cssi/SciSciGPT-SciSciNet huggingface dataset:
Rough querying: a real-world information systems project

This paper discusses the development and implementation of a rough relational database system by students in a junior level information systems course. Team work skills as well as software engineering life cycle models are emphasized throughout the course. Students learn vital software engineering skills while developing a real world system that incorporates rough set uncertainty management in the querying of data.
Nest mate size, but not short-term need, influences begging behavior of a generalist brood parasite

Hosts of generalist brood parasites often vary with regards to their life-history traits, and these differences have the potential to influence the competitive environment experienced by brood-parasitic nestlings. Although begging by brood parasites is more exaggerated than their hosts, it is unclear if generalist brood parasites modulate their begging behavior relative to host size. I examined the begging behavior of brown-headed cowbird (Molothrus ater) nestlings when competing against nest mates that differ in size and under different levels of short-term need. Cowbird nestlings begged on nearly all feeding visits, responded to adults as fast as (or faster than) their nest mates, and typically begged more intensively than their nest mates. Latency to beg, time spent begging, and maximum begging posture of cowbirds were similar during supplementation and deprivation treatments, indicating begging intensity was not influenced by short-term need. Time spent begging by cowbirds varied among hosts of 3 different sizes when short-term need was standardized, suggesting that nest mate size strongly influenced begging behavior. Cowbirds obtained more food when competing against an intermediate-sized host due to lower provisioning rates of small hosts or because of increased competitive ability of large host nestlings. Overall, cowbirds obtained the greatest volume of food per unit time spent begging when competing against intermediate hosts, but this value approached that of the small host when adjusted for modal brood size. These results demonstrate that cowbirds adjust their begging relative to the size of the hosts against which they compete but not to levels of short-term need. Key words: begging behavior, begging intensity, brown-headed cowbird, Molothrus ater, nestling competition, short-term need. [Behav Ecol]
Ambient Noise Levels in Industrial Audiometric Test Rooms

In 1983 the Occupational Safety and Health Administration (OSHA) specified maximum permissible ambient noise levels (MPANLs) that would allow valid hearing threshold measurements in an audiometric test room. However, ambient noise sound pressure levels (SPLs) in rooms used for industrial hearing tests are unknown. The present study reports octave band (125 to 8000 Hz) ambient noise SPLs measured in 490 single-walled prefabricated audiometric test rooms located in industrial settings that were obtained from eight sources. The ambient noise SPLs were highest in the lower frequencies and decreased as frequency increased. All 490 rooms met the OSHA MPANLs. Fortunately, the ambient noise SPLs were considerably lower than the OSHA MPANLs, since previous research has demonstrated that hearing thresholds cannot be obtained down to 0-dB HL in a test room having ambient noise levels equal to the OSHA MPANLs. In fact, 33%, or 162 of the 490 test rooms, met the more stringent MPANLs recently specified by the American National Standards Institute (ANSI) for industrial hearing testing. Given that the OSHA MPANLs are too high and that the test room ambient noise SPLs were considerably less than the OSHA MPANLs, that authors recommend that the OSHA MPANLs be revised to the more stringent ANSI 1991 MPANLs so that hearing thresholds for baseline and annual audiograms can be measured down to 0-dB HL.
Certain fractional q-integrals and q-derivatives

In a recent paper Al-Salam(1) has denned a fractional q-integral operator by the basic integral(1) Where α ≠ 0, −1, −2, …. Using the series definition of the basic integrals, (1·1) is written asvalid for all α
The antiferromagnetism of uranium monophosphide

Abstract Uranium monophosphide crystallizes in a NaCl-type structure with a 0 = 5.590 ± 0.004 A. It is paramagnetic at room temperature and antiferromagnetic at liquid nitrogen temperature. The chemical and magnetic unit cells are of the same size. The magnetic moment directions and the positions of the 4 uranium atoms in the magnetic cell are, +: 0 0 0; 1/2 1/2 0 and −: 1/2 0 1/2; 0 1/2 1/2. They are aligned ferromagnetically in each layer but oppositely aligned in alternating layers perpendicular to (001) plane. The symmetry of the chemical cell is cubic but of the magnetic cell tetragonal. The atomic magnetic moment at liquid nitrogen temperature is 1.72 ± 0.02 Bohr magnetons. A magnetic form-factor curve for the uranium atoms is given.
An economical and effective high‐throughput DNA extraction protocol for molecular marker analysis in honeybees

