cssi/SciSciGPT-SciSciNet huggingface dataset:
Climate change vulnerability assessment in Georgia

Climate change is occurring in the Southeastern United States, and one manifestation is changes in frequency and intensity of extreme events. A vulnerability assessment is performed in the state of Georgia (United States) at the county level from 1975 to 2012 in decadal increments. Climate change vulnerability is typically measured as a function of exposure to physical phenomena (e.g., droughts, floods), sensitivity to factors affecting the social milieu, and the capacity of a given unit to adapt to changing physical conditions. The paper builds on previous assessments and offers a unique approach to vulnerability analyses by combining climatic, social, land cover, and hydrological components together into a unified vulnerability assessment, which captures both long-term and hydroclimatic events. Climate change vulnerability indices are derived for the 1980s, 1990s, 2000s, and 2010s. Climate change exposure is measured as: 1) departure of decadal mean temperature and precipitation from baseline temperature and precipitation (1971e2000) using the United States Historical Climatology Network version 2.5 and 2) extreme hydroclimatic hazards indicated by flood, heat wave and drought events. Sensitivity and adaptive capacity are measured by well-established conceptualizations and methods built derived from socioeconomic variables. Impervious surface and flood susceptibility area are also incor- porated to account for place-based vulnerability. Anomalies in temperature and precipitation with an overall trend towards drying and warming have been observed. The anomalous cooling period in Georgia during the 1970e1980 period as well as the post-1980 warm-up have been captured with a clearly established increase in extreme hydroclimatic events in recent decades. Climate vulnerability is highest in some metropolitan Atlanta and coastal counties. However, the southwestern region of Georgia, and part of the rural Black belt region are found to be especially vulnerable to climate change.
Polymerization of alkoxyallenes by transition‐metal catalysts

The structure of polymers obtained by polymerization of methoxyallene and ethoxyallene with transition-metal catalysts depends on the catalyst employed. Rapid polymerization at 0°C through the unsubstituted double bond occurred with π-allylnickel halides, NiCl2/AlEt3 and CoCl2/AlEt3, yielding polymers with the structure Typical Ziegler–Natta catalysts (TiCl4, VOCl3 or FeCl3 with AIEt3) gave polymers mainly with the structure although some of the structural units were probably present as well. Polymers having conjugated double bonds were prepared with PdCl2, [(π-allyl)PdCl]2, and PdCl2(C6H5CN)2 as catalysts. Palladium iodide produced polymers with all three of the above structural units present. Polymerization occurred more slowly with these palladium catalysts. A preliminary examination of the effect of variation of solvent, ligand, co-catalyst, and temperature on the rate and structure of the polymers obtained with the palladium catalysts is reported.
Context-aware computing support for the educationally disadvantaged

The educationally disadvantaged people in context-aware computing are those without any programming experience, and are unable to build context-aware applications with the current level of available prototyping support. iCAP is a system that assists this group of non-programmers in visually designing context-aware applications without writing any code. Individuals are then able to rapidly prototype their application in a simulated or real context-aware environment. Through iCAP, programming context-aware computing is made intuitive and viable for the educationally disadvantaged.
Beyond bad behaving brothers: productive performances of masculinities among college fraternity men

Research on fraternity men focuses almost exclusively on problematic behaviors such as homophobia and sexism, alcohol abuse, violence against women, sexual promiscuity, and the overrepresentation of members among campus judicial offenders. Consequently, little is known about those who perform masculinities in healthy and productive ways. Presented in this article are findings from a qualitative study of productive masculinities and behaviors among 50 undergraduate fraternity men from 44 chapters across the US and Canada. Findings offer insights into participants’ steadfast commitments to the fraternity’s espoused values; their acceptance and appreciation of members from a range of diverse backgrounds; strategies they employed to address bad behaviors (including sexism, racism, and homophobia) among chapter brothers; and the conditions that enabled them to behave in ways that contradict stereotypes concerning men in collegiate fraternities.
Automated gesture segmentation from dance sequences

Complex human motion (e.g. dance) sequences are typically analyzed by segmenting them into shorter motion sequences, called gestures. However, this segmentation process is subjective, and varies considerably from one choreographer to another. Dance sequences also exhibit a large vocabulary of gestures. In this paper, we propose an algorithm called hierarchical activity segmentation. This algorithm employs a dynamic hierarchical layered structure to represent human anatomy, and uses low-level motion parameters to characterize motion in the various layers of this hierarchy, which correspond to different segments of the human body. This characterization is used with a naive Bayesian classifier to derive choreographer profiles from empirical data that are used to predict how particular choreographers segment gestures in other motion sequences. When the predictions were tested with a library of 45 3D motion capture sequences (with 185 distinct gestures) created by 5 different choreographers, they were found to be 93.3% accurate.
The danger of epigenetics misconceptions (epigenetics and stuff

