cssi/SciSciGPT-SciSciNet huggingface dataset:
Health Information Without Limits: A Print Collection for Consumers in the Heart of the Hospital

ABSTRACTThe Health Information Center at the University of Tennessee Medical Center developed a consumer level print collection for patients, family members, and community visitors. Librarians utilized MLA Collection Development and Consumer and Patient Health Information Sections lists, vendor and consumer recommended lists, and Library Journal and other review sources. With input from key administrators for the six Centers of Excellence at the Medical Center, physicians, nurses, and pharmacists, 200 titles were selected and reviewed for appropriateness. The print collection is used in-house and regularly checked out by patients, family members, and the hospital community.
Analysis on Monitoring Result of Chloroacetate in Water Quality Network of Shenzhen City in 2009

[Objective]To analyze the content of chloroacetate in finished water and tap water of Shenzhen city.[Methods]The content of chloroacetate in water samples was analyzed and detected by gas chromatography,and the Standard for Drinking Water Quality was applied to evaluate.[Results]The limit of dichloroacetic acid (DCAA) and trichloroacetic acid (TCAA) was 0.05 mg/L and 0.1 mg/L respectively,and there was no result over the standards.[Conclusion]The contents of chloroacetate produced by different disinfection methods are different.There are many factors which can influence the production of by-products in chlorination disinfection of drinking water,and the types and concentrations of organic precursors in the source water is the decisive factors.
Methodology and Design of a Massively Parallel Memristive Stateful IMPLY Logic-Based Reconfigurable Architecture

Continued dimensional scaling of CMOS processes is approaching fundamental limits and, therefore, alternate new devices and microarchitectures are explored to address the growing need of area scaling and performance gain. New nanotechnologies, such as memristors, emerge. Memristors can be used to perform stateful logic with nanowire crossbars, which allows for implementation of very large binary networks. This paper involves the design of a memristor-based massively parallel datapath for various applications, specifically single instruction multiple data and parallel pipelines. The innovation of our approach is that the datapath design is based on space-time diagrams that use stateful IMPLY gates built from binary memristors. The paper also develops a new model and methodology to design massively parallel memristor-CMOS hybrid datapath architectures at a system level. This methodology is based on an innovative concept of two interacting subsystems: 1) a controller composed of a memristive RAM, MsRAM, to act as a pulse generator, along with a finite-state machine realized in CMOS, a CMOS counter, CMOS multiplexers, and CMOS decoders; 2) massively parallel pipelined datapath realized with a new variant of a CMOL-like nanowire crossbar array, memristive stateful CMOL with binary stateful memristor-based IMPLY gates. In contrast to previous memristor-based FPGA, our proposed memristive stateful logic field programmable gate array uses memristors for both memory and combinational logic implementation. With a regular structure of square abutting blocks of memristive nanowire crossbars and their short connections, our architecture is highly reconfigurable. We present the design of a pipelined Euclidean distance processor along with its various applications. Euclidean distance calculation is widely used by many neural network and similar algorithms.
Medical and surgical management of sinusitis in adults.

Sinusitis may be caused by bacteria, viruses, or trauma and may appear in immunosuppressive settings. Acute sinusitis is most commonly diagnosed on the basis of pain and discharge; endoscopic or fiberoptic examination may be helpful in less obvious cases. Radiography can identify maxillary, frontal, and sphenoid sinusitis; transillumination can be used if radiography is undesirable. Culture and Gram stains may help determine the appropriate antibiotic therapy. Surgery may be necessary if the frontal or sphenoid sinus is involved, or if ethmoiditis is progressing to orbital cellulitis
What Mechanisms Induce Methylation of FMR1 Gene Full Mutation? A Still Unanswered Question

The fragile X syndrome (FXS) is the most frequent form of inherited intellectual disability and autism, for which there is currently no cure. In the vast majority of FXS patients, the FMR1 gene is inactivated by epigenetic changes secondary to expansion of a CGG repeat. FMR1 encodes the fragile X mental retardation protein (FMRP) involved in multiple aspects of mRNA metabolism in the brain. Many mRNAs that are dysregulated in the absence of FMRP encode synaptic proteins, causing a characteristically abnormal morphogenesis of dendritic spines. Methylation of FMR1 full mutation is estimated to occur around 10–12 weeks of gestation, resulting in block of transcription. The molecular mechanisms involved in this particular type of methylation are still unknown. Amidst fragile X families, there are rare males who, in spite of having inherited a full mutation (usually of small dimensions between 200 and 300 CGG repeats), are unable to methylate it. These individuals produce enough FMRP protein to allow an intellectual development within normal range. What factors are responsible for the rescue of these individuals from being affected with the fragile X syndrome? In an effort to answer this crucial question, which may have consequences for a cure, several potential regulatory factors have been studied so far. The identification of molecular and cellular pathways underlying the pathogenesis of FXS that may be targetable by drugs with potential therapeutic value remains the ultimate goal. Here we produce a critical revision of the present knowledge about the syndrome and its epigenetic pathogenesis.
GQ: The Guantanamo Quagmire

