Title: Architecture of a minimal signalling pathway explains the T cell response to a 1,000,000-fold variation in antigen affinity and dose
Authors: last_name: Lever
first_name: Melissa
name: Melissa Lever
affiliations: label: †
institution: Sir William Dunn School of Pathology, University of Oxford
country: Kingdom
name: † Sir William Dunn School of Pathology, University of Oxford , Oxford, United Kingdom
notes: These authors contributed equally
last_name: Lim
first_name: Hong-Sheng
name: Hong-Sheng Lim
affiliations: label: †
institution: Sir William Dunn School of Pathology, University of Oxford
country: Kingdom
name: † Sir William Dunn School of Pathology, University of Oxford , Oxford, United Kingdom
notes: These authors contributed equally
last_name: Kruger
first_name: Philipp
name: Philipp Kruger
affiliations: label: †
institution: Sir William Dunn School of Pathology, University of Oxford
country: Kingdom
name: † Sir William Dunn School of Pathology, University of Oxford , Oxford, United Kingdom
notes: These authors contributed equally
last_name: Nguyen
first_name: John
name: John Nguyen
affiliations: label: †
institution: Sir William Dunn School of Pathology, University of Oxford
country: Kingdom
name: † Sir William Dunn School of Pathology, University of Oxford , Oxford, United Kingdom
last_name: Trendel
first_name: Nicola
name: Nicola Trendel
affiliations: label: †
institution: Sir William Dunn School of Pathology, University of Oxford
country: Kingdom
name: † Sir William Dunn School of Pathology, University of Oxford , Oxford, United Kingdom
last_name: Abu-Shah
first_name: Enas
name: Enas Abu-Shah
affiliations: label: †
institution: Sir William Dunn School of Pathology, University of Oxford
country: Kingdom
name: † Sir William Dunn School of Pathology, University of Oxford , Oxford, United Kingdom
last_name: Maini
first_name: Philip K.
name: Philip K. Maini
affiliations: label: ‡
institution: Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford
country: Kingdom
name: ‡ Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford , Oxford, United Kingdom
last_name: van der Merwe
first_name: P. Anton
name: P. Anton van der Merwe
affiliations: label: †
institution: Sir William Dunn School of Pathology, University of Oxford
country: Kingdom
name: † Sir William Dunn School of Pathology, University of Oxford , Oxford, United Kingdom
orcid: http://orcid.org/0000-0001-5847-5226
last_name: Dushek
first_name: Omer
name: Omer Dushek
corresponding: yes
affiliations: label: †
institution: Sir William Dunn School of Pathology, University of Oxford
country: Kingdom
name: † Sir William Dunn School of Pathology, University of Oxford , Oxford, United Kingdom
label: ‡
institution: Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford
country: Kingdom
name: ‡ Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford , Oxford, United Kingdom
Affiliations: label: †
institution: Sir William Dunn School of Pathology, University of Oxford
country: Kingdom
name: † Sir William Dunn School of Pathology, University of Oxford , Oxford, United Kingdom
label: ‡
institution: Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford
country: Kingdom
name: ‡ Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford , Oxford, United Kingdom
Field: Immunology and Microbiology
Document type: preprint
Year: 2016