‘‘(g) COORDINATING COMMITTEE.—
‘‘(1) IN GENERAL.—There shall be established
a Trauma Research Interagency Coordinating Com-
mittee (hereafter in this section referred to as the
‘Coordinating Committee’).
‘‘(2) DUTIES.—The Coordinating Committee
shall make recommendations regarding—
‘‘(A) the activities of the Program to be
carried out by each of the agencies represented
on the Committee and the amount of funds
needed by each of the agencies for such activi-
ties; and
‘‘(B) effective collaboration among the
agencies in carrying out the activities.
‘‘(3) COMPOSITION.—The Coordinating Com-
mittee shall be composed of the Directors of each of
the agencies that, under subsection (c), have respon-
sibilities under the Program, and any other individ-
uals who are practitioners in the trauma field as
designated by the Director of the National Institutes
of Health.
‘‘(h) DEFINITIONS.—For purposes of this section:
‘‘(1) The term ‘designated trauma center’ has
the meaning given such term in section 1231(1).
‘‘(2) The term ‘Director’ means the Director of
the National Institutes of Health.
‘‘(3) The term ‘trauma’ means any serious in-
jury that could result in loss of life or in significant
disability and that would meet pre-hospital triage
criteria for transport to a designated trauma cen-
ter.’’.
(b) CONFORMING AMENDMENT.—Section 402 of the
Public Health Service Act, as amended by section 208(c)
of this Act, is amended by adding at the end the following
new subsection:
‘‘(k) The Director of NIH shall carry out the pro-
gram established in part E of title XII (relating to inter-
agency research on trauma).’’.
TITLE IV—NATIONAL CANCER
INSTITUTE
SEC. 401. EXPANSION AND INTENSIFICATION OF ACTIVI-
TIES REGARDING BREAST CANCER.
Subpart 1 of part C of title IV of the Public Health
Service Act (42 U.S.C. 285 et seq.) is amended by adding
at the end the following new section:
‘‘BREAST AND GYNECOLOGICAL CANCERS
‘‘SEC. 417. (a) EXPANSION AND COORDINATION OF
ACTIVITIES.—The Director of the Institute, in consulta-
tion with the National Cancer Advisory Board, shall ex-
pand, intensify, and coordinate the activities of the Insti-
tute with respect to research on breast cancer, ovarian
cancer, and other cancers of the reproductive system of
women.
‘‘(b) COORDINATION WITH OTHER INSTITUTES.—
The Director of the Institute shall coordinate the activities
of the Director under subsection (a) with similar activities
conducted by other national research institutes and agen-
cies of the National Institutes of Health to the extent that
such Institutes and agencies have responsibilities that are
related to breast cancer and other cancers of the reproduc-
tive system of women.
‘‘(c) PROGRAMS FOR BREAST CANCER.—
‘‘(1) IN GENERAL.—In carrying out subsection
(a), the Director of the Institute shall conduct or
support research to expand the understanding of the
cause of, and to find a cure for, breast cancer. Ac-
tivities under such subsection shall provide for an
expansion and intensification of the conduct and
support of—
‘‘(A) basic research concerning the etiology
and causes of breast cancer;
‘‘(B) clinical research and related activities
concerning the causes, prevention, detection and
treatment of breast cancer;
‘‘(C) control programs with respect to
breast cancer in accordance with section 412;
‘‘(D) information and education programs
with respect to breast cancer in accordance with
section 413; and
‘‘(E) research and demonstration centers
with respect to breast cancer in accordance with
section 414, including the development and op-
eration of centers for breast cancer research to
bring together basic and clinical, biomedical and
behavioral scientists to conduct basic, clinical,
epidemiological, psychosocial, prevention and
treatment research and related activities on
breast cancer.
Not less than six centers shall be operated under
subparagraph (E). Activities of such centers should
include supporting new and innovative research and
training programs for new researchers. Such centers
shall give priority to expediting the transfer of re-
search advances to clinical applications.
‘‘(2) IMPLEMENTATION
OF
PLAN
FOR
PRO-
GRAMS.—
‘‘(A) The Director of the Institute shall en-
sure that the research programs described in
paragraph (1) are implemented in accordance
with a plan for the programs. Such plan shall
include comments and recommendations that
the Director of the Institute considers appro-
priate, with due consideration provided to the
professional judgment needs of the Institute as
expressed in the annual budget estimate pre-
pared in accordance with section 413(9). The
Director of the Institute, in consultation with
the National Cancer Advisory Board, shall peri-
odically review and revise such plan.
‘‘(B) Not later than May 1, 1993, the Di-
rector of the Institute shall submit a copy of
the plan to the President’s Cancer Panel, the
Secretary and the Director of NIH.
‘‘(C) The Director of the Institute shall
submit any revisions of the plan to the Presi-
dent’s Cancer Panel, the Secretary, and the Di-
rector of NIH.
‘‘(D) The Secretary shall provide a copy of
the plan submitted under subparagraph (A),
and any revisions submitted under subpara-
graph (C), to the Committee on Energy and
Commerce of the House of Representatives and
the Committee on Labor and Human Resources
of the Senate.
