cssi/SciSciGPT-SciSciNet huggingface dataset:
A Tale of Two Mommies: (Re)Storying Family of Origin Narratives

ABSTRACTThis study examined co-mother family of origin stories. Origin stories, representing the formation of a family, are culturally understood within a master narrative of heterosexual love and biological childbearing. Beginnings of co-mother families rupture this dominant, gendered, boy-meets-girl script. Investigating whether or not co-mother stories reify the normative master narrative or if instead their narrations resist and/or possibly transform conventional understandings, analysis identified three co-mother origin story themes: Becoming a Family (1) as Normal, (2) as Negotiation, and (3) as Normalization. Themes differ in terms of depiction of co-mother family formation as congruent with current norms, as something that needs to be made to seem normal (i.e., in need of normalization), or as something between normal and normalization—to be negotiated internally within the couple. Study results are discussed within a broader framework of family coming-together stories.
Cyclosporine and Plasma Exchange Is Superior to Corticosteroids and Plasma Exchange as Initial Therapy of TTP.

Patients with a clinical diagnosis of TTP presenting to The Ohio State University between April 2003 and July 2005 were enrolled and treated on one of two consecutive, prospective clinical trials. The first study treated patients with concurrent corticosteroids and plasma exchange(PE), with the second study using concurrent cyclosporine(CSA) and PE as initial therapy. Patients: Eleven patients categorized as idiopathic TTP were enrolled on the corticosteroid/PE study and 5 patients (4 idiopathic, 1 SLE associated) have been enrolled to date on the concurrent CSA/PE study. Complete demographic data for both study populations is shown in Table 1. Methods: Patients treated on the corticosteroid/PE study received prednisone (1 mg/kg/day) concurrent with daily plasma exchange therapy until remission was achieved. After remission, patients tapered the corticosteroids over 4 weeks. Patients enrolled on the CSA/PE study received CSA (2–3 mg/kg/day) concurrent with PE until remission was achieved. CSA was then continued for a total of 6 months of therapy and discontinued. Serial measurements of ADAMTS13 activity and inhibitors were obtained prior to therapy, after remission was achieved and PE discontinued, and serially throughout follow-up. Results: Nine of 11 patients achieved remission with concurrent corticosteroids and PE, with 2 patients refractory to therapy. Six of the 9 patients achieving remission suffered a recurrence of TTP within 30 days of tapering PE, and while still taking corticosteroids. In contrast, all 5 patients treated with concurrent CSA/PE achieved a remission with no patients suffering a recurrence within 30 days of tapering PE. More importantly, patients treated with concurrent corticosteroids/PE had an increase in median inhibitor titer (338 ug/ml to 1550 ug/ml) after successful treatment with corticosteroids/PE, in contrast to the CSA/PE treated patients that had a significant decrease in median inhibitor titer (2325 ug/ml to 1265 ug/ml) after therapy. This decrease in ADAMTS13 inhibitors after CSA/PE treatment compared to the corticosteroids/PE treated patients was found to be statistically significant (p=0.05) by the exact Wilcoxon Rank Sum Test. Conclusions: The CSA/PE treated patients compared to the corticosteroid/PE treated patients had a statistically significant decrease in the inhibitor titer. This may in part explain the improvement in remission rate and 30-day recurrence rate seen with the CSA/PE treated patients.
Automatically mapping and integrating multiple data entry forms into a database

Forms are a standard way of gathering data into a database. Many applications need to support multiple users with evolving data gathering requirements. It is desirable to automatically link dynamic forms to the back-end database. We have developed the FormMapper system, a fully automatic solution that accepts user-created data entry forms, and maps and integrates them into an existing database in the same domain. The solution comprises of two components: tree extraction and form integration. The tree extraction component leverages a probabilistic process, Hidden Markov Model (HMM), for automatically extracting a semantic tree structure of a form. In the form integration component, we develop a merging procedure that maps and integrates a tree into an existing database and extends the database with desired properties. We conducted experiments evaluating the performance of the system on several large databases designed from a number of complex forms. Our experimental results show that the FormMapper system is promising: It generated databases that are highly similar (87% overlapped) to those generated by the human experts, given the same set of forms.
Heating Curves During Commercial Cooking of the Blue Crab

Blue crabs are cooked in steam retorts or boiling water baths to assist in removing the meat from the shell. As a first step in determining if spores of Clostridium botulinum would survive the process, internal crab temperatures were measured during cooking in commercial plants. Tests were done in six states. Crabs were instrumented with thermocouples, and heating curves were recorded during normal commercial processing. The lowest terminal heating temperature achieved in an instrumented crab during steam retorting was 208 F; however, this temperature remained above 180 F for 4 min. In the boiling water bath, the terminal heating temperature was slightly lower (205 F) but the time above 180 F was longer (11 min).
Strategies for Implementing the National Standards for Culturally and Linguistically Appropriate Services in Home Health Care

