original antigenic sin (English, noun)
expansion: original antigenic sin (uncountable)
Senses:
topics: immunology
medicine
sciences
glosses: The propensity of the immune system to preferentially use immunological memory based on a previous infection when a second, slightly different version of the foreign pathogen is encountered, leaving the immune system "trapped" by the first response it has made to each antigen, and unable to mount potentially more effective responses during subsequent infections.
tags: uncountable
Forms: