cssi/SciSciGPT-SciSciNet huggingface dataset:
New-Onset Diabetes Mellitus With Exposure to Ledipasvir and Sofosbuvir

The combination therapy of ledipasvir/sofosbuvir was approved by the Food and Drug Administration in 2014 for the treatment of chronic hepatitis C. Although hyperglycemia is not well known to occur with its use, we present 2 cases of new-onset diabetes mellitus and a review of the literature suggesting an adverse event association. In the first patient with HIV, we postulate that ledipasvir/sofosbuvir increased the levels of tenofovir and thereby potentiated hyperglycemia. In the second case of a patient with prediabetes, ledipasvir/sofosbuvir appeared to increase insulin resistance. A literature review further supported an association of hyperglycemia and the use of ledipasvir/sofosbuvir. Hence, clinicians should be cautious about worsening of glucose intolerance, and more studies are warranted to explore the underlying mechanism.
Flaps for cleft lip and palate surgery

The advantages of palate repair by double opposing Z-plasty include excellent access for complete mobilization of the palatal muscles, construction of an overlapping muscle sling, and avoidance of the growth-limiting horseshoe-type scars of the hard palate that result from lateral relaxing incisions or pushback procedures. The excellent speech that results seems to justify use of the procedure. An Abbe flap designed to mimic the normal philtrum placed over an interlacing orbicularis reconstruction that is well supported superiorly can salvage a thin, scarred upper lip and improve its mobility. The lateral gingival flap provides excellent esthetic reconstruction of the cleft alveolus, secure cover over an alveolar bone graft, and ease closure of an anterior oronasal fistula.
Parabolised model of the turbulent wake behind marine turbines

The extraction of hydrokinetic energy from ocean currents or tides involves the use of marine turbines generating turbulent wakes. The prediction of the wake characteristics is essential because the velocity deficit and increased levels in turbulence intensity dictate the interaction between turbines and any environment impact. A numerical methodology combining the parabolised Navier–Stokes equations with a modified actuator-disk model is presented. The main innovation of the modified actuator-disk model is that the flow is considered to be non-uniform downstream of the turbine. The numerical method is used to reproduce the experiments of Neary et al. (2013) and Mycek et al. (2014). The computational results show that the modification in the actuator-disk model aids in the reproduction of the experimental measurements. The simulations also show that increased levels in the ambient turbulence intensity cause a faster recovery in the turbulent wake, which agrees with experiments.
Modeling Oilfield Emulsions: Comparison of Cyclopentane Hydrate and Ice

A comparison of cyclopentane hydrate- and ice-forming emulsions is reported. Density-matched 40% (v/v) water emulsions are studied at various salt concentrations, using experimental tools of rheometry and direct visualization of the morphology under formation of hydrate or ice from the liquid water. Viscosity and yield stress were measured at similar subcoolings (temperature differential between dissociation or melting temperature and the system temperature, with the latter lower) and water conversions, which was controlled by the initial salt concentration in the aqueous phase of the emulsions at a fixed temperature. Large differences in viscosity and yield stress of the final structure were observed between the hydrate- and ice-forming emulsions. At water conversions of Xw = 58%–81%, the ratio of final relative viscosity (final slurry viscosity, relative to the continuous phase viscosity) of hydrate- to ice-forming emulsions is given as ηrel-hyd/ηrel-ice = O(102); at complete water conversion (Xw = 100%...
MaizeGDB - Past, Present, and Future

The Maize Database turns twenty this year. Many of us trace our academic roots back to Emerson: we can do likewise for MaizeGDB.
The Strategy Selection Chart

How to stimulate or expand selective demand and establish product distinctiveness is a major concern of most marketers today. The Strategy Selection Chart provides a tentative solution to this prob...
Cutting Corners: Provider Perceptions of Interpretation Services and Factors Related to Use of an Ad Hoc Interpreter

Introduction:This study assessed health providers’ perceptions of factors related to professional interpretation services and the association between these factors and the potential use of ad hoc i...
Sunshine Act: shedding light on inaccurate disclosures at a gynecologic annual meeting