Accepting for argument’s sake the twin premises that sending Operation Enduring Freedom detainees to Guantanamo Bay (GTMO) was in line with the international and domestic law of detention as it then existed, and that detaining suspected terrorists at GTMO achieved its core purpose of removing threats from the battlefield, and further allowed for the collection of useful intelligence from the detainees, this article examines why the GTMO is considered by many to be a “lightning rod,” a “political football,” or even an “albatross.” As I have previously written, the government’s ultimate inability to successfully defend its application of prior habeas precedents has had significant legal consequences, including operational law incentives to lethally target combatants, and the development of international guidelines to fill supposed “legal ambiguities” in the rules troops must apply when detaining enemy forces in international armed conflicts. See “Meaningful Review and Process Due: How Guantanamo Detention is Changing the Battlefield,” Harvard National Security Journal (2015) - http://ssrn.com/abstract=2560152. This article further examines the relationships and differences between law, policy, and politics in the context of detainee-related operations at GTMO. Taking a broad view of foreign policy and international relations, it examines how related but nonetheless discrete issues (e.g., law of war detention at GTMO versus intelligence interrogation at black sites) have been conflated in ways that have long-term legal and policy consequences, and that the name “Guantanamo Bay” is thus a cue for controversies that are perhaps as often mythical as grounded in fact. Part I traces the evolution of American foreign policy and global leadership as driven by moral values. Part II examines two post-9/11 counterterrorism detention scandals often discussed in tandem with (if not entirely conflated with) GTMO — the Central Intelligence Agency’s (CIA) so-called rendition, detention, and interrogation (RDI) program, and the Abu Ghraib prisoner abuse scandal — that undercut the moral high ground and human rights focus around which successive presidential administrations conducted international relations. Part III analyzes the dynamics of modern communications and the influence of globalized, decentralized, and instant reporting of news on U.S. national security policymaking, particularly with respect to GTMO and detention-related issues. Part IV concludes by laying out the long-term consequences of the resulting dubious conventional wisdom that several aspects of U.S. detention policy violate international law, and asserts that a significant factor in GTMO’s supposed radioactivity has been self-imposed by failing adequately to articulate and defend legal and strategic decisions made early on, and subsequently adopting the human rights community’s talking points in high-level political rhetoric, which have made GTMO more politically toxic than necessary.
Optimization and evaluation of reference region variable flip angle (RR-VFA) B1+ and T1 Mapping in the Prostate at 3T.

Purpose To optimize and evaluate the reference region variable flip angle (RR-VFA) technique for simultaneous B1+ and T1 mapping of the prostate at 3 Tesla (T). Materials and methods The fat region surrounding the prostate was first identified using a fractional fat segmentation constant (tF ) and a signal fat-fraction threshold (rF ), and the relative flip angle (FA) was characterized using an effective fat T1 (T1f ) within the fat region. Optimal values of tF , rF , and T1f were chosen by comparing relative FA maps using RR-VFA (ARR-VFA ) with a reference relative FA maps (AREF ) in the surrounding fat and evaluating interpolation errors within the prostate. The optimized RR-VFA was evaluated in volunteers at 3T on a single scanner (n = 10) and across three scanners (n = 4). Results tF , rF and T1f were optimized as 0.5, 90%, and 320 ms, respectively. Prostate ARR-VFA showed differences of 30% among volunteers on one scanner, with no significant differences between ARR-VFA and AREF (P = 0.41). Prostate T1 after B1+ correction was 1998 ± 113 ms with significantly (P = 0.004) lower standard deviation than T1 before B1+ correction. The average coefficient of variation of prostate T1 across multiple scanners decreased from 15% to 5% after B1+ correction. Conclusion The optimized RR-VFA can simultaneously measure B1+ and T1 in the prostate without the need for an additional scan and improve T1 consistency within and across MRI scanners at 3T. Level of evidence 3 J. Magn. Reson. Imaging 2017;45:751-760.
Small-Area Si Photovoltaics for Low-Flux Infrared Energy Harvesting

Silicon photovoltaics are prospective candidates to power mm-scale implantable devices. These applications require excellent performance for small-area cells under low-flux illumination condition, which is not commonly achieved for silicon cells due to shunt leakage and recombination losses. Small area (1–10 mm $^{2}$ ) silicon photovoltaic cells are studied in this paper, where performance improvements are demonstrated using a surface n-type doped emitter and Si3N4 passivation. A power conversion efficiency of more than 17% is achieved for 660-nW/mm2 illumination at 850 nm. The silicon cells demonstrate improved power conversion efficiency and reduced degradation under low illumination conditions in comparison with conventional crystalline silicon photovoltaic cells available commercially.
The fight is the coach: creating expertise during the fight to avoid entrepreneurial failure

