Title: Hypomorphic mutation of the mouse Huntington’s disease gene orthologue
Authors: last_name: Murthy
first_name: Vidya
name: Vidya Murthy
affiliations: label: 1
institution: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital
country: USA
name: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital , Boston, MA, 02214, USA
notes: These authors contributed equally to this work.
orcid: http://orcid.org/0000-0002-0625-1631
last_name: Tebaldi
first_name: Toma
name: Toma Tebaldi
affiliations: label: 2
institution: Laboratory of Translational Genomics, Centre for Integrative Biology (CIBIO), University of Trento
country: Italy
name: Laboratory of Translational Genomics, Centre for Integrative Biology (CIBIO), University of Trento , Trento, 38123, Italy
label: 3
institution: Yale Cancer Center, Yale University School of Medicine
country: USA
name: Yale Cancer Center, Yale University School of Medicine , New Haven, CT 06520, USA
notes: These authors contributed equally to this work.
orcid: http://orcid.org/0000-0001-7080-6913
last_name: Yoshida
first_name: Toshimi
name: Toshimi Yoshida
affiliations: label: 4
institution: Cutaneous Biology Research Center (CBRC), Mass General Hospital, Harvard Medical School
country: USA
name: Cutaneous Biology Research Center (CBRC), Mass General Hospital, Harvard Medical School , Charlestown, MA, 02129, USA
last_name: Erdin
first_name: Serkan
name: Serkan Erdin
affiliations: label: 1
institution: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital
country: USA
name: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital , Boston, MA, 02214, USA
last_name: Calzonetti
first_name: Teresa
name: Teresa Calzonetti
affiliations: label: 1
institution: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital
country: USA
name: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital , Boston, MA, 02214, USA
label: 5
institution: Frederick Community College
country: USA
name: Frederick Community College , Frederick MD 21701, USA
last_name: Vijayvargia
first_name: Ravi
name: Ravi Vijayvargia
affiliations: label: 1
institution: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital
country: USA
name: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital , Boston, MA, 02214, USA
label: 6
institution: Department of Biochemistry, The Maharaja Sayajirao University of Baroda
country: India
name: Department of Biochemistry, The Maharaja Sayajirao University of Baroda , Sayajigunj, Vadodara, Gujarat 390002, India
last_name: Tripathi
first_name: Takshashila
name: Takshashila Tripathi
affiliations: label: 7
institution: NeuroEpigenetics Laboratory, Centre for Integrative Biology (CIBIO), University of Trento
country: Italy
name: NeuroEpigenetics Laboratory, Centre for Integrative Biology (CIBIO), University of Trento , Trento, 38123, Italy
orcid: http://orcid.org/0000-0002-2243-629X
last_name: Kerschbamer
first_name: Emanuela
name: Emanuela Kerschbamer
affiliations: label: 7
institution: NeuroEpigenetics Laboratory, Centre for Integrative Biology (CIBIO), University of Trento
country: Italy
name: NeuroEpigenetics Laboratory, Centre for Integrative Biology (CIBIO), University of Trento , Trento, 38123, Italy
last_name: Seong
first_name: Ihn Sik
name: Ihn Sik Seong
affiliations: label: 1
institution: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital
country: USA
name: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital , Boston, MA, 02214, USA
last_name: Quattrone
first_name: Alessandro
name: Alessandro Quattrone
affiliations: label: 2
institution: Laboratory of Translational Genomics, Centre for Integrative Biology (CIBIO), University of Trento
country: Italy
name: Laboratory of Translational Genomics, Centre for Integrative Biology (CIBIO), University of Trento , Trento, 38123, Italy
last_name: Talkowski
first_name: Michael E.
name: Michael E. Talkowski
affiliations: label: 1
institution: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital
country: USA
name: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital , Boston, MA, 02214, USA
label: 8
institution: Broad Institute of Harvard and MIT
country: USA
name: Broad Institute of Harvard and MIT , Cambridge, MA 02142, USA
label: 9
institution: Department of Neurology, Harvard Medical School
country: USA
name: Department of Neurology, Harvard Medical School , Boston, MA 02115, USA
orcid: http://orcid.org/0000-0003-0681-9263
last_name: Gusella
first_name: James F.
