cssi/SciSciGPT-SciSciNet huggingface dataset:
Prograde eclogite in the Gföhl Nappe, Czech Republic: new evidence on Variscan high‐pressure metamorphism

A layer of relict, high-temperature, prograde eclogite has been discovered within felsic granulite of the Gfohl Nappe, which is the uppermost tectonic unit in the Moldanubian Zone of the Bohemian Massif, the easternmost of the European Variscan massifs. Pressure-temperature conditions for eclogite (≥890 °C, 18.0 kbar) and felsic granulite (c. 1000 °C, 16 kbar) place early metamorphism of the polymetamorphic Gfohl crustal rocks within the eclogite facies, and preservation of prograde compositional zoning in small garnet grains in high-temperature eclogite requires very rapid heating, as well as cooling. Mantle-derived garnet and spinel–garnet peridotites are associated with the high temperature-high pressure crustal rocks in the Gfohl Nappe, and this distinctive lithological suite appears to be unique among European Phanerozoic orogenic belts, implying that tectonic processes during the late stages in evolution of the Variscan belt were different from those in the Caledonian and Alpine belts. The unusually high temperatures and pressures in Gfohl crustal rocks, mineralogical evidence for rapid heating and cooling, juxtaposition of lithospheric and asthenospheric mantle with crustal rocks, and widespread production of late-stage granites indicate that culmination of the Variscan Orogeny may have been driven by lithospheric delamination and asthenospheric upwelling.
Systematic implicationsofflavonoid patterns in Haplopappus segregates

Complex flavonoid patterns are correlated with primitive woody taxa and high base chromosome numbers among Haplopappus segregates. Variability among flavonoid complements supports the polyphyletic interpretation of the genus.
Support Vector Machines and Wavelet Packet Analysis for Fault Detection and Identification

This paper presents a data driven fault detection and identification (FDI) method using support vector machines (SVM) and the wavelet packet transform (WPT). The primary focus of this paper is to present a robust data driven fault diagnosis scheme. The investigated scheme has the capability to detect and identify faulty components of a given system through examination of its output due to a specified input. The use of the wavelet packet transformation serves to draw out those features of the output response which best characterize each of the fault classes for the various components. Support vector machines are used as the diagnosis phase to detect and isolate faults of a given system.
A DIGNITARY IN THE LAND? LITERARY REPRESENTATIONS OF THE AMERICAN RABBI

The Haskalah of the late eighteenth century, it is often observed, dealt a major blow to many traditional Ashkenazic institutions, including the rabbinate.2 Formerly extolled by their communities in nearly God-like superlatives-such as "Chief shepherd, a dignitary in the land ... Prince among princes in Torah and wisdom"3-rabbis became the object of trenchant criticism during this period.4 The maskilim, formerly denizens of the yeshivot, cast special aspersion on rabbis and their assertion of the authority of Jewish law, charging that the rabbinic insistence on stringencies and legal minutiae was the source of all that was wrong with Diaspora Jewish life. Much of the critique of the rabbinate targeted the culture of yeshiva learning that supported it; the maskilim promoted the study of philosophy, science, Hebrew literature, and the scientific study of Judaism. Often, this
Pittfalls of MRI measurement of white matter perfusion based on arterial spin labeling

Although arterial spin labeling (ASL) MRI has been successfully applied to measure gray matter (GM) perfusion in vivo, accurate detection of white matter (WM) perfusion has proven difficult. Reported literature values are not consistent with each other or with perfusion measured with other modalities. In this work, the cause of these inconsistencies is investigated. The results suggest that WM perfusion values are substantially affected by the limited image resolution and by signal losses caused by the long transit times in WM, which significantly affect the label. From gadolinium diethylenetriamine pentaacetic acid (Gd-DTPA) bolus-tracking experiments (N=6), it is estimated that the transit time can be several seconds long in deep WM. Furthermore, simulations show that even at a spatial resolution of 7 microl voxel size, contamination by the GM signals can exceed 40% of the actual WM signal. From 10-min long flow-sensitive alternating inversion recovery ASL (FAIR-ASL) measurements at 3T in normal subjects (N=7), using highly sensitive detectors, it is shown that single-voxel (7 mul) deep WM perfusion values have an signal-to-noise ratio (SNR) less than 1. The poor sensitivity and heterogeneous transit time limit the applicability of ASL for measurement of perfusion in WM.
Proliferating Cell Nuclear Antigen : A New Marker of Proliferation in Cancer

Proliferating cell nuclear antigen (PCNA) is the auxiliary protein of DNA polymerase δ It is induced in late G1 and S phases following mitotic stimulation of resting cells and is required for efficient DNA synthesis and cell cycle progression. Its expression in normal and malignant proliferating cells is related to proliferative activity. Because of the potential for substantial variability between proliferating cell populations with respect to the proportions of cells in G0 or G1, assays of PCNA can complement DNA analysis for assessment of proliferative activity in malignant cells and tissues. Data with respect to expression of PCNA in leukemia and in some solid tumors will be reviewed.
Generating knowledge of academic language among urban middle school students