This article is an abridged version of a book chapter, Culturally and Linguistically Appropriate Services, published in the Handbook of Home Health Care Administration, Sixth Edition (Marilyn Harris, editor). The article describes the importance of culturally and linguistically competent care for the success of home health agencies. It uses the 15 standards of the National Standards for Culturally and Linguistically Appropriate Services in Health and Health Care (CLAS Standards) as an outline for identifying strategies that home health leaders can incorporate into their agencies’ practices to enhance their care to culturally and linguistically diverse patients. Providing services that produce equitable outcomes for diverse patients is likely to enhance agency Home Health Compare and HHCAHPS (Home Health Care Consumer Assessment of Healthcare Providers and Systems) scores, Star Ratings, and reimbursement in a value-based reimbursement model.
The Role of Porosity-Graded Electrode in Mitigating Performance Degradation of High Voltage Lithium-Ion Battery

LiNi0.5Mn1.5O4 (LNMO) is one of the high potential cathodes for lithium-ion batteries due to the high operating voltage (4.7 V vs. Li) and high specific energy (650Whkg-1). However, severe accelerated performance degradations occurring especially at the interface between electrode and electrolyte, hinder the implementation of the LNMO. In this work, porosity-graded electrodes are designed to mitigate LNMO degradation. The LNMO was synthetized via solid-state reaction. X-ray powder diffraction (XRD) and scanning electron microscope (SEM) were utilized in this study. The increase in porosity can improve the conductivity and diffusivity of lithium-ions through the electrode. In addition, solid electrolyte interphase (SEI) formation can be varied and controlled when the porosity is different inside the electrode. The test results showed, comparing with conventional single-layer electrode, the double-layer porosity-graded LNMO cathode reduced the capacity fade about 8.285% for full cell and 5.29% for half-cell, respectively.
180nm HVIC technology for digital AC/DC power conversion

A new high-voltage integrated circuit (HVIC) technology has been developed and optimized for AC/DC power conversion applications that require increased digital content. This cost-effective process uses 3.3V CMOS and a 180nm backend process to provide about 10X greater digital circuit density compared to conventional 0.5um 5V CMOS solutions. Excellent analog circuit performance is maintained. For the first time, reliable 700V devices are demonstrated using shallow trench isolation (STI) oxide over a double-RESURF drift region.
Instrumentation for cryogenic magic angle spinning dynamic nuclear polarization using 90 L of liquid nitrogen per day

Cryogenic sample temperatures can enhance NMR sensitivity by extending spin relaxation times to improve dynamic nuclear polarization (DNP) and by increasing Boltzmann spin polarization. We have developed an efficient heat exchanger with a liquid nitrogen consumption rate of only 90L per day to perform magic-angle spinning (MAS) DNP experiments below 85K. In this heat exchanger implementation, cold exhaust gas from the NMR probe is returned to the outer portion of a counterflow coil within an intermediate cooling stage to improve cooling efficiency of the spinning and variable temperature gases. The heat exchange within the counterflow coil is calculated with computational fluid dynamics to optimize the heat transfer. Experimental results using the novel counterflow heat exchanger demonstrate MAS DNP signal enhancements of 328±3 at 81±2K, and 276±4 at 105±2K.
Draft Genome Sequences of Three Coxiella burnetii Strains Isolated from Q Fever Patients.

ABSTRACT In the current study, we determined the draft genome sequences of three Coxiella burnetii human disease isolates. The Coxiella burnetii Turkey (RSA315) and Dyer (RSA345) strains were isolated from acute Q fever patients, while the Ko (Q229) strain was isolated from a Q fever endocarditis patient.
Neoplastic Nodular B-Cell Pattern

Cutaneous B-cell lymphomas encompass a group of B-cell lymphomas that presents in the skin without evidence of extra-cutaneous disease at the time of initial diagnosis; thus, complete laboratory workup and imaging studies are necessary. In 2005 a new consensus classification for cutaneous lymphoma was introduced by the World Health Organization (WHO) and the European Organization for Research and Treatment of Cancer (EORTC). This classification has resulted in a significant improvement on categorization of cutaneous B-cell lymphoma and unified criteria for therapeutic trials. This chapter focuses on primary cutaneous follicle center lymphoma; primary cutaneous marginal zone B-cell lymphoma; cutaneous plasmacytoma; primary cutaneous large B-cell lymphoma, leg type; and other primary cutaneous large B-cell lymphomas including plasmablastic lymphoma and primary cutaneous T-cell/histiocyte-rich B-cell lymphoma.
Overdose Prevention Through Medical Treatment of Opioid Use Disorders

In their article, Larochelle and colleagues provided convincing evidence of the benefits of methadone and buprenorphine in preventing opioid-related deaths in patients with a history of nonfatal op...
Innovative fiber-reinforced polymer (FRP) composites for disaster-resistant buildings