Purpose The purpose of this paper is to explain how the process that occurs before an entrepreneurial failure event provides a coached learning setting that creates entrepreneurial expertise. Design/methodology/approach This is a conceptual paper drawing on the literatures of expert information processing theory and deliberate-practice expertise development to suggest a model and propositions that flow from the analysis. Findings Adding to the expert performance literature – specifically the introduction of the notion of emergent practice – this paper proposes that the intensity of the fight to avoid entrepreneurial failure, the duration of the fight, the content required in that fight, and the clarity and rapidity of feedback received, are associated with the creation of entrepreneurial expertise. Research limitations/implications This paper complements research on learning from failure by exploring how significant learning before entrepreneurial failure either occurs or is avoided, can lead to the creation of entrepreneurial expertise. Practical implications This research provides guidance for entrepreneurs engaged in the fight to avoid entrepreneurial failure, and suggests ways for prospective supporters to better assess entrepreneurs with failed ventures in their history. Originality/value The paper applies the deliberate-practice concept, common in sports, games, and the arts, to an “emergent practice” setting; that is, within a real-life (marketplace) setting within which the “fight” to avoid entrepreneurial failure functions as the “coach”; and it describes how the learning necessary for the creation of entrepreneurial expertise likely takes place.
Telepsychiatry Consultation for Medical and Surgical Inpatient Units

Background Telepsychiatry is becoming more commonplace in the provision of psychiatric care. Most commonly used in the outpatient setting, there is little information available in the literature as to the use of telepsychiatry for inpatient medical/surgical consultation. Objective We review the University of Pittsburgh Medical Center's telepsychiatry consultation program that provides consultation to an outlying community-based rural hospital. Methods This article examines the 69 telepsychiatry consultations that were performed from November 2014 through February 2016, looking at the patients served, common consultation questions, and patterns of diagnoses and recommendations. Results The median age of individuals undergoing telepsychiatry evaluations was 67 years, and the most common reason for consultation was for delirium. Over half of the patients consulted had a primary diagnosis of delirium, dementia, or a cognitive disorder not otherwise specified, using Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition, Text Revision) diagnoses. In most patients, additional laboratory studies or imaging or both were requested and medication changes recommended (initiation, dose changes, and discontinuation). Conclusion This report provides one of the first detailed views of the use of telepsychiatry in a remote inpatient medical setting. Findings will guide education to primary teams and will shape the development of future telepsychiatry interventions.
Maxima of Random Quadratic Forms on a Simplex

Publisher Summary This chapter discusses the maxima of random quadratic forms on a simplex. In recent times, it has become evident that the number of alleles that can be produced by mutation at a locus may be very large. There is no need to assume that they are all present at some initial epoch; more probably, they arise from time to time by mutation and the effects of selection and mutation alternate. The application of the Dirichlet distribution also suggests that it might be impossible to distinguish, by statistical analysis of a number of polymorphisms, whether single-locus selection is the underlying mechanism.
An Integrated Framework for Users’ Well-Being

The hygro-thermal comfort (ICQ) is defined as the psychophysical state in which the subject expresses a condition of well-being with respect to environmental variables, a condition known as thermal neutrality. Furthermore, the ICQ represents one pillar of the holistic concept of the Indoor Environmental Quality (IEQ). The methods for the assessment of ICQ and recognized at international level are mainly two. The former, based on a steady-state approach, described by the EN ISO 7730:2005 and applied to Fully Mechanically Controlled buildings (FMC) equipped with an active conditioning system. The latter, based on an adaptive approach, as defined trough in field activities and described by the technical standard ASHRAE 55 and EN 15,251, instead, considers the users as active subjects that interact with surrounding environment and are influenced in their comfort perception by external conditions. In this case, the thermal comfort concept is not just defined depending on physical, but also psychological, social, economic and cultural aspects. The technical standards provides that this method could be applied in middle seasons when the control of comfort is handled by passive technological methods, i.e., in the so called Natural Ventilated or Free Running buildings (FR). In this approach, methodologies providing the direct involvement of the end user are consolidating, through the collection of physiological, psychological and behavioral personal data as to obtain the better assessment of the comfort conditions. Placing in this field, the article describes the results of a field investigation in an office aimed at defining a framework for the assessment of the thermal comfort based on the two approaches through the use of low cost technology solutions, parametric and freeware models.
Pathways to pleasure: Older adult women’s reflections on being sexual beings

ABSTRACTOlder adult women make up a growing part of the population, and yet literature on the sexual activity over their life spans is lacking. This qualitative interview study explored the experience of 16 women aged 57–91 to better understand sexual pleasure over a lifetime. The participants described having to challenge cultural rules to create a supportive environment for sexual expression. Having access to Novel contexts in which to learn, cultivating Intimacy with partners and with oneself, being Creative with sexual activities, and Extending one’s sense of sexual possibility into advanced age (NICE) supported sexual pleasure as women aged.
Novel approaches for quantitative electrogram analysis for intraprocedural guidance for catheter ablation: A case of a patient with persistent atrial fibrillation.