A quasi-experimental study of a novel, cross-content area vocabulary intervention program called Word Generation showed significantly greater growth among 6th- to 8th-grade students in schools implementing the program than in comparison schools, on a curriculum-specific test. Furthermore, the language-minority students in the treatment, but not the comparison, schools showed greater growth than the English-only students. Improvement on the curriculum-specific test predicted performance on the Massachusetts Comprehensive Assessment System (MCAS) English language arts assessment, again only for students in the treatment schools. Recognizing the need to implement a more rigorous experimental study of this program, nonetheless we conclude that participation in the intervention, with its focus on deep reading, comprehension of current-events topics, productive classroom discussion, developing arguments, and producing persuasive essays, was a plausible contributor to student performance on the MCAS.
Insulin attenuates atrophy of unweighted soleus muscle by amplified inhibition of protein degradation

Unweighting atrophy of immature soleus muscle occurs rapidly over the first several days, followed by slower atrophy coinciding with increased sensitivity to insulin of in vitro protein metabolism. This study determined whether this increased sensitivity might account for the diminution of atrophy after 3 days of tall-cast hindlimb suspension. The physiological significance of the increased response to insulin in unweighted muscle was evaluated by analyzing in vivo protein metabolism for day 3 (48 to 72 hours) and day 4 (72 to 96 hours) of unweighting in diabetic animals either injected with insulin or not treated. Soleus from nontreated diabetic animals showed a similar loss of protein during day 3 (-16.2%) and day 4 (-14.5%) of unweighting, whereas muscle from insulin-treated animals showed rapid atrophy (-14.5%) during day 3 only, declining to just -3.1% the next day. Since fractional protein synthesis was similar for both day 3 (8.6%/d) and day 4 (7.0%/d) of unweighting in insulin-treated animals, the reduction in protein loss must be accounted for by a slowing of protein degradation due to circulating insulin. Intramuscular (IM) injection of insulin (600 nmol/L) stimulated in situ protein synthesis similarly in 4-day unweighted (+56%) and weight-bearing (+90%) soleus, even though unweighted muscle showed a greater in situ response of 2-deoxy-[3H]glucose uptake to IM injection of either insulin (133 nmol/L) or insulin-like growth factor-I (IGF-I) (200 nmol/L) than control muscle. These findings suggest that unweighted muscle is selectively more responsive in vivo to insulin, and that the slower atrophy after 3 days of unweighting was due to an increased effect of insulin on inhibiting protein degradation.
The effect of immediate constrained digital motion on the strength of flexor tendon repairs in chickens

Profundus tendon lacerations were repaired in the central toes of 216 chickens, and the digits were either immobilized in a cast or allowed immediate constrained motion in a tethering splint. The effect of digital motion on the early phases of tendon healing was investigated by comparing the rupture strengths of the two groups during the first 40 days after repair. The repairs in immobilized digits showed marked decreases in strength during the first 20 days, while the tendons in mobilized digits showed immediate and progressive gains in strength through the time intervals studied. By 5 days, the difference in strength between the two groups was significant ( p
HIV testing among individuals with a severe mental illness: review, suggestions for research, and clinical implications

Background. The prevalence of human immunodeficiency virus (HIV) is elevated among individuals with a severe mental illness (SMI). Because of the benefits of HIV testing, it is important for individuals with SMI to have routine access to testing. The goals of this review are: to summarize knowledge about HIV testing prevalence, correlates, and interventions among individuals with an SMI; to identify research needs; and to discuss clinical implications of the studies reviewed. Method. Literature searches were conducted using PsycINFO, PubMed, and Medline. Additional articles were obtained from reference lists of relevant articles. Results. Fewer than one-half of individuals with an SMI have been tested for HIV in the past year. Engaging in sex or drug risk behavior was the only consistent correlate of HIV testing. Interventions for promoting HIV testing among individuals with an SMI have not been well developed or evaluated. Conclusions. Research on HIV testing among individuals with an SMI is needed. Mental health settings may be opportune venues for HIV testing, even though providers face ethical challenges when implementing testing programs in these settings.
Physical planning of on-chip interconnect architectures

