cyrilzakka/clinical-trials huggingface dataset:
Abdominal Muscles Recovery Response to Kinesiotaping in Women With Postnatal Diastasis

This study aims to investigate abdominal muscle recovery in response to KT by using objective method for assessment as digital caliper, and waist circumference. KT technique will include rectus abdominis, internal and external oblique muscles among females after normal vaginal delivery.


Eligibility Criteria:
Inclusion Criteria:

1. Age will range from 25-35 years.
2. All women give birth by normal vaginal delivery.
3. Diastasis recti more than 2.5 cm at any point along linea alba.
4. Body mass index (BMI) less than 30 kg/m2.
5. After the end of Puerperium period i.e. after eight weeks postnatal.

Exclusion Criteria:

1. Women with skin over sensitivity to tape.
2. Women with abdominal skin diseases.
3. Abdominal hernia.
4. Previous cesarean section.
5. Multiple pregnancies more than 3 times.
6. Other abdominal or back operation.
7. Pregnancy related complications such as polyhydramnios, fetal macrostomia, diabetes, and hypertension.
8. Spinal disorders.
9. Lower limbs deformities.
Correlation Analysis Between ETF and Prognosis of Tympanoplasty

The regular opening of the eustachian tube plays an important role in maintaining normal pressure in middle ear cavity, hearing function and preventing the occurrence of middle ear inflammation. The current evaluation of Eustachian tube function mainly depends on the patient's history of auricular distention, occlusion, physical examination (Valsalva), acoustic impedance test. However, these tests can not accurately assess the eustachian tube function, the lack of quantitative analysis of eustachian tube function. Currently, surgical treatment of patients with chronic otitis media is one of the most important treatment methods. However, the current results show that some patients can not reconstruct the gas-containing structure of the middle ear after operation, which brings about the treatment of diseases and the recovery of auditory function Difficulties. Although domestic and foreign scholars believe that eustachian tube function in tympanoplasty in the reconstruction of the middle ear with air cavity plays an important role, but due to the lack of a reliable quantitative evaluation of eustachian tube function, eustachian tube function in the occurrence of chronic otitis media , There is a lack of reliable evidence-based medicine in the assessment of the value of development and prognosis. In recent years, a new eustachian tube function evaluation method - Eustachian tube manometry technique, began a quantitative objective assessment of Eustachian tube function, combined with physical examination and subjective symptom scales to conduct a comprehensive assessment of eustachian tube function . This study wants to evaluate the eustachian tube function preoperatively and postoperatively in patients with chronic otitis media who underwent surgery. Regular postoperative follow-ups were used to understand the importance of eustachian tube function in the prognosis of chronic otitis media surgery , In order to further improve the eustachian tube function and improve the surgical curative effect of chronic otitis media.


Eligibility Criteria:
Inclusion Criteria:

1.18 to 75 years old, gender is not limited; 2.clear diagnosis of chronic otitis media, middle ear cholesteatoma need tympanoplasty patients; 3.Subjects or their legal representatives can understand the purpose of the study, show sufficient compliance with the research protocol, and sign the informed consent form.

Exclusion Criteria:

1. secondary chronic otitis media (after head and neck cancer radiotherapy);
2. ipsilateral ear recurrence after surgical treatment, requiring secondary surgery;
3. two tympanoplasty surgery;
4. typical allergic rhinitis, nasal endoscopy or imaging studies suggest chronic rhinosinusitis, nasal polyps and other short-term eustachian tube function of a greater impact on the disease;
5. poor general health, with severe liver and kidney dysfunction, coagulation disorders, cardiovascular disease, neurological diseases can not tolerate surgery.
Acupuncture Compared With "Sham" Acupuncture for Treatment of Chronic Neck Myofascial Pain

