cssi/SciSciGPT-SciSciNet huggingface dataset:
Liquid hydrogen sensor considerations for space exploration

The on-orbit management of liquid hydrogen planned for the return to the moon will introduce new considerations not encountered in previous missions. This paper identifies critical liquid hydrogen sensing needs from the perspective of reliable on-orbit cryogenic fluid management, and contrasts the fundamental differences in fluid and thermodynamic behavior for ground-based versus on-orbit conditions. Opportunities for advanced sensor development and implementation are explored in the context of critical Exploration Architecture operations such as on-orbit storage, docking, and trans-lunar injection burn. Key sensing needs relative to these operations are also examined, including: liquid/vapor detection, thermodynamic condition monitoring, mass gauging, and leak detection. Finally, operational aspects of an integrated system health management approach are discussed to highlight the potential impact on mission success.
Simulation of ductile crack growth using computational cells: numerical aspects

This study explores key computational issues that aAect analyses employing the computational cell methodology to predict crack growth in ductile metals caused by void growth and coalescence. These issues — computational load step size, procedures to remove cells with high porosity from the analysis, and the porosity for cell deletion — can adversely aAect predicted crack growth resistance (R) curves and/or hinder convergence of both local constitutive and global iterative computations. Strain increments generated by large computational load steps introduce errors in the predicted peak stress of computational cells and prevent convergence of stress updates for the Gurson‐Tvergaard constitutive model. An adaptive load control algorithm, which limits the maximum porosity over a load step, eliminates this problem. The delayed release of remaining forces in newly deleted cells elements elevates the stress triaxiality and thus artificially accelerates the rate of crack extension. The release of cell forces using a traction-separation model minimizes this eAect while maintaining good numerical convergence of the solutions. Crack growth analyses for a moderate strength steel demonstrate that critical porosity valuesOfEU between 0.1 and 0.2 show almost no eAect on predicted R-curves, while both larger and smaller values lead to low J‐Da curves. Finally, a parametric study indicates that specimens of low-hardening materials and specimens with high crack-front constraint show a stronger influence of large computational load steps and the delayed release of cell forces. Use of the adaptive load control algorithm and the traction-separation model with the controlling parameters described here, minimize numerical eAects on predicted R-curves. 7 2000 Elsevier Science Ltd. All rights reserved.
Political versus epidemiological correctness.

In the March issue of the journal, the Joint SHEA and APIC Task Force indicates that the Society for Healthcare Epidemiology of America (SHEA) and the Association for Professionals in Infection Control and Epidemiology (APIC) support the use of active detection and isolation (ADI) for controlling nosocomial infections due to methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) “in appropriate circumstances, as recommended in previously published guidelines”1(p250) (those published by SHEA and the Healthcare Infection Control Practices Advisory Committee [HICPAC]), but that SHEA and APIC oppose the use of legislation for mandating any infection control approach, including this one as tried in 2006 in Illinois and Maryland. Both supporters and opponents of controlling MRSA and VRE with ADI probably will agree that legislation is not the optimal way to control nosocomial infections in general, but this position statement undoubtedly will please the latter more than it does the former because the SHEA/APIC Task Force argues that ADI is not ready for routine use throughout all healthcare facilities, directly opposing the position of the original SHEA guideline. As an author of that SHEA guideline, I would like to comment. First, the new position seems politically correct (since most infection control professionals have not yet bothered using ADI to control MRSA and VRE), but many of the planks of the SHEA/APIC Task Force position statement are misleading.
Computation of load performance and other parameters of extra high speed modified Lundell alternators from 3D-FE magnetic field solutions

A combined magnetic vector potential, magnetic scalar potential method of computation of 3-D magnetic fields by finite elements, in combination with state modeling in the abc frame of reference, is used for global 3-D magnetic field analysis and machine performance computation under rated load and overload condition in an example 14.3 kVA modified Lundell alternator. The results vividly demonstrate the 3-D nature of the magnetic field in such machines and show how this model can be used as an excellent tool for computation of flux density distributions, armature current and voltage waveform profiles, and harmonic contents, as well as for computation of torque profiles and ripples. Use of the model in gaining insight into locations of regions in the magnetic circuit with heavy degrees of saturation is demonstrated. Experimental results which correlate well with the simulations of the load case are given. >
Effect of Cranial Cruciate Ligament Deficiency, Tibial Plateau Leveling Osteotomy, and Tibial Tuberosity Advancement on Contact Mechanics and Alignment of the Stifle in Flexion