Within the past two decades, the fields of chromatin structure and function and transcription regulation research started to fuse and overlap, as evidence mounted to support a very strong regulatory role in gene expression that was associated with histone post-translational modifications, DNA methylation, as well as various chromatin-associated proteins (the pillars of the "Epigenetics" building). The fusion and convergence of these complementary fields is now often simply referred to as "Epigenetics". During these same 20 years, numerous new research groups have started to recognize the importance of chromatin composition, conformation, and its plasticity. However, as the field started to grow exponentially, its growth came with the spreading of several important misconceptions, which have unfortunately led to improper or hasty conclusions. The goal of this short "opinion" piece is to attempt to minimize future misinterpretations of experimental results and ensure that the right sets of experiment are used to reach the proper conclusion, at least as far as epigenetic mechanisms are concerned.
Leveraging Higher Order Dependencies between Features for Text Classification

Traditional machine learning methods only consider relationships between feature values within individual data instances while disregarding the dependencies that link features across instances. In this work, we develop a general approach to supervised learning by leveraging higher-order dependencies between features. We introduce a novel Bayesian framework for classification named Higher Order Naive Bayes (HONB). Unlike approaches that assume data instances are independent, HONB leverages co-occurrence relations between feature values across different instances. Additionally, we generalize our framework by developing a novel data-driven space transformation that allows any classifier operating in vector spaces to take advantage of these higher-order co-occurrence relations. Results obtained on several benchmark text corpora demonstrate that higher-order approaches achieve significant improvements in classification accuracy over the baseline (first-order) methods.
Bacteriological Study of Platelet Concentrates Stored at 22 C and 4 C

Samples of platelet concentrate prepared by double plasmapheresis of volunteers were stored at 4 C and 22 C for four to ten days and cultured from 0072 hours on brain heart infusion media, thioglycolate broth, and tryptic soy broth and incubated at 22 and 37 C for 21 days. A closed system was used for 42 units and a limited entry system involving pooling of platelet concentrates was used for 68 units. All 110 units were negative for bacterial contamination at both 4 C and room temperature, based on cultures using multiple media under maximized growth conditions for anaerobic as well as aerobic bacteria. Platelet concentrates handled in both a closed system and a limited entry system and stored up to at least 72 hours at room temperature remained free of bacterial contamination and appeared safe for transfusion.
Erythrocyte Omega-6 and Omega-3 Fatty Acids and Mammographic Breast Density

Diets low in omega-6 (n-6) polyunsaturated fatty acids (PUFAs) and high in omega-3 (n-3) PUFAs may protect against breast cancer development. Associations of PUFA intake with mammographic density, an intermediate marker of breast cancer risk, have been inconsistent; however, prior studies have relied on self-reported dietary PUFA intake. We examined the association between circulating erythrocyte n-6 and n-3 PUFAs with mammographic density in 248 postmenopausal women who were not taking exogenous hormones. PUFAs in erythrocytes were measured by gas-liquid chromatography, and mammographic density was assessed quantitatively by planimetry. Spearman's correlation coefficients and generalized linear models were used to evaluate the relationships between PUFA measures and mammographic density. None of the erythrocyte n-6 or n-3 PUFA measures were associated with percent density or dense breast area.
The Transport of Radioactive Inorganic Phosphate by the Pulmonary Circulation

Radio-phosphorus in the form H3P32O4, injected in aqueous solution, is found to give flow-dilution curves and values for cardiac output indistinguishable from those obtained with T-1824 in normal anesthetized dogs. The fairly rapid disappearance of the P32 from systemic blood is a technical advantage if the measurement of output is to be repeated at short intervals.
750 GeV diphotons from a D3-brane

Motivated by the recently reported diphoton excess at 750 GeV observed by both CMS and ATLAS, we study string-based particle physics models which can accommodate this signal. Quite remarkably, although Grand Unied Theories in F-theory tend to impose tight
Impact of Nanotechnology on Therapeutic Angiogenesis

Controlled and stipulated induction of angiogenesis, commonly known as therapeutic angiogenesis, can be used as a treatment strategy for many ischemic diseases and tissue regenerations. The current and conventional method of therapeutic angiogensis, which takes advantage of this natural phenomenon by inducing neovascularization in a specific body organ or site, has many disadvantages including side effects and higher dose requirements. The emergence of nanotechnology, particularly its use as a multifunctional and surface-tunable nanocarrier with site specificity and the ability to incorporate and protect active materials from in vivoenvironmental assault, has the potential for a sea change in the therapeutic angiogenesis area of research. This chapter gives a brief description of some of the nanotechnology-based therapeutic angiogenesis strategies used in recent years. Though most of the strategies, which involve delivering growth factors and therapeutic genetic materials, are in a preclinical state, there are great potential clinical implications for the near future.
Parametric Bilinear Generalized Approximate Message Passing

We propose a scheme to estimate the parameters $b_i$ and $c_j$ of the bilinear form $z_m=\sum_{i,j} b_i z_m^{(i,j) } c_j$ from noisy measurements $\{y_m\}_{m=1}^M$ , where $y_m$ and $z_m$ are related through an arbitrary likelihood function and $z_m^{(i,j) }$ are known. Our scheme is based on generalized approximate message passing (G-AMP): it treats $b_i$ and $c_j$ as random variables and $z_m^{(i,j) }$ as an i.i.d. Gaussian 3-way tensor in order to derive a tractable simplification of the sum-product algorithm in the large-system limit. It generalizes previous instances of bilinear G-AMP, such as those that estimate matrices ${B}$ and ${C}$ from a noisy measurement of ${Z}={BC}$ , allowing the application of AMP methods to problems such as self-calibration, blind deconvolution, and matrix compressive sensing. Numerical experiments confirm the accuracy and computational efficiency of the proposed approach.
Estimating preseason irrigation losses by characterizing evaporation of effective precipitation under bare soil conditions using large weighing lysimeters

