cssi/SciSciGPT-SciSciNet huggingface dataset:
Angiotensin-1 receptor autoantibodies: A role in the pathogenesis of preeclampsia?

Preeclampsia is a pregnancy-specific disorder that presents major health problems for mothers and their babies. It is a major cause of maternal mortality, especially in developing countries, where it may account for 80% of maternal deaths.1 Even in developed countries, perinatal mortality is increased 5-fold. The last figure is especially tragic. Many of these infant deaths are secondary to iatrogenic prematurity, because the management remains as it has for the last 100 years (early delivery to terminate the process). Understandably, preeclampsia has been a major target of research to improve pregnancy outcome, yet it remains an enigmatic “disease of theories.” Nonetheless, in the last 10 years, an approach to understanding the disorder that addresses features other than simply the accompanying hypertension has rapidly accelerated understanding.2 In this issue of Circulation , Dechend and colleagues3 present another in their fascinating series of observations demonstrating that preeclamptic women manifest agonistic antibodies to angiotensin-1 (AT1) receptors. They demonstrate that these antibodies have the capability to activate the production of tissue factor by vascular smooth muscle cells in vitro. How does this observation fit into emerging concepts of the pathogenesis of preeclampsia? Eclampsia was described nearly 2000 years ago as seizures occurring during pregnancy that abated with delivery. It was not until the turn of this century that it was recognized that increased blood pressure and proteinuria accompanied, and in most cases preceded, eclampsia, hence “preeclampsia.”4 With this recognition, it was rapidly evident that these signs, even unaccompanied by seizures, signaled a disorder that could rapidly progress to maternal and fetal morbidity and mortality. Despite the value of these signs in aiding in recognition of the syndrome, it is abundantly evident that preeclampsia is more than “pregnancy-induced hypertension.” The pregnant woman with preeclampsia manifests alterations in many organ systems. …
Alcohol use among U.S. Muslim college students: risk and protective factors

Drinking behavior among Muslim college students in the United States is unknown. To obtain estimates and examine risk factors, the authors conducted secondary data analysis of the public access database from the 2001 Harvard School of Public Health College Alcohol Study. Two variables were associated with drinking-religious activities, which were protective against drinking, and parental approval of drinking, which was a risk factor for drinking. Although American Muslim students had a low rate of drinking in the past year (46.6%) compared to their U.S. college counterparts, they had a higher rate of alcohol consumption compared to their counterparts in predominately Muslim countries.
Showdown at Catron: Cows, Wolves, and the Ecology of Public Lands Policies

Political landscapes and natural landscapes interact in an ecological process that produces public lands policies. These policies evolve as the landscapes change. This ever-changing process is illustrated by the conflict in western New Mexico over the reintroduction of the endangered Mexican gray wolf. As the interests of wolf advocates and wolf opponents collide, particularly in Catron County, wolf release, relocation, and removal policies develop; the power and roles of local, state, and federal agencies shift; the skill, effectiveness, and technical sophistication of organized interests change; and the values and preferences held by the public evolve. This article examines this ecological public lands policymaking process through the showdown in Catron County.
The football brand dilemma

Brands symbolize our market-dominated, globalizing world. Football brands are particularly well suited for an economy of attention where branded goods are worth more because of their connection to abstract ideas. Football is media friendly, and, in its current incantations, corporate friendly. While football teams are bound to particular places such as Manchester or Madrid, they garner massive global TV audiences that dwarf the in-stadium crowd. The ambivalent relationship between a football team and a place is a hallmark of our times. Football teams are community goods – they require people to give them value and meaning, but what people and where? What happens when fans attempt to go from symbolic to real owners of a team? The mutiny of a group of Lazio fans serves as an illustration of the tension between the performance of fandom and the market logics of branding.
Going International: Accounting and Auditing Standards

The worldwide movement toward international standards for financial reporting and for auditing will have a significant impact on the work of corporate accountants and internal auditors. Across countries, accounting standards and auditing standards are different as a result of unique cultural, political, legal, and economic factors. Ongoing efforts to harmonize accounting and auditing standards are expected to benefit economic activity in nations around the world. This article examines the role of international accounting and auditing standards in today's global economy. A brief history of the International Accounting Standards Board (IASB) is provided, along with challenges to using the International Financial Reporting Standards (IFRS) issued by the IASB. An example balance sheet is provided that shows how IFRS results can differ from U.S. generally accepted accounting principles. A brief history of the International Auditing and Assurance Standards Board (IAASB) is provided, along with current developments regarding the International Standards on Auditing (ISA) issued by the IAASB.
A New Species of Flea from the Field Mouse, Baiomys Taylori

A large series of an apparently new flea has been taken from the field mouse, Baiomys taylori , in Lavaca County, Texas, in connection with an extensive murine typhus research program being conducted there by the Texas State Department of Health and the United States Public Health Service. Considering the small size of the Baiomys , the mice were heavily infested with this flea. During March and April, 1946, eighty-one fleas were combed from twenty-one of these mice.
Uptake of selenium-75 by PHA-stimulated lymphocytes : Effect on glutathione peroxidase.