name: James F. Gusella
affiliations: label: 1
institution: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital
country: USA
name: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital , Boston, MA, 02214, USA
label: 8
institution: Broad Institute of Harvard and MIT
country: USA
name: Broad Institute of Harvard and MIT , Cambridge, MA 02142, USA
label: 10
institution: Department of Genetics, Harvard Medical School
country: USA
name: 10 Department of Genetics, Harvard Medical School , Boston, MA 02115, USA
last_name: Georgopoulos
first_name: Katia
name: Katia Georgopoulos
affiliations: label: 4
institution: Cutaneous Biology Research Center (CBRC), Mass General Hospital, Harvard Medical School
country: USA
name: Cutaneous Biology Research Center (CBRC), Mass General Hospital, Harvard Medical School , Charlestown, MA, 02129, USA
last_name: MacDonald
first_name: Marcy E.
name: Marcy E. MacDonald
affiliations: label: 1
institution: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital
country: USA
name: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital , Boston, MA, 02214, USA
label: 8
institution: Broad Institute of Harvard and MIT
country: USA
name: Broad Institute of Harvard and MIT , Cambridge, MA 02142, USA
label: 9
institution: Department of Neurology, Harvard Medical School
country: USA
name: Department of Neurology, Harvard Medical School , Boston, MA 02115, USA
orcid: http://orcid.org/0000-0001-8295-8025
last_name: Biagioli
first_name: Marta
name: Marta Biagioli
corresponding: yes
affiliations: label: 1
institution: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital
country: USA
name: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital , Boston, MA, 02214, USA
label: 7
institution: NeuroEpigenetics Laboratory, Centre for Integrative Biology (CIBIO), University of Trento
country: Italy
name: NeuroEpigenetics Laboratory, Centre for Integrative Biology (CIBIO), University of Trento , Trento, 38123, Italy
Affiliations: label: 1
institution: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital
country: USA
name: Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital , Boston, MA, 02214, USA
label: 2
institution: Laboratory of Translational Genomics, Centre for Integrative Biology (CIBIO), University of Trento
country: Italy
name: Laboratory of Translational Genomics, Centre for Integrative Biology (CIBIO), University of Trento , Trento, 38123, Italy
label: 3
institution: Yale Cancer Center, Yale University School of Medicine
country: USA
name: Yale Cancer Center, Yale University School of Medicine , New Haven, CT 06520, USA
label: 4
institution: Cutaneous Biology Research Center (CBRC), Mass General Hospital, Harvard Medical School
country: USA
name: Cutaneous Biology Research Center (CBRC), Mass General Hospital, Harvard Medical School , Charlestown, MA, 02129, USA
label: 5
institution: Frederick Community College
country: USA
name: Frederick Community College , Frederick MD 21701, USA
label: 6
institution: Department of Biochemistry, The Maharaja Sayajirao University of Baroda
country: India
name: Department of Biochemistry, The Maharaja Sayajirao University of Baroda , Sayajigunj, Vadodara, Gujarat 390002, India
label: 7
institution: NeuroEpigenetics Laboratory, Centre for Integrative Biology (CIBIO), University of Trento
country: Italy
name: NeuroEpigenetics Laboratory, Centre for Integrative Biology (CIBIO), University of Trento , Trento, 38123, Italy
label: 8
institution: Broad Institute of Harvard and MIT
country: USA
name: Broad Institute of Harvard and MIT , Cambridge, MA 02142, USA
label: 9
institution: Department of Neurology, Harvard Medical School
country: USA
name: Department of Neurology, Harvard Medical School , Boston, MA 02115, USA
label: 10
institution: Department of Genetics, Harvard Medical School
country: USA
name: 10 Department of Genetics, Harvard Medical School , Boston, MA 02115, USA
Field: Neuroscience
Document type: preprint
Year: 2018