cyrilzakka/clinical-trials huggingface dataset:
The Effect of Yoga on Gaining Sleep Habits in Children

This study was planned to determine the effect of the "Little Yogis Doing Yoga" Program, which will be created within the scope of the research, on getting children aged 5-6 years old to sleep habits. This study was planned in a pretest, posttest design, follow-up, randomized controlled study. The sample of the study will consist of 36 children (18 children in the intervention group, 18 children in the control group) in the 5-6 age group in Antalya between 15 March and 15 June 2023. The "Little Yogis Doing Yoga" Program, which was created within the scope of the research, will be applied to the children in the intervention group in two groups, two days a week, for 4 weeks, 30 minutes each, by the researcher who received child yoga specialization training. Data will be collected with Child and Family Information Form and Child Sleep Habits Questionnaire-CSHQ). CSHQ, T0-Pretest (Before the Program "Little Yogis Doing Yoga"), T1-Interim follow-up (after the program ends) and T2-Posttest (1 month after the program is completed) will be filled by the parents. Statistical Package for the Social Sciences (SPSS) 24.0 package program will be used in the analysis of the data.

Preschool (three-six years) is a period in which the physical, psychomotor, social-emotional, cognitive and language development of the child is completed to a large extent. In this period when the growth-development process is very important, healthy and regular sleep plays an active role in many developmental areas of children, especially in brain development. For this reason, examining and arranging the sleep habits of children in the preschool period is of great importance for the healthy completion of the process. The aim of this study is to determine the sleep habits of children in the 5-6 age group and to determine the effect of children's yoga on these habits. This study was planned to determine the effect of the "Little Yogis Doing Yoga" Program, which will be created within the scope of the research, on instilling sleep habits in children aged 5-6 years.

Eligibility Criteria:
Inclusion Criteria:

* 5-6 years old
* No school attendance problems
* Those who have the cognitive ability to carry out the commands given during child yoga.
* Having no physical problems that may prevent active participation in children's yoga
* Children who do not have an obstacle to communication (sight, hearing problems, etc.) and whose parents' consent to participate in the study are approved

Exclusion Criteria:

* Children who are actively attending any children's yoga program
Characterization of Proliferating Compartment in B-Cell Patients and in Healthy Aging Subjects

By ingesting a non-radioactive and non-toxic compound "heavy water" for 6 weeks, the DNA of newly developed cells in the body of subjects with B-cell chronic lymphocytic leukemia can be labeled and followed by performing routine blood draws at specified time intervals. By using mass spectrometric analysis we can measure how quickly new B-CLL cells are generated in the bone marrow and how quickly they leave the blood, a measure of cell turnover. This will help us to better understand the unique characteristics of this disease process.

By ingesting a non-radioactive and non-toxic compound "heavy water" for 6 weeks, the DNA of newly developed cells in the body of subjects with B-cell chronic lymphocytic leukemia (B-CLL) can be labeled and followed by performing routine blood draws at specified time intervals. By using mass spectrometric analysis we can measure how quickly new B-CLL cells are generated in the bone marrow and how quickly they leave the blood, a measure of cell turnover. This will help us to better understand the unique characteristics of this disease process.

Eligibility Criteria:
Inclusion Criteria:

* 18 years of age,
* Patients must be willing to contribute the required amount of blood without compromising their well being,
* Participants must be willing to be contacted in the future.

Exclusion Criteria:

* Pregnancy,
* Patients who are known to be anemic, with a hemoglobin \< 8,
* Patients who are known to be infected with HIV.
The Effect of Fish Oil Supplementation on Vocal Performance

The purpose of this study was to determine if use of omega-3 PUFA supplement in combination with a singer's training regimen enhances training adaptations and body composition.


Eligibility Criteria:
Inclusion Criteria:

* Apparently healthy college vocal performers (male and female of all ethnicities) \*Between the ages of 18-28 years
* Majoring in classical voice in the Baylor University School of Music or musical theatre in the Baylor University Department of Theatre Arts.