Purpose Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia that causes stroke affecting more than 2.3 million people in the US and is increasing in prevalence due to ageing population causing a new global epidemic. Catheter ablation with pulmonary vein isolation (PVI) to terminate AF is successful for paroxysmal AF but suffers limitations with persistent AF patients as current mapping methods cannot identify AF active substrates outside of PVI region. Recent evidences in the mechanistic understating of AF pathophysiology suggest that ectopic activity, localized re-entrant circuit with fibrillatory propagation and multiple circuit re-entries may all be involved in human AF. The authors developed novel electrogram analysis methods and validated using optical mapping data from isolated rabbit hearts to accurately identify rotor pivot points. The purpose of this study was to assess the feasibility of generating patient-specific 3D maps for intraprocedural guidance for catheter ablation using intracardiac electrograms from a persistent AF patient using novel electrogram analysis methods. Methods A persistent AF patient with clinical appointment for AF ablation was recruited for this study with IRB approval. 1055 electrograms throughout the left and right atrium were obtained for offline analysis with the novel approaches such as multiscale entropy, multiscale frequency, recurrence period density entropy, kurtosis and empirical mode decomposition to generate patient specific 3D maps. 3D Shannon Entropy, Renyi Entropy and Dominant frequency maps were also generated for comparison purposes along with local activation time and complex fractionated electrogram analysis maps. Results Patient specific 3D maps were obtained for each of the different approach. The 3D maps indicate potential active sites outside the PVI region. However, presence of rotors cannot be confirmed and validation of these approaches is required on a larger dataset. Conclusions Conventional catheter mapping system can be used for generating patient specific 3D maps with short time series analysis using the novel approaches.
The critical factors & loading features in design inductive heating-device

The inductive heating technique has been studied popularly by many scholars all over the world. Today the inductive heating facilities have been applied in many manufacturing tools of many fields in Taiwan, and this promoted research in this field directing to higher power, higher frequency, and higher efficiency as well. This study was pilot study for practical design of resonated heating circuit with half-bridge resonated inverter, especially some critical factors when considering the loading features including its primary theory, skin effects, permeance, conductance, and loading features. With this pilot-study, we would implement it into our further advanced research in high-power heating facilities with Half-Bridge Resonated Inverter.
MIS Patellofemoral Arthroplasty

The prevalence of isolated patellofemoral arthritis is high, occurring in as many as 11% of men and 24% of women older than the age of 55 years with symptomatic osteoarthritis of the knee in one study.1 Symptomatic patellofemoral chondromalacia occurs with even greater frequency and is a very common reason for presentation for orthopedic evaluation, particularly in women between the ages of 30 and 50 years. This gender predilection is undoubtedly related to the often subtle patellar malalignment and dysplasia that is common in women. The patellofemoral cartilage is also at risk for direct traumatic injury, considering its vulnerable location in the body.
Why Black entrepreneurs are motivated and persistent despite lower business performance

Grounded in AMO (ability, motivation, opportunity) theory, this study takes a first step at bringing race back into the entrepreneurship literature to predict how the race of the founding entrepren...
Wagner Syndrome and Stickler Syndrome

The characteristic features of Wagner syndrome include myopia, an optically empty vitreous, preretinal membranes, perivascular retinal pigment epithelial changes, vascular sheathing, cataracts, and atrophy of the choriocapillaris. The cataracts typically appear as patients approach their 40th birthday. The vitreous bands are broad and insert into the peripheral retina; and there is liquefaction of the vitreous. It is autosomal dominant and usually present bilaturally. It is noteworthy that many physicians consider Wagner syndrome to be a mild form of Stickler syndrome. Wagner syndrome patients, however, do not have systemic changes, whereas Stickler syndrome patients have systemic manifestations. The former patients do not suffer retinal detachments, whereas more than 50% of the Stickler syndrome patients develop a retinal detachment.
Evaluating comfort measures for commonly performed painful procedures in pediatric patients.

Introduction Management of pediatric pain from medical procedures is of great importance for improving both patient care and experience. In this study, we investigated methods of managing acute pain in infants and children by studying the correlation between the number of attempts to complete painful procedures, given different comfort measures. Methods The study is a retrospective review of 74,276 procedures performed at two pediatric hospitals in an integrated academic children's health system between 2013 and 2016. We compared three comfort measures most frequently offered: positions of comfort (POC), distraction (DIST), and pharmacological (PHARM). These methods were compared in the setting of four procedures: peripheral intravenous (PIV) catheter insertion, gastrointestinal tube placement, incision procedures, and bladder catheterization. We used the number of attempts needed to complete a procedure as a measure of efficacy minimizing distressing experience in an acutely painful setting (single attempt vs repeat attempts). Results Among younger children, DIST appears superior to the other two methods; it performs significantly better for three of the four procedures (PIV catheterization, incision wound, and urinary catheterization) among infants aged <1 year and for PIV catheterization among toddlers aged 1-3 years. For older children, POC tends to perform slightly better than the other two methods, although it is significantly better only for PIV catheterization among adolescents aged 13-21 years and urinary catheterization among children aged 9-12 years. Conclusion Results from this study may be used to determine appropriate comfort measures for painful procedures in pediatric setting.
iDEG: A single-subject method for assessing gene differential expression from two transcriptomes of an individual