Abstract: The chapter begins by discussing a new type of sandwich panel called composite structural insulated panels (CSIPs) intended to replace the traditional SIPs that are made of wood-based materials. A detailed analytical modeling procedure is presented in order to determine the global buckling, interfacial tensile stress at facesheet/core debonding, critical wrinkling stress at facesheet/core debonding, equivalent stiffness, and deflection for CSIPs. The proposed models were validated using experimental results that have been conducted on full-scale CSIP walls and floor panels. In order to be used as a hazard-resistant material, a detailed section was presented to show the resistance of CSIP elements to the different types of hazard effects, including impact loading, floodwater effect, fire effect, and windstorm loading.
Initial steps toward a new method of atmospheric characterization over long baseline arrays

Initial data for the current and ongoing experiment to measure and possibly predict the horizontal turbulent strength, C 2 N , of the atmosphere above the Magdalena Ridge Observatory Interferometer (MROI) is presented. C 2 N is a representation of the atmosphere’s ability to transport scalars and is measured using a set of Kipp and Zonen Large Aperature Scintillometers (LAS). LAS Calibration data as well as initial test data are presented and analyzed. Correlation techniques are used to determine the optimal method of C 2 N calculation from the first generation LAS. A 19-day test over the array site was conducted and analyzed using both Fourier and wavelet analysis and filtration. Frequency analysis showed few periodic features due to the quasi-periodic nature of the signal.
Clarifying the phylogenetic relationships and taxonomy of Stenonema, Stenacron and Maccaffertium, three common eastern North American mayfly genera.

Abstract Stenonema, Stenacron, and Maccaffertium are three closely related genera of mayflies (Ephemeroptera:Heptageniidae) commonly found across North America. Due to their primarily aquatic life history and sensitivity to aquatic pollutants, these mayflies are often used as water quality indicators. However, there is little morphological variation within these genera, leading to difficulties in identification and rampant taxonomic confusion, limiting their utility as bioindicators. In an attempt to resolve the phylogenetic relationships of Stenonema, Stenacron, and Maccaffertium, and to clarify their higher-level classifications, we sequenced regions of two mitochondrial genes (cytochrome oxidase subunit 1 (cox1) and 16S ribosomal RNA (rrnl)) and two nuclear genes (Wingless (Wg) and histone H3) from 60 individuals representing most of the described species in these genera and included data from representatives of three heptageniid genera (Kageronia, Macdunnoa and Pseudiron) proposed in previous studies to be closely related to our focal taxa as well as two more distantly related heptageniid genera (Epeorus and Heptagenia) to root the phylogenies. Maximum likelihood and Bayesian analysis were conducted on single-gene and concatenated multi-gene data sets and species tree methods were utilized to resolve relationships. These analyses resolved Stenacron as a monophyletic group sister to a clade comprising Macdunnoa, Maccaffertium and Stenonema. Maccaffertium was found to be paraphyletic, with Stenonema femoratum resolved within Maccaffertium as sister to M. mexicanum. Many relationships remained unresolved or varied across analyses, making revision of the classification based on phylogenetic considerations challenging. To minimize confusion while naming clades and acknowledging uncertainty in our phylogenetic conclusions, we redefine Stenonema to include Maccaffertium and propose three subgenera—Stenonema, Maccaffertium and Lewisa— for key well-supported clades.
Laparoscopic Radical Prostatectomy

Prostate cancer is the most frequently diagnosed solid organ tumor among men in the United States Radical prostatectomy is widely considered as the gold standard definitive treatment option for localized prostatic cancer, with excellent long-term (15-yr) cure rates. Therapeutic goals of radical prostatectomy are cancer cure, early return of continence, and preservation of sexual function. The anatomical radical retropubic prostatectomy described by Walsh (1) has gained acceptance as the standard open surgical technique
On Special Functions for Radiation From Sources Close to an Electrically Large Convex Surface

Several high frequency asymptotic methods in electromagnetics include Fock-type functions. Acoustic hard and soft Fock functions are used as special functions in asymptotic solutions for radiation from sources on an electrically large conducting convex surface. Formulations are available for accurate evaluation of these functions. Asymptotic solutions for radiation from sources close to an electrically large conducting convex surface include the derivatives of these Fock functions as well. However, the existing formulations for the functions do not yield accurate and continuous results for their derivatives. In this letter, the existing formulations are modified to adjust the boundaries between separate intervals for efficient and accurate evaluation of the Fock functions and their derivatives, and to assess continuity across the boundaries for different numbers of terms. The modified formulations are used in the extended uniform geometrical theory of diffraction solution to predict the radiation pattern of a quarter wavelength monopole antenna, which is validated in comparison with the results of the multilevel fast multipole method (MLFMM).
Case-Control Study of Cephalometrics in Patients with Moyamoya.