Exclusion Criteria:

* Previously diagnosed with a voice disorder
* Vegans
* Smokers
* Allergic to fish, shellfish or safflower oil
* Have been taking daily FO n-3 supplement within the past three months, or any supplement known to effect muscle biology (e.g. creatine).
Comparison Between Coolprep and Picolyte for Bowel Cleansing

The investigators will compare with PEG+ascorbic acid and picosulfate+magnesium citrate about bowel preparation, patient's satisfaction, side effects to identify effectiveness of new bowel preparation drug.

The investigators can find easily colon cancer and poly by colonoscopy, but bowel preparation is very important to find the lesion. Desirable bowel preparation drug must be clearly removed stool, effective on colonoscopic finding and pathologic finding, quickly administrated agent and eliminated stool, comfort for patient, and less side effects.

PEG is very safe osmotic laxative. New agent(coolprep) which add ascorbic acid is less salty and less volume. Picosulfate+magnesium citrate(picolyte) taste orange, can be easily prepared bowel for colonoscopy by good taste and small volume. Magnesium with citrate acts like osmotic agent, picosulfate acts irritant agent.

The investigators will compare with PEG+ascorbic acid and picosulfate+magnesium citrate about bowel preparation, patient's satisfaction, side effects to identify effectiveness of new bowel preparation drug.

Eligibility Criteria:
Inclusion Criteria:

* Age : over 19 years
* Who will be done colonoscopy
* Who accepted informed consent

Exclusion Criteria:

* Age : over 80 years
* Electrolyte imbalance
* Liver function test abnormality, ascites(over 2 times, \>Child class B)
* ARF or CRF(GFS\<30)
* Recent MI(\< 6months) or Unstable angina pectoris
* Congestive heart failure(NYHA \> 2)
* Inflammatory bowel disease
* Abdominal minor surgery
Assessment of Spread of Transversus Abdominis Plane Block

For the purpose of assessing the spread of the local anaesthetic after injecting it between abdominal muscles on both sides, the investigators will test if the patient can feel a change in the perception of cold and warm, as well as being pricked with a blunt needle. The investigators will also take several blood samples, together with routine samples, to measure the concentration of the local anesthetic in the blood.


Eligibility Criteria:
Inclusion Criteria:

* undergo abdominal surgery, eligible for TAP block, over 18, BMI 20-40

Exclusion Criteria:

* does not speak danish, does not consent, does not fulfill inclusion criteria
The Association Between the Use of Complementary and Alternative Medicine and Medication Adherence in Hypertensive African-Americans

The objective of this study is to better understand strategies used by African Americans with hypertension in order to control their blood pressure.

The objective of this study is to better understand strategies used by African Americans with hypertension in order to control their blood pressure. Through the use of qualitative interviews, the beliefs and attitudes toward complementary medicine of African Americans with hypertension will be elucidated.

Eligibility Criteria:
Inclusion Criteria:

1. Patients will be African-American adults 18 years or older who were diagnosed with poorly controlled hypertension as defined by the 6th Joint National Committee guidelines (systolic \>140 and diastolic \>90).
2. Patients will also be eligible if they are taking any prescribed anti-hypertensive medications.
3. Patients must be able to provide informed consent in English. Participants will be recruited from Cornell Internal Medicine Associates, the primary care and general medicine practice at Cornell Medical Center, the same site as the parent grant.

Exclusion Criteria:

1. Patients who refused to participate.
2. Patients who are unable to provide informed consent.
Retrospective Follow-up of BIOLUX P-I/-II

The aim is to collect long-term clinical data from 132 patients from Belgium, Germany and Austria who had previously participated in either of the BIOLUX P-I or P-II studies. Patients in these studies were treated with either a percutaneous transluminal angioplasty (PTA) balloon catheter or a drug-coated Passe-18-Lux balloon (DCB). The purpose of Retro-BIOLUX P-I-II is to collect clinical data from patients treated with either Passeo-18 PTA or Passeo-18 Lux DCB to analyze the long-term effects.


