extramedullary
Language: English
Part of speech: adj
Pronunciation: /ˌɛkstɹəməˈdʌləɹi/
/ˌɛkstɹəˈmɛdəlɛɹi/
/ˌɛkstɹəˈmɛd͡ʒulɛɹi/
Etymology: From extra- + medullary or extra- + medulla + -ary.
Senses: examples: text: Extramedullary hematopoiesis (EMH) is a rare disorder, defined as the appearance of hematopoietic elements outside the bone marrow or peripheral blood. The most common sites of EMH are liver and spleen, but it has been documented in other organs such as the mediastinum, lymph nodes, breast, and central nervous system. EMH occurs as a compensatory mechanism for bone marrow dysfunction in severe thalassemia.
ref: 2018, Abdulla MA, Yassin MA, Abdelrazek M, Mudawi D, Ibrahim F, Soliman DS, ElOmri H, Nashwan AJ, Fernihough L, De Sanctis V, Soliman AT, “A persistent cough as atypical clinical presentation of intrathoracic extramedullary hematopoiesis (EMH) in a female with thalassemia intermedia”, in Acta Biomedica, volume 89, number 2-S, →DOI, →PMID, pages 41–46:
topics: anatomy
medicine
sciences
antonyms: intramedullary
medullary
medullo-
glosses: Outside of a medulla.
Outside of the bone marrow, as with extramedullary hematopoiesis.
examples: text: As no complete study has been made of reflex response to stimulation of ipsilateral vagus in regard to extramedullary respiratory control system, the authors have tried to clarify the influence of the stimulation of the vagus on the ipsilateral posterior cricoarytenoid muscle (PCA).
ref: 1976, Fukuda H, Akitaya T, Kirchner JA, “Evoked response in the posterior cricoarytenoid to stimulation of the ipsilateral vagus”, in Keio Journal of Medicine, volume 25, number 3, →PMID, pages 111–122:
topics: anatomy
medicine
sciences
antonyms: intramedullary
medullary
medullo-
glosses: Outside of a medulla.
Outside of the medulla oblongata, as with extramedullary influences on control of ventilation.
examples: text: Similar mechanisms likely underlie the expression of relevant transporters and/or enzymes for the alternative nonperturbing osmolytes (11,12,35) in renal medullary tubular cells. Osmotic induction of AR2 and MI transport has also been described in extramedullary renal cells and in nonrenal cells rarely or never exposed to significant physiologic hyperosmolarity in vivo (31,39).
ref: 1993, Henry DN, Del Monte M, Greene DA, Killen PD, “Altered aldose reductase gene regulation in cultured human retinal pigment epithelial cells”, in Journal of Clinical Investigation, volume 92, number 2, →DOI, →PMID, →PMCID, pages 617–623:
topics: anatomy
medicine
sciences
antonyms: intramedullary
medullary
medullo-
glosses: Outside of a medulla.
Outside of the renal medulla, as with extramedullary electrolytes or renal tissue.
examples: text: This paper reports on neoplastic disease of the spine and spinal cord. Spinal tumors are often categorized as extradural, intradural–extramedullary, or intramedullary in location. This classification represents somewhat of an over-generalization for two reasons. First, a given lesion may reside in two compartments simultaneously. […] Second, in different cases, two lesions with identical pathology may occur in different compartments. […] Nevertheless, this classification scheme is useful, because it is traditional and helps to characterize spinal tumors.
ref: 1991, G Sze, M Twohig, “Neoplastic disease of the spine and spinal cord”, in Scott W. Atlas, editors, Magnetic Resonance Imaging of the Brain and Spine, →ISBN, pages 921–966:
text: MR imaging revealed isolated intradural-extramedullary involvement (n = 9), isolated intramedullary involvement (n = 3), combined intradural-extramedullary and intramedullary involvement (n = 3), and/or syringomyelia caused by infection and associated with chronic spinal arachnoiditis (n = 2).
ref: 1997, CC Leite, JR Jinkins, BE Escobar, AC Magalhães, GC Gomes, G Dib, SA Vargas, C Zee, AT Watanabe, “MR imaging of intramedullary and intradural-extramedullary spinal cysticercosis”, in American Journal of Roentgenology, volume 169, number 6, →DOI, →PMID, pages 1713–1717:
topics: anatomy
medicine
sciences
antonyms: intramedullary
medullary
medullo-
glosses: Outside of a medulla.
Outside of the spinal cord, as with intrameningeal but extramedullary tissues of the central nervous system.
Derived terms: extramedullarily