cssi/SciSciGPT-SciSciNet huggingface dataset:
Discourses of the City: Policy and Response in Post–Transitional Barcelona

Contemporary urban planning in barcelona reflects both a historical process through which the city has been defined and a rapid political evolution since the end of the Franco regime, during which urban interests were debated intensely. This article focuses on the emergence of new discourses about the city in the transitional and the current post-transitional period of Spanish democracy. It also contrasts hegemonic models, as realized in rhetoric, planning, and construction, with other voices from the Raval, a marginal downtown neighborhood that has become a particular focus of urban renovation. The article argues that analysis of the formation of a new orthodoxy in city planning must be nuanced both by critical readings and by appreciation of alternative values in urban life. [Spain, urban planning, urban space, class conflict]
Extensional flow‐induced crystallization in polyethylene melt spinning

Polyethylene was spun into a heated chamber, with the spin-line temperature controlled in the range of 90-120°C. Within narrow limits, the stretch rate of the fiber was also controlled. Spin-line and crystallization onset conditions were characterized. Characteristics of fibers as-spun were measured via wide-angle x-ray scattering (WAXS), density, scanning electron microscopy, and differential scanning calorimetry. Spin-line data indicate that elongational flow enhances crystallization rate and that time under spin-line conditions is an important parameter. Analysis of WAXS data shows a typical "b-axis radial' orientation, the details of which change with spin-line parameters. This orientation is consistent with growth of lamellar crystals on extended-chain fibrils (shishkebab model). Other physical data are also consistent with this microstructure. Microcamera x-ray patterns show a similarity of microstructure generation in spinning and drawing.
Effects of Physical Atypicality on Children's Social Identities and Intergroup Attitudes.

This is the authors' accepted manuscript, post-peer review. The publisher's official version is available electronically from: http://dx.doi.org/10.1177/0165025407081472.
Non-random oscillation in the response-duration curve of electrographic activation

Abstract The response-duration curve for the alpha-blocking response to a bright double flash of light was studied in 25 normal subjects. Each individual was subjected to 60 stimulus presentation on six separate occasions, five of them under various drugs and one under a placebo. Data for the placebo and for methamphetamine are presented. The curve of mean duration of alpha blocking (placebo) for 60 trials indicated a roughly exponential decrement between trials 1 and 29. From trial 30 on to 37 there was a steady increase in mean values, followed by a second decrease and then a second increase in the last five trials. The curves for individuals revealed more marked oscillation but slight differences in phasing and frequency resulted in a smoothed curve for the whole population. Nevertheless, 16 of the 25 subjects had a periodicity precisely concordant with that in the mean data. Amphetamine produced a striking increase in mean response duration with stimulus repetition. However, marked oscillations were observed in over one-third of the cases; the remainder showed changes in rate of increase which, on a mean plot, also suggested the presence of an oscillatory process. The data indicate that within the time and parametric limits of this experiment there is a non-random oscillatory process affecting alpha-blockade response duration which is superimposed upon the habituation curve. Recognition of this oscillation may be important in assessing the effect of drugs or other procedures on the pattern of habituation.
Differential expression of Toll-like receptor 2 (TLR2) and responses to TLR2 ligands between human and murine vascular endothelial cells:

Toll-like receptors (TLRs) initiate and maintain host defenses and inflammation, and directly contribute to diseases such as atherosclerosis. It is not completely understood in what cell types proatherogenic TLR-induced signaling arises and, particularly, there is uncertainty regarding the potential functional role of TLR2 in endothelial cells (ECs). We determined TLR2 and TLR4 gene expression in four different human and two different murine primary ECs using gene array analysis, RT-PCR, and flow cytometry and confirmed these data by functional studies by stimulating ECs with the corresponding TLR ligands. TLR4 was expressed in all human and murine ECs and these cells responded to stimulation with LPS. Faint expression of TLR2 was observed in human ECs, whereas murine ECs express considerable amounts of TLR2 mRNA. Human ECs failed to respond to TLR2 ligands while murine ECs responded to TLR2 ligands. Furthermore, in murine ECs, TLR2 was located on the cell surface while in human ECs, TLR2 was sequestered ...
Observing the 3-dimensional distribution of bio-optical properties of West Florida Shelf waters using gliders and autonomous platforms

Bio-optical data, such as optical backscattering and the fluorescence, provides critical information about the marine environment and can be important variables to include in a coastal ocean observation system. Researchers at the College of Marine Science and Center for Ocean Technology at the University of South Florida have customized Autonomous Underwater Vehicles (AUVs) with optical sensors and deployed the vehicles in the coastal waters of the West Florida Shelf. The vertical, spatial, and temporal measurements from these platforms complement satellite remote sensing data, which are limited to synoptic observations of near-surface waters. Recently, both bio-optical (optical backscattering, red/chlorophyll fluorescence and colored dissolved organic matter fluorescence) and light field measurements (multi-spectral downwelling irradiance and upwelling radiance) were made from customized gliders. The combination of these measurements with those from other autonomous profiling platforms (e.g. Bottom Stationed Ocean Profiler, BSOP), permits estimation of the 3-dimensional distribution of bio-optical properties. Bio-optical data gathered during recent glider deployments has clarified both the utility of optical sensors and the need for additional sensor validation efforts. Initial analysis of West Florida Shelf glider data suggests that AUVs with optical sensors can not only provide insights into the 3-dimensional distribution of water properties, but also provide unique information about the location of harmful algal blooms.
Inhibition of intestinal cholesterol absorption decreases atherosclerosis but not adipose tissue inflammation