Interconnect architecture plays an important role in determining the throughput of meshed communication structures. We assume a mesh structure with uniform communication demand for communication. A multi-commodity flow (MCF) model is proposed to find the throughput for several different routing architectures. The experimental results reveal several trends: 1. The throughput is limited by the capacity of the middle row and column in the mesh, simply enlarging the congested channel cannot produce better throughput. A flexible chip shape provides around 30% throughput improvement over a square chip of equal area. 2. A 45-degree mesh allows 17% throughput improvement over 90-degree mesh and a 90-degree and 45-degree mixed mesh provides 30% throughput improvement. 3. To achieve maximum throughput on a mixed Manhattan and diagonal interconnect architecture, the best ratio of the capacity for diagonal routing layers and the capacity for Manhattan routing layers is 5.6. 4. Incorporating a simplified via model, interleaving diagonal routing layers and Manhattan routing layer is the best way to organize the wiring directions on different layers.
Simulation-based real-time scheduling: review of recent developments

With increased usage of computer monitoring of the factory has come increased industrial and academic interest in developing more science-based real-time scheduling techniques. Simulation, best known for its application during system design or modification, is also being considered for use on day-to-day scheduling problems. This paper reviews recent developments using simulation as a tool in real-time scheduling.
Evolving functions of endothelial cells in inflammation

Inflammation is usually analysed from the perspective of tissue-infiltrating leukocytes. Microvascular endothelial cells at a site of inflammation are both active participants in and regulators of inflammatory processes. The properties of endothelial cells change during the transition from acute to chronic inflammation and during the transition from innate to adaptive immunity. Mediators that act on endothelial cells also act on leukocytes and vice versa. Consequently, many anti-inflammatory therapies influence the behaviour of endothelial cells and vascular therapeutics influence inflammation. This Review describes the functions performed by endothelial cells at each stage of the inflammatory process, emphasizing the principal mediators and signalling pathways involved and the therapeutic implications.
Third-degree heart block associated with bupivacaine infusion following total knee arthroplasty. A case report.

Total knee arthroplasty is one of the most successful operations performed. Multiple modalities are utilized for pain management in the perioperative period. Regional anesthesia is a common, effective method associated with high patient satisfaction. It typically provides exceptional local pain control without the systemic side effects that have been associated with oral or parenteral narcotics. Alleviation of pain allows for earlier mobilization and potentially shorter hospital stays. However, continuous infusion of a long-acting local anesthetic is not without risk. Case reports of severe complications such as hypotension, arrhythmia, seizure, and cardiovascular collapse have been reported, but all involved intra-articular injections or a single injection of a large dose of anesthetic medication to attain a regional block1-6. We found no reports of arrhythmia in association with an indwelling catheter in patients who were receiving regional anesthesia. We present the case of a patient in whom a third-degree heart block developed in association with a continuous bupivacaine infusion through an indwelling femoral catheter. The patient was informed that data concerning the case would be submitted for publication, and she consented. ### History A seventy-eight-year-old woman who weighed 59 kg had a five-year history of progressive, debilitating, left knee pain that was most severe with walking, stair-climbing, and arising from a seated position. As nonoperative treatment had failed to provide relief, the decision was made to perform a total knee replacement. Her medical history included osteoarthritis of both knees, peptic ulcer disease, a cerebrovascular accident in 1993, and cirrhosis of the liver secondary to alcohol abuse. The patient had previously undergone a right total knee arthroplasty with no complications. Physical examination of the left lower extremity demonstrated a 20° valgus deformity and an arc of knee motion from 15° to 115°. Due to the known fact that the patient had liver …
Abstract IA12: Collaborators to the Sovereigns: Learning from history to make new chapters in research with American Indians and Alaska Natives

Purpose/Objective(s): Cancer death rates in the US have declined. However, this trend is not true for American Indians and Alaska Natives (AI/AN) where rates have remained unchanged. Further, AI/ANs have experienced the poorest five-year cancer survival rates of all racial and ethnic groups. The presentation will touch upon the historical traumas and contemporary resiliencies which have had influences on health behaviors, lifestyles, and the investigations of disparities among AI/AN Peoples and communities. The objectives will include 1) the movement of tribes exerting research sovereignty; 2) sharing the state of the science about bio-ethics in the landscapes of Indigenous Peoples; and 3) how cancer centers and academic institutions are becoming effective partners in the research process. Newsworthy exemplars of research in Indian Country will be shared. Materials/Methods: This multifaceted presentation will share 1) research sovereignty through a tribal protocol and recommendations from the US Health and Human Services, AI/AN Research Advisory Council; 2) experiences gained from work with cancer and bio-ethics projects with an AI/AN urban population; 3) how legal cases such as Havasupai vs. Arizona State University have shaped new chapters in research with AI/AN Nations and lastly, 4) a showcase of challenges and resiliencies of Native Nations and their response to various types of health disparity research. Summary: The literature discussed provides a foundation for understanding cancer and health disparity research from a historical perspective that should inform future practices. This includes the importance of building relationships, community based participation, tribally driven research agendas, the sharing of sovereign philosophies, and the highlighting of resiliencies. Conclusions: The development of respectful relationships is important to solidify trust in AI/AN communities where researchers intend to collaborate. This is especially true in sensitive research fields such as genetics, bio-specimen, and cancer and health disparity clinical trials. Community based participatory research should be implemented from the beginning with the community in an effort to jointly build research agendas that are both scientifically novel and beneficial to AI/AN landscapes. Citation Format: Rodney C. Haring. Collaborators to the Sovereigns: Learning from history to make new chapters in research with American Indians and Alaska Natives. [abstract]. In: Proceedings of the Seventh AACR Conference on The Science of Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; Nov 9-12, 2014; San Antonio, TX. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2015;24(10 Suppl):Abstract nr IA12.
Fast Meson Interactions in Nuclear Emulsions. I. π - Mesons

