"
Approved For Rp|pa«^ 2000/08/0?=
: <>tA^RDP96-G
A WORD ABOUT LASERS-—
——sor.To-Srate~Ta5e rs~
-a—giver
r«*onator is represented by two semi-transparent mirrors placed towards
1He periphery of the active medium.
.The
mirrors
force
the .photons
t0-aisp?Tse perp"irTdicularly
to their
. surface/
and frequently"pass
through-bhe—amplifying -medim— ———
:—
:————
:—
:—
:
they pass between the mirrors.
This process brines
about the
appo.aran c t
of
a powerful directed light impulse
in
a narrow waveband interval.
Since one of
the"-'
mirrors
is semi-transparent^
a very strong current
of “fari tliarrcre
goes
through: it im
a
perp'errdi c uriefr dire ctXoh In feThtibn
The solid-state,
ruby impulse
laser has found wide applications
in
biology and medicine.
The radiation generated by
a ruby laser has
a
WatfeTength
of. 6943 A,
"the power
o~f~TTa3Ia'fIoh may “vary wlthin~“wTde
-15oo-Jeiiles-j—The-^ttlization-o-f—microscope—lenses-enab-les—the—a-rea-of
-the—spoil, to be geducedL±o^en±Jis-jo£-a -squaxe-miuiroji*-
-
the present
-tlrcgr a constant plan of work
for ruby generators has been worked
nut.
The radiation energy of such
a laser comprises a
few milliwatts
(mW)
.
help of such' a laser it
is possible
to obtain non-thermal
-biological ef feets-of~radia Lion-;- an ~a wave length—af~6S'43~Arr~Howevgr7'
_the—ra<llation—area—of—solid-state—laser-s~is—large t -than—gas—lasers-,
(
i
« fc.
1 shows
the area of
the electromagnetic spectrum from
3oo-
12oo A,
that Is,
from the ultra-violet to infra-red band.
The emission
lines
are many , but
there are aiso blanjc spaces- (i.e.
tiv
fey§§s~of_Erope rties_we_re_ .discovered in quantum electron! cs
f with
tne aid of which It was possible
to cover the
whole band of the
511(1 obtain the generation of radiation on any wavelength
e
offlid~sec torr
Such propcrties—weTe discovered—-they turned
•~HLgjL_a narrow stripe,
stretched across
the
lower part of the
^^tte^axls,
In, this way,
the pumping of the dye
is accomplished
place
g^oTving cylinder
(drum)
which enables
the rapid change-over
from
to another «
The easy shifting of the generation line
is
D t aiheri Rv
fhe simple
rota t- 1 nn
rtf fks
wi tt ra/^F? r\ri al
Frv za tin rr" / C V
Approved-Ron Release 2000/08/07
: CIA.-RDP9a=QD7^Rfl0Q5DQi^800D1-D
tA,PCHft.lr-n r pp i^mr ?nnn ^.7nZ .ha :pnpQ^ nn7 ft7Pno^oonoooi o
yife-iGt ABOOT LASERS
-
'
—ewyr-lroar hunJi.fcrds' erf
„
—from—36oo A -to
lo , loo
mlllivrstta
-
,' and in any
_
i
t
^
I
*
•
—
*4
—L~L Vttt—
i-w
j-w /
i ww
«•/
^j^rww wj. t*-i-
j.xuc
j*/exny
of- a-width—
nf >T
<?n^L
Tn
.the—not -ta- d I s tanb-future-^ioiogists—wl-ll-have—an-
~
irt$3jvpea3i for the Induction of widely-differing effects
during
'~g V
mu~i ation and Inhibition of metabolic processes. Even now,
lase r
^3V5"Been constructecTbased on dyes
,
second:
bich.
a rapid spectrum change-
i~property “of
a laser will
doubt lessly—f-i^d-a—wide—applicet-ion—irn—the—r-upld—speotroscopy—of-
~ bio^objects , above—alL-ln—diagnosis-.
_
l-
~~S«sd conductor lasers
Up ., to
the
..present time.,
generation has been achieved on
7A
gemi-
conducto r
, crystals.
During the bombardment of semiconductors wi th
.
—
w*. J. NAAnwAi. w W A.
L.UJ. 5
w
ijeass of fast electrons , electron-hole pairs
are created in
them,
hign coefficient of amplification
r in semiconductors allows the
-
The
« vw«uv*wu
«*.**
w4*w
iVTinu
o
xi
. .are—heing turned out hy our indust ry
iST'G'f—
-semieonduettve—1-asers
-j
— * *
a
_
The main element of a semiconductor QQG
is
the semiconductor
diode with a thickness of o.l mm and an area
of. a few mnr.
The plate
""has
contacts bonded on two sides.
The" plate itself
is-'made " us of
—(P-type-)—conductance-.—The—gap—difference—between—them—Is—sal-led—%he-
—
nnrft on-
The thickneSS-O-f the ppme tfa-H on
rpginn
i g
enmowhprp
- 3 round
a thousandth of
a mm.
It
is
in. this
are a
that the generation
,°‘-..- rad:Latlon also takes place.
If., an electrical potential is placed
°
^-wt»LIuaLi
^
thenit: W
-11 -L
lead to "the
aggrahSizablen~‘ofTthe
-
uic lujciauiuu ui
tsiiexyy
j-li
uie
lorin DT
—i lght
'guante,—Semfcendueter—diodee-of-A-rsenie—&—GaHi-um-4GEAs hfkW ft?
-generated^ith
an
Impulse of high-level.
. current and -iiu-a_.tempa£ibngi
_or_J;iquld Nitrogen.
At present,
generation has been obtained at
_room_ temperature
as well.
The efficiency of the diode
is high"and
_5re ore tlcaI J-y. aPjP roache s
7o % .
"The
nuLnnfture-dimensTons of~the—lasers
,
grease with which
liyliL iddlation can be—madelatedy—the~different
pectra-ef-gene-rat-ionT-wi-l-l-undoubtedly^-i-n-the—future-make—them-into-
uv&nient-appa.ratns
for. .photobio logical
action.
Onr
in dustry produce
^Lemicondnoto^*
a wavelength of
9 loo A and a power of
x^wstt*
most monochromatic light
is ""gene rated, bygas
lasers.
The
generation—cf^oncchramatfcr-palarized~ coherent-i±gh±r-w±thr-the-acid
" f ~ f
"
tteat-guanturn—gene-rators—permits—the—se-lect-ive—aet-ivation
:
jr--metabalical -processes
i n plant organisms,
animals
end man.