Objective To determine whether cranial metrics consistently differed between patients with moyamoya and age-, sex-, and race-matched controls. Methods Patients diagnosed with moyamoya disease by cerebral angiogram were obtained from a prospectively collected database through the Department of Neurosurgery at the University of Kansas Medical Center. Control patients matched by decade of age, sex, and race were collected through a deidentified hospital database by International Classification of Diseases-9 and 10 codes for ischemic stroke to identify patients with computed tomography angiograms. Imaging studies for both groups were analyzed to obtain 6 skull metrics: maximum anterior to posterior distance, maximum biparietal distance, bregma to occiput distance, right carotid canal diameter (CCD), left CCD, and cephalic index. Results Forty-five patients were identified in each cohort. Measurements of mean anterior to posterior skull diameter, mean biparietal skull diameter, bregma to occiput distances, and calculated cephalic index did not demonstrate a statistically significant difference between patients with moyamoya and control patients. Right carotid canal mean diameter was 4.8 mm for the moyamoya group and 5.4 mm for the control group, with a significant raw mean difference of −0.61 mm (95% confidence interval, −0.95 to −0.27). Left CCD was 4.7 mm for the moyamoya group and 5.5 mm for the control group, resulting in a significant raw mean difference of −0.76 mm (95% confidence interval, −1.09 to −0.43). Conclusions This study identified 2 skull parameters as statistically different in patients with moyamoya compared with a matched control group of patients with ischemic stroke: right CCD and left CCD.
Clinical treatment of congenital middle ear cholesteatoma in children

Objective:To summarize the clinical characteristics and clinical treatment of congenital cholesteatoma (CC) of the middle ear in children, provide early diagnosis methods and explore standardized diagnosis and treatment plan.Method:A retrospective chart review of 94 patients with a diagnosis of middle ear cholesteatoma, in Beijing Children's Hospital, between 2009 and 2015 was carried on. 14 patients with CC were identified using the criteria proposed by Levenson, and were divided into two groups according to the course of disease. The course of disease in group A was less than 3 months, and group B was more than 3 months. The main complains, diagnostic methods and Potsic's stage of temporal bone CT findings were recorded.Result:①The age of 14 cases of congenital cholesteatoma of the middle ear ranged from 3.33 to 10.17 years, with the median age of 7.20 years. ②Hearing loss (13/14, 92.86%) was the most common complain. Finding methods included hearing screening and CT scan (11/14, 78.57%), tympanotomy (2/14, 14.28%) and otoscopic examination (1/14, 7.14%). ③There were 6 people in group A and 8 in group B. According to Potsic's grading standard, the difference between the two groups was statistically significant (P=0.043). ④The preoperative Air-Bone conduction threshold Gap (ABG) in A and B two groups were (38.10±7.43) dB and (42.09±9.96) dB, respectively, and there was no significant difference in analysis (P=0.427). ⑤The difference between pre-ABG and post-ABG ［(36.26±5.56）dB and （21.70±3.80）dB, P=0.004］ was significant. Canal wall up mastoidectomy was the preferred procedure and 11/14 (78.57%) patients had this surgery done.Conclusion:The shorter the course of disease, the lower the stage of cholesteatoma of the middle ear indicates the importance of early detection. But congenital cholesteatoma is more occult, and even within 3 months, cholesteatoma can cause severe damage to the hearing and middle ear structure. Early screening programs can recommend hearing screening and CT scan to facilitate early intervention.
Birefringence-based orientation mapping of cellulose nanofibrils in thin films

Determination of nanofibril orientation is crucial for predicting the properties of films and membranes made from cellulose nanofibrils (CNF) because of their inherent anisotropic nature. A novel method is proposed based on image analysis of the polarized light micrographs to quantify and map nanofibril orientation in the film structure. Thin films (average 30 µm in thickness) of CNF were produced using a filtration method and were wet-stretched to two extension levels. Randomly-oriented films were also produced as the control without applying stretch. Samples were imaged at − 45°, 0° and + 45° between crossed polarizers using a polarized light microscope. A BOI was developed based on the interference color changes between the two angles (+ 45° and − 45°). The proposed BOI values range between − 1 and + 1 differentiating orientation in perpendicular directions. The index was shown to work successfully for mapping of the fibril orientation in CNF films. Statistical analysis of the tensile test results confirmed significant difference between tensile modulus of CNF films produced using different stretch ratios. This difference was also supported by the good agreement between the tensile properties of the films, the BOI and directionality results obtained from the surface analysis of scanning electron micrographs. The method was validated by applying to single pulp fibers with known orientation as well as un-stretched and stretched polyvinyl chloride films and oriented cellulose nanocrystals. The advantages of the proposed method over other conventional methods used for orientation analysis are discussed.
A Clinical Trial of Isradipine: What Went Wrong?

