Title: Antibiotic resistance evasion is explained by rare mutation frequency and not by lack of compensatory mechanisms
Authors: last_name: Evangelopoulos
first_name: Dimitrios
name: Dimitrios Evangelopoulos
affiliations: label: 1
institution: Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute
country: United Kingdom
name: Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute , 1 Midland Road, London NW1 1AT, United Kingdom
notes: These authors contributed equally to this work.
last_name: Prosser
first_name: Gareth A.
name: Gareth A. Prosser
affiliations: label: 1
institution: Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute
country: United Kingdom
name: Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute , 1 Midland Road, London NW1 1AT, United Kingdom
notes: These authors contributed equally to this work.
Current address: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20850, USA.
last_name: Rodgers
first_name: Angela
name: Angela Rodgers
affiliations: label: 1
institution: Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute
country: United Kingdom
name: Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute , 1 Midland Road, London NW1 1AT, United Kingdom
last_name: Dagg
first_name: Belinda M.
name: Belinda M. Dagg
affiliations: label: 3
institution: Bacteriology Division, National Institute for Biological Standards and Control (MHRA-NIBSC)
country: United Kingdom
name: Bacteriology Division, National Institute for Biological Standards and Control (MHRA-NIBSC) , Blanche Lane, South Mimms, Potters Bar, Herts EN6 3QG, United Kingdom
last_name: Khatri
first_name: Bhagwati
name: Bhagwati Khatri
affiliations: label: 3
institution: Bacteriology Division, National Institute for Biological Standards and Control (MHRA-NIBSC)
country: United Kingdom
name: Bacteriology Division, National Institute for Biological Standards and Control (MHRA-NIBSC) , Blanche Lane, South Mimms, Potters Bar, Herts EN6 3QG, United Kingdom
orcid: http://orcid.org/0000-0003-2875-4552
last_name: Ho
first_name: Mei Mei
name: Mei Mei Ho
affiliations: label: 3
institution: Bacteriology Division, National Institute for Biological Standards and Control (MHRA-NIBSC)
country: United Kingdom
name: Bacteriology Division, National Institute for Biological Standards and Control (MHRA-NIBSC) , Blanche Lane, South Mimms, Potters Bar, Herts EN6 3QG, United Kingdom
last_name: Gutierrez
first_name: Maximiliano G.
name: Maximiliano G. Gutierrez
affiliations: label: 2
institution: Host-Pathogen Interactions in Tuberculosis Laboratory, The Francis Crick Institute
country: United Kingdom
name: Host-Pathogen Interactions in Tuberculosis Laboratory, The Francis Crick Institute , 1 Midland Road, London NW1 1AT, United Kingdom
last_name: Cortes
first_name: Teresa
name: Teresa Cortes
affiliations: label: 4
institution: Department of Pathogen Molecular Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine
country: United Kingdom
name: Department of Pathogen Molecular Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine , London WC1E 7HT, United Kingdom
last_name: de Carvalho
first_name: Luiz Pedro S.
name: Luiz Pedro S. de Carvalho
corresponding: yes
affiliations: label: 1
institution: Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute
country: United Kingdom
name: Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute , 1 Midland Road, London NW1 1AT, United Kingdom
Affiliations: label: 1
institution: Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute
country: United Kingdom
name: Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute , 1 Midland Road, London NW1 1AT, United Kingdom
label: 2
institution: Host-Pathogen Interactions in Tuberculosis Laboratory, The Francis Crick Institute
country: United Kingdom
name: Host-Pathogen Interactions in Tuberculosis Laboratory, The Francis Crick Institute , 1 Midland Road, London NW1 1AT, United Kingdom
label: 3
institution: Bacteriology Division, National Institute for Biological Standards and Control (MHRA-NIBSC)
country: United Kingdom
name: Bacteriology Division, National Institute for Biological Standards and Control (MHRA-NIBSC) , Blanche Lane, South Mimms, Potters Bar, Herts EN6 3QG, United Kingdom
label: 4
institution: Department of Pathogen Molecular Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine
country: United Kingdom
name: Department of Pathogen Molecular Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine , London WC1E 7HT, United Kingdom
Field: Biochemistry, Genetics and Molecular Biology
Document type: preprint
Year: 2018