To determine which of a variety of inorganic and organic selenium compounds could best stimulate glutathione peroxidase, human lymphocytes were cultured with a number of selenium sources. The phytohemagglutinin-transformed lymphocytes were cultured in the presence of75Se bound to serum proteins (25% v/v) or 10−7 M concentrations of [75Se]-selenite, [75Se]-selenate, [75Se]-selenocystine, and [75Se]-selenomethionine. Organic forms of selenium were taken up in preference to inorganic forms. Control cultures, from which exogenous selenium had been omitted, showed a decreased level of glutathione peroxidase activity at the end of a 4 d culture period. Of the Se sources tested, [75Se]-selenocystine and [75Se]-labeled fetal calf serum proteins increased enzyme activity significantly, 79 and 47%, respectively, but selenite increased activity only by 7%. These results indicate that selenium from the two organic sources is most readily available for glutathione peroxidase synthesis.
Distributions in a class of Poissonized urns with an application to Apollonian networks

We study a class of Polya processes that underlie terminal nodes in a random Apollonian network. We calculate the exact first and second moments of the number of terminal nodes by solving ordinary differential equations. These equations are derived from the partial differential equation governing the process. In fact, the partial differential equation yields a stochastic hierarchy of moment equations, which can be bootstrapped to get higher moments from the equations that have been solved for lower moments. We also show that the number of terminal nodes, when appropriately scaled, converges in distribution to a gamma random variable via the method of moments. The asymptotic results can be obtained using classic methods of branching processes. The manuscript explores the potential of an alternative method capable of producing exact moments and rates of convergence.
NEWTON'S METHOD, CIRCLE MAPS, AND CHAOTIC MOTION

On considere la methode de Newton en relation avec le probleme de l'iteration de polynomes et la determination des zeros
Special Issue on Secured Communication in Wireless and Wired Networks

The emergence of the Internet of Things (IoT) has enlarged the network scope even in daily life now as many household items are being served or connected. Due to such infiltration of networking, th...
A Discussion on Standardization of Electric Vehicle's Charging Coupler

Charging facility with unified charging coupler is the prerequisite for promotion and application of electric vehicles,and the standardization of charging coupler is the foundation to guarantee the safety and inter-changability during charging process.Firstly,the development and current situation of foreign charging coupler are introduced.Then,considering the actual situation of China's power grid and the requirement of electric vehicles'application,the application and technical details of domestic coupler,such as the safety of the coupler,the functions of the terminal,interaction with the grid,are briefly introduced.Finally,the future development of charging coupler is prospected.
Clinical Effect Study of Children with Encephalopathy Sequelae Treated with Hyperbaric Oxygen Therapy

Objective:To explore the clinical effect of hyperbaric oxygen therapy in children with encephalopathy sequelae.Methods:100 cases admitted in our hospital in January 2009 to December 2011 were selected and in accordance with the random number table were randomly assigned to the treatment group(50 cases) and control groups(50 cases).Control group used conventional drug therapy on the basis of acupuncture and moxibustion therapy;treatment group on the basis of conventional drug treatment added hyperbaric oxygen therapy.After the end of course,comparison of curative effect on two groups of patients was made.Results:Total efficiency of the treatment group(98%) was significantly higher than that of the control group(88%),with significant differences(P0.05).Conclusion:Hyperbaric oxygen in the treatment of infantile viral encephalopathy sequelae has good curative effect,and it is worthy of clinical applicaltion.
Reduction Cystoplasty in the Prune Belly Syndrome: A Long-Term Followup

AbstractThe role of reduction cystoplasty in the management of severe prune belly syndrome is controversial. From 1973 to 1990, 11 boys with severe prune belly syndrome underwent comprehensive urinary tract reconstruction, including overlapping reduction cystoplasty. Followup ranged from 1.5 to 18 years and 6 boys are now older than 18 years. Nine had sepsis or progressive renal failure as neonates; 7 had upper tract diversion as an initial procedure, of whom 2 have chronic renal failure. Currently 9 boys are voiding, including 1 who could not void preoperatively, with less than 50cc residual after double or triple voiding. One boy underwent transplantation to an ileal conduit and 1 continues on intermittent catheterization. In the 9 cases in which bladder volume data were available average reduction in volume at operation was 52%. At an average of 7.7 years later (range 1.5 to 14) bladder volumes corrected for age were essentially unchanged or greater than corrected preoperative volumes. Since reflux was...
State-aware Network Access Management for Software-Defined Networks

