Title: Low frequency and rare coding variation contributes to multiple sclerosis risk
Authors: last_name: Mitrovic
first_name: Mitja
name: Mitja Mitrovic
affiliations: label: 2
institution: Yale School of Medicine;
name: Yale School of Medicine;
orcid: http://orcid.org/0000-0003-3757-8941
last_name: Patsopoulos
first_name: Nikolaos
name: Nikolaos Patsopoulos
affiliations: label: 3
institution: Brigham & Women’s Hospital
name: Brigham & Women’s Hospital , Boston, MA;
last_name: Beecham
first_name: Ashley
name: Ashley Beecham
affiliations: label: 4
institution: University of Miami, Miller School of Medicine
name: University of Miami, Miller School of Medicine , Miami, FL;
orcid: http://orcid.org/0000-0002-1315-9454
last_name: Dankowski
first_name: Theresa
name: Theresa Dankowski
affiliations: label: 5
institution: Institute of Medical Biometry and Statistics, University of Lubeck
name: Institute of Medical Biometry and Statistics, University of Lubeck , Germany;
orcid: http://orcid.org/0000-0002-1276-6682
last_name: Goris
first_name: An
name: An Goris
affiliations: label: 6
institution: Department of Neurosciences, Laboratory for Neuroimmunology
name: Department of Neurosciences, Laboratory for Neuroimmunology , Leuven, Belgium;
last_name: Dubois
first_name: Benedicte
name: Benedicte Dubois
affiliations: label: 6
institution: Department of Neurosciences, Laboratory for Neuroimmunology
name: Department of Neurosciences, Laboratory for Neuroimmunology , Leuven, Belgium;
orcid: http://orcid.org/0000-0002-0917-4176
last_name: Dhooghe
first_name: Marie-Beatrice
name: Marie-Beatrice Dhooghe
affiliations: label: 7
institution: National Multiple Sclerosis Center
name: National Multiple Sclerosis Center , Melsbroek, Belgium;
orcid: http://orcid.org/0000-0002-4948-5956
last_name: Lemmens
first_name: Robin
name: Robin Lemmens
affiliations: label: 6
institution: Department of Neurosciences, Laboratory for Neuroimmunology
name: Department of Neurosciences, Laboratory for Neuroimmunology , Leuven, Belgium;
orcid: http://orcid.org/0000-0001-6384-0611
last_name: Van Damme
first_name: Philip
name: Philip Van Damme
affiliations: label: 6
institution: Department of Neurosciences, Laboratory for Neuroimmunology
name: Department of Neurosciences, Laboratory for Neuroimmunology , Leuven, Belgium;
last_name: Fitzgerald
first_name: Kate
name: Kate Fitzgerald
affiliations: label: 8
institution: Department of Neurology, Johns Hopkins University School of Medicine
name: Department of Neurology, Johns Hopkins University School of Medicine , Baltimore MD;
last_name: Bach Sondergaard
first_name: Helle
name: Helle Bach Sondergaard
affiliations: label: 9
institution: Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen;
name: Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen;
orcid: http://orcid.org/0000-0002-1333-9623
last_name: Sellebjerg
first_name: Finn
name: Finn Sellebjerg
affiliations: label: 9
institution: Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen;
name: Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen;
orcid: http://orcid.org/0000-0002-2818-3780
last_name: Sorensen
first_name: Per Soelberg
name: Per Soelberg Sorensen
affiliations: label: 9
institution: Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen;
name: Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen;
last_name: Ullum
first_name: Henrik
name: Henrik Ullum
affiliations: label: 10
institution: Department of Clinical Immunology, Rigshospitalet, University of Copenhagen
name: 10 Department of Clinical Immunology, Rigshospitalet, University of Copenhagen , Denmark;
orcid: http://orcid.org/0000-0003-4391-4956
last_name: Wegner Thoerner
first_name: Lise
name: Lise Wegner Thoerner
affiliations: label: 11
institution: Department of Clinical Immunology, Center of Clinical Investigation, Copenhagen University Hospital;
name: 11 Department of Clinical Immunology, Center of Clinical Investigation, Copenhagen University Hospital;
orcid: http://orcid.org/0000-0003-1829-0766
last_name: Werge
first_name: Thomas
name: Thomas Werge
affiliations: label: 12
institution: Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Univ of Copenhagen
country: Denmark
name: 12 Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Univ of Copenhagen , Denmark
last_name: Saarela
first_name: Janna
name: Janna Saarela
affiliations: label: 13
institution: Institute for Molecular Medicine Finland, University of Helsinki
country: Finland
name: 13 Institute for Molecular Medicine Finland, University of Helsinki , Helsinki, Finland
orcid: http://orcid.org/0000-0002-9400-0970
last_name: Cournu-Rebeix
first_name: Isabelle
name: Isabelle Cournu-Rebeix
affiliations: label: 14
institution: Departement de Neurologie Pitie-Salpetriere
country: France
name: 14 Departement de Neurologie Pitie-Salpetriere , PARIS, France
orcid: http://orcid.org/0000-0002-7321-8575
last_name: Damotte
first_name: Vincent
name: Vincent Damotte
affiliations: label: 14
institution: Departement de Neurologie Pitie-Salpetriere
country: France
name: 14 Departement de Neurologie Pitie-Salpetriere , PARIS, France
last_name: Fontaine
first_name: Bertrand
name: Bertrand Fontaine
affiliations: label: 14
institution: Departement de Neurologie Pitie-Salpetriere
country: France
name: 14 Departement de Neurologie Pitie-Salpetriere , PARIS, France
last_name: Guillot-Noel
first_name: Lena
name: Lena Guillot-Noel
affiliations: label: 14
institution: Departement de Neurologie Pitie-Salpetriere
country: France
name: 14 Departement de Neurologie Pitie-Salpetriere , PARIS, France
last_name: Lathrop
first_name: Mark
name: Mark Lathrop
affiliations: label: 15
institution: Commissariat a l’Energie Atomique, Institut Genomique, Centre National de Genotypage
country: France
name: 15 Commissariat a l’Energie Atomique, Institut Genomique, Centre National de Genotypage , Evry, France
last_name: Vukusik
first_name: Sandra
name: Sandra Vukusik
affiliations: label: 16
institution: Observatoire Francais de la Sclerose en Plaques (OFSEP) Hopital Neurologique cedex
country: France
name: 16 Observatoire Francais de la Sclerose en Plaques (OFSEP) Hopital Neurologique cedex - France
orcid: http://orcid.org/0000-0003-1131-9554
last_name: Gourraud
first_name: Pierre-Antoine
name: Pierre-Antoine Gourraud
affiliations: label: 17
institution: Universite de Nantes, INSERM, Centre de Recherche en Transplantation et Immunologie
country: France
name: 17 Universite de Nantes, INSERM, Centre de Recherche en Transplantation et Immunologie , Nantes, France
