Title: Rescue of Conformational Dynamics in Enzyme Catalysis by Directed Evolution
Authors: last_name: Otten
first_name: Renee
name: Renee Otten
affiliations: label: 1
institution: Howard Hughes Medical Institute and Department of Biochemistry, Brandeis University
country: USA
name: Howard Hughes Medical Institute and Department of Biochemistry, Brandeis University , 415 South Street, Waltham, MA 02454, USA
notes: Present address: Biological Sciences West, The University of Arizona, 1041 E Lowell Street, Tucson, AZ 85721, USA
last_name: Liu
first_name: Lin
name: Lin Liu
affiliations: label: 2
institution: Department of Bioengineering and Therapeutic Sciences, University of California San Francisco
country: USA
name: Department of Bioengineering and Therapeutic Sciences, University of California San Francisco , San Francisco, CA 94158, USA
notes: Present address: Biological Sciences West, The University of Arizona, 1041 E Lowell Street, Tucson, AZ 85721, USA
last_name: Kenner
first_name: Lillian R.
name: Lillian R. Kenner
affiliations: label: 2
institution: Department of Bioengineering and Therapeutic Sciences, University of California San Francisco
country: USA
name: Department of Bioengineering and Therapeutic Sciences, University of California San Francisco , San Francisco, CA 94158, USA
last_name: Clarkson
first_name: Michael W.
name: Michael W. Clarkson
affiliations: label: 1
institution: Howard Hughes Medical Institute and Department of Biochemistry, Brandeis University
country: USA
name: Howard Hughes Medical Institute and Department of Biochemistry, Brandeis University , 415 South Street, Waltham, MA 02454, USA
notes: Present address: Biological Sciences West, The University of Arizona, 1041 E Lowell Street, Tucson, AZ 85721, USA
last_name: Mavor
first_name: David
name: David Mavor
affiliations: label: 2
institution: Department of Bioengineering and Therapeutic Sciences, University of California San Francisco
country: USA
name: Department of Bioengineering and Therapeutic Sciences, University of California San Francisco , San Francisco, CA 94158, USA
last_name: Tawfik
first_name: Dan S.
name: Dan S. Tawfik
affiliations: label: 3
institution: Department of Biomolecular Sciences, Weizmann Institute of Science
country: Israel
name: Department of Biomolecular Sciences, Weizmann Institute of Science , Rehovot, Israel
last_name: Kern
first_name: Dorothee
name: Dorothee Kern
affiliations: label: 1
institution: Howard Hughes Medical Institute and Department of Biochemistry, Brandeis University
country: USA
name: Howard Hughes Medical Institute and Department of Biochemistry, Brandeis University , 415 South Street, Waltham, MA 02454, USA
last_name: Fraser
first_name: James S.
name: James S. Fraser
affiliations: label: 2
institution: Department of Bioengineering and Therapeutic Sciences, University of California San Francisco
country: USA
name: Department of Bioengineering and Therapeutic Sciences, University of California San Francisco , San Francisco, CA 94158, USA
Affiliations: label: 1
institution: Howard Hughes Medical Institute and Department of Biochemistry, Brandeis University
country: USA
name: Howard Hughes Medical Institute and Department of Biochemistry, Brandeis University , 415 South Street, Waltham, MA 02454, USA
label: 2
institution: Department of Bioengineering and Therapeutic Sciences, University of California San Francisco
country: USA
name: Department of Bioengineering and Therapeutic Sciences, University of California San Francisco , San Francisco, CA 94158, USA
label: 3
institution: Department of Biomolecular Sciences, Weizmann Institute of Science
country: Israel
name: Department of Biomolecular Sciences, Weizmann Institute of Science , Rehovot, Israel
Field: Biochemistry, Genetics and Molecular Biology
Document type: preprint
Year: 2017