page_title: TMEM249
section_title: Primary sequence & variants/isoforms
hierarchical_section_title: TMEM249 / Primary sequence & variants/isoforms
caption_attribution_description: The spliceforms and isoforms of TMEM249 provided by NCBI and Softberry.
context_page_description: TMEM249 is a protein that in humans is encoded by the C8orfk29 gene.
context_section_description: The primary sequence found at NCBI and
  Aceview on NCBI predicts there are five spliceforms, with four closely resembling one another and the fifth missing a large 5' intron region.  Softberry reinforces the Aceview data by predicting five exons, which are seen in four of the five spliceforms of Aceview.
  The general structure of the TMEM249 transcript has a large 5' UTR followed by exon 1, then a large intron followed by exon 2, a small intron then exon 3.  The rest of the protein follows exon 3 with a large intron, exon 4 a small intron then exon 5, the 3' UTR.
  The primary transcript contains all five exons and produces a protein that is 235 Amino Acids long.  Transcript 1 and 2 are translated in the 3' to 5' direction while transcripts 3 through 5 are translated in the 5' to 3' direction.  Note that the gene is encoded on the minus strand within the chromosome.
caption: Isoforms and Splice variants of TMEM249 provided by NCBI's Aceview and Softberry.
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