Eligibility Criteria:
Inclusion Criteria:

1. Subject was previously enrolled in either BIOLUX P-I or BIOLUX P-II
2. Subject was treated either with Passeo-18 PTA or Passeo-18 LUX
3. Written informed consent by subject or subject's legal representative or impartial witness/waiver

Exclusion Criteria:

1. Subject did neither participate in BIOLUX P-I nor BIOLUX P-II
2. Subject was neither treated with Passeo-18 Lux nor with Passeo-18 PTA
3. Subject is not willing to sign an informed consent /data release form
Refraction Determination Analysis

Correlating the accuracy of a refraction done over telemedicine to that of a standard refraction, with a study hypothesis that the results will be equivalent.


Eligibility Criteria:
Inclusion Criteria:

* 18-40 years old
* healthy eyes

Exclusion Criteria:

* mid level ocular diseases (glaucoma, hypertension, retinal issues)
* psychiatric disorders
* brain tumor or history of
* under 18, or over 40 years old
Global collaboRAtion on CIC-DUX4, BCOR-CCN3, High-grade Undifferentiated Round Cell Sarcoma (URCS) Project

Experimental study with biological material : case series review of clinical and histological data

This is a multicenter retrospective and prospective study that will analyze all cases with a diagnosis of Undifferentiated round cell sarcomas from 01 January 1983 and all new cases referring to each participant site.

Eligibility Criteria:
Inclusion Criteria:

* Patients with undifferentiated round cell sarcomas treated from 01 January 1983 and all new patients will be included.
* Clinical and outcome information available.
* Histological slides/formalin-fixed paraffin-embedded tissue tumor blocks from archive available to perform the histology analysis/frozen tissue representative of the tumor available.

Exclusion Criteria:

* Diagnosis different from undifferentiated round cell sarcomas
* Patient with no clinical or outcome information available
To Evaluate the Safety and Efficacy of Acetaminophen 650 mg and 1000mg in Dental Pain After Surgery

The objective of this study is to evaluate the safety and efficacy of acetaminophen 650 mg and acetaminophen 1000 mg in dental surgery.

This trial is to assess the relative efficacy of acetaminophen 1000 mg versus acetaminophen 650 mg over a six-hour period, in subjects experiencing at least moderate post-operative dental pain.

Eligibility Criteria:
Inclusion Criteria:

* Must be at least 16 and less than 51 years of age
* Must weigh at least 100 lbs with a body mass index of at least 18 and less than 30
* Must have up to four of their back teeth (third-molars) pulled

Exclusion Criteria:

* Cannot be allergic to acetaminophen (Tylenol)
* Cannot be pregnant (or planning to be pregnant) or nursing a baby
* Cannot have any other medical conditions that the investigator determines might compromise your safety or the study results
Reducing Hospital Falls by Empowering Nurses to Provide Ambulatory Aids

This project proposes to evaluate the potential for nurses to assess if a patient who uses an ambulatory aid at home is fit to use one in the hospital, and the effect that providing ambulatory aids to hospitalized patients will have on reducing hospital falls, with a matched pair cluster-randomized controlled trial.

Hypothesis 1: Of the patients who use an ambulatory aid at home, patients who receive an ambulatory aid in the hospital will have a lower fall rate as compared to patients who do not receive an ambulatory aid in the hospital.

Hypothesis 2: After adequate training, nurses will be able to accurately assess whether or not patients need an ambulatory aid when compared to the gold-standard assessments of physical therapists.

This research project proposes to study the effectiveness of a specific falls prevention intervention in a high risk population by providing ambulatory aids upon admission to the hospital to patients who previously used one at home after a standardized evaluation by a Registered Nurse. This will be a randomized controlled trial within three hospitals in a large academic medical center.

Primary Objectives:

Specific Aim 1: Evaluate the effectiveness in preventing falls by providing an ambulatory aid to patients who use an ambulatory aid at home, and who are deemed fit to use the device in the hospital by their nurse.

Specific Aim 2: Evaluate the nurses' ability to assess the appropriateness of providing an ambulatory aid, such as a cane or walker, to a patient who uses an assistive device at home.

