Title: Deconstruction of the Ras switching cycle through saturation mutagenesis
Authors: orcid: http://orcid.org/0000-0002-9354-3340
last_name: Bandaru
first_name: Pradeep
name: Pradeep Bandaru
affiliations: label: 1
address: Berkeley
institution: Department of Molecular and Cell Biology
country: United States
name: Department of Molecular and Cell Biology , University of California, Berkeley , Berkeley , United States
label: 2
address: Berkeley
institution: California Institute for Quantitative Biosciences
country: United States
name: California Institute for Quantitative Biosciences , University of California, Berkeley , Berkeley , United States
label: 3
address: Berkeley
institution: Howard Hughes Medical Institute, University of California, Berkeley
country: United States
name: Howard Hughes Medical Institute, University of California, Berkeley , Berkeley , United States
orcid: http://orcid.org/0000-0002-1186-0626
last_name: Shah
first_name: Neel H
name: Neel H Shah
affiliations: label: 1
address: Berkeley
institution: Department of Molecular and Cell Biology
country: United States
name: Department of Molecular and Cell Biology , University of California, Berkeley , Berkeley , United States
label: 2
address: Berkeley
institution: California Institute for Quantitative Biosciences
country: United States
name: California Institute for Quantitative Biosciences , University of California, Berkeley , Berkeley , United States
label: 3
address: Berkeley
institution: Howard Hughes Medical Institute, University of California, Berkeley
country: United States
name: Howard Hughes Medical Institute, University of California, Berkeley , Berkeley , United States
last_name: Bhattacharyya
first_name: Moitrayee
name: Moitrayee Bhattacharyya
affiliations: label: 1
address: Berkeley
institution: Department of Molecular and Cell Biology
country: United States
name: Department of Molecular and Cell Biology , University of California, Berkeley , Berkeley , United States
label: 2
address: Berkeley
institution: California Institute for Quantitative Biosciences
country: United States
name: California Institute for Quantitative Biosciences , University of California, Berkeley , Berkeley , United States
label: 3
address: Berkeley
institution: Howard Hughes Medical Institute, University of California, Berkeley
country: United States
name: Howard Hughes Medical Institute, University of California, Berkeley , Berkeley , United States
orcid: http://orcid.org/0000-0003-1467-421X
last_name: Barton
first_name: John P
name: John P Barton
affiliations: label: 4
address: Cambridge
institution: Ragon Institute of MGH, MIT and Harvard
country: United States
name: Ragon Institute of MGH, MIT and Harvard , Cambridge , United States
label: 5
address: Cambridge
institution: Department of Chemical Engineering
country: United States
name: Department of Chemical Engineering , Massachusetts Institute of Technology , Cambridge , United States
label: 6
address: Cambridge
institution: Department of Physics
country: United States
name: Department of Physics , Massachusetts Institute of Technology , Cambridge , United States
label: 7
address: Cambridge
institution: Institute for Medical Engineering and Science
country: United States
name: Institute for Medical Engineering and Science , Massachusetts Institute of Technology , Cambridge , United States
last_name: Kondo
first_name: Yasushi
name: Yasushi Kondo
affiliations: label: 1
address: Berkeley
institution: Department of Molecular and Cell Biology
country: United States
name: Department of Molecular and Cell Biology , University of California, Berkeley , Berkeley , United States
label: 2
address: Berkeley
institution: California Institute for Quantitative Biosciences
country: United States
name: California Institute for Quantitative Biosciences , University of California, Berkeley , Berkeley , United States
label: 3
address: Berkeley
institution: Howard Hughes Medical Institute, University of California, Berkeley
country: United States
name: Howard Hughes Medical Institute, University of California, Berkeley , Berkeley , United States
last_name: Cofsky
first_name: Joshua C
name: Joshua C Cofsky
affiliations: label: 1
address: Berkeley
institution: Department of Molecular and Cell Biology
country: United States
name: Department of Molecular and Cell Biology , University of California, Berkeley , Berkeley , United States
label: 2
address: Berkeley
institution: California Institute for Quantitative Biosciences
country: United States
name: California Institute for Quantitative Biosciences , University of California, Berkeley , Berkeley , United States
label: 3
address: Berkeley
institution: Howard Hughes Medical Institute, University of California, Berkeley
country: United States
name: Howard Hughes Medical Institute, University of California, Berkeley , Berkeley , United States
orcid: http://orcid.org/0000-0002-2632-6418
last_name: Gee
first_name: Christine L
name: Christine L Gee
affiliations: label: 1
address: Berkeley
institution: Department of Molecular and Cell Biology
country: United States
name: Department of Molecular and Cell Biology , University of California, Berkeley , Berkeley , United States
label: 2
address: Berkeley
institution: California Institute for Quantitative Biosciences
country: United States
name: California Institute for Quantitative Biosciences , University of California, Berkeley , Berkeley , United States
label: 3
address: Berkeley
institution: Howard Hughes Medical Institute, University of California, Berkeley
country: United States
name: Howard Hughes Medical Institute, University of California, Berkeley , Berkeley , United States
last_name: Chakraborty
first_name: Arup K
name: Arup K Chakraborty
affiliations: label: 4
address: Cambridge
institution: Ragon Institute of MGH, MIT and Harvard
country: United States
name: Ragon Institute of MGH, MIT and Harvard , Cambridge , United States
label: 5
address: Cambridge
institution: Department of Chemical Engineering
country: United States
name: Department of Chemical Engineering , Massachusetts Institute of Technology , Cambridge , United States
label: 6
address: Cambridge
institution: Department of Physics
country: United States
name: Department of Physics , Massachusetts Institute of Technology , Cambridge , United States
