dataesr/scientific-paragraphs-categorization huggingface dataset:
,QWHURSHUDELOLW\ DQG FRQQHFWLRQ WR H[WHUQDO GDWD Developed for concession-holders generating hydraulic electricity, the ALOHA tool is fully inter-operable with all business databases. These connections provide access from ALOHA to certain external information, for example: x Maintenance management base; x Operational management database; x Production data; x Hydrometry data; x Estate data managed by other applications. Moreover, the tool allows any type of flow of mapping data from local GIS or external open-data to be integrated.
Based on often shared needs, sometimes very specific to their structures and organisation, the two businesses were able to define a detailed functional specification. Responding to a call for tenders, the company, Advitam-group, provided a solution based on its ScanPrint IMS® package. As it did not offer all the desired functionalities, the Advitam-group developed innovative specific modules: x specific mobile tool and functionalities x concept of readings allowing measurements, components and observations to be attached to an examination device; x concept of scenarios for validations and production of reports The functionalities available in ALOHA V1 at the end of 2015 cover 95% of the needs described by the users at the start of the project and offer possibilities not initially planned. Feedback is positive overall while awaiting a version 2 of the tool in 2016 in order to cover 100% of the business functionalities.
Results: The system was evaluated on multivendor CT datasets of 10 patients presenting from early stage to locally advanced NSCLC or pulmonary metastases. OARs taken into consideration in this study were: heart, lungs, oesophagus, proximal bronchus tree, spinal canal and trachea. Interactive contours were generated by a physician using the proposed system. Delineation of the OARs obtained with the presented system was approved to be usable for RTP in more than 90% of the cases, excluding the oesophagus, which segmentation was never approved (Fig  1 ). On the accepted reported cases, more than 90% of the interactive contours reached a Dice Similarity Coefficient higher than 0. 7 with respect to manual segmentations (Fig  2 ). Therefore, our interactive delineation approach allows users to generate contours of sufficient quality to be used in RTP up to three times faster than manually.
Conclusion: An interactive, accurate and easy-to-use computer-assisted system for OARs segmentation in thoracic oncology was presented and clinically evaluated. The introduction of the proposed approach in clinical routine might offer a valuable new option to radiation therapists (RTTs) in performing OARs delineation task. Consequently, further experiments will be carried out on larger databases and with the participation of additional RTTs to investigate its potential use in daily clinical practice. Material and Methods: ATLAAS, an Automatic decision-Tree based Learning Algorithm for Advanced Segmentation was developed and validated in previous work. ATLAAS (patent pending PCT/GB2015/052981) is a predictive segmentation model, trained with machine learning to automatically select and apply the best PET-AS method, according to the tumour characteristics.
PO-0933 Towards standardisation of PET auto-segmentation with the ATLAAS machine learning algorithm B. Berthon Results: ATLAAS contours were closer to the true contour for all cases. The DSCs obtained with ATLAAS were 5. 3% to 123% higher across cases than DSCs obtained for RT50 and 4. 1% to 74% higher than for RT42. The largest differences between ATLAAS and relative thresholding were obtained for lung images, the smallest differences for H&N and Brain tumours. The minimum conformity of ATLAAS contours on the whole dataset was 0. 81 DSC compared to 0. 38 and 0. 47 for RT50 and RT42 respectively.
Radiation doses above 250 Gy are usually required to induce complete sterility in male moths (IDIDAS Database;  Bakri et al. 2005) , but these high radiation doses negatively affect their competitiveness  (Carpenter et al. 2005). In most moth species, the females are more radiation-sensitive than the males  (LaChance 1985; Robinson 2005). For this reason and because of the absence of genetic sexing systems for lepidopteran species-although progress in developing such a system has been reported  (Marec et al. 2007 )-, the SIT requires that both genders must be irradiated with a dose sufficiently great to almost fully sterilize the released males. However in order to take advantage of the fact that irradiation of chromosomes with diffuse centromeres with somewhat reduced doses leads to dominant lethal chromosomal aberrations in subsequent generations, a derivative of the SIT-called F 1 sterility or inherited sterility (IS)-was developed for lepidopteran pests  (Proverbs 1962; North 1975; LaChance 1985; Carpenter et al.
