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(c) CONFORMING AMENDMENTS.—Title IV of the Pub-
lic Health Service Act (42 U.S.C. 281 et seq.) is amended—
(1) by redesignating subpart 3 of part E as sub-
part 19;
(2) by transferring subpart 19, as so redesig-
nated, to part C of such title IV;
(3) by inserting subpart 19, as so redesignated,
after subpart 18 of such part C; and
(4) in subpart 19, as so redesignated—
(A) by redesignating section 485B as section
464z–1;
(B) by striking ‘‘National Center for
Human Genome Research’’ each place such term
appears and inserting ‘‘National Human Ge-
nome Research Institute’’; and
(C) by striking ‘‘Center’’ each place such
term appears and inserting ‘‘Institute’’.
SEC. 102. AUTHORITY OF DIRECTOR OF NIH.
(a) SECRETARY ACTING THROUGH THE DIRECTOR.—
Section 402(b) of the Public Health Service Act (42 U.S.C.
282(b)) is amended—
(1) by redesignating paragraph (14) as para-
graph (22);
(2) by striking paragraphs (12) and (13);
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(3) by redesignating paragraphs (4) through (11)
as paragraphs (14) through (21);
(4) in paragraph (21) (as so redesignated), by
inserting ‘‘and’’ after the semicolon at the end;
(5) in the matter after and below paragraph (22)
(as so redesignated), by striking ‘‘paragraph (6)’’ and
inserting ‘‘paragraph (16)’’; and
(6) by striking ‘‘the Secretary’’ in the matter
preceding paragraph (1) and all that follows through
paragraph (1) and inserting the following: ‘‘the Sec-
retary, acting through the Director of NIH—
‘‘(1) shall carry out this title, including being re-
sponsible for the overall direction of the National In-
stitutes of Health and for the establishment and im-
plementation of general policies respecting the man-
agement and operation of programs and activities
within the National Institutes of Health;’’.
(b) ADDITIONAL AUTHORITIES.—Section 402(b) of the
Public Health Service Act, as amended by subsection (a)
of this section, is amended by striking paragraphs (2) and
(3) and inserting the following:
‘‘(2) shall coordinate and oversee the operation of
the national research institutes, national centers, and
administrative entities within the National Institutes
of Health;
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‘‘(3) shall, in consultation with the heads of the
national research institutes and national centers, be
responsible for program coordination across the na-
tional research institutes and national centers, in-
cluding conducting priority-setting reviews, to ensure
that the research portfolio of the National Institutes
of Health is balanced and free of unnecessary duplica-
tion, and takes advantage of collaborative, cross-cut-
ting research;
‘‘(4) shall assemble accurate data to be used to
assess research priorities, including information to
better evaluate scientific opportunity, public health
burdens, and progress in reducing health disparities;
‘‘(5) shall ensure that scientifically based stra-
tegic planning is implemented in support of research
priorities as determined by the agencies of the Na-
tional Institutes of Health;
‘‘(6) shall ensure that the resources of the Na-
tional Institutes of Health are sufficiently allocated
for research projects identified in strategic plans;
‘‘(7)(A) shall, through the Division of Program
Coordination, Planning, and Strategic Initiatives—
‘‘(i) identify research that represents impor-
tant areas of emerging scientific opportunities,
rising public health challenges, or knowledge
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gaps that deserve special emphasis and would
benefit from conducting or supporting additional
research that involves collaboration between 2 or
more national research institutes or national
centers, or would otherwise benefit from strategic
coordination and planning;
‘‘(ii) include information on such research
in reports under section 403; and
‘‘(iii) in the case of such research supported
with funds referred to in subparagraph (B)—
‘‘(I) require as appropriate that pro-
posals include milestones and goals for the
research;
‘‘(II) require that the proposals include
timeframes for funding of the research; and
‘‘(III) ensure appropriate consider-
ation of proposals for which the principal
investigator is an individual who has not
previously served as the principal investi-
gator of research conducted or supported by
the National Institutes of Health;
‘‘(B) may, with respect to funds reserved under
section 402A(c)(1) for the Common Fund, allocate
such funds to the national research institutes and na-
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tional centers for conducting and supporting research
that is identified under subparagraph (A); and
‘‘(C) may assign additional functions to the Di-
vision in support of responsibilities identified in sub-
paragraph (A), as determined appropriate by the Di-
rector;
‘‘(8) shall, in coordination with the heads of the
national research institutes and national centers, en-
sure that such institutes and centers—
‘‘(A) preserve an emphasis on investigator-
initiated research project grants, including with
respect to research involving collaboration be-
tween 2 or more such institutes or centers; and
‘‘(B) when appropriate, maximize investi-
gator-initiated research project grants in their
annual research portfolios;
‘‘(9) shall ensure that research conducted or sup-
ported by the National Institutes of Health is subject
to review in accordance with section 492 and that,
after such review, the research is reviewed in accord-
ance with section 492A(a)(2) by the appropriate advi-
sory council under section 406 before the research pro-
posals are approved for funding;
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‘‘(10) shall have authority to review and approve
the establishment of all centers of excellence rec-
ommended by the national research institutes;
‘‘(11)(A) shall oversee research training for all of
the national research institutes and National Re-
search Service Awards in accordance with section
487; and
‘‘(B) 
may 
conduct 
and 
support 
research
training—
‘‘(i) for which fellowship support is not pro-
vided under section 487; and
‘‘(ii) that does not consist of residency
training of physicians or other health profes-
sionals;
‘‘(12) may, from funds appropriated under sec-
tion 402A(b), reserve funds to provide for research on
matters that have not received significant funding rel-
ative to other matters, to respond to new issues and
scientific emergencies, and to act on research opportu-
nities of high priority;
‘‘(13) may, subject to appropriations Acts, collect
and retain registration fees obtained from third par-
ties to defray expenses for scientific, educational, and
research-related conferences;’’.