I 
115TH CONGRESS 
1ST SESSION H. R. 4501 
To increase funding for the State response to the opioid misuse crisis and 
to provide funding for research on addiction and pain related to the 
substance misuse crisis. 
IN THE HOUSE OF REPRESENTATIVES 
NOVEMBER 30, 2017 
Mr. LOEBSACK (for himself, Ms. SHEA-PORTER, Mrs. NAPOLITANO, and Ms. 
KUSTER of New Hampshire) introduced the following bill; which was re-
ferred to the Committee on Energy and Commerce 
A BILL 
To increase funding for the State response to the opioid 
misuse crisis and to provide funding for research on 
addiction and pain related to the substance misuse crisis. 
Be it enacted by the Senate and House of Representa-
tives of the United States of America in Congress assembled, 
SECTION 1. SHORT TITLE. 
This Act may be cited as the ‘‘Combating the Opioid 
Epidemic Act’’. 
SEC. 2. ADDITIONAL FUNDING FOR THE STATE RESPONSE. 
(a) FUNDING.—Section 1003 of the 21st Century 
Cures Act (42 U.S.C. 290ee–3 note) is amended— 
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(1) in subsection (a), by striking ‘‘under sub-
section (b)’’ and inserting ‘‘under subsection (b)(3) 
and the appropriations under subsection (b)(4)’’; 
(2) in subsection (b), by adding at the end the 
following: 
‘‘(4) ADDITIONAL APPROPRIATIONS.—In addi-
tion to the amounts transferred to the Account 
under paragraph (2)(A), there are authorized to be 
appropriated, and there are appropriated, to the 
Secretary, out of monies in the Treasury not other-
wise obligated, $4,474,800,000 for each of fiscal 
years 2018 through 2027, to carry out the grant 
program described in subsection (c). Such funds 
shall remain available until expended.’’; and 
(3) by striking subsection (f). 
(b) ACTIVITIES.—Section 1003(c)(1) of the 21st Cen-
tury Cures Act (42 U.S.C. 290ee–3 note) is amended— 
(1) by redesignating subparagraph (E) as sub-
paragraph (G); and 
(2) by inserting after subparagraph (D) the fol-
lowing: 
‘‘(E) Detection, surveillance, and treat-
ment of co-occurring infections associated with 
the opioid epidemic, including hepatitis C and 
HIV. 
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‘‘(F) Surveillance, data collection, and 
timely and consistent reporting on the number 
of opioid overdose deaths, including the inci-
dence and prevalence of co-occurring infections 
and toxicology reporting on the number of 
deaths where fentanyl or other illicit opioid 
analogs were detected.’’. 
SEC. 3. GRANTS FOR RESEARCH ON ADDICTION AND PAIN. 
(a) IN GENERAL.—The Secretary of Health and 
Human Services (referred to in this section as the ‘‘Sec-
retary’’) shall use any funds appropriated under sub-
section (b) to award grants for the purpose of conducting 
research on addiction and pain related to substance mis-
use. The Secretary, acting through the Director of the Na-
tional Institutes of Health, shall determine the amount of 
each grant awarded under this section. 
(b) APPROPRIATIONS.—There are authorized to be 
appropriated, and there are appropriated, to the Sec-
retary, out of monies in the Treasury not otherwise obli-
gated, $50,400,000 for each of fiscal years 2018 through 
2022, to carry out the grant program described in sub-
section (a). Such funds shall remain available until ex-
pended. 
Æ 
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