_!pHE—REAC-T-ION—OF—ENDOGRINAL—GLANDS—DURING—RADIAT-ION-
The concentration
o f serum white
corpuscles on the
ave rage compris ed
“"7.69
± o.o96
g
% which was somewhat below the indices of the control
-groupT
IT~the indices of
the general white corpuscles of-blood serum
^iTi-rrotr'show—sirntrlar—rises-
;—then—the~separaterwhi te'-corpuscle—fraction
showed-marke d—changes-.—White—corpusc le s-were-ob s e rved-in-only—five—
MiTtral
mean index of albumin content in the men of
the control
group compr i s e
d
4.68 + o.o42
g
%,
then in the group with acute chronic inflammatory
processes it was considerably Tower:
3T98 +
o.9~8
g
%
at P
less
than
_THE EE&CTXQN_QE1 _END0CRINAL—GLANDS -DURING—RADIATT0N\TT-5
frac tlon_cQnteiit5
. wp r-P
.K,ar ,c
_
-hes pl-ta~l—carrled~o
f
' h-e-al^-/f
2^^S^-cllnical
_3o—suffering—from—acute—form o f~ch rcn
^-8-—1Ajl°ZL^»^n3png_thern
jUie__ute_ral_appendaQea_and^ftZf_5^m!^
^amm
tory processe s.^irt
J4wome^suffe^d^_|^ii^a_tvto-s±ded_inf1ammatow—
.
_
Tf^rsui
-r^ildi^aTiTbnageTal
-frofti
2 o-4 3 years.
ax
Eds *~*—Their—ages—varied—
from
5 months
to. 17 vears
th q
Chills,
In
7,
causes
cniil^ nnt^f
was.
'
clinic,
theycomp 1alned of general d^f^n^ Pr^^^^ 1tgr±fl^
appe 1 te ,
irritib ill tv'.
ne rsoiTTATTr,
J-ca.enceea ^_Lack-of- sleep-and
tJie-lower-sector^-of^lAiofflaoh—aH3 TSsf—
'MS-EeJiodl c~patns In
body
a
Ed^>
All the patients were subjected to clinical
an^
4.
laboratory—tests~~duria'g~tKe~€Hir:^^~~^t^^
C1:L ~^v
some
3 ™es
carried-out-^ccording-to-a-method-wcrif^d-3-^—
B^-J?Las
radittio.rLwas_carrSdIo^n
^
OUt7y us ‘*
• Laser light
:_ji5z25 -
known^a\rg5^'arTl^^nTs^varIed~ai-
i
?
H?~
re;£l£J:?9e“ic"^zonss 'and
organ i-sm-to~the-the rapy^appTfe d"
re.ac.tioa of
the
*-« -wii—
daily
at exactly the
same
,t°j^pr0cedQre^hlc^e^rcarrTeaiir-
sub?ed!^^
"C^duress
the acute- s t ag<§ of chrohl^~in f
—fourth—to—loth-pro—
utera-1—appendages—showed—arr—f
.P-r_?pesses_qf ,_the
in-Pain^Jielow-the-sfnmacK^^.^i ®" 11 ln
?e”® ral condition;
a decrees
temperature
DurinaTM^M
J-lornsy-normaiiaatrorr^TDddy
‘
out to be
insicmificanl-
'"
"'
statistically- -it-turned
in'the-^tndtcea^ofs^ead'trve-
—ere-alSO_obta ined'by—us—
— ^^rapy^-together^i^h^^SSL-
Towards_t.'ls_SI1a_0£:
^,ec rease—in_the-index-o.f—
-1
->~-i
ca-^effeet ,_a genuine
—which^pointed
to the_cuDera.tioJ?ii acid-was-0bserved in the
25 pati
as
the S-rea^tive albSn^e^tf"^th^-inflammatory-processT-As-ra'T^
'
‘diver^nces“^f^ti~coiIti^n~r^M?r??J1Cerne?r We^3id ~not~^tscove^^^
womexrr
—- content Practically speaJcjng^Lii_.aJiy_o£_the-hea^
—.patlents^^f
bhe
fTrs
"^dourse
o f~th¥rapv of
bter^_appenda5iStl!0m^CtIl!^±rt^^r^5^^^^ processes
in
the
a Partial effect bv
JT+Tu ta^t^raPeuti'e_effect-was-attained~bv-T7
MKb did "not
-
ObtaTj^hh^fwf e £feft-nated-in--5-wsmei>,
13-patimts--
-^ake-anrepSaH^dblrr-^l^f^—
:»g*^-S-«fect-«er^eCcm.ended-SS!l-
hay^~-j—-
e ettect was
absen t
in h
Wh,
i
t
°
re ac
(Noterfrom~i:hi~G
'reeh~
fa *!es ?P?rativa
fc—Q ^apy-was neccessary-
* A8Bf6^§a¥apffet^sss^e/e®^