OpenFlow, as the prevailing technique for Software-Defined Networks (SDNs), introduces significant programmability, granularity, and flexibility for many network applications to effectively manage and process network flows. However, because OpenFlow attempts to keep the SDN data plane simple and efficient, it focuses solely on L2/L3 network transport and consequently lacks the fundamental ability of stateful forwarding for the data plane. Also, OpenFlow provides a very limited access to connection-level information in the SDN controller. In particular, for any network access management applications on SDNs that require comprehensive network state information, these inherent limitations of OpenFlow pose significant challenges in supporting network services. To address these challenges, we propose an innovative connection tracking framework called STATEMON that introduces a global state-awareness to provide better access control in SDNs. STATEMON is based on a lightweight extension of OpenFlow for programming the stateful SDN data plane, while keeping the underlying network devices as simple as possible. To demonstrate the practicality and feasibility of STATEMON, we implement and evaluate a stateful network firewall and port knocking applications for SDNs, using the APIs provided by STATEMON. Our evaluations show that STATEMON introduces minimal message exchanges for monitoring active connections in SDNs with manageable overhead (3.27% throughput degradation).
Correlation of the effects of bretylium, guanethidine, and N,N-diisopropyl-N'-isoamyl-N'-diethylaminoethylurea (P-286) on the H+ electrochemical gradient across the chromaffin granule membrane and on chromaffin granule function.

N,N-Diisopropyl-N9-isoamyl-N9-diethylaminoethylurea (P-286) (0.03-0.3 mM) reduced the ATP, Mg2+-induced electrical potential across the chromaffin granule membrane, inhibited ATP, Mg2+-dependent catecholamine uptake into chromaffin granules, and inhibited carbachol-induced secretion from cultured bovine chromaffin cells. P-286 did not alter the intragranular pH. Bretylium and guanethidine did not alter the H+ electrochemical gradient across the chromaffin granule membrane and did not alter the ATP, Mg2+-induced catecholamine uptake into chromaffin granules. The uptake of bretylium, a quaternary ammonium compound, into chromaffin granules responded to changes in membrane potential in a qualitatively similar manner to that of the lipid-soluble cation triphenylmethylphosphonium cation (TPMP+). This study provides further evidence that catecholamine uptake into chromaffin granules is coupled to the electrical component of the H+ electrochemical gradient and raises the possibility that chemiosmotic mechanisms of the granules may be involved in catecholamine secretion from chromaffin cells. The study also demonstrates that chemiosmotic processes of chromaffin granules can affect the uptake of drugs into the storage vesicles.
Examining the Effectiveness of Celebrity Advertising to Minorities: Entertainers vs. Athletes

Advertising testimonials are almost as old as advertising itself. Dating back at least to the time the first merchant added "by appointment to his Majesty" to his flyers, testimonial claims have been a favorite form of advertising (Starch 1984). Today testimonials through the use of product endorsers are still widely used. Much of this usage focuses on the celebrity endorser. For instance, estimates are that from one-third to three-fifths of prime-time television commercials use celebrity endorsements, while celebrity usage accounts for ten percent of all commercials (Forkan 1980).
Unintentional subdural block during labor epidural in a parturient with prior Harrington rod insertion for scoliosis. Case report.

Background and Objectives The authors report a case of unintentional subdural block in a parturient with prior Harrington rod insertion. Methods The epidural technique was performed successfully at the L5-S1 interspace using the loss-of-resistance technique after two failed attempts at the L3-4 interspace. Results Twenty to 30 minutes after total initial dose of 9 mL 0.25% bupivacaine with 1/200,000 epinephrine, the patient developed hypotension and a high sensory block involving the trigeminal nerve. The patient also complained of difficulties in swallowing and breathing. Signs and symptoms strongly suggested an unintentional subdural block. After careful monitoring and reassurance, the patient’s sensory level receded and she could breathe and swallow comfortably. Intubation was not required. The epidural catheter was maintained in the same space. The amount of 0.25% bupivacaine was reduced to 2 mL for subsequent top-ups. Adequate analgesia was provided throughout the course of her labor and delivery without other complications. Conclusions Lumbar epidural anesthesia is not always an easily performed technique and is known to be associated with a higher incidence of complications in patients with prior Harrington rod insertion. Prompt recognition and proper management of subdurally placed needle and catheter avoided more serious complications.
Urinary and plasma oxytocin changes in response to MDMA or intranasal oxytocin administration.