Abstract Irrigation from the Ogallala aquifer is used to supplement insufficient precipitation for agricultural crop production in the semi-arid Texas High Plains. Decreased pumping capacity has compelled many producers to “pre-water” fields to field capacity prior to planting to hedge against pumping limitations later in the season. However, the direct measurement of evaporative losses from preseason irrigation of bare soil is not commonly studied. The quantification of evaporative losses from effective precipitation, or the net amount of water that infiltrates into the soil following a precipitation event, can be used as a surrogate for estimating losses from preseason irrigation. We identified 35 precipitation events that occurred over lysimeter fields under fallow conditions in 2002, 2005, and 2009. Events were categorized into four bins of precipitation magnitude ranging from 3 mm to 35 mm. Subsequent evaporation was measured for a period of up to seven days following rainfall events using large weighing lysimeters at the USDA-ARS Conservation and Production Research Laboratory in Bushland, TX. An exponential decay function was used to characterize bare soil evaporation using maximum cumulative measured evaporation ( E Cmax ), soil water transfer constant ( k ), and cumulative grass reference evapotranspiration (ET Cos ). The wide range of E Cmax values and k values demonstrated the sensitivity of evaporative losses to both antecedent soil water content and evaporative demand. We also present measured average daily evaporation values for a range of evaporative demand regimes for each precipitation bin. From data analyzed in this study, nearly all of the water from precipitation events of 10 mm and less were lost to evaporation within the following day under moderate to high grass reference evapotranspiration (ET os ) conditions. Nearly all water from precipitation events between 20 and 30 mm was lost to evaporation between three to four days following the event under similar evaporative demand. The considerable potential evaporative losses from preseason irrigation call into the question the prudence of the preseason irrigation, particularly for regions with limited groundwater resources.
A multipoint viscous design method for multi-element airfoils

A multipoint viscous inverse method has been developed for the design of multi-element airfoils in incompressible flow. The method allows the designer to prescribe either inviscid velocity distributions or boundary-layer developments over different portions of a multi-element airfoil in a multipoint fashion. In addition, geometric parameters such as airfoil thickness and camber for each element can be specified. The design method uses a hybrid approach to determine the shapes of the individual elements that satisfy these design specifications. Each element of the multi-element airfoil is generated using an inverse code for isolated airfoil design. A two-dimensiona l panel method is used to obtain the velocity distributions over the resulting multi-element airfoil in inviscid flow. A direct integral boundary-layer method is then used to obtain the boundary-layer development over the multi-element airfoil. Using Newton iteration, the velocity distributions over portions of the airfoils in isolation are then used as design variables to achieve the velocity and the boundary-layer specifications on the multi-element airfoil. A key feature of the method is a novel scheme developed for rapid computation of the sensitivities for the Newton iteration. As demonstrated in the paper, this scheme results in significant reductions in computation time. Nomenclature Ci = airfoil lift coefficient (chord = 1)
Dielectric and Viscoelastic Responses of Imidazolium-Based Ionomers with Different Counterions and Side Chain Lengths

A molecular-level understanding of dynamics in imidazolium-based ionomers with different counterions and side chain lengths was investigated using X-ray scattering, oscillatory shear, and dielectric relaxation spectroscopy (DRS). Variations of the counterion size and side chain length lead to changes in glass transition temperature (Tg), extent of ionic aggregation, and dielectric constant, with consequences for ion transport. A physical model of electrode polarization is used to determine the number density of simultaneously conducting ions and their mobility. Imidazolium-based ionomers with larger counterion and longer side chain have lower Tg, resulting in higher ionic conductivity and mobility. The ionic mobility is coupled to ion motions that are directly measured as a second segmental process in DRS, as these are observed to share the same Vogel temperature. Time–temperature superposition (tTS) was applied to create linear viscoelasticity master curves and to investigate the delay in chain motion re...
Some empirical qualifications to the arguments for an argumentative theory

The empirical research on the psychology of argumentation suggests that people are prone to fallacies and suboptimal performance in generating, comprehending, and evaluating arguments. Reasoning and argumentation are interrelated skills that use many of the same cognitive processes. The processes we use to convince others are also used to convince ourselves. Argumentation would be ineffective if we couldn't reason for ourselves.
Redox chemistry of a binary transition metal oxide (AB2O4): a study of the Cu(2+)/Cu(0) and Fe(3+)/Fe(0) interconversions observed upon lithiation in a CuFe2O4 battery using X-ray absorption spectroscopy.