In order to investigate the therapeutic effect of acupuncture on chronic neck myofacial pain syndrome, the investigaotrs designed a pilot study of a single-blind randomized controlled trial. A total of 34 chronic neck myofacial pain syndrome patients were selected from Department of Neurology of Nantou Hospital, Department of Health. The age ranged from 18 to 85, and all subjects were full informed consent and volunteers. They were divided into two groups of 17 subjects randomly as follows: acupuncture group, acupuncture stainless needles were inserted into bilateral Fenhchi, Jianliao and Houxi acupoints, respectively. The acupuncture needles then were manual twist and de Qi, and remain for 20 min; sham acupuncture group, the methods were identical the acupuncture group, but acupuncture stainless needles were inserted into subcutaneous tissue only. All the subjects were treated with acupuncture two times per week and continuously three weeks, i.e. Six times acupuncture treatment. The therapeutic effect of acupuncture was assessed before and finishing six times acupuncture treatment, and four weeks and twelve weeks after stopping acupuncture, respectively. The index of acupuncture therapeutic effect was according to the range of motion (ROM) of the cervical spine, the intensity of pain (Short-Form McGill Pain Questionnaire; SF-MPQ) and quality of life (SF-36). The investigators expect acupuncture apply to bilateral Fenhchi, Jianliao and Houxi acupoints may relief the pain and motion of chronic neck facial pain syndrome patient, and also improves the life quality.


Eligibility Criteria:
Inclusion Criteria:

* 18-85 year-old patients with neck myofascial pain for more than one month; not received any treatment in the two weeks before participating this study

Exclusion Criteria:

* Fracture or surgery of the cervical spine; Cervical radiculopathy or myelopathy; Any rheumatic disorder; Systemic disorders; Major psychiatric disorder, alcoholism or substance abuse; Coagulation dysfunction, or related medicines; Pregnancy; Contraindications to acupuncture; Refused to sign consent
Quality Assurance of Obstetrics and Gynecology Department

This work aimed to prepare the obstetrics and gynecology department for high education and health care accreditation.

For Institutional Capacity and Educational Effectiveness we have used a special questioner for assessment (Met or Not Met Questioner). For Quality Assurance System in Health-care we used a special questioner which contain several items each of them may be A ,B or C. A= structured standards, and are scored as M= Met or N=Not Met or NA=Not Applicable ,The B \&C standards are implementation standards . these standards are scored either on the number of observations , documentation of deficiencies , or non compliance with the standards.

Eligibility Criteria:
Inclusion criteria:

* Female patients attending the obstetrics and gynecology department
* Medical and assistant medical staffs
* institutional employees

Exclusion criteria:

* Female patients complaining from disorders not included in the obstetrics and gynecology department activities.
* Male patients.
A Computer-based Cognitive Remediation Program for Adults With Intellectual Disability

Adults with intellectual disabilities have great difficulty in adapting to social situations and relationships. Cognitive impairment associated with intellectual disability are important factors to understand their difficulties in processing social information. In the field of recognition of facial emotions in particular, basic cognitive processes such as visuospatial and attentional functions, are heavily involved. Cognitive remediation is a management tool widely used by practitioners to help patients who experience cognitive difficulties. Currently, no program can meet specific and validated the problems are adults with intellectual disabilities manner in their daily functioning

Réhabilitus is a remediation program focused on attentional functions and visuospatial, to limit the presence of behavioral disorders among adults with intellectual disabilities. The main objective is to validate the effectiveness of Réhabilitus program on behavioral disorders in adults with intellectual disabilities without autism spectrum disorder associated.

Eligibility Criteria:
Inclusion Criteria:

* Adults aged 18 to 45 inclusive;
* Behavioral disorders corresponding to a total score on the ABC scale \> 15
* Presence of a family caregiver (parent, friend) or professional (reeducator, professional of the medico-social sector) stakeholder of the project;
* Diagnosis of mild to moderate intellectual disability (assessed by WAIS-IV battery and VABS-II less than 3 years ago;
* French or secondary mother tongue;
* Psychoactive treatment unchanged during the month prior to inclusion;
* Adult or legal representative who has given written and informed consent to participate in the study. By default, the adult's oral agreement will be collected (as well as the written consent of the legal representative);
* Affiliation to the social security scheme or beneficiary of such a scheme.