‘‘(d) OTHER CANCERS.—In carrying out subsection
(a), the Director of the Institute shall conduct or support
research on ovarian cancer and other cancers of the repro-
ductive system of women. Activities under such subsection
shall provide for the conduct and support of—
‘‘(1) basic research concerning the etiology and
causes of ovarian cancer and other cancers of the re-
productive system of women;
‘‘(2) clinical research and related activities into
the causes, prevention, detection and treatment of
ovarian cancer and other cancers of the reproductive
system of women;
‘‘(3) control programs with respect to ovarian
cancer and other cancers of the reproductive system
of women in accordance with section 412;
‘‘(4) information and education programs with
respect to ovarian cancer and other cancers of the
reproductive system of women in accordance with
section 413; and
‘‘(5) research and demonstration centers with
respect to ovarian cancer and cancers of the repro-
ductive system in accordance with section 414.
‘‘(e) REPORT.—The Director of the Institute shall
prepare, for inclusion in the biennial report submitted
under section 407, a report that describes the activities
of the National Cancer Institute under the research pro-
grams referred to in subsection (a), that shall include—
‘‘(1) a description of the research plan with re-
spect to breast cancer prepared under subsection (c);
‘‘(2) an assessment of the development, revi-
sion, and implementation of such plan;
‘‘(3) a description and evaluation of the
progress made, during the period for which such re-
port is prepared, in the research programs on breast
cancer and cancers of the reproductive system of
women;
‘‘(4) a summary and analysis of expenditures
made, during the period for which such report is
made, for activities with respect to breast cancer and
cancers of the reproductive system of women con-
ducted and supported by the National Institutes of
Health; and
‘‘(5) such comments and recommendations as
the Director considers appropriate.’’.
SEC. 402. EXPANSION AND INTENSIFICATION OF ACTIVI-
TIES REGARDING PROSTATE CANCER.
Subpart 1 of part C of title IV of the Public Health
Service Act, as amended by section 401 of this Act, is
amended by adding at the end the following new section:
‘‘PROSTATE CANCER
‘‘SEC. 417A. (a) EXPANSION AND COORDINATION OF
ACTIVITIES.—The Director of the Institute, in consulta-
tion with the National Cancer Advisory Board, shall ex-
pand, intensify, and coordinate the activities of the Insti-
tute with respect to research on prostate cancer.
‘‘(b) COORDINATION WITH OTHER INSTITUTES.—
The Director of the Institute shall coordinate the activities
of the Director under subsection (a) with similar activities
conducted by other national research institutes and agen-
cies of the National Institutes of Health to the extent that
such Institutes and agencies have responsibilities that are
related to prostate cancer.
‘‘(c) PROGRAMS.—
‘‘(1) IN GENERAL.—In carrying out subsection
(a), the Director of the Institute shall conduct or
support research to expand the understanding of the
cause of, and to find a cure for, prostate cancer. Ac-
tivities under such subsection shall provide for an
expansion and intensification of the conduct and
support of—
‘‘(A) basic research concerning the etiology
and causes of prostate cancer;
‘‘(B) clinical research and related activities
concerning the causes, prevention, detection and
treatment of prostate cancer;
‘‘(C) prevention and control and early de-
tection programs with respect to prostate can-
cer in accordance with section 412, particularly
as it relates to intensifying research on the role
of prostate specific antigen for the screening
and early detection of prostate cancer;
‘‘(D) an Inter-Institute Task Force, under
the direction of the Director of the Institute, to
provide coordination between relevant National
Institutes of Health components of research ef-
forts on prostate cancer;
‘‘(E) control programs with respect to
prostate cancer in accordance with section 412;
‘‘(F) information and education programs
with respect to prostate cancer in accordance
with section 413; and
‘‘(G) research and demonstration centers
with respect to prostate cancer in accordance
with section 414, including the development and
operation of centers for prostate cancer re-
search to bring together basic and clinical, bio-
medical and behavioral scientists to conduct
basic, clinical, epidemiological, psychosocial,
prevention and treatment research and related
activities on prostate cancer.
Not less than six centers shall be operated under
subparagraph (G). Activities of such centers should
include supporting new and innovative research and
training programs for new researchers. Such centers
shall give priority to expediting the transfer of re-
search advances to clinical applications.
‘‘(2) IMPLEMENTATION
OF
PLAN
FOR
PRO-
GRAMS.—
‘‘(A) The Director of the Institute shall en-
sure that the research programs described in
paragraph (1) are implemented in accordance
with a plan for the programs. Such plan shall
include comments and recommendations that
the Director of the Institute considers appro-
priate, with due consideration provided to the
professional judgment needs of the Institute as
expressed in the annual budget estimate pre-
pared in accordance with section 413(9). The
Director of the Institute, in consultation with
the National Cancer Advisory Board, shall peri-
odically review and revise such plan.
‘‘(B) Not later than May 1, 1993, the Di-
rector of the Institute shall submit a copy of
the plan to the President’s Cancer Panel, the
Secretary and the Director of NIH.
‘‘(C) The Director of the Institute shall
submit any revisions of the plan to the Presi-
dent’s Cancer Panel, the Secretary, and the Di-
rector of NIH.
