dataesr/scientific-paragraphs-categorization huggingface dataset:
Conclusion: The review of the Google Scholar database revealed that screening of frailty syndrome is not unified and at least 7 different scales are widely used to detect frailty in different settings and countries. Many studies have demonstrated the utility of certain assessment tools to evaluate frailty in populations, however the individual risk for disability has not been properly evaluated, which is the main interest in the FRAILTOOLS project. This abstract is part of the project "662887 / FRAILTOOLS" which has received funding from European Union's Health Programme (2014-2020).
Family interview, the frailty questionnaire ''fragile-VGI index'' is applied, asking the patient's previous status (1 month before the current event), recording the data obtained in an Excel database. Results: We included 274 patients, 149 at the LTCU (58. 18%) and 125 (41. 81%) al CU. In the LTCU the average frailty index was severe (0. 56) and at the CU was mild fragility (0. 26). The diagnosis of dementia and/or delirium is the most related with moderate frailty. Trauma patients obtained mild frailty. Conclusions: AT the LTCU the sever frailty is more common, related to more elderly patients. The mild frailty index confirms the objective of enhancing autonomy and a need of personalized medicine. Planning a one-year follow-up in order to establish association between frailty index and mortality/number of hospital admissions.
Statistically analysis was performed using the SPSS statistical analysis software. Results: Participants were between 60 to 102 years old with a mean age of 77. 4 years (SD = 8. 7 years). According to the global PSQI scores, the figure of 75% of the participants were found to have sleep problems (95% CI of 69-81%) with equal male to female distribution, in comparison to 27. 6% of the participants who reported subjective sleep problems. Decreased activity and poor performance on memory tests were the only demographic and life style variables that had statistical association with sleep problems (OR 2. 85, 95%. Alzheimer disease and schizophrenia were the only medical conditions that had statistical association with sleep problems. Alzheimer disease had a positive association (OR 2. 28, 95% CI 1.
Mortality data at 12 months postdischarge were obtained from hospital records. Non-adherence was determined using a modified version of a validated questionnaire  [3]. Adverse drug reactions were assessed using the Naranjo algorithm  [4]. Adjusted logistic regression models were used to investigate the relationship between ( 2) were included. Sedentary behavior in total (p = 0. 003) and in bouts of more than 30 (p = 0. 006) and 60 min (p = 0. 013) was associated with a higher HbA1c in patients with diabetes mellitus, after adjusting for age, BMI and anti-diabetic drugs. The effect was comparable to the effect of oral antidiabetic medications. We found a negative relationship between blood pressure and sedentary behavior.
Method: A systematic literature search was performed using PubMed, CINAHL, EMBASE and the Cochrane Central Register of Controlled Trials and different search engines and reference lists were scanned for additional studies. Only English and German articles between 2005 and 2015 were included, which focus on people over 65 years and who were living at home during the trial. Two independent reviewers critically assessed the risk of bias in the included studies by using the ''risk of bias tool'' from the Cochrane Collaboration. If the interventions and diagnostic instruments were similar, the data were pooled in a meta-analysis. Results: A total of 18 studies were identified for inclusion in this review. In 14 studies, the fear of falling of community-dwelling elderly was significantly prevented or reduced by the following interventions: seven exercise trainings, one education program and six multicomponent interventions.
Materials and methods: This is a prospective observational study conducted in persons aged 30 or more years, randomly selected from the database of GPs with a comprehensive evaluation including fracture risk, fracture history, diseases, drugs, functional status and lifestyle. Results: 1356 participants, mainly women (n = 756, 55%) with 63% (n = 847) of them aged more than 50 years. Low BMD was detected in 10% (n = 139) and history of fragility fractures in 9% (n = 109). Major clinical risk factors were female gender, family history, gait disorders and falls. Disease-causing bone disorders were detected in 5% (n = 7) and 9% (n = 10), drug affecting bone metabolism in 9% (n = 13) and 9% (n = 10) of persons with low BMD and previous fragility fractures. 56% (n = 62) persons with previous fragility fractures missed the diagnosis of low bone strength.