Exclusion Criteria:

* Neurological disorders of vascular, infectious or neurodegenerative origin;
* Taking medications for general medical purposes with a neurological or psychiatric impact (eg corticosteroids);
* Simultaneous participation in any other cognitive remediation program targeting attentional, visuospatial and social cognition;
* Refusal of participation of the person and/or his/her legal representative;
* Not family or professional caregiver;
* Presence of Autistic Spectrum Disorders (evaluated by ADOS and ADI if necessary according to the assessment of the investigator)
Primary Care, Communication, and Improving Children's Health

The purpose of this study is to determine communication content and strategies in primary care that predict improvement in weight status among overweight school-age children.

We will test whether 1) pediatrician-patient communication regarding overweight status, behavior/risk-factor counseling, and the frequency and time to next follow-up visit, compared with either no communication or incomplete communication (communicating only high weight status without behavior/risk-factor counseling or a follow-up visit) will predict improvement in weight status at one year follow-up, and 2) during pediatrician-patient communication regarding weight and weight management, higher patient-centeredness will predict improvement in weight status at one year follow-up. The communication content identified will generate new information about the most effective content and style of pediatrician-patient communication that predict weight-status improvement. Because we prospectively will examine clinical practice elements in the one-year interval between well-child visits, acknowledging that communication regarding high weight status may initiate assessment of risk factors for heart disease (such as high cholesterol and blood sugar), more frequent follow-up visits, or prompt a nutrition referral, we will generate novel information about the most effective clinical practices and follow-up interval and frequency that predict weight-status improvement in overweight children. We also will examine if the content and style of communication are related to improvements in diet and lifestyle behaviors at one-year follow-up.

Eligibility Criteria:
Inclusion Criteria:

* Schedule a well-child visit with a participating pediatrician
* Agree to return in one year for the follow-up well-child visit
* Overweight
* 6-12 years old
* Have a working telephone and/or e-mail address
* Child/parent willing to provide assent/consent

Exclusion Criteria:

* Unstable illness (such as uncontrolled asthma)
* Developmental condition (such as trisomy 21)
* Planning to move/leave practice within two years
Trial Comparing Low Dose and High Dose Steroids in Patients Undergoing Colorectal Surgery

The purpose of this study is to evaluate the effect of low dose versus high dose steroids vital signs of patients currently on steroids or recently treated with steroids undergoing major colorectal surgery. The investigators hypothesize that there will be no statistically significant difference in orthostatic hypotension (blood pressure measured on lying, sitting, and standing), blood pressure, temperature or heart rate in the standard and low dose groups.

Our primary aim is to study the perioperative hemodynamic profile of patients on chronic steroids undergoing colon and rectal surgery. We will do this by measuring heart rate, temperature and blood pressure in the operating room and during their postoperative hospitalization. Patients will be identified in their preoperative visit. They will be randomized to high dose and low dose steroid study groups. The standard dose steroid patients will receive hydrocortisone 100 mg IV preoperatively and 100 mg IV every 8 hrs with standard taper. The low dose steroid study group will receive the IV equivalent of their preoperative steroid dose in the postoperative period. The patients blood pressure, temperature and heart rate will be monitored in the operating room and the ward postoperatively. Outcomes will be compared between the two groups. We hypothesize that there will be no statistically significant difference in blood pressure, temperature or heart rate in the high dose and low dose groups.

The secondary aim of this study will be monitoring of any differences in surgical outcomes, including postoperative length of stay, between the two patient groups.

Eligibility Criteria:
Inclusion Criteria:

* History of ulcerative colitis, inflammatory bowel disease unclassified, indeterminate colitis, or Crohn's disease;
* Major colorectal surgery, defined as surgery requiring an abdominal incision. Both open and laparoscopic procedures are eligible. Urgent and elective procedures are eligible;
* Corticosteroid therapy within 12 months of surgery;
* Able and willing to comply with all protocol procedures for the planned duration of the study
* Able and willing to understand, sign and date an informed consent document, and authorize access to protected health information.