The honeybee is becoming an increasingly important organism in the realm of laboratory-based genetics. As honey bee health around the world is declining, measures are being taken to understand the genetic basis of a multitude of traits including behavior, disease resistance, survivability, honey production, and pollination efficiency. Quantitative Trait Loci (QTL) studies and mapping projects are elucidating the complex interactions of genetic loci that dictate the important traits being bred for by beekeepers, queen producers, and researchers alike. Quantitative Trait Loci for foraging behavior and aggression were identified nearly 15 years ago (Hunt et al., 1995, 1998), long before the advancements of the current and ongoing honey bee genome project (Honey Bee Genome Sequencing Consortium, Baylor College of Medicine, Houston, TX, USA). More recent studies have identified a single QTL for chalkbrood disease resistance (Holloway et al., 2012) and have utilized the genome data to finemap the interval to contain just two genes of potential interest (Holloway et al., 2013). As QTL studies are becoming more commonplace in the understanding of honey bee genetics, DNA extractionmethods are needing to be faster, more effective, andmore economical to keep pace with the analyses of the populations being studied. Honey bee QTL studies are generating information on potential gene or allele functionality relevant to mapping populations. Yet, narrowing the intervals and pinpointing the genes of interest for eventual marker-assisted selection requires hundreds or even thousands of phenotyped bees to be processed for DNA extraction and genotyping. Typically, the extraction processes yield good qualities and quantities of DNA per individual sample, yet are costly in time and materials. Commercial DNA extraction kits allow for consistent and reproducible yields, yet can cost several dollars per sample. Chelating agents purify DNA with high quality but may require long incubations and preparations with additional proteinase K (Giraffa et al., 2000; Casquet et al., 2012). Traditional phenol-chloroform extractions require handling, storage, and disposal of hazardous organic solvents. Honey bee DNA has recently been effectively extracted and purified by homogenization and utilizing proteinase K and ‘salting-out’ methods to remove proteins (Bourgeois et al., 2008, 2010; Bourgeois & Rinderer, 2009). However, we developed a simple, costeffective, and fast method using only sodium chloride and sodiumdodecylsulfate (SDS) to extract clean DNAdirectly useable for PCR without additional dilution as is typically required. This method is particularly useful for highthroughput extraction of DNA from large numbers of individual bees while minimizing labor, plastic consumables, and reagent requirements. The resulting DNA is of a high enough quality and quantity to directly amplify bands for molecular marker analysis.
Movement Characteristics of Hamster and Guinea Pig Spermatozoa upon Attachment to the Zona Pellucida

Movement characteristics of hamster and guinea pig spermatozoa were studied by high-speed cinemicrography before and after initial binding to the zona pellucida. Hamster spermatozoa that had previously undergone motility activation in vivo or in vitro maintained vigorous behavior upon zona attachment. They continued to propagate flagellar waves of large amplitude and curvature, although these waves were much more symmetrical than when prior to zona attachment. The hamster sperm activated in vitro appeared slightly stimulated upon zona attachment. Such spermatozoa also bound to the zonae pellucidae of mouse eggs, and they exhibited similar movements. Preactivated hamster spermatozoa, fresh from the epididymis, did attach to the hamster zona, but exhibited relatively weak flagellar beats of low amplitude and frequency. Guinea pig spermatozoa, activated in vitro, also continued such movement and appeared somewhat stimulated upon attachment to the zona pellucida of their species.
PhCHP(MeNCH2CH2)3N: A novel ylide in the Wittig reaction

Abstract The title semi-stabilized ylide prepared from the commercially available non-ionic superbase P(MeNCH2CH2)3N reacts with aldehydes to give alkenes in high yield with surprisingly quantitative E selectivity.
Undergraduate Geography Students Define Aesthetic Maps

Several aesthetic map definition approaches aim to describe the components, concepts and aspects of aesthetic maps. While the discussion is mostly conducted by mapping professionals and researchers, one may wonder how naive map users would define an aesthetic map. Thirty-four undergraduate geography students answered a short questionnaire in which they defined an aesthetic map, and identified the most aesthetic map along with the reasons why they liked that particular map. Preliminary findings indicate that two important concepts for aesthetic maps are clarity and being visually pleasing/attractive. Favorite aesthetic maps ranged widely from reference to thematic to imaginary maps. Questionnaire results also indicate the emerging importance of and possible aesthetic paradigm shift towards mobile and other interactive, web-based spatial representations. Naive aesthetic map definitions could provide an important insight into current and future aesthetic map trends.
Learning appearance manifolds from video

The appearance of dynamic scenes is often largely governed by a latent low-dimensional dynamic process. We show how to learn a mapping from video frames to this low-dimensional representation by exploiting the temporal coherence between frames and supervision from a user. This function maps the frames of the video to a low-dimensional sequence that evolves according to Markovian dynamics. This ensures that the recovered low-dimensional sequence represents a physically meaningful process. We relate our algorithm to manifold learning, semi-supervised learning, and system identification, and demonstrate it on the tasks of tracking 3D rigid objects, deformable bodies, and articulated bodies. We also show how to use the inverse of this mapping to manipulate video.
Development of Complement-Fixing 19S, Anti-Heart Mitochondria Autoantibody, Following Myocardial Infarction in Dogs