orcid: http://orcid.org/0000-0002-2917-5889
last_name: Andlauer
first_name: Till
name: Till Andlauer
affiliations: label: 18
institution: Max Planck Institute of Psychiatry
country: Germany
name: 18 Max Planck Institute of Psychiatry , 80804 Munich, Germany
last_name: Pongratz
first_name: Viola
name: Viola Pongratz
affiliations: label: 19
institution: Department of Neurology, Klinikum rechts der Isar, Technische Universitat Munchen
country: Germany
name: 19 Department of Neurology, Klinikum rechts der Isar, Technische Universitat Munchen , Germany
last_name: Buck
first_name: Dorothea
name: Dorothea Buck
affiliations: label: 19
institution: Department of Neurology, Klinikum rechts der Isar, Technische Universitat Munchen
country: Germany
name: 19 Department of Neurology, Klinikum rechts der Isar, Technische Universitat Munchen , Germany
orcid: http://orcid.org/0000-0002-0524-6005
last_name: Gasperi
first_name: Christiane
name: Christiane Gasperi
affiliations: label: 19
institution: Department of Neurology, Klinikum rechts der Isar, Technische Universitat Munchen
country: Germany
name: 19 Department of Neurology, Klinikum rechts der Isar, Technische Universitat Munchen , Germany
orcid: http://orcid.org/0000-0001-6647-7889
last_name: Graetz
first_name: Christiane
name: Christiane Graetz
affiliations: label: 20
institution: Johannes Gutenberg University-Medical Center
country: Germany
name: 20 Johannes Gutenberg University-Medical Center , Mainz, Germany
last_name: Bayas
first_name: Antonios
name: Antonios Bayas
affiliations: label: 21
institution: Department of Neurology Klinikum Augsburg
name: 21 Department of Neurology Klinikum Augsburg , Stenglingstr. 2, 86156 Augsburg;
orcid: http://orcid.org/0000-0001-8131-9467
last_name: Heesen
first_name: Christoph
name: Christoph Heesen
affiliations: label: 22
institution: Department of Neurology, Universitatsklinikum Hamburg Eppendorf
name: 22 Department of Neurology, Universitatsklinikum Hamburg Eppendorf , Martinistr. 52, 20246 Hamburg;
last_name: Kumpfel
first_name: Tania
name: Tania Kumpfel
affiliations: label: 23
institution: Department of Neuroimmunology, Klinikum GroBhadern
name: 23 Department of Neuroimmunology, Klinikum GroBhadern , Marchioninistr.15, 81377 Munchen;
orcid: http://orcid.org/0000-0001-9775-3719
last_name: Linker
first_name: Ralf
name: Ralf Linker
affiliations: label: 24
institution: Department of Neurology Universitatsklinikum Erlangen
name: 24 Department of Neurology Universitatsklinikum Erlangen , Maximiliansplatz 2, 91054 Erlangen;
last_name: Paul
first_name: Friedemann
name: Friedemann Paul
affiliations: label: 25
institution: NeruoCure Clinical Research Center
name: 25 NeruoCure Clinical Research Center , Charite Campus Mitte Chariteplatz 1, 10117 Berlin;
orcid: http://orcid.org/0000-0003-2504-5398
last_name: Stangel
first_name: Martin
name: Martin Stangel
affiliations: label: 26
institution: Department of Neurology, Medizinische Hochschule Hannover
name: 26 Department of Neurology, Medizinische Hochschule Hannover , Carl-Neuberg-Str. 1, 30625 Hannover;
last_name: Tackenberg
first_name: Bjorn
name: Bjorn Tackenberg
affiliations: label: 27
institution: Department of Neurology, Universitatsklinikum GieBen/Marburg
name: 27 Department of Neurology, Universitatsklinikum GieBen/Marburg , Baldingerstr., 35043 Marburg;
last_name: Then Bergh
first_name: Florian
name: Florian Then Bergh
affiliations: label: 28
institution: Department of Neurology, Universitatsklinikum Leipzig
name: 28 Department of Neurology, Universitatsklinikum Leipzig , Liebigstr. 20, 04103 Leipzig;
last_name: Warnke
first_name: Clemens
name: Clemens Warnke
affiliations: label: 29
institution: Department of Neurology, Universitatsklinikum Koln
name: 29 Department of Neurology, Universitatsklinikum Koln , Kerpener Str. 62, 50937 Koln;
orcid: http://orcid.org/0000-0001-5509-1075
last_name: Wiendl
first_name: Heinz
name: Heinz Wiendl
affiliations: label: 30
institution: Department of Neurology, Universitatsklinikum Munster
name: 30 Department of Neurology, Universitatsklinikum Munster , Albert-Schweitzer-Campus 1, 48149 Munster;
last_name: Wildemann
first_name: Brigitte
name: Brigitte Wildemann
affiliations: label: 31
institution: Department of Neurology, Universitatsklinikum Heidelberg
name: 31 Department of Neurology, Universitatsklinikum Heidelberg , Im Neuenheimer Feld 400, 69120 Heidelberg;
last_name: Zettl
first_name: Uwe
name: Uwe Zettl
affiliations: label: 32
institution: Department of Neurology, Universitatsklinikum Rostock
name: 32 Department of Neurology, Universitatsklinikum Rostock , Schillingallee 35, 18057 Rostock;
last_name: Ziemann
first_name: Ulf
name: Ulf Ziemann
affiliations: label: 33
institution: Department of Neurology, Universitatsklinikum Tubingen
name: 33 Department of Neurology, Universitatsklinikum Tubingen , Tubingen;
orcid: http://orcid.org/0000-0002-7921-9966
last_name: Tumani
first_name: Hayrettin
name: Hayrettin Tumani
affiliations: label: 34
institution: Fachklinik fur Neurologie, Akademisches Krankenhaus der Universitat Ulm
name: 34 Fachklinik fur Neurologie, Akademisches Krankenhaus der Universitat Ulm , Dietenbronn 7, 88477 Schwen;
last_name: Gold
first_name: Ralf
name: Ralf Gold
affiliations: label: 35
institution: Department of Neurology, Ruhr Universitat Bochum, St. Josef Hospital
name: 35 Department of Neurology, Ruhr Universitat Bochum, St. Josef Hospital , Gudrunstr. 56, 44791 Bochum;
last_name: Grummel
first_name: Verena
name: Verena Grummel
affiliations: label: 19
institution: Department of Neurology, Klinikum rechts der Isar, Technische Universitat Munchen
country: Germany
name: 19 Department of Neurology, Klinikum rechts der Isar, Technische Universitat Munchen , Germany
orcid: http://orcid.org/0000-0001-5985-6784
last_name: Hemmer
first_name: Bernhard
name: Bernhard Hemmer
affiliations: label: 19
institution: Department of Neurology, Klinikum rechts der Isar, Technische Universitat Munchen
country: Germany
name: 19 Department of Neurology, Klinikum rechts der Isar, Technische Universitat Munchen , Germany
orcid: http://orcid.org/0000-0003-4187-9472
last_name: Knier
first_name: Benjamin
name: Benjamin Knier
affiliations: label: 19
institution: Department of Neurology, Klinikum rechts der Isar, Technische Universitat Munchen
country: Germany
name: 19 Department of Neurology, Klinikum rechts der Isar, Technische Universitat Munchen , Germany
