Title: Multi-omic analysis of urothelial cancer patients treated with PD-L1 blockade demonstrates the contribution of both systemic and somatic factors to the biology of response and resistance
Authors: orcid: http://orcid.org/0000-0002-2606-3523
last_name: Snyder
first_name: Alexandra
name: Alexandra Snyder
affiliations: label: 1
institution: Department of Medicine
name: Department of Medicine , Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine, Weill Cornell Medical College, New York, NY 10065
notes: These authors contributed equally.
orcid: http://orcid.org/0000-0001-6801-5194
last_name: Nathanson
first_name: Tavi
name: Tavi Nathanson
affiliations: label: 2
institution: Department of Genetics and Genomic Sciences
name: Department of Genetics and Genomic Sciences , Icahn School of Medicine at Mount Sinai, New York, NY 10029
notes: These authors contributed equally.
last_name: Funt
first_name: Samuel
name: Samuel Funt
affiliations: label: 1
institution: Department of Medicine
name: Department of Medicine , Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine, Weill Cornell Medical College, New York, NY 10065
notes: These authors contributed equally.
orcid: http://orcid.org/0000-0003-3452-3128
last_name: Ahuja
first_name: Arun
name: Arun Ahuja
affiliations: label: 2
institution: Department of Genetics and Genomic Sciences
name: Department of Genetics and Genomic Sciences , Icahn School of Medicine at Mount Sinai, New York, NY 10029
orcid: http://orcid.org/0000-0001-9588-4889
last_name: Novik
first_name: Jacqueline Buros
name: Jacqueline Buros Novik
affiliations: label: 2
institution: Department of Genetics and Genomic Sciences
name: Department of Genetics and Genomic Sciences , Icahn School of Medicine at Mount Sinai, New York, NY 10029
last_name: Hellmann
first_name: Matthew D.
name: Matthew D. Hellmann
affiliations: label: 1
institution: Department of Medicine
name: Department of Medicine , Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine, Weill Cornell Medical College, New York, NY 10065
orcid: http://orcid.org/0000-0003-3257-8977
last_name: Chang
first_name: Eliza
name: Eliza Chang
affiliations: label: 2
institution: Department of Genetics and Genomic Sciences
name: Department of Genetics and Genomic Sciences , Icahn School of Medicine at Mount Sinai, New York, NY 10029
orcid: http://orcid.org/0000-0002-0135-2505
last_name: Aksoy
first_name: Bulent Arman
name: Bulent Arman Aksoy
affiliations: label: 2
institution: Department of Genetics and Genomic Sciences
name: Department of Genetics and Genomic Sciences , Icahn School of Medicine at Mount Sinai, New York, NY 10029
last_name: Al-Ahmadie
first_name: Hikmat
name: Hikmat Al-Ahmadie
affiliations: label: 3
institution: Department of Pathology
name: Department of Pathology , Memorial Sloan Kettering Cancer Center, New York, NY 10065
last_name: Yusko
first_name: Erik
name: Erik Yusko
affiliations: label: 4
institution: Adaptive Biotechnologies
name: Adaptive Biotechnologies , Seattle, WA 98102
last_name: Vignali
first_name: Marissa
name: Marissa Vignali
affiliations: label: 4
institution: Adaptive Biotechnologies
name: Adaptive Biotechnologies , Seattle, WA 98102
last_name: Benzeno
first_name: Sharon
name: Sharon Benzeno
affiliations: label: 4
institution: Adaptive Biotechnologies
name: Adaptive Biotechnologies , Seattle, WA 98102
last_name: Boyd
first_name: Mariel
name: Mariel Boyd
affiliations: label: 1
institution: Department of Medicine
name: Department of Medicine , Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine, Weill Cornell Medical College, New York, NY 10065
last_name: Moran
first_name: Meredith
name: Meredith Moran
affiliations: label: 1
institution: Department of Medicine
name: Department of Medicine , Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine, Weill Cornell Medical College, New York, NY 10065
last_name: Iyer
first_name: Gopa
name: Gopa Iyer
affiliations: label: 1
institution: Department of Medicine
name: Department of Medicine , Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine, Weill Cornell Medical College, New York, NY 10065
last_name: Robins
first_name: Harlan S.
name: Harlan S. Robins
affiliations: label: 4
institution: Adaptive Biotechnologies
name: Adaptive Biotechnologies , Seattle, WA 98102
label: 5
institution: Fred Hutchinson Cancer Research Center
name: Fred Hutchinson Cancer Research Center , Seattle, Washington 98109
last_name: Mardis
first_name: Elaine R.
name: Elaine R. Mardis
affiliations: label: 6
institution: Institute for Genomic Medicine
name: Institute for Genomic Medicine ; The Research Institute at Nationwide Children's Hospital; The Ohio State University College of Medicine; Columbus, OH 43205
last_name: Merghoub
first_name: Taha
name: Taha Merghoub
affiliations: label: 1
institution: Department of Medicine
name: Department of Medicine , Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine, Weill Cornell Medical College, New York, NY 10065
orcid: http://orcid.org/0000-0001-6596-8563
last_name: Hammerbacher
first_name: Jeff
name: Jeff Hammerbacher
corresponding: yes
affiliations: label: 2
institution: Department of Genetics and Genomic Sciences
name: Department of Genetics and Genomic Sciences , Icahn School of Medicine at Mount Sinai, New York, NY 10029
last_name: Rosenberg
first_name: Jonathan
name: Jonathan Rosenberg
corresponding: yes
affiliations: label: 1
institution: Department of Medicine
name: Department of Medicine , Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine, Weill Cornell Medical College, New York, NY 10065
last_name: Bajorin
first_name: Dean
name: Dean Bajorin
corresponding: yes
affiliations: label: 1
institution: Department of Medicine
name: Department of Medicine , Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine, Weill Cornell Medical College, New York, NY 10065
Affiliations: label: 1
institution: Department of Medicine
name: Department of Medicine , Memorial Sloan Kettering Cancer Center, New York, NY; Department of Medicine, Weill Cornell Medical College, New York, NY 10065
label: 2
institution: Department of Genetics and Genomic Sciences
name: Department of Genetics and Genomic Sciences , Icahn School of Medicine at Mount Sinai, New York, NY 10029
label: 3
institution: Department of Pathology
name: Department of Pathology , Memorial Sloan Kettering Cancer Center, New York, NY 10065
label: 4
institution: Adaptive Biotechnologies
name: Adaptive Biotechnologies , Seattle, WA 98102
label: 5
institution: Fred Hutchinson Cancer Research Center
name: Fred Hutchinson Cancer Research Center , Seattle, Washington 98109
label: 6
institution: Institute for Genomic Medicine
name: Institute for Genomic Medicine ; The Research Institute at Nationwide Children's Hospital; The Ohio State University College of Medicine; Columbus, OH 43205
Field: Medicine
Document type: preprint
Year: 2016