‘‘(D) The Secretary shall provide a copy of
the plan submitted under subparagraph (A),
and any revisions submitted under subpara-
graph (C), to the Committee on Energy and
Commerce of the House of Representatives and
the Committee on Labor and Human Resources
of the Senate.’’.
SEC. 403. AUTHORIZATION OF APPROPRIATIONS.
(a) IN GENERAL.—Subpart 1 of part C of title IV
of the Public Health Service Act, as amended by section
402 of this Act, is amended by adding at the end the fol-
lowing new section:
‘‘AUTHORIZATION OF APPROPRIATIONS
‘‘SEC. 417B. (a) ACTIVITIES GENERALLY.—For the
purpose of carrying out this subpart, there are authorized
to be appropriated $2,200,000,000 for fiscal year 1994,
and such sums as may be necessary for each of the fiscal
years 1995 and 1996.
of the fiscal years 1995 and 1996. Such authoriza-
tions of appropriations are in addition to the author-
izations of appropriations established in subsection
(a) with respect to such purpose.
‘‘(c) PROSTATE CANCER.—For the purpose of carry-
ing out section 417A, there are authorized to be appro-
priated $72,000,000 for fiscal year 1994, and such sums
as may be necessary for each of the fiscal years 1995 and
1996. Such authorizations of appropriations are in addi-
tion to the authorizations of appropriations established in
subsection (a) with respect to such purpose.
‘‘(d) ALLOCATION REGARDING CANCER CONTROL.—
Of the amounts appropriated for the National Cancer In-
stitute for a fiscal year, the Director of the Institute shall
make available not less than 10 percent for carrying out
the cancer control activities authorized in section 412 and
for which budget estimates are made under section
413(b)(9) for the fiscal year.’’.
(b) SPECIAL RULE REGARDING FUNDS FOR SECTION
412 FOR FISCAL YEAR 1994.—Notwithstanding section
417B(d) of the Public Health Service Act, as added by
subsection (a) of this section, the amount made available
under such section for fiscal year 1994 for carrying out
section 412 of such Act shall be an amount not less than
an amount equal to 75 percent of the amount specified
for activities under such section 412 in the budget esti-
mate made under section 413(b)(9) of such Act for such
fiscal year.
(c) CONFORMING AMENDMENTS.—
(1) IN GENERAL.—Section 408 of the Public
Health Service Act (42 U.S.C. 284c) is amended—
(A) by striking subsection (a);
(B) by redesignating subsection (b) as sub-
section (a);
(C) by redesignating paragraph (5) of sub-
section (a) (as so redesignated) as subsection
(b); and
(D) by amending the heading for the sec-
tion to read as follows:
‘‘CERTAIN USES OF FUNDS’’.
(2) CROSS-REFERENCE.—Section 464F of the
Public Health Service Act (42 U.S.C. 285m–6) is
amended by striking ‘‘section 408(b)(1)’’ and insert-
ing ‘‘section 408(a)(1)’’.
TITLE V—NATIONAL HEART,
LUNG, AND BLOOD INSTITUTE
SEC. 501. EDUCATION AND TRAINING.
Section 421(b) of the Public Health Service Act (42
U.S.C. 285b–3(b)) is amended—
(1) in paragraph (3), by striking ‘‘and’’ after
the semicolon at the end;
(2) in paragraph (4), by striking the period at
the end and inserting ‘‘; and’’; and
(3) by inserting after paragraph (4) the follow-
ing new paragraph:
‘‘(5) shall, in consultation with the advisory
council for the Institute, conduct appropriate intra-
mural training and education programs, including
continuing education and laboratory and clinical re-
search training programs.’’.
SEC. 502. CENTERS FOR THE STUDY OF PEDIATRIC CAR-
DIOVASCULAR DISEASES.
Section 422(a)(1) of the Public Health Service Act
(42 U.S.C. 285b–4(a)(1)) is amended—
(1) in subparagraph (B), by striking ‘‘and’’ at
the end;
(2) in subparagraph (C), by striking the period
and inserting ‘‘; and’’; and
(3) by adding at the end thereof the following
new subparagraph:
‘‘(D) three centers for basic and clinical re-
search into, training in, and demonstration of, ad-
vanced diagnostic, prevention, and treatment (in-
cluding genetic studies, intrauterine environment
studies, postnatal studies, heart arrhythmias, and
acquired heart disease and preventive cardiology) for
cardiovascular diseases in children.’’.
SEC. 503. NATIONAL CENTER ON SLEEP DISORDERS.
Subpart 2 of part C of title IV of the Public Health
Service Act (42 U.S.C. 285b et seq.) is amended by adding
at the end the following new section:
‘‘NATIONAL CENTER ON SLEEP DISORDERS
‘‘SEC. 424. (a) Not later than 1 year after the date
of the enactment of the National Institutes of Health Re-
vitalization Act of 1993, the Director of the Institute shall
establish the National Center on Sleep Disorders (in this
section referred to as the ‘Center’). The Center shall head-
ed by a director, who shall be appointed by the Director
of the Institute.
‘‘(b) The general purpose of the Center is the conduct
and support of research, training, health information dis-
semination, and other activities with respect to sleep dis-
orders.’’.
