IB 
Union Calendar No. 153 
117TH CONGRESS 
1ST SESSION H. R. 1193 
[Report No. 117–212] 
To amend title IV of the Public Health Service Act to direct the Director 
of the National Institutes of Health, in consultation with the Director 
of the National Heart, Lung, and Blood Institute, shall establish a 
program under which the Director of the National Institutes of Health 
shall support or conduct research on valvular heart disease, and for 
other purposes. 
IN THE HOUSE OF REPRESENTATIVES 
FEBRUARY 22, 2021 
Mr. BARR introduced the following bill; which was referred to the Committee 
on Energy and Commerce 
DECEMBER 8, 2021 
Additional sponsors: Miss RICE of New York, Mr. FITZPATRICK, Mr. GUTH-
RIE, Mr. KILMER, Mr. RODNEY DAVIS of Illinois, Mr. SMITH of New Jer-
sey, Mr. TIMMONS, Mrs. WAGNER, Mr. HUIZENGA, Mr. ARRINGTON, Mr. 
MCHENRY, Mr. TAYLOR, Mr. ROGERS of Kentucky, Mr. COMER, Mr. 
GOODEN of Texas, Mr. DAVIDSON, Mr. RUTHERFORD, Mr. SMUCKER, 
Mr. JOYCE
of Pennsylvania, Mr. MEEKS, Mr. FERGUSON, Mr. 
KRISHNAMOORTHI, Mr. REED, Mr. BOST, Mr. NEWHOUSE, Mr. PALAZZO, 
Mr. AUSTIN SCOTT of Georgia, Mr. DIAZ-BALART, Mr. MURPHY of North 
Carolina, Mr. JOYCE
of Ohio, Mr. YARMUTH, Ms. TENNEY, Mr. 
LOUDERMILK, Mr. STAUBER, Mr. TONKO, Mr. WELCH, Mr. FORTEN-
BERRY, Mr. STIVERS, Mr. BUCSHON, Mr. VALADAO, Mr. PETERS, Mr. 
ROSE, Mr. GONZALEZ of Ohio, Mr. LONG, Mr. CARTER of Georgia, Mr. 
VAN DREW, Mr. KINZINGER, Mr. NORMAN, Mr. WENSTRUP, Mr. JACK-
SON, Mr. YOUNG, Mr. PERLMUTTER, Ms. DEAN, Mr. MEUSER, Mr. 
SUOZZI, Mr. MCCAUL, Mr. PENCE, Mr. WITTMAN, Mrs. CAROLYN B. 
MALONEY of New York, Mr. WOMACK, Mr. LUETKEMEYER, Mr. SIMP-
SON, Ms. STEFANIK, Mr. HILL, Mr. KILDEE, Mr. DUNCAN, Mr. DUNN, 
Mrs. BEATTY, Ms. DEGETTE, Mr. VARGAS, Mr. GOTTHEIMER, Mr. 
MCKINLEY, Mr. FLEISCHMANN, Mr. ZELDIN, Mr. MORELLE, Mr. 
BUTTERFIELD, Mr. GALLAGHER, Mr. BISHOP
of Georgia, Ms. 
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BARRAGA´N, Ms. KUSTER, Mr. PANETTA, Mrs. MILLER of West Virginia, 
Mr. GARBARINO, Mr. MOONEY, Mr. BACON, Mr. SMITH of Missouri, Mrs. 
TORRES of California, Mr. CALVERT, Mr. ADERHOLT, Mr. LATURNER, 
Mr. LAHOOD, Mr. POSEY, Mr. BABIN, Mr. HOLLINGSWORTH, Ms. 
WATERS, Mr. LAMALFA, Mr. STEIL, Ms. GARCIA of Texas, Mr. GREEN 
of Texas, Mrs. LESKO, Mr. CICILLINE, Ms. JACKSON LEE, Ms. HERRERA 
BEUTLER, Mr. BERA, Mr. BANKS, Mr. TRONE, Mrs. MCBATH, Mrs. 
