Exercise Improves Gastrointestinal Function in Peritoneal Dialysis Patients

This study will investigate the impact of exercise on gastrointestinal function in peritoneal dialysis patients.

Maintaining gastrointestinal health is paramount for individuals on peritoneal dialysis, yet it frequently goes unnoticed within the broader scope of their health management. The effectiveness of dialysis treatments, along with aspects such as nutrient uptake and life quality, can be adversely affected by gastrointestinal disturbances. The volume of fluid within the peritoneal space, medications associated with dialysis, and the procedure of dialysis itself are all known to play roles in modulating gastrointestinal health.

The role of physical activity in enhancing gastrointestinal wellness among those with chronic conditions has gained acknowledgment over time. Customized exercise regimes have been shown to markedly better gastrointestinal symptoms, the efficiency of nutrient absorption, and overall life satisfaction among these patients. Notably, the specific influence of exercise on the gastrointestinal functions of individuals undergoing peritoneal dialysis has yet to be explored.

This investigation aims to assess the effects of exercise on the gastrointestinal health of peritoneal dialysis patients. Participants will be divided equally into an exercise group and a control group, following a randomized selection process. After collecting data throughout a four-month period, an analysis will be conducted to ascertain the benefits of physical activity for enhancing the gastrointestinal function of those on peritoneal dialysis. The outcomes of this study are anticipated to guide clinicians in recommending strategies to improve gastrointestinal health in this patient population.

Eligibility Criteria:
Inclusion Criteria:

1. Patients must have undergone peritoneal dialysis for more than 3 months.
2. Age between 18 and 65 years.
3. Possession of a smartphone and proficiency in its usage.
4. Willingness to provide voluntary informed consent by signing the consent form.

Exclusion Criteria:

1. Recent systolic blood pressure ≥180 mmHg or diastolic blood pressure ≥110 mmHg, or systolic blood pressure ≤90 mmHg or diastolic blood pressure ≤60 mmHg within the past week.
2. Presence of severe cardiovascular diseases, including but not limited to:

   * Heart failure classified as New York Heart Association (NYHA) functional grade IV-V.
   * Severe arrhythmias such as third-degree atrioventricular block, sick sinus syndrome, paroxysmal supraventricular tachycardia, or ventricular tachycardia.
   * Unstable angina.
   * Pulmonary arterial hypertension with pulmonary arterial pressure ≥25 mmHg.
   * Severe pericardial effusion, valve stenosis, hypertrophic cardiomyopathy, or aortic dissection.
3. Severe pulmonary diseases, including but not limited to:

   * Severe chronic obstructive pulmonary disease (COPD).
   * Pulmonary embolism.
   * Lung cancer.
   * Severe pulmonary infection.
4. Presence of deep venous thrombosis.
5. Severe neurological, muscular, bone, or joint diseases that hinder compliance with exercise.
6. Participation in other concurrent exercise programs.