SEC. 504. AUTHORIZATION OF APPROPRIATIONS.
Subpart 2 of part C of title IV of the Public Health
Service Act, as amended by section 503 of this Act, is
amended by adding at the end the following section:
‘‘AUTHORIZATION OF APPROPRIATIONS
‘‘SEC. 425. (a) For the purpose of carrying out this
subpart, there are authorized to be appropriated
$1,500,000,000 for fiscal year 1994, and such sums as
may be necessary for each of the fiscal years 1995 and
1996.
‘‘(b) Of the amounts appropriated under paragraph
(1) for a fiscal year, the Director of the Institute shall
make available not less than 10 percent for carrying out
prevention and control activities authorized in section
419.’’.
TITLE VI—NATIONAL INSTITUTE
ON DIABETES AND DIGESTIVE
AND KIDNEY DISEASES
SEC. 601. PROVISIONS REGARDING NUTRITIONAL DIS-
ORDERS.
Subpart 3 of part C of title IV of the Public Health
Service Act (42 U.S.C. 285c et seq.) is amended by adding
at the end the following new section:
‘‘NUTRITIONAL DISORDERS PROGRAM
‘‘SEC. 434. (a) The Director of the Institute shall es-
tablish a program of conducting and supporting research,
training, health information dissemination, and other
activities with respect to nutritional disorders, including
obesity.
‘‘(b) In carrying out the program established under
subsection (a), the Director of the Institute shall conduct
and support each of the activities described in such sub-
section. The Director of NIH shall ensure that, as appro-
priate, the other national research institutes and agencies
of the National Institutes of Health have responsibilities
regarding such activities.
‘‘(c) In carrying out the program established under
subsection (a), the Director of the Institute shall carry out
activities to facilitate and enhance knowledge and under-
standing of nutritional disorders, including obesity, on the
part of health professionals, patients, and the public
through the effective dissemination of information.’’.
(b) DEVELOPMENT AND EXPANSION OF RESEARCH
AND TRAINING CENTERS.—Section 431 of the Public
Health Service Act (42 U.S.C. 285c–5) is amended—
(1) by redesignating subsection (d) as sub-
section (e); and
(2) by inserting after subsection (c) the follow-
ing new subsection:
‘‘(d)(1) The Director of the Institute shall, subject
to the extent of amounts made available in appropriations
Acts, provide for the development or substantial expansion
of centers for research and training regarding nutritional
disorders, including obesity.
‘‘(2) The Director of the Institute shall carry out
paragraph (1) in collaboration with the Director of the
National Cancer Institute and with the Directors of such
other agencies of the National Institutes of Health as the
Director of NIH determines to be appropriate.
‘‘(3) Each center developed or expanded under para-
graph (1) shall—
‘‘(A) utilize the facilities of a single institution,
or be formed from a consortium of cooperating insti-
tutions, meeting such research and training quali-
fications as may be prescribed by the Director;
‘‘(B) conduct basic and clinical research into
the cause, diagnosis, early detection, prevention, con-
trol and treatment of nutritional disorders, including
obesity and the impact of nutrition and diet on child
development;
‘‘(C) conduct training programs for physicians
and allied health professionals in current methods of
diagnosis and treatment of such diseases and com-
plications, and in research in such disorders; and
‘‘(D) conduct information programs for physi-
cians and allied health professionals who provide pri-
mary care for patients with such disorders or com-
plications.’’.
TITLE 
VII—NATIONAL 
INSTI-
TUTE 
ON 
ARTHRITIS 
AND
MUSCULOSKELETAL 
AND
SKIN DISEASES
SEC. 701. JUVENILE ARTHRITIS.
(a) PURPOSE.—Section 435 of the Public Health
Service Act (42 U.S.C. 285d) is amended by striking ‘‘and
other programs’’ and all that follows and inserting the fol-
lowing: ‘‘and other programs with respect to arthritis and
musculoskeletal and skin diseases (including sports-related
disorders), with particular attention to the effect of these
diseases on children.’’.
(b) PROGRAMS.—Section 436 (42 U.S.C. 285d–1) is
amended—
(1) in subsection (a), by inserting after the sec-
ond sentence, the following: ‘‘The plan shall place
particular emphasis upon expanding research into
better understanding the causes and the develop-
ment of effective treatments for arthritis affecting
children.’’; and
(2) in subsection (b)—
(A) by striking ‘‘and’’ at the end of para-
graph (3);
(B) by striking the period at the end of
paragraph (4) and inserting ‘‘; and’’; and
(C) by adding at the end thereof the fol-
lowing new paragraph:
‘‘(5) research into the causes of arthritis affect-
ing children and the development, trial, and evalua-
tion of techniques, drugs and devices used in the di-
agnosis, treatment (including medical rehabilitation),
and prevention of arthritis in children.’’.
(c) CENTERS.—Section 441 of the Public Health
Service Act (42 U.S.C. 286d–6) is amended by adding at
the end thereof the following new subsection:
‘‘(f) Not later than October 1, 1994, the Director
shall establish a multipurpose arthritis and musculo-
skeletal disease center for the purpose of expanding the
level of research into the cause, diagnosis, early detection,
prevention, control, and treatment of, and rehabilitation
of children with arthritis and musculoskeletal diseases.’’.