Abstract Background The neuropeptide oxytocin (OT) has received increased experimental attention for its putative role in both normal social functioning and several psychiatric disorders that are partially characterized by social dysfunction (e.g., autism spectrum disorders: ASD). Many human experimental studies measure circulating plasma levels of OT in order to examine the relationship between the hormone and behavior. Urinary OT (uOT) assays offer a simple, easy, and non-invasive method to measure peripheral hormone levels, but the correspondence between uOT and plasma OT (pOT) levels is unclear. Here, we conducted two within-subjects, double-blind studies exploring changes in uOT and pOT levels following administration of two drugs: MDMA, an oxytocin-releasing drug (Study 1), and intranasal oxytocin (INOT: Study 1 and 2). Methods In Study 1, 14 adult participants (2 females) were each administered either oral 1.5 mg/kg MDMA or 40 IU INOT across two different study sessions. In Study 2, 10 male participants (adolescents and young adults) diagnosed with ASD received either 40 IU INOT or placebo across two different sessions. In both studies, blood and urine samples were collected before and after drug administration at each study session. For Study 1, 10 participants provided valid plasma and urine samples for the MDMA session, and 8 provided valid samples for the INOT session. For Study 2, all 10 participants provided valid samples for both INOT and placebo sessions. Pre- and post-administration levels of pOT and uOT were compared. Additionally, correlations between percent change from baseline uOT and pOT levels were examined. Results Study 1: Plasma OT and uOT levels significantly increased after administration of MDMA and INOT. Furthermore, uOT levels were positively correlated with pOT levels following administration of MDMA (r = 0.57, p = 0.042) but not INOT (r = 0.51, p=0.097). Study 2: There was a significant increase in uOT levels after administration of INOT, but not after administration of placebo. Under both conditions, INOT and placebo, significant increases in pOT levels were not observed. Additionally, change from baseline uOT and pOT levels were positively correlated (r = 0.57, p=0.021). There was no significant correlation between uOT and pOT levels following placebo administration. Conclusion Our results show a measurable and significant increase in pOT and uOT levels after the administration of MDMA (Study 1) and INOT (Study 1 and Study 2). Additionally, a positive correlation between uOT and pOT levels was observed in both samples (healthy adults and ASD patients) in at least one condition. However, uOT and pOT levels were not correlated under all conditions, suggesting that uOT levels do not fully correspond to pOT levels in the time windows we measured. Future studies should further examine the relationship between levels of pOT and uOT in healthy and clinical populations on measures of social behavior because uOT may serve as an additional non-invasive method to measure peripheral OT changes.
Low-Dose Aspirin and Pancreatic Cancer Risk—Reply

I thank Drs. Brasky and Wactawski-Wende for their positive and constructive observations about our observed reduced risk of pancreatic cancer with aspirin use ([1][1]). The risk relationship is interesting, especially as a number of plausible mechanisms for aspirin involvement in risk have been
Diagnosis and Treatment of Acute Diarrhea

A patient has diarrhea if unformed bowel movements occur at a daily rate twice that of the usual rate. Diarrhea of infectious origin generally is associated with one or more symptoms of intestinal infection: fever, nausea, vomiting, abdominal pain or cramps, or dysentery (bloody and mucoid stools). The number of persons exposed to enteropathogens who develop illness depends upon the inoculum size. Host factors and virulence properties of the organism affect the clinical response.
Incidence, Distribution, and Pathogenicity of Fungi Causing Root Rot in Idaho Long-Term Sugar Beet Storage Piles

Fungal rots in sugar beet roots held in long-term storage can lead to considerable sucrose loss but the incidence and distribution of fungal rots inside sugar beet piles and pathogenicity for some ...
‘I just Love Research’: Beliefs about What Makes Researchers Successful

There is a longstanding belief that research should be a calling more than a job. How does this expectation shape the selection of future researchers? Specifically, undergraduate research experienc...
A location and mobility independent scheme to quantify the neighbourhood stability of a node in mobile sensor networks

We propose to quantify the neighbourhood stability of a node without using the location and mobility information of the nodes in a mobile sensor network (MSN). We make use of the notion of Jaccard similarity to quantify the similarity in the sets of neighbours of a node between any two successive sampling time instants and compute the weighted average of the Jaccard neighbourhood similarity (WJNS) over a period of time. Our hypothesis is that nodes with larger WJNS scores have a stable neighbourhood and could be preferred for inclusion as intermediate nodes for stable paths. We validate our hypothesis through extensive simulations: The lifetime of the WJNS-based paths is significantly larger than that of the minimum hop paths and the predicted link expiration time (LET)-based paths; the trade-off being a marginal increase in the hop count compared to that of the minimum hop paths.
Computer Modeling of the Evolution of Dendrite Microstructure in Binary Alloys During Non-isothermal Solidification

Two-dimensional simulations of the evolution of dendrite microstructure during isothermal and non-isothermal solidifications of a Ni-0.41Cu binary alloy are carried out using the phase-field method. The governing evolution equation for the phase field variable, the solute mole fraction and the temperature are formulated and numerically solved using an explicit finite difference scheme. To make the computations tractable, parallel computing is employed. The results obtained show that under lower cooling rates, the solidification process is controlled by partitioning of the solute between the solid and the liquid at the solid/liquid interface. At high cooling rates, on the other hand, solute trapping takes place and solidification is controlled by the heat extraction rate. An increase in the cooling rate is also found to have a pronounced effect on the dendrite microstructure causing it to change from poorly developed dendrites consisting of only primary stalks, via fully developed dendrites containing secondary and tertiary arms to the diamond-shaped grains with cellular surfaces. These findings are in excellent agreement with experimental observations.
Experienced individuals influence the thermoregulatory fanning behaviour in honey bee colonies