Modeling A conceptual model was developed that was based on 2 basic spatial elements of AW-IPM programs, i. e. , the core area and the buffer area. The model was developed to determine the minimum size of the protected area of an AW-IPM program needed to assure its technical feasibility and economic viability. The model consisted of a biological part (insect dispersal) and an economic part. The biological part used random walks and diffusion equations to describe insect dispersal and to determine the minimum width of the buffer area required to protect the core area from migrating insects. The economic part calculated the minimum size of the core area at which the revenues of the core area would equal the control program costs  (Barclay et al. 2011). Kean et al. (2011)  developed a population model for the light brown apple moth, Epiphyas postvittana (Walker) (Lepidoptera: Tortricidae) that indicated that releasing 300 Gy-irradiated moths will result in a 95% probability of extinction when the ratio of released to wild moths exceeds 6.
2012 ). The second model, a reaction-diffusion model, described the growth of the wild population and the interaction between wild and sterile E. saccharina moths in a temporally variable and spatially heterogeneous environment. The primary objective was to use the model in an AW-IPM program context to investigate the efficiency of different sterile moth release strategies without having to conduct formal field experiments, and to present guidelines according to which release ratios, release frequencies and spatial distributions of releases may be estimated that are expected to lead to suppression of the pest  (Potgieter et al. 2013 ). As a follow-up of the 2 previous models,  Potgieter et al. (2016, this  special issue) developed a user-friendly simulation model for determining the impact of an IS program on E.
; all resulting in substantially increased program costs  (Simmons et al. 2010). Much of the focus on quality control of mass-or laboratory-reared insects necessarily concerns maintenance of facility output (i. e. , numbers produced), but much too little attention and resources have been devoted to in-depth considerations of individual trait effects, e. g. , mating competitiveness, and flight performance and dispersal in the field. Trait performance is becoming acknowledged as an essential factor in integrated pest management success  (Sørensen et al. 2012). Indeed, keen awareness of the importance of quality traits in the success of area-wide IPM programs is growing. Although insect quality management is routinely practiced in many mass-rearing facilities, there is a dearth of in-depth knowledge of the factors and variables that affect the quality and the field performance of released moths.
The system showed potential for the routine quality assessment of mass-reared moths and might be suitable for factory scale quality assurance  (Brown et al. 2016, in this special issue). The suitability of simple flight cylinders to assess differences in various batches of the quality of mass-produced moths was investigated by  Carpenter et al. (2012). Cylinder diam and ht and the duration (h) after the test had been initiated influenced the numbers of male and female moths leaving the cylinder. The data showed that this simple flight cylinder bioassay was adequate in detecting differences in codling moth quality induced by various treatments whose influence could also be detected by more complex laboratory essays and field trials  (Carpenter et al. 2012). Laboratory bioassays (flight ability and mating) and field bioassays (field cage and open field releases) were carried out simultaneously to assess the abilities of these various bioassays to measure or predict quality and field performance of mass-reared codling moths.
Sperm Differences between F 1 and Wild Male Moths During an AW-IPM program that has a SIT/IS component against a lepidopteran pest it is possible that traps used to monitor wild moth populations and to determine over-flooding ratios capture unmarked F 1 sterile males that cannot be distinguished from wild fertile males. A cytological technique based on orcein and Giemsa stains was found to distinguish adult F 1 progeny of irradiated males and fertile males of 6 pest species in 5 families of Lepidoptera. The nuclei cluster in each of the eupyrene sperm bundles in the fertile males showed a regular and organized arrangement of the sperm and was homogeneously stained, whereas the nuclei clusters of sperm bundles of F 1 males were disorganized, irregular and unevenly stained  (Carpenter et al.
