dataesr/scientific-paragraphs-categorization huggingface dataset:
O22 Traditional Chinese medicine health education on improving subhealth status: a systematic review Ning Liang, Xue Feng, Jian-ping Liu, Hui-juan Cao Beijing University of Chinese Medicine, Center for Evidence-based Chinese Medicine, Beijing, China Correspondence: Jian-ping Liu (jianping_l@hotmail. com) BMC Complementary and Alternative Medicine 2017, 17(Suppl 1):O22 Question Sub-health status is an intermediate state between health and disease, and could restore to health if handled well with relative risk factors (e. g. excessive pressure, unbalanced diet). This article was to summarize the current delivery ways of traditional Chinese medicine (TCM) health education for sub-health status, and to explore the correlation between TCM health education and sub-health status. Methods Six electronic databases were searched from inception till 2016 August.
Results Databank cleansing of all time points was finalized in December 2016. Currently, the data of the primary and secondary outcomes are being examined. Data are analyzed with linear mixed models including intervention/control group, the interaction of treatment and time, fatigue/HRQOL baseline scores, and the strata center and stage of cancer as fixed effects. The models will also consider a random intercept to take account of the correlation between observations of the same patients assuming an unstructured correlation structure. Complete results of these analyses can be presented in May 2017 at the ECIM&ICCMR.
Conclusions Motivating clinicians to seek out and use the latest evidence to inform patient treatment requires an understanding of the barriers. Some of these have been shown to be practical, like lack of time or access to relevant databases and full text articles, but there is also evidence that significant cultural issues should be considered. The aim of this study was to evaluate the effects of a teaching program that introduces reflexology as an integrative modality in university nursing education. Methods A descriptive observational study was carried out, in which 85 students participated. The students responded by initiating and completing the teaching program, the health questionnaire (SF12v2) and the emotional intelligence questionnaire (TMMS24). The perceived effects during and between sessions were collected on a records grid and their vivid experience were also collected by personal stories.
Challenges include integration of T&CM into universal health coverage (UHC) and primary health care (PHC), lack of research, communication, and reliable information for consumers. The integrative medicine community is a key stakeholder in this strategy. Actions recommended for stakeholders include: establishing best practice; recommending research priorities; advising on risks and benefit; promoting a culture of communication, evaluation, education and innovation; increasing the availability of literature, database and other knowledge resources; developing research methods consistent with T&CM concepts; building research capacity and promoting international collaboration including protection of intellectual property. WHO has developed ICD-11 codes for oriental TM diagnoses. It is reviewing the safety of T&CM practices, starting with acupuncture.
Conclusions The WHO TM strategy is an important opportunity to encourage official and funding bodies to support integration in UHC and PHC and research. We should emphasise our strengths including effective, safe, popular, economical, eco-friendly treatments which harness natural healing; continue to strengthen the knowledge base; promote communication; develop and disseminate effective models of integration in UHC and PHC. Establishing accessible databases to inform evidence-based policy on integration particularly in middle and low income countries is a high priority.
Clinical symptoms and additional biomarkers of cobalamin low status were assessed. Intestinal dysbiosis was also tested by the KyberKompaktPRO test. Review of the literature included the European Food Safety Authoritys position document on reference values for cobalamin. PubMed database was also reviewed (September 2016). Key words included cobalamin, holotranscobalamin, vitamin b12, dysbiosis and Smallintestinal-bacterial-overgrowth.
P14 Therapeutic sensations show high similarity between different body-oriented therapies Florian Beissner Somatosensory and Autonomic Therapy Research, Hannover Medical School, Hannover, 30625, Germany BMC Complementary and Alternative Medicine 2017, 17(Suppl 1):P14 Question Complex bodily sensations that patients experience during therapeutic interventions are a common phenomenon in many bodyoriented therapies. Despite the striking similarity of sensations across different therapy systems, no attempt has been made so far to understand their characteristics and clinical relevance from a perspective that transcends the borders between these systems. Methods We searched the pubmed database for the terms therapeutic sensation, deqi, needling sensation, enhanced touch sensation, acupuncture sensation, propagated sensation, and alternative spellings thereof.