The survival of an animal society depends on how individual interactions influence group coordination. Interactions within a group determine coordinated responses to environmental changes. Individuals that are especially influential affect the behavioural responses of other group members. This is exemplified by honey bee worker responses to increasing ambient temperatures by fanning their wings to circulate air through the hive. Groups of workers are more likely to fan than isolated workers, suggesting a coordinated group response. But are some individuals more influential than others in this response? This study tests the hypothesis that an individual influences other group members to perform thermoregulatory fanning behaviour in the western honey bee, Apis mellifera L. We show that groups of young nurse bees placed with fanners are more likely to initiate fanning compared to groups of nurses without fanners. Furthermore, we find that groups with young nurse bees have lower response thresholds than groups of just fanners. Our results suggest that individuals have the capability to influence other individuals to follow their fanning response as temperatures increase, and these social dynamics balance probability of fanning with thermal response thresholds. An influential individual may ultimately affect the ability for a society to efficiently respond to environmental fluctuations.
The Relationship of Early Maladaptive Schemas and Anticipated Risky Behaviors in College Students

The developmental transition from adolescence to adulthood, a period of time known as emerging adulthood, is marked by great personal growth and interpersonal maturation (Arnett, Emerging adulthood: The winding road from the late teens through the twenties, Oxford University Press, New York, 2004). Risk-taking behaviors are seen as a significant impediment to positive development during emerging adulthood. However, few researchers have examined how underlying cognitive processes contribute to the development and exacerbation of risk-taking behaviors at this time. In the current study, we examined the multivariate associations between early maladaptive schemas (disconnection and rejection, impaired autonomy, impaired limits, other-directedness, overvigilance, and inhibition) and expected involvement in five indices of risky behaviors for college women (n = 341) and college men (n = 143). Gender-specific patterns emerged in the prediction of different risk-behavior indices. Early maladaptive schemas accounted for 24% of the variance in men’s anticipated engagement in risky sexual behavior (vs. 9% of women’s). Early maladaptive schemas accounted for 20% of the variance in women’s anticipated engagement in both academic/work and illegal/aggressive risky behaviors (vs. 11 and 9% of men’s). In addition, unique schema domains differentially predicted variance in risky sexual, illicit drug use, heavy drinking, and aggressive/illegal risk behavior for each gender. Gender-sensitive and schema-specific prevention efforts for different types of risky behaviors, often present during emerging adulthood, may be warranted.
A SVD Based Pattern Matching Approach for Color Image Retrieval

To make the pattern matching more accurate, local pattern matching algorithms could be applied upon suitably decomposed images. In this paper, SVD (Singular Value Decomposition) technique followed by LBP (Local Binary Pattern) algorithm has been applied to the images in RGB color space. Feature vectors are obtained for individual component of RGB and then merged to get the final feature vector. CBIR performed upon these feature vectors yielded better results and values of precision, recall and f-score was found to be 56.08, 84.13 and 67.3 respectively for the technique LBP-S-RGB with an optimal bin-size of 256.
HearU: An Integrated System to Raise Awareness of Hearing Loss

Hearing loss is a prevalent public health crisis that often goes unnoticed in public eye due to its invisibility. People who are hard of hearing (HH) often experience social isolation caused by the lack of understanding from the hearing community. Our research revealed that there is a communication gap between the hearing and HH communities. The current state of art tends to focus on assisting HH people to participate in conversations, which places more responsibility on the HH community. There is a lack of responsibility of people in the hearing community. However, communication works in two directions; it requires both parties to take responsibility. In this paper, we present HearU - an integrated, multichannel system that includes public interaction. Through the creation of an immersive experience that increases people's awareness of hearing loss, we aim to use HearU as a medium to weave these two communities together as a whole.
Expanding Access to Education Through Open Educational Resources (OERs)

This chapter provides an overview of efforts to reduce the cost of textbooks for students at Hostos Community College through various Open Educational Resource (OER) initiatives and describes how these efforts are supported college-wide. It begins with a brief definition of Open Access and an overview of current research showing how the high cost of commercially produced textbooks creates barriers to academic success for community college students. It then describes several initiatives at Hostos, designed to replace commercial, high-cost textbooks with open textbooks and other Open Educational Resources—including developing an entire Early-Childhood Education Associate’s degree program using only open resources as required texts. The chapter goes on to discuss the challenges and benefits of creating and adopting open resources for courses—from revisiting learning outcomes to building institutional support for this sometimes difficult work. Faculty who have adopted open resources and the librarians and educational technologists who support them have developed a dedicated community, and the values of access and equity which are central to the college’s mission are well-served by these initiatives.
Cationic cell-penetrating peptide is bactericidal against Neisseria gonorrhoeae.

