Title: Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy
Authors: orcid: https://orcid.org/0000-0002-2891-2111
last_name: Springer
first_name: Simeon U
name: Simeon U Springer
affiliations: label: 1
address: Baltimore
institution: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics
country: United States
name: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics Baltimore United States
label: 2
address: Baltimore
institution: Sidney Kimmel Comprehensive Cancer Center
country: United States
name: Sidney Kimmel Comprehensive Cancer Center Baltimore United States
last_name: Chen
first_name: Chung-Hsin
name: Chung-Hsin Chen
affiliations: label: 3
address: Taipei
institution: Department of Urology
country: Taiwan
name: Department of Urology National Taiwan University Hospital Taipei Taiwan
orcid: http://orcid.org/0000-0002-3439-7013
last_name: Rodriguez Pena
first_name: Maria Del Carmen
name: Maria Del Carmen Rodriguez Pena
affiliations: label: 4
address: Baltimore
institution: Department of Pathology
country: United States
name: Department of Pathology Johns Hopkins University Baltimore United States
label: 5
address: Birmingham
institution: Department of Pathology
country: United States
name: Department of Pathology University of Alabama at Birmingham Birmingham United States
orcid: https://orcid.org/0000-0002-1920-4965
last_name: Li
first_name: Lu
name: Lu Li
affiliations: label: 6
address: Baltimore
institution: Department of Biostatistics
country: United States
name: Department of Biostatistics Johns Hopkins Bloomberg School of Public Health Baltimore United States
orcid: http://orcid.org/0000-0002-2510-4151
last_name: Douville
first_name: Christopher
name: Christopher Douville
affiliations: label: 7
address: Baltimore
institution: Department of Biomedical Engineering, Institute for Computational Medicine
country: United States
name: Department of Biomedical Engineering, Institute for Computational Medicine Johns Hopkins University Baltimore United States
orcid: https://orcid.org/0000-0002-2932-6042
last_name: Wang
first_name: Yuxuan
name: Yuxuan Wang
affiliations: label: 1
address: Baltimore
institution: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics
country: United States
name: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics Baltimore United States
label: 2
address: Baltimore
institution: Sidney Kimmel Comprehensive Cancer Center
country: United States
name: Sidney Kimmel Comprehensive Cancer Center Baltimore United States
orcid: http://orcid.org/0000-0003-1158-5668
last_name: Cohen
first_name: Joshua David
name: Joshua David Cohen
affiliations: label: 1
address: Baltimore
institution: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics
country: United States
name: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics Baltimore United States
label: 2
address: Baltimore
institution: Sidney Kimmel Comprehensive Cancer Center
country: United States
name: Sidney Kimmel Comprehensive Cancer Center Baltimore United States
last_name: Taheri
first_name: Diana
name: Diana Taheri
affiliations: label: 4
address: Baltimore
institution: Department of Pathology
country: United States
name: Department of Pathology Johns Hopkins University Baltimore United States
label: 8
address: Isfahan
institution: Department of Pathology, Isfahan Kidney Diseases Research Center
country: Iran
name: Department of Pathology, Isfahan Kidney Diseases Research Center Isfahan University of Medical Sciences Isfahan Iran
last_name: Silliman
first_name: Natalie
name: Natalie Silliman
affiliations: label: 1
address: Baltimore
institution: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics
country: United States
name: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics Baltimore United States
label: 2
address: Baltimore
institution: Sidney Kimmel Comprehensive Cancer Center
country: United States
name: Sidney Kimmel Comprehensive Cancer Center Baltimore United States
last_name: Schaefer
first_name: Joy
name: Joy Schaefer
affiliations: label: 1
address: Baltimore
institution: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics
country: United States
name: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics Baltimore United States
label: 2
address: Baltimore
institution: Sidney Kimmel Comprehensive Cancer Center
country: United States
name: Sidney Kimmel Comprehensive Cancer Center Baltimore United States
last_name: Ptak
first_name: Janine
name: Janine Ptak
affiliations: label: 1
address: Baltimore
institution: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics
country: United States
name: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics Baltimore United States
label: 2
address: Baltimore
institution: Sidney Kimmel Comprehensive Cancer Center
country: United States
name: Sidney Kimmel Comprehensive Cancer Center Baltimore United States
last_name: Dobbyn
first_name: Lisa
name: Lisa Dobbyn
affiliations: label: 1
address: Baltimore