The Parkinson Study Group STEADY-PD III Investigators reported the results of a randomized controlled trial evaluating the effect of isradipine, a dihydropyridine calcium-channel blocker, on clinic...
Mitigating Voltage Drop in Resistive Memories by Dynamic RESET Voltage Regulation and Partition RESET

The emerging resistive random access memory (ReRAM) technology has been deemed as one of the most promising alternatives to DRAM in main memories, due to its better scalability, zero cell leakage and short read latency. The cross-point (CP) array enables ReRAM to obtain the theoretical minimum 4F^2 cell size by placing a cell at the cross-point of a word-line and a bit-line. However, ReRAM CP arrays suffer from large sneak current resulting in significant voltage drop that greatly prolongs the array RESET latency. Although prior works reduce the voltage drop in CP arrays, they either substantially increase the array peripheral overhead or cannot work well with wear leveling schemes. In this paper, we propose two array micro-architecture level techniques, dynamic RESET voltage regulation (DRVR) and partition RESET (PR), to mitigate voltage drop on both bit-lines and word-lines in ReRAM CP arrays. DRVR dynamically provides higher RESET voltage to the cells far from the write driver and thus encountering larger voltage drop on a bit-line, so that all cells on a bit-line share approximately the same latency during RESETs. PR decides how many and which cells to reset online to partition the CP array into multiple equivalent circuits with smaller word-line resistance and voltage drop. Because DRVR and PR greatly reduce the array RESET latency, the ReRAM-based main memory lifetime under the worst case non-stop write traffic significantly decreases. To increase the CP array endurance, we further upgrade DRVR by providing lower RESET voltage to the cells suffering from less voltage drop on a word-line. Our experimental results show that, compared to the combination of prior voltage drop reduction techniques, our DRVR and PR improve the system performance by 11.7% and decrease the energy consumption by 46% averagely, while still maintaining >10-year main memory system lifetime.
Chapter Twenty-Four – Gas Chromatography

Publisher Summary This chapter describes gas chromatography as a technique whereby the components of a mixture in the gaseous state are separated as the sample passes over a stationary liquid or solid phase. Differences in the interactions between the sample components and the stationary phase account for the separation. Gas chromatography is fully developed and it is now applicable to almost every area within the physical and chemical sciences. The method has many advantages in that it can be used for qualitative and quantitative analyses, the time of analysis is short, the instrument is simple, the sensitivity is high, and the method is applicable to about 60% of the organic compounds known to man. The separations technique is very simple and straightforward with gas chromatography. The successful separation of cis and trans isomers, of oxygen isotopes, or of pesticides is a matter of choosing the proper column and conditions. The chapter also discusses chromatogram, instrument, and factors affecting separation.
Chinese Consumers’ Attitudes of Chinese Versus Western Fashion Brands: An Exploration of Possible Predictor Variables Related to Individual and Cultural Values: An Abstract

This paper reflects the conference theme regarding the evolution of the global marketplace, specifically, in China. Factors such as the rising middle class in China and transformations among the Chinese that instill more Westernized values shape how fashion brands and retail firms do business in China. It is necessary for marketers to consider the most effective means in targeting Chinese consumers and driving their purchasing behavior of fashion goods. This study explores the efficacy of “face-saving,” materialistic, and ethical values in predicting Chinese consumers’ attitudes toward Western and Chinese fashion brands.
Predictive Human-Machine Interface for Teleoperation of Air and Space Vehicles over Time Delay

Current plans for the exploration of Moon and Mars envision the use of telerobotic systems controlled from orbiting laboratories. The advantage of telerobotics is that it combines the resilience, endurance and precision of robots with the inherent flexibility, anticipation and decision making capabilities of humans. The primary disadvantage of telerobotics is the communication time delay in the human-robot control loop. The delay can lead to a loss of situation awareness, an increase in operator work load, and an overall decrease in effectiveness and efficiency of the human-robot system. Most of the effects of the delay can be mitigated by the use of predictive displays, presenting the operator with a simulated system state. This paper presents current work on such a predictive display designed to support an operator in remote flight and landing of space robots and unmanned aerial vehicles. The Adaptable Human-Machine Interface was developed for hardware-in-the-loop laboratory experiments with a Parrot A.R. Drone 2.0 quadcopter as test case. Based on live video from two on-board cameras, attitude and velocity telemetry, and control inceptor deflection, the interface calculates a predicted flight path and attitude and presents it in a “tunnel in the sky” display. The graphical display itself was developed in the Unity3D game engine. The paper describes the implementation of the interface between Unity3D and the A.R. Drone, the dynamic model of the quadcopter, and the prediction algorithm. The paper also discusses the results of flight tests involving a number of test subjects and projects the path forward in the development of this technology.
Information Behavior of Parents during COVID-19 in Relation to Their Young School-age Children’s Education

This paper explores the information behavior of parents with regard to their young school-age children (PreK and elementary school) during the COVID-19 pandemic, in order to contribute to research ...
Role of substrate temperature at graphene synthesis in an arc discharge

The substrate temperature required for synthesis of graphene in an arc discharge plasma was studied. It was shown that an increase of copper substrate temperature up to the melting point leads to an increase in the amount of graphene production and the quality of graphene sheets. Favorable range of substrate temperatures for arc-based graphene synthesis was determined, and it is in a relatively narrow range of about 1210–1340 K.
Unsupervised in-distribution anomaly detection of new physics through conditional density estimation.