Objectives Cell-penetrating peptides (CPPs) have been evaluated for intracellular delivery of molecules and several CPPs have bactericidal activity. Our objectives were to determine the effect of a 12 amino acid CPPs on survival and on the invasive and inflammatory potential of Neisseria gonorrhoeae. Methods Survival of MDR and human challenge strains of N. gonorrhoeae grown in cell culture medium with 10% FBS was determined after treatment with the CPP and human antimicrobial peptide LL-37 for 4 h. Confocal microscopy was used to examine penetration of FITC-labelled CPP into bacterial cells. The ability of the CPP to prevent invasion of human ME-180 cervical epithelial cells and to reduce the induction of TNF-α in human THP-1 monocytic cells in response to gonococcal infection was assessed. Cytotoxicity of the CPP towards the THP-1 cells was determined. Results The CPP was bactericidal, with 95%-100% killing of all gonococcal strains at 100 μM. Confocal microscopy of gonococci incubated with FITC-labelled CPP revealed the penetration of the peptide. CPP treatment of N. gonorrhoeae inhibited gonococcal invasion of ME-180 cells and reduced the expression of TNF-α induced in THP-1 cells by gonococci. The CPP showed no cytotoxicity towards human THP-1 cells. Conclusions Based on these promising results, future studies will focus on testing of CPP in the presence of other types of host cells and exploration of structural modifications of the CPP that could decrease its susceptibility to proteolysis and increase its potency.
Towards utilizing internet of things (IoT) devices for understanding individual occupants' energy usage of personal and shared appliances in office buildings

Author(s): Rafsanjani, Hamed Nabizadeh; Ghahramani, Ali | Abstract: Energy consumption in office buildings highly depends on occupant energy-use behaviors and intervening these behaviors could function as a cost-effective approach to enhance energy savings. Current behavior-intervention techniques extensively rely on occupant-specific energy-use information at the workstation level and often ignore shared appliances. It is because an occupant typically has full responsibility for her workstation appliances energy consumption and shares the responsibility of the shared appliances energy consumption. However, understanding energy-use behavior of both workstation and shared appliances is necessary for applying appropriate behavior-intervention techniques. Despite this importance, there is still no practical and scalable method to capture personalized energy-use information of workstation and shared appliances since the conventional methods use plug-in power meters that are extremely expensive and difficult to maintain over long period of time. To address this gap, we propose a comprehensive occupant-level energy-usage approach which utilizes the data from the internet of things devices in office buildings to provide information related to energy-use behavior of workstation and shared appliances of each occupant in an economical and feasible manner. In particular, we introduce an energy behavior index which quantitatively compares individual occupants’ energy-consuming data to identify high energy consumers and inefficient behaviors. Results from an experiment conducted in an office building equipped with internet of things devices demonstrate the feasibility of the proposed approach to classify occupants to different energy-usage categories. Our proposed approach along with appropriate behavior-intervention techniques could be used to impact occupant energy-use behaviors.
Shakespeare’s Plays of Deranged Authority: The King’s Three Bodies

Shakespeare’s plays are situated upon the threshold of two worlds: a declining traditional order torn apart by political rivalry and ascendant early-modern capitalism. The history plays dramatize infighting among warring factions of privileged aristocrats as well as revolutionary forces propelled by the rising commons and the politics of commodity. Legitimate authority is rarely secure among the kings perched upon Shakespearean thrones. In Shakespeare’s Henriad and King John , crowns are contested from the moment they are placed upon royal heads, inspiring Kantorwicz’s political theology: the corporeal body of short-lived kings is distinct from the sovereign’s sublime body that reigns without cease. “The King is dead, long live the King!” A re-reading of Shakespeare’s plays of deranged authority reveals, as Lacan would predict, that his kings possess three bodies: corpo-“real,” imaginary, and symbolic. When fractured and animated by different characters, the king’s three bodies map onto Weber’s three modes of legitimate domination. In King John , the “imaginary” body of the king – the character most capable of acting with noble warrior honor expected of Kings – is the charismatic “Bastard” who can never ascend to symbolic legitimacy. The article ends with an analysis of the three bodies of sovereignty in the contemporary moment of deranged authority: Trumpism.
[Oxybis(ethane-1,2-di­yl)]bis­(di­methyl­ammonium) octa­molybdate dihydrate

The title compound, (C8H22N2O)2[Mo8O26]·H2O, (cis-H2L)2[β-Mo8O26]·H2O, where L = (bis­[2-N,N-di­methyl­amino)­eth­yl] ether), was synthesized from bis­[2-(di­methyl­amino)­eth­yl] ether and MoO3 under solvothermal conditions and characterized by multinuclear NMR and single-crystal X-ray diffraction techniques. The structure displays two [oxybis(ethane-1,2-di­yl)]bis­(di­methyl­ammonium), or [cis-H2L]2+, cations, a central [β-Mo8O26]4− anionic cluster consisting of eight distorted MoO6 octa­hedra, and two water mol­ecules in their deuterated form. The central anion lies across an inversion center. The [cis-H2L]2+ cations are hydrogen bonded to the central [β-Mo8O26]4− cluster via bridging water mol­ecules. In the crystal, O—H⋯O hydrogen bonds link the components into chains along [010]. Weak C—H⋯O hydrogen bonds link these chains into a three-dimensional network.
Effects of corn vs corn gluten feed on site, extent and ruminal rate of forage digestion and on rate and efficiency of gain.