Accurate profiling of gene expression in a single subject has the potential to be a powerful precision medicine tool, useful for unveiling individual disease mechanisms and responses. However, most expression analysis tools for RNA-sequencing (RNA-Seq) data require replicate samples to estimate gene-wise data variability and make inferences, which is costly and not easily obtainable in clinical practice. We propose the iDEG method to identify individualized Differentially Expressed Genes in a single subject sampled under two conditions without replicates, i.e. a baseline sample (unaffected tissue) vs. a case sample (tumor). iDEG borrows information across different genes from the same individual using a partitioned window to strategically bypass the requirement of replicates per condition. It then transforms RNA-Seq data such that, under the null hypothesis, differences of transformed expression counts follow a distribution and variance calculated across a local partition of related transcripts at baseline expression. This transformation enables modeling genes with a two-group mixture model from which the probability of differential expression for each gene is then estimated by an empirical Bayes approach with a local false discovery rate control. Our extensive simulation studies demonstrate iDEGs substantially was the only technique keeping high precision (>90%), recall (>75%) and low false positive rate (<1%) accuracy under thousands of scenarios when compared to DESeq, edgeR, and DEGseq. Software available at: http://www.lussiergroup.org/publications/iDEG
THE BENEFITS OF GRANDPARENTING WHEN GRANDPARENTS OR GRANDCHILDREN ARE NOT AVAILABLE

Grandparent-grandchild relationships can contribute to individual development and relational health. However, these relationships are not always available to the youth and elders who might join them. Families emigrating from other countries may leave grandparents behind and have limited opportunity for exchange of cultural traditions, for example. Even when a grandparent-grandchild relationship exists, the relationship quality may be poor, denying members the chance to benefit from familial intergenerational contact. For these and other reasons, the potential benefits of non-familial intergenerational relationships should be considered. The current presentation addresses address non-familial intergenerational relationships that allow youth and elders to experience grandparent-like relationships when grandparents or grandchildren may not be available to each other, giving consideration to contemporary demographic, structural, and historical influences affecting availability of familial intergenerational relationships, theories addressing the imperative of intergenerational relationships, and evidence of the impact of non-familial intergenerational contact on youth and on elders.
Accuracy and Reliability of Root Crack and Fracture Detection in Teeth Using Magnetic Resonance Imaging.

Abstract Introduction Magnetic resonance imaging (MRI) has the potential to aid in determining the presence and extent of cracks/fractures in teeth because of better contrast without ionizing radiation. The objectives were to develop MRI criteria for root crack/fracture identification and to establish reliability and accuracy in their detection. Methods MRI-based criteria for crack/fracture appearance was developed by an MRI physicist and a panel of 6 dentists. Twenty-nine human adult teeth previously extracted after a clinical diagnosis of a root crack/fracture were frequency matched to 29 controls. Samples were scanned using an in vivo MRI protocol and the reference standard (ie, ex vivo limited field of view cone-beam computed tomographic [CBCT] imaging). A blinded, 4-member panel evaluated the images with a proportion randomly retested to establish intrarater reliability. Overall observer agreement, sensitivity, and specificity were computed for each imaging modality. Results Subjectively, MRI has increased crack/fracture contrast and is less prone to artifacts from radiodense materials relative to CBCT imaging. Intrarater reliability for MRI was fair to excellent (κ = 0.38–1.00), and for CBCT imaging, it was moderate to excellent (κ = 0.66–1.00). Sensitivity for MRI was 0.59 (95% confidence interval [CI], 0.39-0.76; P = .46), and for CBCT imaging, it was 0.59 (95% CI, 0.59–0.76; P = .46). Specificity for MRI was 0.83 (95% CI, 0.64–0.94; P Conclusions Despite advantages of increased contrast and the absence of artifacts from radiodense materials in MRI, comparable measures of sensitivity and specificity (to limited field of view CBCT imaging) suggest MRI quality improvements are needed, specifically in image acquisition and postprocessing parameters. Given the early stage of technology development, there may be a use for MRI in detecting cracks/fractures in teeth.
Barriers to Psychologists’ Adherence to Evidence-Based Practice Guidelines for Treating Musculoskeletal Injuries Within the State Insurance Regulatory Authority Compensation Schemes