Adipose tissue inflammation is associated with insulin resistance and increased cardiovascular disease risk in obesity. We previously showed that addition of cholesterol to a diet rich in saturated fat and refined carbohydrate significantly worsens dyslipidemia, insulin resistance, adipose tissue macrophage accumulation, systemic inflammation, and atherosclerosis in LDL receptor-deficient (Ldlr−/−) mice. To test whether inhibition of intestinal cholesterol absorption would improve metabolic abnormalities and adipose tissue inflammation in obesity, we administered ezetimibe, a dietary and endogenous cholesterol absorption inhibitor, to Ldlr−/− mice fed chow or high-fat, high-sucrose (HFHS) diets without or with 0.15% cholesterol (HFHS+C). Ezetimibe blunted weight gain and markedly reduced plasma lipids in the HFHS+C group. Ezetimibe had no effect on glucose homeostasis or visceral adipose tissue macrophage gene expression in the HFHS+C fed mice, although circulating inflammatory markers serum amyloid A (SSA) and serum amyloid P (SSP) levels decreased. Nevertheless, ezetimibe treatment led to a striking (>85%) reduction in atherosclerotic lesion area with reduced lesion lipid and macrophage content in the HFHS+C group. Thus, in the presence of dietary cholesterol, ezetimibe did not improve adipose tissue inflammation in obese Ldlr−/− mice, but it led to a major reduction in atherosclerotic lesions associated with improved plasma lipids and lipoproteins.
Bilingual workplaces: integrating cultural approaches to information literacy into foreign language educational practices

This paper explores how a foreign language librarian investigated workplace information environments of bilingual (Spanish/English) professionals in the United States in order to design more relevant information literacy (IL) instruction. Drawing from interviews and participant observations of professionals whose careers correspond with Spanish language student graduate opportunities, the primary goal of the paper is to provide an initial understanding of the information environments of professionals in bilingual workplaces. The paper will then describe how this data will be used to design appropriate learning opportunities for Spanish undergraduates. Through reflecting on these multilingual information experiences, the paper also considers the role of workplace IL within higher education as well as contributing more broadly to studies on cultural approaches to IL. Accordingly, this paper will be of interest to foreign language librarians, as well as librarians who work with global studies, international relations or bilingual and international populations.
Perinatal Transmission of Ureaplasma urealyticum: Current Concepts Based on Review of the Literature

Ureaplasma urealyticum is a common inhabitant of the urogenital tract of pregnant women. This mycoplasma is transmitted from a colonized woman to her newborn infant in one of three ways: (1) in utero either transplacentally from the mother's blood or by an ascending route secondary to colonization of the mother's urogenital tract; (2) at delivery by passage through a colonized birth canal; and (3) postnatally by horizontal or nosocomial transmission. The rate of vertical transmission ranges from 18% to 55% among full-term infants and from 29% to 55% among preterm infants. The rate of vertical transmission is not affected by method of delivery but is significantly increased when chorioamnionitis is present. Moreover, colonization of the infant with U. urealyticum occurs despite delivery by cesarean section with intact fetal membranes; ureaplasmal infection of the amniotic sac without rupture of membranes has been well described. Ultimately, the prevalence of infant colonization will depend on the prevalence of maternal colonization in a given population. However, the rate of colonization appears to be higher in very-low-birth-weight (VLBW) infants. Given this finding, as well as the potential for serious disease that could be attributed to U. urealyticum in this population, it seems reasonable to target the VLBW infant for a clinical treatment trial to determine if eradication of this organism will decrease the incidence of chronic lung disease.
Phase-matched harmonic generation in lithium triborate (LBO)

The authors present refractive index, thermo-optic, phase-matching angle, nonlinear coefficient, absorption, and scattering data on lithium triborate (LBO) crystals. They briefly discuss the material quality of the crystals, including the results of calorimetric absorption measurements in the infrared and ultraviolet. They present a new set of refractive index values with better than fourth decimal place precision, as well as measurements of the thermo-optic parameters. The nonlinear coefficients and other frequency conversion parameters of LBO were investigated by studying the phase-matched generation of Nd:YAG harmonics. These results are summarized. The authors discuss angular and thermal bandwidths for phase matching. Finally, they compare the efficiency of LBO with that of several other frequency conversion crystals for a common commercial application-the generation of Nd:YAG harmonics. >
Spectroscopic Studies of "Exciplex Tuning" for Dicyanoaurate(I) Ions Doped in Potassium Chloride Crystals