Objective: To assess contact mechanics and 3-dimensional (3-D) joint alignment in cranial cruciate ligament (CCL)-deficient stifles before and after tibial plateau leveling osteotomy (TPLO) and tibial tuberosity advancement (TTA) with the stifle in 90° of flexion. Study Design: In vitro biomechanical study. Sample Population: Cadaveric pelvic limb pairs (n=8) from dogs weighing 28–35 kg. Methods: Contralateral limbs were assigned to receive TPLO or TTA. Digital pressure sensors were used to measure femorotibial contact area, peak and mean contact pressure, and peak pressure location with the limb under a load of 30% body weight and stifle flexion angle of 90°. 3-D poses were obtained using a Microscribe digitizer. Specimens were tested under normal, CCL deficient, and treatment conditions. Results: Significant disturbances in alignment were not observed after CCL transection, although medial contact area was 10% smaller than normal (P=.003). There were no significant differences in contact mechanics or alignment between normal and TTA conditions; TPLO induced 6° varus angulation (P<.001), 26% decrease in lateral peak pressure (P=.027), and 18% increase in medial mean pressure (P=.008) when compared with normal. Conclusion: Cranial tibial subluxation is nominal in CCL-deficient stifles loaded in flexion. Stifle alignment and contact mechanics are not altered by TTA, whereas TPLO causes mild varus and a subsequent increase in medial compartment loading. Clinical Relevance: Cranial tibial subluxation of CCL-deficient stifles may not occur during postures that load the stifle in flexion. The significance of minor changes in loading patterns after TPLO is unknown.
Why and How to Improve Physical Activity Promotion: Lessons from Behavioral Science and Related Fields

This commentary highlights the importance of regular physical activity to the nation's health and discusses some of the major challenges and opportunities currently facing the field.
DO STUDENTS EXPERIENCE FLOW CONDITIONS ONLINE

This study asked graduate students enrolled in higher education programs at two institutions to ascertain whether and to what extent they experienced nine flow-related conditions in two settings: online courses or surfing or gaming online. In both settings, flow was experienced “sometimes,” although no significant difference in mean frequency was found for the two settings. When asked for examples of flow, however, students gave more examples drawn from non-class-related activities (n = 35) than class activities (n = 3), including researching a number of topics related to health, travel, or shopping, or engaging with Facebook. Finally, students found that online class experiences “frequently” impacted their satisfaction with the course and three flow conditions were found to be correlated with course satisfaction at p ≤ 0.05: clear goals, concentration and focus, and a sense of personal control over activity.
Poly(amidoamine) dendrimer-supported organoplatinum antitumour agents

While numerous water-soluble biocompatible polymers have been utilized for the construction of drug conjugates that offer significant advantages for drug delivery, poly(amidoamine) (PAMAM) dendrimers are superior in many ways for this purpose. They display nanoscale size, uniform shape, excellent water solubility, low toxicity and high surface functionality. In an attempt to circumvent the toxic side effects associated with the administration of organoplatinum drugs, a polymeric prodrug has been prepared from the treatment of a generation 4.5 PAMAM dendrimer with diaquo(1,2-diaminocyclohexane)platinum(II). A well-defined dendrimer–platinum conjugate containing 40 (1,2-diaminocyclohexane)platinum(II) units coordinated to the dendrimer surface via carboxylate groups is formed. This adduct is well behaved, water soluble, contains a high loading of platinum moieties and displays sustained release of active platinum species over a 24 h period under physiological conditions.
Foster Caregivers’ Perspectives on the Medical Challenges of Children Placed in Their Care Implications for Pediatricians Caring for Children in Foster Care

