Title: Systems medicine links microbial inflammatory response with glycoprotein-associated mortality risk
Authors: last_name: Ritchie
first_name: Scott C
name: Scott C Ritchie
affiliations: label: 1
institution: Centre for Systems Genomics, School of Biological Sciences, The University of Melbourne
country: Australia
name: Centre for Systems Genomics, School of Biological Sciences, The University of Melbourne , Parkville 3010, Victoria, Australia
label: 2
institution: Department of Pathology, The University of Melbourne
country: Australia
name: Department of Pathology, The University of Melbourne , Parkville 3010, Victoria, Australia
last_name: Würtz
first_name: Peter
name: Peter Würtz
affiliations: label: 3
institution: Computational Medicine, Institute of Health Sciences, University of Oulu
country: Finland
name: Computational Medicine, Institute of Health Sciences, University of Oulu , Oulu, Finland
last_name: Nath
first_name: Artika P
name: Artika P Nath
affiliations: label: 1
institution: Centre for Systems Genomics, School of Biological Sciences, The University of Melbourne
country: Australia
name: Centre for Systems Genomics, School of Biological Sciences, The University of Melbourne , Parkville 3010, Victoria, Australia
label: 2
institution: Department of Pathology, The University of Melbourne
country: Australia
name: Department of Pathology, The University of Melbourne , Parkville 3010, Victoria, Australia
last_name: Abraham
first_name: Gad
name: Gad Abraham
affiliations: label: 1
institution: Centre for Systems Genomics, School of Biological Sciences, The University of Melbourne
country: Australia
name: Centre for Systems Genomics, School of Biological Sciences, The University of Melbourne , Parkville 3010, Victoria, Australia
label: 2
institution: Department of Pathology, The University of Melbourne
country: Australia
name: Department of Pathology, The University of Melbourne , Parkville 3010, Victoria, Australia
last_name: Havulinna
first_name: Aki S
name: Aki S Havulinna
affiliations: label: 4
institution: National Institute for Health and Welfare
country: Finland
name: National Institute for Health and Welfare , Finland
label: 5
institution: Institute for Molecular Medicine Finland, University of Helsinki
country: Finland
name: Institute for Molecular Medicine Finland, University of Helsinki , Helsinki, Finland
last_name: Kangas
first_name: Antti J
name: Antti J Kangas
affiliations: label: 3
institution: Computational Medicine, Institute of Health Sciences, University of Oulu
country: Finland
name: Computational Medicine, Institute of Health Sciences, University of Oulu , Oulu, Finland
last_name: Soininen
first_name: Pasi
name: Pasi Soininen
affiliations: label: 3
institution: Computational Medicine, Institute of Health Sciences, University of Oulu
country: Finland
name: Computational Medicine, Institute of Health Sciences, University of Oulu , Oulu, Finland
label: 6
institution: NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland
country: Finland
name: NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland , Kuopio, Finland
last_name: Aalto
first_name: Kristiina
name: Kristiina Aalto
affiliations: label: 7
institution: MediCity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku
country: Finland
name: MediCity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku , Turku, Finland
last_name: Seppälä
first_name: Ilkka
name: Ilkka Seppälä
affiliations: label: 8
institution: Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, School of Medicine
country: Finland
name: Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, School of Medicine , Tampere, Finland
last_name: Raitoharju
first_name: Emma
name: Emma Raitoharju
affiliations: label: 8
institution: Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, School of Medicine
country: Finland
name: Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, School of Medicine , Tampere, Finland
last_name: Salmi
first_name: Marko
name: Marko Salmi
affiliations: label: 4
institution: National Institute for Health and Welfare
country: Finland
name: National Institute for Health and Welfare , Finland
label: 7
institution: MediCity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku
country: Finland
name: MediCity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku , Turku, Finland
last_name: Maksimow
first_name: Mikael
name: Mikael Maksimow
affiliations: label: 4
institution: National Institute for Health and Welfare
country: Finland
name: National Institute for Health and Welfare , Finland
label: 7
institution: MediCity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku
country: Finland
name: MediCity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku , Turku, Finland
last_name: Männistö
first_name: Satu
name: Satu Männistö
affiliations: label: 4
institution: National Institute for Health and Welfare
country: Finland
name: National Institute for Health and Welfare , Finland
last_name: Kähönen
first_name: Mika
name: Mika Kähönen
affiliations: label: 9
institution: Department of Clinical Physiology, University of Tampere and Tampere University Hospital
name: Department of Clinical Physiology, University of Tampere and Tampere University Hospital , Tampere
last_name: Juonala
first_name: Markus
name: Markus Juonala
affiliations: label: 10
institution: Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital
country: Finland
name: 10 Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital , Turku, Finland
label: 11
institution: Murdoch Childrens Research Institute
country: Australia
name: 11 Murdoch Childrens Research Institute , Parkville, Victoria, Australia
last_name: Lehtimäki
first_name: Terho
name: Terho Lehtimäki
affiliations: label: 8
institution: Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, School of Medicine
country: Finland
name: Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, School of Medicine , Tampere, Finland
last_name: Jalkanen
first_name: Sirpa
name: Sirpa Jalkanen
affiliations: label: 7
institution: MediCity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku
country: Finland
name: MediCity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku , Turku, Finland
last_name: Perola
first_name: Markus
name: Markus Perola
affiliations: label: 4
institution: National Institute for Health and Welfare
country: Finland
