Evaluation of Lung Ultrasonography Findings in Newborns With Respiratory Syncytial Virus Bronchiolitis

Respiratory Syncytial Virus (RSV) is a seasonal, highly contagious pathogen belonging to the Pneumoviridae (genus orthopneumovirus), a family of negative-strand RNA viruses. Lung ultrasonography; Today, it has become frequently used in neonatal intensive care units because it is a diagnostic, useful, harmless, radiation-free, bedside, reproducible and practical method. The primary purpose of the study is to record lung ultrasound findings and score and thus to compare the agreement between lung ultrasonography and clinical score in the diagnosis and follow-up of newborn babies who are followed up in the neonatal intensive care unit due to bronchiolitis caused by RSV and other viral factors, which are frequently encountered.

Respiratory Syncytial Virus (RSV) is a type of negative-strand RNA viruses. It is a seasonal, highly contagious pathogen belonging to the family Pneumoviridae (genus orthopneumovirus). RSV is a common cause of respiratory disease throughout life but is associated with significant morbidity and mortality, especially in infants and older adults.

RSV infections account for approximately 60% to 80% of bronchiolitis in infancy and 40% of pediatric pneumonias.

Bronchiolitis is an acute lower respiratory tract infection that affects children under one or two years of age and is the most common cause of hospitalization, according to American Academy of Pediatrics (AAP) guidelines. Diagnostic criteria for bronchiolitis are based on clinical history and examination.

Lung ultrasonography (LUS) was first used in adults in 1995, and in the last decade, lung ultrasound has proven to be a useful diagnostic tool in many pediatric and neonatal diseases, and its application and benefit in the treatment of bronchiolitis has been reported. Since AUS allows bedside assessment of the subpleural lung for density, thus reducing the quantitative ratio of airspace and space, it is reasonable to expect that a combination of clinical and ultrasound parameters may be useful. Studies have shown that qualitative and quantitative lung ultrasound findings suggest a relationship with the severity of bronchiolitis and are useful in the follow-up of patients.

Caiulo et al. They showed that AUS is a valuable tool in the diagnosis of bronchiolitis.

However, data on lung ultrasound in newborns with viral lower respiratory tract infections are quite limited.

Lung ultrasonography; Today, it has become frequently used in neonatal intensive care units because it is a diagnostic, useful, harmless, radiation-free, bedside, reproducible and practical method. In our clinic, lung ultrasonography is performed on babies hospitalized with respiratory distress. Images will be obtained using the linear probe of the device to be used for AUS. Brat et al. AUS scoring specified in the studies of Raimondi et al. and Raimondi et al. will be used.

Accordingly, both lungs will be evaluated as three areas on the right and left (anterior upper, anterior lower and lateral) and will be scored separately. Parasternal with anterior axillary line in front The area between the line is divided into two by the line passing from the nipple. The upper part is considered as the upper anterior region and the lower part is considered as the lower anterior region. The area in the middle of the anterior and posterior axillary lines is called the lateral region.

is evaluated. Each field is given a score of 0 to 3. If there were A lines, 0 points were given. If there were more than 3 B lines in an area, 1 point was given. If the B lines were very dense and there was no A line, it was evaluated as white lung and 2 points were given. If there was a consolidation image in AUS, 3 points were given. The total score was evaluated as a maximum of 18. In this study, newborn babies who were admitted and admitted to the Neonatal Intensive Care Unit of Kırıkkale University Faculty of Medicine Hospital with symptoms of viral lower respiratory tract diseases between 18/12/2023 and 01/06/2023 were clinically diagnosed with 40% of their O2 need at the 24th hour of hospitalization. Lung ultrasonography was planned to be performed in cases where the patient was overweight and/or required pressure or was intubated, and at the time of discharge. Demographic characteristics, symptoms, all routine laboratory and radiological imaging of newborn babies, and additional pathogen or pathogens will be obtained from the file information. The parameters to be recorded are shown in the Case Report Form. The primary purpose of the study is to record lung ultrasound findings and score and thus to compare the agreement between lung ultrasonography and clinical score in the diagnosis and follow-up of newborn babies who are followed up in the neonatal intensive care unit due to bronchiolitis caused by RSV and other viral factors, which are frequently encountered.

Eligibility Criteria:
Inclusion Criteria:

* All newborns hospitalized with viral lower respiratory tract findings in the neonatal intensive care unit of Kırıkkale University Faculty of Medicine Hospital
* Patients with study approval
* Patients who underwent lung ultrasonography were included in the study.

Exclusion Criteria:

* Newborns who do not lie down due to viral lower respiratory tract infection
* Patients without study consent
* Patients for whom lung ultrasonography could not be performed