Anomaly detection is a key application of machine learning, but is generally focused on the detection of outlying samples in the low probability density regions of data. Here we instead present and motivate a method for unsupervised in-distribution anomaly detection using a conditional density estimator, designed to find unique, yet completely unknown, sets of samples residing in high probability density regions. We apply this method towards the detection of new physics in simulated Large Hadron Collider (LHC) particle collisions as part of the 2020 LHC Olympics blind challenge, and show how we detected a new particle appearing in only 0.08% of 1 million collision events. The results we present are our original blind submission to the 2020 LHC Olympics, where it achieved the state-of-the-art performance.
A lightweight convolutional neural network for assessing an EEG risk marker for sudden unexpected death in epilepsy.

Convolutional neural network (CNN) has achieved state-of-art performance in many electroencephalogram (EEG) related studies. However, the application of CNN in prediction of risk factors for sudden unexpected death in epilepsy (SUDEP) remains as an underexplored area. It is unclear how the trade-off between computation cost and prediction power varies with changes in the complexity and depth of neural nets. The purpose of this study was to explore the feasibility of using a lightweight CNN to predict SUDEP. A total of 170 patients were included in the analyses. The CNN model was trained using clips with 10-s signals sampled from the original EEG. We implemented Hann function to smooth the raw EEG signal and evaluated its effect by choosing different strength of denoising filter. In addition, we experimented two variations of the proposed model: (1) converting EEG input into an “RGB” format to address EEG channels underlying spatial correlation and (2) incorporating residual network (ResNet) into the bottle neck position of the proposed structure of baseline CNN. The proposed baseline CNN model with lightweight architecture achieved the best AUC of 0.72. A moderate noise removal step facilitated the training of CNN model by ensuring stability of performance. We did not observe further improvement in model’s accuracy by increasing the strength of denoising filter. Post-seizure slow activity in EEG is a potential marker for SUDEP, our proposed lightweight architecture of CNN achieved satisfying trade-off between efficiently identifying such biomarker and computational cost. It also has a flexible interface to be integrated with different variations in structure leaving room for further improvement of the model’s performance in automating EEG signal annotation.
Predictors of Immunoglobulin therapy resistance in Kawasaki disease: Section on Cardiology and Cardiac Surgery Program: Day 2

Purpose: Kawasaki disease (KD) is the most common cause of acquired heart disease in children in developed countries. Timely initiation of treatment with intravenous immunoglobulin (IVIG) has reduced the incidence of coronary artery aneurysms from 25% to 4%. Approximately 10% to 20% of patients with KD are IVIG resistant. Because IVIG-resistant patients are at higher risk for coronary artery aneurysms, it is important to identify these patients who might benefit from more aggressive initial therapy. Currently available IVIG resistance prediction models, originally developed with data from Asian populations, are …
Retrospective Analysis of UNOS Database to Assess the Impact of Induction Therapy on Rejection in Heart Transplantation

Purpose Evidence suggests that routine induction therapy does not improve long-term survival post-heart transplantation. The aim of this study was to evaluate if induction therapy would decrease the risk of treated rejection. Methods A retrospective analysis of 33,922 patients ≥ 18 years old in the UNOS database who underwent heart transplantation 2000-2017 was performed. Patients with prior transplants and dual organ transplants were excluded. The primary end point was treated rejection at one year. Patients were divided into three groups: no induction, induction with IL-2 receptor antagonists (daclizumab and basiliximab) and induction with T-cell depleting agents (alemtuzumab and anti-thymocyte globulins). Results 51% did not receive induction, 25% received IL-2 receptor antagonists and 25% received T-cell depleting agents. Female sex and black race were associated with increased odds of treated rejection at one year (OR 1.321, p Conclusion Induction with T-cell depleting agents reduces the risk of treated rejection at one year. This effect was not seen with IL-2 receptor antagonists. Female sex, higher degrees of HLA mismatch and black race are associated with increased risk of rejection and induction with T-cell depleting antibodies may reduce the risk of treated rejection in this group.
Junglerice (Echinochloa colona) control with sequential applications of glyphosate and clethodim to dicamba

Junglerice is becoming more prevalent in Tennessee, Arkansas, and Mississippi row crop fields. The evolution of glyphosate-resistant (GR) junglerice populations is one reason for the increase. Another possible explanation is that glyphosate and clethodim grass activity is being antagonized by dicamba. This question has led to research to examine whether sequential applications alleviate antagonism observed with dicamba plus glyphosate and/or clethodim mixtures and determine whether sequential treatments with those herbicides at 24 h, 72 h, or 168 h can improve junglerice control. Glyphosate + clethodim applications provided >90% junglerice control. The observed levels of antagonism varied by whether the location of the test was in the greenhouse or the field, and the timing of applications. In the greenhouse, clethodim + dicamba provided excellent control, whereas in the field, the same treatment showed a greater than 30% reduction in junglerice control compared with clethodim alone. However, control was restored by using a mixture of glyphosate + clethodim without dicamba. The environment at the time of application and relative GR level of the junglerice influenced the overall control of these sequential applications. When clethodim applied first followed by dicamba at 72 h or 168 h, better control was observed compared with applying dicamba followed by clethodim. Overall, mixing glyphosate + clethodim provided the most complete junglerice control regardless of timing. These data confirm that leaving dicamba out of the spray tank will mitigate herbicide antagonism on junglerice control. These data would also indicate that avoiding dicamba and glyphosate mixtures will also improve the consistency of control with glyphosate-susceptible junglerice.
Digital cynical romanticism: Japan’s 2channel and the precursors to online extremist cultures