Background Physicians and hospital systems often have relationships with biomedical manufacturers to develop new ideas, products, and further education. Because this relationship can influence medical research and practice, reporting disclosures are necessary to reveal any potential bias and inform consumers. The Sunshine Act was created to develop a new reporting system of these financial relationships called the Open Payments database. Currently all disclosures submitted with research to scientific meetings are at the discretion of the physician. We hypothesized that financial relationships between authors and the medical industry are underreported. Objectives We aimed to describe concordance between physicians' financial disclosures listed in the abstract book from the 41st annual scientific meeting of the Society of Gynecologic Surgeons to physician payments reported to the Center for Medicaid and Medicare Services Open Payments database for the same year. Study Design Authors and scientific committee members responsible for the content of the 41st annual scientific meeting of the Society of Gynecologic Surgeons were identified from the published abstract book; each abstract listed disclosures for each author. Abstract disclosures were compared with the transactions recorded on the Center for Medicaid and Medicare Services Open Payments database for concordance. Two authors reviewed each nondisclosed Center for Medicaid and Medicare Services listing to determine the relatedness between the company listed on the Center for Medicaid and Medicare Services and abstract content. Results Abstracts and disclosures of 335 physicians meeting inclusion criteria were reviewed. A total of 209 of 335 physicians (62%) had transactions reported in the Center for Medicaid and Medicare Services, which totaled $1.99 million. Twenty-four of 335 physicians (7%) listed companies with their abstracts; 5 of those 24 physicians were concordant with the Center for Medicaid and Medicare Services. The total amount of all nondisclosed transactions was $1.3 million. Transactions reported in the Center for Medicaid and Medicare Services associated with a single physician ranged from $11.72 to $405,903.36. Of the 209 physicians with Center for Medicaid and Medicare Services transactions that were not disclosed, the majority (68%) had at least 1 company listed in the Center for Medicaid and Medicare Services that was determined after review to be related to the subject of their abstract. Conclusion Voluntary disclosure of financial relationships was poor, and the majority of unlisted disclosures in the abstract book were companies related to the scientific content of the abstract. Better transparency is needed by physicians responsible for the content presented at gynecological scientific meetings.
Sampling Properties of Spectral Estimates, Experimental Design, and Spectral Computations

This chapter discusses the practical aspects of spectral analysis. Expressions for the mean, variance, and covariance of spectral estimators are presented in the chapter to discuss the dependence of the bias and variability of these estimators on parameters, such as the number of data points and the equivalent bandwidth. This allows one to discuss the criteria for the selection of spectral windows. In some instances, the time series analyst is surprised by being consulted about the measurement of a spectrum before the data is gathered. This makes it possible to select the appropriate sample size and, in the case of a continuous-time series, the sampling rate, to produce spectral estimates with preselected attributes. The chapter also discusses the guidelines for experimental design that have been most useful in practice. Moreover, the chapter also discusses the methods for computing spectral estimators.
On-line fault diagnosis of electric machine based on the Hidden Markov Model

Extensive work has been presented in the literature related to fault diagnosis and prognosis of machines and related components. With machine learning and statistics applied, methods are proposed in a novel perspective. In this work, the statistics model based on Hidden Markov Model(HMM) is selected because of its wide and strong applications on fault diagnostics in the industry. Based on this method, with the model well-trained, it can encompass the traditional difficulties such as building an exact mathematical model or complex parameters estimation. As the machine fault progresses, the fault features are projected on a certain class and therefore the fault and its severity are identified. Its theoretical base and practical performance are presented and its strength on fault tolerant operation are further come up with.
Surgical Site Infections in Cancer Patients with Intrathecal Drug Delivery Devices.

Objectives Our purpose was to determine the incidence of surgical site infection (SSI) in cancer patients receiving an intrathecal drug delivery system (IDDS) and compare that rate with the incidence of SSI in the general population receiving an IDDS or spinal cord stimulator. We attempted to describe risk factors for SSIs in cancer patients treated with IDDS in terms of exposure to cancer treatments. Design Retrospective review. Setting Large tertiary care center. Patients Cancer patients receiving an IDDS in 2006-2013. Methods The incidence of SSI was determined according to the US Centers for Disease Control and Prevention definition. Medication regimens and current cancer treatment were investigated to identify immunocompromised patients during IDDS placement. Microbacteriology, treatment, and overall outcomes were investigated. Results Sixty-four patients had an IDDS implanted in 2006-2013. SSI developed in four patients (6.2%). All four patients had received chemotherapy or radiotherapy within three months before implantation. Three of the three were receiving dexamethasone, and three of the four required explantation of the IDDS. Conclusion The incidence of SSI was at the upper end of the published infection rates for IDDS. The risk of SSI may be increased in this population because of factors that alter the patient's immune status, including concomitant corticosteroid use, radiotherapy near the SSI, and presence of immunomodulators. The identification and mitigation of certain risk factors for this population may prevent infection in future patients.
Alveolar nonselective channels are ASIC1a/α-ENaC channels and contribute to AFC.

A thin fluid layer in alveoli is normal and results from a balance of fluid entry and fluid uptake by transepithelial salt and water reabsorption. Conventional wisdom suggests the reabsorption is v...
Inductive perturbation tolerance improvement of hybrid networks using an integrated expert system

The design and integration of an expert system is presented to solve the instability and unreliability problems caused by exogenous perturbations in hybrid networks. The proposed expert system performs a directional induction technique on the state vectors of the storage units and linearizes the non-linear dynamics on input and link voltages and currents based on the frequency of dispatch, state of charge, depth of discharge, and utilization factors of storage units. The expert system then identifies optimal, real-time control action on the power variables of the storage units that satisfies various performance and reliability targets. Results show that the expert system based inductive perturbation tolerance approach could provide improvements leading to an optimal performance improvement and enables the hybrid network to satisfy system reliability criteria by compensating for dynamic and transient disturbances as compared to other static and dynamic approaches such as heuristic-based, fitness-based or prediction-based techniques.
To Claim Growth Turf, mTOR Says SOD Off.

