How should I think about ways to arrange a desk in a home office
There are several ways to arrange a desk in a home office. A few guiding principles (based on the space and how you'll use your desk) can help guide you along the way. 

* If you're frequently on camera for video calls you'll want to consider what people will see in your background. Avoid clutter and too much distraction, but also feel free to use that part of the office to express yourself professionally. An interesting painting or a few professional accolades can be a good conversation starters.

* Bright windows can be great for creativity but having these directly behind you when on video calls can give you a whitewashed look that's not ideal. Ideally, a window would be in front of you to not only cast your face in a good light, but also to give you a nice view as you work. If you can't position a window on front of your desk, you could always invest in good artificial lighting (e.g., a ring light) to help with video calls. 

* Avoid having positioning your desk so your back is directly in front of the office entrance. If you have line of site to all entrances / exits you'll likely feel more in control while working, which can make you more productive. 

* Position your desk so you have easy access to everything you'd need for work. Frequently used reference materials, papers, writing supplies, etc. should all be within arms length so as not to disrupt your "flow" while working.