institution: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics
country: United States
name: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics Baltimore United States
label: 2
address: Baltimore
institution: Sidney Kimmel Comprehensive Cancer Center
country: United States
name: Sidney Kimmel Comprehensive Cancer Center Baltimore United States
last_name: Papoli
first_name: Maria
name: Maria Papoli
affiliations: label: 1
address: Baltimore
institution: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics
country: United States
name: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics Baltimore United States
label: 2
address: Baltimore
institution: Sidney Kimmel Comprehensive Cancer Center
country: United States
name: Sidney Kimmel Comprehensive Cancer Center Baltimore United States
last_name: Kinde
first_name: Isaac
name: Isaac Kinde
affiliations: label: 1
address: Baltimore
institution: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics
country: United States
name: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics Baltimore United States
label: 2
address: Baltimore
institution: Sidney Kimmel Comprehensive Cancer Center
country: United States
name: Sidney Kimmel Comprehensive Cancer Center Baltimore United States
last_name: Afsari
first_name: Bahman
name: Bahman Afsari
affiliations: label: 9
address: Baltimore
institution: Department of Oncology
country: United States
name: Department of Oncology Johns Hopkins University Baltimore United States
label: 10
address: Baltimore
institution: Division of Biostatistics and Bioinformatics, Department of Oncology, Sidney Kimmel Cancer Center
country: United States
name: 10 Division of Biostatistics and Bioinformatics, Department of Oncology, Sidney Kimmel Cancer Center Johns Hopkins School of Medicine Baltimore United States
last_name: Tregnago
first_name: Aline C
name: Aline C Tregnago
affiliations: label: 4
address: Baltimore
institution: Department of Pathology
country: United States
name: Department of Pathology Johns Hopkins University Baltimore United States
last_name: Bezerra
first_name: Stephania M
name: Stephania M Bezerra
affiliations: label: 11
address: Sao Paulo
institution: Department of Pathology
country: Brazil
name: 11 Department of Pathology AC Camargo Cancer Center Sao Paulo Brazil
last_name: VandenBussche
first_name: Christopher
name: Christopher VandenBussche
affiliations: label: 4
address: Baltimore
institution: Department of Pathology
country: United States
name: Department of Pathology Johns Hopkins University Baltimore United States
last_name: Fujita
first_name: Kazutoshi
name: Kazutoshi Fujita
affiliations: label: 12
address: Osaka
institution: Department of Pathology
country: Japan
name: 12 Department of Pathology Osaka University Osaka Japan
last_name: Ertoy
first_name: Dilek
name: Dilek Ertoy
affiliations: label: 13
address: Ankara
institution: Department of Pathology
country: Turkey
name: 13 Department of Pathology Hacettepe University Ankara Turkey
last_name: Cunha
first_name: Isabela W
name: Isabela W Cunha
affiliations: label: 11
address: Sao Paulo
institution: Department of Pathology
country: Brazil
name: 11 Department of Pathology AC Camargo Cancer Center Sao Paulo Brazil
orcid: https://orcid.org/0000-0001-6735-9569
last_name: Yu
first_name: Lijia
name: Lijia Yu
affiliations: label: 5
address: Birmingham
institution: Department of Pathology
country: United States
name: Department of Pathology University of Alabama at Birmingham Birmingham United States
last_name: Bivalacqua
first_name: Trinity J
name: Trinity J Bivalacqua
affiliations: label: 14
address: Baltimore
institution: Department of Urology
country: United States
name: 14 Department of Urology Johns Hopkins University Baltimore United States
last_name: Grollman
first_name: Arthur P
name: Arthur P Grollman
affiliations: label: 15
address: Stony Brook
institution: Department of Pharmacological Sciences
country: United States
name: 15 Department of Pharmacological Sciences Stony Brook University Stony Brook United States
label: 16
address: Stony Brook
institution: Department of Medicine
country: United States
name: 16 Department of Medicine Stony Brook University Stony Brook United States
last_name: Diaz
first_name: Luis A
name: Luis A Diaz
affiliations: label: 17
address: New York
institution: Department of Medicine
country: United States
name: 17 Department of Medicine Memorial Sloan Kettering Cancer Center New York United States
last_name: Karchin
first_name: Rachel
name: Rachel Karchin
affiliations: label: 7
address: Baltimore
institution: Department of Biomedical Engineering, Institute for Computational Medicine
country: United States
name: Department of Biomedical Engineering, Institute for Computational Medicine Johns Hopkins University Baltimore United States
label: 9
address: Baltimore
institution: Department of Oncology
country: United States
name: Department of Oncology Johns Hopkins University Baltimore United States