However, the standard method of measuring isotope signatures uses elemental analysis-isotope ratio mass-spectrometry (EA-IRMS), which is so costly that it has hindered the advancement and wide spread adoption of this approach. Hood-Nowotny et al. (2016b, in this special issue) took advantage of the development of a simpler technology based on laser spectroscopy that is much cheaper and more convenient than EA-IRMS. Data obtained with combustion module-cavity ring-down spectroscopy (CM-CRDS) were in good agreement with those obtained using EA-IRMS in terms of accuracy and precision.
Bioassays and assessments included moth mass, moth longevity, percentage of female moths mated at time of collection from the insectary, percentage of female moths mated 24 h after collection, flight ability, percentage recapture after release in the field, and mean distance dispersed from the release site. Data from the quality assessments of the 2 insectaries were compared and used to make protocol changes in both rearing and handling that improved sterile moth quality and performance  (Hight & Carpenter 2016 , in this special issue). In several Lepidoptera programs that incorporate the SIT/IS, cold temperature is routinely used to immobilize moths to increase the density of moths to facilitate their collection, holding, irradiation, transport and release  (Bloem et al. 2001). However cold temperatures or rapid chilling and prolonged storage may negatively impact field performance of some insectary-reared insects  (Terblanche et al.
Materials and methods We reviewed data from critically ill cirrhotic patients and matched controls in which routine therapeutic drug monitoring of broad-spectrum β-lactam antibiotics (piperacillin/ tazobactam; meropenem) was performed. Serum drug concentrations were measured twice during the elimination phase by high-performance liquid chromatography. Antibiotic pharmacokinetics was calculated using a one-compartment model. We considered therapy was adequate when serum drug concentrations were between 4 and 8 times the minimal inhibitory concentration of Pseudomonas aeruginosa during optimal periods of time for each drug ≥50 % for piperacillin/tazobactam; ≥40 % for meropenem). Results We studied 38 cirrhotic patients (16 for piperacillin/tazobactam and 22 for meropenem) and 38 matched controls.
Patients and methods We prospectively analyzed patients with septic shock admitted to a general ICU over a 28-month period who presented Doppler signs of left intraventricular obstruction. Clinical characteristics and hemodynamic parameters as well as echocardiographic data regarding left ventricular function, size, and calculated mass, and left ventricular outflow Doppler pattern and velocity before and after fluid infusions were recorded. Results During the study period, 218 patients with septic shock were admitted to our ICU. Hemodynamic and echocardiographic characteristics of patients with intraventricular obstruction before and after fluid infusion are given in Table  2. Left intraventricular obstruction was observed in 47 (22 %) patients. Mortality rate at 28 days was found to be higher in patients with than in patients without left intraventricular obstruction (55 vs 33 %, p < 0.
Patients and methods We studied a monocentric cohort of 41 consecutive CVT in a French tertiary hospital. Data collected were as follows: demographic data, clinical course, incidence of craniectomy and/ or endovascular procedures, outcome in ICU, after 3, and 12 months. Results 1-Characteristics 73. 2 % were female, 47 years old (IQ 26-53), having a SAPS II 41 (32-45), GCS 7  (5) (6) (7) (8) , and at least one episode of mydriasis in 48. 8 %. 48. 8 % had seizures before ICU admission and 43. 9 % during ICU stay.
Patients and methods We used the prospective French multicentric Outcomerea database. Four outcomes were assessed: death, the occurrence of nosocomial infection, ischemic event and acute respiratory distress syndrome. In each analysis, we included patients with sepsis severe and septic shock since 04/01/1998 and excluded patients with hemorrhagic shock on admission. Only patients staying for more than 48 h were analyzed to estimate the risk of nosocomial infection. Similarly, patients having ischemic events during the first 48 h were not included in the estimation of the risk of ischemic event. A marginal structural cox model with ponderation on the inverse probability of treatment weight (IPTW) and inverse probability of censoring weight (IPCW) was then used to estimate the impact of transfusion with a censoring at day 30.