Photoluminescence and Raman results for single crystals of KCl doped with KAu(CN)2 with different Au content are presented and compared with results for pure KAu(CN)2 crystals. Photoluminescence spectra of the doped crystals show three major UV−vis bands that can be resolved by varying the excitation wavelength. Spectroscopic and computational evidence suggests the formation of Au−Au bonded excimers and exciplexes in this doped system. The excimer/exciplex luminescence bands can be tuned in a given crystal by site-selective excitation and their relative intensities tuned by varying the dopant concentration. Microsecond lifetimes were observed for the various luminescence bands, suggesting Au-centered phosphorescent emissions. Raman spectral analysis was used successfully to correlate with the luminescence bands observed in pure and doped crystals of [Au(CN)2-] and [Ag(CN)2-] systems. The Raman νCN bands corresponding to various sites of [Au(CN)2-]n and [Ag(CN)2-]n clusters in various crystals correlated w...
Home Science and the Nationalization of Domesticity in Colonial India

This paper investigates the late colonial origins of Home Science in British India. It deals most intensively with the institutionalization of Home Science in Madras Presidency and attends to the roles played by both the colonial state and Indian women's organizations in its establishment. Though the focus is on Madras because the efforts of those based there influenced the later course of Home Science education, the activities of Madras educators, policy makers and reformers are also situated within a wider frame of transregional and imperial relations forged through reform projects, missionization, travel and education. Consideration of Home Science education in this wider context reveals the socio-political constraints an opportunities of, as well as the ideological interests at work in, its establishment. The paper finds that, at its inception, Home Science was the product of strategic alliances among colonial authorities, Indian social reformers, and Indian nationalists — all of whom, despite other differences, considered the home a site of and symbol for nationalist modernity. Home Science is shown to have relied on and helped shape a set of discourses that can be deemed ‘feminist nationalist’ in that they were engaged dialectically with anti-colonial nationalisms and with internationalist feminisms. Using Home Science as a lens, this paper provides a window on a set of late colonial debates that, informed by nationalist struggles and goals, sought to reshape the meaning and scope of both female agency and domesticity.
The role of prophylactic tamsulosin (Flomax) in patients undergoing prostate 125-I seed implants for prostate carcinoma: final report of double-blind placebo-controlled randomized study

Materials/Methods: A single institution, double blind, placebo controlled, randomized trial for patients undergoing 125I prostate implant (PI) comparing prophylactic Tamsulosin (Flomax) vs. placebo. Eligibility criteria include patients undergoing PI, who were not taking Tamsulosin (Flomax) or other alpha-blockers prior to PI. The patients received either placebo or Tamsulosin (Flomax)(0.8 mg) to be taken PO once a day). All patients started the medication 4 days prior to prostate implant for duration of 60 days after PI. The American Urologic Association (AUA) symptom index questionnaire was used at baseline and on a weekly basis for 8 weeks to assess the severity of urinary symptoms after PI. For quality assurance purpose, all AUA questionnaires were conducted by one physician (ME). Patients were taken off the study if they developed urinary retention, had intolerable urinary symptoms, or did not wish to continue with the trial. Repeated measures analysis of variance (ANOVA) was done to see if there was a difference in AUA scores between the two treatment arms over the duration of the study period. Unpaired t-tests were done to compare AUA score between the two arms on a week by week basis.
The Multiple, Distinct Ways that Personality Contributes to Alcohol Use Disorders

There is little question of whether personality is associated with problematic alcohol involvement (such as alcohol use disorders; AUDs); it clearly is. However, the question remains: how or why is personality related to risky drinking and AUDs? To address this question, theoretical models have been posited regarding the causal effects of personality on alcohol use and related problems. In this article, several of these models are summarized and reviewed. Future research directions are discussed, including possible frameworks that serve to integrate various models of the personality-AUD relation.
5. TWO VERSIONS OF A CONSTRUCTIVIST VIEW OF HISTORICAL WORK

Narrativist philosophy of history popularized a constructivist view arguing that historical works are not simple depictions of the past but rather are complicated constructions. According to narrativists, historians engage in a creative activity of proposing points of view, interpretations, or theses on the past that do not straightforwardly reflect past events. Although this is a broad constructivist view behind the theorizing of a number of authors, it is possible to distinguish within this line of thinking at least two general proposals about how to understand historical works. The first, defended for instance by Frank Ankersmit, maintains that historical works are representations of the past. Nevertheless, these representations are not descriptions of past events—they represent in a special way that could be characterized via a certain complexity, indirectness, holism, and a retrospective approach. The second proposal, presented in the work of Paul Roth and Jouni-Matti Kuukkanen, discards the epistemic framework of representation and understands historical works as the outcome of specific practices. In this article, I focus on these two constructivist versions, which could be called representationalism and non-representationalism. I analyze their crucial features, discuss their differences, and dispute the accusation that the latter view formulates an extreme theory of history. I argue that non-representationalism does not erase the notion of the past from its account of history; it merely attributes to the past a function different from the one it has within the representationalist paradigm.
Guggulsterones induce apoptosis and differentiation in acute myeloid leukemia: Identification of isomer-specific antileukemic activities of the pregnadienedione structure

