Title: A Fully-Adjusted Two-Stage Procedure for Rank Normalization in Genetic Association Studies
Authors: last_name: Sofer
first_name: Tamar
name: Tamar Sofer
corresponding: yes
affiliations: label: 1
institution: Department of Medicine, Harvard Medical School
country: USA
name: Department of Medicine, Harvard Medical School , Boston, MA, USA
label: 2
institution: Dividsion of Sleep and Circadian Disorders, Brigham and Women’s Hospital
country: USA
name: Dividsion of Sleep and Circadian Disorders, Brigham and Women’s Hospital , Boston, MA, USA
last_name: Zheng
first_name: Xiuwen
name: Xiuwen Zheng
affiliations: label: 3
institution: Department of Biostatistics, University of Washington
country: USA
name: Department of Biostatistics, University of Washington , Seattle, WA, USA
last_name: Gogarten
first_name: Stephanie M.
name: Stephanie M. Gogarten
affiliations: label: 3
institution: Department of Biostatistics, University of Washington
country: USA
name: Department of Biostatistics, University of Washington , Seattle, WA, USA
last_name: Laurie
first_name: Cecelia A.
name: Cecelia A. Laurie
affiliations: label: 3
institution: Department of Biostatistics, University of Washington
country: USA
name: Department of Biostatistics, University of Washington , Seattle, WA, USA
last_name: Grinde
first_name: Kelsey
name: Kelsey Grinde
affiliations: label: 3
institution: Department of Biostatistics, University of Washington
country: USA
name: Department of Biostatistics, University of Washington , Seattle, WA, USA
last_name: Shaffer
first_name: John R.
name: John R. Shaffer
affiliations: label: 4
institution: Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh
country: USA
name: Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh , Pittsburgh, PA, USA
label: 5
institution: Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh
country: USA
name: Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh , Pittsburgh, PA, USA
last_name: Shungin
first_name: Dmitry
name: Dmitry Shungin
affiliations: label: 6
institution: Broad Institute of Harvard and MIT
country: USA
name: Broad Institute of Harvard and MIT , Cambridge, MA, USA
label: 7
institution: Department of Odontology, Umeå University
country: Sweden
name: Department of Odontology, Umeå University , Umeå, Sweden
last_name: O’Connell
first_name: Jeffrey R.
name: Jeffrey R. O’Connell
affiliations: label: 8
institution: Department of Medicine, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine
country: USA
name: Department of Medicine, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine , Baltimore, MD, USA
last_name: Durazo-Arvizo
first_name: Ramon A.
name: Ramon A. Durazo-Arvizo
affiliations: label: 9
institution: Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago
country: USA
name: Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago , Maywood, USA
last_name: Raffield
first_name: Laura
name: Laura Raffield
affiliations: label: 10
institution: Department of Genetics, University of North Carolina
country: USA
name: 10 Department of Genetics, University of North Carolina , Chapel Hill, NC, USA
last_name: Lange
first_name: Leslie
name: Leslie Lange
affiliations: label: 11
institution: Department of Medicine, University of Colorado Denver, Anschutz Medical Campus
country: USA
name: 11 Department of Medicine, University of Colorado Denver, Anschutz Medical Campus , Aurora, CO, USA
last_name: Musani
first_name: Solomon
name: Solomon Musani
affiliations: label: 12
institution: Department of Medicine, University of Mississippi Medical Center
country: USA
name: 12 Department of Medicine, University of Mississippi Medical Center , Jackson, MS, USA
last_name: Vasan
first_name: Ramachandran S.
name: Ramachandran S. Vasan
affiliations: label: 13
institution: Departments of Medicine, Biostatistics and Epidemiology, Boston University Schools of Medicine and Public Health
country: USA
name: 13 Departments of Medicine, Biostatistics and Epidemiology, Boston University Schools of Medicine and Public Health , Boston, MA, USA
label: 14
institution: Boston University’s and National Heart, Lung, and Blood Institute’s Framingham Heart Study
country: USA
name: 14 Boston University’s and National Heart, Lung, and Blood Institute’s Framingham Heart Study , Framingham, MA, USA
last_name: Adrienne Cupples
first_name: L.