Introduction The thrombotic microangiopathy (TMA) syndrome encompasses a wide spectrum pathologies including thrombotic thrombocytopenic purpura (TTP) and complement-mediated TMA [formerly known as atypical hemolytic uremic syndrome (HUS)]. The aim of the present study was to describe the first clinical symptoms in critically ill TMA patients and to evaluate the impact of pre-intensive care unit (ICU) location on the patients' outcomes. Patients and methods Patients with TMA admitted to a 12-bed medical university hospital ICU between 2009 and 2015 were identified using a computerized database. Data concerning the pre-ICU period and clinico-biological parameters were abstracted from medical charts. Data are expressed as numbers (%) and medians (interquartile range). Comparisons were made using the Chi square test or the Mann-Whitney U test as appropriate.
Regarding the whole ultrasound dataset (TUS model), only lung parameters (A, B1 and B2 profiles) and the echocardiographic estimation of left ventricular filling pressures (E/e) emerged as reliable predictors. Crucially, the predictive value of TUS was significantly greater than CB during both H0 and H1 assessments (Fig. 9 ). Introduction Weaning-induced pulmonary oedema (WIPO) has not been investigated in large series of patients. Although diuretics are widely used to treat it, the dose that must be administered is unknown. Our aim was to describe the incidence of weaning-induced pulmonary oedema (WIPO) in a population of critically ill patients, to compare the characteristics of patients with and without WIPO and to detail the effects of diuretics on WIPO.
Patients and methods We performed a post hoc analysis of the TRIAL OH database. The TRIAL OH study was prospectively carried out in 17 university or university-affiliated centers in France and Belgium  (2010) (2011) (2012). Central neurological failure was defined by any neurological disorder of central origin among impairment of consciousness, seizure with or without status epilepticus, focal neurological signs, encephalopathy, and meningeal symptoms.
Results To validate the diagnostic score, we collected data from an independent dataset of 238 patients with HMS admitted to 26 ICUs for ARF (iVNIctus trial), including 15 (6. 3 %) patients with PjP. When compared to patients with other ARF etiologies, PjP patients were younger (33 aged <50 vs. 20 %, P = 0. 02), had more frequently a lymphoproliferative disorder (93. 3 vs. 45. 7 %, P = 0. 0003), never received prophylaxis (vs. 36 % in other ARF etiologies, P < 0. 0001) and had more frequently an interstitial pattern on chest imaging (67 vs. 32 %). The three other components of the score, namely time since respiratory symptoms onset, shock at admission and pleural involvement, were not significantly different between PjP patients and those with other ARF etiologies. In this reliability cohort, the score has a very good discrimination [AUC was 0.
Results From November 2013 to June 2015, at 11 university sites, 1062 patients were included in this trial. Recruitment has now ended and 780 patients have been kept for final analysis, the remaining being secondary excluded mainly because sepsis was not confirmed by the adjudication committee. At inclusion, 523 (67 %) were hospitalized in the ICU and 257 were from the ED. All the sites have performed the related flow cytometry according to a standardized protocol. The database cleaning process and locking should be done in the coming weeks followed by the statistical analysis. Results will be available in the coming 2 months. Conclusion Septiflux 2 is the larger multicenter trial that has evaluated the prognostic value of immature granulocytes and the overall interest of flow cytometry at the acute phase of sepsis.
Patients and methods We performed a retrospective analysis of a large prospective multicenter cohort database involving 20 French ICUs. Every adult patient with AKI at ICU admission according to the KDIGO definition was included. Renal recovery was defined by a decrease in one stage or more according to the KDIGO classification. Results are reported as medians (interquartile range, IQR) or numbers (%). Variable of interest was day-28 mortality, and influence of renal recovery was assessed after adjustment in a cause-specific hazard model taking time dependency of this variable into account. Discharge alive from the ICU was used as a competing event. Results Overall, of 18,684 patients of our database, 5229 had an AKI at ICU admission and were included in this study. 3167 patients were of male gender (60.