Eligibility Criteria:
Inclusion Criteria:

* any one determined to be in need of walking aid and
* Can stand up from a seated position independently without assistance
* Can use ambulatory aid at home without assistance/supervision
* Can sit up in bed AND rise to a standing position independently

Exclusion Criteria:

* Not able to give consent
* Not able to use ambulatory aid independently
Show Improved Vision With the HOYA AF-1 Aspheric Intraocular Lens After Cataract Surgery

The doctors participating in this study are looking to show improved vision with the HOYA AF-1 aspheric intraocular lens after cataract surgery. They will also study the use of Revital Vision (neuro-sensory testing) in providing the highest potential for improved vision.


Eligibility Criteria:
Inclusion Criteria:

1. Patients must desire to pursue some type of mono-vision fit, mono-vision lasik, or mono-vision cataract surgery with lens implant.
2. Patients must be candidates for intraocular lens implantation for the correction of aphakia following extracapsular cataract extraction by phaco-emulsification.
3. Patients must be candidates for bilateral implantation and desiring post-operative spectacle independence through targeted mono-vision.
4. Patients must have less than 1.50 diopters of corneal astigmatism
5. Patients must have the potential for best corrected visual acuity of 20/30 or better in each eye.
6. Patients must have the mental capacity to cooperate when undergoing a detailed postoperative refractive examination.
7. Patients must be an adult.
8. Patients must provide written informed consent for cataract surgery.
9. Patients must be willing and able to return for scheduled follow-up examinations for a period of 3 months (post-second eye) post-operatively.
10. Patients must be willing and able to provide feedback to various survey questions regarding overall satisfaction and ease of adaptation to mono-vision and range of vision, etc.

Exclusion Criteria:

1. Patients with 1.50 diopters or more of corneal astigmatism
2. Patients requiring a lens power less than 6 D or greater than 30 D
3. Patients with any anterior segment pathology (chronic uveitis, iritis, iridocyclitis, rubeosis iridis, corneal dystrophy or corneal degeneration, tear film deficiency, poor pupil dilation, etc.).
4. Patients with uncontrolled glaucoma or who require current treatment for glaucoma, or with visual field loss as a result of glaucoma.
5. Patients with retinal pathology or a history of retinal detachment.
6. Patients with proliferative diabetic retinopathy, macular degeneration, or other degenerative visual disorders.
7. Patients with a history of previous ocular surgery including corneal refractive surgery.
8. Patients with congenital bilateral cataracts.
9. Patients with marked microphthalmos or aniridia.
10. Patients who have only one functioning eye.
11. Patients who do not have the potential for visual acuity of 20/30 or better in each eye.
12. Patients lacking intact binocular vision.
13. Patients who do not have an intact capsulorhexis and posterior capsular bag at the time of cataract removal and lens implantation.
14. Patients who have incomplete or damaged zonules, or who have zonular rupture during cataract removal.
15. Patients with pupils greater than 7mm
Parental Notions and Clinical Experiences About Child's Gut Comfort, Overall Satisfaction and Sense of Well-being When Consuming a New Toddler Milk

This is a prospective, open-label, single-arm study in a real-world setting of healthy Chinese toddlers provided with new toddler milk for a total of 4 weeks (28 days).

The new toddler milk contains prebiotic and an optimized fat blend of bovine milk fat, vegetable fats, and a LC-PUFA oil mixture (providing DHA and ARA). The prebiotic and bovine milk fat-based blend have shown to be able to improve digestive comfort and milk taste. Physiological factors such as physical discomfort has been shown to be associated with negative emotionality and temperament (Putnam 2012). Therefore, the investigators hypothesize that by improving digestive comfort, they are able to influence child temperament, happiness, and other behavioral characteristics.

Eligibility Criteria:
Inclusion Criteria:

1. Generally healthy toddlers born at term (37-42 weeks of gestation).
2. At enrolment visit, toddler age 12-33 months.
3. Birth weight ≥ 2500g and ≤ 4500g.
4. No known milk intolerance / allergies to cow's milk protein.
5. Habitually consuming some cow's milk or other traditional milks.