Objective. To investigate, using qualitative methodology, foster caregivers’ perspectives related to the medical needs of children placed in their care. Study design. Fifteen foster caregivers were individually interviewed using a semistructured open-ended question guide. Data were coded, and the analysis was conducted in an inductive manner, allowing themes to emerge from the interviews. Results. The following 4 themes were identified: (1) the fragmented histories provided to foster caregivers and difficulty in obtaining information; (2) the unique medical complications that children in foster care experience; (3) the difference between “doing what is expected” and becoming a proactive foster caregiver; and (4) the support needs of foster caregivers. Conclusions. Foster caregivers receive insufficient information despite the evidence that these children are likely to have complex needs. It is, therefore, necessary for the pediatrician to recognize existing medical problems, identify new medical problems,...
The use of environmental assays for impact assessment

The assessment of impacts of chemically contaminated aquatic environments on animal systems has a number of shortcomings. These include problems with analyses for toxic chemicals and the relevance of bioassays for predicting risk to ecosystems. Research is urgently needed to find better ways to solve these problems, particularly with respect to chronic exposures.
Identification of stochastic linear systems via spectral analysis: reduced-order approximation, performance analysis and transfer function bias

Estimation of the parametric input-output (IO) infinite impulse response (IIR) transfer function given time-domain IO data is considered. Some of the desirable properties of any approach to this problem are: unimodality of the performance surface, consistent identification in the sufficient-order case, and stability of the fitted model under undermodeling. Some of the well-known approaches fail to satisfy one or more of these properties. The time-domain equation error method (EEM) yields a unimodal performance surface, biased estimates in colored noise and sufficient-order case, and stable fitted models under undermodeling if the input is autoregressive. In this paper we propose a frequency-domain solution to the least-squares equation error identification problem using the power spectrum and the cross-spectrum of the IO data to estimate the IO parametric transfer function. The proposed approach is shown to yield a unimodal performance surface, consistent identification in colored noise and sufficient-order case, and stable fitted models under undermodeling; for arbitrary stationary inputs so long as they are persistently exciting of sufficiently high order. Asymptotic performance analysis is carried out for both sufficient-order and reduced-order cases. These asymptotic results can then used to derive statistics on the corresponding estimated transfer function. We also investigate an iterative pseudo-maximum likelihood approach and analyse its performance under sufficient-order modeling. Finally a computer simulation example is presented.
What is sublimated in sublimation

Sublimation has always been an elusive idea in psychoanalytic thought. This is because psychoanalysis is most systematic as a clinical psychology, while sublimation signifies an obverse of neurosogenesis. Nevertheless, the idea of sublimation remains a concern of psychoanalysis inasmuch as sublimation entails a version of socialization and cultural experience that answers to various principles of psychoanalytic theory. For reasons developed here, the creation and experience of art figure prominently in reflections on sublimation. Clinical material from the analyses of several artists is presented to demonstrate how neurosis takes a toll of sublimation and how sublimation takes a toll of the analytic process. Sublimatory experiences are then reconstructed from the devices of art. Two achievements of sublimation are especially noted: reduction of the ordinary instrumental functions of affects, and heightened consciousness of endopsychic processes.
Supporting fault tolerance in a data-intensive computing middleware

Over the last 2–3 years, the importance of dataintensive computing has increasingly been recognized, closely coupled with the emergence and popularity of map-reduce for developing this class of applications. Besides programmability and ease of parallelization, fault tolerance is clearly important for data-intensive applications, because of their long running nature, and because of the potential for using a large number of nodes for processing massive amounts of data. Fault-tolerance has been an important attribute of map-reduce as well in its Hadoop implementation, where it is based on replication of data in the file system. Two important goals in supporting fault-tolerance are low overheads and efficient recovery. With these goals, this paper describes a different approach for enabling data-intensive computing with fault-tolerance. Our approach is based on an API for developing data-intensive computations that is a variation of map-reduce, and it involves an explicit programmer-declared reduction object. We show how more efficient fault-tolerance support can be developed using this API. Particularly, as the reduction object represents the state of the computation on a node, we can periodically cache the reduction object from every node at another location and use it to support failure-recovery. We have extensively evaluated our approach using two dataintensive applications. Our results show that the overheads of our scheme are extremely low, and our system outperforms Hadoop both in absence and presence of failures.
A compact nonlinear model for coplanar waveguides on silicon substrates