orcid: http://orcid.org/0000-0002-1903-6762
last_name: Lill
first_name: Christina
name: Christina Lill
affiliations: label: 36
institution: Department of Neurology, University Medical Center of the Johannes Gutenberg Mainz
country: Germany
name: 36 Department of Neurology, University Medical Center of the Johannes Gutenberg Mainz , Germany
last_name: Luessi
first_name: Efthimios
name: Efthimios Luessi
affiliations: label: 36
institution: Department of Neurology, University Medical Center of the Johannes Gutenberg Mainz
country: Germany
name: 36 Department of Neurology, University Medical Center of the Johannes Gutenberg Mainz , Germany
orcid: http://orcid.org/0000-0002-1862-7499
last_name: Dardiotis
first_name: Efthimios
name: Efthimios Dardiotis
affiliations: label: 37
institution: Neurology Dpt, Neurogenetics Lab, University Hospital of Larissa
country: Greece
name: 37 Neurology Dpt, Neurogenetics Lab, University Hospital of Larissa , Greece
orcid: http://orcid.org/0000-0003-2022-3386
last_name: Agliardi
first_name: Cristina
name: Cristina Agliardi
affiliations: label: 38
institution: Laboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi Foundation ONLUS
country: Italy
name: 38 Laboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi Foundation ONLUS , Milan, Italy
orcid: http://orcid.org/0000-0002-2090-5638
last_name: Barizzone
first_name: Nadia
name: Nadia Barizzone
affiliations: label: 39
institution: Department of Health Sciences and IRCAD, University of Eastern Piedmont
country: Italy
name: 39 Department of Health Sciences and IRCAD, University of Eastern Piedmont , Novara, Italy
last_name: Mascia
first_name: Elisabetta
name: Elisabetta Mascia
affiliations: label: 40
institution: Division of Neuroscience, San Raffaele Scientific Institute
country: Italy
name: 40 Division of Neuroscience, San Raffaele Scientific Institute , Via Olgettina 58, 20132, Milan, Italy
orcid: http://orcid.org/0000-0002-7551-6664
last_name: Bernardinelli
first_name: Luisa
name: Luisa Bernardinelli
affiliations: label: 41
institution: Medical Research Council Biostatistics Unit
country: UK
name: 41 Medical Research Council Biostatistics Unit , Robinson Way, Cambridge CB2 0SR, UK
orcid: http://orcid.org/0000-0002-6989-1054
last_name: Comi
first_name: Giancarlo
name: Giancarlo Comi
affiliations: label: 40
institution: Division of Neuroscience, San Raffaele Scientific Institute
country: Italy
name: 40 Division of Neuroscience, San Raffaele Scientific Institute , Via Olgettina 58, 20132, Milan, Italy
orcid: http://orcid.org/0000-0002-1006-7597
last_name: Cusi
first_name: Daniele
name: Daniele Cusi
affiliations: label: 42
institution: University of Milan, Department of Health Sciences
country: Italy
name: 42 University of Milan, Department of Health Sciences , Milan, Italy
last_name: Esposito
first_name: Federica
name: Federica Esposito
affiliations: label: 40
institution: Division of Neuroscience, San Raffaele Scientific Institute
country: Italy
name: 40 Division of Neuroscience, San Raffaele Scientific Institute , Via Olgettina 58, 20132, Milan, Italy
orcid: http://orcid.org/0000-0002-0559-5301
last_name: Ferre
first_name: Laura
name: Laura Ferre
affiliations: label: 40
institution: Division of Neuroscience, San Raffaele Scientific Institute
country: Italy
name: 40 Division of Neuroscience, San Raffaele Scientific Institute , Via Olgettina 58, 20132, Milan, Italy
orcid: http://orcid.org/0000-0002-6862-9468
last_name: Comi
first_name: Cristoforo
name: Cristoforo Comi
affiliations: label: 43
institution: University of Eastern Piedmont
country: Italy
name: 43 University of Eastern Piedmont , Novara, Italy
last_name: Galimberti
first_name: Daniela
name: Daniela Galimberti
affiliations: label: 44
institution: Neurology Unit, Dept. of Pathophysiology and Transplantation, University of Milan
name: 44 Neurology Unit, Dept. of Pathophysiology and Transplantation, University of Milan
last_name: Leone
first_name: Maurizio
name: Maurizio Leone
affiliations: label: 45
institution: Department of Neurology, Ospedale Maggiore
country: Italy
name: 45 Department of Neurology, Ospedale Maggiore , Novara, Italy
orcid: http://orcid.org/0000-0003-4376-2550
last_name: Sorosina
first_name: Melissa
name: Melissa Sorosina
affiliations: label: 40
institution: Division of Neuroscience, San Raffaele Scientific Institute
country: Italy
name: 40 Division of Neuroscience, San Raffaele Scientific Institute , Via Olgettina 58, 20132, Milan, Italy
orcid: http://orcid.org/0000-0002-9595-2914
last_name: Mescheriakova
first_name: Julia Y
name: Julia Y Mescheriakova
affiliations: label: 46
institution: Department of Neurology, Erasmus MC
country: Netherlands
name: 46 Department of Neurology, Erasmus MC , Rotterdam, Netherlands
orcid: http://orcid.org/0000-0003-2585-3643
last_name: Hintzen
first_name: Rogier
name: Rogier Hintzen
affiliations: label: 46
institution: Department of Neurology, Erasmus MC
country: Netherlands
name: 46 Department of Neurology, Erasmus MC , Rotterdam, Netherlands
orcid: http://orcid.org/0000-0002-2374-9204
last_name: Van Duijn
first_name: Cornelia
name: Cornelia Van Duijn
affiliations: label: 46
institution: Department of Neurology, Erasmus MC
country: Netherlands
name: 46 Department of Neurology, Erasmus MC , Rotterdam, Netherlands
last_name: Bos
first_name: Steffan
name: Steffan Bos
affiliations: label: 47
institution: Department of Neurology, Institute of Clinical Medicine, University of Oslo
country: Norway
name: 47 Department of Neurology, Institute of Clinical Medicine, University of Oslo , Norway
last_name: Myhr
first_name: Kjell-Morten
name: Kjell-Morten Myhr
affiliations: label: 48
institution: Department of Neurology, Haukeland University Hospital
country: Norway
name: 48 Department of Neurology, Haukeland University Hospital , Bergen, Norway
orcid: http://orcid.org/0000-0002-9127-6488
last_name: Celius
first_name: Elisabeth Gulowsen
name: Elisabeth Gulowsen Celius
affiliations: label: 49
institution: Department of Neurology, Oslo University Hospital
country: Norway
name: 49 Department of Neurology, Oslo University Hospital , Oslo Norway
last_name: Lie
first_name: Benedicte
name: Benedicte Lie
affiliations: label: 50
institution: Department of medical genetics, Oslo University Hospitael
name: 50 Department of medical genetics, Oslo University Hospitael
orcid: http://orcid.org/0000-0003-4421-0766
last_name: Spurkland
first_name: Anne
name: Anne Spurkland
affiliations: label: 51