P-588 Cardiovascular outcomes of cholinesterase inhibitors in patients with dementia: A meta-analysis and systematic review Introduction: To evaluate the cardiovascular effects of acetylcholinesterase inhibitors (AChEIs) in patients with dementia. Methods: Two authors independently searched major electronic databases from inception until 06/17/2017 for longitudinal (without a control group) and cohort (with a control group) studies reporting cardiovascular (CV) outcomes in relation to AChEIs. Randomized controlled trials were excluded due to the inclusion of relatively healthy subjects. Changes in CV parameters were summarized through standardized mean differences (SMD) with 95% confidence intervals (CI). Event rate was used to assess the incidence of hypertension and bradycardia. The incidence of CV events vs.
P-593 Likelihood of institutionalization for demented patients: a lineal or a collateral story? (Study from the French National Alzheimer database) Huvent-Grelle Dominique   and 4. 68  [3. 67-5. 92]  for respectively children and grandchildren and 8. 76  [7. 15-10. 70 ] and 8. 93  [7. 48-10. 65]  for respectively sibling, and niece-nephew.
Method: A literature search for all available papers published from inception until 31st May 2018 was conducted using the scholarly databases. Bibliographies of all included studies were also screened for any related studies. The titles and abstract were screened and the studies that met the inclusion and exclusion criteria were thoroughly reviewed. Relevant data were extracted and summarised to produce clinically relevant inferences. Bias was assessed using the Quality in Prognosis Studies (QUIPS) tool. Results: Fifteen papers were included in the final review. The data was reviewed in a narrative fashion as it was not possible to do a S234 Eur Geriatr Med (2018) 9 (Suppl 1):S1-S367 meta-analysis with the data obtained. CSIs were grouped according to their properties of differentiating between (1) VaD and normal cognition, (2) MCI and normal cognition, and (3) VCI and AD.
NMS-FCM Keyword: Prevention in vulnerable population. Introduction: Data suggest that older adults with dementia are commonly prescribed potentially unsafe medications. Deprescribing refers to supervised tapering or cessation of drugs, aiming to minimize inappropriate polypharmacy and improve patient outcomes. This study reviews the literature about deprescribing in advanced dementia, its benefits, safety and barriers. Material and methods: Non-systematic review of literature using PubMed database using the following keywords: ''advanced dementia'', ''deprescribing'' and ''discontinuing medication''. Results: Most research on potentially inappropriate prescribing is focused on the elderly in general rather than dementia specifically. However, studies are increasingly focusing on prescribing for people with advanced dementia.
Conditional logistic regression was used for data analysis. Results: The dataset contained 28,671 controls and 7259 cases. An increased risk of developing pneumonia was observed to be associated with dysphagia (odds ratios (OR) 3. 57, 95% confidence interval (CI) Aspects of life experiences, such as education, occupational characteristics, or social activities have been linked with a reduced risk of dementia, potentially due to enhancing cognitive reserve. In this study, we collected four reserve-enhancing factors observed over the life course -education (early adulthood), substantive work complexity (midlife), size of the social network, and leisure activities (both late life) and considered their contribution to a latent indicator of cognitive reserve in a Structural Equation Modelling approach.
Dementia risk reduction was similar in both carriers and non-carriers of APOE-e4 allele with high cognitive reserve (HR: 0. 26 and 0. 24, respectively; p \ 0. 01 for both). Not only is cognitive reserve protective of dementia, but it appears to override the detrimental effects of genetic risk. patients that surrogate decision-making for loved ones is becoming more common, especially for dementia. However, it was unclear about how to prepare and support when family member from caregiver turn to surrogate decision maker for people with dementia. Method: An integrative review design was used based on Whittemore and Knafl's study  [1]. A review of English and Japanese language publications before 2018 March was conducted. Searched electronic databases included MEDLINE, CINANL, EmBase, PubMed and ICHUSHI, CiNii.
SPSS 18. 0 and MedCalc programs were used for statistical analyses. Results: A total of 321 patients (133 with normal cognition, 88 aMCI, 100 AD) were included. Median (min-max) age was 75 (60-98) years. One-quarter (25. 1%) had completed high school and above, 65% primary school or lower education levels. Half (51. 1%) of the patients were aged 75 years old and over. The Qmci-TR was statistically significantly better than the MoCA in distinguishing between aMCI and AD in the whole sample and for those attaining high school or higher levels of education (AUC 0. 833; 0. 759 p = 0. 004 and AUC 0. 918; 0. 752 p = 0. 04, respectively). In addition, the Qmci-TR and MMSE were superior to the MoCA in discriminating normal cognition from cognitive impairment in the whole sample and in individuals over 75 years of age.
