Title: Elevated alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality
Authors: orcid: http://orcid.org/0000-0002-8454-9548
last_name: Ritchie
first_name: Scott C.
name: Scott C. Ritchie
corresponding: yes
affiliations: label: 1
institution: Systems Genomics Lab, Baker Heart & Diabetes Institute, Melbourne, Victoria
country: Australia
name: Systems Genomics Lab, Baker Heart & Diabetes Institute, Melbourne, Victoria , Australia
label: 2
institution: Department of Public Health and Primary Care, University of Cambridge
country: United Kingdom
name: Department of Public Health and Primary Care, University of Cambridge , Cambridge CB1 8RN, United Kingdom
label: 3
institution: Department of Clinical Pathology, The University of Melbourne
country: Australia
name: Department of Clinical Pathology, The University of Melbourne , Parkville, VIC 3010, Australia
label: 4
institution: School of BioSciences, The University of Melbourne
country: Australia
name: School of BioSciences, The University of Melbourne , Parkville, VIC 3010, Australia
last_name: Kettunen
first_name: Johannes
name: Johannes Kettunen
affiliations: label: 5
institution: Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu
country: Finland
name: Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu , Oulu 90014, Finland
label: 6
institution: National Institute for Health and Welfare, Helsinki 00271
country: Finland
name: National Institute for Health and Welfare, Helsinki 00271 , Finland
label: 7
institution: NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland
country: Finland
name: NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland , Kuopio 70211, Finland
last_name: Brozynska
first_name: Marta
name: Marta Brozynska
affiliations: label: 1
institution: Systems Genomics Lab, Baker Heart & Diabetes Institute, Melbourne, Victoria
country: Australia
name: Systems Genomics Lab, Baker Heart & Diabetes Institute, Melbourne, Victoria , Australia
label: 2
institution: Department of Public Health and Primary Care, University of Cambridge
country: United Kingdom
name: Department of Public Health and Primary Care, University of Cambridge , Cambridge CB1 8RN, United Kingdom
label: 3
institution: Department of Clinical Pathology, The University of Melbourne
country: Australia
name: Department of Clinical Pathology, The University of Melbourne , Parkville, VIC 3010, Australia
label: 4
institution: School of BioSciences, The University of Melbourne
country: Australia
name: School of BioSciences, The University of Melbourne , Parkville, VIC 3010, Australia
last_name: Nath
first_name: Artika P.
name: Artika P. Nath
affiliations: label: 1
institution: Systems Genomics Lab, Baker Heart & Diabetes Institute, Melbourne, Victoria
country: Australia
name: Systems Genomics Lab, Baker Heart & Diabetes Institute, Melbourne, Victoria , Australia
label: 8
institution: Department of Microbiology and Immunology, The University of Melbourne
country: Australia
name: Department of Microbiology and Immunology, The University of Melbourne , Parkville, VIC 3010, Australia
last_name: Havulinna
first_name: Aki S.
name: Aki S. Havulinna
affiliations: label: 6
institution: National Institute for Health and Welfare, Helsinki 00271
country: Finland
name: National Institute for Health and Welfare, Helsinki 00271 , Finland
label: 9
institution: Institute for Molecular Medicine Finland, University of Helsinki
country: Finland
name: Institute for Molecular Medicine Finland, University of Helsinki , Helsinki 00014, Finland
last_name: Männisto
first_name: Satu
name: Satu Männisto
affiliations: label: 6
institution: National Institute for Health and Welfare, Helsinki 00271
country: Finland
name: National Institute for Health and Welfare, Helsinki 00271 , Finland
last_name: Perola
first_name: Markus
name: Markus Perola
affiliations: label: 6
institution: National Institute for Health and Welfare, Helsinki 00271
country: Finland
name: National Institute for Health and Welfare, Helsinki 00271 , Finland
label: 9
institution: Institute for Molecular Medicine Finland, University of Helsinki
country: Finland
name: Institute for Molecular Medicine Finland, University of Helsinki , Helsinki 00014, Finland
last_name: Salomaa
first_name: Veikko
name: Veikko Salomaa
affiliations: label: 6
institution: National Institute for Health and Welfare, Helsinki 00271
country: Finland
name: National Institute for Health and Welfare, Helsinki 00271 , Finland
last_name: Ala-Korpela
first_name: Mika
name: Mika Ala-Korpela
affiliations: label: 5
institution: Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu
country: Finland
name: Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu , Oulu 90014, Finland
label: 7
institution: NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland
country: Finland
name: NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland , Kuopio 70211, Finland
label: 10
institution: Population Health Science, Bristol Medical School, University of Bristol
country: UK
name: 10 Population Health Science, Bristol Medical School, University of Bristol , Bristol BS8 1TH, UK
label: 11
institution: Medical Research Council Integrative Epidemiology Unit, University of Bristol
country: UK
name: 11 Medical Research Council Integrative Epidemiology Unit, University of Bristol , Bristol BS8 2BN, UK
label: 12
institution: Systems Epidemiology Lab, Baker Heart & Diabetes Institute
country: Australia
name: 12 Systems Epidemiology Lab, Baker Heart & Diabetes Institute , Melbourne, Victoria, Australia
label: 13