Copper ferrite, CuFe2O4, is a promising candidate for application as a high energy electrode material in lithium based batteries. Mechanistic insight on the electrochemical reduction and oxidation processes was gained through the first X-ray absorption spectroscopic study of lithiation and delithiation of CuFe2O4. A phase pure tetragonal CuFe2O4 material was prepared and characterized using laboratory and synchrotron X-ray diffraction, Raman spectroscopy, and transmission electron microscopy. Ex situ X-ray absorption spectroscopy (XAS) measurements were used to study the battery redox processes at the Fe and Cu K-edges, using X-ray absorption near-edge structure (XANES), extended X-ray absorption fine structure (EXAFS), and transmission X-ray microscopy (TXM) spectroscopies. EXAFS analysis showed upon discharge, an initial conversion of 50% of the copper(II) to copper metal positioned outside of the spinel structure, followed by a migration of tetrahedral iron(III) cations to octahedral positions previously occupied by copper(II). Upon charging to 3.5 V, the copper metal remained in the metallic state, while iron metal oxidation to iron(III) was achieved. The results provide new mechanistic insight regarding the evolution of the local coordination environments at the iron and copper centers upon discharging and charging.
Continuous Contact B Abdominal Scanning with Photographic Recording from a Non-Storage Oscilloscope on 70 MM Film

This presentation will describe and illustrate a technique for improving the resolution of abdominal contact B scanning and decreasing time required for the examination. In brief, the technique is as follows: the transducer is manually rapidly moved in a linear motion back and forth over the abdominal region being examined while the entire scanner arm is continuously moved to the right or left by the motor operated traverse mechanism. The resultant scanning pattern is a raster arrangement with each scan being produced in 1–2 seconds, and separated by approximately 3–5 mm from the adjacent scan. Two oscilloscopes are employed; a non-storage one for image recording upon which a 70 mm hand operated camera is mounted, and a storage scope for image viewing. With the camera shutter kept open during the entire scan sequence, the film is rapidly advanced at the end of each transducer pass over the abdomen. At the same time the image on the storage scope is erased. Thus, as the operator rapidly views a series of images briefly on the storage scope, the images are recorded on the 70 mm camera from the non-storage scope. This procedure requires the coordinated effort of two persons, one to perform the scanning and erasing of the storage oscilloscope and the second person to advance the 70 mm camera.
Aquatic Insect Ecology

Publisher Summary Aquatic insects are abundant in most freshwater habitats and often exhibit high diversity. In aquatic food webs, they serve as food items for nearly the full range of vertebrate and invertebrate predators, and many function as predators themselves. This chapter provides a brief overview of: constraints on aquatic insect species diversity, life history, and community structure; the role of aquatic insects in ecosystem processes; the impact of land use, climate change, and disturbances on their communities; and the utility of aquatic insects in biomonitoring studies. The review encompasses both lentic and lotic habitats, as well as a brief coverage of saline habitats. The discussion is placed in the context of how physical and life history factors constrain the distribution and abundance of aquatic insects, thereby altering communities and ecosystem function.
Business Strategy and Firm Performance: The Moderating Role of Product Market Competition

Despite the advanced knowledge on the importance of organizational strategy, empirical research present mixed results on the effect of strategic orientation on organizational performances. To address this conundrum, we operationalize the Miles and Snow (1978, 2003) business strategy typology by constructing a strategy index and explore the relation between strategy type (defenders, analyzers, and prospectors) and firm performance. We show consistent superior performance of defenders against analyzers and prospectors. However, as market concentration increases, the performance advantage of defenders declines, suggesting a moderating role of product market competition in the strategy-performance link. Using import tariff reductions in the U.S. manufacturing industries between 1974 and 2005 as exogenous shocks to product market competition, we conduct a difference-in-difference test and document a significant shift in strategic orientations as market competitiveness increases. These findings highlight the dynamic nature of business strategy and the importance of aligning business strategy with its environments.
Strategic Management and the Exploration of Diversity

The field of Strategic Management has had as a primary mission the analysis of diversity of performance among firms. While most research in the field has shared this common agenda, the approach taken has varied. Researchers have tended to be divided by the level of analysis with which they approach the issue and by their assumptions about the rationality of individuals and firms. This essay applies an evolutionary perspective to explore this question of diversity. It is suggested that such a perspective not only is an useful means with which to approach this question, but that as a by-product it may help to unify the strategy literature which has faced these methodological divisions based on level of analysis and assumptions of individual and firm rationality.
The Lipocalin LPR-1 Cooperates with LIN-3/EGF Signaling To Maintain Narrow Tube Integrity in Caenorhabditis elegans .