(d) ADVISORY BOARD.—
(1) TITLE.—Section 442(a) of the Public
Health Service Act (42 U.S.C. 285d–7(a)) is amend-
ed by inserting after ‘‘Arthritis’’ the the first place
such term appears the following: ‘‘and Musculo-
skeletal and Skin Diseases’’.
(2) COMPOSITION.—Section 442(b) of the Pub-
lic Health Service Act (42 U.S.C. 285d–7(b)) is
amended—Section 442(b) of the Public Health Serv-
ice Act (42 U.S.C. 285d–7(b)) is amended—
(A) in the matter preceding paragraph (1),
by striking ‘‘eighteen’’ and inserting ‘‘twenty’’;
and
(B) in paragraph (1)(B)—
(i) by striking ‘‘six’’ and inserting
‘‘eight’’; and
(ii) by striking ‘‘including’’ and all
that follows and inserting the following:
‘‘including one member who is a person
who has such a disease, one person who is
the parent of an adult with such a disease,
and two members who are parents of chil-
dren with arthritis.’’.
(3) ANNUAL
REPORT.—Section 442(j) of the
Public Health Service Act (42 U.S.C. 285d–7(j)) is
amended—
(1) by striking ‘‘and’’ at the end of paragraph
(3);
(2) by striking the period at the end of para-
graph (4) and inserting ‘‘; and’’; and
(3) by adding at the end the following para-
graph:
‘‘(5) contains recommendations for expanding
the Institute’s funding of research directly applicable
to the cause, diagnosis, early detection, prevention,
control, and treatment of, and rehabilitation of chil-
dren with arthritis and musculoskeletal diseases.’’.
TITLE VIII—NATIONAL
INSTITUTE ON AGING
SEC. 801. ALZHEIMER’S DISEASE REGISTRY.
(a) IN GENERAL.—Section 12 of Public Law 99–158
(99 Stat. 885) is—
(1) transferred to subpart 5 of part C of title
IV of the Public Health Service Act (42 U.S.C. 285e
et seq.);
(2) redesignated as section 445G; and
(3) inserted after section 445F of such Act.
(b) TECHNICAL AND CONFORMING AMENDMENTS.—
Section 445G of the Public Health Service Act, as trans-
ferred and inserted by subsection (a) of this section, is
amended—
(1) by striking the section heading and all that
follows through ‘‘may make a grant’’ in subsection
(a) and inserting the following:
‘‘ALZHEIMER’S DISEASE REGISTRY
‘‘SEC. 445G. (a) IN GENERAL.—The Director of the
Institute may make a grant’’; and
(2) by striking subsection (c).
SEC. 802. AGING PROCESSES REGARDING WOMEN.
Subpart 5 of part C of title IV of the Public Health
Service Act, as amended by section 801 of this Act, is
amended by adding at the end the following new section:
‘‘AGING PROCESSES REGARDING WOMEN
‘‘SEC. 445H. The Director of the Institute, in addi-
tion to other special functions specified in section 444 and
in cooperation with the Directors of the other national re-
search institutes and agencies of the National Institutes
of Health, shall conduct research into the aging processes
of women, with particular emphasis given to the effects
of menopause and the physiological and behavioral
changes occurring during the transition from pre- to post-
menopause, and into the diagnosis, disorders, and com-
plications related to aging and loss of ovarian hormones
in women.’’.
SEC. 803. AUTHORIZATION OF APPROPRIATIONS.
Subpart 5 of part C of title IV of the Public Health
Service Act, as amended by section 802 of this Act, is
amended by adding at the end the following new section:
‘‘AUTHORIZATION OF APPROPRIATIONS
‘‘SEC. 445I. For the purpose of carrying out this sub-
part, 
there 
are 
authorized 
to 
be 
appropriated
$500,000,000 for fiscal year 1994, and such sums as may
be necessary for each of the fiscal years 1995 and 1996.’’.
SEC. 804. CONFORMING AMENDMENT.
Section 445C of the Public Health Service Act (42
U.S.C. 285e–5(b)) is amended—
(1) in subsection (b)(1), in the first sentence,
by inserting after ‘‘Council’’ the following: ‘‘on Alz-
heimer’s Disease (hereafter in this section referred
to as the ‘Council’)’’; and
(2) by adding at the end the following new sub-
section:
‘‘(d) For purposes of this section, the term ‘Council
on Alzheimer’s Disease’ means the council established in
section 911(a) of Public Law 99–660.’’.
TITLE IX—NATIONAL INSTITUTE
OF 
ALLERGY 
AND 
INFEC-
TIOUS DISEASES
SEC. 901. TROPICAL DISEASES.
Section 446 of the Public Health Service Act (42
U.S.C. 285f) is amended by inserting before the period
the following: ‘‘, including tropical diseases’’.
SEC. 902. CHRONIC FATIGUE SYNDROME.