~rr7^-^—^ggarch^_intQ the specific effects of laser light during its
rr~r—
biological objects did not begin suddenly.
How the
amassing'
on
the biological action of laser radiation took place
rehder~wiir-be~hble—to—di^cove~r^rr~the~fcrlTowing-paggsy
'
LlJ
O
LlJ
CO
o
n
f
wj
«C \
t-j
.
-
t
’
tC
E,JQ
ra
t-J
ZL
m^rm r 'BB |* 2ESZ2SM CXSSSI
l
B k-j-tJ Lwfcr .nJ
^|^5SS2^u02^^Sisaa*«sjSsiiaiiBa
I/*
*r^*
I PI!
he-n/e
Mil
jjm«i
tms&Eaiiza iniiacsaisEaaEasaiEsaaExaa
i
I?
S""ctral
lir.es generated
''P
on various
active mediums
, -uoj,
solids
X-axis
: Midi
1,2
MK, and. rounds •
..•**rpa.imwe JfHHRH,
reHepRpyeMue
JU3epoM
Ha
pa3JiK<tHUX
•mtnnux cmiil
Puc.
3.
BHeiUHHii ana re.nifi-HeoHOBoro Jia3epa, ofiopyaoBamioro
just
ofijiyReHiis kocthux nepenoMOB h pan.
II:
diagram of
an' optical quantum
ir "raduga" (rainbow)
(l)
ruby las
•
'
)
Ji-value
jsonator mirrors
( 2 ) Rvalue
°^° t\
X1
fbY
(3) impulse
-Ins.
;
lamps
(4(?ubv crystal
lamps
(4(?uby crystal
-
- iCcl lens
( 6 )nonlinear crystal douboling
t '10 frequency of
the
" n
o..
tie ruby laser
( 7 )
filter absorbing
the constant
frequency
*
«252BW3?S£S0
Ci:
:~j&
K
/*uc.
2. CxeMa orrrHHecKoro KBaHTOBoro renepaTopa «Pajiyra>:
»oro JUsep?
y^Tl. u ,?I®
MI,0,?r0
J ,5'0*
:
* - woayjiarop aoOpotnocth pyfixHosoro Jiaaepa: 1 — MMnr.ti.CHUt .munu hikupkk
•Oro
Jia,(pl
'.
J _1P
U
M "5'1 -1
3 — umiMHapHMecicj* ahh u:
t — hc.ihhcAhuA
KpiicTa.vi.
yaaaHa.iioiiiMA
xacToiy
Haay<<rHH«
o#Ky aHHM« re»*B*H"ili
TEh
,
I
0r "10lU * l01U
i-
H *
MeH JMeH < MH y*> lactory; t — aH<t>p>MiHOHHi* peuieiKa, noaopoT xoropoA juer
n.iaauyxj
rcMepamiH
orpaHxscxHoA
ofl.iacTH. 9- pt»o.iw.tpH u A OapaOaH
c
a kibctp mh,
janojiHtHHUMM
pacraopaMH
pal-
XMtHwx
upacMtcjicft;
JO — tuxoAHOe mpksao jumps
ha
*p*CMTe#ie.
‘JyQ^
:LnS,
V
’’
l on rotatod
»
Gives
s! ift
in generation lines witiir
. t
tl^iR|5^-067B7raK«>fe0Ot>BO©®1 -0
LjlJ
C£o
LlI
CO
Hit 3
w
[f«*w
V»
tfl
tu
L-1
fj
.
E.- 3a
rn
in
rove
mS|
-.——I *r*-dla tely—afte-r-^the—ore-ati-on—of-the—fi-rs t—©pti-cai-quan t-um-
iOOGi
rpsearch. work was dnnp on
fhP nnce<M t
....
ajuazs.
ipg f-ii
rpse-arm gorit was
, gone nn
rne_possihnn-< og Qf
'"~ts*ir.a then
for biological or medical purposes.
As
is known,
lassrs
“"“Vait radiation
at various
frequencies including visible or red
It gSIT
The
tirst lasers were made
tor tne red~part" of
the spe&ErunT
^out-.o tn e r -m visions or
researc n
.
&L.tne pxesent
-M m x mKy
Be-Xe .lasers-are—febe-jpost widely used in biology and mp.^r^A
.
The
r-a terlal presented
gi ves_an_idea about which routes researchers
“ta£<
after new sources ot light appeared,
sources o± high intensity—
• •
«
rw**wr»4*
V.
w**^s
wo-
U1C
(-uaj.au UCiiS U1C5
Q£
ldSfiT
X^CfU't—X’S
TIOt
•cr-. ly^ts—high—e-f-f-ieieney~±Hit—a^lso--±-ts—eharaeterts-t-ies—o-f—monochromati
As
a
^re-widei^ppM^^a^.ed^n^-' ^Jr^de^^f-^s^rc^s
^ finding
nnfr the
artion nf rnhy 1a^rg
nn
nf
*13htL«
Thus
,—lasers_have... fQund_wide application
as phntn-P^ qi1 i st-nr'-
.
tor the treatment of swellings.
«?VcuTa? SiS.Jf
.
?
£
f l
uu.,
A
| F
|
M1gachey-a-^ £^c^arried^^.,experiments
on
r
-fbblts
_ of the strain nHnrMn,
p=H 1 a tion was
e f fe c te
d
of a rybYrlaser whose wavelength was
6 94 3A~,~ the” Tencrth
Seconds .
The radiatiolTiHirg^i^orn-?12^
’3-t-jouleT^respecrtive lyr-rt-was
the»
r.o n |-rr
e^ergy level—o-f—radiat-ion—at—o-*-oc^2—joules—on—
<
nr
fnriiq
nf
1 " action^—the^totaL destruction. of
of th^rrr^Tggia
f--aS we— as
the
segments of the rods
and cones
—
retinal membrane could be
seen.
Layers of
' nerve
fiber
J
0t 10 dayS
affc*r what-waV-happenirig at~
~and-t£^S?IvKrff ^f^JTff-the-reyer-of-the-rods-and cones-
remairLW^f^
>f t
Jle-I
?ue
’le-i—of--the-externai-necleio-layer-.-—In - the
—
a^
di^opML^aa?es - ill-th&-Periiiuclear_ende
enercflrnatur^w
7?
fche_inerease_of_radi ati on
_^^d^?P_^59£_^as_noted .