Lipocalins are secreted cup-shaped glycoproteins that bind sterols, fatty acids, and other lipophilic molecules. Lipocalins have been implicated in a wide array of processes related to lipophilic cargo transport, sequestration, and signaling, and several are used as biomarkers for human disease, but the functions of most lipocalins remain poorly understood. Here we show that the Caenorhabditis elegans lipocalin LPR-1 is required to maintain apical membrane integrity and a continuous lumen in two narrow unicellular tubes, the excretory duct and pore, during a period of rapid lumen elongation. LPR-1 fusion protein is expressed by the duct and pore and accumulates both intracellularly and in apical extracellular compartments, but it can also function cell nonautonomously when provided from outside of the excretory system. lpr-1 mutant defects can be rescued by increased signaling through the epidermal growth factor (EGF)-Ras-extracellular signal regulated kinase (ERK) pathway, which promotes the more elongated duct vs. less elongated pore tube fate. Spatial and temporal rescue experiments indicate that Ras signaling acts within the duct and pore tubes during or prior to cell fate determination to bypass the requirement for LPR-1. lpr-1 mutations did not disrupt LIN-3/EGF-dependent duct-fate specification, prevent functioning of any specific LIN-3/EGF isoform, or alter LET-23/EGFR localization, and reduced signaling did not phenocopy or enhance lpr-1 mutant defects. These data suggest that LPR-1 protects lumen integrity through a LIN-3/EGF-independent mechanism, but that increased signaling upregulates some target(s) that can compensate for lpr-1 absence.
An Unending Quest for Russia's Place in the World: The Discursive Co-evolution of the Study and Practice of International Relations in Russia:

The idea of ‘Global IR’ generated a growing interest in ‘national schools’ of IR and their contribution to understanding the diversity of international relations. As a part of this discussion, the ...
Fut2−/− (Non-Secretor) Mice Exhibit High Vwf Levels.

Abstract 2184 Levels of the critical adhesive glycoprotein von Willebrand Factor (VWF) are widely variable in human populations. Two-thirds of VWF variation is heritable, of which one-third is due to the carbohydrate blood group ABO. Another closely related carbohydrate blood group, Secretor (FUT2), has also been reported to influence VWF levels, but this association is controversial. In humans, FUT2 nonsense mutations are common and result in the loss of FUT2 enzyme activity and the absence of Lewis and ABH sugars in mucosal secretions, hence the designation of FUT2 null individuals as “non-Secretors”. The FUT2 (Secretor) fucosyltransferase makes H antigen (fucalpha1a2betagal) in mucosal tissues, which can subsequently be fucosylated by other Lewis enzymes (FUT3, FUT6, etc.) to generate the variations within the Lewis blood groups system, or serve as a substrate for the ABO glycosyltransferase to generate ABH structures. To investigate the hypothesis that Secretor influences VWF, we examined Vwf levels in Fut2 knock-out (non-Secretor) mice. The Fut2 knock-out mouse line backcrossed >20 generations to C57BL6/J was recovered from cryopreserved stock at the Jackson Laboratory. Eight to 12 week old male mice were selected for study to avoid the potential effects of estrous and aging on Vwf levels. Platelet-poor plasma was obtained from Fut2−/− (non-Secretor, n=7) and their Fut2+/+ (Secretor, n=5) littermates and assayed for Vwf antigen (Vwf:Ag) by sandwich ELISA using polyclonal anti-VWF antibodies [rabbit anti-human VWF (Dako); sheep anti-human VWF (Abcam)] and a pooled C57BL6/J plasma standard. Non-Secretor (Fut2−/−) animals exhibited Vwf:Ag levels nearly double those of their Secretor (Fut2+/+) littermates (p Disclosures: No relevant conflicts of interest to declare.
Tarik Cyril Amar. The Paradox of Ukrainian Lviv: A Borderland City Between Stalinists, Nazis, and Nationalists

Book review of Tarik Cyril Amar. The Paradox of Ukrainian Lviv: A Borderland City Between Stalinists, Nazis, and Nationalists. Cornell UP, 2015. xii, 356 pp. Illustrations. Bibliography. Index. $35.00, cloth.
Impact of hypoxia on gene expression patterns by the human pathogen, Vibrio vulnificus, and bacterial community composition in a North Carolina estuary

Estuarine environments are continuously being shaped by both natural and anthropogenic sources which directly/indirectly influence the organisms that inhabit these important niches on both individual and community levels. Human infections caused by pathogenic Vibrio species are continuing to rise, and factors associated with global climate change have been suggested to be impacting their abundance and geographical range. Along with temperature, hypoxia has also increased dramatically in the last 40 years, which has led to persistent dead zones worldwide in areas where these infections are increasing. Thus, utilizing membrane diffusion chambers, we investigated the impact of in situ hypoxia on the gene expression of one such bacterium, Vibrio vulnificus, which is an inhabitant of these vulnerable areas worldwide. By coupling these data with multiple abiotic factors, we were able to demonstrate that genes involved in numerous functions, including those involved in virulence, environmental persistence, and stressosome production, were negatively correlated with dissolved oxygen. Furthermore, comparing 16S ribosomal RNA, we found similar overall community compositions during both hypoxia and normoxia. However, unweighted beta diversity analyses revealed that although certain classes of bacteria dominate in both low- and high-oxygen environments, there is the potential for quantitative shifts in lower abundant species, which may be important for effective risk assessment in areas that are becoming increasingly more hypoxic. This study emphasizes the importance of investigating hypoxia as a trigger for gene expression changes by marine Vibrio species and highlights the need for more in depth community analyses during estuarine hypoxia.
PRESERVING SENIOR HOUSING IN A CHANGING CITY: REFLECTIONS ON A COALITION’S EFFORTS.

