page_title: Integrase
hierarchical_section_title: Integrase
caption_attribution_description: English: Cartoon representation of the molecular structure of protein registered with 1c1a code. Deutsch: Grafik des Molekularstruktur von jenem Protein, das mit 1c1a code registriert ist. Plattdüütsch: Grafik, de de Molekularstruktur von dat Protein wiest, dat mit’n Kood 1c1a registreert is.
context_page_description: Retroviral integrase is an enzyme produced by a retrovirus that integrates—forms covalent links between—its DNA into that of the host cell it infects. Retroviral INs are not to be confused with phage integrases, such as λ phage integrase, as discussed in site-specific recombination.
  The macromolecular complex of an IN macromolecule bound to the ends of the viral DNA ends has been referred to as the intasome; IN is a key component in this and the retroviral pre-integration complex.
context_section_description: Retroviral integrase (IN) is an enzyme produced by a retrovirus (such as HIV) that integrates—forms covalent links between—its DNA (genetic information) into that of the host cell it infects. Retroviral INs are not to be confused with phage integrases (recombinases), such as λ phage integrase, as discussed in site-specific recombination.
  The macromolecular complex of an IN macromolecule bound to the ends of the viral DNA ends has been referred to as the intasome; IN is a key component in this and the retroviral pre-integration complex.
caption: Crystal structure of the RSV two-domain integrase.
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