page_title: DAHP synthase
section_title: Structure
hierarchical_section_title: DAHP synthase / Structure
caption_attribution_description: English: This image shows the quaternary structure of DAHP synthase. It was created using Pymol.
context_page_description: 3-Deoxy-D-arabinoheptulosonate 7-phosphate synthase is the first enzyme in a series of metabolic reactions known as the shikimate pathway, which is responsible for the biosynthesis of the amino acids phenylalanine, tyrosine, and tryptophan. Since it is the first enzyme in the shikimate pathway, it controls the amount of carbon entering the pathway. Enzyme inhibition is the primary method of regulating the amount of carbon entering the pathway. Forms of this enzyme differ between organisms, but can be considered DAHP synthase based upon the reaction that is catalyzed by this enzyme.
  In enzymology, a DAHP synthase is an enzyme that catalyzes the chemical reaction
  phosphoenolpyruvate + D-erythrose 4-phosphate + H₂O 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate
  The three substrates of this enzyme are phosphoenolpyruvate, D-erythrose 4-phosphate, and H₂O, whereas its two products are 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate and phosphate.
context_section_description: The quaternary structure of DAHP synthase consists of two tightly bound dimers, which means that DAHP synthase is a tetramer.
  To the right is an image of DAHP synthase that shows the quaternary structure of DAHP synthase. This image shows that DAHP synthase consists of two tightly bound dimers. Each of the monomer chains is colored differently.
  Below the first image to the right is an image of DAHP synthase that also shows quaternary structure, however this image is in a cartoon view. This view also shows each of the four monomers colored differently. In addition, this view can also be used to show secondary and tertiary structures. As shown, two of the monomers have beta sheets that interact on one side of the enzyme, while the other two monomers have beta sheets that interact on the opposite side.
caption: This image shows the quaternary structure of DAHP synthase.
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