IIB 
111TH CONGRESS 
2D SESSION 
H. R. 1230 
IN THE SENATE OF THE UNITED STATES 
NOVEMBER 15, 2010 
Received; read twice and referred to the Committee on Health, Education, 
Labor, and Pensions 
AN ACT 
To amend the Public Health Service Act to provide for 
research on acquired bone marrow failure diseases, mi-
nority-focused programs on such diseases, and the devel-
opment of best practices for diagnosis of and care for 
individuals with such diseases. 
Be it enacted by the Senate and House of Representa-
tives of the United States of America in Congress assembled, 
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SECTION 1. SHORT TITLE. 
This Act may be cited as the ‘‘Acquired Bone Marrow 
Failure Disease Research and Treatment Act of 2010’’. 
SEC. 2. ACQUIRED BONE MARROW FAILURE DISEASE RE-
SEARCH. 
Part B of title III of the Public Health Service Act 
(42 U.S.C. 243 et seq.) is amended by inserting after sec-
tion 317T the following: 
‘‘SEC. 317U. ACQUIRED BONE MARROW FAILURE DISEASE 
RESEARCH. 
‘‘(a) IN GENERAL.—The Secretary may conduct re-
search on acquired bone marrow failure diseases. Such re-
search may address factors including— 
‘‘(1) trends in the characteristics of individuals 
who are diagnosed with acquired bone marrow fail-
ure diseases, including age, race and ethnicity, gen-
eral geographic location, sex, family history, and any 
other characteristics determined appropriate by the 
Secretary; 
‘‘(2) the genetic and environmental factors, in-
cluding exposure to toxins, that may be associated 
with developing acquired bone marrow failure dis-
eases; 
‘‘(3) approaches to treating acquired bone mar-
row failure diseases; 
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‘‘(4) outcomes for individuals treated for ac-
quired bone marrow failure diseases, including out-
comes for recipients of stem cell therapeutic prod-
ucts; and 
‘‘(5) any other factors pertaining to acquired 
bone marrow failure diseases determined appropriate 
by the Secretary. 
‘‘(b) COLLABORATION WITH THE RADIATION INJURY 
TREATMENT NETWORK.—In carrying out subsection (a), 
the Secretary may collaborate with the Radiation Injury 
Treatment Network of the C.W. Bill Young Cell Trans-
plantation Program established pursuant to section 379 
to— 
‘‘(1) augment data for the studies under such 
subsection; 
‘‘(2) access technical assistance that may be 
provided by the Radiation Injury Treatment Net-
work; or 
‘‘(3) perform joint research projects. 
‘‘(c) DEFINITION.—In this section, the term ‘ac-
quired bone marrow failure disease’ means— 
‘‘(1) myelodysplastic syndromes (MDS); 
‘‘(2) aplastic anemia; 
‘‘(3) 
paroxysmal 
nocturnal 
hemoglobinuria 
(PNH); 
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‘‘(4) pure red cell aplasia; 
‘‘(5) acute myeloid leukemia that has pro-
gressed from myelodysplastic syndromes; 
‘‘(6) large granular lymphocytic leukemia; or 
‘‘(7) any other bone marrow failure disease 
specified by the Secretary, to the extent such disease 
is acquired and not inherited, as determined by the 
Secretary.’’. 
SEC. 3. MINORITY-FOCUSED PROGRAMS ON ACQUIRED 
BONE MARROW FAILURE DISEASES. 
Title XVII of the Public Health Service Act (42 
U.S.C. 300u et seq.) is amended by inserting after section 
1707A the following: 
‘‘SEC. 
1707B. 
MINORITY-FOCUSED 
PROGRAMS 
ON 
AC-
QUIRED BONE MARROW FAILURE DISEASES. 
‘‘(a) INFORMATION AND REFERRAL SERVICES.— 
‘‘(1) IN GENERAL.—The Secretary may estab-
lish and coordinate outreach and informational pro-
grams targeted to minority populations, including 
Hispanic, Asian-American, Native Hawaiian, and 
Pacific Islander populations, that are affected by ac-
quired bone marrow failure diseases. 
‘‘(2) PROGRAM
ACTIVITIES.—Programs under 
subsection (a) may carry out activities that in-
clude— 
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‘‘(A) making information about treatment 
options and clinical trials for acquired bone 
marrow failure diseases publicly available; and 
‘‘(B) providing referral services for treat-
ment options and clinical trials. 
‘‘(b) DEFINITION.—In this section, the term ‘ac-
quired bone marrow failure disease’ has the meaning given 
such term in section 317U(c).’’. 
SEC. 4. BEST PRACTICES FOR DIAGNOSIS OF AND CARE 
FOR INDIVIDUALS WITH ACQUIRED BONE 
MARROW FAILURE DISEASES. 
Part B of title III of the Public Health Service Act 
(42 U.S.C. 243 et seq.), as amended by section 2, is fur-
ther amended by inserting after section 317U the fol-
lowing: 
‘‘SEC. 317V. BEST PRACTICES FOR DIAGNOSIS OF AND CARE 
FOR INDIVIDUALS WITH ACQUIRED BONE 
MARROW FAILURE DISEASES. 
‘‘(a) GRANTS.—The Secretary, acting through the 
Director of the Agency for Healthcare Research and Qual-
ity, may award grants to researchers to study best prac-
tices with respect to diagnosing acquired bone marrow 
failure diseases and providing care to individuals with such 
diseases. 
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