name: National Institute for Health and Welfare , Finland
label: 5
institution: Institute for Molecular Medicine Finland, University of Helsinki
country: Finland
name: Institute for Molecular Medicine Finland, University of Helsinki , Helsinki, Finland
last_name: Raitakari
first_name: Olli
name: Olli Raitakari
affiliations: label: 12
institution: Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital
country: Finland
name: 12 Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital , Turku, Finland
label: 13
institution: Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku
country: Finland
name: 13 Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku , Turku, Finland
last_name: Salomaa
first_name: Veikko
name: Veikko Salomaa
affiliations: label: 4
institution: National Institute for Health and Welfare
country: Finland
name: National Institute for Health and Welfare , Finland
last_name: Ala-Korpela
first_name: Mika
name: Mika Ala-Korpela
affiliations: label: 3
institution: Computational Medicine, Institute of Health Sciences, University of Oulu
country: Finland
name: Computational Medicine, Institute of Health Sciences, University of Oulu , Oulu, Finland
label: 6
institution: NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland
country: Finland
name: NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland , Kuopio, Finland
label: 14
institution: Oulu University Hospital
country: Finland
name: 14 Oulu University Hospital , Oulu, Finland
label: 15
institution: Computational Medicine, School of Social and Community Medicine, University of Bristol
country: United Kingdom
name: 15 Computational Medicine, School of Social and Community Medicine, University of Bristol , Bristol, United Kingdom
label: 16
institution: Medical Research Council Integrative Epidemiology Unit at the University of Bristol
country: United Kingdom
name: 16 Medical Research Council Integrative Epidemiology Unit at the University of Bristol , Bristol, United Kingdom
last_name: Kettunen
first_name: Johannes
name: Johannes Kettunen
corresponding: yes
affiliations: label: 3
institution: Computational Medicine, Institute of Health Sciences, University of Oulu
country: Finland
name: Computational Medicine, Institute of Health Sciences, University of Oulu , Oulu, Finland
label: 4
institution: National Institute for Health and Welfare
country: Finland
name: National Institute for Health and Welfare , Finland
label: 6
institution: NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland
country: Finland
name: NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland , Kuopio, Finland
last_name: Inouye
first_name: Michael
name: Michael Inouye
corresponding: yes
affiliations: label: 1
institution: Centre for Systems Genomics, School of Biological Sciences, The University of Melbourne
country: Australia
name: Centre for Systems Genomics, School of Biological Sciences, The University of Melbourne , Parkville 3010, Victoria, Australia
label: 2
institution: Department of Pathology, The University of Melbourne
country: Australia
name: Department of Pathology, The University of Melbourne , Parkville 3010, Victoria, Australia
Affiliations: label: 1
institution: Centre for Systems Genomics, School of Biological Sciences, The University of Melbourne
country: Australia
name: Centre for Systems Genomics, School of Biological Sciences, The University of Melbourne , Parkville 3010, Victoria, Australia
label: 2
institution: Department of Pathology, The University of Melbourne
country: Australia
name: Department of Pathology, The University of Melbourne , Parkville 3010, Victoria, Australia
label: 3
institution: Computational Medicine, Institute of Health Sciences, University of Oulu
country: Finland
name: Computational Medicine, Institute of Health Sciences, University of Oulu , Oulu, Finland
label: 4
institution: National Institute for Health and Welfare
country: Finland
name: National Institute for Health and Welfare , Finland
label: 5
institution: Institute for Molecular Medicine Finland, University of Helsinki
country: Finland
name: Institute for Molecular Medicine Finland, University of Helsinki , Helsinki, Finland
label: 6
institution: NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland
country: Finland
name: NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland , Kuopio, Finland
label: 7
institution: MediCity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku
country: Finland
name: MediCity Research Laboratory, Department of Medical Microbiology and Immunology, University of Turku , Turku, Finland
label: 8
institution: Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, School of Medicine
country: Finland
name: Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere, School of Medicine , Tampere, Finland
label: 9
institution: Department of Clinical Physiology, University of Tampere and Tampere University Hospital
name: Department of Clinical Physiology, University of Tampere and Tampere University Hospital , Tampere
label: 10
institution: Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital
country: Finland
name: 10 Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital , Turku, Finland
label: 11
institution: Murdoch Childrens Research Institute
country: Australia
name: 11 Murdoch Childrens Research Institute , Parkville, Victoria, Australia
label: 12
institution: Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital
country: Finland
name: 12 Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital , Turku, Finland
label: 13
institution: Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku
country: Finland
name: 13 Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku , Turku, Finland
label: 14
institution: Oulu University Hospital
country: Finland
name: 14 Oulu University Hospital , Oulu, Finland
label: 15
institution: Computational Medicine, School of Social and Community Medicine, University of Bristol
country: United Kingdom
name: 15 Computational Medicine, School of Social and Community Medicine, University of Bristol , Bristol, United Kingdom
label: 16
institution: Medical Research Council Integrative Epidemiology Unit at the University of Bristol
country: United Kingdom
name: 16 Medical Research Council Integrative Epidemiology Unit at the University of Bristol , Bristol, United Kingdom
Field: Biochemistry, Genetics and Molecular Biology
Document type: preprint
Year: 2015