last_name: Danilova
first_name: Ludmila
name: Ludmila Danilova
affiliations: label: 10
address: Baltimore
institution: Division of Biostatistics and Bioinformatics, Department of Oncology, Sidney Kimmel Cancer Center
country: United States
name: 10 Division of Biostatistics and Bioinformatics, Department of Oncology, Sidney Kimmel Cancer Center Johns Hopkins School of Medicine Baltimore United States
label: 13
address: Ankara
institution: Department of Pathology
country: Turkey
name: 13 Department of Pathology Hacettepe University Ankara Turkey
last_name: Huang
first_name: Chao-Yuan
name: Chao-Yuan Huang
affiliations: label: 3
address: Taipei
institution: Department of Urology
country: Taiwan
name: Department of Urology National Taiwan University Hospital Taipei Taiwan
last_name: Shun
first_name: Chia-Tung
name: Chia-Tung Shun
affiliations: label: 18
address: Taipei
institution: Department of Forensic Medicine and Pathology
country: Taiwan
name: 18 Department of Forensic Medicine and Pathology National Taiwan University Hospital Taipei Taiwan
last_name: Turesky
first_name: Robert J
name: Robert J Turesky
affiliations: label: 19
address: Minneapolis
institution: Masonic Cancer Center
country: United States
name: 19 Masonic Cancer Center University of Minnesota Minneapolis United States
label: 20
address: Minneapolis
institution: Department of Medicinal Chemistry
country: United States
name: 20 Department of Medicinal Chemistry University of Minnesota Minneapolis United States
last_name: Yun
first_name: Byeong Hwa
name: Byeong Hwa Yun
affiliations: label: 19
address: Minneapolis
institution: Masonic Cancer Center
country: United States
name: 19 Masonic Cancer Center University of Minnesota Minneapolis United States
label: 20
address: Minneapolis
institution: Department of Medicinal Chemistry
country: United States
name: 20 Department of Medicinal Chemistry University of Minnesota Minneapolis United States
last_name: Rosenquist
first_name: Thomas A
name: Thomas A Rosenquist
affiliations: label: 15
address: Stony Brook
institution: Department of Pharmacological Sciences
country: United States
name: 15 Department of Pharmacological Sciences Stony Brook University Stony Brook United States
last_name: Pu
first_name: Yeong-Shiau
name: Yeong-Shiau Pu
affiliations: label: 3
address: Taipei
institution: Department of Urology
country: Taiwan
name: Department of Urology National Taiwan University Hospital Taipei Taiwan
last_name: Hruban
first_name: Ralph H
name: Ralph H Hruban
affiliations: label: 4
address: Baltimore
institution: Department of Pathology
country: United States
name: Department of Pathology Johns Hopkins University Baltimore United States
last_name: Tomasetti
first_name: Cristian
name: Cristian Tomasetti
affiliations: label: 6
address: Baltimore
institution: Department of Biostatistics
country: United States
name: Department of Biostatistics Johns Hopkins Bloomberg School of Public Health Baltimore United States
label: 10
address: Baltimore
institution: Division of Biostatistics and Bioinformatics, Department of Oncology, Sidney Kimmel Cancer Center
country: United States
name: 10 Division of Biostatistics and Bioinformatics, Department of Oncology, Sidney Kimmel Cancer Center Johns Hopkins School of Medicine Baltimore United States
last_name: Papadopoulos
first_name: Nickolas
name: Nickolas Papadopoulos
affiliations: label: 1
address: Baltimore
institution: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics
country: United States
name: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics Baltimore United States
label: 2
address: Baltimore
institution: Sidney Kimmel Comprehensive Cancer Center
country: United States
name: Sidney Kimmel Comprehensive Cancer Center Baltimore United States
last_name: Kinzler
first_name: Ken W
name: Ken W Kinzler
affiliations: label: 1
address: Baltimore
institution: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics
country: United States
name: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics Baltimore United States
label: 2
address: Baltimore
institution: Sidney Kimmel Comprehensive Cancer Center
country: United States
name: Sidney Kimmel Comprehensive Cancer Center Baltimore United States
orcid: https://orcid.org/0000-0003-0766-3854
last_name: Vogelstein
first_name: Bert
name: Bert Vogelstein
corresponding: yes
affiliations: label: 1
address: Baltimore
institution: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics
country: United States
name: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics Baltimore United States
label: 2
address: Baltimore
institution: Sidney Kimmel Comprehensive Cancer Center
country: United States
name: Sidney Kimmel Comprehensive Cancer Center Baltimore United States
orcid: https://orcid.org/0000-0003-1308-2992
last_name: Dickman
first_name: Kathleen G
name: Kathleen G Dickman
corresponding: yes
affiliations: label: 15
address: Stony Brook
institution: Department of Pharmacological Sciences
