Title: Functional normalization of 450k methylation array data improves replication in large cancer studies
Authors: last_name: Fortin
first_name: Jean-Philippe
name: Jean-Philippe Fortin
affiliations: label: 1
institution: Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health
name: Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health
last_name: Labbe
first_name: Aurélie
name: Aurélie Labbe
affiliations: label: 2
institution: Department of Epidemiology, Biostatistics and Occupational Health, McGill University
name: Department of Epidemiology, Biostatistics and Occupational Health, McGill University
label: 3
institution: Douglas Mental Health University Institute, McGill University
name: Douglas Mental Health University Institute, McGill University
last_name: Lemire
first_name: Mathieu
name: Mathieu Lemire
affiliations: label: 4
institution: Ontario Institute of Cancer Research
name: Ontario Institute of Cancer Research
last_name: Zanke
first_name: Brent W.
name: Brent W. Zanke
affiliations: label: 5
institution: Clinical Epidemiology Program, Ottawa Hospital Research Institute
name: Clinical Epidemiology Program, Ottawa Hospital Research Institute
orcid: http://orcid.org/0000-0002-1376-4849
last_name: Hudson
first_name: Thomas J.
name: Thomas J. Hudson
affiliations: label: 4
institution: Ontario Institute of Cancer Research
name: Ontario Institute of Cancer Research
label: 6
institution: Departments of Molecular Genetics and Medical Biophysics, University of Toronto
name: Departments of Molecular Genetics and Medical Biophysics, University of Toronto
last_name: Fertig
first_name: Elana J.
name: Elana J. Fertig
affiliations: label: 7
institution: Department of Oncology, Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine
name: Department of Oncology, Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine
last_name: Greenwood
first_name: Celia M.T.
name: Celia M.T. Greenwood
affiliations: label: 2
institution: Department of Epidemiology, Biostatistics and Occupational Health, McGill University
name: Department of Epidemiology, Biostatistics and Occupational Health, McGill University
label: 8
institution: Lady Davis Institute for Medical Research, Jewish General Hospital Montreal
name: Lady Davis Institute for Medical Research, Jewish General Hospital Montreal
label: 9
institution: Department of Oncology, McGill University
name: Department of Oncology, McGill University
orcid: http://orcid.org/0000-0003-0086-0687
last_name: Hansen
first_name: Kasper D.
name: Kasper D. Hansen
corresponding: yes
affiliations: label: 1
institution: Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health
name: Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health
label: 10
institution: McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins School of Medicine
name: 10 McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins School of Medicine
Affiliations: label: 1
institution: Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health
name: Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health
label: 2
institution: Department of Epidemiology, Biostatistics and Occupational Health, McGill University
name: Department of Epidemiology, Biostatistics and Occupational Health, McGill University
label: 3
institution: Douglas Mental Health University Institute, McGill University
name: Douglas Mental Health University Institute, McGill University
label: 4
institution: Ontario Institute of Cancer Research
name: Ontario Institute of Cancer Research
label: 5
institution: Clinical Epidemiology Program, Ottawa Hospital Research Institute
name: Clinical Epidemiology Program, Ottawa Hospital Research Institute
label: 6
institution: Departments of Molecular Genetics and Medical Biophysics, University of Toronto
name: Departments of Molecular Genetics and Medical Biophysics, University of Toronto
label: 7
institution: Department of Oncology, Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine
name: Department of Oncology, Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine
label: 8
institution: Lady Davis Institute for Medical Research, Jewish General Hospital Montreal
name: Lady Davis Institute for Medical Research, Jewish General Hospital Montreal
label: 9
institution: Department of Oncology, McGill University
name: Department of Oncology, McGill University
label: 10
institution: McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins School of Medicine
name: 10 McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins School of Medicine
Field: Biochemistry, Genetics and Molecular Biology
Document type: preprint
Year: 2014