Title: Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones
Authors: orcid: https://orcid.org/0000-0001-6030-6173
last_name: Kirstein
first_name: Nina
name: Nina Kirstein
affiliations: label: 1
address: Munich
institution: Research Unit Gene Vectors, Helmholtz Zentrum München (GmbH), German Research Center for Environmental Health
country: Germany
name: Research Unit Gene Vectors, Helmholtz Zentrum München (GmbH), German Research Center for Environmental Health Munich Germany
last_name: Buschle
first_name: Alexander
name: Alexander Buschle
affiliations: label: 2
address: Munich
institution: Research Unit Gene Vectors, Helmholtz Zentrum München (GmbH), German Research Center for Environmental Health and German Center for Infection Research (DZIF)
country: Germany
name: Research Unit Gene Vectors, Helmholtz Zentrum München (GmbH), German Research Center for Environmental Health and German Center for Infection Research (DZIF) Munich Germany
last_name: Wu
first_name: Xia
name: Xia Wu
affiliations: label: 3
address: Paris
institution: Institut de Biologie de l'ENS (IBENS), Département de Biologie, Ecole Normale Supérieure, CNRS, Inserm, PSL Research University
country: France
name: Institut de Biologie de l'ENS (IBENS), Département de Biologie, Ecole Normale Supérieure, CNRS, Inserm, PSL Research University Paris France
last_name: Krebs
first_name: Stefan
name: Stefan Krebs
affiliations: label: 4
address: Munich
institution: Laboratory for Functional Genome Analysis (LAFUGA), Gene Center of the Ludwig-Maximilians Universität (LMU) München
country: Germany
name: Laboratory for Functional Genome Analysis (LAFUGA), Gene Center of the Ludwig-Maximilians Universität (LMU) München Munich Germany
last_name: Blum
first_name: Helmut
name: Helmut Blum
affiliations: label: 4
address: Munich
institution: Laboratory for Functional Genome Analysis (LAFUGA), Gene Center of the Ludwig-Maximilians Universität (LMU) München
country: Germany
name: Laboratory for Functional Genome Analysis (LAFUGA), Gene Center of the Ludwig-Maximilians Universität (LMU) München Munich Germany
last_name: Kremmer
first_name: Elisabeth
name: Elisabeth Kremmer
affiliations: label: 5
address: Neuherberg
institution: Institute for Molecular Immunology, Monoclonal Antibody Core Facility, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH)
country: Germany
name: Institute for Molecular Immunology, Monoclonal Antibody Core Facility, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH) Neuherberg Germany
orcid: http://orcid.org/0000-0003-0583-4015
last_name: Vorberg
first_name: Ina M
name: Ina M Vorberg
affiliations: label: 6
address: Bonn
institution: German Center for Neurodegenerative Diseases (DZNE e.V.)
country: Germany
name: German Center for Neurodegenerative Diseases (DZNE e.V.) Bonn Germany
label: 7
address: Bonn
institution: Rheinische Friedrich-Wilhelms-Universität Bonn
country: Germany
name: Rheinische Friedrich-Wilhelms-Universität Bonn Bonn Germany
orcid: http://orcid.org/0000-0002-4659-0427
last_name: Hammerschmidt
first_name: Wolfgang
name: Wolfgang Hammerschmidt
affiliations: label: 2
address: Munich
institution: Research Unit Gene Vectors, Helmholtz Zentrum München (GmbH), German Research Center for Environmental Health and German Center for Infection Research (DZIF)
country: Germany
name: Research Unit Gene Vectors, Helmholtz Zentrum München (GmbH), German Research Center for Environmental Health and German Center for Infection Research (DZIF) Munich Germany
last_name: Lacroix
first_name: Laurent
name: Laurent Lacroix
affiliations: label: 3
address: Paris
institution: Institut de Biologie de l'ENS (IBENS), Département de Biologie, Ecole Normale Supérieure, CNRS, Inserm, PSL Research University
country: France
name: Institut de Biologie de l'ENS (IBENS), Département de Biologie, Ecole Normale Supérieure, CNRS, Inserm, PSL Research University Paris France
orcid: https://orcid.org/0000-0001-8879-675X
last_name: Hyrien
first_name: Olivier
