page_title: Lipopolysaccharide
section_title: Biosynthesis and transport
hierarchical_section_title: Lipopolysaccharide / Biosynthesis and transport
context_page_description: Lipopolysaccharides, also known as lipoglycans and endotoxins, are large molecules consisting of a lipid and a polysaccharide composed of O-antigen, outer core and inner core joined by a covalent bond; they are found in the outer membrane of Gram-negative bacteria.
  The term lipooligosaccharide is used to refer to a low-molecular-weight form of bacterial lipopolysaccharides.
caption: LPS Final Assembly: O-antigen subunits are translocated across the inner membrane (by Wzx) where they are polymerized (by Wzy, chain length determined by Wzz) and ligated (by WaaL) on to complete Core-Lipid A molecules (which were translocated by MsbA).[14]