Objectives:The use of evidence-based practice (EBP) guidelines by psychologists working within the State Insurance Regulatory Authority (SIRA) compensation schemes for treating musculoskeletal injuries has been found to vary. The aim of this study was to qualitatively explore psychologists’ perceived barriers to adhering with EBP guidelines implemented by the New South Wales (NSW) SIRA.Methods:Registered psychologists (n = 20) working within the NSW SIRA compensation schemes participated in four focus groups conducted face-to-face (F2F) and online. Participants’ responses were audiotaped, transcribed verbatim and entered into NVivo 11 software. Text data were analysed to identify recurrent themes within and across groups (metropolitan, regional and rural).Results:Thematic analysis revealed three key issues: (a) a lack of trust in the validity of the recommended EBP guidelines; (b) lack of knowledge of the psychologist’s role in this context and insufficient skills to fully apply the guidelines, protocols and procedures; and (c) a poor fit between EBP guidelines, client presentations and circumstances, and the SIRA compensation schemes.ConclusionThe findings showed that both individual practitioner variables and contextual barriers influenced adherence to EBP. Practical implications for future research include generating recommendations to overcome the identified barriers using a collaborative approach between policymakers, researchers and practitioners.
Does Privacy Matters When We are Sick? An Extended Privacy Calculus Model for Healthcare Technology Adoption Behavior

Patients’ acceptance of healthcare-technology is crucial for better and more affordable healthcare. However, there is evidence that some patients believe using healthcare-technology is a threat to the privacy of their health-related information. Privacy calculus is a widely accepted theory to explain technology adoption behavior when it involves disclosure of personal information. The applicability and effectiveness of privacy calculus model in explaining healthcare technology adoption behavior is still unknown and requires further investigation. In this study, we propose an extended privacy calculus model incorporating health condition emotion as an additional factor that interplays with the two privacy calculus factors. We tested our model with responses from 239 participants. The results revealed that health emotion related to individuals’ on-going health condition interact with the privacy calculus components to influence their health-related technology adoption decisions. The results have important implications for both theory and practice in healthcare domain.
Acoustic droplet vaporization embedded in 3-D printed gelatin methacrylate hydrogels

Gelatin Methacrylate (GelMA) is a popular hydrogel used for tissue engineering applications due to its biocompatibility, tunable mechanical properties, and rapid reproducibility. With its ability to be crosslinked with ultraviolet light exposure, GelMA can be 3-D printed into a variety of different shapes and geometries for customization for patient needs. We embedded phase-shift perfluorocarbon nanodroplets within the GelMA resin prior to 3-D printing. The droplets were then vaporized by external acoustic excitations determining the acoustic droplet vaporization (ADV) and inertial cavitation (IC) thresholds of the embedded droplets. The ADV of embedded droplets in a tissue engineering scaffolds can be used for triggered release of droplet contents. Varying the size and liquid core composition of the droplets as well as the mechanical properties of GelMA, one can change the ADV and IC characteristics of the embedded droplets. We will present the results of our experiments and discuss their implications on the potential use of this technology in tissue engineering.
Frequency Computation During Events and Point-on-wave Measurement

Point-on-wave (POW) technique features high sampling rate and GPS-synchronized sampling, which enable it to record transient waveforms conveniently with accurate time stamp. During a transmission line fault, the resulted fast oscillation and voltage sag bring troubles to the monitoring devices which compute the frequency in real time. It is demanding to improve the accuracy of existing frequency calculation algorithms. This paper focuses on comparing the performance of four frequency computing algorithms by two fault conditions including a phase-to-ground fault and a phase-to-phase fault happened near peak. The result shows that all the algorithms have large fluctuation during a phase-to-phase fault due to the existence of phase shift. Two characteristic points on a waveform, namely the point-of-inception (POI) and point-of-recovery (POR) is identified by the algorithms on the phasor complex plane, which represent the start and the end of an event respectively. The waveform between POI and POR is effectively smoothed by a Kalman filter, which enhances the computation stability.
Applying Research to Design Online Learning Environments

Online learning environments (OLEs) are at a stage where research in online learning and pedagogy can be used to influence the design and technical featuresets of these software platforms. To date, most OLEs are technical modifications of existing discussion software, and not platforms built specifically with the on-line learner and facilitator in mind. Concentrating on the development of a textbased asynchronous learning network (ALN), we seek to harvest a number of best practices in on-line learning, supported by research; examine the technological and learner-centered affordances and caveats concerning OLEs; building an analytical framework with which to measure our progress in terms of creating social, cognitive, and teaching presences; and finally proposing a number of recommendations for the design and implementation of OLEs.
Dominant Democracies: The Domestic Sources of International Hegemony

What determines whether great powers maintain their position in the international system, or cede it to other rising powers? Drawing on the writings of Polybius, Machiavelli, Montesquieu, and recent research in economics and political science, I develop a theory of democratic dominance that links domestic political institutions to global hegemony. I argue that democratic institutions provide states with a number of advantages that better enable them to maintain their structural position in the international system: democratic countries enjoy higher, long-run rates of economic growth; are better able to raise capital in international financial markets; adopt alliance management techniques that provoke less international resistance; are less likely to lose international wars; and, when defeated on the battlefield, are less likely to lose disastrously. An empirical analysis on data from 1815 to the present provides support for these theoretical claims. This research provides a new theory of, and the first systematic empirical investigation into, the sources of global hegemony and suggests a number of important policy implications.
Chapter 12 – Monitoring Disinfectants

