cssi/SciSciGPT-SciSciNet huggingface dataset:
Vibrational Spectroscopic and Mass Spectrometric Studies of the Interaction of Bis(3-sulfopropyl)-disulfide with Cu Surfaces

In situ surface enhanced Raman scattering (SERS), infrared-visible sum frequency generation (SFG) spectroscopy, electrospray ionization mass spectrometry (ESI-MS), and detailed calculations are used to examine the interaction of bis(3-sulfopropyl)-disulfide (SPS) and mercaptopropylsulfonic acid (MPS) with Cu surfaces both in the absence and presence of chloride. MPS and SPS SERS spectra are similar to each other, and the lack of a specific S-S feature suggests that SPS interacts with Cu as a thiolate. SERS data show a significant shift in the S-O sulfonate region of the SPS or MPS spectra upon the addition of Cl - , a result which is interpreted as arising from CuCI coordination to the SO 3 moiety of these molecules. CuCl association with SPS is also evidenced in the ESI-MS data. The specific spectral shifts are corroborated by density functional theory calculations. In situ SFG measurements provide evidence that SPS and MPS interact with the Cu surface in solutions not containing Cl - at negative potentials. However, there is no evidence in either the SFG or the SERS for SPS or MPS-Cu coordination in the presence of Cl - at any potential. The data suggest that the thiolate moiety in the additives is not an active component for the acceleration behavior observed.
Measurement of the thermophoretic force by electrodynamic levitation : microspheres in air

Abstract The thermophoretic force on single microspheres has been measured over a wide range of Knudsen numbers and particle thermal conductivities for solid and liquid spheres in air. The microspheres were dioctyl phthalate (DOP) droplets, metallic nickel, polystyrene latex (PSL), and glass. This covers a thermal conductivity ratio (gas to particle) range of 2 × 10−4−0.17. In a companion paper, results are reported for monatomic (helium) and polyatomic gases (carbon dioxide and air) to examine the effects of gas properties. The measurements were accomplished by levitating the particle between heated and cooled plates mounted in a vacuum chamber. Light-scattering phase functions were used to determine the size of all materials except the nickel spheres, and for the highly absorbing metallic spheres the size was obtained by measuring the marginal stability limit of the particle. The apparatus developed for the research and the experimental techniques are discussed, and the experimental results in the Knudsen number range 0.05–20 are compared with previously proposed theories. For particle Knudsen numbers greater than about 10, the effects of the temperature jumps (thermal slip) at the heated and cooled plates become significant. The data in the transition regime overlap Loyalka's (1992, J. Aerosol Sci. 23, 291–300) solution of the linearized Boltzmann equation for hard-sphere molecules, and the data in the slip regime agree with Brock's (1962, J. Colloid Sci. 17, 768–780) theory. The effects of particle thermal conductivity are shown to be nearly negligible in the Knudsen regime, for the data for particles having greatly different thermal conductivities overlap.
Switchable gratings by spatially periodic alignment of liquid crystals via patterned photopolymerization

Spatially periodic patterning of the anchoring condition of a nematic liquid crystal (NLC) within a polymer matrix via a patterned photopolymerization affords a novel and facile method to prepare electrically switchable diffraction gratings. UV irradiation through a photomask of two comonomers, with opposite tendencies to align the NLC and also with different reactivity ratios, leads to definition of areas with either homeotropic or planar alignment of the NLC. Photopolymerization-induced diffusion of the monomers accounts for the spatial distribution of the concentration of these monomers. The resulting diffraction gratings are switchable under low electric fields and possess structural stability offered by the polymer matrix.
The relative contribution of adduct blockage and DNA repair on template utilization during replication of 1,N2-propanodeoxyguanosine and pyrimido[1,2-α]purin-10(3H)-one-adducted M13MB102 genomes

The role of replication blockage by the exocyclic DNA adducts propanodeoxyguanosine (PdG) and pyrimido[1,2-alpha]purin-10(3H)-one (M1G) was determined through the use of site-specifically adducted M13MB102 genomes containing a C:C-mismatch approximately 3000 base-pairs from the site of adduct incorporation. Genomes containing either dG, PdG, or M1G positioned at site 6256 of the (-)-strand were transformed into repair-proficient and repair-deficient Escherichia coli strains and the percent template utilization was determined by hybridization analysis. Unmodified genomes containing a C:C-mismatch resulted in a percent template utilization of approximately 60 and 40% for the (-)- and (+)-strands, respectively. Transformation of PdG- or M(1)G-adducted genomes resulted in approximately a 60-40% and 50-50% (-)-strand to (+)-strand ratio, respectively, indicating that PdG and M(1)G are negligible blocks to replication in repair-proficient E. coli. This is in contrast to previous studies using (PdG:T)- and (M1G:T)-mismatched M13MB102 genomes, which resulted in a majority of the replication events using the unadducted (+)-strand and suggested that both adducts were significant blocks to replication [J. Biol. Chem. 272 (1997) 11434; Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 8652]. The C:C-mismatch results, though, indicate that the large strand bias detected in the earlier studies is due to repair of the adducts and resynthesis of the (-)-strand using the (+)-strand as a template for repair synthesis. Transformation of adducted C:C-mismatched genomes into E. coli strains deficient in nucleotide excision repair did result in an increased strand bias with only approximately 20 and 34% of the replication events using the (-)-strand for PdG- and M1G-adducted genomes, respectively. The increased strand bias indicates the importance of nucleotide excision repair in the removal of PdG and M1G.
Deficient acetyl CoA carboxylase activity in multiple carboxylase deficiency

