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SEC. 967. ADVANCED SCIENTIFIC COMPUTING FOR ENERGY 
MISSIONS. 
(a) PROGRAM.— 
(1) IN GENERAL.—The Secretary shall conduct 
an advanced scientific computing research and devel-
opment program that includes activities related to ap-
plied mathematics and activities authorized by the 
Department of Energy High-End Computing Revital-
ization Act of 2004 (15 U.S.C. 5541 et seq.). 
(2) GOAL.—The Secretary shall carry out the 
program with the goal of supporting departmental 
missions, and providing the high-performance com-
putational, networking, advanced visualization tech-
nologies, and workforce resources, that are required 
for world leadership in science. 
(b) HIGH-PERFORMANCE COMPUTING.—Section 203 of 
the High-Performance Computing Act of 1991 (15 U.S.C. 
5523) is amended to read as follows: 
‘‘SEC. 203. DEPARTMENT OF ENERGY ACTIVITIES. 
‘‘(a) GENERAL RESPONSIBILITIES.—As part of the 
Program described in title I, the Secretary of Energy 
shall— 
‘‘(1) conduct and support basic and applied re-
search in high-performance computing and net-
working to support fundamental research in science
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and engineering disciplines related to energy applica-
tions; and 
‘‘(2) provide computing and networking infra-
structure support, including— 
‘‘(A) the provision of high-performance com-
puting systems that are among the most ad-
vanced in the world in terms of performance in 
solving scientific and engineering problems; and 
‘‘(B) support for advanced software and ap-
plications development for science and engineer-
ing disciplines related to energy applications. 
‘‘(b) AUTHORIZATION
OF APPROPRIATIONS.—There 
are authorized to be appropriated to the Secretary of En-
ergy such sums as are necessary to carry out this section.’’. 
SEC. 968. GENOMES TO LIFE PROGRAM. 
(a) ESTABLISHMENT.—The Secretary shall carry out 
a program of research, development, demonstration, and 
commercial application, to be known as the ‘‘Genomes to 
Life Program’’, in microbial and plant systems biology, 
protein science, and computational biology consistent with 
the statutory authorities of the Department. 
(b) PLANNING.— 
(1) IN GENERAL.—The Secretary shall prepare a 
program plan that describes how knowledge and capa-
bilities would be developed by the program and ap-
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plied to missions of the Department relating to energy 
security, environmental cleanup, and national secu-
rity. 
(2) CONSULTATION.—The Secretary shall pre-
pare the program plan in consultation with the heads 
of other Federal agencies that carry out relevant tech-
nology programs. 
(3) LONG-TERM GOALS.—In preparing the pro-
gram plan, the Secretary shall focus on applying 
science and technology to achieve the long-term goals 
of the program, including— 
(A) contributing to the independence of the 
United States from foreign energy sources, in-
cluding production of hydrogen; 
(B) converting carbon dioxide to organic 
carbon; 
(C) advancing environmental cleanup; 
(D) providing the science and technology for 
new biotechnology industries; and 
(E) improving national security and com-
bating bioterrorism. 
(4) SHORT-TERM GOALS.—In preparing the pro-
gram plan, the Secretary shall— 
(A) establish specific short-term goals; and
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(B) update the goals with the annual budget 
submission of the Secretary. 
(c) ADMINISTRATION.—In carrying out the program, 
the Secretary shall— 
(1) support individual investigators and multi-
disciplinary teams of investigators; 
(2) subject to subsection (d), develop, plan, con-
struct, acquire, or operate special equipment or facili-
ties for the use of investigators conducting research, 
development, demonstration, or commercial applica-
tion in systems biology and proteomics; 
(3) support technology transfer activities to ben-
efit industry and other users of systems biology and 
proteomics; and 
(4) coordinate activities by the Department with 
industry and other Federal agencies. 
(d) GENOMES TO LIFE USER FACILITIES AND ANCIL-
LARY EQUIPMENT.— 
(1) IN GENERAL.—Subject to the availability of 
funds to carry out this subsection, the amounts made 
available under section 961(b)(4) shall be available 
for— 
(A) projects to develop, plan, construct, ac-
quire, or operate special equipment, or instru-
mentation; or
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(B) facilities at National Laboratories for 
investigators conducting research, development, 
demonstration, and commercial application in 
systems biology and proteomics and associated 
biological disciplines. 
(2) 
PROJECTS.—Projects 
under 
paragraph 
(1)(A) may include— 
(A) the identification and characterization 
of multiprotein complexes; 
(B) characterization of gene regulatory net-
works; 
(C) characterization of the functional rep-
ertoire of complex microbial communities in 
their natural environments at the molecular 
level; and 
(D) development of computational methods 
and capabilities to advance understanding of 
complex biological systems and predict their be-
havior. 
(3) FACILITIES.—Facilities under paragraph 
(1)(B) may include facilities, equipment, or instru-
mentation for— 
(A) the production and characterization of 
proteins; 
(B) whole proteome analysis;
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(C) characterization and imaging of molec-
ular machines; and 
(D) analysis and modeling of cellular sys-
tems. 
(4) FACILITIES
LOCATION
AND
MISSION.—The 
number, location, and mission of facilities under 
paragraph (1)(B) shall be determined in a plan pro-
vided by the Secretary to Congress before the construc-
tion of any such facility. 
(5) COLLABORATION.— 
(A) IN GENERAL.—In carrying out this sub-
section, the Secretary shall encourage collabora-
tions among institutions of higher education, 
National Laboratories, and industry at facilities. 
(B) TECHNOLOGY TRANSFER.—All facilities 
under this subsection shall promote technology 
transfer to other institutions. 
SEC. 969. FISSION AND FUSION ENERGY MATERIALS RE-
SEARCH PROGRAM. 
(a) IN GENERAL.—Along with the budget request of the 
President submitted to Congress for fiscal year 2007, the 
Secretary shall establish a research and development pro-
gram on material science issues presented by advanced fis-
sion reactors and the fusion energy program of the Depart-
ment.