AbstractThe revitalization of Detroit, Michigan’s urban core has invigorated interest to live in these areas of the city. An unintended consequence has been the displacement of seniors whose low-income housing is being converted to market rate apartments. A coalition, Senior Housing Preservation-Detroit, formed to address immediate needs of older adults and advocate for policies that promote a city for all ages and income levels. This presentation offers reflections on lessons learned in the coalition’s history, including concerns of membership, messaging, mission and goals and tangible outcomes. One lesson learned was to gain the coalition members’ views on development, and fit goals of the coalition within these views. Excerpts from the documentary as well as related research (n=43) will be featured. This presentation will conclude with next steps for preserving senior housing in Detroit, and how this coalition’s efforts may be aligned with other preservation efforts around the United States.
Left Gastric Artery Lymph Nodes Should Be Included in D1 Lymph Node Dissection in Gastric Cancer.

The Japanese Classification of Gastric Carcinoma includes the left gastric artery (#7) lymph nodes (LNs) in the recommended extent of D1 LN dissection, but this recommendation has not been validated in western institutions. We reviewed data from a prospectively maintained database of gastric cancer patients who underwent resection at our academic cancer center and had a separate pathologic assessment of #7 LN in 2005–2016. Risk factors for #7 LN metastases and overall survival were examined by uni- and multivariable analyses. We identified 173 patients; 114 (66%) were treated with preoperative therapy, most commonly with chemoradiation therapy (47%, 81/173). We identified 22 patients (13%) who had #7 LN metastases, which accounted for 35% (22/63) of node-positive patients. No preoperative factors were associated with #7 LN metastases by univariable analyses. Patients with #7 metastases were not associated with shorter overall survival after adjustment by nodal stage (hazard ratio 1.49, 95% confidence interval 0.67–3.32; p = 0.33). Metastasis to #7 LN station was common in gastric cancer, but the survival impact was not significant after adjustment by nodal stage. We conclude that #7 LNs should be routinely dissected in gastric cancer patients, and this station should be included within the extent of D1 LN dissection.
Basic Response Functions of Simple Inertoelastic and Inertoviscous Models

AbstractMotivated by the growing interest in suppressing vibrations with supplemental rotational inertia, this paper examines and constructs the basic frequency-response functions and subsequently ...
Cancer-associated arginine-to-histidine mutations confer a gain in pH sensing to mutant proteins

The intracellular pH (pHi) of most cancers is constitutively higher than that of normal cells and enhances proliferation and cell survival. We found that increased pHi enabled the tumorigenic behaviors caused by somatic arginine-to-histidine mutations, which are frequent in cancer and confer pH sensing not seen with wild-type proteins. Experimentally raising the pHi increased the activity of R776H mutant epidermal growth factor receptor (EGFR-R776H), thereby increasing proliferation and causing transformation in fibroblasts. An Arg-to-Gly mutation did not confer these effects. Molecular dynamics simulations of EGFR suggested that decreased protonation of His776 at high pH causes conformational changes in the αC helix that may stabilize the active form of the kinase. An Arg-to-His, but not Arg-to-Lys, mutation in the transcription factor p53 (p53-R273H) decreased its transcriptional activity and attenuated the DNA damage response in fibroblasts and breast cancer cells with high pHi. Lowering pHi attenuated the tumorigenic effects of both EGFR-R776H and p53-R273H. Our data suggest that some somatic mutations may confer a fitness advantage to the higher pHi of cancer cells.
The Relationship between Marbling, Superoxide Dismutase, and Beef Tenderness

ObjectivesIt is known that excessive fat deposition (obesity) in humans induces metabolic stress, resulting in excessive production of reactive oxygen species (ROS). Perhaps ROS are responsible for tenderness differences between high and low marbled cattle. Our hypothesis is that marbling deposition is an indication of excessive energy intake, and excessive energy intake has been identified as a source of oxidative stress in livestock. Oxidative stress might enhance postmortem proteolysis and lead to more tender beef, resulting in the phenomenon we observe with Prime beef being more tender than Select beef. Superoxide dismutase (SOD) helps combat ROS by converting superoxide, the most potent ROS, into less toxic forms of oxygen, which are further broken down by other enzymes. Our objective was to identify the relationship between quality grade, tenderness, and SOD activity.Materials and MethodsBeef strip loins (n = 36 Prime and n = 36 Select) were randomly selected and aged for 2, 7, 14, 21, and 28 d postmortem. Each strip loin was cut into one 1.27 cm lab sample and 5 individual 2.54 cm steaks, and each steak was randomly assigned to 1 of the 5 aging periods. Six cores were taken from each cooked steak and analyzed for tenderness using Warner-Bratzler shear force. The lab sample was aged for 2 d postmortem, powdered and stored at –80°C for SOD analysis.ResultsPrime steaks were significantly more tender (p < 0.0001) than Select steaks. Steaks from 14, 21, and 28 d of aging, were more tender than Day 7 (p = 0.02) steaks, and d 7 steaks were more tender than d 2 samples (p = 0.0001). There tended to be an interaction (p = .13) between age and quality grade with Select grade steaks exhibiting a greater decline in shear force. No significant interaction between quality grade and SOD activity was observed (p = 0.69).ConclusionThese results suggest that the differences in quality grade and tenderness cannot be explained by the changes in SOD. Further exploration for other ROS species and enzyme inhibitors, such as catalase and glutathione, would be useful to examine if ROS are influential in tenderness.
THE REGIONAL SECURITY COMPLEX OF SOUTH AMERICA: AN ANALYSIS FROM THE SOUTH AMERICAN DEFENSE COUNCIL OF UNASUR