The development of anti-heart autoantibody following experimental myocardial infarction in dogs was studied with respect to (1) the subcellular localization of the heart autoantigen(s), (2) the incidence of autoantibody following myocardial infarction, and (3) the temporal development of the autoantibody and its relation to serum enzyme elevations and electrocardiographic changes. Complement-fixing anti-heart autoantibody developed following myocardial infarction induced by either two-stage coronary artery ligation or by the injection of microspheres directly into the coronary circulation. The autoantibody was directed toward an autoantigen residing in the mitochondrial fraction of myocardial tissue and was found to be associated with the 19S class of immunoglobulin. Eighteen of 20 dogs with infarction produced anti-heart mitochondria autoantibody 10 days following induction of myocardial damage; the autoantibody persisted 4 to 6 weeks thereafter. In these dogs the presence of anti-heart mitochondria auto...
Prediction of Composition of Anomalous Cryptoperthites from the Rattlesnake Mountain Sill, West Texas, Using Stepwise Multiple Linear Regression Techniques

Unit-cell refinements of the K-rich phase of some strongly anomalous cryptoperthites from the Rattlesnake Mountain sill, West Texas, have been obtained. Compositions of the K-rich phases were estimated from the unit-cell volume, and bulk compositions were estimated from measured d(201)s of the homogenized phases. Stepwise multiple linear regression analysis was selected to examine the relation between selected measured parameters and the unit-cell volume of the K-rich phase and d(201) of the homogenized phase. Variables that add significantly to the prediction of the unit-cell volume are sensitive to the composition and distortion of the K-rich phase, and those that predict d(201) are sensitive to the estimated order of the K-rich phase and the distortion of the K-rich phase.
Visual/Acoustic Emotion Recognition

To recognize and understand a person's emotion has been known as one of the most important issue in human-computer interaction. In this paper, we present a multimodal system that supports emotion recognition from both visual and acoustic feature analysis. Our main achievement is that with this bimodal method, we can effectively extend the recognized emotion categories compared to when only visual or acoustic feature analysis works alone. We also show that by carefully cooperating bimodal features, the recognition precision of each emotion category will exceed the limit set up by the single modality, both visual and acoustic. Moreover, we believe our system is closer to real human perception and experience and hence will make emotion recognition closer to practical application in the future
THERMAL INCREMENTS FOR PULSATION-FREQUENCY IN "ACCESSORY HEARTS" OF NOTONECTA.

The frequencies of pulsation of the "accessory hearts" in the isolated swimming-legs of Notonecta were studied in relation to temperature, with the idea that in such organs central nervous control is impossible, and that in an isolated system irreversibly proceeding toward death it might be expected that further evidence would be found regarding the supposed specific significance of critical thermal increments. A number of values of µ are found, commonly 8,200; 16,200; or 32,200; less frequently 11,400; 19,800; and 24,500. These values are definitely contrasted with that (12,300) typical for heart beat frequencies in arthropods. They exhibit interrelationships of the sorts already found in other cases. There occur also sharp irreversible changes in frequency of pulsation, which may or may not be accompanied by change of increment. The net result is held to be confirmatory of the interpretation of thermal relations proposed in earlier papers.
Virtual Screening of Combinatorial Libraries across a Gene Family: in Search of Inhibitors of Giardia lamblia Guanine Phosphoribosyltransferase

Parasitic protozoa lack the ability to synthesize purine nucleotides de novo, relying instead on purine salvage enzymes for their survival. Guanine phosphoribosyltransferase (GPRT) from the protozoan parasite Giardia lamblia is a potential target for rational antiparasitic drug design, based on the experimental evidence, which indicates the lack of interconversion between adenine and guanine nucleotide pools. The present study is a continuation of our efforts to use three-dimensional structures of parasitic phosphoribosyltransferases (PRTs) to design novel antiparasitic agents. Two micromolar phthalimide-based GPRT inhibitors were identified by screening the in-house phthalimide library. A combination of structure-based scaffold selection using virtual library screening across the PRT gene family and solid phase library synthesis led to identification of smaller (molecular weight, K i values in the 23 to 25 μM range. These results represent significant progress toward the goal of designing potent inhibitors of purine salvage in Giardia parasites. As a second step in this process, altering the phthalimide moiety to optimize interactions in the guanine-binding pocket of GPRT is expected to lead to compounds with promising activity against G. lamblia PRT.
Finding four-node subgraphs in triangle time

We present new algorithms for finding induced four-node subgraphs in a given graph, which run in time roughly that of detecting a clique on three nodes (i.e., a triangle).• The best known algorithms for triangle finding in an n-node graph take O(nω) time, where ω
Nutrition Management of the Critically Ill Pediatric Patient Minimizing Barriers to Optimal Nutrition Support

Provision of optimal nutritional support to children in the pediatric intensive care unit (PICU) is important for optimizing nutritional management, yet challenging because of a variety of factors....
Determination of the content of mercury and analysis of the influencing factors on the dissolution of cinnabar in digestive juice