institution: Institute of Basic Medical Sciences, University of Oslo
country: Norway
name: 51 Institute of Basic Medical Sciences, University of Oslo , Norway
last_name: Comabella
first_name: Manuel
name: Manuel Comabella
affiliations: label: 52
institution: Institut de Recerca Vall dHebron (VHIR). Hospital Universitari Vall dHebron
country: Spain
name: 52 Institut de Recerca Vall dHebron (VHIR). Hospital Universitari Vall dHebron , Barcelona, Spain
last_name: Montalban
first_name: Xavier
name: Xavier Montalban
affiliations: label: 52
institution: Institut de Recerca Vall dHebron (VHIR). Hospital Universitari Vall dHebron
country: Spain
name: 52 Institut de Recerca Vall dHebron (VHIR). Hospital Universitari Vall dHebron , Barcelona, Spain
orcid: http://orcid.org/0000-0003-1688-6697
last_name: Alfredsson
first_name: Lars
name: Lars Alfredsson
affiliations: label: 53
institution: Institute of Environmental Medicine, Karolinska Institutet
country: Sweden
name: 53 Institute of Environmental Medicine, Karolinska Institutet , Stockholm, Sweden
orcid: http://orcid.org/0000-0003-4855-0039
last_name: Stridh
first_name: Pernilla
name: Pernilla Stridh
affiliations: label: 54
institution: Department of Clinical Neuroscience, Karolinska Institutet
country: Sweden
name: 54 Department of Clinical Neuroscience, Karolinska Institutet , Stockholm, Sweden
orcid: http://orcid.org/0000-0002-7386-6732
last_name: Hillert
first_name: Jan
name: Jan Hillert
affiliations: label: 54
institution: Department of Clinical Neuroscience, Karolinska Institutet
country: Sweden
name: 54 Department of Clinical Neuroscience, Karolinska Institutet , Stockholm, Sweden
orcid: http://orcid.org/0000-0003-0756-889X
last_name: Jagodic
first_name: Maja
name: Maja Jagodic
affiliations: label: 54
institution: Department of Clinical Neuroscience, Karolinska Institutet
country: Sweden
name: 54 Department of Clinical Neuroscience, Karolinska Institutet , Stockholm, Sweden
orcid: http://orcid.org/0000-0001-8329-5219
last_name: Piehl
first_name: Fredrik
name: Fredrik Piehl
affiliations: label: 54
institution: Department of Clinical Neuroscience, Karolinska Institutet
country: Sweden
name: 54 Department of Clinical Neuroscience, Karolinska Institutet , Stockholm, Sweden
orcid: http://orcid.org/0000-0003-3090-7319
last_name: Jelcic
first_name: Ilijas
name: Ilijas Jelcic
affiliations: label: 55
institution: Neuroimmunology and MS Research (nims), Neurology Clinic, University Hospital Zurich
country: Switzerland
name: 55 Neuroimmunology and MS Research (nims), Neurology Clinic, University Hospital Zurich , Switzerland
last_name: Martin
first_name: Roland
name: Roland Martin
affiliations: label: 55
institution: Neuroimmunology and MS Research (nims), Neurology Clinic, University Hospital Zurich
country: Switzerland
name: 55 Neuroimmunology and MS Research (nims), Neurology Clinic, University Hospital Zurich , Switzerland
orcid: http://orcid.org/0000-0001-8333-7423
last_name: Sospedra
first_name: Mireia
name: Mireia Sospedra
affiliations: label: 55
institution: Neuroimmunology and MS Research (nims), Neurology Clinic, University Hospital Zurich
country: Switzerland
name: 55 Neuroimmunology and MS Research (nims), Neurology Clinic, University Hospital Zurich , Switzerland
last_name: Ban
first_name: Maria
name: Maria Ban
affiliations: label: 56
institution: University of Cambridge, Department of Clinical Neurosciences, Addenbrooke’s Hospital
country: UK
name: 56 University of Cambridge, Department of Clinical Neurosciences, Addenbrooke’s Hospital , Cambridge, UK
last_name: Hawkins
first_name: Clive
name: Clive Hawkins
affiliations: label: 57
institution: Keele University Medical School, University Hospital of North Staffordshire
name: 57 Keele University Medical School, University Hospital of North Staffordshire , NY, UK;
orcid: http://orcid.org/0000-0001-5752-2510
last_name: Hysi
first_name: Pirro
name: Pirro Hysi
affiliations: label: 58
institution: Department of Twin Research and Genetic Epidemiology, Kings College London
name: 58 Department of Twin Research and Genetic Epidemiology, Kings College London , London, UK;
last_name: Kalra
first_name: Seema
name: Seema Kalra
affiliations: label: 59
institution: Keele University Medical School, University Hospital of North Midlands
name: 59 Keele University Medical School, University Hospital of North Midlands , Stoke-on-Trent ST4 7NY, UK;
orcid: http://orcid.org/0000-0002-2751-1770
last_name: Karpe
first_name: Fredrik
name: Fredrik Karpe
affiliations: label: 60
institution: Radcliffe Department of Medicine, University of Oxford
name: 60 Radcliffe Department of Medicine, University of Oxford , Oxford, UK;
orcid: http://orcid.org/0000-0003-0330-7844
last_name: Khadake
first_name: Jyoti
name: Jyoti Khadake
affiliations: label: 61
institution: NIHR BioResource, University of Cambridge and Cambridge University Hospitals
name: 61 NIHR BioResource, University of Cambridge and Cambridge University Hospitals , Cambridge, UK;
orcid: http://orcid.org/0000-0003-2507-5802
last_name: Lachance
first_name: Genevieve
name: Genevieve Lachance
affiliations: label: 58
institution: Department of Twin Research and Genetic Epidemiology, Kings College London
name: 58 Department of Twin Research and Genetic Epidemiology, Kings College London , London, UK;
last_name: Neville
first_name: Matthew
name: Matthew Neville
affiliations: label: 60
institution: Radcliffe Department of Medicine, University of Oxford
name: 60 Radcliffe Department of Medicine, University of Oxford , Oxford, UK;
last_name: Santaniello
first_name: Adam
name: Adam Santaniello
affiliations: label: 62
institution: Department of Neurology, University of California
name: 62 Department of Neurology, University of California , San Francisco, CA;
last_name: Caillier
first_name: Stacy
name: Stacy Caillier
affiliations: label: 62
institution: Department of Neurology, University of California
name: 62 Department of Neurology, University of California , San Francisco, CA;
orcid: http://orcid.org/0000-0002-7776-6472
last_name: Calabresi
first_name: Peter
name: Peter Calabresi
affiliations: label: 63
institution: Department of Neurology, Johns Hopkins University School of medicine
name: 63 Department of Neurology, Johns Hopkins University School of medicine , Baltimore MD;
orcid: http://orcid.org/0000-0001-7689-2533
last_name: Cree
first_name: Bruce
name: Bruce Cree
affiliations: label: 62
institution: Department of Neurology, University of California
