Assessment of 3M Oedema Reduction System in the Treatment of Lymphoedema Compared to Commercial Short-stretch Bandage

Objectives. The primary objective of the study is to assess volume reduction in the treatment of lymphoedematous legs and arms with compression bandaging.

Secondary objectives:

* Assessment of safety
* Quality of life
* Health economic parameters
* Slippage
* Subbandage pressure


Eligibility Criteria:
Inclusion Criteria (Arm):

* Mobile males or females, age 18 years or older
* Unilateral arm lymphoedema of secondary origin
* Pitting arm lymphoedema diagnosed as stage II or late stage II according to the International Society of Lymphology staging
* Patients who require intense bandaging therapy (approx. \>= 15% increase in arm volume over the opposite healthy arm)
* Completion of all primary and adjuvant cancer treatments (surgery, chemotherapy, radiotherapy) at least 6 months prior to randomisation
* Willing to give written informed consent and willing to comply with the study protocol

Inclusion Criteria (Leg):

* Mobile males or females, age 18 years or older
* Unilateral or bilateral leg lymphoedema of primary or secondary origin
* Pitting leg lymphoedema diagnosed as stage II or late stage II according to the International Society of Lymphology staging
* Patients who require intense bandaging therapy
* Completion of all primary and adjuvant cancer treatments (surgery, chemotherapy, radiotherapy) at least 6 months prior to randomisation
* Willing to give written informed consent and willing to comply with the study protocol

Exclusion Criteria (Arm):

* Known pregnancy
* Evidence of active cancer, either local or metastatic
* A period of intense daily bandaging within the last month
* Decompensated heart failure or clinically relevant kidney or liver disease
* Known relevant arterial disease of the arms
* Deep vein thrombosis or phlebitis in the last 3 months
* Paralysis of the arms
* Clinical infection of the arms (e.g. erysipelas)
* Wounds located at the study arm that require dressing change more than once a week
* History of allergic reactions to study material
* Participation in any prospective clinical study that can potentially interfere with this study
* Participants who are, in the opinion of the clinical investigator, unsuitable for enrolment in this study, for reasons not specified in the exclusion criteria.

Exclusion Criteria (Leg):

* Known pregnancy
* Evidence of active cancer, either local or metastatic
* A period of intense daily bandaging within the last month
* Decompensated heart failure or clinically relevant kidney or liver disease
* Deep vein thrombosis or phlebitis in the last 3 months
* Known relevant arterial disease of the legs
* Paralysis of the legs
* Clinical infection of the legs (e.g. erysipelas)
* Circumferential Lymphorrhoea
* Wounds located at the study leg that require dressing change more than once a week
* History of allergic reactions to study material
* Participation in any prospective clinical study that can potentially interfere with this study
* Participants who are, in the opinion of the clinical investigator, unsuitable for enrolment in this study, for reasons not specified in the exclusion criteria.