In this study, the antileukemic effects of three isomeric pregnadienedione steroids [i.e., cis -guggulsterone, trans -guggulsterone, and 16-dehydroprogesterone] were investigated in HL60 and U937 cells as well as in primary leukemic blasts in culture. Our results show that all three compounds inhibited the proliferation of HL60 and U937 cells, with IC50s ranging from 3.6 to 10.9 μmol/L after treatment for 6 days. These growth inhibitory effects correlated with externalization of phosphatidylserine and loss of mitochondrial membrane potential, suggesting that these isomeric steroids induce apoptosis in leukemia cells. z-VAD-fmk prevented phosphatidylserine externalization but not mitochondrial membrane potential loss, indicating that mitochondrial dysfunction occurred in the absence of caspase activation. Interestingly, although all three compounds increased the generation of reactive oxygen species and decreased phosphorylation of extracellular signal-regulated kinase, only cis -guggulsterone induced a rapid depletion of reduced glutathione levels and oxidation of the mitochondrial phospholipid cardiolipin. 16-Dehydroprogesterone and trans -guggulsterone induced differentiation of HL60 and NB4 cells as evidenced by increased surface expression of CD11b and/or CD14, and all three steroids rapidly induced mitochondrial dysfunction and phosphatidylserine externalization of CD34-positive blasts from primary leukemic samples. This study is the first to show that guggulsterones and 16-dehydroprogesterone exert antileukemic effects via the induction of apoptosis and differentiation and, more importantly, identifies the pregnadienedione structure as a potential chemotherapeutic scaffold. [Mol Cancer Ther 2005;4(12):1982–92]
Mental Competence and End-of-Life Decision Making: Death Row Volunteering and Euthanasia

This article reports on a qualitative study of defense attorneys' perceptions of the mental competence or rationality of death row inmates' decisions to waive habeas appeals and proceed directly to execution. Interviews were conducted with twenty attorneys who have either directly represented or been closely involved with would-be volunteers. Through analytic comparison with another end-of-life decision, euthanasia, this article reports on four themes from the interviews: (a) attorneys' perceptions of the legal standard of competence, (b) their perceptions of the competency evaluation process, (c) implications of competing interpretive frames (i.e., volunteering vs. suicide), and (d) the rationality of decisions to waive appeals. Implications of research findings, particularly in terms of recent restructured models of competence, are also discussed.
Notch Activation Is Dispensable for D, L-Sulforaphane-Mediated Inhibition of Human Prostate Cancer Cell Migration

D, L-Sulforaphane (SFN), a synthetic racemic analog of broccoli constituent L-sulforaphane, is a highly promising cancer chemopreventive agent with in vivo efficacy against chemically-induced as well as oncogene-driven cancer in preclinical rodent models. Cancer chemopreventive effect of SFN is characterized by G2/M phase cell cycle arrest, apoptosis induction, and inhibition of cell migration and invasion. Moreover, SFN inhibits multiple oncogenic signaling pathways often hyperactive in human cancers, including nuclear factor-κB, Akt, signal transducer and activator of transcription 3, and androgen receptor. The present study was designed to determine the role of Notch signaling, which is constitutively active in many human cancers, in anticancer effects of SFN using prostate cancer cells as a model. Exposure of human prostate cancer cells (PC-3, LNCaP, and/or LNCaP-C4-2B) to SFN as well as its naturally-occurring thio-, sulfinyl-, and sulfonyl-analogs resulted in cleavage (activation) of Notch1, Notch2, and Notch4, which was accompanied by a decrease in levels of full-length Notch forms especially at the 16- and 24-hour time points. The SFN-mediated cleavage of Notch isoforms was associated with its transcriptional activation as evidenced by RBP-Jk-, HES-1A/B- and HEY-1 luciferase reporter assays. Migration of PC-3 and LNCaP cells was decreased significantly by RNA interference of Notch1 and Notch2, but not Notch4. Furthermore, SFN-mediated inhibition of PC-3 and LNCaP cell migration was only marginally affected by knockdown of Notch1 and Notch2. Strikingly, SFN administration to Transgenic Adenocarcinoma of Mouse Prostate transgenic mice failed to increase levels of cleaved Notch1, cleaved Notch2, and HES-1 proteins in vivo in prostatic intraepithelial neoplasia, well-differentiated carcinoma or poorly-differentiated prostate cancer lesions. These results indicate that Notch activation is largely dispensable for SFN-mediated inhibition of cell migration, which should be viewed as a therapeutic advantage as Notch activation is frequent in human prostate cancers.
Research Note: Comparison of Microscopic and Laser Diffraction Methods for Measuring Sarcomere Lengths of Contracted Muscle Fibers of Chicken Pectoralis Major Muscle

Abstract The objective of the present study was to compare the effectiveness of a microscopy method with a laser diffraction method for measuring sarcomere lengths of chicken pectoralis major (p. major) muscle fibers exhibiting various contraction states. Chicken p. major muscles were excised from the animals at death. Samples of each muscle were treated with pH-buffered (5.0 and 7.5) isoionic CaCl2, KCI, or ethylene glycol bis-(b-aminoethyl ether) N,N,N′,N′-tetraacetic acid (EGTA) solutions in order to produce variability in the degree of fiber contraction. Sarcomere lengths (SL) of the fibers were observed using light microscopy and a laser diffraction method. The methods gave comparable results for sarcomere lengths greater than 1.6 μm. However, for SL less than 1.6 μm, sarcomere contraction was not accurately assessed by the laser diffraction method.
Microbial Indicators of Nutrient Enrichment: A Mesocosm Study

