IV 
118TH CONGRESS 
2D SESSION 
H. RES. 1124 
Expressing support for the designation of the last Tuesday of April each 
year as ‘‘APOL1-Mediated Kidney Disease (AMKD) Awareness Day’’. 
IN THE HOUSE OF REPRESENTATIVES 
APRIL 9, 2024 
Ms. PLASKETT (for herself, Ms. SEWELL, Ms. ADAMS, Ms. DELBENE, Mrs. 
CHERFILUS-MCCORMICK, Ms. CLARKE of New York, Ms. WILD, and Mr. 
DAVIS of Illinois) submitted the following resolution; which was referred 
to the Committee on Energy and Commerce 
RESOLUTION 
Expressing support for the designation of the last Tuesday 
of April each year as ‘‘APOL1-Mediated Kidney Disease 
(AMKD) Awareness Day’’. 
Whereas kidney disease affects an estimated 37,000,000 
Americans, and more than 550,000 are on dialysis; 
Whereas Black individuals with kidney disease are more likely 
to develop kidney failure than any other racial group; 
Whereas the health disparities in kidney failure are 
unsustainable, with Black people making up 13 percent 
of the United States population but accounting for 35 
percent of those with kidney failure; 
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•HRES 1124 IH 
Whereas kidney failure places enormous physical, emotional, 
and financial burdens on individuals and costs the Medi-
care Program over $50,000,000,000 annually; 
Whereas there are genetic factors that can increase an indi-
vidual’s risk for kidney disease; 
Whereas one such genetic factor is having variants 
(mutations) in the apolipoprotein L1 (APOL1) gene; 
Whereas people are more likely to have APOL1 gene variants 
if they are from Western or Central Africa or have an 
ancestor who came from these regions; 
Whereas these variants can increase susceptibility for 
APOL1-mediated kidney disease (AMKD), a rapidly pro-
gressive form of kidney disease that can lead to kidney 
failure; 
Whereas it is estimated that if a patient has variants in both 
copies of the APOL1 gene, there is a 1 in 5 chance they 
will go on to develop kidney disease, and an estimated 13 
percent of Black Americans have variants in both copies 
of the APOL1 gene; 
Whereas a person with AMKD may not have any symptoms 
of kidney disease until their kidneys are close to failing; 
Whereas genetic testing can reveal an individual’s risk for 
AMKD, empowering them to take the steps necessary to 
protect their kidney health before it is too late; 
Whereas individuals who are found to have APOL1 genetic 
variants can reduce their risk for kidney failure by meet-
ing with their doctor regularly, eating a healthy diet, tak-
ing all medications as prescribed, exercising for at least 
30 minutes a day, and not smoking or using tobacco; 
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•HRES 1124 IH 
Whereas additional awareness and research of APOL1 ge-
netic mutations are needed to improve understanding of 
the kidney disease disparities in this population; 
Whereas there are currently no Food and Drug Administra-
tion-approved treatments available for APOL1-mediated 
kidney disease, but ongoing research and clinical trials 
could provide an opportunity for researchers to develop 
and test safe treatments for APOL1-mediated kidney dis-
ease; and 
Whereas the House of Representatives can raise public 
awareness of APOL1-mediated kidney disease: Now, 
therefore, be it 
Resolved, That the House of Representatives— 
(1) expresses support for the designation of 
‘‘APOL1-Mediated Kidney Disease (AMKD) Aware-
ness Day’’; 
(2) encourages each person of the United 
States to become better informed about and aware 
of kidney disease and APOL1-mediated kidney dis-
ease; and 
(3) encourages people from or with ancestry 
from Western and Central Africa to consider genetic 
testing for APOL1 gene mutations. 
Æ 
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