Maintaining redox balance in cancer cells is essential for tumor development and progression. In this issue of Molecular Cell, Tsang et al. (2018) identify an evolutionarily conserved mTORC1-dependent mechanism by which cancer cells control redox homeostasis in ischemic tumor microenvironment.
Case Studies in Electrolyte and Acid–Base Disorders

Acid–base and electrolyte cases can be intimidating, for both medical trainees and experienced clinicians. The underlying physiological principles can be difficult to grasp, diagnostic workup elusive, and management options obscure. This chapter includes ten real-life clinical vignettes that provide a step-by-step analysis of the pathophysiology, differential diagnosis, and management of selected clinical problems.
Geometrical Structures in Normal Forms

After a system has been placed into normal form, an immediate question arises: What does the normal form tell us about the dynamics of the system? Sometimes the normalized system is simple enough to be integrable (“by quadrature,” that is, its solution can be reduced to the evaluation of integrals), but this is not the usual case (except in two dimensions). We approach this question in Section 5.1 by establishing the existence of geometrical structures, such as invariant manifolds and preserved foliations, for systems in truncated normal form (that is, polynomial vector fields that are entirely in normal form, with no nonnormalized terms). These geometrical structures explain why some truncated normal forms are integrable, and give partial information about the behavior of others. In particular, the computation of a normal form up to degree k simultaneously computes the stable, unstable, and center manifolds, the center manifold reduction of the system, the stable and unstable fibrations over the center manifold, and various preserved foliations. These concepts will be defined (to the extent that they are needed) when they arise, but the reader is expected to have some familiarity with them. We do not prove the existence of these structures, except in the special case of truncated systems in normal form, where each structure mentioned above takes a simple linear form. For the full (untruncated) systems the relevant existence theorems will be stated without proof, and the normal form will be used to compute approximations.
Family-Supportive Supervisory Behaviors as a Moderator of the Relationship between Job Strain and Workers' Blood Pressure

i List of Tables iv List of Figures v Chapter I: Introduction 1 Chapter II: Stress 5 Chapter III: Job Demands and Control 8 Chapter IV: Measures of Blood Pressure 18 Chapter V: Family-Supportive Supervisory Behaviors 31 Chapter VI: Present Study 38 Chapter VII: Method 41 Chapter VIII: Results 53 Chapter IX: Discussion 71 Tables 85 Figures 96 References 100 Appendix A: Job Content Questionnaire 113
Community Mental Health Center Integrated Care Outcomes.

Despite the compelling logic for integrating care for people with serious mental illness, there is also need for quantitative evidence of results. This retrospective analysis used 2013–2015 data from seven community mental health centers to measure clinical processes and health outcomes for patients receiving integrated primary care (n = 18,505), as well as hospital use for the 3943 patients with hospitalizations during the study period. Bivariate and regression analyses tested associations between integrated care and preventive screening rates, hemoglobin A1c levels, and hospital use. Screening rates for body-mass index, blood pressure, smoking, and hemoglobin A1c all increased very substantially during integrated care. More than half of patients with baseline hypertension had this controlled within 90 days of beginning integrated care. Among patients hospitalized at any point during the study period, the probability of hospitalization in the first year of integrated care decreased by 18 percentage points, after controlling for other factors such as patient severity, insurance status, and demographics (p < .001). The average length of stay was also 32% shorter compared to the year prior to integrated care (p < .001). Savings due to reduced hospitalization frequency alone exceeded $1000 per patient. Data limitations restricted this study to a pre−/post-study design. However, the magnitude and consistency of findings across different outcomes suggest that for people with serious mental illness, integrated care can make a significant difference in rates of preventive care, health, and cost-related outcomes.
Differences in Active Defense Responses of Two Gossypium barbadense L. Cultivars Resistant to Fusarium oxysporum f. sp. vasinfectum Race 4.

A highly virulent race 4 genotype of Fusarium oxysporum f. sp. vasinfectum (Fov) was identified for the first time in the western hemisphere in 2002 in cotton fields in the San Joaquin Valley of Ca...
Mitos y falsedades sobre el realismo científico

Selective realist projects seek to strengthen scientific realism, but influential reactions (from anti-realist as well as realist camps) regard selectivist achievements as problematic and misguided developments, because -the story goes- those developments disfigure and devalue realism, transforming it into a position that is not worth taking into account. An examination of the charges formulated against selective realism and their respective historical background suggests, however, that the charges in question rest in myths and falsehoods about the character of realist positions; if so, the charges fail.
Commentary 2 on Problem Solving for the 21st Century

Discussing problem solving for this century is a daunting task—a real “problem.” English and Sriraman present a look at the past research on mathematical problem solving and its impact on the curriculum. They identify several limiting factors affecting problem-solving research and propose ideas to advance this research.
Is Verstehen Scientific Understanding