Practitioner Research and Collaboration Initiative: establishment and baseline data for the world's largest practicebased research network in complementary healthcare Amie Steel 1 , Jon Adams 1 , David Sibbritt 1 , Jon Wardle 1 , Matthew Leach 1 , Those interested in joining PRACI were asked to provide contact details to link their results to a PRACI ID number. This data was used to form the foundation of the PRACI membership database. PBRN which affords the potential to support diverse research projects due to its innovative sub-study design. As a result, PRACI offers significant opportunity to facilitate economies of scale and growth in CM research across a broad range of research areas.
1, Nico Steckhan 1 , Thomas Ostermann 2 , Arion Paetow 3 , Evelyn Hoff 3 , Andreas Michalsen1Purpose This systematic review aimed to evaluate the clinical effectiveness and safety of A. paniculata for symptoms of acute RTIs. Methods Nine databases were searched from their inceptions to March 2016 for randomised controlled trials (RCTs) evaluating oral A. Paniculata without language barriers. The primary outcomes were improvement in RTI symptoms and adverse reactions. Random effects model was used to poolthe standardised mean differences and risk ratio to incorporate heterogeneity with 95% CI reported. Methodological quality was evaluated using the Cochrane risk of bias; 2 reviewers independently screened eligibility and extracted data. ResultsThirty-three RCTs (7175 patients) were included.
Practitioner Research and Collaboration Initiative: establishment and baseline data for the world's largest practicebased research network in complementary healthcare Amie Steel 1 , Jon Adams 1 , David Sibbritt 1 , Jon Wardle 1 , Matthew Leach 1 , Those interested in joining PRACI were asked to provide contact details to link their results to a PRACI ID number. This data was used to form the foundation of the PRACI membership database. PBRN which affords the potential to support diverse research projects due to its innovative sub-study design. As a result, PRACI offers significant opportunity to facilitate economies of scale and growth in CM research across a broad range of research areas. Results 764 CM practitioners joined PRACI with the highest number of practi- tioners reporting qualifications in massage therapy (n = 447; 58.
This network meta-analyses (NMA) was conducted to evaluate comparative effectiveness of various acupuncture and related therapies. Methods Eight electronic databases were searched for SRs focusing on randomized controlled trials (RCTs) which investigated acupuncture and related therapies among IBS patients. Data from RCTs were extracted for pair-wise meta-analyses. NMA was used to explore the most effective treatment option. The quality of evidence was assessed using the Cochrane risk of bias tool and the GRADE recommendations. Results Twenty-four RCTs on 2,166 women were included. Compared to no therapy, moderate quality evidence for short-term effects of yoga was found for health-related quality of life (SMD = 0. 22; 95%CI = 0. 04,0. 40; I 2 = 19%), fatigue (SMD = -0. 48; 95%CI = -0. 75,-0.
cramer@kliniken-essen-mitte. de)BMCComplementary and Alternative Medicine 2017, 17(Suppl 1):O9 Question What are the effects of yoga on health-related quality of life, mental health, and cancer-related symptoms in women diagnosed with breast cancer?Methods This abstract is based on a draft and pre-peer review version of a Cochrane Review. Upon completion and approval, the final version is expected to be published in the Cochrane Database of Systematic Reviews (www. cochranelibrary. com). The Cochrane Breast Cancer Group Specialised Register, MEDLINE, EMBASE, IndMED, and CENTRAL were searched through February 2016 for randomized controlled trials (RCTs) assessing the effects of yoga on health-related quality of life, depression, anxiety, fatigue, or sleep disturbances in women diagnosed with breast cancer.
