page_title: Rapid plasma reagin
hierarchical_section_title: Rapid plasma reagin
caption_attribution_description: Čeština: Elektronový mikroskop: kultura treponem na králičích epitelových buňkách Deutsch: Kultur von Treponema pallidum English: Electron micrograph of Treponema pallidum on cultures of cotton-tail rabbit epithelium cells (Sf1Ep). Treponema pallidum is the causative agent of syphilis. In the United States, over 35,600 cases of syphilis were reported by health officials in 1999. Español: Treponema pallidum. Suomi: Treponema pallidum-bakteeri. Français&#160;: Treponema pallidum est une eubactérie spirochète responsable de la syphilis. Magyar: Treponema pallidum, a szifilisz kórokozója. 日本語: 梅毒トレポネーマ. Simple English: Thats what a culture of the bacteria that cause syphilis look like.
context_page_description: The rapid plasma reagin test is a type of rapid diagnostic test that looks for non-specific antibodies in the blood of the patient that may indicate an infection by syphilis or related non-venereal treponematoses. It is one of several nontreponemal tests for syphilis. The term reagin means that this test does not look for antibodies against the bacterium itself, Treponema pallidum, but rather for antibodies against substances released by cells when they are damaged by T. pallidum. Traditionally, syphilis serologic testing has been performed using a nontreponemal test such as the RPR or VDRL test, with positive results then confirmed using a specific treponemal test such as TPPA or FTA-ABS. This algorithm is currently endorsed by the U.S. Centers for Disease Control and Prevention. In addition to screening for syphilis, a titer can be used to track the progress of the disease over time and its response to therapy.
  The traditional algorithm using a NTT followed by a TT remains the standard in many parts of the world.
context_section_description: The rapid plasma reagin test (RPR test or RPR titer) is a type of rapid diagnostic test that looks for non-specific antibodies in the blood of the patient that may indicate an infection by syphilis or related non-venereal treponematoses. It is one of several nontreponemal tests for syphilis (along with the Wassermann test and the VDRL test). The term reagin means that this test does not look for antibodies against the bacterium itself, Treponema pallidum, but rather for antibodies against substances released by cells when they are damaged by T. pallidum (cardiolipin and lecithin). Traditionally, syphilis serologic testing has been performed using a nontreponemal test (NTT) such as the RPR or VDRL test, with positive results then confirmed using a specific treponemal test (TT) such as TPPA or FTA-ABS. This algorithm is currently endorsed by the U.S. Centers for Disease Control and Prevention (CDC). In addition to screening for syphilis, a titer can be used to track the progress of the disease over time and its response to therapy.
  The traditional algorithm using a NTT followed by a TT remains the standard in many parts of the world.
caption: Treponema pallidum, the bacterium that causes syphilis.
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