institution: Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, The Alfred Hospital, Monash University
country: Australia
name: 13 Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, The Alfred Hospital, Monash University , Melbourne, Victoria, Australia
last_name: Abraham
first_name: Gad
name: Gad Abraham
affiliations: label: 1
institution: Systems Genomics Lab, Baker Heart & Diabetes Institute, Melbourne, Victoria
country: Australia
name: Systems Genomics Lab, Baker Heart & Diabetes Institute, Melbourne, Victoria , Australia
label: 2
institution: Department of Public Health and Primary Care, University of Cambridge
country: United Kingdom
name: Department of Public Health and Primary Care, University of Cambridge , Cambridge CB1 8RN, United Kingdom
label: 3
institution: Department of Clinical Pathology, The University of Melbourne
country: Australia
name: Department of Clinical Pathology, The University of Melbourne , Parkville, VIC 3010, Australia
label: 4
institution: School of BioSciences, The University of Melbourne
country: Australia
name: School of BioSciences, The University of Melbourne , Parkville, VIC 3010, Australia
last_name: Würtz
first_name: Peter
name: Peter Würtz
affiliations: label: 14
institution: Research Programs Unit, Diabetes and Obesity, University of Helsinki
country: Finland
name: 14 Research Programs Unit, Diabetes and Obesity, University of Helsinki , Helsinki, Finland
label: 15
institution: Nightingale Health Ltd
country: Finland
name: 15 Nightingale Health Ltd , Helsinki, Finland
last_name: Inouye
first_name: Michael
name: Michael Inouye
corresponding: yes
affiliations: label: 1
institution: Systems Genomics Lab, Baker Heart & Diabetes Institute, Melbourne, Victoria
country: Australia
name: Systems Genomics Lab, Baker Heart & Diabetes Institute, Melbourne, Victoria , Australia
label: 2
institution: Department of Public Health and Primary Care, University of Cambridge
country: United Kingdom
name: Department of Public Health and Primary Care, University of Cambridge , Cambridge CB1 8RN, United Kingdom
label: 3
institution: Department of Clinical Pathology, The University of Melbourne
country: Australia
name: Department of Clinical Pathology, The University of Melbourne , Parkville, VIC 3010, Australia
label: 4
institution: School of BioSciences, The University of Melbourne
country: Australia
name: School of BioSciences, The University of Melbourne , Parkville, VIC 3010, Australia
Affiliations: label: 1
institution: Systems Genomics Lab, Baker Heart & Diabetes Institute, Melbourne, Victoria
country: Australia
name: Systems Genomics Lab, Baker Heart & Diabetes Institute, Melbourne, Victoria , Australia
label: 2
institution: Department of Public Health and Primary Care, University of Cambridge
country: United Kingdom
name: Department of Public Health and Primary Care, University of Cambridge , Cambridge CB1 8RN, United Kingdom
label: 3
institution: Department of Clinical Pathology, The University of Melbourne
country: Australia
name: Department of Clinical Pathology, The University of Melbourne , Parkville, VIC 3010, Australia
label: 4
institution: School of BioSciences, The University of Melbourne
country: Australia
name: School of BioSciences, The University of Melbourne , Parkville, VIC 3010, Australia
label: 5
institution: Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu
country: Finland
name: Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu , Oulu 90014, Finland
label: 6
institution: National Institute for Health and Welfare, Helsinki 00271
country: Finland
name: National Institute for Health and Welfare, Helsinki 00271 , Finland
label: 7
institution: NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland
country: Finland
name: NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland , Kuopio 70211, Finland
label: 8
institution: Department of Microbiology and Immunology, The University of Melbourne
country: Australia
name: Department of Microbiology and Immunology, The University of Melbourne , Parkville, VIC 3010, Australia
label: 9
institution: Institute for Molecular Medicine Finland, University of Helsinki
country: Finland
name: Institute for Molecular Medicine Finland, University of Helsinki , Helsinki 00014, Finland
label: 10
institution: Population Health Science, Bristol Medical School, University of Bristol
country: UK
name: 10 Population Health Science, Bristol Medical School, University of Bristol , Bristol BS8 1TH, UK
label: 11
institution: Medical Research Council Integrative Epidemiology Unit, University of Bristol
country: UK
name: 11 Medical Research Council Integrative Epidemiology Unit, University of Bristol , Bristol BS8 2BN, UK
label: 12
institution: Systems Epidemiology Lab, Baker Heart & Diabetes Institute
country: Australia
name: 12 Systems Epidemiology Lab, Baker Heart & Diabetes Institute , Melbourne, Victoria, Australia
label: 13
institution: Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, The Alfred Hospital, Monash University
country: Australia
name: 13 Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, The Alfred Hospital, Monash University , Melbourne, Victoria, Australia
label: 14
institution: Research Programs Unit, Diabetes and Obesity, University of Helsinki
country: Finland
name: 14 Research Programs Unit, Diabetes and Obesity, University of Helsinki , Helsinki, Finland
label: 15
institution: Nightingale Health Ltd
country: Finland
name: 15 Nightingale Health Ltd , Helsinki, Finland
Field: Biochemistry, Genetics and Molecular Biology
Document type: preprint
Year: 2018