P-638 Evaluation of postural stability with clinical and laboratory tests in Alzheimer's disease patients Hatice Caliskan Balance Scale and Timed Up&Go Test were performed to all participants. Fall history in previous year and blood tests results in the previous month were recorded. Walk across (WA), sit to stand (STS), tandem walk (TW) and step quick turn (SQT) tests were applied to all participants using computerized posturography, NeuroCom Balance Master (2011). SPSS 21. 0 programme was used for statistical analysis. Results: Mean age was 76±5 vs. 73±4 years in AD and control groups, respectively. Twenty two of the AD patients and 12 of the controls were female. The walking speeds in WA and TW tests were slower in AD patients than the controls (p = 0. 005 and \ 0. 001). WA-step width increased (p = 0.
Caregivers' burden subjective evaluation through Zarit also improved after the intervention. The remaining variables studied, including disease stage, showed association with the scores obtained. Conclusions: our findings suggest that intervention which includes clinical interventions in patients with dementia at the same time as a caregiver education program can improve both the management of the behavioral disorder and the degree of overload of the caregiver. In this way improving the quality of life of the patient and caregiver can improve quality of life. Methods: This is a monocentric, descriptive, retrospective study. We used the ''Banque Nationale de Alzheimer'' (BNA) database to obtain the sociodemographic description of LBD patients. Throughout the medicals records, the clinical data: age, sex, hallucinations, parkinsonian syndrome, symptoms' fluctuation, falls, behavior disturbances and treatments were collected.
The follow-up of the same medical events was obtained from General Practitioner (GP) and Nursing Home physicians through telephone survey. Results: The GPs responded for 67 LBD patients out of 88 found in the BNA database. Mean age was 78. 1 years (SD 7. 4 years) [60; 91], 53% were males. Mean MMSE score was 17/30 at the onset of diagnosis. Diagnostic delay between first symptoms and diagnosis was 734 days and there was no correlation between this delay and patients' age or MMSE score. Symptoms that lead the patient to the Memory Clinic were: cognitive disorders (26. 5%), hallucinations (13. 3%) and parkinsonian syndrome (13. 3%). At the baseline in whole population there was a negative correlation between positive DATSCAN imaging and neuroleptics administration (p \ 0. 001). The comparison of two groups: alive at the time of the phone survey and deceased was done.
65, 95% CI 0. 6-0. 68). Our findings are consistent with those from a small number of studies that provided data on EOD frequency in the general population. Previous work shows that the underestimation of dementia frequency using administrative databases is likely to be less important for EOD. Based on these figures, we extrapolate that there were about 37,000 cases of EOD in France in 2016, including 9000 incident cases.
We define the number of patients that need to be identified and the number of eligible patients that need to be invited in order to achieve the desired recruitment number. Results: Of 1122 patients identified in a database as meeting inclusion criteria only 770 could be invited to participate in the trial. The rest had to be excluded or could not be reached for a variety of reasons despite considerable efforts made by our team of researchers. 420 of the invited patients agreed to participate with younger patients being more inclined to consent. Key conclusions: When planning a RCT involving this cohort of patients one can anticipate that less than 70% of patients identified as meeting inclusion criteria can be invited. We have also established that of those that can be invited the consent rate for such a trial is 54% and it varies slightly with age.
Information was gathered from elderly attending many health care and elderly facilities in Dubai, UAE. People who lived in the UAE and were 65 years old or above were included whilst those who were only visiting the UAE were not included. Overall, the total elderly population in Dubai is estimated to be 32,000 people. With a margin of error of 5% and a confidence level of 90%, the recommended sample size turned out to be 269 people. The sample size included in the study consisted of 300 individuals. The interRAI organization's community health assessment instrument (interRAI CHA) was used as a tool for gathering information. After filling in all the questionnaires, the data was entered into the SPSS Statistics program for analysis. The results obtained delineated which diseases need our support and improved prevention or management.
