Survey on vaccination rate of second class vaccine and influencial factors in children in rural areas of nine counties in Henan province

Objective To understand the vaccination rate of the second class vaccine and the influencial factors in children in rural areas of nine counties in Henan province and evaluate replacement of the alternative vaccine for the first class vaccine,so as to provide a reference to increase vaccination rates of second class vaccine for the whole province and make a basis of strategy in first class vaccine application.Methods 1 463 children of age 2 to 7 years were selected by simple random sampling method,they are from 32 villages in 18 townships,nine counties,five cities such as Puyang,Xinxiang,Nanyang,Shangqiu,and Luoyang.The related knowledge of vaccination and main influencing factors were collected through the investigation from children's guardians,vaccination records were from certificate of children vaccination.The bank of data was based on EPiData 3.1 software,statistical analysis was carried out by using of Excel 2003 and SPSS 17.0.Results The vaccination rate for first dose of Human hepatitis A vaccine is the highest among those of alternative vaccines for first class vaccines in rural areas in 9 counties,accounted for 20.6%.The first dose for vaccination of ACYW135(1) menigococcal polysaccharide vaccine and group A and C menigococcal polysaccharide vaccine(1) are second among them,accounted for 13.8% and 12.9%,respectively,in chidren of school-age.The vaccination of first dose of Hib vaccine(Haemophilus influenza type b conjugate vaccine) is the highest,accounted for 46.4%,among those of the second class vaccines.The vaccination of 3 doses of Hib vaccine was vaccine(PPV23)were lower,which were 12.6%.Vaccinationrate of Varicella vaccine was 23.2%.The vaccination rate for Rotavirus vaccine(RV),Oral and Pneumonia 9.5% and 7.3%,respectively.The results from logistic regression analysis for single factor and multiple factors showed that inoculation way,children's status and price of vaccine were the main influencing factors related to vaccination of second class vaccins.The proportion for vaccination in the township clinics for inoculation 4 to 6 vaccines and more than 7 vaccines(22.5% and 6.9%)were higher than those in village(12.8% and 1.9%).Vaccination rate in scattered children was higher than that of children in kindergarten(P0.01).Guardian's education,family income,inoculation notification,and children staying or not staying at home(not with their parents) had a little effect or no effect on the inoculation of second class vaccines(P 0.05).Conclussion The replacement of vaccination rate and variety of second class vaccine to first class vaccine were different in different counties.It was due to different inoculation metod,vaccine price,related culture background and degree of understanding immunization that make a great difference for vaccination of second class vaccines in different areas.On the purpose to increase vaccinatuion rate for second class vaccines,it should extend the scope of vaccination in township as a unit in service for out-patients,reduce prices of these vaccines and make a good properganda.