Conclusions NS appeared to improve asthma symptoms, and some asthma- related biomarkers. Future studies should follow patients for a longer period and be a multicentre. Trial Registration: The trial was registered with clinicaltrials. gov, iden- tifier NCT02407262. Keywords: Herbal medicines, clinical trial, RCT, Asthma, Nigella sativa, Black seed O20 Research in integrative pediatrics at a University Children's Hospital in Munich, Germany Sigrid Kruse, Isabell Fischer, Nadine Tremel, Joseph Rosenecker Dr. von Hauner's Children's University Hospital Munich, Department for Integrative and Rehabilitative Pediatrics, Munich, Germany Correspondence: Sigrid Kruse (sigrid. kruse@med. uni-muenchen. de) BMC Complementary and Alternative Medicine 2017, 17(Suppl 1):O20 Material and methodsA chemically characterised NS oil product (Marnys®) marketed as a food supplement was used in a randomised, double-blind, placebocontrolled, phase II trial (RDBPCT) with asthma patients.
Further Boulanger 4 outcomes will be presented at the conference. Trial Registration: ClinicalTrials. gov identifier NCT01864707 O27 Osteopathic treatment in addition to medical standard therapy in patients with Gastroesophageal Reflux Disease (GERD): a randomized controlled trial Michaela Rütz 1 , Andreas Lynen 2 , Meike Schömitz 2 , Maik Vahle 2 1 German Academy of Osteopathy, Gauting, 82131, Germany; 2 Still Conclusion Multicomponent interventions are able to stabilize and even improve Introduction Academy, Mühlheim, Germany dementia symptoms. The growing body of work in this field needs Adverse event (AE) reporting is lacking in massage research. Many to be systematically assessed and evaluated. case reports exist describing medical intervention for purported mas- sage related AEs. The current study provides a rich description re- garding reporting thoroughness and implications of case reports O26 documenting treatment for massage attributed AEs.
pathy, compassion, and pro-social behaviors. Methods A literature search was conducted in PubMed, MEDLINE, PsycINFO, CINAHL, Embase, and Cochrane databases from inception through April 2016 using the search terms: mind-body therapies, mindfulness, meditation, tai chi, yoga, MBSR, MBCT, empathy, compassion, love, altruism, sympathy, or kindness. Randomized controlled trials in any population were included. Cohen"s d = 0. 66). The results at 12 months (n = 61) showed, that the MAKS group remained stable in cognitive function (AMD = -7. 7, 95% CI -14. 0 to -1. 4, P <. 05, Cohen"s d = 0. 45) and ADLs (AMD = 3. 6, 95% CI 0. 7 to 6. 4, P <. 05, Cohen"s d = 0. 50), whereas the control group showed a significant deterioration. The literature review showed that the most common components are varieties of physical and cognitive stimulation.
Data for all colorectal cancer patients are presented in this report. This study was observational, under real practice conditions, with only the available clinical data being collected; there were no additional visits or procedures associated with participation. The decision regarding the chemotherapy treatment administered to patients included in this study was taken prior to enrollment and was not linked to patient participation. Patients participating in other studies that necessitated blinding of treatment were excluded from participating in this study. Each patient was to be followed for six months following enrollment. All patients provided written informed consent at enrollment.
Data Collection Steering committee members in each participating country were invited and selected after an initial phase of study documentation provision and review of study policies and procedures. Steering committee members then selected appropriate physicians in their respective countries, who were trained for participation in the study. These physicians enrolled patients meeting eligibility criteria in consecutive fashion to minimize selection bias. For quality control, a screening log was also maintained for documentation of reasons for nonenrollment of patients. For each enrolled patient, all data were collected using an electronic case report form (eCRF) that was created a priori by the study team. Baseline data collected at the inclusion visit comprised demographics, medical history, cancer diagnosis details, cancer treatment history (including surgery, chemotherapy and biologic therapies, radiation therapy), bleeding and thrombosis history, concomitant medication use history, and laboratory testing results (complete blood count, serum chemistry, coagulation profile).