Many have argued that the human sciences feature a unique form of understanding (Verstehen) that is absent from the natural sciences. However, in the last decade or so, epistemologists and philosophers of natural science have been proffering analyses of a kind of natural-scientific understanding. Using examples from educational psychology and anthropology, I argue that there are prima facie reasons to think these recent accounts of natural-scientific understanding impose necessary conditions on Verstehen. This suggests that any claim about Verstehen’s distinctiveness faces hitherto-unappreciated burdens of proof.
Observational Studies of PFO Closure for Stroke

Abstract Patent foramen ovale (PFO) is prevalent among 25% of all adults. Observational studies have shown that nearly half of patients with cryptogenic stroke are found to have a PFO during the stroke work-up, likely due to paradoxical thromboembolism. There is a wealth of observational data that have evaluated the safety and efficacy of transcatheter closure of PFO in select patients. These reports have described experience with many generations of a variety of devices across several centers worldwide. In addition, there have been a few systematic reviews and meta-analyses of these observational studies that have summarized the experience of transcatheter PFO closure in comparison to standard of care medical therapy. Such reports have formed the basis for the conduct of pivotal randomized controlled trials that have attempted to definitively determine the efficacy and safety of PFO closure versus medical therapy for secondary prevention of stroke presumed to be from paradoxical thromboembolism. This chapter will describe the key observational studies of PFO closure for stroke, as well as the meta-analyses of these studies that provided early insight to the role of percutaneous PFO device closure for secondary stroke prevention.
Carbon nanotube fibers spun directly from furnace

Abstract Carbon nanotube (CNT) is a promising engineering material based on its superior properties. CNT fibers can be produced directly from a high-temperature furnace, which provides an effective method for scaling up the fiber production. In this process, nanoscale CNTs are assembled into macroscale entities, which are then spun into fibers continuously in one step. The properties of the final CNT fiber depend on both the nanotube quality and the assembly morphology. In this chapter, the floating catalyst synthesis method is discussed, along with the spinning process and properties of the resulting CNT fibers.
Menagerie: A text-mining tool to support animal-human translation in neurodegeneration research.

Discovery studies in animals constitute a cornerstone of biomedical research, but suffer from lack of generalizability to human populations. We propose that large-scale interrogation of these data could reveal patterns of animal use that could narrow the translational divide. We describe a text-mining approach that extracts translationally useful data from PubMed abstracts. These comprise six modules: species, model, genes, interventions/disease modifiers, overall outcome and functional outcome measures. Existing National Library of Medicine natural language processing tools (SemRep, GNormPlus and the Chemical annotator) underpin the program and are further augmented by various rules, term lists, and machine learning models. Evaluation of the program using a 98-abstract test set achieved F1 scores ranging from 0.75–0.95 across all modules, and exceeded F1 scores obtained from comparable baseline programs. Next, the program was applied to a larger 14,481 abstract data set (2008–2017). Expected and previously identified patterns of species and model use for the field were obtained. As previously noted, the majority of studies reported promising outcomes. Longitudinal patterns of intervention type or gene mentions were demonstrated, and patterns of animal model use characteristic of the Parkinson’s disease field were confirmed. The primary function of the program is to overcome low external validity of animal model systems by aggregating evidence across a diversity of models that capture different aspects of a multifaceted cellular process. Some aspects of the tool are generalizable, whereas others are field-specific. In the initial version presented here, we demonstrate proof of concept within a single disease area, Parkinson’s disease. However, the program can be expanded in modular fashion to support a wider range of neurodegenerative diseases.
Autologous Fat Grafting

Volume loss in the face is a key component of facial aging. Autologous volume restoration using fat to fill and lift the tissues has been a successful procedure used to minimize the signs of aging or to enhance facial features and maintain signs of youth.
CODE KOUNIS: A CASE OF CORONARY ARTERY VASOSPASM SECONDARY TO CONTRAST

Anaphylaxis is a life-threatening reaction mediated by IgE and characterized by the release of mast cells and histamine. Histamine is a well-established stimulus for coronary artery vasospasm. There is a rare phenomenon, first described in 1991 by Dr. Kounis as “allergic angina,” in which this
Epilepsy Lesion Localization is not Predicted by Developmental Venous Anomaly Location or its FDG‐PET Metabolic Activity