OBJECTIVE To determine the content of mercury in different speciation and analysis the of influencing factors on the dissolution of cinnabar in digestive juice.METHODS The content of total mercury in various dissolution of cinnabar were analyzed by Chemical digestion method-AAS method.The effects of different chemical factors in gastrointestinal tract,i.e.pH,pepsin,ionicstrength,Na2S,So,Na+、K+ on the dissolution speciation of cinnabar were investigated.RESULTS The solubility of cinnabar could be increased significantly in the presence of Na2S/So,and strong acidic pH,respectively.While Na+,K+,pepsin had relatively low influence on the dissolution of cinnabar in artificial intestinal juice.CONCLUSION The dissolution of cinnabar in digestive juice(inorganic,organic,ion state)have a close relationship with HgS contents,pH and sulfide.
Fault diagnosis of rolling bearings based on an improved time-varying autoregressive model

An improved time-varying autoregressive model was established for rolling bearing fault diagnosis based on combination of forward and backward estimation.By adopting time-varying forgetting factor,mean squared error based on forward and backward estimation was defined and partial derivatives were derived for weighted coefficients of basis functions to obtain their calculation formulas.Then,the recursion formulas of the weighted coefficients were derived using recursive least squares(RLS).Time-frequency analysis for simulation and experimental signals of a faulty bearing inner ring was conducted using the improved and unimproved models.The results showed that the improved model can overcome the unavailability of frequency estimation at the initial time,it has higher accuracy in temporal and frequency estimation, and better anti-noise performance;so the improved model can extract fault feature frequency of rolling bearing more effectively.
Runoff-yield model based on statistical theory

Based on statistical theory,a runoff-yield model,considering the spatial variations of rainfall,soil infiltration capacity and water storage capacity,is proposed in this paper. It is supposed that the spatial variations of a rainfall event could be described using a Probability Density Function(PDF) or a Cumulative Distribution Function(CDF),and the specific PDF or CDF at every time step of the rainfall event is estimated by adopting the goodness-of-fit approach to match the curve with the real rainfall data. The parabolic types of mathematical functions are used to represent the spatial distributions of soil infiltration capacity and water storage capacity. According to the joint probability distribution of rainfall and soil infiltration capacity,the distribution of surface runoff is deduced from the infiltration excess mechanism,and the further analytical solution to surface runoff is obtained. Infiltration supplements soil moisture,and when infiltration reaches the field capacity,it yields the groundwater flow which is calculated with the amounts of infiltration and the distribution of the water storage capacity. For instance,the proposed model is applied to Dongwan Basin,a semi-humid region located at the middle reach of Yellow River. Results are also compared with those obtained by the Xinanjiang model. It turns out that the statistically-based runoff-yield model could achieve the promising results with acceptable accuracy for flood events' simulation and forecast.
Assessing the subjective effects of stimulants in casual users; A methodology and preliminary results

In order to assess the subjective effects of nefopam, a new non-opiate analgesic, a study was designed using highly educated, young, middle-to-upper class subjects in a naturalistic setting. Results suggest that the design is capable of differentiating variations in subjective drug effects. On a number of measures, 10 mg of d-amphetamine, a modest dosage, could be distinguished from placebo, showing changes in the direction expected for stimulant drugs. Nefopam (90 mg), on the other hand, showed few differences from placebo or caffeine (300 mg). Nefopam appeared mildly dysphoric, rather than stimulant, in subjective effects.
Institutional characteristics and the connection to college student health.

OBJECTIVE To examine whether 6 institutional characteristics were associated with health behavior and outcomes among college students. METHODS Chisquare statistics and ANOVAs were used to determine relationships between institutional characteristics and health issues among undergraduate participants (N = 81,242) for the spring 2011 American College Health Association-National College Health Assessment II. RESULTS Most institutional characteristics were significantly associated with all health issues. However, Cramer's V and eta 2 were frequently weak. Relationships between institutional characteristics and health outcomes were complex with few clear patterns. CONCLUSIONS This exploratory study provides insight into environmental influences specific to college health. Future research should consider individual student differences and campus offerings to improve understanding of how the environment affects college student health.
Prostate size, nocturia and the digital rectal examination: a cohort study of 30 500 men.

Objectives To evaluate the utility of the digital rectal examination (DRE) in estimating prostate size and the association of DRE with nocturia in a population-based cohort. Subjects and Methods We identified all men randomized to the screening arm of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening (PLCO) trial for whom DRE results were available. Men were excluded if they had a history of prostate surgery or incident prostate cancer. Prostate posterior surface area was derived from DRE sagittal and transverse estimates. Relationships between prostate posterior surface area, transrectal ultrasonography (TRUS), prostate-specific antigen (PSA) and nocturia were analysed using intraclass correlation coefficients (ICCs), Spearman's rank correlation and multivariable logistic regression. Results A total of 30 500 men met the inclusion criteria, with 103 275 screening visits containing paired DRE and PSA data. Digital rectal examination posterior surface area estimates had an ICC of 0.547 (95% CI 0.541–0.554) and were significantly yet modestly correlated with elevated PSA level (rs = 0.18, P < 0.001) and TRUS prostate volume (rs = 0.32, P < 0.001). Prostate posterior surface area was significantly associated with nocturia on multivariable analysis, but was not significant in stratified analysis of men with cardiovascular risk factors (hypertension, diabetes, high body mass index, stroke). In men without these risk factors, the highest quintile of DRE posterior surface area had 22% greater odds of nocturia than the lowest quintile (odds ratio 1.216, 95% CI 1.036–1.427). Conclusions Digital rectal examination is a modestly accurate tool for measuring prostate volume. While DRE posterior surface area represents a statistically significant predictor of nocturia, the magnitude of effect suggests it has limited clinical utility for assessing this condition, particularly in the presence of cardiovascular risk factors.
Fundamentals of Lightning

