page_title: Proteome
section_title: Methods to study the proteome
hierarchical_section_title: Proteome / Methods to study the proteome
caption_attribution_description: English: Color coded proteome map
context_page_description: The proteome is the entire set of proteins that is, or can be, expressed by a genome, cell, tissue, or organism at a certain time. It is the set of expressed proteins in a given type of cell or organism, at a given time, under defined conditions. Proteomics is the study of the proteome.
context_section_description: Analyzing proteins proves to be more difficult than analyzing nucleic acid sequences. While there are only 4 nucleotides that make up DNA, there are at least 20 different amino acids that can make up a protein. Additionally, there is currently no known high throughput technology to make copies of a single protein. Numerous methods are available to study proteins, sets of proteins, or the whole proteome. In fact, proteins are often studied indirectly, e.g. using computational methods and analyses of genomes. Only a few examples are given below.
caption: This image shows a two-dimensional gel with color coded proteins. This is a way to visualize proteins based on their mass and isoelectric point.
exif: {"Image ImageWidth": "1608", "Image ImageLength": "1743", "Image BitsPerSample": "[8, 8, 8]", "Image Compression": "LZW", "Image PhotometricInterpretation": "2", "Image Orientation": "Horizontal (normal)", "Image SamplesPerPixel": "3", "Image XResolution": "96", "Image YResolution": "96", "Image PlanarConfiguration": "1", "Image ResolutionUnit": "Pixels/Inch", "Image Software": "Adobe Photoshop CS2 Windows", "Image DateTime": "2006:06:22 02:30:23", "Image ExifOffset": "252", "Thumbnail Compression": "JPEG (old-style)", "Thumbnail XResolution": "72", "Thumbnail YResolution": "72", "Thumbnail ResolutionUnit": "Pixels/Inch", "Thumbnail JPEGInterchangeFormat": "390", "Thumbnail JPEGInterchangeFormatLength": "10968", "EXIF ColorSpace": "sRGB", "EXIF ExifImageWidth": "454", "EXIF ExifImageLength": "492"}