Background and purpose This study's purpose is to correlate location and metabolic activity of developmental venous anomalies (DVAs) in epilepsy patients to the seizure focus as determined by ictal/interictal encephaloelectrogram (EEG). Methods A retrospective search was performed for epilepsy patients with DVAs who underwent brain 18 F-fluorodeoxyglucose positron emission tomography (18 F-FDG-PET) and magnetic resonance imaging (MRI). MRI exams were analyzed to characterize DVA location and associated structural findings. MRI and PET images were co-registered and assessment of 18 F-FDG uptake in the DVA territory was performed. The electronic medical record was reviewed for each subject to determine seizure semiology and site of seizure focus by ictal/interictal EEG. Results Twenty-eight DVAs in 25 patients were included. Twelve DVAs demonstrated regional metabolic abnormality on 18 F-FDG-PET. There was no significant correlation between DVA site and seizure focus on EEG. DVA location was concordant with EEG seizure focus in three subjects, and all three demonstrated hypometabolism on 18 F-FDG-PET. This significance remains indeterminate, as one of these DVAs was associated with cavernoma, which could serve as the true seizure focus, and one of the patients underwent resection of the DVA without decrease in seizure frequency. Furthermore, there was no statistically significant relationship between DVA metabolic activity and DVA-EEG lobar or laterality concordance. Conclusions In this sample, there is no significant correlation between location of DVA and seizure focus, and hypometabolism within the DVA territory is not predictive of EEG/DVA co-localization. As use of 18 F-FDG-PET for evaluation of epilepsy increases, knowledge of this poor correlation is important to avoid diagnostic confusion and potentially unnecessary surgery in epilepsy patients.
Mcdonald and Siegel Meet Laibson: Dynamic Investment Strategies with Time-Inconsistent Preferences

The real options framework has been used extensively to analyze the timing of investment under uncertainty. The ability to defer decisions under evolving uncertainty provides the investor with a valuable option to wait. While real options models assume that agents possess a constant rate of time preference, there is substantial evidence that decision makers are very impatient about choices in the short-term, but are quite patient when choosing between long-term alternatives. We extend the real options framework to model the investment timing decisions of entrepreneurs with such time-inconsistent preferences. Two opposing forces determine investment timing: while evolving uncertainty induces investors to defer investment in order to take advantage of the option to wait, their present-biased preferences motivates them to invest earlier in order to avoid the time-inconsistent behavior they will display in the future. We find that the precise trade-off between these two forces depends on such factors as whether investors are sophisticated or naive about their future time-inconsistent behavior, as well as whether the payoff from investment occurs all at once or over time. We extend the model to consider equilibrium investment behavior for an industry comprised of time-inconsistent entrepreneurs. Equilibrium involves the dual problem of agents playing dynamic games against others as well as against their own future selves.
Dissemination of Information About Climate Change by State and Local Public Health Departments: United States, 2019–2020

Objectives. To determine if and how state and local public health departments present information about climate change on their Web sites, their most public-facing platform.Methods. We collected da...
Multimodal pedagogy in TESOL teacher education: Students’ perspectives

Abstract Despite the increasing incorporation of multimodal practices into ESL/EFL classes, research on multimodal pedagogy in TESOL teacher education is still in its infancy. Empirical evidence also shows that ESL/EFL teachers lack skills to design and deliver multimodal practices. To bridge the research gap and innovate the TESOL curriculum, the author in this study implemented multimodal projects in two online graduate courses, and examined the students’ (pre-/in-service teachers’) perceptions on integration of multimodal projects. The analyses of semi-structured interviews and written narratives, supplemented with the multimodal products, revealed that the multimodal practices facilitated the students’ learning of content knowledge and their professional development. The perceived benefits included engaging and motivating content learning, retaining and deepening knowledge, fostering mutual learning in online community, enhancing digital learning, and fostering motivation to implement multimodal pedagogy. The students also conveyed challenges in topic selection, technology use, and time control, and provided suggestions on peer interaction, technology training, and task management. This study has significant implications for research and pedagogy in TESOL teacher education.
Dendritic and Seaweed Growth of Proeutectic Scandium Tri-Aluminide in Hypereutectic Al-Sc Undercooled Melt

Abstract The morphologies of proeutectic Al3Sc growing in an undercooled hypereutectic Al-2 wt.% Sc alloy melt with varied cooling rates were carefully examined under electron microscopes, in order to reveal its different growth mechanisms. At a low cooling rate (~1 K·s − 1), as expected, the formation of proeutectic Al3Sc was governed by the lateral growth, exposing six flat {100} facets. At an intermediate cooling rate (~400 K·s − 1), proeutectic Al3Sc grew in a dendritic manner, with well-defined backbones extending in its eight 〈111〉 directions and paraboloidal dendrite tips, although the dendrite tips and side-branches turned into faceted steps at a late growth stage, when the lateral growth prevailed again. At a high cooling rate (~1000 K·s − 1), proeutectic Al3Sc primarily solidified into an entirely seaweed particle, which was composed of interior compact seaweeds and exterior fractal seaweeds. The detailed formation mechanisms of the proeutectic Al3Sc in the latter two situations, to the author's knowledge, are first clarified with growth models in the present work. Various morphological stability criteria were used to verify the proposed dendritic and seaweed growth models, by examining characteristic length scales in the structure, such as the radius of the dendrite tip, the interspacing between seaweed branches, and the size of destabilized sphere at an early growth stage.
Dance on the Brain: Enhancing Intra and Inter-Brain Synchrony