Multiple carboxylase deficiency has previously been characterized by deficient activity of three biotin-dependent enzymes: propionyl CoA carboxylase, pyruvate carboxylase and beta-methylcrotonyl CoA carboxylase. We have demonstrated that the activity of a fourth carboxylase, acetyl CoA carboxylase (ACC), is also deficient in fibroblasts from two patients with this disorder. Furthermore, ACC activity increased six- to eight-fold when cells from these patients were incubated in culture medium containing supplemental biotin. If the primary defect in multiple carboxylase deficiency is due to deficient activity of holocarboxylase synthetase, our results would indicate that there may be a common holocarboxylase synthetase, or at least a common subunit, for all the carboxylases. Finally, since ACC catalyzes the initial step in fatty acid biosynthesis, our results further suggest the importance of dietary supplementation with fatty acids in addition to treating these patients with pharmacologic doses of biotin.
Does forehead liquid crystal temperature accurately reflect "core" temperature?

Liquid crystal thermometry (LCT) is a non-invasive alternative to temperature monitoring. We evaluated the ability of forehead LCT, rectal temperature, and axillary skin temperature to trend distal oesophageal temperature during rapid warming on cardiopulmonary bypass. In 24 patients undergoing open heart surgery, temperatures were measured during the rapid warming phase on bypass (12–35 min). Scattergrams of temperature vs time for the four temperature sites each contained 150 data points. Polynomial regression analysis revealed that LCT, but not axillary or rectal temperatures, correlated with oesophageal temperature. We conclude that forehead LCT may be useful to monitor temperature trends and to detect rapid elevations in body temperature when more invasive temperature monitoring is inappropriate or unavailable.
Structural luteolysis of induced corpora lutea in "androgen-sterilized" rats.

Five-day-old female rats were made anovulatory by injection of 50 μg testosterone propionate. When the animals were at least 120 days old, corpora lutea (CL) were induced by injection of human chorionic gonadotrophin (HCG). Various treatments were initiated 15 days after HCG and the morphological regression of induced CL was examined 30 days after HCG. Structural luteolysis was very slight in control animals, suggesting that prolactin secretion was minimal. Exogenous prolactin hastened the rate of luteal regression. Daily injections of estradiol or reserpine also caused rapid structural luteolysis. Destruction of the arcuate nucleus of the hypothalamus also induced morphological regression at a more rapid rate than in controls. In conclusion, exogenous prolactin or three different treatments known to promote secretion of endogenous prolactin accelerated the rate of luteal regression in induced CL.
Pavement cracking measurements using 3D laser-scan images

Pavement condition surveying is vital for pavement maintenance programs that ensure ride quality and traffic safety. This paper first introduces an automated pavement inspection system which uses a three-dimensional (3D) camera and a structured laser light to acquire dense transverse profiles of a pavement lane surface when it carries a moving vehicle. After the calibration, the 3D system can yield a depth resolution of 0.5 mm and a transverse resolution of 1.56 mm pixel−1 at 1.4 m camera height from the ground. The scanning rate of the camera can be set to its maximum at 5000 lines s−1, allowing the density of scanned profiles to vary with the vehicle's speed. The paper then illustrates the algorithms that utilize 3D information to detect pavement distress, such as transverse, longitudinal and alligator cracking, and presents the field tests on the system's repeatability when scanning a sample pavement in multiple runs at the same vehicle speed, at different vehicle speeds and under different weather conditions. The results show that this dedicated 3D system can capture accurate pavement images that detail surface distress, and obtain consistent crack measurements in repeated tests and under different driving and lighting conditions.
A new species of Scutellaria (Lamiaceae) from California

Scutellaria holmgreniorum from Lassen Co., California, is described as new. A key to the species ofScutellaria in the Intermountain Region of western United States is provided.
Cellular Automata Investigations of Binary Solidification

A cellular automata model is presented which simulates the process of binary solidification. The experimental system, against which the results are compared, is theNH4Cl?H2Osystem. The model accurately treats the phase-dependent diffusion of solute and can ensure that the growth is truly diffusion-limited. To approximate interface curvature, a template method is employed which incorporates crystalline anisotropy. The model is computationally fast and reproduces the complicated experi-mental structures and dynamics observed at high supersaturations. These include: a stagnation in growth which occurs at a supersaturation corresponding to a crossover in growth rate anisotropy; a jump in dendritic growth velocity at supersaturations greater than this crossover supersaturation; as well as a fine substructure of the stems of these “fast” dendrites. The model also compares well to the analytical moving boundary results available for lower supersaturations.
Differences in intraprocedural ACTs with standardized heparin dosing during catheter ablation for atrial fibrillation in patients treated with dabigatran vs. patients on uninterrupted warfarin