P-821 'Geriatric 8 Screening Tool' (G8) in cancer patients: an evidence map Gabriel Torbahn 1 , Thomas Strauß 1 , Cornel C Sieber 1 , Dorothee Volkert 1 , Eva Kiesswetter 1   1   Institute for Biomedicine of Aging, Friedrich-Alexander-Universita ¨t Erlangen-Nu ¨rnberg, Erlangen, Germany Introduction: The G8 screening tool was developed to identify older cancer patients who could benefit from comprehensive geriatric assessment (CGA). Our aim was to provide a systematic overview of the characteristics and results of primary studies using the G8 in cancer patients. Methods: A systematic literature search was conducted in 4 databases and 3 study registries. Based on inclusion criteria (primary study with cancer patients, use of G8), titles/abstracts and full-texts were screened and data was extracted by 2 reviewers independently.
Methods: A literature database search was performed electronically via MEDLINE for papers from 2004 until 2018 combining the terms ''fracture liaison service'' with ''hip fracture'' and ''osteoporosis'' including patients aged C 50 years. Results: Twenty three studies were included. Most of them were community studies and very heterogenic in number (including 400 to 151. 00 patients). They categorized by type of fracture, type of antiosteoporotic treatment, re-fractures or economic matters. Ten studies included antiosteoporotic treatment. Most of them described a nonspecific bone health treatment before the fracture with a range between 7 to 20% of patients. The main fracture included was HF. Other fractures were wrist or spine. Three studies showed less risk of second fractures, three reported less mortality rates, and four were cost-effective programs.
Methods: A scoping review was performed; research strategies were generated based on predefined inclusion and exclusion criteria, followed by a systematic database search. Title, abstract and full text screening  (3. 809/77)   Westendorp, & Saczynski, 2014; Siddiqi, House, & Holmes, 2006; Vida et al. , 2006). The purpose of this study was to develop an evidence-based practice guideline for delirium management in hospitalized older patients. Method: A multidisciplinary task group at a medical center in southern Taiwan was established. Team members reviewed current delirium practice guidelines. An adapted practice guideline was developed by constructing foreground questions of key issues, systematical search, appraisal and synthesizing evidences. After a new draft of guidelines was established, the Delphi method was used to reach consensus among expert.
P-854 Calf circumference as a correlate of delirium in hospitalized older people: data from the Italian delirium day 2017 Introduction: So far, there are no studies that assessed the relationship between calf circumference (CC), a marker of sarcopenia and perhaps of frailty in older people, and delirium. This study aims at exploring this potential association in a sample of older people acutely admitted to medical hospital wards. Methods: The ''Italian Delirium Day'' is a multicenter study which is hold yearly in Italy to evaluate the delirium point-prevalence among older patients (C 65 years) admitted to hospital wards and long-term cares facilities. Delirium is assessed on an index day according to 4AT score. Other variables are collected by the attending physician at each center, including demographics, comorbidity, functional status and drugs.
CC is measured as the maximum horizontal distance around the left calf as the subject stood upright. Here we report data from the only medical units. Results: Overall, among those who had full data (817), 191 (23. 4%) patients had delirium. Delirious patients were older (median 87 vs 83 yrs, p \ 0. 001), more disabled (median NMS 2 vs 6, \ 0. 001) and demented (59. 2% vs 10. 9%, p \ 0. 001) than counterpart. The median CC was 29 cm in delirious vs 31 cm in non-delirious, \ 0. 001). In a logistic regression model adjusted for covariates, CC was independent predictor of delirium (Odd Ratio (OR) 0. 96, 95% confidence intervals (CI) 0. 92-0. 99), along with age (OR 1. 03, 95% CI 1. 00-1. 06) and dementia  (OR 10. 49,. Conclusions: CC is a correlate of delirium in acutely hospitalized older patients.
P-855 Visiting policy and delirium prevalence in older inpatients. Data from the delirium day 2016 Background and objectives: Extended visiting time (VT) was suggested as a protective factor for delirium in intensive care units, but its role in general acute hospital is still unclear. We performed an exploratory analysis on the association between VT and delirium in a national multi-centre point prevalence study. Methods: A total of 2609 patients [ 65 years admitted to Medicine, Surgery, Geriatrics, Neurology and post-acute Rehabilitation wards during the Italian Delirium Day 2016 were included in the present analysis. Disability, history of dementia, multimorbidity (Charlson Comorbidity Index) and nutritional status were assessed. Delirium was defined with the 4-AT. Daily VT allowed in each ward was recorded.