This new book provides a focused set of topics suitable for advanced undergraduate or graduate courses on lightning. It presents the current state of the art in lightning science including areas such as lightning modeling, calculation of lightning electromagnetic fields, electromagnetic methods of lightning location, and lightning damaging effects and protective techniques. Pedagogical features designed to facilitate class learning include end-of-chapter summaries, further reading suggestions, questions and problems, and a glossary explaining key lightning and atmospheric electricity terms. A selection of appendices are provided at the end of the book, which include detailed derivations of exact equations for computing electric and magnetic fields produced by lightning. Designed for a single-semester course on lightning and its effects, and written in a style accessible to technical non-experts, this book will also be a useful, up-to-date reference for scientists, engineers and practitioners who have to deal with lightning in their work.
Cancer risk in cutaneous lupus erythematosus: a population-based cohort study.

Objective Immune dysregulation associated with chronic autoimmune diseases, such as SLE, has been associated with increased cancer risk. It is unclear whether isolated cutaneous lupus erythematosus (CLE) modifies cancer risk. We estimated the cumulative incidence of cancer in a population-based CLE cohort and compared the risk with a matched non-CLE cohort. Methods All incident cases of CLE in Olmsted County, MN, USA between 1965 and 2005 were identified and followed to December 2013. Estimates for the cumulative incidence of any cancer and skin cancer in patients with CLE were derived and compared with an age-, sex- and calendar-year-matched non-CLE cohort using Cox models. Results There were a total of 155 patients with CLE [age at diagnosis, 48 (sd 16) years; 65% females; BMI, 26.3 (sd 7.1) kg/m2; 40% smokers, 9% with diabetes]. During a median follow-up of 14.6 years, we observed 35 cases of incident cancer (including 10 cases of skin cancer). The cumulative 1-, 5- and 10-year incidence of any cancer after diagnosis of CLE was 1.4, 7.5 and 11.6%, respectively. Compared with matched non-CLE controls, the overall risk of malignancies was not increased in patients with CLE (smoking-adjusted hazard ratio = 1.29; 95% CI: 0.78, 2.13; P = 0.31). There was also no significant increase in risk of any skin cancer in patients with CLE (hazard ratio = 2.51; 95% CI: 0.91, 6.96; P = 0.16). Conclusion CLE is not associated with an increased risk of any cancers, including skin cancers, compared with the general population. However, the number of events was small, limiting the power of the study.
African Christian Approaches to Other Religions

This chapter explores African Christian approaches to other religions. Informing that African Christians have been coming together in search of an African and Christian approach to interfaith relations, the chapter discusses their efforts in view of identifying key elements in African spirituality pertinent to harmonious and life-giving relationships. It begins by mapping out the religious terrain in the different regions of Africa, highlighting how the history and context shape interfaith relations. It then offers an overview of Christian approaches to other religions and spells out significant features that characterize African theology. Its thesis is that life, unity, interdependence, simplicity, and togetherness are essential ingredients to facilitating holistic interfaith relations.
The Delivery of Accounting in the Problem-Based Learning Environment

The full-time, residential MBA program at Ohio University is delivered using a problem-based learning (PBL) pedagogy. This article addresses the delivery of the targeted accounting competencies in that program. The principles and techniques outlined herein are also being used, on a modified basis, to deliver an elementary accounting course in the undergraduate program.
Risk assessment of the blunt trauma victim: The role of the quick Sequential Organ Failure Assessment Score (qSOFA).

Abstract Background A number or risk assessment tools are used in trauma victims. Because of its simplicity, we examined the ability of the recently described quick Sequential Organ Failure Assessment Score (qSOFA) to predict outcomes in blunt trauma patients presenting to the Emergency Department. Methods We queried the trauma registry at a Level 1 Trauma Center for all adult blunt trauma admissions between 1/1/10 and 9/30/15. qSOFA scores were the sum of binary scores for 3 variables (RR ≥ 22, SBP≤100 mmHg, and GCS≤13). Results There were 7064 admissions (5664 admissions had qSOFA = 0, 1164 had qSOFA = 1, 223 had qSOFA = 2, and 13 had qSOFA = 3). Higher qSOFA scores were associated with greater injury severity, increased ICU admission, and higher complication rates. qSOFA scores were associated with in-hospital mortality (1.7% with qSOFA = 0; 8.7% with qSOFA = 1; 22.4% with qSOFA = 2; 23.1% with qSOFA = 3; p Conclusions qSOFA scores are directly associated with adverse outcomes in blunt trauma victims.
A New Proactive Scheduling Methodology for Front-End Crude Oil and Refinery Operations under Uncertainty of Shipping Delay