LURIA, Mr. HIGGINS of Louisiana, Mr. WILLIAMS of Texas, Mr. LUCAS, 
Mr. KUSTOFF, Mr. RICE of South Carolina, Mr. MAST, Mr. BRENDAN 
F. BOYLE of Pennsylvania, Mr. MEIJER, Mrs. MURPHY of Florida, Mr. 
MOORE of Utah, Mr. CARTWRIGHT, Mr. KIM of New Jersey, Mr. 
QUIGLEY, Ms. STEVENS, Mr. DAVID SCOTT of Georgia, Ms. BLUNT 
ROCHESTER, Mr. BALDERSON, Mr. NORCROSS, Mr. LAMBORN, Mr. BILI-
RAKIS, Mr. COLE, Mrs. BICE of Oklahoma, Mr. CURTIS, Ms. ROSS, Mr. 
ARMSTRONG, Mr. SESSIONS, Mr. HARDER of California, Mr. DELGADO, 
Mr. GRAVES of Missouri, Mr. VELA, Mrs. KIM of California, Mr. HUD-
SON, Ms. CRAIG, Ms. SCHRIER, Mr. MANN, Mr. EMMER, Mr. JOHNSON 
of Ohio, Mrs. HINSON, Mr. ALLEN, Ms. SALAZAR, Mr. C. SCOTT FRANK-
LIN of Florida, Mr. KHANNA, Mrs. MILLER-MEEKS, Mr. JOHNSON of 
Louisiana, Mr. CLEAVER, Ms. WILLIAMS of Georgia, Ms. MATSUI, Mr. 
PAPPAS, Mr. MICHAEL F. DOYLE of Pennsylvania, Mr. RUIZ, Mr. 
STEUBE, Mrs. WALORSKI, Mr. SCHNEIDER, Mr. O’HALLERAN, Mr. 
MULLIN, Mr. LIEU, Mr. LAMB, Mr. BURGESS, Mr. AUCHINCLOSS, Mr. 
AMODEI, Ms. STANSBURY, Mr. LYNCH, Ms. CHENEY, Ms. ROYBAL- 
ALLARD, Mrs. FLETCHER, Mrs. LEE of Nevada, Ms. MALLIOTAKIS, Mr. 
SOTO, Mr. GUEST, Mr. RUSH, Mr. WALBERG, Ms. LETLOW, Ms. 
WEXTON, Mr. CROW, and Mr. CASTEN 
DECEMBER 8, 2021 
Reported with amendments, committed to the Committee of the Whole House 
on the State of the Union, and ordered to be printed 
[Strike out all after the enacting clause and insert the part printed in italic] 
[For text of introduced bill, see copy of bill as introduced on February 22, 2021] 
A BILL 
To amend title IV of the Public Health Service Act to 
direct the Director of the National Institutes of Health, 
in consultation with the Director of the National Heart, 
Lung, and Blood Institute, shall establish a program 
under which the Director of the National Institutes of 
Health shall support or conduct research on valvular 
heart disease, and for other purposes. 
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Be it enacted by the Senate and House of Representa-
tives of the United States of America in Congress assembled, 
SECTION 1. SHORT TITLE. 
This Act may be cited as the ‘‘Cardiovascular Ad-
vances in Research and Opportunities Legacy Act’’. 
SEC. 2. GRANTS FOR VALVULAR HEART DISEASE RE-
SEARCH. 
Subpart 2 of part C of title IV of the Public Health 
Service Act (42 U.S.C. 285b et seq.) is amended by inserting 
after section 424C (42 U.S.C. 285b–7c) the following: 
‘‘SEC. 424D. GRANTS FOR VALVULAR HEART DISEASE RE-
SEARCH. 
‘‘(a) IN GENERAL.—The Director of the National In-
stitutes of Health, in consultation with the Director of the 
Institute, shall support or conduct research regarding val-
vular heart disease. 