Este artigo e resultado de uma investigacao sobre o modelo de Complexo de Regional de Seguranca (CRS) existente na America do Sul, em especial a partir da criacao do Conselho de Defesa Sul-Americano (CDS), no âmbito da UNASUL – Uniao das Nacoes Sul-Americanas. A partir de uma discussao teorica sobre os Complexos Regionais de Seguranca, argumenta-se que a experiencia sul-americana recente afirmou um modelo de “tipo extra”, na medida em que sua dinâmica nao se identifica com a presenca de uma potencia regional com atuacao proeminente em nivel global, apesar da maior expressao economica brasileira nos contextos regional e internacional.
In vivo wound healing response to a modified degradable fibrin scaffold.

Pooled donor fibrin with an ultimate fibrinogen concentration of 60 mg/ml was used to study its effect on wound healing of surgically created ulcers in a rabbit ear. Water soluble polymer (PEG Mw = 20 KD) beads of 100-150 μm were added (12% by volume) to the fibrinogen to obtain a porous and rough structure. Five 6 mm-diameter ulcers to the depth of bare cartilage were created on each rabbit ear. There were two periods of study (4 and 8 days), with 15 ulcers in each time period, 5 of which were treated with a modified fibrin scaffold, 5 with a non-modified fibrin scaffold, and 5 served as control ulcers. The ulcer sites were subjected to routine histological processing and histomorphometrical quantification. Data analysis revealed significant increases in volume fraction of fibroblast and number of blood vessels in the modified fibrin scaffold treated ulcers over control and non-modified fibrin scaffold treated groups.
DQB1*0602 and DQA1*0102 (DQ1) Are Better Markers Than DR2 for Narcolepsy in Caucasian and Black Americans

In the present study, we tested 19 Caucasian and 28 Black American narcoleptics for the presence of the human leucocyte antigen (HLA) DQB1*0602 and DQA1*0102 (DQ1) genes using a specific polymerase chain reaction (PCR)-oligotyping technique. A similar technique was also used to identify DRB1*1501 and DRB1*1503 (DR2). Results indicate that all but one Caucasian patient (previously identified) were DRB1*1501 (DR2) and DQB1*0602/DQA1*102 (DQ1) positive. In Black Americans, however, DRB1*1501 (DR2) was a poor marker for narcolepsy. Only 75% of patients were DR2 positive, most of them being DRB1*1503, but not DRB1*1501 positive. DQB1*0602 was found in all but one Black narcoleptic patient. The clinical and polygraphic results for this patient were typical, thus confirming the existence of a rare, but genuine form of DQB1*0602 negative narcolepsy. These results demonstrate that DQB1*0602/DQA1*0102 is the best marker for narcolepsy across all ethnic groups.
WHY EMERGING BUSINESS MODELS AND NOT COPYRIGHT LAW ARE THE KEY TO MONETISING CONTENT ONLINE

Presented at the First International Forum on the Content Industry: Legal and Policy Framework for the Digital Content Industry collaboratively held by the East China University of Political Science and Law (http://www.ecupl.edu.cn) and the Queensland University of Technology (http://www.qut.edu.au) in Shanghai, People’s Republic of China, May 2007. This publication is an output of the ARC Centre of Excellence for Creative Industries and Innovation (http://www.cci.edu.au) Queensland University of Technology.
Ethical Issues Related to Mohs Skin Cancer Surgery

Although legal considerations can arise in the performance of any aspect of a dermatology practice, they are more likely to occur in the areas of diagnosis and treatment of skin cancers. Although there is no substantiated data about dermatologic skin cancer litigation, and specifically Mohs surgery, there are anecdotal suggestions that such malpractice claims have increased. Mohs surgeons, often performing some of the most complex skin cancer treatments, are clearly at risk for both ethical and legal issues related to their treatment. This chapter will look at the interplay between legal and ethical issues with an emphasis on those issues that specifically can arise in the practice of Mohs surgery.
Modeling Zika Virus Spread in Colombia Using Google Search Queries and Logistic Power Models

Public health agencies generally have a small window to respond to burgeoning disease outbreaks in order to mitigate the potential impact. There has been significant interest in developing forecasting models that can predict how and where a disease will spread. However, since clinical surveillance systems typically publish data with a lag of two or more weeks, there is a need for complimentary data streams that can close this gap. We examined the usefulness of Google Trends search data for analyzing the 2016 Zika epidemic in Colombia and evaluating their ability to predict its spread. We calculated the correlation and the time delay between the reported case data and the Google Trends data using variations of the logistic growth model, and showed that the data sets were systematically offset from each other, implying a lead time in the Google Trends data. Our study showed how Internet data can potentially complement clinical surveillance data and may be used as an effective early detection tool for disease outbreaks.
Hybrid breast reconstruction—the best of both worlds