Over
a period
‘ o
32Tty of Sinage Per
presented-itseTfas
~^ber-andSS
__4i2^^-ptgmentT-. -^-n-the-retinal-envelepe^-s ur-roandi-ng-the-ridge -
4-k=T ^P^a^—changes--jW^
e
ob s e rvecL
Data_found_in_ H tprafilra
„„
j
^
"avelenq^mA^ljEulge_len^^
-^~^--||^-_gne£gy_ range q^o2--l
joule,
creates changes
in pigmentary
dsaig-gg—
7tt-v>2r£»iCa^
anc* vascuj-ar envelopes and the degree of
~penetr»f«_i.t„
_
°Pt>rtioffa 1
to the-amoun tr~of'eriergy-giveirrwhirch
a?? lied
. wi
.th th-
Purpose of coagulating
-—
>Pk^LJ!
_f io?e *
.} U * A *
Linnik /
v 2 dined3nk07“'and~bthe rsT~l 9 s 9 ?
_€^~^J«ose^howing—the—recurranee— f—damage—around—the—zone—of
*
^^Lt^^Zril^7Sqt
i\^^Ker^^196a^“In-the-Sarne-Period -
laser
^9 69J—obae pied_pos sible__dama gin g_ef fects_of
'
Ht^d
P-gp-^s
o f
si ght.,. In the opinion_of_the autho^~
Ton5~-^n^re
V3n favo rable
action of
laser light is increased
in "condiT^'
J^'oT^row-il 1 umXna tidn-farnblent^Ti'ghti^ig~leve
®S-i?
corLdlt
as
M
UNSE^CXF-IED—ACT ION OF—LASER—RAYS—
ORGANI SMS
5~
Such
is
the—action of small amountsof stain
nnrrhinofl with
li-rr
t
y-
-SS€^r^e^a61 atLon
lb
-rSpoTts N.e.
Gamaieya,
a
selective disintegration of the mi tochon
an argon
msmsL
e sKin
untie
r
r=l»
;
uence of laser radiation.
At 3o-5o Joules
xud
_
a
••**%*ta*iVi* OUU
LIIKK—
as. foun
mmMgsmsm
lay
on mice
asicaj.lv not
mmm
lafTeliMfl
ation.
The most important parameters of
radiations
are in the
of energy,
energy
level/ power and intensity / w avelength, etc.
can b T*^ nCT about
a free-radical state.
The action of the
focused laser
"fad-i fetion was studied by them on freshly prepared human blood samples
-^e samples were then subjected to staining according to the
esp
r 1
fi lly
damaged
(dis inte_gx^tfidl_fe^th^_jcsdiaIAoilAgp uJLses.
of
a
rubv laser.
•
.
.
\
I
—
During investigations made of the EPR 'spectrum of
a whole see
series' ot brologicar^^mpT^T^^^l~e^~of~hoteworth7~farctrs^were
series
o
^revealed
were
cut Q£jL_an<LjpXaC-e_d_ln^_an_ampul,e_£.oj: EPR
, arLa£ysi-.jL_.
p i crmente d and white skin was
analysed applying
the EPR method.
^“^radiated skin, white
as well
as pigmented,
did not give out any
An—EP-R-s-ignal—was—also—observed—in—the—ecit^ocytes—of—pi-geons
.g- ar fhp<r snb -iectlon to _laser_lJj^t_xaillatibnJ^C^se.qrienjtly-^_jthe_
a c t ivi v of laser radiation on biological tissue s
leads
to the
appe’arance of
free radical states connected with- pigment clusters.
^
rnvoef^af^onR'have also beeh made on human skin.
The radiation
:r*srai
3 cUTip xSo—was.
tfU uuu wxuu
uiic
aiu
h
a. iiwj1
-lqoca. *
j- u
; a 5
i scovered—that—©nl-y—the—piqmented-skin—of--a—human--being~gives
: *
»
ci- sMp EPR signal.
The nature of this
signal
is
connected wi th
£2
;hc_ pi ament
mellonin.
One should not ignore the possibility o f
jZ
:be participation of multi-photon processes
in the biological effects^
; f~raaiationl
( L . Bl
Rubin ,
V3G9 )
.
.
~
“
£7
ronsiderable—intensity-of—multi-photon—processes—from—organic
fa
rclecules.^_jLnsofar_as_the^pps3.es.5_wXde_int.ena.ive_^sp.rb.tJLo.n_ajcsas_inQ
.hat part of the spectrum.
A definite probability exists
that under ra
he
action of laser light beamed on biological objects ,
multi-photon
'pro cesses-will take placel
“
'
'
'
"
“
T
in the visible waveband sectors,
light quanta are of extremely
ed quality from the point of view of the biological effect that
P roduce
(extremely different qualitatively)
.
For example ,
red
-
nd-viol-et—l-ight—can-br-ing—about-some—suppres sion—of—life—aoti-vi t
kBkwSmSuI
871'.
^
~
ojAngs
about the death- of
cells,-.
However,
under the action
; *—L?.se y_lf.ght. lethal consequences, can take place, both at
lo, 6 oo
*
r _
~ 1
as 5T3oo A.
“As” a matter. o£~facfT,
the
four-photon
° f -a~neodym±uiir"las’ex'xadiation., ~
. 1 o76oo~A'or
a two-
* IV '
~ ®i,sorPtlon—of—its- seeond—harmonic ,- 5 , oo -A-wi-ll-be equal—to
^
o£_J—quantum o f wavelength—d_,S5e. A.
Consequently^
in
t2*.1
1ar>--JSaltations of data obtained. - it is neccessarv to
ta
~—T.~*gL geration. the possibility of the existence of multiphoton
take
P56-00787RQQ050QQ8DM1-P
CIA-RDP96--0078
-----
Tf?~P r radiatiofl £ Hela cells with the
ald__o£_a^^yjJ:as e r
, ^ change
of-tHeTr_Tfis sue
s tructure were n^ticedrwnch
^rnoxphologrcs2rl7-^X)rrv^xgenir
-wl^h_^tie^hsn^es^n^the^rrac^e^~~~
neodymium-
, —and-r-uby-iase-rs-on-fe-is sue-culfcare-
... -cet-is ,
u*=
„ i
of author^ come
tn the
. cons
'! uaion
that mos t
rapid
flamag
ps
in the membrane structures of mitochondria- the endopl
.asmat_ c
^^E5tr4^om
G^tt
Y
the
suppIal»gfvr^cEIo5^f~B?IIS^^
jgser^
cuLture-.
TT
-
!