Effective intraprocedural anticoagulation for catheter ablation for atrial fibrillation is critical to minimize the risk of cerebral thromboembolism. The effect of dabigatran on anticoagulation with heparin during the procedure is unknown. This study compares heparin anticoagulation in patients treated with dabigatran vs. patients on uninterrupted warfarin. Seventy-six consecutive patients (24 dabigatran and 52 warfarin) subjected to a standard intraprocedural heparin protocol were included. Heparin administration and rapidity and degree of anticoagulation were compared between the groups. Despite greater administration of heparin (52.5 ± 22.0 vs. 33.2 ± 10.1 units kg−1 h−1; p < 0.001), the mean (320.3 ± 19.5 s) and peak (358.8 ± 28.6 s) activated clotting time (ACT) for the dabigatran group were significantly lower than for the warfarin group (mean, 362.9 ± 35.9 and peak, 410.4 ± 49.7; p < 0.001). The time from initial heparin bolus to first ACT of ≥300 s in the dabigatran group was more than twice that observed in the warfarin group (45.0 ± 30.4 vs. 20.9 ± 14.5 min; p < 0.001). The time to first ACT of ≥350 s was similarly prolonged (109.1 ± 60.0 vs. 55.2 ± 51.1 min; p < 0.001) in the dabigatran group, with eight patients (33 %) failing to reach this target. Outcome differences persisted following analysis using linear models and Cox proportional hazard regression with adjustment for propensity scores. A standard intraprocedural heparin protocol results in delayed and lower levels of anticoagulation as measured by the ACT for patients treated with dabigatran compared with those on uninterrupted warfarin.
Recalling happy memories in remitted depression: A neuroimaging investigation of the repair of sad mood

Major depressive disorder (MDD) is a recurrent mood disorder. The high rate of recurrence of MDD suggests the presence of stable vulnerability factors that place individuals with a history of major depression at an increased risk for the onset of another episode. Previous research has linked the remitted state, and therefore increased vulnerability for depressive relapse, with difficulties in the use of pleasant autobiographical memories to repair sad mood. In the present study, we examined the neural correlates of these difficulties. Groups of 16 currently euthymic, remitted depressed individuals and 16 healthy (control) women underwent functional magnetic resonance imaging (fMRI) during sad mood induction and during recovery from a sad mood state through recall of mood-incongruent positive autobiographical memories. Sad mood was induced in participants by using film clips; participants then recalled positive autobiographical memories, a procedure previously shown to repair negative affect. During both the sad mood induction and automatic mood regulation, control participants exhibited activation in the left ventrolateral prefrontal cortex (vlPFC) and cuneus; in contrast, remitted participants exhibited a decrease in activation in these regions. Furthermore, exploratory analyses revealed that reduced activation levels during mood regulation predicted a worsening of depressive symptoms at a 20-month follow-up assessment. These findings highlight a dynamic role of the vlPFC and cuneus in the experience and modulation of emotional states and suggest that functional anomalies of these brain regions are associated with a history of, and vulnerability to, depression.
Third-Order Nonlinear Optical Properties of Phthalocyanines

This paper discusses the third-order nonlinear optical (NLO) properties of substituted phthalocyanines measured by time-resolved degenerate four-wave mixing at 1064 nm. The study explores optical pumping as a mechanism contributing to a large third-order optical nonlinearity in one member of this interesting class of NLO materials, PbPc(CP) 4 .
Differential expression of cadherins in the developing and adult zebrafish olfactory system

Cadherins are cell adhesion molecules that play important roles in development of a variety of tissues and maintenance of adult structures. Although cadherin expression has been studied in detail in the central nervous system of several vertebrate species, little is known of their distribution in the developing and adult olfactory structures, and there is no published report, to our knowledge, of cadherin expression in fish olfactory system. In this study, we examined expression patterns of three cadherins, cadherin-1 (E-cadherin), cadherin-2 (N-cadherin), and cadherin-4 (R-cadherin), in the olfactory system of developing and adult zebrafish by using both in situ hybridization and immunocytochemical methods. Cadherin-1 is detected in the newly formed olfactory placode, and its expression is maintained in the developing and adult olfactory epithelium and olfactory nerve. Cadherin-2 is expressed in the olfactory epithelium, olfactory nerve, and olfactory bulb of the embryonic and larval zebrafish, and its expression is reduced in the adult olfactory system. In contrast to the cadherin-1 and cadherin-2 expression, cadherin-4 is not found in the olfactory epithelium, but it is detected in the larval and adult olfactory bulb, in the olfactory tract, and its targets in the telencephalon. We hypothesize that the differential expression of these three cadherins in the developing zebrafish major olfactory structures reflects functionally different roles in the development of the vertebrate olfactory system.
337 PRODUCTION OF TRANSGENIC SHEEP USING RECOMBINANT LENTIVIRUS MICROINJECTION OF IN VIVO PRODUCED EMBRYOS