name: 62 Department of Neurology, University of California , San Francisco, CA;
last_name: Cross
first_name: Anne
name: Anne Cross
affiliations: label: 64
institution: Multiple Sclerosis Center, Dept of Neurology, School of Medicine, Washington University St Louis
name: 64 Multiple Sclerosis Center, Dept of Neurology, School of Medicine, Washington University St Louis , MO;
last_name: Davis
first_name: Mary
name: Mary Davis
affiliations: label: 65
institution: Center for Human Genetics Research, Vanderbilt University Medical Center
name: 65 Center for Human Genetics Research, Vanderbilt University Medical Center , Nashville, TN;
last_name: Haines
first_name: Jonathan
name: Jonathan Haines
affiliations: label: 65
institution: Center for Human Genetics Research, Vanderbilt University Medical Center
name: 65 Center for Human Genetics Research, Vanderbilt University Medical Center , Nashville, TN;
orcid: http://orcid.org/0000-0001-7735-7858
last_name: de Bakker
first_name: Paul
name: Paul de Bakker
affiliations: label: 66
institution: Vertex Pharmaceuticals
name: 66 Vertex Pharmaceuticals , Boston MA;
last_name: Delgado
first_name: Silvia
name: Silvia Delgado
affiliations: label: 67
institution: Department of Neurology, University of Miami, Miller School of Medicine
name: 67 Department of Neurology, University of Miami, Miller School of Medicine , Miami, FL;
orcid: http://orcid.org/0000-0002-4865-7998
last_name: Dembele
first_name: Marieme
name: Marieme Dembele
affiliations: label: 63
institution: Department of Neurology, Johns Hopkins University School of medicine
name: 63 Department of Neurology, Johns Hopkins University School of medicine , Baltimore MD;
last_name: Edwards
first_name: Keith
name: Keith Edwards
affiliations: label: 68
institution: MS center of northeastern
name: 68 MS center of northeastern NY 1205 Troy Schenectady Rd, Latham, NY;
orcid: http://orcid.org/0000-0003-2814-7461
last_name: Hakonarson
first_name: Hakon
name: Hakon Hakonarson
affiliations: label: 69
institution: Center for Applied Genomics, The Children’s Hospital of Philadelphia
name: 69 Center for Applied Genomics, The Children’s Hospital of Philadelphia , PA;
last_name: Konidari
first_name: Ioanna
name: Ioanna Konidari
affiliations: label: 4
institution: University of Miami, Miller School of Medicine
name: University of Miami, Miller School of Medicine , Miami, FL;
last_name: Lathi
first_name: Ellen
name: Ellen Lathi
affiliations: label: 70
institution: The Elliot Lewis Center
name: 70 The Elliot Lewis Center , 110 Cedar St, Wellesley MA,;
last_name: Manrique
first_name: Clara
name: Clara Manrique
affiliations: label: 4
institution: University of Miami, Miller School of Medicine
name: University of Miami, Miller School of Medicine , Miami, FL;
orcid: http://orcid.org/0000-0001-7283-8804
last_name: Pericak-Vance
first_name: Margaret
name: Margaret Pericak-Vance
affiliations: label: 4
institution: University of Miami, Miller School of Medicine
name: University of Miami, Miller School of Medicine , Miami, FL;
orcid: http://orcid.org/0000-0002-8760-109X
last_name: Piccio
first_name: Laura
name: Laura Piccio
affiliations: label: 71
institution: Department of neurology, School of medicine, Washington University St Louis
name: 71 Department of neurology, School of medicine, Washington University St Louis , St Louis MO;
last_name: Schaefer
first_name: Cathy
name: Cathy Schaefer
affiliations: label: 72
institution: Kaiser Permanente Divison of Research
name: 72 Kaiser Permanente Divison of Research , Oakland, CA;
last_name: McCabe
first_name: Cristin
name: Cristin McCabe
affiliations: label: 73
institution: Broad Institute of Harvard University and MIT
name: 73 Broad Institute of Harvard University and MIT , Cambridge, MA;
last_name: Weiner
first_name: Howard
name: Howard Weiner
affiliations: label: 74
institution: Department of Neurology, Brigham & Women’s Hospital
name: 74 Department of Neurology, Brigham & Women’s Hospital , Boston. MA;
last_name: Olsson
first_name: Thomas
name: Thomas Olsson
affiliations: label: 54
institution: Department of Clinical Neuroscience, Karolinska Institutet
country: Sweden
name: 54 Department of Clinical Neuroscience, Karolinska Institutet , Stockholm, Sweden
orcid: http://orcid.org/0000-0003-4002-2776
last_name: Hadjigeorgiou
first_name: Georgios
name: Georgios Hadjigeorgiou
affiliations: label: 37
institution: Neurology Dpt, Neurogenetics Lab, University Hospital of Larissa
country: Greece
name: 37 Neurology Dpt, Neurogenetics Lab, University Hospital of Larissa , Greece
last_name: Taylor
first_name: Bruce
name: Bruce Taylor
affiliations: label: 75
institution: Menzies Research Institute Tasmania, University of Tasmania
name: 75 Menzies Research Institute Tasmania, University of Tasmania
last_name: Tajoori
first_name: Lotti
name: Lotti Tajoori
affiliations: label: 76
institution: Health Sciences and Medicine Bond University, Gold Coast Queensland
country: Australia
name: 76 Health Sciences and Medicine Bond University, Gold Coast Queensland , Australia
orcid: http://orcid.org/0000-0001-6201-3518
last_name: Charlesworth
first_name: Jac
name: Jac Charlesworth
affiliations: label: 77
institution: Menzies Institute for Medical Research, University of Tasmania
name: 77 Menzies Institute for Medical Research, University of Tasmania
last_name: Booth
first_name: David
name: David Booth
affiliations: label: 78
institution: Westmead Millennium Institute, University of Sydney
name: 78 Westmead Millennium Institute, University of Sydney , New South Wales, Australia;
orcid: http://orcid.org/0000-0002-6047-0122
last_name: Harbo
first_name: Hanne Flinstad
name: Hanne Flinstad Harbo
affiliations: label: 79
institution: Department of Neurology, Oslo University Hospital
name: 79 Department of Neurology, Oslo University Hospital , Oslo, Norway;
last_name: Ivinson
first_name: Adrian
name: Adrian Ivinson
affiliations: label: 80
institution: Department of Neurology, Brigham & Women’s Hospital
name: 80 Department of Neurology, Brigham & Women’s Hospital , Boston, MA;
last_name: Hauser
first_name: Stephen
name: Stephen Hauser
affiliations: label: 81
institution: Department of Neurology, University of California at San Francisco
name: 81 Department of Neurology, University of California at San Francisco , CA;
orcid: http://orcid.org/0000-0002-0734-0185
last_name: Compston
first_name: Alastair
name: Alastair Compston
affiliations: label: 81
institution: Department of Neurology, University of California at San Francisco