Publisher Summary Disinfection is a process that deliberately reduces the number of pathogenic microorganisms in water to achieve the principal objective of drinking water treatment: protection of public health. Disinfection of water is often needed to assure its drinkability. The use of chemical disinfectants was made in as large quantities as required to achieve the desired quality. Currently, there are several options for the disinfection of drinking water, each with its own merits as a disinfectant and the presence of by-products that must be minimized. The disinfection process is expected to satisfy the following three requirements: inactivation of the pathogenic and other harmful microorganisms in water (primary disinfection), disinfectant residual maintenance in the distribution system (secondary disinfection), and keeping the amount of by-products to a minimum. Different disinfectants offer different performances toward the achievement of these three requirements. Regular monitoring is the responsibility of the public water system. A certified drinking water laboratory must analyze collected samples. It is required that disinfectant residual be measured monthly at the end of each treatment process that uses chlorine.
Antacid-induced acute hypercalcemia: An increasingly common and potentially dangerous occurrence:

Hypercalcemia is frequently encountered in both hospital wards and the primary care setting; 90% of cases can be attributed to primary hyperparathyroidism and malignancy. However, a minority are caused by medications, of which calcium supplements have been an increasingly common etiology. We are presenting a case of hypercalcemia resulted after acute oral intake of a moderate amount of antacids (calcium tablets) and normalized after supplement withdrawal.
Explore the export performance of textiles and apparel ‘Made in the USA’: a firm-level analysis

This study explored the export behaviors of the U.S. textile and apparel (T&A) manufacturers and related affecting factors. Based on a logistic regression analysis of the 122 U.S. T&A manufacturers...
Simultaneous determination of succinylcholine and its metabolite in animal‐derived foods by solid‐phase extraction combined with ultra‐performance liquid chromatography/mass spectrometry

Rationale Succinylcholine has been increasingly used in theft of animals. Due to the presence of residual levels of succinylcholine in poisoned animals, it is harmful for people to eat foods derived from these animals. Therefore, it is urgent that a method should be established for the determination of succinylcholine and its metabolite in animal-derived foods. Methods A fast, highly sensitive method, combining solid-phase extraction (SPE) with ultra-performance liquid chromatography-electrospray ionization tandem mass spectrometry (UPLC/ESI-MS/MS), was developed for the determination of succinylcholine and its metabolites in animal-derived foods. The sample is initially extracted with heptafluorobutyric acid and then further cleaned up with an SPE cartridge. Succinylcholine and its metabolites are separated using acetonitrile: 0.1% formic acid in 5 mmol L-1 ammonium acetate as the mobile phase. Quantitative results are based on positive ion ESI multiple reaction monitoring mode. Results The results show good linearity over a wide range with correlation coefficients of determination of more than 0.998. The limits of detection of succinylcholine and succinylmonocholine are both 0.2 μg kg-1 . The intra- and inter-day accuracies of the method were in the range 91.4%-104.6% and the intra- and inter-day precisions were in the range 2.5%-6.6%,. Conclusions This method can be used for the determination of succinylcholine as an illicit drug in animal-derived foods. It was successfully applied to identification and quantification of succinylcholine and succinylmonocholine in animal-derived foods collected from a local farmers market in Jilin province of China.
Abstract PO042: Oncostatin M receptor as a therapeutic target of radioimmune therapy in metastatic synovial sarcoma

Synovial sarcoma is a soft tissue malignancy of the muscle tissue which primarily affects adolescents. While it is a rare disease, little advancement has been made in the treatment of this cancer. With an overall survival rate of roughly 40%, the need for new treatments for synovial sarcoma is evident. Oncostatin M Receptor (OSMR) is a type I cytokine receptor and is overexpressed in metastatic synovial sarcoma. OSMR does not have high expression in normal tissues, making it an ideal target for cancer therapy. We hypothesize that by using an anti-OSMR monoclonal antibody conjugated to a radioactive Cu67 isotope, synovial sarcoma can be targeted at both primary and metastatic locations through systemic therapy. Copper 67 is a gamma radiation emitting isotope which is tissue damaging and able to induce cell death in cancer cells. By conjugating the chelating molecule p-SCN-Bn-NOTA to an anti-OSMR antibody, Cu67 was able to be captured to the antibody. Capture efficiency of Cu67 was measured through TLC and found to be 64 % efficient. Binding studies through Surface Plasmon Resonance (SPR) found that the conjugation did not interfere with the binding affinity of the antibody. This data suggests that targeting OSMR through radio-immune therapy is a viable treatment and indicates further testing in animal models. Citation Format: Sarah Luelling. Oncostatin M receptor as a therapeutic target of radio-immune therapy in metastatic synovial sarcoma [abstract]. In: Proceedings of the Annual Meeting of the American Association for Cancer Research 2020; 2020 Apr 27-28 and Jun 22-24. Philadelphia (PA): AACR; Cancer Res 2020;80(16 Suppl):Abstract nr 529.
Schooling the Eye and Hand: Performative Methods of Research and Pedagogy in the Making and Knowing Project.

