self
Language: English
Part of speech: adj
Pronunciation: ipa: /sɛlf/
note: Southern US, African-American Vernacular, dated
ipa: /sɛf/
ipa: /sɛl/
rhymes: -ɛlf
Forms: form: selfe
form: silf
form: silfe
Etymology: From Middle English self, silf, sulf, from Old English self, seolf, sylf, from Proto-Germanic *selbaz. Cognates include Gothic 𐍃𐌹𐌻𐌱𐌰 (silba), German selbst and Dutch zelf.
Senses: examples: text: a self bow: one made from a single piece of wood
text: a self flower or plant: one which is wholly of one colour
glosses: Having its own or a single nature or character throughout, as in colour, composition, etc., without addition or change; of the same kind; unmixed.
examples: text: I owe you much, and, like a wilful youth / That which I owe is lost; but if you please / To shoot another arrow that self way / Which you did shoot the first, I do not doubt, / As I will watch the aim, or to find both, / Or bring your latter hazard back again, / And thankfully rest debtor for the first.
ref: c. 1596–1598 (date written), William Shakespeare, “The Merchant of Venice”, in Mr. William Shakespeares Comedies, Histories, & Tragedies […] (First Folio), London: […] Isaac Iaggard, and Ed[ward] Blount, published 1623, →OCLC, [Act I, scene i]:
text: I am made of that self mettle as my sister.
ref: c. 1603–1606, William Shakespeare, “The Tragedie of King Lear”, in Mr. William Shakespeares Comedies, Histories, & Tragedies […] (First Folio), London: […] Isaac Iaggard, and Ed[ward] Blount, published 1623, →OCLC, [Act I, scene i]:
text: But were it granted, yet the heighth of these Mountains is far under the supposed place of Paradise; and on these self Hills the Air is so thin […]
ref: 1614, Walter Ralegh [i.e., Walter Raleigh], The Historie of the World […], London: […] William Stansby for Walter Burre, […], →OCLC, (please specify |book=1 to 5):
text: At that self moment enters Palamon / The gate of Venus […]
ref: 1700, [John] Dryden, “Palamon and Arcite: Or, The Knight’s Tale. In Three Books.”, in Fables Ancient and Modern; […], London: […] Jacob Tonson, […], →OCLC:
glosses: Same, identical.
glosses: Belonging to oneself; own.
examples: text: Similarity profiles between helper T cell epitopes (of self or microbial antigens and allergens) and human or microbial SWISSPROT collections were produced. For each antigen, both collections yielded largely overlapping profiles, demonstrating that self-nonself discrimination does not rely on qualitative features that distinguish human from microbial peptides. However, epitopes whose probability of mimicry with self or nonself prevails are, respectively, tolerated or immunodominant and coexist within the same (auto-)antigen regardless of its self/nonself nature. Epitopes (on self and nonself antigens) can cross-stimulate T cells at increasing potency as their similarity with nonself augments.
ref: 2000, G Ristori et al., “Compositional bias and mimicry toward the nonself proteome in immunodominant T cell epitopes of self and nonself antigens”, in FASEB Journal: the official journal of the Federation of American Societies for Experimental Biology, volume 14, number 3, →PMID, pages 431–438:
topics: immunology
medicine
sciences
antonyms: nonself
qualifier: molecular biology
glosses: Of or relating to any molecule, cell, or tissue of an organism's own (belonging to the self), as opposed to a foreign (nonself) molecule, cell, or tissue (for example, infective, allogenic, or xenogenic).
Derived terms: selfbow