Exclusion Criteria:

1. Toddler is currently breastfed or is consuming breast milk.
2. Toddler who is experiencing growth faltering (defined as weight for length z score ≤-1.67).
3. History of preterm birth
4. Currently experiencing severe constipation.
5. Currently diagnosed with other Functional Gastrointestinal Disorders.
6. Toddlers who have known cognitive and developmental disorders.
7. Toddlers who are currently participating in or have participated in another clinical trial within 4 weeks prior to trial start.
Sensory Support Care for Elderly Patients Suffering From Alzheimer'S-type Neurodegenerative Disease

The main objective of this study is to evaluate the effect of 3 months of "Snoezelen-type" multi-sensory care sessions on NeuroPsychiatric Inventory Questionnaire (NPI-Q) scores for patients with Alzheimer's-type neurodegenerative disease.

The secondary objectives of this study are to study the following elements in relationship to the implementation of a "Snoezelen-type" multi-sensory care strategy for patients with Alzheimer's-type neurodegenerative disease:

A. to evaluate the effects on NPI-Q scores at 1 month, 6 months and 12 months .

B. evaluate the effects on quality of life (questionnaire QOL-AD) at 0 and 12 months.

C. assess changes in the "aggressive behavior" subsection of the Cohen-Mansfield Agitation Inventory (CMAI) questionnaire over 0, 1, 3, 6 and 12 months.

D. assess changes in drug consumption (anxiolytics, antidepressants, hypnotics, neuroleptics)over the study period

Eligibility Criteria:
Inclusion Criteria:

* The patient's legal representative must have given his/her informed and signed consent (or the patient if he/she is judged competent)
* The patient must be insured or beneficiary of a health insurance plan
* Alzheimer's-type neurodegenerative pathology
* The patient has been living in the participating center for \> 2 months

Exclusion Criteria:

* The patient's legal representative refuses to sign the consent (or the patient if he/she is judged competent)
* It is impossible to correctly inform the patient's legal representative
* The patient has already has Snoezelen-therapy
The Role of Referred Pain From the Retro Trochanteric Region in Patients With Knee Pain

The role of referred pain from the retro trochanteric region, in patients with knee pain. Defining and quantifying this sub group of knee patients in the investigators list of refered knee patients. Evaluating the effect of treatment. A randomized trial.

Knee pain is a great problem in the society. Besides obvious and known causes, for which there are increasing understanding and ways to treat, there is still a rather large group of patients in which the symptoms are not easily understood and harder to treat.

This group is often characterized by having symptoms ranging from months to years, having seen several physicians, gone through several x-rays/mri´s, and various treatment with no help.

The investigators find ever more suspicion towards specific mechanisms in the hip region as a source of knee pain. It is well known in pediatric medicine that children with serious disease in the hip often debut with knee pain. This relationship is not so well established in adults.

Pain in the lower extremity can arise from inflammation or strain of the retro trochanteric muscles, and/or more indirectly if these processes impact the sciatic nerve. The later explanation is commonly known as the piriformis syndrome.

Professor Oddmund Johansen has studied this type of pain extensively. In the later years he has found interest in patients with knee pain.

These patients will often have pain with deep palpation to the posterior hip region, when tightening the hip rotators with flexion and adduction, and they will often respond with pain relief, within minutes, when local anesthesia is placed on the distal attachment of the hip rotators on the posterior margin of the greater trochanter. Afterwards, lasting pain relief can be seen with a specified stretching regiment for these muscles.

The investigators will recruit suiting patients from a knee referral list. Inclusion will be based on clinical examination and whether they respond to the injection. After inclusion they will be scored with pain and quality of life forms, randomised in two groups, one with a stretching regime and one with conservative and symptomatic treatment.

There is interest in defining and quantifying this sub group of knee patients. They will be followed up after 3 months, with a new examination and scoring to evaluate the effect of the intervention.

The study will examine how the patients react and comply with the proposed diagnosis and treatment. A cost analysis will also be considered.

Eligibility Criteria:
Inclusion Criteria:

* Knee pain
* Failure to understand the pain with more conventional diagnosis
* Symptoms and retrotrochanteric pain with examination
* Pain relief with retro trochanteric local anaesthetic injection

Exclusion Criteria:

* Mental illness
* Failure to cooperate
* Not adequate Norwegian language skills
* Other well known disease explaining symptoms