Crude oil planning and scheduling is crucial to petroleum refineries because of the potential for significant economic benefits. In reality, however, crude oil scheduling activities are highly vulnerable to disruptions caused by various uncertainties. In this paper, a new proactive scheduling methodology simultaneously covering crude unloading, transferring, and processing (CUTP) has been developed. The CUTP scheduling methodology is to maximize the total profit subject to various inventory, operation, transportation, and production constraints, while maintaining the refinery normal operating conditions under the uncertainty of crude shipping delays. To quantify shipping delay uncertainties, a combined feasibility index has been developed and embedded into the developed continuous-time mixed-integer nonlinear programming scheduling model, which is solved by the global solver of ANTIGONE. In addition, the relationship between the total profit and the minimum flexibility threshold is also given. The efficac...
Design of spectral-spatial phase prewinding pulses and their use in small-tip fast recovery steady-state imaging.

PURPOSE Spectrally selective "prewinding" radiofrequency pulses can counteract B0 inhomogeneity in steady-state sequences, but can only prephase a limited range of off-resonance. We propose spectral-spatial small-tip angle prewinding pulses that increase the off-resonance bandwidth that can be successfully prephased by incorporating spatially tailored excitation patterns. THEORY AND METHODS We present a feasibility study to compare spectral and spectral-spatial prewinding pulses. These pulses add a prephasing term to the target magnetization pattern that aims to recover an assigned off-resonance bandwidth at the echo time. For spectral-spatial pulses, the design bandwidth is centered at the off-resonance frequency for each spatial location in a field map. We use these pulses in the small-tip fast recovery steady-state sequence, which is similar to balanced steady-state free precession. We investigate improvement of spectral-spatial pulses over spectral pulses using simulations and small-tip fast recovery scans of a gel phantom and human brain. RESULTS In simulation, spectral-spatial pulses yielded lower normalized root mean squared excitation error than spectral pulses. For both experiments, the spectral-spatial pulse images are also qualitatively better (more uniform, less signal loss) than the spectral pulse images. CONCLUSION Spectral-spatial prewinding pulses can prephase over a larger range of off-resonance than their purely spectral counterparts. Magn Reson Med 79:1377-1386, 2018. © 2017 International Society for Magnetic Resonance in Medicine.
Breakpoints and Concurrent Factors

Up to this point, we have articulated a synthesized model of organizational change, and we subsequently detailed some initial findings about the moments at which the organizational configuration of Wikipedia—or the manner in which that configuration was changing over time—shifted. In this chapter, we analyze the revisions made to key Wikipedia policy pages as well as contributions made to their associated “Talk” pages, in which editors discuss the revisions being made, in addition to larger societal events that may have affected Wikipedia. The findings of this archival search are used to assess the significant internal and external motors that acted upon the Wikipedia collaborative community to foster these configurational changes.
Semi‐Parametric Estimation for Non‐Gaussian Non‐Minimum Phase ARMA Models

We consider inference for the parameters of general autoregressive moving average (ARMA) models which are possibly non-causal/non-invertible (also referred to as non-minimum phase) and driven by a non-Gaussian distribution. For non-minimum phase models, the observations can depend on both the past and future shocks in the system. The non-Gaussianity constraint is necessary to distinguish between causal-invertible and non-causal/non-invertible models. Many of the existing estimation procedures adopt quasi-likelihood methods by assuming a non-Gaussian density function for the noise distribution that is fully known up to a scalar parameter. To relax such distributional restrictions, we borrow ideas from non-parametric density estimation and propose a semi-parametric maximum likelihood estimation procedure, in which the noise distribution is projected onto the space of log-concave measures. We show the maximum likelihood estimators (MLEs) in this semi-parametric setting are consistent. In fact, the MLE is robust to the misspecification of log-concavity in cases where the true distribution of the noise is close to its log-concave projection (Cule and Samworth, 2010; Dumbgen et al., 2011). We derive a lower bound for the best asymptotic variance of regular estimators at rate n−12 for autoregressive (AR) models and construct a semi-parametric efficient one-step estimator. The estimation procedure is illustrated via a simulation study and an empirical example illustrating the methodology is also provided.
Catalytic Asymmetric Synthesis of Trifluoromethylated γ-Amino Acids through the Umpolung Addition of Trifluoromethyl Imines to Carboxylic Acid Derivatives.