${\ensuremath{\pi}}^{+}$ mesons produced in the exterior proton beam of the Berkeley cyclotron are bent by an auxiliary magnet and detected in Ilford G5 emulsions. These mesons are studied in the same way as were the ${\ensuremath{\pi}}^{\ensuremath{-}}$ mesons in Part I of this experiment. Extra care is taken to eliminate protons from the data and a special technique is developed to make more efficient small angle scattering measurements. The average initial energy, 45.5 Mev, is slightly higher than that of the ${\ensuremath{\pi}}^{\ensuremath{-}}$ mesons, and the spread in energy is greater. Less than 18 percent of observed track is less than 30 Mev and 98 percent of it is over 22 Mev.No disappearances are found over the 902 cm of track. Fewer are expected than were found in Part I, since the average number of charged prongs is greater for ${\ensuremath{\pi}}^{+}$ induced stars than for ${\ensuremath{\pi}}^{\ensuremath{-}}$. No inelastic scatters are found among the 5 scatters greater than 30\ifmmode^\circ\else\textdegree\fi{}. Though the star frequency is the same as in the previous experiment, the frequency for scatters is significantly lower, a fact which is not explained by the slightly higher energy. A statistical upper bound on the cross section for ${\ensuremath{\pi}}^{+}$ scattering on hydrogen is obtained as 2.3\ifmmode\times\else\texttimes\fi{}${10}^{\ensuremath{-}26}$ ${\mathrm{cm}}^{2}$.
Cancer of the lung. A preventable disease.

Although increasing in incidence and largely both incurable and fatal, lung cancer can be prevented by abstinence from smoking. The author presents confirming statistics.
Simulated Attention-Tracking Methodologies: An Examination of Measurement Efficacy

ABSTRACTThis study introduces and examines a simulated attention-tracking methodology as an emerging technique to improve the study of in-store shopper behavior and decision making. To assess the viability of this new methodology, we examine its efficacy in producing consumer behavior data consistent with results predicted by the marketing literature. Empirical data across five grocery categories are used to examine the influence of personal, product, and situational differences on external information search. Findings show that the attention-tracking methodology is able to demonstrate expected results in almost all cases. The methodology is also able to provide a more complete view of external information search through tracing the observed search behavior preceding decision making. This proof of methodology responds directly to calls in the marketing and retailing literature to test new and emerging methodologies in support of research on in-store marketing and shopper behavior. Findings also provide ma...
Chylomicron remnant uptake by enterocytes is receptor dependent

During glyceryl trioleate absorption in the rat, mucosal triacylglycerol (TG) fatty acids have been shown to consist of only 71% exogenous oleate. Chylomicron remnants are enriched with endogenous TG fatty acids, compared with their parent chylomicrons, which consist primarily of exogenous TG fatty acids. Because enterocytes have the apolipoprotein B-100/E receptor, this study was directed at determining whether the cells can take up and metabolize chylomicron remnants and, if so, whether this was receptor mediated. Isolated enterocytes were incubated with purified 3H-labeled chylomicron remnants. The remnants were shown to be taken up by the basolateral membrane, not the apical membrane. Remnant uptake was proportional to time and number of enterocytes, and saturation kinetics were observed. Nonradiolabeled remnants, human low-density lipoprotein (LDL), anti-LDL receptor antibody, and receptor-associated protein, an LDL-related receptor inhibitor, were all shown to compete for or reduce 3H-remnant uptake. Remnants taken up by the enterocytes could not be removed on incubation with excess human LDL. Uptake was shown to be greatest in the villus tips of the proximal intestine. These studies suggest that enterocytes take up chylomicron remnants by a receptor-mediated process from their basolateral membranes and that the remnants could provide a source of endogenous TG fatty acids for the enterocytes.
Radiation Visible and Invisible

What do we mean by the invisible Universe? Simply those objects in space that emit types of electromagnetic radiation to which the human eye is insensitive. These radiations include radio waves, infrared and ultraviolet radiation, and x rays and gamma rays. Each of these different kinds of radiation travels at the velocity of light — 300,000 kilometers per second — just as does visible light itself, which is simply another kind of radiation.
Role of G-Proteins in Mechanical Signal Transduction