I
j_u _
Re^eotav^_wor}cs_have_been-.fiubJLish^-rnr nem 1 ag-the-possibxx^
Of obtaininq chromosome aberrations under
. the_actiOR-S£—wintermpt-e
T^r^i^Ionof"v^Fic^^waATeTengths .
He-Ne lasers 6328_A^ power
4y^i!-^^a-°Wrase-^s-^1
'BBo
A,
powef-r?5rmWT^ltrog¥H lasers.
is apparen
rs containe
Approved For Reloaso 2000/03/Q7-: eiA-RDP96^Q078?R00050008Q
^______UNSPECXFXED—ACTION—OE—LASER-RAYS—ON—LX3/XNG—QRGANXSMS—=-8
The
authors suggest
that coherent light
is photosynthetically
"more active than non-coherent light of the
same wavelength”.
Laser
-xrght
is
2o-3o '% more-eTfecttrve-than-that~
o
t a~whi
t
e~light~lamp~o r~
—O.P .-S achkov—(-19 99-)—el so—observed-a-sh arp—i-nc rease-
r
cnb jected, to.^URRl^enjLary_B_e-Ne
lase r, light.
I
of great interest is
the work that has
been done by A.I.
Semenova
"^nd V. A.
Singayevskiy
(1969)
explaining the biological action of
-
riow-intensity laser radiation on the living organism
(animais)
.
-ArX-r
^^e—Pn^feo—the—hr-omonal—reac^io:v-on-the—suprarenal-.—Radiation—activity
" Nd-H-
l asers.
The
.
PYDpriments conducted showed .that the action of He-Ne laser radiation
"of' constant activity
fi.e.
continuous wave t«or CW
‘Edsr~over
a
perio’d
>rings" “about hormonal-reSo tions
in-the-suprarenal"
regiuns
aianifesting—themselves—w±thr-the—deere ase—in—the—number-of
iozynophy-les—int—the—peripheral—b-l©Gd-by—3©=7©—%-,—the—increase—of
*
s
i
j
1 .
i
i
« _
4 _
n
it.-
-
es _
.
it...
i
i
and .the
decxSs e
in the content o f
lipoids in the suprarenal cortex,.
These changes obtain their maximum
fh P
suprarenal-Hfelgbt. by _ 2q-4q_%
value 15-2o minutes after radiation was initiated,
and-2-3 hours
after
the hormonal reaction-decre
-ased~to its-Initial
level":
radiation/
-The
return—to—the
-initiari—levei-took—more—than—5—or
6 hours—in
rat ?
w-i j-_h—a_weak—nenvous -s.yn.tem.—A—similar-ho rmana.1—reaction_was
. h a rdly noticeable_afte r_jnany_xadi atlons_with_impp1 s e__l ase rs .
Apart
from the hormonal reaction
a sharp incre ase
in the demand
fo r hydrogen
a single
ga's
“of 5o-loo% was observed.
A-I. Semenov shows that
laser radiation
is" equivalent
to-ftdny-rbpbatbd~radiahiohb—carriecT
-out
-with “the aid o f an OQG o f the
ruby—and-Nd-H:
-
. type-;
-Furthermore-/
A.I
.—Semenov -and—
V
. A .- Sengayveskiy—have—discovered_
that. by radiating the eves of animals with even low-intensity
gas
laser radiations, wavelength 6328 A, brings
about considerable
Changes“in“the
tone
functional changes
in the cardiovascular system,
or the vessels have been establish'ddi
After adaptation to
darkne'ss
,
pressure
:o._decxeas.e_,
^©-mm-Hg—sb*-)-.—Arterial—pressure—has- a—tendency-
_Sharp_ch.ange.s_in_th.e_actiyi ty_o f„h.ol ly.e.sterase s
take
place in the direction of its increase after the eyes
o f_ a rabb
i
t_ _have
been subjected:
to He-Ne radiation.
. A displacement* of Ca-Na
(Calcium-
'Sodium)
Balance
in the reticular tissue of~the eye has been notedr
"Accor ding to the-author s, -
>~all these
e ffects can-bring—about- changes
-in-the—parasympathetic—specter
- of
the—nervous—sy ste ra,—that—is-,—they-
-are_Qf
a vagotroplc characte x*_
Consequently,
as the various experimental work shows
,
' living
organisms
are able to react specifically to the action of laser
radxatxon ot different wavelengths
and intensity.
—gradual—evolution- o f
the—opinions—of—the—researchers—concerning
-the
.TTlPch .ani sms of
1 i ght antion and the greater Interest
shown
.to the problems of the photobiological non-thermal effects of this
_new form of radiation.
~~7io snow the perspective
of..
.
. *
this development in the utilization
he~physiulog±cal "effe cts
of. las er radiation—one—can
-it—was—possible
- to—get-^-acquainted—with
-the effects of
increa sed biologi ca l
activity
w.i th the aid of mnnn-
-Chromatic red light,
linearly polarized
(1I.M.,. Inyushln ,
19 65)
Since
then.,...!), years, have elapsed.
..As
. result of intensive work.
considerable. Jaateriai .conceml ng the biological- activity oi mono-
The-results "Of
' these investigations-are b re s^ented-irr
App
ed^drRfetSaSfc ^00708/07
: GIA^BP96-Q0787RQ005GOQ8€££l-0-
"
“
"
~
'
~
‘
‘ USIB DEPARTMENTS OWLY
:HAPT£R—
PHYSIOLOGICAL- ACT ION-OF-MONOCHROMAT-IG-POLARI-ZED--RED-
LJ GHT__ON_PE RIPH£BAL_3LOOD_AND__BLOOD-HORMLNG_OJRGAN S
-—
The
first experiments concerning
laser rays or other U.ght wave apparatus radiating monochromatic
Such research was neccessary for the evaluation of the specific
reachivene ss_of
, .the_Jb,lQQd-fQxming_Qrgans_£ub_gected
to ligh t
r adlaHnn
-of—definite- quantum-and-wave-parameters-i—They-were-to-open-the-^way
for-the wide use-oflaser radlatX&h-irT
- the "fTihlc^
During the total radiation of white rats and cats over periods
of_a_few jnainutfis_with_xioxicolie r.en.t_llght_af_inaximum_t3QCLrfi-4oo_&
over—a—period-of—lo-days-7—we—observed—rises—in—the-content—of-erito-
cy'tes~~~and leucocytes
(VTM^
Xnyush'fnT
19"65,
IT6 7)
.
On the 5th day
after radiation
the content of hemoglobin increased to more
than
units.
