In the season-opener against the Philadelphia Eagles, Goff threw for 215 yards and two touchdowns, but threw an interception returned for a touchdown as the Lions narrowly lost by a score of 38–35. In the next game against the Washington Commanders, he threw for 256 yards and four touchdowns in a 36–27 victory. In the Week 2 game against Washington, Goff produced his sixth straight home game with two or more passing touchdowns, establishing a Lions franchise record. On October 2, Goff again threw four touchdowns passes, and this time added a tenure-high 378 passing yards during a 48–45 loss to the Seattle Seahawks. Goff finished his second season with the Lions with 4,438 yards, 29 touchdowns, and seven interceptions, starting in all 17 games. Goff was named to his third Pro Bowl as an alternative, replacing Super Bowl bound Jalen Hurts.
What was Goff's best game mentioned in the text?
Goff's best game mentioned in the text was on October 2 when he threw four touchdowns passes, and added a tenure-high 378 passing yards during a 48–45 loss to the Seattle Seahawks.

Goff played another good game against the Washington Commanders, when he threw for 256 yards and four touchdowns in a 36–27 victory, but this performance wasn't as good as the game against the Seahawks because he threw for fewer yards even though he threw for the same amount of touchdowns.

Note that the text is also missing information that would be useful in judging Goff's performance such as QBR, completion percentage, etc.