Cells have highly specialized forced sensing mechanisms such as those involved in hearing and touch which can convert a mechanical stimulus into electrical and biochemical responses. Fluid flow itself is another such stimulus that exists in the cellular environment. Indirect evidence suggests that flow regulation of vascular tone via the endothelium and smooth muscle cells involves mechanical signal transduction via G proteins. Human Umbilical Vein Endothelial cells (hUVECs) grown on glass slides were subjected to fluid flow in parallel plate flow chambers. Fluid shear-induced GTP binding in hUVECs was assayed by preincubating the cells with a GTP photoreactive analogue, 8-azido GTP (α-32p) and subjecting to UV crosslinking after fluid flow (10 dynes/cm2) for 10 sec. Autoradiographic analysis of these cells lysate show a 42 kDa protein being labeled by GTP upon flow stimulation. Further this protein was identified with anti Gα subunits Gαq and Gαi3 may be involved in the flow induced signal transduction pathway in endothelial cells. In other supporting experiments, Gproteins purified from bovine brain were reconstituted into PE:PS liposomes and subjected to fluid shear. There was an increase in Gprotein mediated GTP hydolysis upon the onset of shear. These experiments suggest the involvement of Gproteins as mechanochemical signal transducers. This work is supported by HL40696-07.
Cognitive Effects of Anticonvulsants

The neuropsychological effects of carbamazepine, phenobarbital, and phenytoin in 15 patients with partial complex epilepsy were investigated at the Department of Neurology, Medical College of Georgia, Augusta, GA.
Initial Assessment of the Correlation Between Atmospheric Conditions and Photovoltaic Energy Generation at The University of Toledo

Monitoring, collection, and analysis of atmospheric data for power generation from photovoltaic (PV) systems provides essential information about performance under a wide range of atmospheric conditions. Global installed PV generating capacity continues to grow (currently > 100 GW) at a high rate (average of >50% the past 5 years); analysis of detailed PV system performance will play an increasingly important role in forecasting PV production, enabling minimization of complementary non-renewable energy production and reduction in corresponding greenhouse gas emissions. In this report, collected data is analyzed to better understand how module temperature, air temperature, and irradiance determine a PV system’s energy production. Such knowledge supports improved PV energy production forecasting. The University of Toledo’s CdTe array shows a smaller temperature coefficient (-0.07 %·°C -1 ), indicating decreased system performance at elevated module temperature) than was reported in First Solar’s research study (-0.20 %·°C -1 ). Possible explanations for this behavior are presented.
Competition as cooperation

Games have a complex, and seemingly paradoxical structure: they are both competitive and cooperative, and the competitive element is required for the cooperative element to work out. They are mecha...
Single-institution experience with FOLFIRINOX in advanced pancreatic cancer (PC).

330 Background: FOLFIRINOX provides clinically significant benefit in advanced PC compared to gemcitabine (Conroy et al. New Engl J Med 2011;364:1817). Despite superior efficacy, toxicities have te...
Solar Event Classification Using Deep Convolutional Neural Networks

The recent advances in the field of neural networks, more specifically deep convolutional neural networks (CNN), have considerably improved the performance of computer vision and image recognition systems in domains such as medical imaging, object recognition, and scene characterization. In this work, we present the first attempt into bringing CNNs to the field of Solar Astronomy, with the application of solar event recognition. With the objective of advancing the state-of-the-art in the field, we compare the performance of multiple well established CNN architectures against the current methods of multiple solar event classification. To evaluate the effectiveness of deep learning in the solar image domain, we experimented with well-known architectures such as LeNet-5, CifarNet, AlexNet, and GoogLenet. We investigated the recognition of four solar event types using image regions extracted from the high-resolution full disk images of the Sun from the NASA’s Solar Dynamics Observatory (SDO) mission. This work demonstrates the feasibility of using CNNs by obtaining improved results over the conventional pattern recognition methods used in the field.
Study of Layer Formation During Droplet-Based 3D Printing of Gel Structures

Additive manufacturing, also known as three-dimensional (3D) printing, is an approach in which a structure may be fabricated layer by layer. For 3D inkjet printing, droplets are ejected from a nozzle and each layer is formed droplet by droplet. Inkjet printing has been widely applied for the fabrication of 3D biological gel structures, but the knowledge of the microscale interactions between printed droplets is still largely elusive. This study aims to elucidate the alginate layer formation process during drop-on-demand inkjet printing using high speed imaging and particle image velocimetry. Droplets are found to impact, spread, and coalesce within a fluid region at the deposition site, forming coherent printed lines within a layer. Interfaces are found to form between printed lines within a layer depending on printing conditions and printing path orientation. The effects of printing conditions on the behavior of droplets during layer formation are discussed and modeled based on gelation dynamics, and recommendations are presented to enable controllable and reliable fabrication of gel structures.Copyright © 2017 by ASME
Law and Psychology Grows Up, Goes Online, and Replicates