Microbial communities are in close contact with the wetland soil microenvironment and can therefore function effectively as monitors of soilpollution.Theobjectiveofthisstudywastodeterminechangesinthe functional responses of microbial communities as a result of an external input of nutrients, while controlling for vegetation. A controlled experiment was performed at the mesocosm scale, consisting of two 1 m by 13 m raceways containing an organic peat soil, each planted with Cladium sp. and Typha sp. communities. One of the mesocosms was loaded with N (2 g N m 22 yr 21 )a nd P( 1 gPm 22 yr 21 ) for 18 mo. Nutrient loading resulted in increases in the soil and detritus labile nutrient pools, however, insufficient N and P where added to significantly alter their total levels. Over the experimental period, the extracellular enzyme acid phosphatase showed a significant decrease in activity across both plant communities (P , 0.01) in contrast to bglucosidase activity, which varied primarily by plant community. Other microbial response variables such as the microbial activities (CO2 and CH4production,P50.0016and0.0213,respectively),microbialbiomass (P 5 0.0018) also varied primarily by vegetation type, with Typha sp. dominated areas exhibiting the highest level of activities. The nutrient dosing experiment indicated that the most immediate microbial response measures to nutrient enrichment are those directly associated to specific nutrients, such as P or N, while other measures showed a more complex response involving C source (e.g., vegetation type).
Effect of magnesium mica on performance and carcass quality of growing-finishing swine.

A total of 240 crossbred pigs were used in two experiments to determine the effect of feeding magnesium mica (MM) during the growing-finishing period on animal performance and pork carcass characteristics. All pigs were blocked by weight, and treatments were assigned randomly to pens (five pigs/pen) within blocks. In each experiment, eight pens were allotted randomly to one of three treatments: 1) a negative control corn-soybean meal starter, grower, and finisher diet devoid of supplemental magnesium; 2) the control diets supplemented with 1.25% MM; and 3) the control diets supplemented with 2.50% MM. In Exp. 1, pigs were slaughtered at the University of Arkansas Red Meat Abattoir, whereas pigs in Exp. 2 were transported to a commercial pork packing plant and slaughtered according to industry-accepted procedures. In both experiments, dietary supplementation of MM had no (P > .10) effect on ADG, ADFI, or gain:feed ratio at any phase during the growing-finishing period. In Exp. 1, MM supplementation had no (P > .10) effect on carcass fatness or muscling. Moreover, Japanese color scores were not (P > .10) affected by feeding pigs MM; however, American color scores increased linearly (P .10) affect L* and b* values for the longissimus muscle (LM), there was a linear increase (P .10) by inclusion of MM in the diet. Results from this study confirm that inclusion of MM, an inexpensive, inorganic magnesium source, in diets of growing-finishing swine has beneficial effects on pork carcass cutability and quality with no deleterious effects on live animal performance.
Mechanism of Bias Filament Rupture in Fatigue of Nylon

Abstract Cords in nylon tires fail at points of stress concentration owing to rupture of individual filaments by a characteristic fracture which occurs at an angle to the filament axis. Filaments fail by a crack growth process initiated at the fiber surface at defect sites. Crack formation and growth in single filaments were observed to occur at both natural and artificially induced surface defects. Failure begins at the compression side of the bend in filaments subjected to repeated cyclic bending. Similar findings were indicated for ductile metals. Fatigue failures in nylon filaments were related to the cyclic bending associated with compressive loading on inner ply cords of tires.
Research Review: Environmental exposures, neurodevelopment, and child mental health – new paradigms for the study of brain and behavioral effects

Background Environmental exposures play a critical role in the genesis of some child mental health problems. Methods We open with a discussion of children's vulnerability to neurotoxic substances, changes in the distribution of toxic exposures, and cooccurrence of social and physical exposures. We address trends in prevalence of mental health disorders, and approaches to the definition of disorders that are sensitive to the subtle effects of toxic exposures. We suggest broadening outcomes to include dimensional measures of autism spectrum disorders, attention-deficit hyperactivity disorder, and child learning capacity, as well as direct assessment of brain function. Findings We consider the impact of two important exposures on children's mental health: lead and pesticides. We argue that longitudinal research designs may capture the cascading effects of exposures across biological systems and the full-range of neuropsychological endpoints. Neuroimaging is a valuable tool for observing brain maturation under varying environmental conditions. A dimensional approach to measurement may be sensitive to subtle subclinical toxic effects, permitting the development of exposure-related profiles and testing of complex functional relationships between brain and behavior. Questions about the neurotoxic effects of chemicals become more pressing when viewed through the lens of environmental justice. Conclusions Reduction in the burden of child mental health disorders will require longitudinal study of neurotoxic exposures, incorporating dimensional approaches to outcome assessment, and measures of brain function. Research that seeks to identify links between toxic exposures and mental health outcomes has enormous public health and societal value.
An Analysis of the Efficiency Selected Aspects of Machine of and Effectiveness Instruction