Three digestion experiments and one growth experiment were conducted to determine site, extent and ruminal rate of forage digestion and rate and efficiency of gain by cattle offered alfalfa haylage supplemented with corn or dry corn gluten feed (CGF). In Exp. 1, eight steers were fed alfalfa haylage-based diets with substitution of corn for 0, 20, 40 or 60% of haylage in a 4 X 4 latin square. Increasing dietary corn substitution increased (P less than .05) OM, NDF and ADF digestion by steers but decreased (P less than .05) rate of in situ alfalfa DM digestion. In Exp. 2, five heifers were fed alfalfa haylage-based diets with increasing dietary levels of CGF in a 5 X 5 latin square. Increasing dietary CGF increased (P less than .05) OM, NDF and ADF digestion by heifers. In Exp. 3 and 4, cattle were fed alfalfa haylage-based diets containing either 20 or 60% corn or CGF. In Exp. 3, supplementation increased (P less than .05) OM and NDF digestion but level X supplement source interaction (P less than .05) occurred, with added CGF increasing OM and NDF digestion more than added corn. In Exp. 4, supplementation improved (P less than .05) DM intake, daily gain and feed efficiency. Dry matter intake and daily gain were greater (P less than .05) for 60% supplementation than for 20% supplementation. Overall, whereas increasing the level of dietary supplement increased (P less than .05) OM, NDF and ADF digestion, only corn addition decreased (P less than .05) rate of in situ alfalfa DM digestion. Daily gains and feed efficiencies were similar in cattle fed either corn or CGF with alfalfa haylage.
Patterns and predictors of recurrent acute care use among Medicaid beneficiaries with systemic lupus erythematosus

Abstract Objectives We aimed to identify longitudinal patterns and predictors of acute care use (emergency department [ED] visits and hospitalizations) among individuals with SLE enrolled in Medicaid, the largest U.S. public insurance. Methods Using Medicaid data (29 states, 2000–2010) we identified 18–65-year-olds with SLE (≥3 SLE ICD-9 codes, 3rd code=index date), ≥12 months of enrollment prior to the index date and ≥24 months post. For each 90-day interval post index date, patients were assigned binary indicators (1=≥1 ED visit or hospitalization, 0=none). We used group-based trajectory models to graph patterns of overall and SLE-specific acute care use, and multinomial logistic regression models to examine predictors. Results Among 40,381 SLE patients, the mean age was 40.8 (SD 11.9). Using a three-group trajectory model, 2,342 (6%) were recurrent all-cause high acute care utilizers, 12,932 (32%) moderate, 25,107 (62%) infrequent; 25% were moderate or high utilizers for SLE. There were higher odds of all-cause, recurrent acute care use (vs. infrequent) among patients with severe vs. mild SLE (OR 3.37, 95% CI 3.0–3.78), chronic pain (odds ratio [OR] 1.63, 95% CI 1.15–2.32), depression (OR 1.90 95% CI 1.74–2.09), and cardiovascular disease (OR 2.29, 95% CI 2.08–2.52). Older age, male sex and hydroxychloroquine use were associated with lower odds of recurrent overall and SLE-specific acute care use. Conclusion Nearly 40% of Medicaid beneficiaries with SLE are recurrent all-cause acute care utilizers; 25% have recurrent use for SLE. Modifiable factors, including outpatient management of SLE and comorbidities, may reduce avoidable acute care use.
Mesoporous microspherical NiO catalysts for the deoxygenation of oleic acid

Abstract Mesoporous NiO catalysts were synthesized via surfactant assisted self-assembly employing structure directing agents CTAB and P123. The resultant catalysts had similar chemical composition but different physical properties including mesoporous ordering, surface area, and pore size. The mesoporous oxides were used as catalysts in the deoxygenation of oleic acid to heptadecane. The catalysts synthesized with P123 displayed the highest yields to heptadecane (63%) tripling the performance of commercial NiO (19%). A phase change from NiO to Ni was observed during the deoxygenation reaction. The recyclability of the catalyst synthesized with P123 was evaluated.
The number of saddles of the spherical $p$-spin model

We show that the quenched complexity of saddles of the spherical pure $p$-spin model agrees with the annealed complexity when both are positive. Precisely, we show that the second moment of the number of critical values of a given finite index in a given interval has twice the growth rate of the first moment.
International Virtual Collaboration in Advertising Courses: Building International and Intercultural Skills from Home.

This article describes how an international education component for an Advertising and Society course was developed and taught for undergraduate students through a virtual collaboration between Ame...
Factors associated with sleep disturbances in women undergoing treatment for early-stage breast cancer.