name: L. Adrienne Cupples
affiliations: label: 15
institution: Department of Biostatistics, Boston University School of Public Health
country: USA
name: 15 Department of Biostatistics, Boston University School of Public Health , Boston, MA, USA
last_name: Reiner
first_name: Alexander P.
name: Alexander P. Reiner
affiliations: label: 16
institution: Department of Epidemiology, School of Public Health, University of Washington
country: USA
name: 16 Department of Epidemiology, School of Public Health, University of Washington , Seattle, WA, USA
last_name: Laurie
first_name: Cathy C.
name: Cathy C. Laurie
affiliations: label: 3
institution: Department of Biostatistics, University of Washington
country: USA
name: Department of Biostatistics, University of Washington , Seattle, WA, USA
last_name: Rice
first_name: Kenneth M.
name: Kenneth M. Rice
affiliations: label: 3
institution: Department of Biostatistics, University of Washington
country: USA
name: Department of Biostatistics, University of Washington , Seattle, WA, USA
Affiliations: label: 1
institution: Department of Medicine, Harvard Medical School
country: USA
name: Department of Medicine, Harvard Medical School , Boston, MA, USA
label: 2
institution: Dividsion of Sleep and Circadian Disorders, Brigham and Women’s Hospital
country: USA
name: Dividsion of Sleep and Circadian Disorders, Brigham and Women’s Hospital , Boston, MA, USA
label: 3
institution: Department of Biostatistics, University of Washington
country: USA
name: Department of Biostatistics, University of Washington , Seattle, WA, USA
label: 4
institution: Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh
country: USA
name: Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh , Pittsburgh, PA, USA
label: 5
institution: Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh
country: USA
name: Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh , Pittsburgh, PA, USA
label: 6
institution: Broad Institute of Harvard and MIT
country: USA
name: Broad Institute of Harvard and MIT , Cambridge, MA, USA
label: 7
institution: Department of Odontology, Umeå University
country: Sweden
name: Department of Odontology, Umeå University , Umeå, Sweden
label: 8
institution: Department of Medicine, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine
country: USA
name: Department of Medicine, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine , Baltimore, MD, USA
label: 9
institution: Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago
country: USA
name: Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago , Maywood, USA
label: 10
institution: Department of Genetics, University of North Carolina
country: USA
name: 10 Department of Genetics, University of North Carolina , Chapel Hill, NC, USA
label: 11
institution: Department of Medicine, University of Colorado Denver, Anschutz Medical Campus
country: USA
name: 11 Department of Medicine, University of Colorado Denver, Anschutz Medical Campus , Aurora, CO, USA
label: 12
institution: Department of Medicine, University of Mississippi Medical Center
country: USA
name: 12 Department of Medicine, University of Mississippi Medical Center , Jackson, MS, USA
label: 13
institution: Departments of Medicine, Biostatistics and Epidemiology, Boston University Schools of Medicine and Public Health
country: USA
name: 13 Departments of Medicine, Biostatistics and Epidemiology, Boston University Schools of Medicine and Public Health , Boston, MA, USA
label: 14
institution: Boston University’s and National Heart, Lung, and Blood Institute’s Framingham Heart Study
country: USA
name: 14 Boston University’s and National Heart, Lung, and Blood Institute’s Framingham Heart Study , Framingham, MA, USA
label: 15
institution: Department of Biostatistics, Boston University School of Public Health
country: USA
name: 15 Department of Biostatistics, Boston University School of Public Health , Boston, MA, USA
label: 16
institution: Department of Epidemiology, School of Public Health, University of Washington
country: USA
name: 16 Department of Epidemiology, School of Public Health, University of Washington , Seattle, WA, USA
Field: Biochemistry, Genetics and Molecular Biology
Document type: preprint
Year: 2018