(1962). An Analysis of the Efficiency Selected Aspects of Machine of and Effectiveness Instruction. The Journal of Educational Research: Vol. 55, No. 9, pp. 467-471.
Pregnancy and Fertility in Systemic Lupus Erythematosus

Attention to reproductive issues is an important aspect of caring for systemic lupus erythematosus (SLE) patients. While primary infertility is not increased among these patients, secondary infertility may be increased, most commonly related to active disease, renal insufficiency, prior medication exposure, and advanced maternal age. Assisted reproductive technologies can be used in SLE with the same restrictions that apply to pregnancy. During pregnancy, disease is more likely to flare, in particular in those with renal disease and active disease in the 6 months preceding pregnancy. Preeclampsia and maternal morbidity are more common in SLE patients, and poor pregnancy outcomes are increased, with higher rates of miscarriage, preterm premature rupture of the membranes, small for gestational age infants, and fetal death. While not all medications can be used during pregnancy, hydroxychloroquine, glucocorticoids, and the immunosuppressives azathioprine, cyclosporine, and tacrolimus can be prescribed. Carefully timing pregnancy at a time of disease quiescence on safe medications and using a multidisciplinary care team including rheumatology and maternal fetal medicine can lead to good pregnancy outcomes in most SLE patients.
Reactions to resolved states and to non-fusion channels for /sup 16/O+/sup 48/Ca at E/sub lab/ = 158. 2 MeV

In a study of the system /sup 16/O+/sup 48/Ca at E/sub lab/(/sup 16/O) = 158.2 MeV, we have measured elastic, inelastic, and single-nucleon transfer cross sections to resolved final states, and the non-fusion reaction cross section. The measured cross sections to resolved states generally agree with the predicted magnitudes and angular distributions from exact finite-range distorted-wave Born approximation calculations. The total non-fusion reaction cross section, sigma/sub NF/, is measured to be 0.66/sub -0.07//sup +0.27/ b. These results are compared with other studies made at different bombarding energies, and for other systems.
Control of the Corn Earworm on Sweet Corn in Eastern Nebraska

Results of field experiments conducted at Lincoln, Nebraska, in August, the month in which sweet corn is usually harvested in eastern Nebraska, demonstrated that carbaryl was more effective than DDT in controlling Heliothis zea Boddie on sweet corn. Zectran® (4-dimethylamino-3,5-xylyl methylcarbamate) was as efficient as carbaryl but Matacil® (4-(dimethylamino)-m-tolyl methylcarbamate), Bayer 37344 (4-(methylthio)-3,5-xylyl methylcarbamate), Isolan® (l-isopropyl-3-methyl-5-pyra-zolyl dimethylcarbamate), dimetilan, UC-8305 (3-chloro-5-methyl-3-thio-2,4-dioxa-3-phosphabicyclo [4.4.0]decane), and dioxathion were not. Bacillus thuringiensis Berliner was completely ineffective against earworms. The most feasible control schedule for eastern Nebraska was found to be 4 applications 3 days apart, beginning 2 days after the very first silks are observed.
Recent advances in designing balun-free interstitial antennas for minimally-invasive microwave ablation

We discuss recent advances in the design of balun-free interstitial antennas for minimally-invasive microwave ablation (MWA). Specifically, two different classes of balun-free MWA antennas are discussed in this paper. The first class of antennas consists of monopole-type radiators fed at their bases using coaxial cables and operated at the second resonant frequency. Under these conditions, a compact specific absorption rate (SAR) pattern is achieved without the need to use a coaxial balun encompassing the outer periphery of the feeding coaxial cable as is done in conventional coax-fed MWA antennas. The second class of antennas consists of balanced dipole or loop antennas fed with inherently balanced, shielded transmission lines. In such a structure, the current flowing on one conductor of the feeding line (and the antenna arm) is balanced by the current flowing on the other conductor (the other antenna arm). Therefore, no RF current flows on the outer surface of the floating shield and the antenna achieves a compact SAR pattern and localized heating zone. Design considerations, principles of operation, and measurement results including the results of ex vivo ablation experiments for representative prototypes of both classes of antennas are presented and discussed in the paper.
Review and prospect of TB control in China

This paper summarize the status and achievements of tuberculosis( TB) control in China by describing TB's prevalence in China and in the world,reviewing its control during the past years and prospecting the future challenge and the action of controlling. China is one of the 22 TB high-burden countries in the world,and the drug-resistant TB epidemic situation is serious,the prevention and control task has a long way to go. Over the years,with the great attention from the government,TB prevention and control work in China follows a series of international and domestic strategy and policy,has achieved remarkable success,has established a relatively mature control system,and effectively control the TB epidemic. At the same time,our control mode are highly praised by WHO. In the face of complex and changeful TB epidemic situation,the future of our TB control still needs the government's strong commitment and support to fully implement technology strategy to control the source of infection,to control the incidence and development of TB effectively
The management of intermittent exotropia: a comparison of the results of surgical and nonsurgical treatment.

