘(ii) the Director of the National In-
stitute of Dental and Craniofacial Re-
search; 
‘‘(iii) the Director of the National In-
stitute of Child Health and Human Devel-
opment; 
‘‘(iv) the Director of the National In-
stitute of Nursing Research; 
‘‘(v) the Director of the National In-
stitute of Allergy and Infectious Diseases; 
‘‘(vi) the Director of the National In-
stitute of Arthritis and Musculoskeletal 
and Skin Diseases; 
‘‘(vii) the Director of the National In-
stitute of Mental Health; 
‘‘(viii) the Director of the National In-
stitute of Neurological Disorders and 
Stroke; 
‘‘(ix) the Director of the National In-
stitute on Drug Abuse; 
‘‘(x) the Director of the National In-
stitute on Disability and Rehabilitation Re-
search;
‘‘(xi) the Director of the National In-
stitute of Biomedical Imaging and Bio-
engineering; and 
‘‘(xii) the Director of the National 
Bioethics Advisory Commission. 
‘‘(3) DUTIES.—The Advisory Board shall ad-
vise, assist, consult with, and make recommenda-
tions to the Director of the Center regarding the 
matters set forth in subsection (d), including coordi-
nation, research, funding, and purposes. 
‘‘(f) ESTABLISHMENT OF REGIONAL PAIN RESEARCH 
CENTERS.— 
‘‘(1) ESTABLISHMENT.—To facilitate and en-
hance the research, research training, and related 
activities to be carried out by the Center, the Direc-
tor of NIH, in consultation with the Director of the 
Center and the Advisory Board, shall establish not 
less than 6 regional pain research centers, which 
shall operate as part of the Center. 
‘‘(2) FOCUS AND DISTRIBUTION.— 
‘‘(A) FOCUS.—Not less than 4 of the re-
gional centers established under paragraph (1) 
shall have as their primary focus 1 of the cat-
egories of pain described in subparagraphs (A), 
(B), and (C) of subsection (d)(3).
‘‘(B) DISTRIBUTION.—One regional pain 
research center shall be established in each of 
the following regions of the United States (as 
such regions are determined by the Director of 
the Center): 
‘‘(i) The Northeast region. 
‘‘(ii) The Southeast region. 
‘‘(iii) The Midwest region. 
‘‘(iv) The Southwest region. 
‘‘(v) The West region, including Ha-
waii. 
‘‘(vi) The Pacific Northwest region, 
including Alaska. 
‘‘(3) SELECTION.—The regional centers shall be 
selected through a competitive process from among 
institutions and centers of the type described in sub-
section (d)(8). 
‘‘(g) ANNUAL CONSENSUS CONFERENCE ON PAIN 
AND PALLIATIVE CARE RESEARCH.—To assist the Center 
in the establishment and maintenance of a national agen-
da for pain and palliative care research, and to ensure that 
the Center remains abreast of research and clinical devel-
opments in both the public and private sectors, the Direc-
tor of the Center shall convene each year a consensus con-