(a) RESEARCH CENTERS.—Subpart 6 of part C of
title IV of the Public Health Service Act (42 U.S.C. 285f)
is amended by adding at the end the following new section:
‘‘RESEARCH CENTERS REGARDING CHRONIC FATIGUE
SYNDROME
‘‘SEC. 447. (a) The Director of the Institute, after
consultation with the advisory council for the Institute,
may make grants to, or enter into contracts with, public
or nonprofit private entities for the development and oper-
ation of centers to conduct basic and clinical research on
chronic fatigue syndrome.
‘‘(b) Each center assisted under this section shall use
the facilities of a single institution, or be formed from a
consortium of cooperating institutions, meeting such re-
quirements as may be prescribed by the Director of the
Institute.’’.
(b) EXTRAMURAL STUDY SECTION.—Not later than
6 months after the date of enactment of this Act, the Sec-
retary of Health and Human Services shall establish an
extramural study section for chronic fatigue syndrome re-
search.
(c) REPRESENTATIVES.—The Secretary of Health
and Human Services, acting through the Director of the
National Institutes of Health, shall ensure that appro-
priate individuals with expertise in chronic fatigue syn-
drome or neuromuscular diseases and representative of a
variety of disciplines and fields within the research com-
munity are appointed to appropriate National Institutes
of Health advisory committees and boards.
TITLE X—NATIONAL INSTITUTE
OF 
CHILD 
HEALTH 
AND
HUMAN DEVELOPMENT
Subtitle A—Research Centers With
Respect to Contraception and
Research Centers With Respect
to Infertility
SEC. 1001. GRANTS AND CONTRACTS FOR RESEARCH CEN-
TERS.
Subpart 7 of part C of title IV of the Public Health
Service Act, as amended by section 3 of Public Law 101–
613, is amended by adding at the end the following new
section:
‘‘RESEARCH CENTERS WITH RESPECT TO
CONTRACEPTION AND INFERTILITY
‘‘SEC. 452A. (a) The Director of the Institute, after
consultation with the advisory council for the Institute,
shall make grants to, or enter into contracts with, public
or nonprofit private entities for the development and oper-
ation of centers to conduct activities for the purpose of
improving methods of contraception and centers to con-
duct activities for the purpose of improving methods of
diagnosis and treatment of infertility.
‘‘(b) In carrying out subsection (a), the Director of
the Institute shall, subject to the extent of amounts made
available in appropriations Acts, provide for the establish-
ment of three centers with respect to contraception and
for two centers with respect to infertility.
‘‘(c)(1) Each center assisted under this section shall,
in carrying out the purpose of the center involved—
‘‘(A) conduct clinical and other applied re-
search, including—
‘‘(i) for centers with respect to contracep-
tion, clinical trials of new or improved drugs
and devices for use by males and females (in-
cluding barrier methods); and
‘‘(ii) for centers with respect to infertility,
clinical trials of new or improved drugs and de-
vices for the diagnosis and treatment of infertil-
ity in males and females;
‘‘(B) develop protocols for training physicians,
scientists, nurses, and other health and allied health
professionals;
‘‘(C) conduct training programs for such indi-
viduals;
‘‘(D) develop model continuing education pro-
grams for such professionals; and
‘‘(E) disseminate information to such profes-
sionals and the public.
‘‘(2) A center may use funds provided under sub-
section (a) to provide stipends for health and allied health
professionals enrolled in programs described in subpara-
graph (C) of paragraph (1), and to provide fees to individ-
uals serving as subjects in clinical trials conducted under
such paragraph.
‘‘(d) The Director of the Institute shall, as appro-
priate, provide for the coordination of information among
the centers assisted under this section.
‘‘(e) Each center assisted under subsection (a) shall
use the facilities of a single institution, or be formed from
a consortium of cooperating institutions, meeting such re-
quirements as may be prescribed by the Director of the
Institute.
‘‘(f) Support of a center under subsection (a) may
be for a period not exceeding 5 years. Such period may
be extended for one or more additional periods not exceed-
ing 5 years if the operations of such center have been re-
viewed by an appropriate technical and scientific peer re-
view group established by the Director and if such group
has recommended to the Director that such period should
be extended.
‘‘(g) For the purpose of carrying out this section,
there are authorized to be appropriated $30,000,000 for
fiscal year 1994, and such sums as may be necessary for
each of the fiscal years 1995 and 1996.’’.
SEC. 1002. LOAN REPAYMENT PROGRAM FOR RESEARCH
WITH RESPECT TO CONTRACEPTION AND IN-
FERTILITY.
Part G of title IV of the Public Health Service Act,
as redesignated by section 141(a)(2) of this Act, is amend-
ed by inserting after section 487A the following section:
‘‘LOAN REPAYMENT PROGRAM FOR RESEARCH WITH
RESPECT TO CONTRACEPTION AND INFERTILITY
‘‘SEC. 487B. (a) The Secretary, in consultation with
the Director of the National Institute of Child Health and
Human Development, shall establish a program of enter-
ing into agreements with qualified health professionals (in-
cluding graduate students) under which such health pro-
fessionals agree to conduct research with respect to con-
traception, or with respect to infertility, in consideration
of the Federal Government agreeing to repay, for each
year of such service, not more than $20,000 of the prin-
cipal and interest of the educational loans of such health
professionals.