Dance has traditionally been viewed from a Eurocentric perspective as a mode of self-expression that involves the human body moving through space, performed for the purposes of art, and viewed by an audience. In this Hypothesis and Theory article, we synthesize findings from anthropology, sociology, psychology, dance pedagogy, and neuroscience to propose The Synchronicity Hypothesis of Dance, which states that humans dance to enhance both intra- and inter-brain synchrony. We outline a neurocentric definition of dance, which suggests that dance involves neurobehavioral processes in seven distinct areas including sensory, motor, cognitive, social, emotional, rhythmic, and creative. We explore The Synchronicity Hypothesis of Dance through several avenues. First, we examine evolutionary theories of dance, which suggest that dance drives interpersonal coordination. Second, we examine fundamental movement patterns, which emerge throughout development and are omnipresent across cultures of the world. Third, we examine how each of the seven neurobehaviors increases intra- and inter-brain synchrony. Fourth, we examine the neuroimaging literature on dance to identify the brain regions most involved in and affected by dance. The findings presented here support our hypothesis that we engage in dance for the purpose of intrinsic reward, which as a result of dance-induced increases in neural synchrony, leads to enhanced interpersonal coordination. This hypothesis suggests that dance may be helpful to repattern oscillatory activity, leading to clinical improvements in autism spectrum disorder and other disorders with oscillatory activity impairments. Finally, we offer suggestions for future directions and discuss the idea that our consciousness can be redefined not just as an individual process but as a shared experience that we can positively influence by dancing together.
Understanding ‘faith’ in faith-based organizations: refugee resettlement work as religious practice

The Trump administration has consistently opposed refugee resettlement, slashing national admission ceilings and undermining the long-running U.S. resettlement programme. While these changes have b...
The Effects of Language Barriers and Time Constraints on Online Learning Performance: An Eye-Tracking Study.

ObjectiveThe goal of this study is to model the effect of language use and time pressure on English as a first language (EFL) and English as a second language (ESL) students by measuring their eye ...
Valence Photoionization and Autoionization of the Formyl Radical.

We have used 308 nm photolysis of acetaldehyde to measure a photoionization spectrum of the formyl (HCO) radical between 8 and 11.5 eV using an 11 meV FWHM photoionization energy resolution. We have confirmed that the formyl radical is the carrier of the spectrum by generating an identical spectrum of the HCO product in the Cl + H2CO reaction. The spectrum of HCO and its deuterated isotopologue (DCO) have several resolved autoionizing resonances above the Franck-Condon envelope, which we assign to autoionization after initial excitation into neutral 3sσ and 3p Rydberg states converging to the first triplet excited state of HCO+(a 3A'). The quantum defects for these states are δ3sσ = 1.06 ± 0.02 and δ3p = 0.821 ± 0.019. We report absolute photoionization cross-section measurements of σHCOPI(9.907 eV) = 4.5 ± 0.9 Mb, σHCOPI(10.007 eV) = 4.8 ± 1.0 Mb, σHCOPI(10.107 eV) = 6.0 ± 1.2 Mb, σHCOPI(10.107 eV) = 5.7 ± 1.2 Mb, and σHCOPI(10.304 eV) = 10.6 ± 2.2 Mb relative to the photoionization cross section of the methyl radical. The absolute cross-section measurements are a factor of ∼1.5 larger than those determined in past studies, although the presence of strong autoionizing features supports a dependence on photoionization energy resolution. We propose that the semiempirical model of Xu and Pratt for estimation of free radical photoionization cross sections is more accurate when applied with a reference species containing the same atoms as the free radical rather than isoelectronic species with different atoms.
Adapting Recruitment of College Students for the Snackability Trial During COVID-19 in the U.S.

Objectives With COVID-19 pandemic, the recruitment of participants for research had to adapt to new formats. The objective of this analysis was to describe the different recruitment methods of college students for the Snackability Trial during COVID-19. We also examined the reasons for exclusion in the study. The Snackability Trial is a randomized controlled trial to test the Snackability mobile app designed and developed at FIU to help students identify healthy snacks by providing a score from 0–11 (the higher the score, the healthier the snack) based on the USDA snack guidelines.
Increasing Use of Neoadjuvant Treatment for T1 and T2 HER2-Positive Tumors