The development of transgenic technology has enormous potential for livestock improvement. Several methods have been employed for generating transgenic livestock to date, the most popular being pronuclear injection or somatic cell nuclear transfer using genetically modified cells. However, the high cost and relatively low efficiencies seen with these methods have prompted development of alternative methods for producing transgenic livestock. Recently, the introduction of transgenes using viral vectors, in particular lentiviral vectors, has provided an avenue for increasing the efficiency of transgenic livestock production. Microinjection of concentrated lentivirus into the perivitelline space of oocytes and zygotes has been demonstrated as an effective means of creating transgenic livestock (cattle, sheep, and swine). In this study, we investigated the efficiency of producing transgenic sheep through microinjection of recombinant lentivirus into in vivo produced zygotes. Recombinant lentivirus was produced through co-transfection of HEK293T cells with various lentiviral transfer plasmids (each coding for a short hairpin RNA and a fluorescent marker protein) as well as a packaging plasmid and a plasmid encoding the vesicular stomatitis virus glycoprotein (VSV-G), which was used to pseudotype viral particles. For lentivirus concentration, a total of 36 mL of viral supernatant was produced per viral construct. Viral supernatant was ultracentrifuged on a 15% sucrose cushion at 4°C for 1.5 h at a speed of 50 000 × g. The resulting viral pellet was resuspended in 30 μL of PBS and virus was frozen at –80°C until needed. Zygotes were surgically flushed from oviducts of superovulated donor ewes 24 h post-mating. Concentrated recombinant lentivirus (titer ≥ IU mL–1) was then microinjected into the perivitelline space. Injected embryos were surgically transferred into the oviduct of synchronized recipient ewes immediately after injection (3–4 embryos per ewe). Pregnancies were confirmed by ultrasound at 35 days of gestation. The pregnancy rate was 39% (45/114 ewes exhibiting at least one viable fetus). A subset of pregnant ewes was killed at 60 to 70 days gestation to harvest a total of 36 fetuses. Analysis of transgene incorporation was performed by PCR using genomic DNA isolated from skin and liver tissue samples. Two independent PCR reactions were performed per sample, and PCR analysis revealed 14 of the collected fetuses to be transgenic (39%). The remaining pregnancies were allowed to progress to term, and 32 lambs were born. Genomic DNA was isolated from blood samples collected on each lamb, and PCR analysis was performed as above. Of the lambs born, 13 of 32 (40%) were confirmed to be transgenic by PCR analysis. Southern blot analysis is currently underway to confirm PCR data. These results demonstrate that microinjection of recombinant lentivirus into in vivo produced sheep zygotes is an effective and efficient method for generating transgenic sheep.
Nkx2-5 Suppresses the Proliferation of Atrial Myocytes and Conduction System

Rationale:Tight control of cardiomyocyte proliferation is essential for the formation of four-chambered heart. Although human mutation of NKX2-5 is linked to septal defects and atrioventricular conduction abnormalities, early lethality and hemodynamic alteration in the mutant models have caused controversy as to whether Nkx2-5 regulates cardiomyocyte proliferation. Objective:In this study, we circumvented these limitations by atrial-restricted deletion of Nkx2-5. Method and Results:Atrial-specific Nkx2-5 mutants died shortly after birth with hyperplastic working myocytes and conduction system including two nodes and internodal tracts. Multicolor reporter analysis revealed that Nkx2-5–null cardiomyocytes displayed clonal proliferative activity throughout the atria, indicating the suppressive role of Nkx2-5 in cardiomyocyte proliferation after chamber ballooning stages. Transcriptome analysis revealed that aberrant activation of Notch signaling underlies hyperproliferation of mutant cardiomyocytes, and forc...
A polyhedral intersection theorem for capacitated spanning trees

In a two-capacitated spanning tree of a complete graph with a distinguished root vertex v, every component of the induced subgraph on V\{v} has at most two vertices. We give a complete, nonredundant characterization of the polytope defined by the convex hull of the incidence vectors of two-capacitated spanning trees. This polytope is the intersection of the spanning tree polytope on the given graph and the matching polytope on the subgraph induced by removing the root node and its incident edges. This result is one of very few known cases in which the intersection of two integer polyhedra yields another integer polyhedron. We also give a complete polyhedral characterization of a related polytope, the 2-capacitated forest polytope.
Newman's conjecture in various settings

Abstract Text De Bruijn and Newman introduced a deformation of the Riemann zeta function ζ ( s ) , and found a real constant Λ which encodes the movement of the zeros of ζ ( s ) under the deformation. The Riemann hypothesis is equivalent to Λ ≤ 0 . Newman conjectured Λ ≥ 0 , remarking “the new conjecture is a quantitative version of the dictum that the Riemann hypothesis, if true, is only barely so.” Previous work could only handle ζ ( s ) and quadratic Dirichlet L-functions, obtaining lower bounds very close to zero ( − 1.14541 ⋅ 10 − 11 for ζ ( s ) and − 1.17 ⋅ 10 − 7 for quadratic Dirichlet L-functions). We generalize to automorphic L-functions and function field L-functions, and explore the limit of these techniques. If D ∈ Z [ T ] is a square-free polynomial of degree 3 and D p the polynomial in F p [ T ] obtained by reducing D modulo p, we prove the Newman constant Λ D p equals log ⁡ | a p ( D ) | 2 p ; by Sato–Tate (if the curve is non-CM) there exists a sequence of primes such that lim n → ∞ ⁡ Λ D p n = 0 . We end by discussing connections with random matrix theory. Video For a video summary of this paper, please visit http://youtu.be/8A1XZtSkp_Q . This author video is a recording of a talk given by Alan Chang at CANT on May 28, 2014.
A sensitivity matched multicarrier modulation