Exclusion Criteria:

* Patients with hypotension (systolic \< 90 mm Hg or diastolic \< 50 mm Hg) in the preoperative area
* Patients having emergency surgery
* Children \< 18 or adults \> 75 years of age
* Pregnant patients
* Patients who have suffered prior hemodynamic complications of steroid withdrawal
* Other major physical or major psychiatric illness, including alcohol or substance addiction, within the last 6 months that in the opinion of the investigator would affect the patient's ability to complete the trial.
* Any condition or situation that, in the opinion of the investigator, would prevent proper evaluation of the safety or efficacy of the different steroid doses according to the study protocol
* Patients on steroids without inflammatory bowel disease
Evaluating the Addition of Hemodiafiltration to EVLP - Impact on the Regeneration of Marginal Donor Lungs

The primary objective of the study is the evaluation of the effect of hemodiafiltration during ex vivo lung perfusion in marginal donor lungs, and its feasibility. The hypothesis of this study is that this therapy could stabilize perfusate electrolyte composition, remove toxins and waste products, normalize pH levels and prevent edema formation, thereby reconditioning marginal donor lungs for transplantation.

The proposed pilot study addresses the unmet clinical needs in several aspects: a) for the first time a homeostatic device will be introduced in EVLP to reach stable perfusate composition; b) the proposed modification of the standard EVLP could lead to longer perfusion times, making elective transplantation possible and setting the base for possible ex vivo lung treatments; c) the ultimate effect of the proposed study is to increase organ availability through reconditioning of marginal donor lungs.


Eligibility Criteria:
Inclusion Criteria:

* Marginal donor lungs according to the ISHLT criteria (18)

  * PaO2/FiO2 ratio \< 400 (with FiO2=1.0 and PEEP=5-8cmH2O)
  * Donor age ≥ 55 years
  * Smoking history ≥ 20 pack-years
  * Infiltrates in chest radiograph
  * Significant secretions in bronchoscopy
  * Organisms on sputum gram stain
* Donor age \> 18 years

Exclusion Criteria:

For donor organs:

* Bilateral consolidations in donor lungs
* Lungs from donors with chest trauma
* Lungs from drowned donors

For patients receiving lung transplantation:

* Inclusions in other interventional studies
* Patients on the intensive care unit (ICU) prior to transplantation, with mechanical ventilation and/or extracorporeal membrane oxygenation (ECMO) support
* Re-transplantations
Bladder Wall Blood Perfusion Pattern and Sexual Dysfunction in Female Patients With Lower Urinary Tract Symptoms, and the Association of That Perfusion Pattern and Therapeutic Efficacy of Antimuscarincs for Female Overactive Bladder Syndrome.

Overactive bladder syndrome (OAB) affects around 17 % of female population. However, the etiology of OAB is complicated and unclear in many aspects. Bladder wall thickness had been reported to be strongly associated with OAB, but its use as a screening tool remains controversial. Besides, few studies reported patterns of sexual dysfunction in female patients with lower urinary tract symptoms (LUTS). Therefore the aims of our study were to analyze the bladder wall blood perfusion pattern in female LUTS patients, the association of between the bladder wall blood perfusion pattern and the efficacy of anti-muscarinic treatment for female OAB, and the patterns of sexual dysfunction in the female LUTS patients.


Eligibility Criteria:
Inclusion Criteria:

* all cases are female patients with lower urinary tract symptoms

Exclusion Criteria:

* nil
Patent Foramen Ovale Closure in Migraine

The goal of this observational study is to retrospectively observe the effect of PFO closure and medication on migraine. The main questions it aims to answer are:

* Whether PFO closure is more effective in the treatment of migraine than traditional medical treatment
* What factors affect the effectiveness of migraine treatment ?

Participants will undergo contrast transthoracic echocardiography to diagnose PFO and evaluate right-to-left shunt. They will be treated with medication and PFO closure respectively according to guidelines. HIT-6 and a questionnaire about migraine were obtained at the baseline and repeated at the 6-month and 12-month follow-up visits.