In the West, the concern surrounding the rise of online harassment, trolling and other malicious and antisocial behaviors tend to be hyper focused on websites like 4chan, 8chan and reddit. However,...
Modular, robust and extendible multicellular circuit design in yeast

Abstract Division of labor between cells is ubiquitous in biology but the use of multi-cellular consortia for engineering applications is only beginning to be explored. A significant advantage of multi-cellular circuits is their potential to be modular with respect to composition but this claim has not yet been extensively tested using experiments and quantitative modeling. Here, we construct a library of 24 yeast strains capable of sending, receiving or responding to three molecular signals, characterize them experimentally and build quantitative models of their input-output relationships. We then compose these strains into two- and three-strain cascades as well a four-strain bistable switch and show that experimentally measured consortia dynamics can be predicted from the models of the constituent parts. To further explore the achievable range of behaviors, we perform a fully automated computational search over all two-, three- and four-strain consortia to identify combinations that realize target behaviors including logic gates, band-pass filters and time pulses. Strain combinations that are predicted to map onto a target behavior are further computationally optimized and then experimentally tested. Experiments closely track computational predictions. The high reliability of these model descriptions further strengthens the feasibility and highlights the potential for distributed computing in synthetic biology.
Repetitive Sequences in the Human Genome

Publisher Summary Twenty-five percent of human DNAconsists of repetitive DNA sequences. A general outline of the chromosomal organization of these repetitive sequences is discussed in the chapter. The working hypothesis is that certain classes of human repetitive DNA sequences “encode” the information necessary for defining genomic structure. Using a combination of biochemical, computational, and recombinant DNA approaches, the organization of interspersed, centromeric, and telomeric repetitive DNA in the human genome has been investigated. The distribution of interspersed repeats can be adequately described by models that assume a random spacing, with an average distance of 3 kb. This observed distribution for the integration of interspersed repetitive DNA is the expected result for the sequences that transpose randomly throughout the genome. However, local regions of “preference” or “exclusion” for the integration of repetitive DNA are suggested by the data. Research has isolated three recombinant DNA clones of human repetitive DNA sequences that hybridize specifically to the heterochromatic positions, lqh, 9qh, and 16qh, respectively. These locations were determined by fluorescent in situ hybridization and confirmed by DNA hybridizations to human chromosomes sorted by flow cytometry.
May-Thurner Syndrome

May-Thurner syndrome (MTS) is an anatomic variable condition of venous outflow obstruction, secondary to extrinsic compression. Although this syndrome is rare, its prevalence is likely underestimated. The pathology of this condition is secondary to a partial obstruction of the vein by an overlying artery with subsequent entrapment of the left common iliac vein. Regardless of the mechanism, this causes partial or complete impedance to the iliac vein outflow with subsequent possible obstruction and extensive ipsilateral deep vein thrombosis (DVT) of the ipsilateral extremity. Clinical presentations include, but are not limited to, pain, swelling, venous stasis ulcers, and skin discolorations. With extensive DVT, postphlebitic syndrome – with all of its sequelae – may develop as well. Treatment is based on the clinical presentation. In cases of extensive DVT with MTS, therapy includes staged thrombolysis with prophylactic retrievable inferior vena cava (IVC) filter placement, followed by angioplasty/stenting of the left iliac vein.
Modeling multi-object spatial relationships for satellite image database indexing and retrieval

Geospatial information analysts are interested in spatial configurations of objects in satellite imagery and, more importantly, the ability to search a large-scale database of satellite images using spatial configurations as the query mechanism. In this paper we present a new method to model spatial relationships among sets of three or more objects in satellite images for scene indexing and retrieval by generating discrete spatial signatures. The proposed method is highly insensitive to scaling, rotation, and translation of the spatial configuration. Additionally, the method is efficient for use in real-time applications, such as online satellite image retrievals. Moreover, the number of objects in a spatial configuration has minimal effect on the efficiency of the method.
Data Structures via C++: Objects by Evolution