name: 81 Department of Neurology, University of California at San Francisco , CA;
last_name: Stewart
first_name: Graeme
name: Graeme Stewart
affiliations: label: 78
institution: Westmead Millennium Institute, University of Sydney
name: 78 Westmead Millennium Institute, University of Sydney , New South Wales, Australia;
orcid: http://orcid.org/0000-0002-1231-1928
last_name: Zipp
first_name: Frauke
name: Frauke Zipp
affiliations: label: 20
institution: Johannes Gutenberg University-Medical Center
country: Germany
name: 20 Johannes Gutenberg University-Medical Center , Mainz, Germany
last_name: Barcellos
first_name: Lisa
name: Lisa Barcellos
affiliations: label: 82
institution: UC Berkeley School of Public Health and Center for Computational Biology
name: 82 UC Berkeley School of Public Health and Center for Computational Biology
orcid: http://orcid.org/0000-0003-0067-194X
last_name: Baranzini
first_name: Sergio
name: Sergio Baranzini
affiliations: label: 81
institution: Department of Neurology, University of California at San Francisco
name: 81 Department of Neurology, University of California at San Francisco , CA;
orcid: http://orcid.org/0000-0001-8326-2249
last_name: Martinelli Boneschi
first_name: Filippo
name: Filippo Martinelli Boneschi
affiliations: label: 83
institution: Division of Neuroscience, San Raffaele Scientific Institute
country: Italy
name: 83 Division of Neuroscience, San Raffaele Scientific Institute , Milan, Italy
orcid: http://orcid.org/0000-0002-3983-9925
last_name: D'Alfonso
first_name: Sandra
name: Sandra D'Alfonso
affiliations: label: 43
institution: University of Eastern Piedmont
country: Italy
name: 43 University of Eastern Piedmont , Novara, Italy
orcid: http://orcid.org/0000-0002-8386-5397
last_name: Ziegler
first_name: Andreas
name: Andreas Ziegler
affiliations: label: 84
institution: University of Lubeck, University Medical Center Schleswig-Holstein
name: 84 University of Lubeck, University Medical Center Schleswig-Holstein , Lubeck;
last_name: Oturai
first_name: Annette
name: Annette Oturai
affiliations: label: 85
institution: Danish Multiple Sclerosis Center, Department of Neurology, University of Copenhagen
name: 85 Danish Multiple Sclerosis Center, Department of Neurology, University of Copenhagen , Denmark;
orcid: http://orcid.org/0000-0002-1805-1733
last_name: McCauley
first_name: Jacob
name: Jacob McCauley
affiliations: label: 4
institution: University of Miami, Miller School of Medicine
name: University of Miami, Miller School of Medicine , Miami, FL;
orcid: http://orcid.org/0000-0001-7685-0974
last_name: Sawcer
first_name: Stephen
name: Stephen Sawcer
affiliations: label: 56
institution: University of Cambridge, Department of Clinical Neurosciences, Addenbrooke’s Hospital
country: UK
name: 56 University of Cambridge, Department of Clinical Neurosciences, Addenbrooke’s Hospital , Cambridge, UK
last_name: Oksenberg
first_name: Jorge
name: Jorge Oksenberg
affiliations: label: 81
institution: Department of Neurology, University of California at San Francisco
name: 81 Department of Neurology, University of California at San Francisco , CA;
last_name: De Jager
first_name: Philip
name: Philip De Jager
affiliations: label: 86
institution: Department of Neurology, Columbia University Medical Center
name: 86 Department of Neurology, Columbia University Medical Center , New York, NY;
orcid: http://orcid.org/0000-0002-0867-4726
last_name: Kockum
first_name: Ingrid
name: Ingrid Kockum
affiliations: label: 54
institution: Department of Clinical Neuroscience, Karolinska Institutet
country: Sweden
name: 54 Department of Clinical Neuroscience, Karolinska Institutet , Stockholm, Sweden
last_name: Hafler
first_name: David
name: David Hafler
affiliations: label: 87
institution: Departments of Neurology and Immunobiology, Yale University School of Medicine
name: 87 Departments of Neurology and Immunobiology, Yale University School of Medicine , New Haven, CT
orcid: http://orcid.org/0000-0002-7772-5910
last_name: Cotsapas
first_name: Chris
name: Chris Cotsapas
corresponding: yes
affiliations: label: 2
institution: Yale School of Medicine;
name: Yale School of Medicine;
Affiliations: label: 2
institution: Yale School of Medicine;
name: Yale School of Medicine;
label: 3
institution: Brigham & Women’s Hospital
name: Brigham & Women’s Hospital , Boston, MA;
label: 4
institution: University of Miami, Miller School of Medicine
name: University of Miami, Miller School of Medicine , Miami, FL;
label: 5
institution: Institute of Medical Biometry and Statistics, University of Lubeck
name: Institute of Medical Biometry and Statistics, University of Lubeck , Germany;
label: 6
institution: Department of Neurosciences, Laboratory for Neuroimmunology
name: Department of Neurosciences, Laboratory for Neuroimmunology , Leuven, Belgium;
label: 7
institution: National Multiple Sclerosis Center
name: National Multiple Sclerosis Center , Melsbroek, Belgium;
label: 8
institution: Department of Neurology, Johns Hopkins University School of Medicine
name: Department of Neurology, Johns Hopkins University School of Medicine , Baltimore MD;
label: 9
institution: Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen;
name: Danish Multiple Sclerosis Center, Department of Neurology, Rigshospitalet, University of Copenhagen;
label: 10
institution: Department of Clinical Immunology, Rigshospitalet, University of Copenhagen
name: 10 Department of Clinical Immunology, Rigshospitalet, University of Copenhagen , Denmark;
label: 11
institution: Department of Clinical Immunology, Center of Clinical Investigation, Copenhagen University Hospital;
name: 11 Department of Clinical Immunology, Center of Clinical Investigation, Copenhagen University Hospital;
label: 12
institution: Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Univ of Copenhagen
country: Denmark
name: 12 Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Univ of Copenhagen , Denmark
label: 13
institution: Institute for Molecular Medicine Finland, University of Helsinki
country: Finland
name: 13 Institute for Molecular Medicine Finland, University of Helsinki , Helsinki, Finland
label: 14
institution: Departement de Neurologie Pitie-Salpetriere
country: France
name: 14 Departement de Neurologie Pitie-Salpetriere , PARIS, France
label: 15
institution: Commissariat a l’Energie Atomique, Institut Genomique, Centre National de Genotypage
country: France