‘‘(b) The provisions of sections 338B, 338C, and
338E shall apply to the program established in subsection
(a) to the same extent and in the same manner as such
provisions apply to the National Health Service Corps
Loan Repayment Program established in subpart III of
part D of title III.
‘‘(c) Amounts appropriated for carrying out this sec-
tion shall remain available until the expiration of the sec-
ond fiscal year beginning after the fiscal year for which
the amounts were appropriated.’’.
Subtitle B—Program Regarding
Obstetrics and Gynecology
SEC. 1011. ESTABLISHMENT OF PROGRAM.
Subpart 7 of part C of title IV of the Public Health
Service Act, as amended by section 1001 of this Act, is
amended by adding at the end the following new section:
‘‘PROGRAM REGARDING OBSTETRICS AND GYNECOLOGY
‘‘SEC. 452B. The Director of the Institute shall es-
tablish and maintain within the Institute an intramural
laboratory and clinical research program in obstetrics and
gynecology.’’.
Subtitle C—Child Health Research
Centers
SEC. 1021. ESTABLISHMENT OF CENTERS.
Subpart 7 of part C of title IV of the Public Health
Service Act, as amended by section 1011 of this Act, is
amended by adding at the end the following new section:
‘‘CHILD HEALTH RESEARCH CENTERS
‘‘SEC. 452C. The Director of the Institute shall de-
velop and support centers for conducting research with re-
spect to child health. Such centers shall give priority to
the expeditious transfer of advances from basic science to
clinical applications and improving the care of infants and
children.’’.
Subtitle D—Study Regarding
Adolescent Health
SEC. 1031. PROSPECTIVE LONGITUDINAL STUDY.
Subpart 7 of part C of title IV of the Public Health
Service Act, as amended by section 1021 of this Act, is
amended by adding at the end the following new section:
‘‘PROSPECTIVE LONGITUDINAL STUDY ON ADOLESCENT
HEALTH
‘‘SEC. 452D. (a) IN GENERAL.—The Director of the
Institute shall conduct a study for the purpose of provid-
ing information on the general health and well-being of
adolescents in the United States, including, with respect
to such adolescents, information on—
‘‘(1) the behaviors that promote health and the
behaviors that are detrimental to health; and
‘‘(2) the influence on health of factors particu-
lar to the communities in which the adolescents
reside.
‘‘(b) DESIGN OF STUDY.—
‘‘(1) IN GENERAL.—The study required in sub-
section (a) shall be a longitudinal study in which a
substantial number of adolescents participate as sub-
jects. With respect to the purpose described in such
subsection, the study shall monitor the subjects
throughout the period of the study to determine the
health status of the subjects and any change in such
status over time.
‘‘(2) POPULATION-SPECIFIC
ANALYSES.—The
study required in subsection (a) shall be conducted
with respect to the population of adolescents who are
female, the population of adolescents who are male,
various socioeconomic populations of adolescents,
and various racial and ethnic populations of adoles-
cents. The study shall be designed and conducted in
a manner sufficient to provide for a valid analysis of
whether there are significant differences among such
populations in health status and whether and to
what extent any such differences are due to factors
particular to the populations involved.
‘‘(c) COORDINATION WITH WOMEN’S HEALTH INI-
TIATIVE.—With respect to the national study of women
being conducted by the Secretary and known as the Wom-
en’s Health Initiative, the Secretary shall ensure that such
study is coordinated with the component of the study re-
100
quired in subsection (a) that concerns adolescent females,
including coordination in the design of the 2 studies.
‘‘(d) ALLOCATION OF FUNDS FOR STUDY.—Of the
amounts appropriated for each of the fiscal years 1994
through 1996 for the National Institute of Child Health
and Human Development, the Secretary of Health and
Human Services, acting through the Director of such In-
stitute, shall reserve $3,000,000 to conduct the study re-
quired in subsection (a). The amounts so reserved shall
remain available until expended.’’.
TITLE XI—NATIONAL EYE
INSTITUTE
SEC. 1101. CLINICAL RESEARCH ON DIABETES EYE CARE.
(a) IN GENERAL.—Subpart 9 of part C of title IV
of the Public Health Service Act (42 U.S.C. 285i) is
amended by adding at the end the following new section:
‘‘CLINICAL RESEARCH ON EYE CARE AND DIABETES
‘‘SEC. 456. (a) PROGRAM OF GRANTS.—The Director
of the Institute, in consultation with the advisory council
for the Institute, may award not more than three grants
for the establishment and support of centers for clinical
research on eye care for individuals with diabetes.
‘‘(b) AUTHORIZED EXPENDITURES.—The purposes
for which a grant under subsection (a) may be expended
include equipment for the research described in such sub-
101
section and the construction and modernization of facili-
ties for such research.’’.
(b) CONFORMING AMENDMENT.—Section 455 of the
Public Health Service Act (42 U.S.C. 285i) is amended
in the second sentence by striking ‘‘The Director’’ and in-
serting ‘‘Subject to section 456, the Director’’.
TITLE 
XII—NATIONAL 
INSTI-
TUTE OF NEUROLOGICAL DIS-
ORDERS AND STROKE
SEC. 1201. RESEARCH ON MULTIPLE SCLEROSIS.