1. Software Engineering and Computer Programming Software Engineering and Computer Science The Software "Life-Cycle" Why C++? 2. Designing Software: Two Approaches Why Design? Top-Down Design The Object Alternative Which method is Better, TDD or OOD? 3. Software Reliability Riss of Faulty Software Testing Applying Program Correctness Techniques 4. Abstract Data Types, Classes and Objects Problem: Computing with Time Describing Data Types ADT Implementation and Code Reuse Information Hiding, Encapsulation, and Views Creating Encapsulated ADT's Using the C++ Class Using Standard C++ Class Libraries ADT's, Objects, and Object-Oriented Programming 5. Efficiency Selecting Good Algorithms The Many Faces of Program Efficiency Algorithms for Searching Analysis of some Simple Sorting Algorithms 6. Recursion Solving Problems with Recursion Recursive Definitions Applying Recursion to Sorting and Searching Problems How is Recursion implemented? 7. Lists Problem: A Membership Management Program The List ADT Implementing Lists The Inorder List ADT Variations on a Linked List A Dynamic Linear List The Membership Management Program Revisited 8. Stacks Problem: Robot Navigation The Stack ADT Implementing the Stack 1: Array Creating Generic Classes with Templates Implementing the Stack 2: Dynamic List Applications of the Stack ADT The Robot Navigation Problem Solved 9. Queue Problem: Computer Network Performance The Queue ADT Implementing a Queue 1: Array Implementing a Queue 2: Dynamic List Simulation: modelling a computer network 10. Tables A Data Structure to Support Retrieval by Key Implementing a Table Hash Tables for Fast Retrieval Using Tables 11. Trees Introducing Trees Building a Binary Tree Tree Traversal Binary Search Trees Reuse Through Inheritance: A Hierarchy of Trees Performance of Binary Trees 12. Graphs Example: Keeping Track of Course Prerequisites Basic Graph Concepts and Terminology Creating Graph ADT's Implementing and Using Adjacency List Graphs Implementing and Using Adjacency Matrix Graphs Appendix A: A Brief Review of C++ Appendix B: C++ for the Pascal Programmer Appendix C: C++ for the C Programmer
Effect of seat orientation on ingress/egress joint kinematics and reach envelope

BACKGROUND: Little is known about ingress/egress requirements and forward reach for workstations with horizontal seats. This research explored differences between ingress/egress kinematics and reach due to seat orientation. METHODS: 10 participants performed ingress/egress tasks using three seat orientations (horizontal with 90 ◦ and 120 ◦ seat angles, and vertical with 90 ◦ seat angle) and planar reach tasks in three anatomical planes using horizontal and vertical seats with 90 ◦ seat angle. An optical motion capture system was used to record kinematic data. Marker data was processed and modeled to estimate peak joint angles and ranges of motion of several body joints. For reach tasks, marker data of the clavicle and finger were used to plot reach capacity. RESULTS:Ingress/egress joint kinematics differed greatly between horizontal and vertical seats, while few differences existed between the horizontal seat orientations. Peak angles and ranges of motion during ingress/egress of the horizontal seats were significantly higher than the vertical seats, often by a factor of 3–4. The direction of motion affected several peak angles and ranges of motion, but to a lesser extent than seat orientation. Reach was unaffected by seat orientation. CONCLUSION: This study’s findings suggest that ingress/egress of horizontal seats is more stressful for the body, especially the shoulders and lower back, than regular upright seats.
Gödel’s Incompleteness Theorem

In 1931 Kurt Godel [50, 51] proved a momentous theorem with far-reaching philosophical consequences: he showed that no reasonable formal proof sys-tern for number theory can prove all true sentences. This result set the logic community on its ear and left Hilbert’s formalist program in shambles. This result is widely regarded as one of the greatest intellectual achievements of twentieth-century mathematics.
Toward the design of a dashboard to promote environmentally sustainable behavior among office workers

In the United States, over three billion dollars are spent due to office equipment being left on when not in use during the weekend and at night. There is very little incentive for office workers to save energy because utility bills are not directly their responsibility. Our goal is to find ways to reduce the negative impact of this pervasive phenomenon by applying persuasive technologies to create awareness and encourage office workers towards more environmentally sustainable behavior. To this end, we conducted a literature review to investigate the persuasive methods appropriate to the field of building controls. We then proceeded to develop "dashboard-controllers" that enable office workers to control energy-using components with expert feedback to save energy.
Leaving the “Big Deal” … Five Years Later

Southern Illinois University Carbondale (SIUC) and the University of Oregon each withdrew from several Big Deals with major commercial journal publishers from 2008 to 2010. Analysis of the impact of these decisions was originally conducted and reported in 2011 and 2012. This article provides updated analysis based on interlibrary loan statistics, financial savings, and impact on the collections. Results show that interlibrary loan of lost content still represents a small fraction of prior use, savings have been considerable, and the libraries have been able to address other needs in their collections because of the decision to withdraw.
Exercise- and Kefir-induced Internalization of the Anti-inflammatory Melanocortin 3 Receptor in Monocytes

Exercise decreases chronic inflammation and kefir, a fermented milk product, has the potential to further attenuate inflammation. Exercise may upregulate anti-inflammatory pathways in monocytes by ...