name: 15 Commissariat a l’Energie Atomique, Institut Genomique, Centre National de Genotypage , Evry, France
label: 16
institution: Observatoire Francais de la Sclerose en Plaques (OFSEP) Hopital Neurologique cedex
country: France
name: 16 Observatoire Francais de la Sclerose en Plaques (OFSEP) Hopital Neurologique cedex - France
label: 17
institution: Universite de Nantes, INSERM, Centre de Recherche en Transplantation et Immunologie
country: France
name: 17 Universite de Nantes, INSERM, Centre de Recherche en Transplantation et Immunologie , Nantes, France
label: 18
institution: Max Planck Institute of Psychiatry
country: Germany
name: 18 Max Planck Institute of Psychiatry , 80804 Munich, Germany
label: 19
institution: Department of Neurology, Klinikum rechts der Isar, Technische Universitat Munchen
country: Germany
name: 19 Department of Neurology, Klinikum rechts der Isar, Technische Universitat Munchen , Germany
label: 20
institution: Johannes Gutenberg University-Medical Center
country: Germany
name: 20 Johannes Gutenberg University-Medical Center , Mainz, Germany
label: 21
institution: Department of Neurology Klinikum Augsburg
name: 21 Department of Neurology Klinikum Augsburg , Stenglingstr. 2, 86156 Augsburg;
label: 22
institution: Department of Neurology, Universitatsklinikum Hamburg Eppendorf
name: 22 Department of Neurology, Universitatsklinikum Hamburg Eppendorf , Martinistr. 52, 20246 Hamburg;
label: 23
institution: Department of Neuroimmunology, Klinikum GroBhadern
name: 23 Department of Neuroimmunology, Klinikum GroBhadern , Marchioninistr.15, 81377 Munchen;
label: 24
institution: Department of Neurology Universitatsklinikum Erlangen
name: 24 Department of Neurology Universitatsklinikum Erlangen , Maximiliansplatz 2, 91054 Erlangen;
label: 25
institution: NeruoCure Clinical Research Center
name: 25 NeruoCure Clinical Research Center , Charite Campus Mitte Chariteplatz 1, 10117 Berlin;
label: 26
institution: Department of Neurology, Medizinische Hochschule Hannover
name: 26 Department of Neurology, Medizinische Hochschule Hannover , Carl-Neuberg-Str. 1, 30625 Hannover;
label: 27
institution: Department of Neurology, Universitatsklinikum GieBen/Marburg
name: 27 Department of Neurology, Universitatsklinikum GieBen/Marburg , Baldingerstr., 35043 Marburg;
label: 28
institution: Department of Neurology, Universitatsklinikum Leipzig
name: 28 Department of Neurology, Universitatsklinikum Leipzig , Liebigstr. 20, 04103 Leipzig;
label: 29
institution: Department of Neurology, Universitatsklinikum Koln
name: 29 Department of Neurology, Universitatsklinikum Koln , Kerpener Str. 62, 50937 Koln;
label: 30
institution: Department of Neurology, Universitatsklinikum Munster
name: 30 Department of Neurology, Universitatsklinikum Munster , Albert-Schweitzer-Campus 1, 48149 Munster;
label: 31
institution: Department of Neurology, Universitatsklinikum Heidelberg
name: 31 Department of Neurology, Universitatsklinikum Heidelberg , Im Neuenheimer Feld 400, 69120 Heidelberg;
label: 32
institution: Department of Neurology, Universitatsklinikum Rostock
name: 32 Department of Neurology, Universitatsklinikum Rostock , Schillingallee 35, 18057 Rostock;
label: 33
institution: Department of Neurology, Universitatsklinikum Tubingen
name: 33 Department of Neurology, Universitatsklinikum Tubingen , Tubingen;
label: 34
institution: Fachklinik fur Neurologie, Akademisches Krankenhaus der Universitat Ulm
name: 34 Fachklinik fur Neurologie, Akademisches Krankenhaus der Universitat Ulm , Dietenbronn 7, 88477 Schwen;
label: 35
institution: Department of Neurology, Ruhr Universitat Bochum, St. Josef Hospital
name: 35 Department of Neurology, Ruhr Universitat Bochum, St. Josef Hospital , Gudrunstr. 56, 44791 Bochum;
label: 36
institution: Department of Neurology, University Medical Center of the Johannes Gutenberg Mainz
country: Germany
name: 36 Department of Neurology, University Medical Center of the Johannes Gutenberg Mainz , Germany
label: 37
institution: Neurology Dpt, Neurogenetics Lab, University Hospital of Larissa
country: Greece
name: 37 Neurology Dpt, Neurogenetics Lab, University Hospital of Larissa , Greece
label: 38
institution: Laboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi Foundation ONLUS
country: Italy
name: 38 Laboratory of Molecular Medicine and Biotechnology, Don C. Gnocchi Foundation ONLUS , Milan, Italy
label: 39
institution: Department of Health Sciences and IRCAD, University of Eastern Piedmont
country: Italy
name: 39 Department of Health Sciences and IRCAD, University of Eastern Piedmont , Novara, Italy
label: 40
institution: Division of Neuroscience, San Raffaele Scientific Institute
country: Italy
name: 40 Division of Neuroscience, San Raffaele Scientific Institute , Via Olgettina 58, 20132, Milan, Italy
label: 41
institution: Medical Research Council Biostatistics Unit
country: UK
name: 41 Medical Research Council Biostatistics Unit , Robinson Way, Cambridge CB2 0SR, UK
label: 42
institution: University of Milan, Department of Health Sciences
country: Italy
name: 42 University of Milan, Department of Health Sciences , Milan, Italy
label: 43
institution: University of Eastern Piedmont
country: Italy
name: 43 University of Eastern Piedmont , Novara, Italy
label: 44
institution: Neurology Unit, Dept. of Pathophysiology and Transplantation, University of Milan
name: 44 Neurology Unit, Dept. of Pathophysiology and Transplantation, University of Milan
label: 45
institution: Department of Neurology, Ospedale Maggiore
country: Italy
name: 45 Department of Neurology, Ospedale Maggiore , Novara, Italy
label: 46
institution: Department of Neurology, Erasmus MC
country: Netherlands
name: 46 Department of Neurology, Erasmus MC , Rotterdam, Netherlands
label: 47
institution: Department of Neurology, Institute of Clinical Medicine, University of Oslo
country: Norway
name: 47 Department of Neurology, Institute of Clinical Medicine, University of Oslo , Norway
label: 48
institution: Department of Neurology, Haukeland University Hospital
country: Norway
name: 48 Department of Neurology, Haukeland University Hospital , Bergen, Norway
label: 49
institution: Department of Neurology, Oslo University Hospital
country: Norway
name: 49 Department of Neurology, Oslo University Hospital , Oslo Norway
label: 50
institution: Department of medical genetics, Oslo University Hospitael
name: 50 Department of medical genetics, Oslo University Hospitael
label: 51
institution: Institute of Basic Medical Sciences, University of Oslo