Subpart 10 of part C of title IV of the Public Health
Service Act (42 U.S.C. 285j et seq.) is amended by adding
at the end the following new section:
‘‘RESEARCH ON MULTIPLE SCLEROSIS
‘‘SEC. 460. The Director of the Institute shall con-
duct and support research on multiple sclerosis, especially
research on effects of genetics and hormonal changes on
the progress of the disease.’’.
TITLE 
XIII—NATIONAL 
INSTI-
TUTE 
OF 
ENVIRONMENTAL
HEALTH SCIENCES
SEC. 1301. APPLIED TOXICOLOGICAL RESEARCH AND TEST-
ING PROGRAM.
(a) IN GENERAL.—Subpart 12 of part C of title IV
of the Public Health Service Act (42 U.S.C. 285l) is
amended by adding at the end the following new section:
102
‘‘APPLIED TOXICOLOGICAL RESEARCH AND TESTING
PROGRAM
‘‘SEC. 463A. (a) There is established within the Insti-
tute a program for conducting applied research and test-
ing regarding toxicology, which program shall be known
as the Applied Toxicological Research and Testing Pro-
gram.
‘‘(b) In carrying out the program established under
subsection (a), the Director of the Institute shall, with re-
spect to toxicology, carry out activities—
‘‘(1) to expand knowledge of the health effects
of environmental agents;
‘‘(2) to broaden the spectrum of toxicology in-
formation that is obtained on selected chemicals;
‘‘(3) to develop and validate assays and proto-
cols, including alternative methods that can reduce
or eliminate the use of animals in acute or chronic
safety testing;
‘‘(4) to establish criteria for the validation and
regulatory acceptance of alternative testing and to
recommend a process through which scientifically
validated alternative methods can be accepted for
regulatory use;
103
‘‘(5) to communicate the results of research to
government agencies, to medical, scientific, and reg-
ulatory communities, and to the public; and
‘‘(6) to integrate related activities of the De-
partment of Health and Human Services.’’.
(b) TECHNICAL AMENDMENT.—Section 463 of the
Public Health Service Act (42 U.S.C. 285l) is amended
by inserting after ‘‘Sciences’’ the following: ‘‘(hereafter in
this subpart referred to as the ‘Institute’)’’.
TITLE XIV—NATIONAL LIBRARY
OF MEDICINE
Subtitle A—General Provisions
SEC. 1401. ADDITIONAL AUTHORITIES.
(a) IN GENERAL.—Section 465(b) of the Public
Health Service Act (42 U.S.C. 286(b)) is amended—
(1) by striking ‘‘and’’ after the semicolon at the
end of paragraph (5);
(2) by redesignating paragraph (6) as para-
graph (8); and
(3) by inserting after paragraph (5) the follow-
ing new paragraphs:
‘‘(6) publicize the availability from the Library
of the products and services described in any of
paragraphs (1) through (5);
110
(C) in sections 480 and 481, by striking
‘‘the Division of Research Resources’’ each
place such term appears and inserting ‘‘the
Center’’; and
(D) in sections 480 and 481, as amended
by subparagraph (C), by striking ‘‘the Division’’
each place such term appears and inserting
‘‘the Center’’.
SEC. 1502. BIOMEDICAL AND BEHAVIORAL RESEARCH FA-
CILITIES.
Subpart 1 of part E of title IV of the Public Health
Service Act (42 U.S.C. 287 et seq.) is amended by adding
at the end the following new section:
‘‘BIOMEDICAL AND BEHAVIORAL RESEARCH FACILITIES
‘‘SEC. 481A. (a) MODERNIZATION AND CONSTRUC-
TION OF FACILITIES.—
‘‘(1) IN GENERAL.—The Director of NIH, act-
ing through the Director of the Center, may make
grants to public and nonprofit private entities to ex-
pand, remodel, renovate, or alter existing research
facilities or construct new research facilities, subject
to the provisions of this section.
‘‘(2) CONSTRUCTION AND COST OF CONSTRUC-
TION.—For purposes of this section, the terms
‘construction’ and ‘cost of construction’ include the
construction of new buildings and the expansion,
111
renovation, remodeling, and alteration of existing
buildings, including architects’ fees, but do not in-
clude the cost of acquisition of land or off-site im-
provements.
‘‘(b) SCIENTIFIC AND TECHNICAL REVIEW BOARDS
FOR MERIT-BASED REVIEW OF PROPOSALS.—
‘‘(1) IN GENERAL; APPROVAL AS PRECONDITION
TO GRANTS.—
‘‘(A) There is established within the Center
a Scientific and Technical Review Board on
Biomedical and Behavioral Research Facilities
(hereafter referred to in this section as the
‘Board’).
‘‘(B) The Director of the Center may ap-
prove an application for a grant under
subsection (a) only if the Board has under
paragraph (2) recommended the application for
approval.
‘‘(2) DUTIES.—
‘‘(A) The Board shall provide advice to the
Director of the Center and the advisory council
established under section 480 (hereafter in this
section referred to as the ‘Advisory Council’) on
carrying out this section.