The two common reconstructive modalities following mastectomy include implant-based reconstruction and autologous reconstruction. While the majority of patients can be successfully treated with either one of these approaches, a subset of patients will benefit from a third reconstructive approach which combines implant-based and autologous reconstruction, i.e., hybrid reconstruction. Here, the authors discuss indications, surgical technique, results and additional reconstructive considerations of combining free abdominal tissue transfer with simultaneous implant placement. A reconstructive algorithm is presented.
Implementation and Evaluation of Bi-Directional WiFi Back-channel Communication

This paper presents implementation and validation of innovative back-channel wireless communication techniques for ultra-low power (ULP) devices. Back-channel schemes allow ULP devices that are not WiFi-compliant to communicate with already-deployed WiFi infrastructure without any hardware modification. This paper introduces an improved payload bit crafting procedure to create back-channel messages embedded in standard WiFi OFDM packets. In addition, the concept of bi-directional WiFi back-channel is newly introduced and validated in the prototype system. Using a commercial WiFi chip and Universal Software Radio Peripheral (USRP) X310 hardware platform, two downlink back-channel schemes as well as an uplink back-channel scheme are successfully demonstrated rendering realistic real-time communication performance. Field trials are performed for over-the-air wireless back-channel bi-directional communications. System characterization confirms that the proposed back-channel can operate at lower signal-to-noise ratio than what standard WiFi systems require.
A Comparative Analysis of Two Commercial Digital Photogrammetry Software for Cultural Heritage Applications

The paper seeks to evaluate the literature on digital photogrammetry processing software, comparing Agisoft Photoscan (now known as Agisoft Metashape, beginning with version 1.5) RealityCapture and to test the two programs in a real-world situation to further examine the difference in the software and resulting model. Tests were carried out for the evaluation of Photoscan, and RealityCapure—two European based digital photogrammetry programs—using the same artifact and data in all three tests. The artifact is part of the Farid Karam Collection of Antiquities, housed at the University of South Florida (USF) Libraries Tampa Special Collections. The chosen artifact for study, the aryballos inv. no. 68, was captured in ideal conditions to better evaluate multiple programs with the same data. The digital artifact was examined based upon knowledge and photographs of the physical artifact and evaluated relatively and comparatively between the programs.
Hepatic Glucagon Signaling Regulates PCSK9 and Low-Density Lipoprotein Cholesterol.

Rationale: Glucagon is a key hormone that regulates the adaptive metabolic responses to fasting. In addition to maintaining glucose homeostasis, glucagon participates in the regulation of cholester...
How social media discourses organize communication online: a multi-level discursive analysis of tensions and contradictions in teens’ online experiences

Media reports frequently frame youth as foolish but also uniquely vulnerable when it comes to social media. However, adult framings of teen online activities and teens’ reported experiences regular...
Heat elution: a modification of the Landsteiner-Miller method.

CONCLUSIONS Elution removes antibodies coating red blood cells and allows for serologic testing of the recovered antibodies. Heat elution may be used in the investigation of ABO hemolytic disease of the fetus and newborn, in the detection of weak A and B antigens in combination with adsorption-elution using polyclonal antibodies, and for the resolution of interfering IgM agglutinating antibodies.
Variation in the seasonal germination niche across an elevational gradient: the role of germination cueing in current and future climates.

Author(s): Gremer, Jennifer R; Chiono, Alec; Suglia, Elena; Bontrager, Megan; Okafor, Lauren; Schmitt, Johanna | Abstract: PREMISE:The timing of germination has profound impacts on fitness, population dynamics, and species ranges. Many plants have evolved responses to seasonal environmental cues to time germination with favorable conditions; these responses interact with temporal variation in local climate to drive the seasonal climate niche and may reflect local adaptation. Here, we examined germination responses to temperature cues in Streptanthus tortuosus populations across an elevational gradient. METHODS:Using common garden experiments, we evaluated differences among populations in response to cold stratification (chilling) and germination temperature and related them to observed germination phenology in the field. We then explored how these responses relate to past climate at each site and the implications of those patterns under future climate change. RESULTS:Populations from high elevations had stronger stratification requirements for germination and narrower temperature ranges for germination without stratification. Differences in germination responses corresponded with elevation and variability in seasonal temperature and precipitation across populations. Further, they corresponded with germination phenology in the field; low-elevation populations germinated in the fall without chilling, whereas high-elevation populations germinated after winter chilling and snowmelt in spring and summer. Climate-change forecasts indicate increasing temperatures and decreasing snowpack, which will likely alter germination cues and timing, particularly for high-elevation populations. CONCLUSIONS:The seasonal germination niche for S. tortuosus is highly influenced by temperature and varies across the elevational gradient. Climate change will likely affect germination timing, which may cascade to influence trait expression, fitness, and population persistence.
A short history of Zionist and Israeli political Marxism

In this article, I argue that despite seemingly intractable disagreements between different Zionist and Israeli political Marxists, they share a common theoretical and political perspective, which ...