A wideband nonlinear equivalent circuit model for quasi-TEM coplanar waveguide (CPW) transmission lines fabricated on low-resistivity Si substrates is proposed and verified experimentally. The model includes nonlinear bias-dependent junction conductances and capacitances, which enable the model to scale with substrate doping concentration and transmission line geometry. Numerical calculation of the CPW capacitance, based on 2D solutions of Poisson's equation, as well as experimental investigations of the dependence of model parameters on substrate doping type (both n- and p-type) and doping concentration have been performed. Measurements of typical devices show excellent agreement between the model prediction and measured transmission line S-parameters from 100 MHz to 10 GHz. Analysis of the model indicates that a full back-to-back metal-semiconductor junction contact model is required for CPWs on n-type substrates, while the higher Schottky barrier height of typical metal contacts to p-type Si permits a simpler one-sided junction model for CPWs on p-type substrates.
Public record aggregation using semi-supervised entity resolution

This paper describes a highly scalable state of the art record aggregation system and the backbone infrastructure developed to support it. The system, called PeopleMap, allows legal professionals to effectively and efficiently explore a broad spectrum of public records databases by way of a single person-centric search. The backbone support system, called Concord, is a toolkit that allows developers to economically create record resolution solutions. The PeopleMap system is capable of linking billions of public records to a master data set consisting of hundreds of millions of person records. It was constructed using successive applications of Concord to link disparate public record data sets to a central person authority file. To our knowledge, the PeopleMap system is the largest of its kind. In contrast, the Concord support system is a novel record linkage tool that uses a new semi-supervised training technique called `surrogate learning' to enable the rapid development of record resolution solutions.
PC board design and fabrication using Schematics, PADS-PERFORM, and a laser printer

The software packages Schematics from MicroSim Corp. and PADS-PERFORM from PADS Software Inc. have been interfaced to give students an integrated environment where they can create schematics for documentation, simulate circuits, and design printed circuit boards. The software packages are available in evaluation versions. The circuits are limited to approximately 25 components but this is not a limitation for undergraduate projects. A package of parts has been developed at Northern Arizona University that contains part symbols and package outlines for parts in a "standard" lab kit. PADS-PERFORM can output artwork on the laser printer. A method for using the laser printer toner for resist when etching the boards is discussed.
Plasma ACTH and Cortisol Responses to TRF, Vasopressin or Hypoglycemia in Cushing's Disease and Nelson′s Syndrome

The response of plasma ACTH and/or cortisol concentrations to thyrotropin-releasing-factor (TRF), vasopressin, and insulin administration was determined in 5 patients with Nelson′s syndrome and 12 patients with untreated Cushing′s disease. TRF administration was associated with a mean increment of 267 pg/ml in plasma ACTH concentrations in patients with Nelson′s syndrome, and of 42 pg/ml in patients with Cushing′s disease. The increment in plasma cortisol concentrations in the latter group was 12 /Ltg%. No ACTH or cortisol response was observed in normal subjects. Patients with Cushing′s disease or Nelson′s syndrome exhibited significantly greater increments in plasma ACTH concentrations in response to vasopressin administration (P < .05, P< .02 respectively) than did normal subjects; the increment in cortisol concentration was also greater, (P < .05), in patients with Cushing′s disease than in normal subjects. No significant difference was present between patients with Cushing′s disease and Nelson′s synd...
Paranormal healing: what is the way forward?

In the August 2011 of Journal of Psychosomatic Research Easter and Watt report their findings from an elegant, albeit small study of paranormal healing on pain of arthritis patients [1]. Such studies may be relevant, not least because this population uses alternative treatments for symptom control more frequently than any other patient group [2]. Easter andWatt show that healing is ineffective, i.e., it is no better than no intervention in terms of improving general health or reducing pain. Belief in healing also did not affect the outcome. Yet a medium to large effect was noted for participants who were aware of receiving the verum treatment. This suggests that patients’ awareness of being treated maximises the placebo effect. Many different forms of paranormal healing exist and are popular in the United Kingdom, United States, and other countries. Some have religious connotations while others do not. All rely on some form of paranormal “energy” which allegedly enables the body to heal itself [3]. Numerous studies have tested whether healing is effective. Even though some have produced encouraging answers (and several investigations were suspected to be fraudulent and therefore falsepositive [4]), the overall picture is far from convincing. The most recent review of these data concluded that “the weight of the evidence [is] against the notion that distant healing is more than a placebo” [5]. As clinicians, should we or should we not use healing or encourage patients to use this approach? On the one hand, through a placebo response, it has the potential to ease the suffering of many patients, particularly, as Easter andWatt have shown [1], if they are aware that they receive this therapy. On the other hand, doing so might violate
Hypercholesterolemia suppresses Kir channels in porcine bone marrow progenitor cells in vivo.