Over the last 30 years, legal scholars have increasingly deployed experimental studies, particularly hypothetical scenarios, to test intuitions about legal reasoning and behavior. That movement has accelerated in the last decade, facilitated in large part by cheap and convenient Internet participant recruiting platforms like Amazon Mechanical Turk. The widespread use of online subjects, a practice that dramatically lowers the barriers to entry for experimental research, has been controversial. At the same time, the field of experimental psychology is experiencing a public crisis of confidence widely discussed in terms of the “replication crisis.” At present, law and psychology research is arguably in a new era, in which it is both an accepted feature of the legal landscape and also a target of fresh skepticism. The moment is ripe for taking stock. In this article, we bring an empirical approach to these problems. Using three canonical law and psychology findings, we document the challenges and the feasibility of reproducing results across platforms. We evaluate the extent to which we are able to reproduce the original findings with contemporary subject pools (Amazon Mechanical Turk, other national online platforms, and in‐person labs). We partially replicate all three results, and show marked similarities in subject responses across platforms. In the context of the experiments here, we conclude that meaningful replication requires active intervention in order to keep the materials relevant and sensible. The second aim is to compare Amazon Mechanical Turk subjects to the original samples and to the replication samples. We find, consistent with the weight of recent evidence, that the Amazon Mechanical Turk samples are reasonably appropriate for these kinds of scenario studies. Subjects are highly similar to subjects on other online platforms and in‐person samples, though they differ in their high level of attentiveness. Finally, we review the growing replication literature across disciplines, as well as our firsthand experience, to propose a set of standard practices for the publication of results in law and psychology.
The Art of Faking a Smile

As I write this essay, it is my hope to bring the voices of mental illness out from their silence. Through (re)writing my past, I describe my experiences living with depression, attention deficit disorder, and anxiety. This essay navigates moments within my life where “disruptions” have occurred—encounters with people where actions come to be understood as hurtful or incompetent (Frank, 2000).
Pediatric emergency department visits for pedestrian and bicyclist injuries in the US.

Despite reductions in youth pedestrian and bicyclist deaths over the past two decades, these injuries remain a substantial cause of morbidity and mortality for children and adolescents. There is a need for additional information on non-fatal pediatric pedestrian injuries and the role of traumatic brain injury (TBI), a leading cause of acquired disability. Using a multi-year national sample of emergency department (ED) records, we estimated annual motorized-vehicle related pediatric pedestrian and bicyclist (i.e. pedalcyclist) injury rates by age and region. We modeled in-hospital fatality risk controlling for age, gender, injury severity, TBI, and trauma center status. ED visits for pediatric pedestrian injuries declined 19.3% (95% CI 16.8, 21.8) from 2006 to 2012, with the largest decreases in 5-to-9 year olds and 10-to-14 year olds. Case fatality rates also declined 14.0%. There was no significant change in bicyclist injury rates. TBI was implicated in 6.7% (95% CI 6.3, 7.1) of all pedestrian and bicyclist injuries and 55.5% (95% CI 27.9, 83.1) of fatalities. Pedestrian ED visits were more likely to be fatal than bicyclist injuries (aOR = 2.4, 95% CI 2.3, 2.6), with significant additive interaction between pedestrian status and TBI. TBI in young pedestrian ED patients was associated with a higher risk of mortality compared to cyclists. There is a role for concurrent clinical focus on TBI recovery alongside ongoing efforts to mitigate and prevent motor vehicle crashes with pedestrians and bicyclists. Differences between youth pedestrian and cycling injury trends merit further exploration and localized analyses, with respect to behavior patterns and interventions. ED data captures a substantially larger number of pediatric pedestrian injuries compared to crash reports and can play a role in those analyses.
Author Correction: Comprehensive molecular profiling of lung adenocarcinoma

In Supplementary Table 7 of this Article, the iCLUSTER output column contained incorrected cluster labels. This table has been corrected online. Corrected online 08 October 2014 - The surname of author Kristen Rodgers was misspelled ‘Rogers’. This has been corrected online.
Experimental Evaluation of Some Selected Lightweight Superinsulation for Space Vehicles

The use of high-energy cryogenic fuels has imposed demands for effective design and application of superinsulation for advanced tank designs. The high effectiveness of multilayer superinsulations is achieved by a series of’ radiation shields of low emissivity. The shields may be separated by insulating spacers under a pressure below 10-5 mm Hg absolute. During ground hold and boost, the insulation is exposed to the atmosphere unless it is sufficiently shrouded. This paper will not discuss these transient conditions, but rather will be concerned only with the subsequent space performance.
Preliminary experimental study on cold fusion using deuterium gas and deuterium plasma in the presence of palladium

The authors describe a series of experiments using deuterium gas and deuterium plasma in the presence of palladium designed to observe the possibility of cold fusion. Two kinds of preliminary experiments were recently performed. One involved the diffusion of deuterium gas into paladium. The gas was cooled by liquid nitrogen, and then the temperature was permitted to rise to room temperature, going from near -34 to 19{sup 0}C (-30 to 67{sup 0}F) in 75 min. A spherical lithium neutron detector, 21 cm from the palladium gave an audible indication of neutron levels approximately equal to, but above, background. A second experiment used a deuterium ion beam (1 keV) that bombarded a palladium target.
Some aspects of energy coupling by mitochondria.