The_Jiumberio_f_eritxoj:yt.es__d.ecxease.d__sxjmdwha.t_QVjer_the_day_af.te 2
the—i-nitiation—of—the—radiation-/—and—as—the—time—went—on—progressively
Inc reased^from-^-million td~8=9~million ,
towards
the
loth day~of
the experiment.
Similar_reaciions_were_obseryetL_iit_dogs_wiiicii_we re_s.ubj e c.ted
— to—noncoherent—polarized-monochromatie—red—light—radiation—of—the
very-
safrie-iffEensity :
—
:
All our experiments were carried out as part of
a plan to make
-_a_gomp.aratlve_e.vaiuatlon_af_nQncoherent_and.. to ..a
. lesser,
v
. degree,
*
— monochromatio—red-tight-obtained—from—gas—d-ischarge—sources—and
“laser radiafioirT
Making use of
flouresence microscopic studies of
blood smears
, we came
to the conclusion that under the action of
ayeJLen
e—ther:
e
rats
,
amount of young forms of red blood corpuscles—reticular sites.
i
0 ^ bone marrow produetion—or-ertt-roey tes- wnder-the—action—of—stimuiants
!
if~is not enouah
Eo
t-.sk
SWWJfj 2000/08/07 VCIA-RDP96-00787
H¥SIOLOGICAL-ACTIOW—QE—MONOCHROMATIC—POLARIZED—RED—LIGHT-^-^.--
1.5-2
times,
already the
3rd day after the
mirj procedures of
monochromatic polarized red lTght activity obtained
.
from a
“honc^he tent “s'ource-With—Its-m'd^ImiCrt-fn~the— range~"o —6~4b"o—A-and
a~gas
-^ser—wavelength—6-32 -A-
In—additionr—the—laser-radtation-bringsr-
_about—qui-te-a—s-teep-increase—o£-eritropoetic—production..— ut
th e
_opj tropQ-e_sls_curve of differentiation has
a more wave form character
"in
terms of
time then in the case of the action of monochromatic red
"light issuing from a noncoherent source
.
The increased production of
"erXtrocy tes was observed in the
case-
cTf the
act! vlty-
o"f total laser
.
‘
cytesr-in—comparison—
Consequently,
the effect of monochromatic coherent polarized
light manifests itself as being physiologically
a more resonant
.
"cHaracte r
' than
the
" ribhcoKer"erft7
and-Its-effee
t
—pe"r'petda'tes“oVe
-lun ger "-periods" o f
Lime
a fter—the—initial—effects^—However;—the
-noncoherent—source—of—polar-ized-red-tlight— (-the—apparatus—for—thermal-
JjLgh£_xadiati.on_patent_nr,
2_4.5J3.iL5.)
^alsj^damonst.rates— a^j^tice.ab.ie
effect on the blood-forming organs.-.-
.
The condition of the marrow, "during the radiation. ofTliving
“creatures indicates that this-cay-factor-arc ts-as-a-s timulatonr-It
-was—also-noticed—that—after—a—singler-Sr-min—radiation—with—the aid
vasophi lic_and_pc.lychr.ome _e ri trcbl asfs__inc.re ases._on_the_aye.rage
by_5_r.lo"
When repetitive radiations were carried out 6ver
a period of
”
4 days,
an
*
increase of young eritroblasts was observed
(bazophili
-
polychrome-and-normob lasts
-
)-
The-number ~of—mire
-rocytes—Inc re a s'ed~,
——
e
specially-
—the—eozinophtle—by—a—factor-of—3—4— compared—to- normal
,
conditions-.
These—was—an—increase—in—the—activity—of-mitotic—ac-tivity
,
of
the .bone marrow cells.
;
„
Also,
considerable changes were noticeable
in
the_milt. (sple en)
In the initial stages,
a
filling, up
of" the spleen with hemolbrized
."
Blobd-tbbK-pTace";
and”With-"further-
'ca'diation'by- monochromatic "polarized
*
red—light—there-was—an—increase—in—the—number- of-young—lymphocytes t
I
which-demons-t-r-ated—the-exis-tence—of—the—activation-of -lymphopoesis.
!
>
(Y.J'L—Inyus.hiru_JL2_6 5_t_EJ_IL,__SmirnQy_1 9_6JIL,
j
To evaluate
the reaction
response of the spleen we applie d the
?
technique of biotic staining introduced and discovired' in their time
by 07N.
NaTsehov and
v. Y
ATexahdro”\T" (TST4oH
The--numerical
<e val uafioh-
uf—the—sorbic—stain—(neutral—red)—was—carried—out—with—the—aid-of
r
photoe-lec tro-golo ri me te r .—The—data-show -that—th e- maximum-ch anged—of
sorbic.ai_prope rti e s _is_ob s.e rved_frQm_the_3rd_fco__the_£th_day_a fte r_th e_
commencement of
the
2 minute
action of monochromatic polarized red
light.
The increase of sorbtion compared to the control group
'
(of animals J
comprised-
!from 3o- 4o
During—the-total
radiatrion by
r-shcrp^increase—of—sorbtion—already—af-ter—the—first-one—or—two-hours
(indices)
can sometimes be from 1.5-2
times greater than the norm.
At the same
time,
the consequent drop in
the amount of sorbtion staininc
e-ffee-ti-veness—of—response—is—determined^by—'the—influenee^-o-fr-the—degree
MWiTsTtla)Aii iblnimIS*JKTiTi
-Xidiation
During the action of laser light,
the response of the
ressed.
It is interesting to comment
f a
—Approved For Release 2000/08/07
: CIA-RDP96-00787R000500080001 -0
"PHYSIOLOGICAL action of monochromatic polarized red light
....
-3
;
t^lued-directly—on—the—isolated-spleenT^e also observed an increase—
the—sorb-t-ion—of—the—neutral—red.—Consequently-,—i-t—is—possible
fn
v^avp
a dlrprt Influence of ligh±_on_tha_or.qan-.
;
The
above
dat a demonstrate
the real effec t of the action of
j
monochromatic polarized red light,
extracted from
the, shortwave
.
section o
t" -the
~
~red"spectriim-OYrthe-prcrdaction~crf-b load-;
Sinrirlax
^
rn-nhtained~withr-the—aid—of—lase-r—tight-*
—In—both—c ases,
no
—ir-reversible—pathological—changes—of—any—sprt—were—observed .