The purpose of this study was to examine factors associated with sleep disturbance in women receiving adjuvant therapy for breast cancer. This study employed a cross-sectional design using data collected at 3 months post-surgery from an ongoing longitudinal parent study. Participant data were divided into adjuvant treatment groups (chemotherapy, radiation, and aromatase inhibitors) and no adjuvant treatment groups. Symptoms were measured using patient self-report measures. Analysis of variance was used to assess between adjuvant treatment group differences in sleep disturbance. Regression analysis was performed to assess the relationship between sleep disturbance and other symptoms within adjuvant treatment groups. The sample included 156 women diagnosed with early-stage breast cancer. There were significant differences in levels of reported sleep disturbance between treatment groups (p = 0.049), with significantly higher levels of sleep disturbances in those receiving radiation compared to those receiving no adjuvant treatment (p = 0.038) and in those receiving chemotherapy and those receiving no adjuvant treatment (p = 0.027). Increased sleep disturbance was found to be a significant predictor for increased pain severity, nausea severity, anxiety, depressive symptoms, fatigue, decreased physical function, and decreased ability to participate in social roles and activities. Co-occurring symptoms with sleep disturbance differed between adjuvant treatment groups. Sleep disturbance was also associated with younger age (p = 0.008). Patients undergoing chemotherapy or radiation for breast cancer report higher levels of sleep disturbance than those not receiving adjuvant therapy. Sleep disturbance is associated with other symptoms experienced by patients with cancer and thus requires continual assessment and future research into effective interventions.
Minority stress process among older Black Americans: the role of age, perceived discrimination, and anxiety

Objective: Prolonged experiences of discrimination can be a major source of physical and health-related stress, particularly in older Black Americans. However, there is limited information on the r...
Push and pushback: Control behavior as a precipitant of verbal and violent disputes

We examine to what extent control behavior precipitates disputes involving adversaries in different social relationships. We hypothesize that disputes between intimate partners and illegal business partners are more likely than other disputes to involve control because they involve a higher level of interdependence between the participants. A sample of male inmates (n = 479) and nonoffenders (n = 206) were asked whether control behaviors (e.g., verbal commands) precipitated their most recent disputes (n = 1184). Bivariate probit regression models allowed us to examine mutual control as well as unilateral control. Disputes between intimate partners were more likely than disputes between adversaries in other relationships to be precipitated by mutual control, but not unilateral or one-sided control by men. Disputes between illegal business partners also predicted mutual control, but not unilateral control. Discussions of the motives for violence would benefit from consideration of the classic social psychological literature on power and influence.
Harm Reduction: Pragmatic Strategies for Managing High-Risk Behaviors

Part I: Overview of Harm Reduction. Collins, Clifasefi, Logan, Samples, Somers, Marlatt, Current Status, Historical Highlights, and Basic Principles of Harm Reduction. Tatarsky, Kellogg, Harm Reduction Psychotherapy. Part II: Areas of Concentration in Harm Reduction. Larimer, Dillworth, Neighbors, Lewis, Montoya, Logan, Harm Reduction for Alcohol Problems. Phillips, Heavner, Bergen, Nissen, Tobacco: Untapped Potential for Harm Reduction. Roffman, Stephens, Harm Reduction and Cannabis. Kilmer, Cronce, Hunt, Lee, Reducing Harm Associated with Illicit Drug Use: Opiates, Amphetamines, Cocaine, Steroids, and Other Substances. Andrasik, Lostutter, Harm Reduction for High-risk Sexual Behavior and HIV. Denning, Redefining the Treatment of Dual Disorders. Part III: Harm Reduction and Special Populations. Andrasik, Woods, George, The Need for Culturally Competent Harm Reduction and Relapse Prevention Interventions for African Americans. Blume, Resor, Harm Reduction Among Hispanic and Latino Populations. Osilla, Wong, Zane, Harm Reduction for Asian American and Pacific Islander Populations. Kelly, Adolescent Alcohol-related Harm Reduction: Realities, Innovations, and Challenges. Part IV: The Role of Harm Reduction in U.S. Drug Control Policy. Walthers, Weingardt, Witkiewitz, Marlatt, Harm Reduction and Public Policy.
Scalable Regulation of Inter-enterprise Electronic Commerce

In the current electronic-commerce literature, a commercial transaction is commonly viewed as an exchange between two autonomous principals operating under some kind of contract between them--which needs to be formalized and enforced. But the situation can be considerably more complex in the case of inter-enterprise (also called business-to-business, or B2B) commerce. The participants in a B2B transaction are generally not autonomous agents, since their commercial activities are subject to the policies of their respective enterprises.It is our thesis, therefore, that a B2B transaction should be viewed as being governed by three distinct policies: the two policies that regulate the activities of the two principals, while operating as representatives of their respective enterprises, and the policy that reflects the contract between the two enterprises. These policies are likely to be independently developed, and may be quite heterogeneous. Yet, they have to interoperate, and must all be brought to bear in regulating each B2B transaction. This paper presents a mechanism for formulating such interoperating policies, and for their scalable enforcement, thus providing for regulated inter-enterprise electronic commerce.
Does birth under-registration reduce childhood immunization? Evidence from the Dominican Republic.

The consequences of lacking birth certificates remain largely unexplored in the economic literature. We intend to fill this knowledge gap studying the effect of lacking birth certificates on immunization of children in the Dominican Republic. This is an interesting country because a significant number of children of Haitian descent face the consequences of lacking proper documentation. We use the distance to the civil registry office and the mother’s document of identification as instrumental variables of the child’s birth certificate. After controlling for distance to immunization services and other determinants, this paper finds that children between 0 and 59 months of age that do not have birth certificates are behind by nearly one vaccine (out of a total of nine) compared to those that have birth certificates.