This paper will review some recent developments and trends of thought on the energetics, mechanism, and dynamics of electron transport and oxidative phosphorylation, as well as some aspects of the interplay between the mitochondrial and cytosolic compartments of cells basic to an understanding of metabolic regulation.
Patient Portal Use in Diabetes Management: Literature Review.

Background Health information technology tools (eg, patient portals) have the potential to promote engagement, improve patient-provider communication, and enhance clinical outcomes in the management of chronic disorders such as diabetes mellitus (DM). Objectives The aim of this study was to report the findings of a literature review of studies reporting patient portal use by individuals with type 1 or type 2 DM. We examined the association of the patient portal use with DM-related outcomes and identified opportunities for further improvement in DM management. Methods Electronic literature search was conducted through PubMed and PsycINFO databases. The keywords used were "patient portal*," "web portal," "personal health record," and "diabetes." Inclusion criteria included (1) published in the past 10 years, (2) used English language, (3) restricted to age ≥18 years, and (4) available in full text. Results This review included 6 randomized controlled trials, 16 observational, 4 qualitative, and 4 mixed-methods studies. The results of these studies revealed that 29% to 46% of patients with DM have registered for a portal account, with 27% to 76% of these patients actually using the portal at least once during the study period. Portal use was associated with the following factors: personal traits (eg, sociodemographics, clinical characteristics, health literacy), technology (eg, functionality, usability), and provider engagement. Inconsistent findings were observed regarding the association of patient portal use with DM-related clinical and psychological outcomes. Conclusions Barriers to use of the patient portal were identified among patients and providers. Future investigations into strategies that engage both physicians and patients in use of a patient portal to improve patient outcomes are needed.
Field identification of Eriogonum corymbosum vars. nilesii and aureum (Polygonaceae)

Eriogonum corymbosum vars. nilesii and aureum have been difficult to distinguish in the field due to their phenotypic similarities. Greater understanding of the ranges of these two varieties has been demonstrated by genetic analyses over the past decade. However, field identification remains problematic, and current dichotomous keys do not provide reliable traits, or trait combinations, to enable botanists to confidently distinguish these two taxa. We examined morphological characters among individuals from six populations of E. corymbosum (three of var. nilesii and three of var. aureum ). We found significant differences between these two varieties in petiole length, leaf length, and the ratios of leaf-blade length to petiole length and leaf-blade width to petiole length. We also found qualitative differences in adaxial leaf color and inflorescence-stem pubescence. Petiole length was the significantly different trait with the least overlap between varieties, making it practical for distinguishing between E. corymbosum vars. nilesii and aureum in the field. Moreover, these six trait differences lend further support to genetic findings in previous studies that confirmed the existence of these two taxa and demonstrated their limited ranges and rarity.
Earable -- An Ear-Worn Biosignal Sensing Platform for Cognitive State Monitoring and Human-Computer Interaction (demo)

Cognitive state monitoring is crucial for neurological disorders such as epilepsy, narcolepsy, insomnia, and many other human health concerns. The capability to continuously monitor an individual wearing the device and accurately provide early warnings of seizures or narcolepsy sleep attacks would be game-changing for these disorders. Beyond human health, complete hand-free/voice-free human-computer interaction is desirable for privacy-sensitive use cases or people with disabilities. To achieve this goal, we propose Earable, an ear-worn biosensing platform for cognitive state quantification and human-computer interaction. Earable can capture biosignal including brain waves activities, eyes movements, and facial muscle contractions from the back of the ears. Its form factor is convenient to use in everyday life. In this demo, we show two use cases for our Earable platform. First, as an example of cognitive state monitoring, our system plays relaxing music and dims the light when the user is trying to relax or sleep by detecting alpha and beta waves generated by the brain. Second, as an example of human-computer interaction, our system controls a drone with eye movements and facial muscle activity.
Non-prescription cannabis use for symptom management amongst women with gynecologic malignancies.