Use of targeted therapy for human epidermal growth factor receptor-2 (HER2)-positive breast cancer has led to improvements in survival. Furthermore, neoadjuvant chemotherapy (NAC) with dual HER2 agents demonstrated improved pathological complete response (pCR) rates. With these data, and with US FDA approval in September 2013 of pertuzumab in the neoadjuvant setting, we hypothesized that the use of NAC for early-stage HER2-positive patients is increasing. With Institutional Review Board approval, we reviewed 267 patients with 268 clinical T1 and T2 HER2-positive tumors treated from October 2008 to September 2014. We compared treatment in the early (October 2008–September 2013) to recent (October 2013–September 2014) periods. Statistical analysis was performed using Chi square tests. Mean patient age was 59 years. Clinical T stage included 6 (2 %) T1mic, 11 (4 %) T1a, 41 (15 %) T1b, 95 (35 %) T1c, and 115 (43 %) T2. Targeted therapy included combinations of trastuzumab, lapatinib, pertuzumab, and neratinib. NAC use increased from 53/219 (24.2 %) in the early group to 19/49 (38.8 %) in the recent group (p = 0.04). Forty-two percent (8/19) of patients in the recent group received neoadjuvant pertuzumab versus 0/53 in the early group (p < 0.0001). More clinically node-negative (cN0) patients received NAC in the recent (12/41, 29.3 %) versus early (20/167, 12.0 %) period (p = 0.01). For T1 tumors, the use of NAC more than doubled between the two time periods (5.6–17.2 %; p = 0.06), while NAC use increased from 48 to 70 % for T2 tumors (p = 0.08). The overall pCR rate after NAC was 48.6 % (35/72). NAC for HER2-positive breast cancer patients is increasing. Most striking was a substantial increase in NAC for patients with T1 tumors and cN0 disease.
Reporting small bowel dose in cervix cancer high-dose-rate brachytherapy

Abstract Small bowel (SB) is an organ at risk (OAR) that may potentially develop toxicity after radiotherapy for cervix cancer. However, its dose from brachytherapy (BT) is not systematically reported as in other OARs, even with image-guided brachytherapy (IGBT). This study aims to introduce consideration of quantified objectives for SB in BT plan optimization and to evaluate the feasibility of sparing SB while maintaining adequate target coverage. In all, 13 patients were included in this retrospective study. All patients were treated with external beam radiotherapy (EBRT) 45 Gy in 25 fractions followed by high dose rate (HDR)-BT boost of 28 Gy in 4 fractions using tandem/ring applicator. Magnetic resonance imaging (MRI) and computed tomographic (CT) images were obtained to define the gross tumor volume (GTV), high-risk clinical target volume (HR-CTV) and OARs (rectum, bladder, sigmoid colon, and SB). Treatment plans were generated for each patient using GEC-ESTRO recommendations based on the first CT/MRI. Treatment plans were revised to reduce SB dose when the D 2 cm 3 dose to SB was > 5 Gy, while maintaining other OAR constraints. For the 7 patients with 2 sets of CT and MRI studies, the interfraction variation of the most exposed SB was analyzed. Plan revisions were done in 6 of 13 cases owing to high D 2 cm 3 of SB. An average reduction of 19% in D 2 cm 3 was achieved. Meeting SB and other OAR constraints resulted in less than optimal target coverage in 2 patients (D90 of HR-CTV
Quality of Writing by Elementary Students With Learning Disabilities

AbstractTeaching students with learning disabilities to write often presents great challenges. In this article, we describe studies of a HyperCard stack that was developed over a four-year period to assist beginning writers and their teachers. Students enter words from a keyboard or by selecting from prepared lists (a 1,000 word core list; four teacher-generated lists; a first names list; and a user-generated, private list). All text can be spoken using a speech synthesis system (robotic voice). Records of students’ writing are created automatically. Student’s “certificates” with writing samples and pictures, together with teacher feedback, may be printed. ROBO-Writer was compared with paper-and-pencil writing and a commonly used word processing application for groups of students with learning disabilities at two school sites. Using four rating criteria, texts created by students with learning disabilities who used ROBO-Writer showed significantly higher scores than did those of matched students using oth...
Effective nucleon-nucleon cross sections in symmetric and asymmetric nuclear matter

We calculate nucleon-nucleon cross sections in the nuclear medium with unequal densities of protons and neutrons. We use the Dirac-Brueckner-Hartree-Fock approach together with realistic nucleon-nucleon potentials. We examine the effect of asymmetry in neutron and proton concentrations and find that it can be significant for scattering of identical nucleons. Numerical results are included for potential applications in transport equations.
Recovering Implicit Thread Structure in Newsgroup Style Conversations.

On-line discussions are composed of multiple inter-woven threads, regardless of whether that threaded structure is made explicit in the representation and presentation of the conversational data. Recovering the thread structure is valuable since it makes it possible to isolate discussion related to specific subtopics or related to particular conversational goals. In prior work, thread structure has been reconstructed using explicit meta-data features such as “posted by” and “reply to” relationships. The contribution of this paper is a novel approach to recovering thread structure in discussion forums where this explicit meta-data is missing. This approach uses a graph-based representation of a collection of messages where connections between messages are postulated based on inter-message similarity. We evaluate three variations of this simple baseline approach that exploit in different ways the temporal relationships between messages. The results show that the three proposed approaches outperform the simple thresholdcut baseline.
Multi-scale "spatial" analysis of computer network traffic data

Summary form only given. Many key tasks in computer network monitoring, such as load balancing and the detection of anomalies (e.g., DoS attacks, link failures, and routing loops), fundamentally require a whole-network perspective - that is, methods of 'spatial' traffic analysis. A key challenge to advances in this area is posed by the fact that the 'space' in question, deriving from a network, is not some Euclidean sub-space but rather a graph. We focus on the problem of developing analyses sensitive to 'spatial' scale and introduce a framework for graph-based wavelets. In conjunction, we also consider the important issue of characterizing the underlying 'spatial' auto-correlation structure.
Stability and Change