Data were collected at two-, four-, and six-month visits after the inclusion visit. These included subsequent cancer treatment details, bleeding and thromboembolic episodes, laboratory testing results, concomitant medications, and cancer progression and survival data. Specific investigations to detect occult or asymptomatic venous thrombosis were not performed prospectively at these visits. Such investigations were performed as indicated based on clinical symptoms or physical signs suggestive of VTE. All data were those values available at a date as close as possible to the corresponding study visit. Automatic requests were generated by the eCRF, in case of inconsistencies, to the physician, who was obliged to respond by confirming or modifying the data questioned. Data quality control was planned to be performed on site in 10% of active sites chosen at random in each country or if specific issues were recognized at some sites.
Population Of the 2198 patients triaged to pPCI in the EUROMAX trial, 2104 (95. 7%) received an oral P2Y 12 inhibitor loading dose (90. 9% received the loading dose before angiography). Clopidogrel was used for loading in 1069 patients, prasugrel in 629 patients and ticagrelor in 406 Interventional cardiology patients. P2Y 12 inhibitor maintenance therapy after the procedure was used in 1927 patients (87. 7%). Eight of these received ticlopidine and were excluded, leaving a population of 1919 patients. Figure  1  details the numbers of patients with data who received loading and maintenance doses for each drug.
limitations These data were derived from a prespecified analysis of postrandomisation data. Thus, the decision to use clopidogrel or one of the newer P2Y 12 inhibitors was left to the discretion of the investigators and confounding cannot be excluded. In addition, there were major differences in the geographical distribution and the baseline clinical characteristics as a function of the agent used, some of which can affect the risk of ischaemic or bleeding complications. Even if we performed multivariable adjustments, our results may be partially due to residual confounding. The low number of events and the large CI observed in the comparison of stent thrombosis between the two groups makes a statistical type 2 error possible. This result should therefore be interpreted with caution. The fact that most patients received pretreatment with P2Y 12 inhibitors might have attenuated differences in platelet inhibition between the two groups.
However, precise information on the timing of the administration of the loading dose is not available. The relatively low numbers of patients receiving each of the two newer P2Y 12 agents and low number of stent thromboses prevent a sound comparison between prasugrel and ticagrelor. This comparison is currently being done in a randomised trial (ISAR-REACT 5 trial NCT01944800). Finally, EUROMAX was an open-label trial. However, a central adjudication committee blinded to treatment allocation reviewed all events.
Study design European-pain-audit-in-neonates (EUROPAIN) was a prospective observational study of clinical practices related to sedation/analgesia and was designed using STROBE guidelines  (26). The website (www. europainsurvey. eu) stored multilingual study materials, instructive videos on completing online questionnaires, documents, progress reports and the complete study protocol (http://www. europainsurvey. eu/europain-survey-protocol/). Website links connected authorised users to secure servers (hosted by Voozanoo â ; Epiconcept, Paris, France) for data entry into standardised questionnaires. Participating centres NICU nurses or physicians volunteered as National Principal Investigators (NPIs); each NPI invited participation of all NICUs in their country and provided data on national pain guidelines for neonates.
Level III NICUs initiating and performing the full period of mechanical ventilation were eligible for participation; NICUs unable to provide the full range of Level III care were not eligible. A study nurse, data quality manager and physician coordinator were appointed for each unit, providing information on NICU characteristics and local sedation/analgesia protocols. NICUs were queried about the presence of nurses or physicians with specialised knowledge and/or commitment to neonatal pain management; these clinicians were labelled as physician or nurse pain champions.
Data collection During prespecified enrolment periods, all NICU admissions up to 44 weeks postconceptual age were included. Demographic data, modes of ventilation, use of continuous or intermittent sedation/analgesia or neuromuscular blockers, and assessments of continuous pain for each neonate were collected prospectively during the first 28 days of NICU admission, or until death, or hospital discharge. NICUs were specifically asked to record pain assessments performed with pain tools designed for measuring prolonged, continuous pain; two examples of these scales were given on the data collection sheets [e. g. Echelle Douleur Inconfort Nouveau-n e (EDIN) scale, COMFORT scale] and NICU staff could record any other pain scales they used for continuous pain. Data collection occurred for one month in all participating NICUs; enrolment periods were staggered such that less than forty  (40)  NICUs enrolled patients concomitantly, allowing the coordinating centre to closely monitor data collection at each site.