Patients and methods We performed a retrospective analysis from a prospective, multicenter, regional scientific database (Traumabase ® ), of all patients admitted to the Beaujon University Hospital ICU between January 2011 and December 2013. Only patients for whom a troponin assay was performed on arrival were included for analysis (immunological methods of chemiluminescence-ARCHITECT STAT Troponin-I ® , positivity threshold 0. 05 ng/ml). If more than one value were available, the highest troponin value over the first 24 h was retained for analysis. The primary endpoint was the cTn-I elevation and the ICU mortality. Continuous variable is expressed as median and interquartile range and categorical variables as absolute value and relative frequencies. Univariable and multivariable logistic regression analysis was performed for cTn-I elevation and ICU mortality.
Patients and methods All trauma obese and non-obese patients admitted in a Level I Regional Trauma Center were included. Were excluded patients who died immediately after admission or not directly admitted or with important clinical data missing in the database. MT rate and TASH score were assessed in obese [body mass index (BMI) ≥30 kg/m 2 ] and non-obese (BMI <30 kg/m 2 ) patients. Logistic regression was performed to assess the relationship between obesity and MT, before and after adjusting for ISS score. The odds ratio (OR) was provided for obesity status and for an increase of 5 units of BMI with the 95 % confidence interval (CI). Received operating characteristic (ROC) curve analysis was performed for the TASH score in predicting MT in the obese and non-obese groups. Thereafter, thresholds analysis was carried out from the ROC curves using the grey zone method.
Conclusion Eclampsia is still a major cause of maternal morbidity and mortality worldwide. It incidence remains high, especially for developing countries in need of health care. Several studies are needed to determine all the risk factors and improve maternal prognosis. Introduction Severe sepsis and septic shock are a frequent lifethreatening cause of ICU admission of cirrhotic patients. Among the antibiotics frequently used in intensive care, the prescription of aminoglycosides to cirrhotic patients is controversial because of their nephrotoxicity. The aim of this study was to evaluate the use of aminoglycosides administration among cirrhotic patients admitted in intensive care unit for severe sepsis and septic shock and study their impact on mortality and renal function. Patients and methods Cirrhotic patients with severe sepsis and septic shock were selected over a 18-year period (1997-2014) from a longitudinal prospective French multicenter database.
For each article, residents were randomly assigned to one of the three following versions: (1) full version of the article; (2) incomplete version, without discussion; and (3) flash version, restricted to abstract, tables and figures. The evaluation of the understanding of the article was evaluated by a senior physician according to a standardized grid, assessing six main points: (1) objectives, (2) study population, (3) design, (4) main outcomes, (5) main bias and (6) external validity. Residents were asked to give the main message of the study. All articles were then discussed with the senior intensivists during a journal club session. One month later, residents were asked to recall the main message of each article. Data are presented as percentages or median (interquartile range). Results Twenty residents evaluated 25 different articles (randomized controlled studies n = 16, cohorts n = 7).
The aim of our study was to describe the incidence and risks factors for DI in our ICU. Patients and methods We conducted a monocentric, prospective observational study between January 2014 and May 2015. All patients admitted to our ICU and requiring intubation were included in the study. Exclusion criteria comprised age under 18 and refusal from the patients or their relatives to participate. An intubation procedure was defined as difficult whenever it required more than two laryngoscopic attempts by a senior intensivist or the use of a different technique (stylet, gum bougies, laryngeal masks, fiberoptic intubation, cricothyroidotomy or tracheostomy). Patients' comorbidities, demographic data and classical risk factors for difficult intubation in anesthesiology, as well as the MACOCHA score, were collected on admission.
Materials and methods This systematic review and meta-analysis was performed according to the PRISMA statements. Public domain databases including PubMed and the Cochrane database were searched by using predefined keywords. The research was restricted to articles published in English and studies focusing on critically ill adult patients from May 2005 to May 2015. Results were analyzed using Review Manager 5. 1 software. Overall, mortality is reported as median (IQR). Publication bias was assessed by visually inspecting the funnel plot. Then, summary estimates of risk difference were then calculated using the random-effect model.