name: Olivier Hyrien
corresponding: yes
affiliations: label: 3
address: Paris
institution: Institut de Biologie de l'ENS (IBENS), Département de Biologie, Ecole Normale Supérieure, CNRS, Inserm, PSL Research University
country: France
name: Institut de Biologie de l'ENS (IBENS), Département de Biologie, Ecole Normale Supérieure, CNRS, Inserm, PSL Research University Paris France
orcid: https://orcid.org/0000-0003-2683-9990
last_name: Audit
first_name: Benjamin
name: Benjamin Audit
corresponding: yes
affiliations: label: 8
address: 69342 Lyon
institution: Univ Lyon, ENS de Lyon, Univ. Claude Bernard, CNRS, Laboratoire de Physique
country: France
name: Univ Lyon, ENS de Lyon, Univ. Claude Bernard, CNRS, Laboratoire de Physique 69342 Lyon France
orcid: https://orcid.org/0000-0002-5442-5608
last_name: Schepers
first_name: Aloys
name: Aloys Schepers
corresponding: yes
affiliations: label: 1
address: Munich
institution: Research Unit Gene Vectors, Helmholtz Zentrum München (GmbH), German Research Center for Environmental Health
country: Germany
name: Research Unit Gene Vectors, Helmholtz Zentrum München (GmbH), German Research Center for Environmental Health Munich Germany
Affiliations: label: 1
address: Munich
institution: Research Unit Gene Vectors, Helmholtz Zentrum München (GmbH), German Research Center for Environmental Health
country: Germany
name: Research Unit Gene Vectors, Helmholtz Zentrum München (GmbH), German Research Center for Environmental Health Munich Germany
label: 2
address: Munich
institution: Research Unit Gene Vectors, Helmholtz Zentrum München (GmbH), German Research Center for Environmental Health and German Center for Infection Research (DZIF)
country: Germany
name: Research Unit Gene Vectors, Helmholtz Zentrum München (GmbH), German Research Center for Environmental Health and German Center for Infection Research (DZIF) Munich Germany
label: 3
address: Paris
institution: Institut de Biologie de l'ENS (IBENS), Département de Biologie, Ecole Normale Supérieure, CNRS, Inserm, PSL Research University
country: France
name: Institut de Biologie de l'ENS (IBENS), Département de Biologie, Ecole Normale Supérieure, CNRS, Inserm, PSL Research University Paris France
label: 4
address: Munich
institution: Laboratory for Functional Genome Analysis (LAFUGA), Gene Center of the Ludwig-Maximilians Universität (LMU) München
country: Germany
name: Laboratory for Functional Genome Analysis (LAFUGA), Gene Center of the Ludwig-Maximilians Universität (LMU) München Munich Germany
label: 5
address: Neuherberg
institution: Institute for Molecular Immunology, Monoclonal Antibody Core Facility, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH)
country: Germany
name: Institute for Molecular Immunology, Monoclonal Antibody Core Facility, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH) Neuherberg Germany
label: 6
address: Bonn
institution: German Center for Neurodegenerative Diseases (DZNE e.V.)
country: Germany
name: German Center for Neurodegenerative Diseases (DZNE e.V.) Bonn Germany
label: 7
address: Bonn
institution: Rheinische Friedrich-Wilhelms-Universität Bonn
country: Germany
name: Rheinische Friedrich-Wilhelms-Universität Bonn Bonn Germany
label: 8
address: 69342 Lyon
institution: Univ Lyon, ENS de Lyon, Univ. Claude Bernard, CNRS, Laboratoire de Physique
country: France
name: Univ Lyon, ENS de Lyon, Univ. Claude Bernard, CNRS, Laboratoire de Physique 69342 Lyon France
institution: Cold Spring Harbor Laboratory
country: United States
name: Cold Spring Harbor Laboratory United States
institution: Harvard Medical School
country: United States
name: Harvard Medical School United States
institution: Cold Spring Harbor Laboratory
country: United States
name: Cold Spring Harbor Laboratory United States
institution: Cold Spring Harbor Laboratory
country: United States
name: Cold Spring Harbor Laboratory United States
Field: Biochemistry, Genetics and Molecular Biology
Document type: article
Year: 2021