—
—
Tn
the
reactlon_Q£_hiQo.c£-_forming_o r.gan s_w_er.e_studie
d
Fnr the most part in connection with the
activity
o f ionizin g
radlatlo i
•
^id sometimes ultraviolet light,
electromagnetic vibrations of an
—rrrErar
'
~EfgTr
_and_extremeiy high
frequency.
The materlarger preS'ehb
irrthis-sectlon—demonstrates—tha t visible~l±ghL,
especi.a-1-lyr-red-r1-1 gh t-,
|
_e-xer-ts—a—stimulating—influence—on—the—composition—of—peripheral—blood-
______and-blood=forming-organs..—_
—
,
,
—
B lood- forming reactions
in the organisms of living beings
.
.
;
subjected to long-term action of
laser, iight were studied.
In _such
*
-expirIf^€F-we~^s-erve'a~a-l)erro-drc-inhib-itive-e-ffeetron-blood-formxng-
which"was o f
a ~reverse—characte r.
:
r
“
'
_
Pn—our—
opinion-,—the—act-ivi-ty—of-
MRL—on—bloods-forming—organs
^nd—blood—genexated_by_a—laser or._Qthe r_li.ght_sour.ces—;take_s_B l.ace
both
direct ly and indirectly.
:
_—
,
.
,
In the
first case,
the
red light absorbed- by the porphirines
*
can bring about the lessening-
cTf the resistance
o'f^the"Older
~
•
eritrocytes-aTrd-thexir-disirrtegration—(-photodynamic—eifecth;
This
process—can—be-intensified-by—adding-photosensibilitizers—into—the-—
•
Tho
nrnrfiirt-s of disintearation_caiL-be_activated_b.y_the._blo.Qd
forming process
o f the ma rrow.
,
i
it
is known that native blood
(A.
Chi zhevsk iy
19 73 )
c ^~ rc
_u^ a “in<^
in the vesse si comprises
an-ordered-system!
Tn our-laboratory! ~
*
_
.
!
_
T X.
, « A «
o V-v i-\T.In
x.tr.
oeKrxemxscnev cauieu uuu
a
ocj-xco
— -
-
—that—blood—comp rises- a-system—with—labile—phases—and—.a-hrgh-degree
of cooperab j venp. cj g
-
Thp 'effects—of—laser. _radiation....can. .be
. realized
theough the blood thanks to which an accumulation and migration _of
absorbed energy is obtained.
During the direct action
ojf^OQG^
radiation on
-blood—exposed many times,
a
decrease
in
the
—number—of"abs orbed—methyl±ne-blue-was- observed-;—At- the-same- time>
—the—char-acte r—o f— the—sorbti-on—change
the i r— r-i se-or—falX-^^we re
.
i
i
j
«_ j>
_ i
j
A 4-
1 ^f.T
4 tn 4 4- 4 al
4’n/^4r*a+-T nn C
_
radiati on
as
a rule showed their rise,
their
fall.
They suggest that blood
is
sT liquid crystal eubstance
in which
1ight-indue e~s "multifarious—energy—proce s sesn
Consequentiy^
it—is
— pos slble -to- as s ume—that—the—fact—that—the—action—o f—laser—light—on
—blood
ip of
a
di rec .t natuxe has been . prq v.e dj.— B.1 oo.d—is—a—sub s.tan.ce
through which the transfer of absorbed energy to the ya^g^s_poln ts__of
the organism takes place.
At the
same
time,
the Indirect activity
of MPRL on
the
forming of-blood
takes place on account of the adti-
vation-of—the ~func tlorilrrg-o f~the-endoc rinat"ti ssues
(y 1 a:i ds )
above—
aHr;—the—hypophysic—(pituitary
Eds }—and—thyroid—which—have—a—direot-
—re lati-onship—in
re gulating—functions—
o
f blood—forming.
i
THE--REACTXON—OF-ENDQCRINAL—GLANDS-
- DURING—RADIATION-
BY MONOCHROMATIC RED LIGHT
"The ability of endocrinal glands
to react
to visible
light
^“Common-knowledge-;
1tr-has~beerr-shown-experimentally - that" un dex
;e—influence—of—'visible—tigh t-7—funet-ional- and-morpho-logic a-3r-ehanges—
‘ “ ‘
‘
‘
‘
" "
*
’ ,c hormones In
4-^.g blood
take s place
at the
front bottom of the hypophysis.
Apart
from that,
it
is known that the hormones
of. the
front bottom of—the..
IxUiH
Uiu
f
-*• W
< V.* * w
—
—
hypophisis not only control the gonadotropic action but also Influence
Se"<^"ti©-Ht—The—funcrtirorr^-f-the^hyral-d-graircJ-ts-
rec tly dependent—on—the—intensity—of—secretion—of—the—feireot-rophie
iemo^-t^ated that the tireotrophic
function of hypppMses_.Jji_frQ^s_
<*-
—-— “
~
1 —
—:
=
and toads
is
activated by the visible light from an incandescent lamp.
“There
are indications
that the hormonal activity
of. hypophises
is
-stimulated "By"re~d~rrgfrt~~(N . A.
Fop6^r~194 07-A^-Eimne—IS 5 Bretr-aDur
r
.
.
•<
.
v_ 1
_• _ 1
i
_ c c^ „ i. —
wuv
w — -v
—-
“ — —- — —
— —
•
—
•*>
research
into the
condlt
i
on of the thyroid glands of white.
rats after they had been subjected to
a single total dose of mono-
.
c hromatic red light radiation wavelength. f4oo K over
a. period of
2 and
5 "minutes';—Arrga'dy-r5-m±nutes-afteimthemtntroductioir-of-the-
-tsotopey—the—amount—o-f—radioactive—iodine—in—the—radiated—rats—was
-considerably—higher—than
the -control
group-
.
•
m
«
i
f
J
—
-No L much—has—been—discovered—about—the—bio-logical—e-f feets—of
‘
"
‘
.light-.
M—E .
Zeltner_has.
_The_msxim.u®_iodine_ab_sprp.'tion _is_ob s_eji^^^ii6^puxs_a f'te r_
introduction of the isotope.
In
that, period,
the difference between
"the control and experimental groups
reached” maximum amounts
.
and
.
~and_was‘—s taeisticaliy-signiflean
t
7~rOn
e
—daya fter-the-2 min radiatlonr
-the—condition—of—the—thyroid—glands-^
v no rmeli-z ecb—According—to—the—
I
j 1 t-r.
VUUUX
^
'
'
—'
—
-author-,—the—results—obtained—demonstratad—the.—activization—of—the
.