Abstract Objectives To evaluate interest in and patterns of use of non-prescription cannabis products for symptom management amongst gynecologic cancer patients living in states with legal access to medical and recreational marijuana. Methods Cross-sectional study using a novel 35-question survey distributed to women diagnosed with gynecologic cancer within two academic centers in California and Colorado. The survey queries demographic and disease traits, and both objective and subjective issues surrounding use of cannabis products for symptom management. Surveys were distributed to patients actively receiving treatment or under surveillance. Results Enrollment began July 16, 2018 and was completed December 1, 2018. Survey return rate was 52.7%. A total of 225 participants met inclusion criteria. Sixty-two percent reported that they have used or would be interested in using cannabis products for symptom management; 60 (26.7%) are using non-prescription cannabis for treatment of cancer related symptoms, and 80 (35.6%) are interested in using cannabis derivatives under direction of their oncologist. Reasons cited for use of cannabis included: pain control (n = 41, 68.3), insomnia (n = 33, 55.0%), anxiety (n = 29, 48.3%), nausea (n = 26, 43.3%), and appetite stimulation (n = 21, 35.0%). Of the women using cannabis products, almost half report decreased prescription narcotic use after initiation of cannabis products (n = 27, 45.0%). Conclusions Women with gynecologic cancer report a strong interest in the use of non-prescription cannabis products for management of cancer-related symptoms. Practitioners in the field of gynecologic oncology should be aware of the frequency of use of non-prescription cannabis amongst their patients as well as the growing desire for guidance about the use of cannabis derivatives. A substantial number of patients report decreased reliance on opioids when using cannabis derivatives for pain control.
Influencing the Behavioral Responses of Players in an Interactive Narrative Game through Music and Arousal Congruency

Music has been shown to influence the behavioral responses of individuals in real-world scenarios, but little research exists on the effects that music has on the in-game behaviors of video game players. A song can be rated in terms of the level of arousal, or emotional intensity, it incites, and this study explores how music of various arousal ratings can be used to influence players’ choices in an interactive narrative role-playing game. We hypothesized that high-arousal music would influence players to exhibit avoidance behaviors in-game, and that low-arousal music would influence players to exhibit social behaviors. Experimentation showed that players were statistically significantly more likely to make avoidance behavior choices when high-arousal music was played. These findings are the first step into understanding how music can be used by game developers to influence player behaviors in interactive narrative games.
Use of Medical Assistants in Blood & Marrow Transplant Program Outpatient and Inpatient Setting

Topic Significance & Study Purpose/Background/Rationale A Blood & Marrow Transplant [BMT] program incorporated Medical Assistants [MA's] onto the core clinical teams to perform essential functions. Their role augments interdisciplinary care coordination of ancillary and support services. Methods, Intervention, & Analysis MA were assigned onto interdisciplinary teams, typically consisting of a Medical Oncologist, Advanced Practice Providers, and Transplant Nurse Coordinators. Our MA's also work in conjunction with and as an extension of our Social Work team. Under the guidance of this team, the MA carries out functions including but not limited to: scheduling patients, appointments for visits, testing, referrals, telephone calls, and medications. Findings & Interpretation The addition of MAs onto the clinical teams alleviates workloads for the Transplant Coordinators, allowing their focus to shift to a more patient-centered care model. With the further development of oral chemo and targeted therapies, MAs can spend time working on initiating these therapies and addressing barriers. These therapies typically require insurance prior authorization or applications for patient assistance programs for unaffordable out-of-pocket. Often, MAs help provide these services for patients that are also admitted. This frees up nurses to focus on direct patient issues. Discussion & Implications The complexity of the BMT environment necessitates innovation. Utilizing MAs in this environment streamlines processes to provide comprehensive healthcare to our patients. Development of the MAs in this program leans on the full scope of their practice, while requiring more focused, specialized professional development. With the success of their integration in the outpatient environment, their unique skillset may present an opportunity to help with inpatient care coordination.
A Study of Secondary School Students’ Participation in a Novel Course on Genomic Principles and Practices

This paper presents the design, development, and validation of a study among secondary school students’ participation in a novel course on genomic principles and practices by analyzing and documenting evidence of their participation, and educational outcomes, in a novel course on genomic principles and practices. A mixed methods approach, using qualitative and quantitative methods, was used to address three research questions. 1) Based on affective evidence, how did secondary school students perceive and critically judge, content topics learned in a course on modern genomic principles and practices? 2) Based on cognitive evidence, how much of the content did secondary school students learn when they participated in a course on modern genomic principles and practices? 3) Using individual interview evidence, what are the major perceptions that the secondary school students expressed throughout the duration of the course? The participants were provided an opportunity to comment on the course through individual and collaborative interviews, in order to find out to what extent they perceived the course to be interesting and challenging. Future inquiry expanding from this research would help to establish the foundational pathway for designing a more inclusive genomics curriculum. In conclusion, the course offered real-life/real-world applications that encourage all students to conceptualize genomics, human health, diseases, medicine, ethics, beliefs, research, and careers.