SUMMARY The author maintains the idea that the process of marital therapy must attend to stability (morphostasis) and change (morphogenesis) from both systemic-interpersonal and intrapersonal perspectives and argues from an attachment theory perspective that creating a secure base can provide the stability essential for allowing couples to identify, understand, and manage their experience of anxiety in creating therapeutic change.
Bioavailability of Different Sources of Dietary Iron Fed to Pitman-Moore Miniature Pigs

Prevention of Fe deficiency was studied with eight Pitman-Moore miniature pigs in each of seven groups. From 5 to 33 days of age the animals received identical cereal-milk diets except for Fe content: diet 1, no added Fe (8 ppm); diet 2, ferrous sulfate; diet 3, catalytically reduced Fe; diet 4, electrolytic Fe powder; diet 5, sodium Fe pyrophosphate; diet 6, ferripolyphosphate powder; diet 7, disodium Fe EDTA. Diets 2-7 provided 64 to 69 ppm of supplemental Fe. Body weight and gain in weight of pigs fed diet 1 did not differ significantly from those of pigs fed diets 2-7; however, gain in body weight between 21 and 28 days of the feeding trial was sig nificantly less in pigs fed diets 1 or 5 than in pigs fed diets 2, 6 or 7. Final Hb and hematocrit values were less than initial values in pigs fed diets 1, 3, 4 and 5. The change in Hb, hematocrit and total Hb Fe of pigs fed diets 1, 3 or 5 differed significantly from those of pigs fed diets 2, 6 or 7. The efficiency with which supplemental Fe was incorporated into Hb ranged between 27 and 30% in pigs fed diets 2, 6 or 7, was 21% in pigs fed diet 4 and approximately 10% in pigs fed diets 3 or 5. Pigs fed diet 1 differed from those fed the other diets in the following manner: liver weight was sig nificantly less; weights of spleen, heart and kidney were significantly greater; less of an intraperitoneal injection of Te was retained in Hb and in organs; of the retained Te, significantly less was found in Hb and significantly more in tissues. Fe status as mea sured by Hb and hematocrit appeared to be inversely correlated with Te concentration in liver, spleen, kidney and heart. J. Nutr. 104: 619-628, 1974.
Guilt and Mental health

Publisher Summary Guilt plays a prominent role in cognitive theories of mental illness as well. Guilt has been associated with a number of internalizing disorders, but most frequently with depression. When guilt is chronic, it becomes closely linked with symptoms of mental illness. Perhaps the most important implication of the present work is the importance of alleviating guilt constructively and effectively. Lewis suggests that reaction formation or sublimation might be therapeutic for the individual experiencing chronic guilt. Even if the other person is dead, the guilty individual might provide indirect reparation by giving to charity in memory or honor of the deceased or by providing social or financial support to the deceased person's family. Religious confession and penance, participation in Yom Kippur services, and ministerial or rabbinical counseling may all help alleviate chronic guilt. Chronic guilt from day-to-day hassles may be lessened by participating in amnesty days for overdue library books or delinquent tickets. Individuals might be encouraged to seek forgiveness for transgressions they have committed even when these lapses occurred long ago. Indeed, if guilt feelings are still operative years later, this may provide all the more reason for individuals to work to resolve them.
Mutations that alter the signal sequence of alkaline phosphatase in Escherichia coli.

A phoA-lacZ gene fusion was used to isolate mutants altered in the alkaline phosphatase signal sequence. This was done by selecting Lac+ mutants from a phoA-lacZ fusion strain that produces a membrane-bound hybrid protein and is unable to grow on lactose. Two such mutant derivatives were characterized. The mutations lie within the phoA portion of the fused gene and cause internalization of the hybrid protein. When the mutations were genetically recombined into an otherwise wild-type phoA gene, they interfered with export of alkaline phosphatase to the periplasm. The mutant alkaline phosphatase protein was found instead in the cytoplasm in precursor form. DNA sequence analysis demonstrated that both mutations lead to amino acid alterations in the signal sequence of alkaline phosphatase. Images
Storytelling and self‐confrontation: Parables as communication strategies

Speakers in many religious traditions have often told parables to arouse listeners to confront their own thoughts, feelings, attitudes, and actions. Because these stories serve both therapeutic and epistemic functions, their study has important implications for the development of rhetorical theory. This essay analyzes parables to explore the rhetorical significance of narration as a form of discourse and as an act of relational communication.
A CONVENIENT SYNTHESIS OF (-)-METHYL EPIJASMONATE

Abstract A short, enantioselective synthesis of (-)-methyl epi-jasmonate, ent-1, has been achieved starting from readily available Corey lactone aldehyde 9. The key features include the stereoselective installation of 2,3-cis-disubstituted side-chains by hydrogenation of dienoate 8 and subsequent one-carbon degradation.