A number of significant inventions and discoveries have been made by Berkeley faculty members and researchers:

Natural sciences
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Atomic bomb – Physics professor J. Robert Oppenheimer was wartime director of Los Alamos National Laboratory and the Manhattan Project.
Carbon 14 and photosynthesis – Martin Kamen and Sam Ruben first discovered carbon 14 in 1940, and Nobel laureate Melvin Calvin and his colleagues used carbon 14 as a molecular tracer to reveal the carbon assimilation path in photosynthesis, known as Calvin cycle.
Carcinogens – Identified chemicals that damage DNA. The Ames test was described in a series of papers in 1973 by Bruce Ames and his group at the university.
Chemical elements – 16 elements have been discovered at Berkeley (technetium, astatine, neptunium, plutonium, americium, curium, berkelium, californium, einsteinium, fermium, mendelevium, nobelium, lawrencium, rutherfordium, dubnium, and seaborgium).
Covalent bond – Gilbert N. Lewis in 1916 described the sharing of electron pairs between atoms, and invented the Lewis notation to describe the mechanisms.
CRISPR gene editing – Nobel laureate Jennifer Doudna discovers a precise and inexpensive way for manipulating DNA in human cells.
Cyclotron – Ernest O. Lawrence created a particle accelerator in 1934, and was awarded the Nobel Physics Prize in 1939.
Dark energy – Saul Perlmutter and many others in the Supernova Cosmology Project discover the universe is expanding because of dark energy 1998.
Flu vaccine – Wendell M. Stanley and colleagues discovered the vaccine in the 1940s.
Hydrogen bomb – Edward Teller, the father of hydrogen bomb, was a professor at Berkeley and a researcher at the Lawrence Livermore National Laboratory and the Los Alamos National Laboratory.
Immunotherapy of cancer – James P. Allison discovers and develops monoclonal antibody therapy that uses the immune system to combat cancer 1992–1995.
Molecular clock – Allan Wilson discovery in 1967.
Neuroplasticity – Marian Diamond discovers structural, biochemical, and synaptic changes in brain caused by environmental enrichment 1964
Oncogene – Peter Duesberg discovers first cancer causing gene in a virus 1970s.
Telomerase – Elizabeth H. Blackburn, Carol Greider, and Jack Szostak discover enzyme that promotes cell division and growth 1985.
Vitamin E – Gladys Anderson Emerson isolates Vitamin E in a pure form in 1952.
What are the major innovations and scientific discoveries from UC Berkeley?
Atomic bomb by J. Robert Oppenheimer, carbon 14 and its photosynthesis, covalent bond, cyclotron, and etc.