Novel cinchona alkaloid derived chiral phase-transfer catalysts enabled the highly chemo-, regio-, diastereo-, and enantioselective umpolung addition of trifluoromethyl imines to α,β-unsaturated N-acyl pyrroles. With a catalyst loading ranging from 0.2 to 5.0 mol %, this new catalytic asymmetric transformation provides facile and high-yielding access to highly enantiomerically enriched chiral trifluoromethylated γ-amino acids and γ-lactams.
Molecular dynamics study of lubricant depletion by pulsed laser heating

Abstract In this study, molecular dynamics simulations were performed to numerically investigate the effect of pulsed laser heating on lubricant depletion. The maximum temperature, the lubricant depletion width, the number of evaporated lubricant beads and the number of fragmented lubricant chains were studied as a function of laser peak power, pulse duration and repetition rate. A continuous-wave laser and a square pulse laser were simulated and compared to a Gaussian pulse laser. With increasing repetition rate, pulsed laser heating was found to approach continuous-wave laser heating.
PAR4 (Protease-Activated Receptor 4): PARticularly Important 4 Antiplatelet Therapy.

Thrombin, the most potent platelet agonist in vivo, activates human platelets through PAR1 (protease-activated receptor 1) and PAR4 (protease-activated receptor 4) by proteolysis of the N terminus, which exposes the tethered ligands.1 Although these receptors are activated by the same mechanism, the overall sequence identity is only ≈33%, and each has a distinct mode of interaction with thrombin, which impacts the subsequent rates of proteolysis.2–4 PAR1 is an efficient substrate and responds to subnanomolar thrombin. In contrast, PAR4 requires ≈10-fold more thrombin for proteolysis. This difference led to the hypothesis that PAR4 was a redundant backup thrombin receptor, which limited the interest in developing PAR4 antagonists. See accompanying article on page 448 On further examination, the dual receptor system offers the intriguing possibility of pharmacologically fine-tuning thrombin signaling in platelets by taking advantage of the individual contributions of PAR1 and PAR4.5 Both receptors initiate signaling through Gq and G12/13 pathways but with distinct kinetics. PAR1 activation results in a rapid transient signal. In contrast, PAR4 mediates prolonged signaling that is required for stable thrombus formation (Figure [A]). Blocking the sustained signaling from PAR4 may limit thrombosis, while leaving the transient PAR1 signaling mechanism available to initiate hemostasis and limit bleeding (Figure [B]). With this goal in mind, PAR4 has been targeted with inhibitory antibodies, intracellular peptides, and small molecules.6–8 Several compounds that achieve PAR4 antagonism, such as YD-3 and ML354, are currently used as tools to study PAR4 …
Competitive dynamics across strategic groups: a literature review and validation by quantitative evidence of operation data

This research intends to: 1) critically evaluate and summarise recent years' literature of competitive dynamics across strategic groups in terms of competition mechanisms, particularly focusing on mobility barriers, multimarket contact and mutual forbearance; 2) validate the aforementioned competition mechanisms by analysing operation data, explicitly, inventory and pricing strategy from the US domestic airline industry; 3) offer explanations to inconsistencies revealed from the quantitative evidence to provide a better understanding of these competition mechanisms.
Immigration Courts, Judicial Acceleration, and the Intensification of Immigration Enforcement in the First Year of the Trump Administration

In this chapter, Austin Kocher provides an analysis of the immigration court system under the Trump regime. Kocher explains not only how this system functions as an apparatus of state exclusion, but how the immigration court is being radically reconfigured under Attorney General Jeff Sessions to strengthen this process of exclusion. As Kocher argues, the changes being made are designed to strip judges of discretion, limit opportunities for people with precarious citizenship status to remain in the United States legally, reduce the likelihood that these vulnerable people will obtain legal representation, and enroll the courts into the Trump regime’s drive to increase deportations at the expense of basic due process.
Spinoza's Political Psychology: The Taming of Fortune and Fear

Spinoza's Political Psychology advances a novel, comprehensive interpretation of Spinoza's political writings, exploring how his analysis of psychology informs his arguments for democracy and toleration. Justin Steinberg shows how Spinoza's political method resembles the Renaissance civic humanism in its view of governance as an adaptive craft that requires psychological attunement. He examines the ways that Spinoza deploys this realist method in the service of empowerment, suggesting that the state can affectively reorient and thereby liberate its citizens, but only if it attends to their actual motivational and epistemic capacities. His book will interest a range of readers in Spinoza studies and the history of political thought, as well as readers working in contemporary political theory.
Blockage Avoidance in Relay Paths for Roadside mmWave Backhaul Networks

With the increasing use of bandwidth-hungry applications on mobile devices, mmWave communication is considered a key enabling technology for 5G cellular networks. One very promising use of mmWave communication is in wireless backhaul for 5G. In this paper, we consider wireless backhaul links deployed along the side of a road, which will be a common scenario both in urban environments and on highways. We investigate blockage robustness within an interference-free topology previously proposed for roadside wireless backhaul. Reconfiguration algorithms are provided both for the case where rescheduling is possible after reconfiguration and for the case that the original transmission schedule must be maintained. We prove that our reconfiguration algorithms are guaranteed to maintain connectivity under several obstacle scenarios. We also evaluate the algorithms' performance with varying numbers of randomly-placed obstacles through simulation. Results show that our algorithms not only achieve high throughputs close to the no-blockage case, but also provide high blockage tolerance rates for the common case of a few obstacles along a several hundred meter section of a road.
Not missing the opportunity: Strategies to promote cultural humility among future nursing faculty.

