page_title: Small Cajal body specific RNA 24
hierarchical_section_title: Small Cajal body specific RNA 24
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context_page_description: Small Cajal body specific RNA 24 is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U6 spliceosomal RNA.
  scaRNAs are a specific class of small nucleolar RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12.
  ACA12 belongs to the H/ACA box class of guide RNAs as it has the predicted hairpin-hinge-hairpin-tail structure, the conserved H/ACA-box motifs and is found associated with GAR1 protein. ACA12 is predicted to guide the pseudouridylation of residue U40 of the spliceosomal U6 snRNA.
context_section_description: Small Cajal body specific RNA 24 (also known as scaRNA24 or ACA12) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U6 spliceosomal RNA.
  scaRNAs are a specific class of small nucleolar RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12.
  ACA12 belongs to the H/ACA box class of guide RNAs as it has the predicted hairpin-hinge-hairpin-tail structure, the conserved H/ACA-box motifs and is found associated with GAR1 protein. ACA12 is predicted to guide the pseudouridylation of residue U40 of the spliceosomal U6 snRNA.
caption: Predicted secondary structure and sequence conservation of SCARNA24
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