We develop a multicarrier modulation scheme for transmission of compressed data. The energy allocation among subcarriers is optimized by minimizing a modified symbol error function in either AWGN or Rayleigh fading channels. It is observed that our sensitivity matched multicarrier modulation significantly outperforms the conventional multi carrier modulation. The performance gain in Rayleigh fading channels varies from 0.58 to 3.26 dB depending upon the relative sensitivity of bit groups associated with subchannels.
Hostility, Interpersonal Competence, and Daily Dependent Stress: A Daily Model of Stress Generation

We used a daily diary design to evaluate a daily model of stress generation that included both daily sadness and hostility as precipitants, and interpersonal competence as a moderator variable. Our results indicated that daily stress generation was precipitated by daily hostile, but not sad, mood. Participants’ skill at initiating interactions influenced daily stress generation in an unexpected direction. Specifically, the positive daily relationship between hostility and dependent stress was stronger for those with higher initiation scores. The results suggest that stress generation at the daily level functions differently than stress generation involving major life events. We discuss the implications of these findings for future research on stress generation.
Protein structure prediction on the face centered cubic lattice by local search

Ab initio protein structure prediction is an important problem for which several algorithms have been developed. Algorithms differ by how they represent 3D protein conformations (on-lattice, off-lattice, coarse-grain or fine-grain model), by the energy model they consider, and whether they are heuristic or exact algorithms. This paper presents a local search algorithm to find the native state for the Hydrophobic-Polar (HP) model on the Face Centered Cubic (FCC) lattice; i.e. a self-avoiding walk on the FCC lattice with maximum number of H-H contacts. The algorithm relies on a randomized, structured initialization, a novel fitness function to guide the search, and efficient data structures to obtain self-avoiding walks. Experimental results on benchmark instances show the efficiency and excellent performance of our algorithm, and illustrate the biological pertinence of the FCC lattice.
Image quality quantification in camera phone applications

The International Imaging Industry Association (I3A) launched the Camera Phone Image Quality (CPIQ) Initiative in June 2006. The goal of this initiative was to develop an image quality testing and performance rating system that could enable manufacturers and carriers to make comparisons between capture devices, and to communicate a substantiated product quality rating to consumers. The participating companies include wireless network operators, wireless device vendors, camera module manufacturers, camera component manufacturers, and image services providers. This paper will review the image quality issues addressed in the I3A CPIQ effort, the work plan, and the current status of the CPIQ initiative.
Compensatory patterns of sibling support in emerging adulthood: Variations in loneliness, self-esteem, depression and life satisfaction

This study examines how the compensatory effects of social support received from siblings relate to psychological adjustment in emerging adulthood. Participants completed measures of social support from a variety of sources and several indicators of well-being. Sibling support was associated with lower loneliness and depression and with higher self-esteem and life satisfaction. Also, sibling support compensated for low parental and peer support. Sibling support compensated for low support from mothers for depression and self-esteem. Sibling support compensated for low support from fathers for loneliness, self-esteem, and life satisfaction. Finally, sibling support partially compensated for low support from friends for all of the well-being measures and completely compensated for self-esteem, depression, and life satisfaction. The potential benefits of sibling support warrant a closer examination of the wide-ranging issues involved in sibling relations.
Frequency coding of melatonin signals sufficient to induce testicular growth in photoregressed Siberian hamsters.

Integration of melatonin signals over the course of several weeks was studied in male Siberian hamsters maintained in a short day length (10 h light/day) from birth (d 0). On d 35, hamsters with undeveloped testes were housed in constant light and received 5 h s.c. infusions of melatonin (MEL; 100 ng/infusion) or saline (SAL) over the next 30 days. Infusions were provided either every day (30 MEL), every other day (1 MEL/1 OFF), for 2 consecutive days followed by 2 days with no infusion (2 MEL/2 OFF), for 5 consecutive days followed by 5 days with no infusion (5 MEL/5 OFF), for 15 consecutive days followed by 15 days with no infusion (15 MEL/15 OFF), or saline every day (30 SAL). On d 65 testes weights of 30 MEL hamsters were greater than those from 30 SAL, 1 MEL/1 OFF, or 2 MEL/2 OFF groups, but did not differ significantly from those of 5 MEL/5 OFF and 15 MEL/15 OFF animals. Serum FSH concentrations of 30 MEL hamsters exceeded those of all other groups which did not differ among each other. Between 15 and 30 consecutive daily melatonin signals are necessary and sufficient to initiate and sustain maximal gonadotropic activity in juvenile male hamsters kept in constant light. The neuroendocrine system responsive to melatonin does not bridge intervals of more than a day in any of several combinations and apparently is frequency-coded for maximal responsiveness to daily signals.
Woven fabric design and analysis in 3D virtual reality. Part 1: computer aided design and modeling of interlaced structures