Databases searched included Science direct, Scopus, Pub Med, Web of Science and Near East University Grand Library. P-92 Results: 113 patients were included, with a mean age of 81. 9 ± 4. 65 years, and a female predominance (53. 1%). At presen- Barriers of mechanical prophylaxis for deep vein thrombosis tation, 91. 2% were independent of basic activities of daily living, among elderly with hip fracture 92% were continent and 2. 7% were permanent residents in a care Khalid Al-Mugheed 1 , Nurhan Bayraktar 1 home. The most common indication for laparotomy (46%) was bowel obstruction, as a consequence of cancer or adhesions. Following 1 Near East University Faculty of Nursing, Mersin, Turkey surgery, 95(84. 1%) were admitted to the high-dependency unit (HDU). 88(77. 9%) patients survived to discharge.
Aim: to describe the factors that influence long-term mortality after a fragility hip fracture (FHF). Methods: 3-years retrospective study (January 2015 and February 2017) 1-year follow-up. Patients aged [ 65 years admitted with surgical management of FHF were included. Baseline characteristics (Age, sex, comorbidity, previous radiotherapy (RT)), functional status (Barthel Index (BI), Lawton Index (LI), Functional Ambulation Classification (FAC)), cognitive impairment, and in-hospital complications. Multivariate logistic regression analysis and 3 logistic regression model (BI, LI, FAC) has been performed respectively. Statistical significance p \ 0. 005. SPSS 23. 0. Results: 680 patients were included; C 90 years 30. 1%, women 20. 6%. 53. 5% BI [ 80. Severe cognitive impairment 6. 3%. 4. 4% death before discharge.
Statistical analysis: Chi square, Mann-Whitney U, T-Student, SPSS 25. 0. Eur Geriatr Med (2018) 9 (Suppl 1):S1-S367 S81 of the vaccination schedule and digital tools, immunization practice revealed higher rates of non-vaccination with PCV13 in the LEP P-112 remains inadequate. The main objective of the study was to assess group vs English speakers (62% vs. 77% OR 2. 07 95% CI 1. 61, 2. 66 general practitioners (GPs) opinions and practices regarding older p-value \ 0. 0001). Results were similar for PPSV23 (60% vs. 75% Real-world effectiveness of live zoster vaccine: a systematic populations. OR 1. 97 95% CI 1. 54, 2. 51 p-value \ 0. 0001). review Method: This study sought to identify the views of a sample of 250 GPs contacted through a local mailing list. A self-administered questionnaire was assessing socio-demographic characteristics of Discussion: Results: 213 patients were included (46.
The impact of the HIV/AIDS elderly population on the health-care system needs greater recognition and study. P-110 Impact of the adjuvanted recombinant zoster vaccine on pain and use of pain medication in adults aged ‡ 50 years Robert Johnson on behalf of the ZOE-50/70 Study Group 1 1 University of Bristol, Faculty of Health Sciences, Bristol, UK Introduction: To determine the efficacy of a adjuvanted Recombinant Zoster Vaccine (RZV) in reducing the burden of illness (BOI, i. e. pain severity*duration*incidence) and use of pain-related medication in herpes zoster (HZ) episodes. Methods: The assessments were integrated in two Phase III trials, ZOE-50 (subjects C 50 years of age [YOA], NCT01165177) and ZOE-70 (subjects C 70 YOA, NCT01165229). Pain was assessed by the Zoster Brief Pain Inventory (ZBPI) instrument.
05), 54% and 9% of younger patients were pre-frail and frail, respectively. Exhaustion (37%), low physical activity (35%) and weakness (35%) were the most frequent overall criteria (and for those aged \ 65), whereas among older patients, weakness was the most determinant criterion (62% vs. 21%, p \ 0. 001). NYHA classification was not associated with age. Conclusions: As expected, frailty in HF patients is associated with older age and more severe NYHA class. Nevertheless, a considerable proportion of younger patients are frail/pre-frail and this syndrome shows different profiles between ages. Acknowledgements: Supported by ERDF through POCI-01-0145-FEDER-007746, funded by COMPETE2020, National Funds through FCT, within CINTESIS (UID/IC/4255/2013), and Project ''NORTE-01-0145-FEDER-000026-Symbiotic technology for societal efficiency gains: Deus ex Machina'', financed by NORTE2020 under PORTUGAL2020.