a ; : —______ ___-THE—REACT ION—OF—ENDOCRINAL—GLANDS—DURING—RADIATION3<7~6 { ___Out of 38 patients in the chronic stage_of_illness.,._towards_the [Toth procedure, 22 were observed to undergo a cg __worsening of general _ condition, and intensification of pain below the stomach and loins,an. [___fetveasein—albumin;—tack of steap-and-acpotttes ftom ga trenthee ~feverish—body—tempe rature—appeared.—___________________- [—sub= s_pointed to the intensification of the inflammatory—proces of the uteral appendages. After the first course of treatment 27 out. | —¢F-the 38 women noticed a disappearance of the inflammatory state rand pains in the regions of the uteral appendages. The latter were 7 eat palpation.._7 pattents obtained a partial Gffect, a certain __—_deecrease—in the dimension-of—inflammatory—formation£-of-uteral—appendage. | _ and a decrease in_pain_at-palpation.:—No_e ffect_was—_noticed—on-—4—-patient: T When analysing the indices of sfal acid_in the process_of_therapy, a [noticable increase towards the loth procedure was established. In in __ Some patients, it lasted until the end of the first course of therapy- 1 ae 7 P Tess than ©.66L) which ~~ |-—pointedto—the-aggravation-of—the—infl ammatory—-process.—Tfowards-the——_ i middle of therapy, the S-reactive_albumin_indicator_had-a_tendency—— . | to increase somewhat, however, statistically, it turned_qut_to_be____ ["~ansignificant. 11 Women in the group which did not, obtain a full effect underwent a repeated course of laser radiatton with. good results. Investigations made—into the dynamic changes of nénograms in the-process—of—laser—light ©—th : “Tut LAr fe treatment, the réd blood diagram did nof€ change in either of the patient groups.—No-significant—increases=in-the- quantity—af-leucocyte-contnet was_established.—_The_reactive—index-of—eritrocytes—sedimentation— ROE) varied somewhat_during the_process_of treatment, however, these changes were within the bounds of physiological norms. When dealing with the white blood diagram, it is neccessary to * ~ Observe that towards the end of treatment, the quantity of neutrophyles —definitely—decreased—in pattents-with -chronic-inflammatory processes—in -—-theixr—acute—states —_——in_the_majority of patients of both _groups,..together.with-their— _ ..¢linical recovery,_a certain increase_in. eozynophyles_was observed... (Note: eosinophil leucocyte: polymorphonuclear leucocyte of vertebrates, "containing granulés staining in acid dyes such as eosin. In human | ~ beingsnormatly- ahout-2=5-8 ofall teucocytes” but becomé tiwGh” increased --—in-certain—parasitiec—in fections;—and-in-allergies-—-Eds} » —____The, changes_taking place corresponded_to-the—clinical ~recovery—— Of the patients. We investigated the long-term results of laser radiatic __therapy in 53 patients over a period of 5-12 months. Over the period mentioned no symtoms whatsoever.“ | <were 7 “observed —hr-any—of-the women,—pointing—to-the existence of an in flamniator “—p rocess—whieh—is—confirmed-by—elinical—investigations—of-data;——_ 7women who earlier suffered from steril ity,—_became—pregnant ——
pproved~For R'eie3Sfe2000/08707; ;C1A-RDp9S--00?a?ROO05
_jy_fch e
lQc a3^_ag_tlPJl—P_f_P-blarlzed MPRL
(monochromatic polarized
red
—iigh'M—wavelength—from—6-3oo-64oo—A-©n—skin—wounds—(-lesions-)—distribute.
O T1
Hi&-ear- of
a
. rabbit ,—a-charac teris tic_his.tologic_change—was
nhserved which pointed. to
the. stimulation of regenerative processes
.
This was done by B ,L;Koritniy and collaborators
in 1967.