country: United States
name: 15 Department of Pharmacological Sciences Stony Brook University Stony Brook United States
label: 16
address: Stony Brook
institution: Department of Medicine
country: United States
name: 16 Department of Medicine Stony Brook University Stony Brook United States
orcid: https://orcid.org/0000-0003-3915-9134
last_name: Netto
first_name: George J
name: George J Netto
corresponding: yes
affiliations: label: 4
address: Baltimore
institution: Department of Pathology
country: United States
name: Department of Pathology Johns Hopkins University Baltimore United States
label: 5
address: Birmingham
institution: Department of Pathology
country: United States
name: Department of Pathology University of Alabama at Birmingham Birmingham United States
Affiliations: label: 1
address: Baltimore
institution: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics
country: United States
name: Howard Hughes Medical Institute, Ludwig Center for Cancer Genetics and Therapeutics Baltimore United States
label: 2
address: Baltimore
institution: Sidney Kimmel Comprehensive Cancer Center
country: United States
name: Sidney Kimmel Comprehensive Cancer Center Baltimore United States
label: 3
address: Taipei
institution: Department of Urology
country: Taiwan
name: Department of Urology National Taiwan University Hospital Taipei Taiwan
label: 4
address: Baltimore
institution: Department of Pathology
country: United States
name: Department of Pathology Johns Hopkins University Baltimore United States
label: 5
address: Birmingham
institution: Department of Pathology
country: United States
name: Department of Pathology University of Alabama at Birmingham Birmingham United States
label: 6
address: Baltimore
institution: Department of Biostatistics
country: United States
name: Department of Biostatistics Johns Hopkins Bloomberg School of Public Health Baltimore United States
label: 7
address: Baltimore
institution: Department of Biomedical Engineering, Institute for Computational Medicine
country: United States
name: Department of Biomedical Engineering, Institute for Computational Medicine Johns Hopkins University Baltimore United States
label: 8
address: Isfahan
institution: Department of Pathology, Isfahan Kidney Diseases Research Center
country: Iran
name: Department of Pathology, Isfahan Kidney Diseases Research Center Isfahan University of Medical Sciences Isfahan Iran
label: 9
address: Baltimore
institution: Department of Oncology
country: United States
name: Department of Oncology Johns Hopkins University Baltimore United States
label: 10
address: Baltimore
institution: Division of Biostatistics and Bioinformatics, Department of Oncology, Sidney Kimmel Cancer Center
country: United States
name: 10 Division of Biostatistics and Bioinformatics, Department of Oncology, Sidney Kimmel Cancer Center Johns Hopkins School of Medicine Baltimore United States
label: 11
address: Sao Paulo
institution: Department of Pathology
country: Brazil
name: 11 Department of Pathology AC Camargo Cancer Center Sao Paulo Brazil
label: 12
address: Osaka
institution: Department of Pathology
country: Japan
name: 12 Department of Pathology Osaka University Osaka Japan
label: 13
address: Ankara
institution: Department of Pathology
country: Turkey
name: 13 Department of Pathology Hacettepe University Ankara Turkey
label: 14
address: Baltimore
institution: Department of Urology
country: United States
name: 14 Department of Urology Johns Hopkins University Baltimore United States
label: 15
address: Stony Brook
institution: Department of Pharmacological Sciences
country: United States
name: 15 Department of Pharmacological Sciences Stony Brook University Stony Brook United States
label: 16
address: Stony Brook
institution: Department of Medicine
country: United States
name: 16 Department of Medicine Stony Brook University Stony Brook United States
label: 17
address: New York
institution: Department of Medicine
country: United States
name: 17 Department of Medicine Memorial Sloan Kettering Cancer Center New York United States
label: 18
address: Taipei
institution: Department of Forensic Medicine and Pathology
country: Taiwan
name: 18 Department of Forensic Medicine and Pathology National Taiwan University Hospital Taipei Taiwan
label: 19
address: Minneapolis
institution: Masonic Cancer Center
country: United States
name: 19 Masonic Cancer Center University of Minnesota Minneapolis United States
label: 20
address: Minneapolis
institution: Department of Medicinal Chemistry
country: United States
name: 20 Department of Medicinal Chemistry University of Minnesota Minneapolis United States
institution: Memorial Sloan Kettering Cancer Center
country: United States
name: Memorial Sloan Kettering Cancer Center United States
institution: Memorial Sloan Kettering Cancer Center
country: United States
name: Memorial Sloan Kettering Cancer Center United States
Field: Medicine
Document type: article
Year: 2018