Title: Flex ddG: Rosetta ensemble-based estimation of changes in protein-protein binding affinity upon mutation
Authors: orcid: http://orcid.org/0000-0002-9787-0066
last_name: Barlow
first_name: Kyle A.
name: Kyle A. Barlow
affiliations: label: †
institution: Graduate Program in Bioinformatics, University of California San Francisco
country: United States of America
name: † Graduate Program in Bioinformatics, University of California San Francisco , San Francisco, California, United States of America
last_name: Conchúir
first_name: Shane O
name: Shane O Conchúir
affiliations: label: ‡
institution: California Institute for Quantitative Biosciences, University of California San Francisco
country: United States of America
name: ‡ California Institute for Quantitative Biosciences, University of California San Francisco , San Francisco, California, United States of America
label: ¶
institution: Department of Bioengineering and Therapeutic Sciences, University of California San Francisco
country: United States of America
name: ¶ Department of Bioengineering and Therapeutic Sciences, University of California San Francisco , San Francisco, California, United States of America
last_name: Thompson
first_name: Samuel
name: Samuel Thompson
affiliations: label: §
institution: Graduate Program in Biophysics, University of California San Francisco
country: United States of America
name: § Graduate Program in Biophysics, University of California San Francisco , San Francisco, California, United States of America
last_name: Suresh
first_name: Pooja
name: Pooja Suresh
affiliations: label: §
institution: Graduate Program in Biophysics, University of California San Francisco
country: United States of America
name: § Graduate Program in Biophysics, University of California San Francisco , San Francisco, California, United States of America
last_name: Lucas
first_name: James E.
name: James E. Lucas
affiliations: label: ║
institution: Graduate Program in Bioengineering, University of California San Francisco
country: United States of America
name: ║ Graduate Program in Bioengineering, University of California San Francisco , San Francisco, California, United States of America
last_name: Heinonen
first_name: Markus
name: Markus Heinonen
affiliations: label: ⊥
institution: Aalto University, Department of Computer Science
country: Finland
name: ⊥ Aalto University, Department of Computer Science , Espoo, Finland
label: #
institution: Helsinki Institute for Information Technology HIIT
country: Finland
name: # Helsinki Institute for Information Technology HIIT , Helsinki, Finland
orcid: http://orcid.org/0000-0002-8494-680X
last_name: Kortemme
first_name: Tanja
name: Tanja Kortemme
affiliations: label: ‡
institution: California Institute for Quantitative Biosciences, University of California San Francisco
country: United States of America
name: ‡ California Institute for Quantitative Biosciences, University of California San Francisco , San Francisco, California, United States of America
label: ¶
institution: Department of Bioengineering and Therapeutic Sciences, University of California San Francisco
country: United States of America
name: ¶ Department of Bioengineering and Therapeutic Sciences, University of California San Francisco , San Francisco, California, United States of America
label: †
institution: Graduate Program in Bioinformatics, University of California San Francisco
country: United States of America
name: † Graduate Program in Bioinformatics, University of California San Francisco , San Francisco, California, United States of America
label: §
institution: Graduate Program in Biophysics, University of California San Francisco
country: United States of America
name: § Graduate Program in Biophysics, University of California San Francisco , San Francisco, California, United States of America
label: ║
institution: Graduate Program in Bioengineering, University of California San Francisco
country: United States of America
name: ║ Graduate Program in Bioengineering, University of California San Francisco , San Francisco, California, United States of America
label: @
institution: Chan Zuckerberg Biohub
name: @ Chan Zuckerberg Biohub , San Francisco, CA 9Ą158
notes: E-mail: kortemme@cgl.ucsf.edu
Affiliations: label: †
institution: Graduate Program in Bioinformatics, University of California San Francisco
country: United States of America
name: † Graduate Program in Bioinformatics, University of California San Francisco , San Francisco, California, United States of America
label: ‡
institution: California Institute for Quantitative Biosciences, University of California San Francisco
country: United States of America
name: ‡ California Institute for Quantitative Biosciences, University of California San Francisco , San Francisco, California, United States of America
label: ¶
institution: Department of Bioengineering and Therapeutic Sciences, University of California San Francisco
country: United States of America
name: ¶ Department of Bioengineering and Therapeutic Sciences, University of California San Francisco , San Francisco, California, United States of America
label: §
institution: Graduate Program in Biophysics, University of California San Francisco
country: United States of America
name: § Graduate Program in Biophysics, University of California San Francisco , San Francisco, California, United States of America
label: ║
institution: Graduate Program in Bioengineering, University of California San Francisco
country: United States of America
name: ║ Graduate Program in Bioengineering, University of California San Francisco , San Francisco, California, United States of America
label: ⊥
institution: Aalto University, Department of Computer Science
country: Finland
name: ⊥ Aalto University, Department of Computer Science , Espoo, Finland
label: #
institution: Helsinki Institute for Information Technology HIIT
country: Finland
name: # Helsinki Institute for Information Technology HIIT , Helsinki, Finland
label: @
institution: Chan Zuckerberg Biohub
name: @ Chan Zuckerberg Biohub , San Francisco, CA 9Ą158
Field: Biochemistry, Genetics and Molecular Biology
Document type: preprint
Year: 2017