A computer model is developed that enables geometric models for woven fabric structures in three dimensions, which would allow engineers to simulate new textile forms in virtual reality and to study the effects of the process parameters on the textile structure. Mathematical models and algorithms for the generation and manipulation of 3D single and multi-layer fabrics are developed.
Simon Peter Meets Simon the Tanner: The Ritual Insignificance of Tanning in Ancient Judaism

Many New Testament exegetes have taken the reference in Acts 9.43 to Peter's stay at Simon the Tanner's house as proof that purity laws are no longer relevant for the author of Acts, since tanning conveys ritual impurity. These interpreters have relied primarily on rabbinic passages to make their argument. This article shows that none of the solicited rabbinic passages refers to tanning as ritually defiling. Rather, the rabbinic sources reveal a disdain for tanners because of their stench and filth. At times, the rabbinic sages also criticize tanners for their supposed lack of moral scruples. Peter's visit to Simon the Tanner's house, therefore, cannot be taken as evidence that the author of Acts dismisses the relevance of the Jewish purity system, let alone kashrut. At best, the reference in Acts to Simon the Tanner informs us about the social-economic status of some of the members of the Jesus movement.
Japan: The Hungry Guest

1. Introduction 2. Nippon Seishin 3. Infinite Variety 4. The Structure of Society 5. The Government of the People 6. Fields, Factories and Workshops 7. Economic Development Up to the World Depression 8. Industrial Recovery and the Invasion of Markets 9. The Condition of the Workers 10. Japan Into Nippon 11. Manifest Destiny 12. Conclusion. Appendix. Glossary. Index.
The Use of AlN Interlayers to Improve GaN Growth on A-Plane Sapphire

The lack of a suitable, lattice matched substrate for the growth of the group III nitrides typically restricts GaN film growth to substrates such as sapphire or SiC, despite the large lattice and thermal mismatch. With the use of AlN or GaN nucleation layers (NL), GaN films of sufficient quality have been produced for blue LEDs. However, for laser and large-area microwave device applications, the large number of dislocations (> 108 cm−2) limit device performance, and techniques are desired to reduce dislocation density during the growth process. Here, we demonstrate how low temperature AlN interlayers (IL) sandwiched between high temperature (HT) GaN layers can be used to improve the electrical, optical, and structural properties of Si doped GaN films. A nearly two-fold increase in mobility is observed in Si doped GaN grown using 5 AlN IL compared to GaN grown on a single AlN NL. For GaN films grown on multiple AlN IL, cross-sectional transmission electron microscopy images reveal a significant reduction in the screw dislocation density and photoluminescence spectra reveal a reduction in yellow band intensity. An analysis of the electrical data based on a single donor/single acceptor model suggests that the improved electron mobility is the result of a reduced acceptor concentration in the top GaN film. The reduction in the calculated acceptor concentration may be associated with the reduction of the screw dislocation density.
Spectrum of weighted composition operators: part 1. Weighted composition operators on C(K) and uniform algebras

The paper contains a complete description of spectrum of disjointness preserving operators on C(K). As an application we fully describe spectrum of weighted automorphisms of unital uniform algebras.
Husband‐wife innovative consumer decision making: Exploring the effect of family power

The study investigates the effect of one component of spousal influence—family power—on the innovative consumer decisions perceived to be made independently by one's mate. Information was gathered via a questionnaire by personally contacting a sample of 71 married couples. The hypothesis tested was that a wife, by virtue of her greater relative exercise of family power, exerts a high degree of influence over the innovative consumer decisions made by her husband. Specifically, it was hypothesized that a wife will have more influence over the choices perceived to be made by her husband than will he. The results supported the hypothesis.
Reproductive cycle of the Namib giant ground gecko, Chondrodactylus angulifer (Squamata: Gekkonidae)

ABSTRACT The reproductive cycle of the Namib giant ground gecko, Chondrodactylus angulifer, from southern Africa was described from a histological examination of gonadal material from museum specimens. Males followed a seasonal testicular cycle in which (based on available specimens) the major period of spermiogenesis occurred between September and December. The onset of spermiogenesis is not known as specimens from May to August were not available. Testes in regression were found in January, February and March. Testes in recrudescence were found in January, February, March and April. Females with enlarged ovarian follicles (>5 mm length) were found in January/February and September to December. Mean clutch size for 36 females was 1.7 ± 0.47 S.D., range: 1–2. Evidence is presented that more than one clutch may be produced in the same reproductive season.
Mechanism for binding of fatty acids to hepatocyte plasma membranes.