label: 7
address: Cambridge
institution: Institute for Medical Engineering and Science
country: United States
name: Institute for Medical Engineering and Science , Massachusetts Institute of Technology , Cambridge , United States
label: 8
address: Cambridge
institution: Department of Chemistry
country: United States
name: Department of Chemistry , Massachusetts Institute of Technology , Cambridge , United States
label: 9
address: Cambridge
institution: Department of Biological Engineering
country: United States
name: Department of Biological Engineering , Massachusetts Institute of Technology , Cambridge , United States
last_name: Kortemme
first_name: Tanja
name: Tanja Kortemme
affiliations: label: 10
address: San Francisco
institution: Department of Bioengineering and Therapeutic Sciences, California Institute for Quantitative Biomedical Research
country: United States
name: 10 Department of Bioengineering and Therapeutic Sciences, California Institute for Quantitative Biomedical Research , University of California, San Francisco , San Francisco , United States
last_name: Ranganathan
first_name: Rama
name: Rama Ranganathan
corresponding: yes
affiliations: label: 11
address: Dallas
institution: Department of Pharmacology
country: United States
name: 11 Department of Pharmacology , University of Texas Southwestern Medical Center , Dallas , United States
label: 12
address: Dallas
institution: Green Center for Systems Biology
country: United States
name: 12 Green Center for Systems Biology , University of Texas Southwestern Medical Center , Dallas , United States
label: 13
address: Dallas
institution: Department of Biophysics
country: United States
name: 13 Department of Biophysics , University of Texas Southwestern Medical Center , Dallas , United States
orcid: http://orcid.org/0000-0002-4414-5477
last_name: Kuriyan
first_name: John
name: John Kuriyan
corresponding: yes
affiliations: label: 1
address: Berkeley
institution: Department of Molecular and Cell Biology
country: United States
name: Department of Molecular and Cell Biology , University of California, Berkeley , Berkeley , United States
label: 2
address: Berkeley
institution: California Institute for Quantitative Biosciences
country: United States
name: California Institute for Quantitative Biosciences , University of California, Berkeley , Berkeley , United States
label: 3
address: Berkeley
institution: Howard Hughes Medical Institute, University of California, Berkeley
country: United States
name: Howard Hughes Medical Institute, University of California, Berkeley , Berkeley , United States
label: 14
address: Berkeley
institution: Molecular Biophysics and Integrated Bioimaging Division
country: United States
name: 14 Molecular Biophysics and Integrated Bioimaging Division , Lawrence Berkeley National Laboratory , Berkeley , United States
Affiliations: label: 1
address: Berkeley
institution: Department of Molecular and Cell Biology
country: United States
name: Department of Molecular and Cell Biology , University of California, Berkeley , Berkeley , United States
label: 2
address: Berkeley
institution: California Institute for Quantitative Biosciences
country: United States
name: California Institute for Quantitative Biosciences , University of California, Berkeley , Berkeley , United States
label: 3
address: Berkeley
institution: Howard Hughes Medical Institute, University of California, Berkeley
country: United States
name: Howard Hughes Medical Institute, University of California, Berkeley , Berkeley , United States
label: 4
address: Cambridge
institution: Ragon Institute of MGH, MIT and Harvard
country: United States
name: Ragon Institute of MGH, MIT and Harvard , Cambridge , United States
label: 5
address: Cambridge
institution: Department of Chemical Engineering
country: United States
name: Department of Chemical Engineering , Massachusetts Institute of Technology , Cambridge , United States
label: 6
address: Cambridge
institution: Department of Physics
country: United States
name: Department of Physics , Massachusetts Institute of Technology , Cambridge , United States
label: 7
address: Cambridge
institution: Institute for Medical Engineering and Science
country: United States
name: Institute for Medical Engineering and Science , Massachusetts Institute of Technology , Cambridge , United States
label: 8
address: Cambridge
institution: Department of Chemistry
country: United States
name: Department of Chemistry , Massachusetts Institute of Technology , Cambridge , United States
label: 9
address: Cambridge
institution: Department of Biological Engineering
country: United States
name: Department of Biological Engineering , Massachusetts Institute of Technology , Cambridge , United States
label: 10
address: San Francisco
institution: Department of Bioengineering and Therapeutic Sciences, California Institute for Quantitative Biomedical Research
country: United States
name: 10 Department of Bioengineering and Therapeutic Sciences, California Institute for Quantitative Biomedical Research , University of California, San Francisco , San Francisco , United States
label: 11
address: Dallas
institution: Department of Pharmacology
country: United States
name: 11 Department of Pharmacology , University of Texas Southwestern Medical Center , Dallas , United States
label: 12
address: Dallas
institution: Green Center for Systems Biology
country: United States
name: 12 Green Center for Systems Biology , University of Texas Southwestern Medical Center , Dallas , United States
label: 13
address: Dallas
institution: Department of Biophysics
country: United States
name: 13 Department of Biophysics , University of Texas Southwestern Medical Center , Dallas , United States
label: 14
address: Berkeley
institution: Molecular Biophysics and Integrated Bioimaging Division
country: United States
name: 14 Molecular Biophysics and Integrated Bioimaging Division , Lawrence Berkeley National Laboratory , Berkeley , United States
institution: Barcelona Supercomputing Center - BSC
country: Spain
name: Barcelona Supercomputing Center - BSC , Spain
institution: Barcelona Supercomputing Center - BSC
country: Spain
name: Barcelona Supercomputing Center - BSC , Spain
Field: Biochemistry, Genetics and Molecular Biology
Document type: article
Year: 2017