Born in Scranton, Pennsylvania, Biden moved with his family to Delaware in 1953. He studied at the University of Delaware before earning his law degree from Syracuse University. He was elected to the New Castle County Council in 1970 and became the sixth-youngest senator in U.S. history after he was elected in 1972, at age 29. Biden was the chair or ranking member of the Senate Foreign Relations Committee for 12 years. He chaired the Senate Judiciary Committee from 1987 to 1995; drafted and led the effort to pass the Violent Crime Control and Law Enforcement Act and the Violence Against Women Act; and oversaw six U.S. Supreme Court confirmation hearings, including the contentious hearings for Robert Bork and Clarence Thomas. Biden ran unsuccessfully for the Democratic presidential nomination in 1988 and 2008. Barack Obama chose Biden as his running mate in the 2008 and 2012 presidential elections. Biden was a close counselor to Obama during his two terms as Obama's vice president. Biden and his running mate, Kamala Harris, defeated incumbents Donald Trump and Mike Pence in the 2020 presidential election. On January 20, 2021, he became the oldest president in U.S. history, the first to have a female vice president, and the first from Delaware. 
https://en.wikipedia.org/wiki/Joe_Biden
Based on this paragraph, how many times has Joe Biden run for president and what characteristics make him unique among all past presidents?
Based on this paragraph, Joe Biden has run for president three times, losing in 1988 and 2008 and eventually winning in 2020. As president, he is unique in three ways: the first to have a female vice president, and the first president from the state of Delaware.