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Science Applications International Corporation
An Employee-Owned Company
Institutional Review Board
AGENDA
22 January 1993
1230 * 1300
Gathering
All
1300 * 1305
Welcome and Introductions
Dr. Rapmund
1305 * 1310
Review of Project Status (Administrative)
Dr. May
1310 * 1420
Technical Overview of Previous Effort
Project
1420 * 1440
Summary of Chinese Effort
Ms. Luke
1440 * 1500
Summary of Russian Effort
Dr. May
1500 1 1520
BREAK
1520 # 1700
IRB Review of Proposed Work
Project
1700 1 1715
Discussion
All
Other SMC ZZ,F*h^e, Bosch'
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ENCLOSURE 2
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Protocols for tho llso of Human Subjects
i. EEG MEASURES OF ANOMALOUS COGNITION
A. General Information
(1) Principal investigator:
(2) Contract in force:
(3) Project title:
(4) Responsible organization:
a.
Performing organization:
b.
Relation to SAIC:
(5) Begin date:
(6) Risk to human subjects:
Dr. Deborah Arthur and Dr. Stephen LaBerge
U.S. Government, Gient Private.
EEG Measures of Anomalous Cognition.
SAIC.
The Lucidity Institute.
Subcontractor.
1 February 1993.
MINIMAL.
None of the equipment used in the study or the
procedures for conducting the study are exper-
imental. The probability and magnitude of harm
or discomfort anticipated in the research are not
greater than those ordinarily encountered in the
performance of routine physical or psychological
examinations or tests.
B. Proposed Use of Human Subjects
(1) Research—purpose, and anticipated results:
Previous work has suggested that there are changes
in the electroencephalographic (EEG) activity of
individuals who are responding to remote and iso-
lated
targets.
Technical
difficulties
relating
to
data collection and/or analysis have hampered un-
equivocal replication of these results using anoth-
er
brain
measure
(magnetoencephalography).
This set of experiments is designed to overcome
these technical problems, as well as enhance pre-
vious
efforts
through
an
experimental
design
which is more comparable to standard AC experi-
ments.
The
first experiment
will
record
the
event-related
desynchronization (ERD)
of the
spontaneous EEG activity which occurs follow-
ing the direct presentation of stimuli that are iden-
tical to those used in standard AC experiments.
These ERDs will serve as a system calibration and
will provide data for an adaptive filter to enhance
the signal-detection ofERDs when stimuli are re-
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Protocols^MeYfle ot
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mote.
Hie second set of pilot experiments will
seek to record ERDs with remote AC stimuli.
(2') Human-use protocol:
There are two experiments as part of this study. Hie first is a replication of a traditional ERD
study where
the
stimuli
are
selected from
our
set
of National
Geographic magazine
photographs. The second experiment is an attempt to observe ERDs when the same stimuli
are isolated from the subject.
Each of these experiments will begin in pilot form. What is presented here is a typical ap-
proach; however, any others that may be tried will not differ from that, which is presented here.
a.
Calibration of System and Subject ERD:
Subjects will view National Geographic pictures,
which are presented on a video monitor.
Each
subject will view approximately 30 pictures pres-
ented sequentially for one second each with an in-
terstimulus interval of four seconds. EEG will be
recorded from 15 channels over the occipital and
parietal cortices referred to the right
ear. EOG
electrodes will be placed laterally and supraorbi-
tally to the right eye. An average visual evoked
potential beginning two seconds prior to the stim-
ulus onset and continuing for two seconds after
the stimulus onset will be collected for each stim-
ulus
presentation.
Comparable
unaveraged
epochs will also be collected for off-line proces-
sing.
b.
EEG and Anomalous Cognition:
A major improvement over previous studies in
this experiment is to obtain a behavioral mea-
sure ofAC as well as any potential ERD indica-
tion. The main idea is to create conditions that
are as favorable as possible to illicit good AC
functioning, yet do not produce significant mo-
tion artifact for the collection of ERDs.
The same stimulus set that was used in experiment
a will be used in this experiment The rate of stim-
ulus presentation
will be randomized between
five and 15 seconds.
The recording procedure
will be similar to the ones in experiment a. In pilot
experiments, an optimal protocol will be deter-
mined for use in a formal experiment. In the pilot
approaches, we will record ERDs: (1) during a
standard AC session while a receiver is writing
and drawing, and (2) using a counterbalanced ran-
dom protocol to conduct a standard AC session
without EEG, followed by an EEG session where
only AC mental activity is used to access the same
target (i.e., without writing and drawing).
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