Title: Observation weights to unlock bulk RNA-seq tools for zero inflation and single-cell applications
Authors: last_name: Van den Berge
first_name: Koen
name: Koen Van den Berge
affiliations: label: 1
institution: Department of Applied Mathematics, Computer Science and Statistics, Ghent University
name: Department of Applied Mathematics, Computer Science and Statistics, Ghent University
label: 2
institution: Bioinformatics Institute Ghent, Ghent University
name: Bioinformatics Institute Ghent, Ghent University
notes: Equal contributor
orcid: http://orcid.org/0000-0003-1478-6983
last_name: Perraudeau
first_name: Fanny
name: Fanny Perraudeau
affiliations: label: 3
institution: Division of Biostatistics, School of Public Health, University of California
name: Division of Biostatistics, School of Public Health, University of California , Berkeley
notes: Equal contributor
orcid: http://orcid.org/0000-0003-3833-2169
last_name: Soneson
first_name: Charlotte
name: Charlotte Soneson
affiliations: label: 4
institution: Institute of Molecular Life Sciences, University of Zurich
name: Institute of Molecular Life Sciences, University of Zurich
label: 5
institution: SIB Swiss Institute of Bioinformatics, University of Zurich
name: SIB Swiss Institute of Bioinformatics, University of Zurich
orcid: http://orcid.org/0000-0001-8401-0545
last_name: Love
first_name: Michael I.
name: Michael I. Love
affiliations: label: 6
institution: Department of Biostatistics and Genetics, The University of North Carolina at Chapel Hill
name: Department of Biostatistics and Genetics, The University of North Carolina at Chapel Hill
orcid: http://orcid.org/0000-0001-8508-5012
last_name: Risso
first_name: Davide
name: Davide Risso
affiliations: label: 7
institution: Division of Biostatistics and Epidemiology, Department of Healthcare Policy and Research, Weill Cornell Medicine
name: Division of Biostatistics and Epidemiology, Department of Healthcare Policy and Research, Weill Cornell Medicine
orcid: http://orcid.org/0000-0001-9510-8441
last_name: Vert
first_name: Jean-Philippe
name: Jean-Philippe Vert
affiliations: label: 8
institution: MINES ParisTech, PSL Research University, CBIO-Centre for Computational Biology
name: MINES ParisTech, PSL Research University, CBIO-Centre for Computational Biology
label: 9
institution: Institut Curie
name: Institut Curie , Paris
label: 10
institution: INSERM U900
name: 10 INSERM U900 , Paris
label: 11
institution: Ecole Normale Supérieure, Department of Mathematics and Applications
name: 11 Ecole Normale Supérieure, Department of Mathematics and Applications
orcid: http://orcid.org/0000-0002-3048-5518
last_name: Robinson
first_name: Mark D.
name: Mark D. Robinson
affiliations: label: 4
institution: Institute of Molecular Life Sciences, University of Zurich
name: Institute of Molecular Life Sciences, University of Zurich
label: 5
institution: SIB Swiss Institute of Bioinformatics, University of Zurich
name: SIB Swiss Institute of Bioinformatics, University of Zurich
orcid: http://orcid.org/0000-0002-6069-8629
last_name: Dudoit
first_name: Sandrine
name: Sandrine Dudoit
corresponding: yes
affiliations: label: 3
institution: Division of Biostatistics, School of Public Health, University of California
name: Division of Biostatistics, School of Public Health, University of California , Berkeley
label: 12
institution: Department of Statistics, University of California
name: 12 Department of Statistics, University of California , Berkeley
notes: Equal contributor
last_name: Clement
first_name: Lieven
name: Lieven Clement
corresponding: yes
affiliations: label: 1
institution: Department of Applied Mathematics, Computer Science and Statistics, Ghent University
name: Department of Applied Mathematics, Computer Science and Statistics, Ghent University
label: 2
institution: Bioinformatics Institute Ghent, Ghent University
name: Bioinformatics Institute Ghent, Ghent University
notes: Equal contributor
Affiliations: label: 1
institution: Department of Applied Mathematics, Computer Science and Statistics, Ghent University
name: Department of Applied Mathematics, Computer Science and Statistics, Ghent University
label: 2
institution: Bioinformatics Institute Ghent, Ghent University
name: Bioinformatics Institute Ghent, Ghent University
label: 3
institution: Division of Biostatistics, School of Public Health, University of California
name: Division of Biostatistics, School of Public Health, University of California , Berkeley
label: 4
institution: Institute of Molecular Life Sciences, University of Zurich
name: Institute of Molecular Life Sciences, University of Zurich
label: 5
institution: SIB Swiss Institute of Bioinformatics, University of Zurich
name: SIB Swiss Institute of Bioinformatics, University of Zurich
label: 6
institution: Department of Biostatistics and Genetics, The University of North Carolina at Chapel Hill
name: Department of Biostatistics and Genetics, The University of North Carolina at Chapel Hill
label: 7
institution: Division of Biostatistics and Epidemiology, Department of Healthcare Policy and Research, Weill Cornell Medicine
name: Division of Biostatistics and Epidemiology, Department of Healthcare Policy and Research, Weill Cornell Medicine
label: 8
institution: MINES ParisTech, PSL Research University, CBIO-Centre for Computational Biology
name: MINES ParisTech, PSL Research University, CBIO-Centre for Computational Biology
label: 9
institution: Institut Curie
name: Institut Curie , Paris
label: 10
institution: INSERM U900
name: 10 INSERM U900 , Paris
label: 11
institution: Ecole Normale Supérieure, Department of Mathematics and Applications
name: 11 Ecole Normale Supérieure, Department of Mathematics and Applications
label: 12
institution: Department of Statistics, University of California
name: 12 Department of Statistics, University of California , Berkeley
Field: Biochemistry, Genetics and Molecular Biology
Document type: preprint
Year: 2018