(1977). The Management of Intermittent Exotropia: A Comparison of the Results of Surgical and Nonsurgical Treatment. American Orthoptic Journal: Vol. 27, No. 1, pp. 61-67.
The consumption of canned food and beverages and urinary Bisphenol A concentrations in NHANES 2003-2008.

Abstract Background Exposure to Bisphenol A (BPA) is ubiquitous and includes dietary and environmental pathways. BPA is rapidly glucuronidated in the body, and both BPA and its conjugates can be readily measured in urine. Objectives To investigate the contribution of canned food and beverages, known sources of BPA contamination, to BPA biomarkers of exposure using dietary and urinary BPA concentration information in a representative sample of the U.S. population. Methods We evaluated 7669 NHANES 2003–2008 participants 6 years and older with 24-h dietary recall information and urinary BPA concentrations available. Using linear regression models, we evaluated the associations between recent canned food and beverage consumption and urinary BPA concentrations, adjusting for potential confounders. Results We found 9% of our participants consumed one canned food in the past 24 h and 2% consumed two or more canned foods. The consumption of one canned food vs. none was associated with 24% (95% CI 1.11, 1.38) higher urinary BPA concentrations. The consumption of two or more canned foods vs. none was associated with 54% (95% CI 1.27, 1.88) higher urinary BPA concentrations. The consumption of one or more of some specific types of canned foods vs. none were associated with higher urinary BPA concentrations: 41% (95% CI 1.23, 1.63) higher BPA for vegetable and fruit, 70% (95% CI 1.18, 2.44) higher for canned pasta, and 229% (95% CI 1.22, 4.30) higher for canned soup. Canned beverages were not associated with urinary BPA concentrations. Conclusions Canned food, including some specific types such as canned vegetable and fruit, canned pasta, and canned soup were associated with higher levels of urinary BPA concentrations.
The prospectus of activism: discerning and delimiting imagined possibility

AbstractThis article aims to articulate a new agenda in the scholarship of social movements. Specifically, it seeks to turn attention to the assumptions that undergird activism. Rather than studying movements themselves, we can study them as the embodiment of collective expectation in a particular public. We can learn more about the broader society in which movements are embedded by asking how activists and the public they seek to engage determine what is within the realm of possibility. I refer to the imagined horizon of possibility as the activist prospectus. To illustrate the importance of prospectus, I draw upon a case study of environmental activism in Samara, Russia. Ethnographic observation and analysis yield insights into subjective perceptions that help explain the weakness of civil society within Russia.
Molecular Detection of Circulating Tumor Cells and Cell-Free Nucleic Acids

One of the key roles performed by pathologists is determination of the presence or absence of tumor in clinical samples. This is the basis for most approaches to staging, monitoring response to treatment, and detecting relapse of neoplasia and, as such, is a critical step in determining the course of patient management. Pathologists have utilized a variety of methods, continually seeking to improve assay performance and thus patient outcome. The literature reflects this quest, including reports assessing the increased sensitivity afforded by immunohistochemistry (IHC), flow cytometry, and, more recently, molecular approaches for the detection of tumor cells and nucleic acids in blood and bone marrow samples. The goal is, of course, the more accurate detection of disease spread and, ultimately, better patient care.
Late Miocene three-toed horse Protohippus (Mammalia, Equidae) from southern Alabama

Dental and postcranial remains of a donkey-sized, three-toed, primitive horse were collected from the “Undifferentiated Miocene” Ecor Rouge Sand (which underlies the widespread Citronelle Formation) from the Mauvilla site in southern Alabama. These fossils probably pertain to a single individual of Protohippus gidleyi Hulbert, 1988. This represents an exceedingly rare occurrence of a late Tertiary land mammal from the central Gulf Coastal Plain and allows comparisons with better-known, contemporaneous land-mammal assemblages from Florida. Based on the known biochronology of Protohippus gidleyi from other localities, and the stratigraphic position of the Mauvilla record, the age of: 1) the Ecor Rouge Sand is late Miocene (latest Clarendonian to early Hemphillian landmammal “age”), between 9.0 to 6.5 Ma; and 2) the overlying Citronelle Formation near its type locality in southern Alabama is therefore late Miocene or younger.
Determining the CQC-Mediated Interactions in the Mucin 1 Homodimer

Mucin 1 (MUC1) is a highly glycosylated single pass membrane protein that serves as a selective barrier against pathogens and engages in signal transduction influencing cellular growth and differentiation. Overexpression of mucins have been linked to 80-90% of all human solid tissue cancers. Constitutive homodimerization, as a result of overexpression, leads to the formation of complexes with growth factor receptors and targeting to the nucleus, where MUC1 interacts with effector proteins regulating gene expression.Recent studies have shown that the MUC1 cytosolic membrane proximal CQC motif promotes dimerization under oxidizing conditions, suggesting that the motif may act as a redox switch in response to changes in oxidant levels. Preliminary studies have shown that the transmembrane domain (TMD) of MUC1 lacking the CQC motif form weak dimers, confirming their contribution to dimerization. Also, our results show that TMDs with the CQC motif dimerize strongly when the motif is in an oxidizing environment, further enforcing the role of the motif acts as a redox switch.Using the ToxR dimerization assay, the effects of single amino acid substitutions in TMDs with the CQC juxtamembrane area are analyzed. With these substitutions, the dimer interface can be elucidated. Our goal is to determine (1) whether certain amino acids in the TMD play a key role in forming MUC1 homodimers, and (2) whether the CQC motif induces a structural change when it functions as a redox switch. These conclusions will contribute to our understanding of MUC1 dimerization and provide insights for the development of novel therapeutic strategies.
Some Other Procedures Briefly

