Feasibility of Using Prism Adaptation to Treat Spatial Neglect and Motor Function in Stroke

This research project is a study designed to address both motor and cognitive changes after stroke. Treatment for SN is elusive however there is support for prism adaptation treatment (PAT). Therapists need to know more about the effects of this treatment and if it is feasible in a group of stroke survivors with multiple lesions because these are the patients they are treating in the clinical setting. Also, it has not been investigated that using PAT to remediate SN will then as a result increase spontaneous UE movement of the weak limb.

This research project is a study designed to address both motor and cognitive changes after stroke, two common stroke disabilities. For example: two third of patients reported loss of upper limb function as a major problem after stroke and spatial neglect occurs in more than 350,000 US right hemisphere stroke survivors annually. These two impairments if not treated, lead to immediate impairment in basic life activities, long term functional disability, increased risk for falls and increased healthcare costs. The literature displays many strong research studies that trialed the use of multiple treatment approaches to remediate spatial neglect, including prism adaptation treatment (PAT), resulting in positive results. Similar findings result for treatment studies that attempt to remediate the upper extremity (UE). However, in all group of patients that were tested in these studies (both for spatial neglect and UE dysfunction) only had one stroke and past medical histories that were unremarkable. Rehabilitation professionals help clients that have had all types of strokes achieve improved quality of life by helping to increase independence by remediating impairment. In addition, these professionals need to know more about the effects of PAT in stroke survivors with multiple lesions because these are patients commonly being treated in the clinical setting. Also, it has not been investigated whether using PAT, a very promising and easy to administer treatment, to remediate spatial neglect will also increase spontaneous UE movement of the limb affected by the stroke because of an influence on motor-intentional aiming errors. Thus, in this pilot research proposal, the researcher intends to first investigate the feasibility of this two week treatment on stroke survivors that have had multiple lesions and second verify if PAT will improve spatial neglect and jointly increase spontaneous movement of the UE.

Eligibility Criteria:
Inclusion Criteria:

* Between the ages of 18 and 90.
* New stroke on the right side of the brain.
* Has an UE impairment of the arm affected by the stroke (WMFT score of less than 75).
* Has the presence of spatial neglect (greater than 1 on the KF-NAP).
* Is able to give informed consent.
* Past medical history includes having had a stroke or more than one. This can be ischemic or hemorrhagic, and on either side of the brain.

Exclusion Criteria:

* Is under the age of 18.
* Has severe communication deficit.
* Has a left brain stroke as the primary diagnosis and/or the primary diagnosis is anything other than stroke.
* Is blind in one or both eyes.
* Is not staying at the inpatient rehabilitation hospital
* Has a cognitive impairment that inhibits their ability to recall information.
* Has severely impaired upper extremity function in bilateral arms (cannot participate in the prism task).