Although
the
"“experiments were carried out on the same rabbit,
one ear toeing
-purposes—of^-control-,—distinct-morphological—changes—manifested—
y -Hrh was subiected~ to. radiation,
already within- a period of three
hours,
a. larg.er number of neutrophyles began.to appear than in
“the control-ear,
i'n succussfve periods ,
an increase-in the
in-
“tensirty-"of phagocytris was-
]!" tedvThe-bacteriai—flora-composed
-^f—dipio—and—tetra—eoce-i—almost—ent'i-re-ly-phagocytosized—in—the
.wound—exudate .
.. A more -
-
. rapid_healingJof_.woundsL_was__r:egia.ter:ed_when
-nnochromatic polarized
red' light radiation was
applied.
At the
basis
of the observed
: effect,
according
to the authors,
lies
the
1c tivation o?
the tran s formation of^Fo^rtXes-In-the-skin durIrig
- tbe“ To ca:r~ac tivi"ty~of~polari‘zed~re
d
-1ighbr-—
—
A large—eyc-le-of—work—was—earr-ied—out—by-prof-r—D-ri-^Kori-tn-iy-,
—
explaining—some_of—.the—morphologi-cal
. and-his.tologlcal_displacement,s_
ir.
the
auto-transplantation. of. the skin of a rabbj*b during the action
cf monochromatic red light;
It
is
curious
th^it during macroscpic
cose rvations"7
a very"“d"fs""fincF"diffe re nc'e“TrTffie
bo~n"dlrfion-of
transplanted-skin—Cshxeds)~: is - engendered'wrth -hardly—noticeable
c n i t ter-lings—ft-ripej—intens tines-)-*— During-h isto-logical-1ri a-ls
characteristic-
hajages...man.ifested-jthemsel-ves .already
1 in the course
zi
the
first days
~ after
. radiation was
initiated .
The leucoctytal
-ill
in
the radiated skin shreds was considerably more prominent
:r.
comparison with-those that”were not~ra"drated .
Durihrg-the-activity'
. f
r onochromatlc-po"larized~xed~light—an-accelaration.-of inflammatory
process- phase—changes—©eeur-,—and—the—proliferation—of—fibroblastic
flec-.onts-ls—stimulated. Characteristic
is
the, absence—,Qf_f ibrose
: o -r Ishments. (nutrients)
which’ in unradiated auto-transplants
a;
4 ear_as whole
. separate areas.
"""J
J
~;e_same
time,
on ths“backgrouhd~6f—the"stimul'at6Dn 'of connective
*
-
k
oo
elements ,
the-rs-epidermation-of—the—-radiated—transplant
'
•
' '* s
down — Only towards-the-^twentieth—day—does—the—whole—transplant-
-
•- ; r.
i. • • c ome-cove red—by_th.e_epidermis_createcL
In_r.adiate.d_trans plants
*
'.-n ts ..of
the _ epijthe 1 ia _along_thec©©nft6 c tive tissue slows
down,
with the
control samples,
for example- by ten daysl
.
V.
'
.
r
lr* ^"e restitutedTphase
a- hew epithelial-cbve'rXng-bf-the
of-one—month-after—the—transplantation—the—organa—
'-**•»»
*•* s* C
O
>* a ^ 4 a
^ 1
•
*”
•
4. ^ U. 1
^ .
uc.uxra-.o f the x a n ia fpd
t raasplant,'
jc_e_es_t.abli.sh e s
*
»
' r
*
degree: as
transplants not subjected, to
the activity
.
;
;
-'- f ‘ r.j^atic polarized red light do
in
a period, of
.. 2-3 months
.
-
*
^ r
lycogenes “in the "epiderm
-^
~
’
-
t
d ay«h-flex24—hrs-i-)—an—increase^in—concentration^
.
;
B ; Z
r~^7 1 Srra-4ecrease^-° f 9lycageue—concentxatle>n_ln_£b.e
* *
. »* *"
u
-
T
f
J> ?
:^5 “re-SS—takes place, when compared, with control
' *
-2. 1*-—
hy the more greatly accelerated tempos
— —
—
r
-«•
-’iv change, reflects
the
enlire. regenerative—process-
* i
t
‘
'
~nce ~Of~aUt&—tranapia-FV^»--h--L(-'n
Tn
j-h*»
In ^gya
_
.
n ’
tne
concentrat i nh nf
bwtc
in
the radiated sample
Approved For-Retease-aQQOmZQ?
: ClX^P96-00787R^
,
—