There are statistical learning procedures not discussed earlier that can be framed as regression analysis and deserve a least a brief conceptual overview. These include neural networks, Bayesian additive regression trees, and reinforcement learning. We consider these now introducing also a bit of material on “deep learning.” Deep learning is evolving so rapidly, that the discussion of deep learning may be somewhat dated.
One Numerical Realization of a Generalized Model of World Dynamics and Sustainable Development

We present a modification of the Forrester model of world dynamics. A new characteristic that describes the discontent with the development is introduced in each level of the model. It is shown that the proposed model may have a limit cycle.
COMPARATIVE STRESS ANALYSIS OF LINGUALIZED AND CONVENTIONAL BALANCED OCCLUSION SCHEMES IN A FULL-ARCH FIXED IMPLANT PROSTHESIS USING FINITE ELEMENT ANALYSIS

This study compares the biomechanical behavior of a mandibular full-arch fixed implant prosthesis with four implants under lingualized and conventional balanced occlusion schemes. The acrylic resin denture was supported by four titanium cylindrical implants and connected via a titanium prosthetic rectangular bar. Orthotropic material was used for the cortical and cancellous bones. The applied loadings were vertical and bilateral: 100N on first molar and 50N on first and second premolars each. For the lingualized balanced occlusion, the loadings were applied in central fossae of the posterior teeth, whereas for the conventional balanced occlusion the loadings were applied in central fossae and buccal cusps. The maximum von-Mises stresses for the lingualized and conventional balanced schemes were 301MPa and 25MPa, respectively, and were located at the neck of the posterior implants. In the denture teeth, the highest stress was located at the beginning of the cantilever extension. In the cortical bone, according to Tsai–Wu criterion, the failure index for the lingualized balanced occlusion was 1.10 and for the conventional balanced occlusion was 0.83. Thus, the conventional balanced occlusion demonstrated more favorable stress distribution in the implants and the cortical bone than the lingualized balanced occlusion.
Oliver’s Auteurs: The Cases of Lean and Polanski

As Juliet John writes, “Oliver Twist always has been, and always will be, an illegitimate text of mixed and impure origins.” This chapter foregrounds Oliver Twist’s status as a hybrid text – its impurity – to explore the divergent effects its adaptations have produced in the respective receptions and oeuvres of two prominent filmmakers: David Lean and Roman Polanski. In addition to complicating our understanding of the adaptation process, exploring the different ends to which Lean and Polanski adapt Oliver Twist emphasizes the multiple, even contradictory ways that prestige can be generated within a cultural economy. Moreover, considering the influence of Oliver Twist on the career arcs of these two filmmakers also offers a critique of auteurism by challenging the assertion that auteurs tend to eschew literary adaptations.
Genome-Wide Mapping of Decay Factor–mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4

The Ccr4 (carbon catabolite repression 4)-Not complex is a major regulator of stress responses that controls gene expression at multiple levels, from transcription to mRNA decay. Ccr4, a "core" subunit of the complex, is the main cytoplasmic deadenylase in Saccharomyces cerevisiae; however, its mRNA targets have not been mapped on a genome-wide scale. Here, we describe a genome-wide approach, RNA immunoprecipitation (RIP) high-throughput sequencing (RIP-seq), to identify the RNAs bound to Ccr4, and two proteins that associate with it, Dhh1 and Puf5 All three proteins were preferentially bound to lowly abundant mRNAs, most often at the 3' end of the transcript. Furthermore, Ccr4, Dhh1, and Puf5 are recruited to mRNAs that are targeted by other RNA-binding proteins that promote decay and mRNA transport, and inhibit translation. Although Ccr4-Not regulates mRNA transcription and decay, Ccr4 recruitment to mRNAs correlates better with decay rates, suggesting it imparts greater control over transcript abundance through decay. Ccr4-enriched mRNAs are refractory to control by the other deadenylase complex in yeast, Pan2/3, suggesting a division of labor between these deadenylation complexes. Finally, Ccr4 and Dhh1 associate with mRNAs whose abundance increases during nutrient starvation, and those that fluctuate during metabolic and oxygen consumption cycles, which explains the known genetic connections between these factors and nutrient utilization and stress pathways.
A Search for Colonial Histories: The Conquest by Yxta Maya Murray

Fernandez examines the significance of Murray’s juxtaposition of a colonial narrative of cross-cultural contact with a contemporary narrative of postcolonial deterritorialized and displaced communities. Focusing on magical indigenous characters, Murray produces a Borderland Narrative that moves across time and between intersecting accounts of oppression. She reinforces the idea of “polyphonic meaning” rather than a singular colonizing narrative; and by utilizing pre-Hispanic mythology as a foundational narrative, she nonviolently critiques and resists the overarching European colonial project.