page_title: Leukocyte extravasation
hierarchical_section_title: Leukocyte extravasation
context_page_description: Leukocyte extravasation is the movement of leukocytes out of the circulatory system and towards the site of tissue damage or infection. This process forms part of the innate immune response, involving the recruitment of non-specific leukocytes. Monocytes also use this process in the absence of infection or tissue damage during their development into macrophages.
context_section_description: Leukocyte extravasation (also commonly known as  leukocyte adhesion cascade or diapedesis – the passage of cells through the intact vessel wall) is the movement of leukocytes out of the circulatory system and towards the site of tissue damage or infection. This process forms part of the innate immune response, involving the recruitment of non-specific leukocytes. Monocytes also use this process in the absence of infection or tissue damage during their development into macrophages.
caption: Neutrophils extravasate from blood vessels to the site of tissue injury or infection during the innate immune response.