country: Norway
name: 51 Institute of Basic Medical Sciences, University of Oslo , Norway
label: 52
institution: Institut de Recerca Vall dHebron (VHIR). Hospital Universitari Vall dHebron
country: Spain
name: 52 Institut de Recerca Vall dHebron (VHIR). Hospital Universitari Vall dHebron , Barcelona, Spain
label: 53
institution: Institute of Environmental Medicine, Karolinska Institutet
country: Sweden
name: 53 Institute of Environmental Medicine, Karolinska Institutet , Stockholm, Sweden
label: 54
institution: Department of Clinical Neuroscience, Karolinska Institutet
country: Sweden
name: 54 Department of Clinical Neuroscience, Karolinska Institutet , Stockholm, Sweden
label: 55
institution: Neuroimmunology and MS Research (nims), Neurology Clinic, University Hospital Zurich
country: Switzerland
name: 55 Neuroimmunology and MS Research (nims), Neurology Clinic, University Hospital Zurich , Switzerland
label: 56
institution: University of Cambridge, Department of Clinical Neurosciences, Addenbrooke’s Hospital
country: UK
name: 56 University of Cambridge, Department of Clinical Neurosciences, Addenbrooke’s Hospital , Cambridge, UK
label: 57
institution: Keele University Medical School, University Hospital of North Staffordshire
name: 57 Keele University Medical School, University Hospital of North Staffordshire , NY, UK;
label: 58
institution: Department of Twin Research and Genetic Epidemiology, Kings College London
name: 58 Department of Twin Research and Genetic Epidemiology, Kings College London , London, UK;
label: 59
institution: Keele University Medical School, University Hospital of North Midlands
name: 59 Keele University Medical School, University Hospital of North Midlands , Stoke-on-Trent ST4 7NY, UK;
label: 60
institution: Radcliffe Department of Medicine, University of Oxford
name: 60 Radcliffe Department of Medicine, University of Oxford , Oxford, UK;
label: 61
institution: NIHR BioResource, University of Cambridge and Cambridge University Hospitals
name: 61 NIHR BioResource, University of Cambridge and Cambridge University Hospitals , Cambridge, UK;
label: 62
institution: Department of Neurology, University of California
name: 62 Department of Neurology, University of California , San Francisco, CA;
label: 63
institution: Department of Neurology, Johns Hopkins University School of medicine
name: 63 Department of Neurology, Johns Hopkins University School of medicine , Baltimore MD;
label: 64
institution: Multiple Sclerosis Center, Dept of Neurology, School of Medicine, Washington University St Louis
name: 64 Multiple Sclerosis Center, Dept of Neurology, School of Medicine, Washington University St Louis , MO;
label: 65
institution: Center for Human Genetics Research, Vanderbilt University Medical Center
name: 65 Center for Human Genetics Research, Vanderbilt University Medical Center , Nashville, TN;
label: 66
institution: Vertex Pharmaceuticals
name: 66 Vertex Pharmaceuticals , Boston MA;
label: 67
institution: Department of Neurology, University of Miami, Miller School of Medicine
name: 67 Department of Neurology, University of Miami, Miller School of Medicine , Miami, FL;
label: 68
institution: MS center of northeastern
name: 68 MS center of northeastern NY 1205 Troy Schenectady Rd, Latham, NY;
label: 69
institution: Center for Applied Genomics, The Children’s Hospital of Philadelphia
name: 69 Center for Applied Genomics, The Children’s Hospital of Philadelphia , PA;
label: 70
institution: The Elliot Lewis Center
name: 70 The Elliot Lewis Center , 110 Cedar St, Wellesley MA,;
label: 71
institution: Department of neurology, School of medicine, Washington University St Louis
name: 71 Department of neurology, School of medicine, Washington University St Louis , St Louis MO;
label: 72
institution: Kaiser Permanente Divison of Research
name: 72 Kaiser Permanente Divison of Research , Oakland, CA;
label: 73
institution: Broad Institute of Harvard University and MIT
name: 73 Broad Institute of Harvard University and MIT , Cambridge, MA;
label: 74
institution: Department of Neurology, Brigham & Women’s Hospital
name: 74 Department of Neurology, Brigham & Women’s Hospital , Boston. MA;
label: 75
institution: Menzies Research Institute Tasmania, University of Tasmania
name: 75 Menzies Research Institute Tasmania, University of Tasmania
label: 76
institution: Health Sciences and Medicine Bond University, Gold Coast Queensland
country: Australia
name: 76 Health Sciences and Medicine Bond University, Gold Coast Queensland , Australia
label: 77
institution: Menzies Institute for Medical Research, University of Tasmania
name: 77 Menzies Institute for Medical Research, University of Tasmania
label: 78
institution: Westmead Millennium Institute, University of Sydney
name: 78 Westmead Millennium Institute, University of Sydney , New South Wales, Australia;
label: 79
institution: Department of Neurology, Oslo University Hospital
name: 79 Department of Neurology, Oslo University Hospital , Oslo, Norway;
label: 80
institution: Department of Neurology, Brigham & Women’s Hospital
name: 80 Department of Neurology, Brigham & Women’s Hospital , Boston, MA;
label: 81
institution: Department of Neurology, University of California at San Francisco
name: 81 Department of Neurology, University of California at San Francisco , CA;
label: 82
institution: UC Berkeley School of Public Health and Center for Computational Biology
name: 82 UC Berkeley School of Public Health and Center for Computational Biology
label: 83
institution: Division of Neuroscience, San Raffaele Scientific Institute
country: Italy
name: 83 Division of Neuroscience, San Raffaele Scientific Institute , Milan, Italy
label: 84
institution: University of Lubeck, University Medical Center Schleswig-Holstein
name: 84 University of Lubeck, University Medical Center Schleswig-Holstein , Lubeck;
label: 85
institution: Danish Multiple Sclerosis Center, Department of Neurology, University of Copenhagen
name: 85 Danish Multiple Sclerosis Center, Department of Neurology, University of Copenhagen , Denmark;
label: 86
institution: Department of Neurology, Columbia University Medical Center
name: 86 Department of Neurology, Columbia University Medical Center , New York, NY;
label: 87
institution: Departments of Neurology and Immunobiology, Yale University School of Medicine
name: 87 Departments of Neurology and Immunobiology, Yale University School of Medicine , New Haven, CT
Field: Medicine
Document type: preprint
Year: 2018