‘‘(b) SUPPORT
GUIDELINES.—The distribution of 
funding authorized under subsection (a) may be used to 
pursue the following outcomes: 
‘‘(1) Using precision medicine and advanced 
technological imaging to generate data on individuals 
with valvular heart disease. 
‘‘(2) Identifying and developing a cohort of indi-
viduals with valvular heart disease and available 
data. 
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‘‘(3) Corroborating data generated through clin-
ical trials to develop a prediction model to distin-
guish individuals at high risk for sudden cardiac ar-
rest or sudden cardiac death from valvular heart dis-
ease. 
‘‘(4) For other outcomes needed to acquire nec-
essary data on valvular heart disease. 
‘‘(c) MITRAL VALVE PROLAPSE WORKSHOP.—Not later 
than one year after the date of the enactment of this section, 
the Director of the Institute shall convene a workshop com-
posed of subject matter experts and stakeholders to identify 
research needs and opportunities to develop prescriptive 
guidelines for treatment of individuals with mitral valve 
prolapse. 
‘‘(d) AUTHORIZATION OF APPROPRIATIONS.—For the 
purpose of carrying out this section, there is authorized to 
be appropriated $20,000,000 for each of fiscal years 2022 
through 2026.’’. 
SEC. 3. PROGRAMS OF CENTERS FOR DISEASE CONTROL 
AND PREVENTION. 
Part B of title III of the Public Health Service Act 
(42 U.S.C. 243 et seq.) is amended by inserting after section 
312 the following section: 
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‘‘SEC. 312A. PREVENTION OF SUDDEN CARDIAC DEATH AS A 
RESULT OF VALVULAR HEART DISEASE. 
‘‘(a) IN GENERAL.—The Secretary, acting through the 
Director of the Centers for Disease Control and Prevention, 
may carry out projects to increase education, awareness, 
or diagnosis of valvular heart disease and to reduce the inci-
dence of sudden cardiac death caused by valvular heart dis-
ease. Such projects may be carried out by the Secretary di-
rectly or through awards of grants or contracts to public 
or nonprofit private entities. The Secretary may directly 
(or through such awards) provide technical assistance with 
respect to the planning, development, and operation of such 
projects. 
‘‘(b) CERTAIN ACTIVITIES.—Upon availability of ap-
plicable data, projects carried out under subsection (a) may 
include— 
‘‘(1) continuing the activities at the Division for 
Heart Disease and Stroke Prevention, including those 
related to valvular heart disease; 
‘‘(2) broadening the awareness of the public con-
cerning the risk factors for, the symptoms of, and the 
public health consequences of valvular heart disease; 
and 
‘‘(3) enhancing surveillance of out-of-hospital 
cardiac arrests to improve patient outcomes. 
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‘‘(c) GRANT PRIORITIZATION.—The Secretary may, in 
awarding grants or entering into contracts pursuant to sub-
section (a), give priority to entities seeking to carry out 
projects that target populations most impacted by valvular 
heart disease. 
‘‘(d) COORDINATION OF ACTIVITIES.—The Secretary 
shall ensure that activities under this section are coordi-
nated, as appropriate, with other agencies of the Public 
Health Service that carry out activities regarding valvular 
heart disease. 
‘‘(e) BEST PRACTICES.—The Secretary, acting through 
the Director of the Centers for Disease Control and Preven-
tion, shall— 
‘‘(1) collect and analyze the findings of research 
conducted with respect to valvular heart disease; and 
‘‘(2) taking into account such findings, publish 
on the website of the Centers for Disease Control and 
Prevention best practices for physicians and other 
health care providers who provide care to individuals 
with valvular heart disease.’’. 
Amend the title so as to read: ‘‘A bill to amend title 
IV of the Public Health Service Act to direct the Director 
of the National Institutes of Health, in consultation with 
the Director of the National Heart, Lung, and Blood In-
stitute, to establish a program under which the Director 
of the National Institutes of Health shall support or con-
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duct research on valvular heart disease, and for other 
purposes.’’. 
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