The purpose of this study was to examine the interaction between fatty acids and plasma membranes from liver cells. We were unable to reproduce the reported effect of heating on the capacity of these membranes to bind [3H]oleate (Stremmel et al. 1985 Proc. Natl. Acad. Sci. USA. 82: 4-8). In fact, the distribution of [3H]oleate between plasma membranes and unilamellar vesicles of lipids extracted from these membranes was in favor of the lipids, indicating the absence of a detectable amount of binding to a putative fatty acid binding protein in plasma membranes. Radius of curvature of vesicles (125 A vs 475 A) had no effect on the partitioning of fatty acid. In addition, the distribution of [3H]oleate between plasma membranes and other phases had the properties of a partition coefficient over a 200-fold range of [3H]oleate. There was no evidence in this experiment for a binding isotherm, i.e., binding of [3H]oleate at a specific site, superimposed on the nonspecific partitioning of [3H]oleate into the lipids of the plasma membrane. There was no competition between [14C]oleate and [3H]palmitate for entry into plasma membranes. Finally, rates of uptake of [14C]oleate and [3H]palmitate by perfused rat liver were not affected by the presence of the other fatty acid in perfusates. These data indicate that the avidity of hepatocyte plasma membranes for [3H]oleate is a simple consequence of the physical chemical properties of oleate, lipids, and water. The data exclude the idea that the uptake of fatty acids into cells is the result of binding proteins and/or catalyzed reactions at the water-membrane interface of the cell or within the plane of the plasma membrane.
A classification of user tasks in visual analysis of volume data

Empirical findings from studies in one scientific domain have very limited applicability to other domains, unless we formally establish deeper insights on the generalizability of task types. We present a domain-independent classification of visual analysis tasks with volume visualizations. This taxonomy will help researchers design experiments, ensure coverage, and generate hypotheses in empirical studies with volume datasets. To develop our taxonomy, we first interviewed scientists working with spatial data in disparate domains. We then ran a survey to evaluate the design participants in which were scientists and professionals from around the world, working with volume data in various scientific domains. Respondents agreed substantially with our taxonomy design, but also suggested important refinements. We report the results in the form of a goal-based generic categorization of visual analysis tasks with volume visualizations. Our taxonomy covers tasks performed with a wide variety of volume datasets.
Detection of Titanium Silicide Formation and Phase Transformation by Picosecond Ultrasonics

Picosecond ultrasonics is employed to study the titanium silicide formation sequence for evaporated Ti films on silicon substrates annealed at temperatures between 300 and 800 °C. The measurements show significant differences in the ultrasonic echo pattern before and after the structural phases C49 and C54 are formed, thus indicating that picosecond ultrasonics is a sensitive non-destructive probe of silicide formation. The longitudinal sound velocity has been found to be (8.3 ± 0.2) × 10 5 cm/sec for C49 TiSi 2 , and about 5% lower for the C54 phase.
Prey selection and predatory importance of orb-weaving spiders (Araneae: Araneidae, Uloboridae) in Texas cotton

In an unsprayed cotton field in east Texas, orb weavers were one of the numerically dominant groups of spiders, constituting 10% of all spiders collected by D-vac during the summer of 1985 (range, 0.04 individuals/m2 in June to 0.72 individuals/m2 in August). Direct counts, conducted during peak orb-weaver density in August, showed that 0.86 individuals/m2 were found. More than two-thirds of all orb weavers collected by D-vac in cotton consisted of the five species Acanthepeira stellata (Walckenaer), Neoscona arabesca (Walckenaer), Gea heptagon (Hentz), Tetragnatha laboriosa Hentz, and Uloborus glomosus (Walckenaer). Their prey consisted of insects (>99%) and spiders 90% of the prey of the orbweaving spiders, which are characterized as generalist predators. Differences among the five spider species indicate that prey selection was occurring; this seems to be determined by web location, web inclination, and web strength. Of the orb weavers occurring in cotton, 99% were small-sized spiders (primarily G. heptagon ) that intercept small prey with their delicate (about 4 cm diameter) webs. These orb weavers are predators primarily of smallsized pests such as the cotton aphid, Aphis gossypii Glover, and the cotton fleahopper, Pseudatomoscelis seriatus (Reuter).
Calibration of the ATLAS muon spectrometer precision chambers for initial LHC beam collisions

ATLAS is a general purpose experiment at the Large Hadron Collider (LHC) at CERN which began operation in September, 2009. ATLAS has a large muon spectrometer which is designed to measure muon momentum with a resolution ranging from 3% at 100 GeV/c to 10% at 1 TeV for a pseudorapidity range of 0-2.7. In this paper, we describe the derivation and validation of calibration constants for the Monitored Drift Tubes (MDTs) in the ATLAS muon spectrometer for use with initial LHC collisions. At LHC start-up, the luminosity was not sufficient for ordinary calibrations with collision muons, and so alternative methods were developed. The time-to-space (RT) functions were obtained from the University of Michigan gas monitor chamber and the ( t 0 s) were derived from LHC beamsplash events from 2009 and 2010. We have validated these calibration constants by performing muon track reconstruction using 900 GeV collision data from December, 2009 and 7 TeV data from 2010. We find that these calibration constants yield an MDT chamber hit resolution of 142 μ m and a residual width of 91 μ m.
Efficacy and Tolerability of Lacosamide in the Treatment of Children With Refractory Generalized Epilepsy