.
.
.
—
\
.
j
i
_
1. ±_
-thyroid—glan.d_arte r_a_s.in gle_dos.e_of ..mono^hromat ic_red_i i gh t_
radiation.
L.S.
Prihod'ko and M.E.
Zeltser
(196 7)
report of results
obtained on
the reaction of suprarena
to multiple radiations of
"white rays "(MFRI7)
of idehticar~wave"Iehgfh—in“experiraehts^to “discover
‘
‘
'
‘
'
'
-A-decrease—in—content—of
-aseorbiG-aeid-was—observed—which—points- to—the-hypofunction—of—the-
_s.uperrena .
After—the_s.in.g.le^Qses_Q f_tadiationjip_noti_cible_increas.es
in abscorbic acid
content we re observe d.
We reached. slightly different conclusions while examining the
"his tophysio logy-o
f” “the
super'rena'l
Ari analysis
o f~the
~s ubst'arrtive
-
“changes—in-the—supermen a- subjected—to-monochromatic—po-lar i- zed—red
-1 i-ght—and-gas—laser—li gh-t—enabled—us—to-dis-cover—a—complieated-
•
.
.
_
.
—
...
•
ii-vjltu
CU1U —VJGCS7
lasui.
ariyu u
CllC
vw—
—
— physiological
reaction of this
organ.
A fter_a__s_ingl e__ 2_min__mon o_chr.orna 1
re d light dose of radiation,
the stain sorbtlon usually decreased
which might point to
a decrease
in
function.
Towards
the
3rd day
~af€er~the~ initiation of double dose s“d f~Wdiation the
suprare'naT'
—
mlm X A -A- UXUUXW14
Vi.
uw UV XV
uwu
—— — - -
—- - —
— —£T
"sorbtion increased--abrratr-ho% 7—and towards—the
6 th day,—beg ins—fcxr
-approach-the-normal—leveb.—Laser—light-brings—about—a-more—rapid-
—rim. murX
iC-VCA w
±moc r
ane-gn xn—
w w
«
~
-lncrease_in snrVvUnn which
is
already observab 1e_3_a_min_aft er_a_s ingl e
_dos e of radiation.
Furthermore
,
a sorbtlon increase takes place
reaching an almost
2- fold value with
a successive decrease towards
Jtha
6 tK” day and
loth, day of action.
~
~ (NOfes~r~Mitoticierr-temporal—structure
in a dividing—cell
cre ating
the—movement-©f—chromosomes—towards 5 —its—poles-wbich—insure s-bheir
.
egual—di strihnti on hptwppn
the daughter cells .
:—
-e
r
-i throcyte:
red blood corpuscle,
erltroblast:
cell of bone marrow
precursor of red blood corpuscle. Nucleated, undergoes mitosis,
grad-
'
ually develops hemoglobin.
Eds)
Approved Fo r Roloaso 2000/08/0^^g l ^-|j^g|)^ffffifflysoa
TjfET'RESCTXON-OF'ENDOCRINAL~GL7VNT5S~DURTNG RABIATTO
f/nnseauentl-v-T— s-uch—an—important—gland-of—Internal-secretion-as—the
q uperrenal-h app.ena_to_b.e_
v_Subjected to more mark
e
d chan ge s_in
function under the Influence of coherent monochromatic light ,
63 28 A
,
I
in comparison with
a less monochromatic,
noncoherent radiation with fts
|
maximum at about-?4bd"Ar.
:
:
:
'
‘
—
The-stimulation—of—the—supe-rrena—is—indieated-by-bioehemfcalr-data-
weli—as—re suits—obtained—during his tological—and -h istochemical
.
rpsparrh
.
The data-
.prompted the thought that
lase r light is
ivHlizib le
as
an anti-inflammatory treatment .
At
'
the present
time,
our hypothesis has obtained the support inclinics dealing with' a
^Hole series "of ailments.
~
:
'
——Together with -doctor OrArr—Zevyalov—at—fche—ytlnis try-of—he aith
—hospital—of—the—Kaz akh—SSR,—we-
-obse r-ved—7o-patients-suf fe rin c
frnm
-rhg.nma.tni d..and
.. tranaformatlonai ^dlstrophic polyarthritis.
0.f
fh ese.
39 suffered
from rheumatoi d polyarthritis,
and
from trans-
formation distrophic polyarthritis.
Among those suffering from
rhe umatoid
Iyarthrxtis
-
;
there was
a p repbnde rence“Of~women~,
age's
25-6 5
y ears
-;—bhe-majarity,—Soy—having-suf fered- for-more—t^n-5-y ears-,
ipj^ey—^ad—many—times—received—treatment—in—clinics—and
.-health—resorts.
w-i-tho-ut—
iany—noticiable therapeutic
effect.*.
At reception,
the sufferers were
sub je
j
At reception,
the suffe rers were subjected to
a whole comp lex of
clinical, biochemical,
and X-ray examinations,
confirming the
—di agnosis
.
According to the-degree-o f
ac tTvity—fa cc20rding—fo—Nes te r'ov
)
—and~the~~pYO~cess~phases7~the
sufferexs-were-calssified—as—foilows :
— activity-of—first-degree—(-in—i54-,—activi-ty-of—2nd-
t and-third-degree
(
-i n
?4)
,
-a cute
exudative
... phase ,
in
1 patient ,
sjjb-ac.ute_ex.udatj.ve
proliferative,- in
and fibrose-sclerotlc in
5. patients.-
.
.
The sufferers received treatment from
a monochromatic red light
source
radiated-from
a prototype
He-N'e-Taser,
jlG^TS
, waveTeligth
5~32S~Al—Corrcurren tlyg
S' ~pat±ents-were—given—massage—and-phy s io-
— therapeutic—exe-rc-ises-.
The-rad-i af-j nn was .of
the general local character of activity on
the damaged joints
and reflexo-genic
i zones ,
applied in_physio-
therapy.
Radiation exposure varied from
to
3o seconds on each area,
and was selected according-to the ini€iaX~cohditioh ~o f~the’ ‘pa t'iehij
~ “the-phas'eS~an
_d~degree—of~process—activity^
7—
Some—patients—experience—a—sl-ight—vertigo,— sleepiness,—and
increased-perspiration—after—the first—2_or. . 3. sessions.
After_.adap.tatior
.— tO-.radlatlon ,
these symptoms disappeare d.
Afte r_ _3-_4__sess
i
ons
,
a
photore action was observed
in all of them.