Abstract As the demographics in the United States continue to change, nurses must deliver care to patients from diverse cultural backgrounds. Cultural humility is a lifelong process of self-reflection which is also defined by that individual. It allows an individual to be open to other people's identities, which is core to the nursing standard of providing holistic care. Embracing and incorporating cultural humility is essential for creating a comprehensive and individualized plan of care. One of the ways to achieve cultural humility in nursing is to train future faculty to become agents of cultural humility. This also helps to create a pipeline of nurses who have respect and empathy for the patients they serve. The aims of this paper include: 1) define cultural humility and its importance to healthcare professionals; 2) explore the intrapersonal, interpersonal, and system levels of cultural humility; 3) provide insight on how to promote cultural humility; 4) reflect on best practices across a variety of healthcare disciplines; and 5) provide suggestions for practice.
The Time-Scale of Recombination Rate Evolution in Great Apes

We present three linkage-disequilibrium (LD)-based recombination maps generated using whole-genome sequencing data of 10 Nigerian chimpanzees, 13 bonobos, and 15 western gorillas, collected as part of the Great Ape Genome Project (Prado-Martinez et al. 2013). Using species-specific PRDM9 sequences to predict potential binding sites, we identified an important role for PRDM9 in predicting recombination rate variation broadly across great apes. Our results are contrary to previous research that PRDM9 is not associated with recombination in western chimpanzees (Auton et al. 2012). Additionally, we show that fewer hotspots are shared among chimpanzee subspecies than within human populations, further narrowing the time-scale of complete hotspot turnover. We quantified the variation in the biased distribution of recombination rates towards recombination hotspots across great apes. We found that correlations between broad-scale recombination rates decline more rapidly than nucleotide divergence between species. We also compared the skew of recombination rates at centromeres and telomeres between species and show a skew from chromosome means extending as far as 10‐15 Mb from chromosome ends. Further, we examined broad-scale recombination rate changes near a translocation in gorillas and found minimal differences as compared to other great ape species perhaps because the coordinates relative to the chromosome ends were unaffected. Finally, based on multiple linear regression analysis, we found that various correlates of recombination rate persist throughout primates including repeats, diversity, divergence and local effective population size (Ne). Our study is the first to analyze within- and between-species genome-wide recombination rate variation in several close relatives.
Multiracial Campus Professionals’ Experiences with Racial Authenticity

ABSTRACTUtilizing critical Multiracial theory, this study explores how Multiracial campus professionals’ experiences with racial authenticity influence their work in postsecondary contexts. Three t...
Experimental study on effect of soy isoflavones on enhancment of mouse immune function

Objective:To explore the effect of soy isoflavones on enhancement of mouse immune function.Methods:Soy isoflavones were consecutively orally given to mice with the doses of 166.5 mg/kg,333.0 mg/kg and 666.0 mg/kg of body weight for 30～35 days and then various immune indexes were determined.Results:Soy isoflavones was capable of stimulating multiplication and transformation of mice′s spleen lymphocytes,promoting delayed hypersensitivity,increasing the quantity of antibody-producing cells,enhancing the level of serum hemolysin,promoting the expurgation effect and the phagocytic function of monocyte/macrophage and increasing the activity of natural killer.Conclusion:Soy isoflavones can enhance mouse immune function.
Environmental Telemonitoring: A Flexible GSM-DECT-Based Solution

This paper describes a low-cost standard solution for environmental monitoring. The advent of modern wireless communication technologies has added flexibility to data collection from remotely distributed sensors. In particular, nowadays, wireless Wide Area Networks like the Global System for Mobile communications (GSM) and satellite telephone services are ubiquitous: It has become feasible to collect data from remote sensors at locations which were previously inaccessible due to distance or extremely restrictive conditions. The shortcoming of this approach can be found in the need for a subscription to a telephone service provider. The authors propose to overcome this limitation, realizing a "local" cellular network exploiting a free and standard technology like "Digital Enhanced Cordless Telecommunications" (DECT), typically used for cordless handsets. The link with existing infrastructures can be satisfied with a sort of access point implementing, for example, both the DECT and GSM controllers. Working prototypes have been realized, and some experimental results have been reported. It has been possible to demonstrate the feasibility of a sampling station that is truly autonomous since it is battery powered.
Notes from The Archives: Researching Canadian Pentecostalism at the Holy Spirit Research Center, Oral Roberts University

A survey of resources concerning the Canadian Pentecostal and Charismatic Movements at Oral Roberts Unviersity.