Researchers will compare closure group and drug group to see efficacy of two groups in treating migraine.

Migraine patients with PFO who were admitted to our hospital from January 2018 to August 2021 were enrolled.They will be treated with medication and PFO closure respectively according to guidelines. Headache impact test (HIT-6) and a questionnaire about migraine were obtained at the baseline and repeated at the 6th and 12th month follow-up visits.

1. HIT-6 was used to assess migraine severity.
2. Questionnaire included questions regarding average duration of migraine, migraine frequency, relief of migraine after treatment, family history and medication use.
3. △HIT-6 is the difference between baseline and follow-up in HIT-6 and is used to assess migraine relief. The days of migraine attacks per month (MAD) were calculated by the product of the frequency of headache attacks and average duration of each attack. Therefore, the days of migraine remission per month (MRD)= MAD at the 6th or 12th month follow-up- MAD at baseline. In comparison with baseline, 50% decrease in the number of total attacks was considered responder.
4. Four parameters were selected to evaluate the treatment effect: HIT-6, △HIT-6, MRD, and response rate.

Eligibility Criteria:
Inclusion Criteria:

Closure group:

* Migraine patients with grade II-III RLS of PFO confirmed by cTTE.
* HIT-6≥50.
* Meeting the surgical indications of PFO closure according to Chinese expert consensus on Prophylactic Closure of Patent foramen ovale published in March 2017
* Patients who have underwent PFO closure.

Drug group:

* Migraine patients with grade II-III RLS of PFO confirmed by cTTE.
* HIT-6 ≥ 50.
* Patients who have underwent drug treatment for 12 months.

Exclusion Criteria:

* Congenital heart diseases, cardiomyopathy, heart failure, valvular heart disease, arrhythmia, severe hypertension or other heart diseases.
* Patients with serious complications after closure.
* Patients who have other known triggers of migraine.
* Patients with incomplete follow-up data.
Sleep, Diet, Exercise and Older Persons

To examine the impacts of a cognitive yoga program and circuit resistance training on cognitive and physical performance with nutrition and sleep as modulating factors in healthy, older adults.


Eligibility Criteria:
Inclusion Criteria:

* Montreal Cognitive Assessment \> 23
* No memory loss complaints

Exclusion Criteria:

* Uncontrolled cardiovascular or neuromuscular disease that prevents participation in a training program
* Musculoskeletal impairments or injury that may impact exercise participation
* Visual or hearing impairments
* Neurological disease
* Stroke
Central Venous Access Study

The aim of this study is to document clinicians variation in practice in comparison to standard guidelines by the Medical Center's approved Evidence-based Practice (EBP) guidelines, policies, and procedures for Central Venous Catheter(CVC), Peripherally Inserted Central Catheter (PICC), and Hemodialysis (HD catheters by way of a structured retrospective review of the Electronic Medical Record (EMR) system.

This will be a single site retrospective (non-experimental) study utilizing the electronic medical record, both descriptive and correlational methods.

There will be two outcomes:

1. The outcomes associated with the management of Central Venous Catheter(CVC), Peripherally Inserted Central Catheter (PICC), and Hemodialysis (HD) Catheter in adherence with hospital approved Evidence-based Practice guidelines for Central Venous Catheter(CVC), Peripherally Inserted Central Catheter (PICC), and Hemodialysis (HD) Catheter.
2. The mechanical/technical, thrombotic, and other adverse outcomes (Heparin induced coagulopathy) associated with central venous catheters due to variation in insertion and management practices of Central Venous Catheter(CVC), Peripherally Inserted Central Catheter (PICC), and Hemodialysis (HD) Catheter.

Eligibility Criteria:
Inclusion Criteria:

• Adult patients in Medical Intensive Care Unit (MICU), Coronary Care Unit (CCU), Cardiac Surgical Intensive Care Unit (CSICU), Surgical Intensive Care Unit (SICU) with either CVCs, PICCs, or HD catheters.

Exclusion Criteria:

• Pediatric (including neonates), obstetric and gynecology, medical-surgical, and oncology patients.