Subject recruitment was authenticated via the NICU admissions logbook. As the study focus was continuous pain (not procedural pain), we specifically collected data on pain assessments carried out with continuous pain tools, recorded which assessment tools were used, and the number of assessments per day. Newborns were included in the pain-assessed group if at least one assessment of continuous pain occurred during their entire NICU stay. NICUs were included in the pain-assessed group if any assessments of continuous pain were recorded from that unit.
Regulatory compliance Study protocols and data collection were first approved by the regulatory bodies for Protection of Human Subjects, Data Protection, and Health Research Data Management in France and then approved by similar committees in each country and at some participating sites. Information sheets were given to parents to explain the de-identified data collection, and they were free to decline their child's participation. In some countries (e. g. Norway), parents were required to give consent for participation. The study was registered at ClinicalTrials. gov (#NCT01694745).
Data analyses Data analyses used SPSS â v17 (Chicago, IL, USA) for descriptive and multivariable analyses. We used a generalised estimating equation (GEE) multivariable model  (28)  with country or site as the clustering unit. In all neonates, and separately, in ventilated neonates, the clinical factors correlated with NICU pain assessments (p ≤ 0. 05) were included in GEE models. The GEE model fit was assessed by the quasi-likelihood under the independence model criterion (QIC)  (29). Results of GEE models are presented as point-estimate odds ratios (OR) with two-sided 95% confidence intervals (C. I. ). To assess associations between pain assessments and use of opioids, sedative hypnotics or general anaesthetics (O-SH-GA), we analysed data from patient-days with or without O-SH-GA using Mantel-Haenszel chi-square tests, where modes of ventilation (TrV, NiV) by day were the strata.
Study population From October 1, 2012, to June 30, 2013, we enrolled 6648 neonates eligible for this study (Fig. 1 ). Highest levels of ventilation during the study period classified patients into tracheal ventilation (TrV, n = 2138), noninvasive ventilation (NiV, n = 1493) and spontaneous ventilation groups (NoV, n = 3017); patient characteristics are listed in Table  1  and their distribution among participating countries is listed in Table  S1  (Supporting Information). Guidelines for neonatal pain management were available from six countries (33%) and locally, from 182 NICUs (75%). The mean (S. D. ) period of study participation was 11. 9 (9. 7) calendar days. Using data from 78 740 patient-days of observation, units reported continuous pain assessment in 2838 neonates. Further detailed analyses showed that 725 neonates had pain assessed only using procedural pain tools and were thus excluded from this analysis.
We used GEE methods for multivariable analyses to incorporate binary and continuous data, weighted and nonweighted observations, as well as more complex interactions between the variables in our database  (32). NICUs with local pain management guidelines, nursing champions, and increased surgical admissions performed assessments of continuous pain more frequently. Pain assessments also occurred more frequently among newborns <32 weeks gestational age, those requiring surgery, mechanical ventilation, use of opioids (morphine, fentanyl, sufentanil), sedatives-hypnotics (midazolam, lorazepam, barbiturates) or general anaesthetics (ketamine, propofol) in the NICU. Assessments of continuous pain in ventilated neonates were more likely on the patient-days associated with use of opioids, sedatives/hypnotics or general anaesthetics (Fig.
2 ). Even among newborns receiving continuous infusions of O-SH-GA drugs, however, only 48% had assessments of continuous pain on the same day or the day after starting these drugs. To limit the data collection burden on participating NICUs, the timing of pain assessments or drug administration was not recorded; therefore, our data do not permit more detailed analyses of the relationships between pain assessments and therapeutic decision-making. Another limitation could be that participating NICUs do not represent national practices in each country. Because of differences in the number of participating NICUs (and subjects) across the different countries (Table  S1 ), we performed sensitivity analyses to weight the pain assessment results with the proportion of neonates enrolled per 10 000 live births in each country.