In this period,
an increase
in_ pain
in
joints was observed
(in all the pafientsT the appearance
of swe 1 1ing~jofn bs~7
rin—3—pa tie‘n‘ts)'7_the—increase
in 'teinperature“(— 5.
— pati ents h.
In one~patienty—a—silght—i-nere ase—in-arteri-al—pres sure—was-
— --registered.—In—this—pe riod-y—radiation-was-prolonged,...but_w±.th
— decrees ed_expos ure .
In
2-3
day s,
all the
e ffects dampened down.
Towards
the end,
the
' pain
. sysdrome decreased in
35 patients,
the
exudative phenomena died down,
the
area of joint movement increased.
Mom xn g stiffness was
ie ss“jnarkecT;
“
Mo~marked changes—werepoted—in—the—hemogranu—The—ROE—became—
-slight ly-more—r-apid-iowsrd3-the-middle-of—the—course. , returning—
0rlgin a J—valm*
th e
end o f
therapy .
Towards
the mi ddle of
_tr.e_course,
some decrease
in lymphocytes
took place,
levelling out
ts en d.
The
S-.
reactive of white corpuscles did not change
-uring the rapy .
The
fibrodiriogen increased towards—the lcth-S’e'SS"iron'7
-w-ith-i-n—the—norm-.—The-contnet
e
:IcTn/gT:fii
ilN i]^MlTirtii .{iIiiimi’; fililililiM El
——
THEHREA'CTTOlT^F ENDOCRINAL GLANDS' DURING RADIATION
:
Out—of—39—patients-7—improvements’-were-observed-in~35.r' The
"
_pQlyarthrftis—and-muitlple-ancilos is— (bending -ability -of ’ a" joint —
'
_to_jQQye_as_a_r.es.ult_oJE_the_growLth_±ru-joint-swellings
Eds Y- and- in
patient with exudative prolife rative phase process, who violated
the
.
"regimen.
We did not observe any worsening of conditions of negative
"SKanges in the
joints of
a-single patXehtT.
——
MiiderT-_dei-ayed“resu'lts—wer€r'trac'ed“in“2'lr"patient's";
Of
- theniy 19
-w-i-th—e-xudat-ive—pro-li-ferative-change s-,—a-
..
-^-decrease-in- joint’ paind
_was—achieved,
an
increase—in—the ir—mobi-l-i-ty,—a-dec rease- i n - momin g
stiffness,
compared with the
inltiaL-Condi.tlon.
In__
these- patients
,
a good therapeutic effect was
.
obtained
a fte r the second session
"of treatment!
Af-first,
no improvements were observed in
2 patients.
L
w±-th—fibro-s'cleroticproces s "phase s 1
:
j
-The—-dynamics—of- -the—amount—of -^leucocytes
- and -ROE -in - the-second
I
i-nnrso nf tre atment
rH d
no t, nhange.—A_tendency—for—the -number of —
r
lymphocytes
to increase
towards
the
2 oth._day_ipf_..the_ procedures
. was
j
^“observed.
Apart from that,
a decrease in the_cpntent__of general
|
white albumin and aTpha-gTobuTins was observed.
The S-reactive of
r
white-corpus’Ices"-did~
-irof"~ihanger
T
T
~
—
-in—the—group—of—transformational-distrophic-polyarthritis' patients
were—L2-Jwomen_and—14—men.,—aged-be tween—35—--65-year.s- with-a-case
histo ry of mo re
than.
3__ye.ars..
_0f_them_2 l_with_ne’rvQ.
. os teo-arthrifeis
primary and
lo with distrophic damage
to joints
of_ different orgin:.
cliahging,
hormonal",
professional",
and
others,... Treatment of those
-patieirts-was_the-
, —same—as-those-suffering-froirTrheumatoid
polyarthritis-—-In—this—group-7—an—analagaus—phtotreaction was
" observed
However*—the.
j—pain—syndrome-dec-re ased- more—rapidly—than-in - those
suffering from rheumatoid_polyar.thri 6 tls .
Also ^.towards.. the_ end- of--
the course,
mobility was Increased
(area of movement)
.
There .were
improvements of greater or
lesser, degree
in all patients.
Hematologica
data-
.
re’flect-the tendency-Of-the~ROE~ to "dec reaseT
The number of
leucocytes—increased-somewhat—towards- the—middle
of" the ’course,’
the reaften-decreasing—to- -initial-val-ues-.—The- number
- of lymphocy tes
Increased within normal bounds.
...
A.M. Moshcheyeva of the ministry of health Kazakh SSR clinical
’
Hospital investigated-some
- biochemical’ indices of blood during
"
“"lasemra’dlrati'on-stimulation- irT'62~~pafients~suffeting” from inflammatory
processes-of—the-
^
_
/--uteral—appendages^—The~dynamics 'of
’ the white
r- — corpuscle—fractions—of—the- blood -serum-was—determined- with -the
_
use
o_f_A ._E_^_GurwjLchl5_method .
The_elec.trophoresis-..was_carried—out - in —
j
a bu ffer medin al -verinal
sol ution o f Ph
8.6 with
a
tension
f
(potential)
of ~3oo- V.
.
The data obtained was quantatively deciphered
[
on-an-FEKM~fpbb't'cFelectTohTmi c ros cope“?--E'ds 71
Concomitantly
,’ "the
j
quantity—of—general—serum-white-was
de te rmined-by- the- biure tic- method,
r
codified— y L . I .
S-lutskiy—(-1964-)—on—a-spectrophotome ter- SF—4A-.
t
LWotej
a^b.iureh_r.eaction_is__a__chemical—test_used— for-- proteins- in
solution.
Emp loys
copper sulphate
in
ak aline.. solution ,_which—gives
.
color with proteins
and with
a
few other substances-p-Edsl.
^
'i'he
first group of
31” subjects comprised patients with
an acute
-orm—of—chronic-inrftammatory-processes -taking-pla'ce~inr"tHe~
_uteral
appendages,—The—second—group-were—patierrts-with-inflammatory processes
ln_the_rhronjjC—S-tate- o f
illness-,—31—sub-j ects.
—r
.
In
•’ the contro l group of healthy
women-,., the _mean_.lay.el_ of..general
whi^e content was
in the region of
. 7.. 9o £ o,77
g
%. which corresponded
,
found Tn the literature.
J£n ~ the^fi rs t group,
the content of
i
9^e ral white sexum-of- the-blood-in-28“patient:s-w a —wi thih’"no rma 1
so 9- e ^ o
g % )
x