Lacosamide is FDA-approved in patients 17 years or older with partial-onset epilepsy. We evaluated the efficacy and tolerability of lacosamide in children with refractory generalized epilepsy. We retrospectively reviewed records of 21 children with refractory generalized epilepsy treated with lacosamide in our institution from 2009-2013 divided into 2 subgroups- I, Lennox-Gastaut Syndrome, and II, other generalized epilepsies. Efficacy was defined as seizure freedom or ≥50% seizure reduction. Descriptive data analysis including seizure freedom was compared using c(2) analysis. There were eleven females and ten males with a mean age, of 11.9 years. Five patients became seizure free, nine had ≥50% seizure reduction, and seven had no response. Group I: seven had ≥50% improvement, one did not respond. Group II: five became seizure free, two had ≥50% improvement, five had no response. Lacosamide is effective and well tolerated in children with refractory generalized epilepsy particularly patients with Lennox-Gastaut Syndrome.
Technology Optimization of Tenebriomlitor L. Protein Hydrolyzed by Papain

Objective To optimize the technology condition of Tenebriomlitor L.protein hydrolyzed by papain.Methods With Tenebriomlitor L.as the raw material,the effects of the amount of papain,ratio of solid to liquid,time,temperature and pH value on the extraction efficiency of amino acids were investigated.Results The optimal condition of enzymolysis was as follows: the amount of papain of 2.5%,ratio of solid to liquid of 1:3,hydrolysis for 6 h at 50℃ and pH 6.75.Conclusion The optimal technology condition of Tenebriomlitor L.protein hydrolyzed by papain can be obtained.
Early Side Effects in Treatment of Childhood Cancer

Prevention and treatment of complications are essential to the optimal outcome in the child with a malignant neoplasm. Consideration is given to the toxicity and side effects of therapy and the infectious complications associated with childhood malignancies.
Tongue and Lower Lip Movement in Semivowel /w/ Production.

Aims: Previous studies have shown significant correlations between the acoustic characteristics of /w/ and speech intelligibility. To understand the articulatory pattern in /w/ production, the current study investigated the movement characteristics of the tongue and lower lip in whip productions in comparison to bib productions. Methods: Data from 19 typical adult male participants were collected using electromagnetic articulography. A number of kinematic measures of tongue body (approximately 25 mm posterior to the tongue apex) and lower lip movements were analyzed. Results: The findings suggested different movement patterns of the tongue body and lower lip in whip and bib productions. The amount of lip movement in the anterior-posterior plane exhibited by each speaker did not vary between whip and bib. However, speakers did exhibit more tongue retraction/advancement, greater overall tongue movement, and faster tongue movement speed in whip than in bib. Conclusion: Tongue movement in the anterior-posterior plane, such as tongue retraction and advancement, was found to be crucial for the production of /w/ in typical male speakers. Thus, the articulatory kinematics of the tongue in the anterior-posterior plane and its coordination with the lips need to be further examined in speakers with dysarthria to understand the underlying kinematic characteristics that influence speech intelligibility.
Effects of Differing Instructional Histories on the Resurgence Of Rule-Following

Attempts to explain differences between human and nonhuman sensitivity to changing contingencies have centered around humans’ language ability, and more specifically on instructional control. The present study was conducted to investigate the role of various histories of rule-governance on the resurgence of rule-following during extinction. Results illustrated that specific rule-following histories reduced trials to criterion and enhanced extinction induced resurgence, when compared to general rule-following or no rule-following histories. A concurrent verbal “think-aloud” procedure demonstrated that these results were caused not entirely by experimenter-provided rules, but also by subjects’ generation of self-rules. Implications for the utility of instructional control with human subjects and rule-governance more generally are discussed.
The role of break-induced replication in large-scale expansions of (CAG)n/(CTG)n repeats

A newly developed assay in yeast reveals that large-scale expansions of trinucleotide repeats can occur in a single step, rather than through several small-scale events. Expansions of (CAG)n/(CTG)n trinucleotide repeats are responsible for over a dozen neuromuscular and neurodegenerative disorders. Large-scale expansions are commonly observed in human pedigrees and may be explained by iterative small-scale events such as strand slippage during replication or repair DNA synthesis. Alternatively, a distinct mechanism may lead to a large-scale repeat expansion as a single step. To distinguish between these possibilities, we developed a novel experimental system specifically tuned to analyze large-scale expansions of (CAG)n/(CTG)n repeats in Saccharomyces cerevisiae. The median size of repeat expansions was ∼60 triplets, although we also observed additions of more than 150 triplets. Genetic analysis revealed that Rad51, Rad52, Mre11, Pol32, Pif1, and Mus81 and/or Yen1 proteins are required for large-scale expansions, whereas proteins previously implicated in small-scale expansions are not involved. From these results, we propose a new model for large-scale expansions, which is based on the recovery of replication forks broken at (CAG)n/(CTG)n repeats via break-induced replication.
Speculative blackness: the future of race in science fiction

The author commences with his discourse by stating that (this volume) assays the notion that race is socially constructed, its meaning shaped by the habits of persons and institutions; by scrutiniz...