What are historians doing in the laboratory? Looking back over six years of collaborative work, researchers of the Making and Knowing Project at Columbia University discuss their experience with hands-on reconstruction as a historical method. This work engages practical forms of knowledge-from pigment-making to metal casting-recorded in the BnF Ms. Fr. 640, an anonymous French manuscript compiled in the later sixteenth century. Bodily encounters with materials and processes of the past offer insights into the material and mental worlds of early modern artists and artisans, and train the eye in the interpretation of historical objects. At the same time, reconstruction contributes to the interpretation of the text: it is only by attempting to implement the instructions of practical or recipe literature that these texts can be understood as vehicles of emergent knowledge that only fully manifests itself in the doing. Overall, our approach to reconstruction mirrors that of the anonymous author-practitioner, who explored a wide range of techniques through experimenting and writing.
The spiritual transformation of giving: Generosity’s constitution of the self and community in post-religious society:

How has the ‘benevolent self’s relation to others changed as a result of (first) the liberalization of monotheisms and (then) the uneven transition to post-religious spiritual formations? The appar...
Pairing geothermal technology and solar photovoltaics for net-zero energy homes

Abstract Homeowners across the globe are continually seeking methods of improving energy efficiency for financial benefit and personal satisfaction. From small contributions such as swapping light bulbs to large capital investment initiatives like upgraded heating and cooling systems, homeowner decisions require accurate data and confidence in potential outcomes. This study models the path to net-zero energy for two separate heating, ventilation and air conditioning (HVAC) plus solar photovoltaic (PV) systems in residential buildings across 12 Unites States climate zones, and determines the optimal combination for each climate zone. An existing, traditional air-conditioning system with natural gas furnace is paired with a PV array. The net-zero results are compared to the same residence upgraded to a climate-customized geothermal heat pump HVAC system paired with a PV array. Results confidently favor the geothermal HVAC system + PV for climates with a significant heating demand in winter, and the baseline + PV system for cooling-dominant climates, exceeding $3,900 and $3,500 annual household savings, respectively. A major contribution is the introduction of a template that predicts the net-zero system option for climate zones outside the 12 studied. Patterns in local soil properties, sun intensity and financial incentives allow for net-zero system predictions nationwide. For example, all locations resulting in a baseline + PV net-zero system have strong sun intensity ratings. This research delivers climate-specific recommendations for the preferred net-zero HVAC + PV system through analysis of accurate energy performance and financial forecasting. Recommendations provide homeowners with valuable expectations on two HVAC + PV options along the path to a net-zero energy home.
The Perfect Storm: Using Snowstorms to Analyze the Effect of Theatrical Attendance on the Demand for Subsequently Released DVDs

Movies are distributed through multiple, carefully segmented, channels. This paper investigates how consumption in a movie’s theatrical channel affects demand in the subsequent DVD retail channel. We exploit exogenous variation in events that affect theatrical attendance in a geographic market to estimate the causal impact of theater attendance on home entertainment demand. Specifically, we use the occurrence of major snowstorms surrounding a movie’s theatrical opening weekend as an exogenous shock to theatrical demand in a local market.Using this instrumental variable (IV) approach, we find evidence that theatrical attendance causally impacts home entertainment demand: lower theatrical attendance in a geographical market that experiences an opening weekend snowstorm leads to lower DVD/Blu-ray sales in the movie’s subsequent home entertainment release window in that geographical market. Specifically, we estimate a 10 percent rise (drop) in theatrical attendance causes an approximate 8 percent increase (decrease) in the volume of DVDs/Blu-ray discs sold in the first eight weeks of the DVD release window. This result provides important managerial guidance in an industry undergoing significant changes in the how movies are marketed across theatrical and home entertainment channels.
The Impacts of Terrorism and Capitalist Incorporation on Indigenous Americans

This article demonstrates the connections between terrorism, colonial state formation, and the development of the capitalist world system, or globalization, exploring the consequences of colonial terrorism on indigenous American peoples. First, the piece introduces the central argument and conceptualizes and theorizes terrorism. Second, it examines the structural aspects of colonial terrorism by connecting it to specific colonial policies and practices. Third, it explains the ideological justifications that Euro-American colonial settlers and their descendants used in committing crimes against humanity and dispossessing the homelands of indigenous Americans, as well as in amassing wealth/capital by ignoring moral, ethical, and philosophical issues and human rights.