Objective Inwardly-rectifying K+ (Kir) channels are responsible for maintaining membrane potentials in a variety of cell types including endothelial cells where they modulate endothelium-dependent vasorelaxation. The goal of this study is to determine the functional expression of Kir channels in porcine bone marrow-derived side population (BM-SP) cells that demonstrate phenotypes of endothelial progenitor cells (EPCs). We further asses the hypercholesterolemia sensitivity of Kir channels in BM-SP cells, which may play a key role in hypercholesterolemia-mediated regulation of EPCs.
A descriptive regional study of drug and alcohol use in pregnant women using results from urine drug testing by liquid chromatography-tandem mass spectrometry.

ABSTRACTBackground: Patterns of drug use during pregnancy may be changing. Identifying changes in pregnant women’s drug use may help to target prevention and treatment. Objective: To determine the regional prevalence of drug and alcohol use among pregnant women in Southern California. Methods: This was a prospective, descriptive study conducted at a university health system’s urban and suburban ambulatory obstetric offices. Included were pregnant women of all ages and trimesters. Excluded were non-pregnant women and women who had previously presented for an obstetric appointment during the data collection time period. Women provided a urine sample as part of routine care. Liquid chromatography-tandem mass spectrometry analysis of urine was performed for detection of a pre-selected sample of drugs and for alcohol. Descriptive statistics were performed. Results: A total of 295 urine samples were included. All trimesters were represented. A total of 14.2% of urine samples were positive for at least one of th...
The 1990 Valentine's Day Arctic Outbreak. Part I: Mesoscale and Microscale Structure and Evolution of a Colorado Front Range Shallow Upslope Cloud

Abstract The mesoscale and microscale structure and evolution of a shallow, upslope cloud is described using observations obtained during the Winter Icing and Storms Project (WISP) and model stimulations. The upslope cloud formed within a shallow arctic air mass that moved into the region east of the Rocky Mountains between 12 and 16 February and contained significant amounts of supercooled liquid water for nearly 30 h. Two distinct layers were evident in the cloud. The lower layer was near neutral stability (boundary layer air) and contained easterly upslope flow. The upper layer (frontal transition zone) was thermodynamically stable and contained southerly flow. Overlying the upslope cloud was a dry, southwesterly flow of 2025 m s −1, resulting in strong wind shear near cloud top. Within 10 km of the Rocky Mountain barrier, easterly low-level flow was lifted up and over the mountains. The above-described kinematic and thermodynamic structure produced three distinct mechanisms leading to the production ...
Professional Development Considerations for Makerspace Leaders, Part Two: Addressing “How?”

As makerspaces begin to move into school libraries and classrooms, there is a growing need for professional development to help K-12 educators answer common questions such as “what is a makerspace,” “why should I bother with a makerspace,” “how do I run a makerspace,” and “how do I teach from a makerspace?” In part one of this two-part series, content and professional development activities were recommended to help educators develop a basic understanding of what comprises a makerspace, what happens in a makerspace, and how the makerspace can benefit their curriculum. For educators interested in taking the next step, part two of this series includes recommended content and professional development activities to help them answer the “how” questions. This article summarizes related literature and best practices from maker leaders to ground recommended professional development activities that may be applied in workshops or in the authentic context of making.
Effect of iodine on absorption of cholesterol.

It is now an established and unequivocal fact that cholesterol is readily absorbed from the gastro-intestinal tract and that an increase may be demonstrated in the thoracic duct chyle after feeding. Relatively little is known, however, about the factors influencing this absorption. Thus, when a rise in the blood cholesterol of rabbits was prevented for several months by feeding potassium iodide with the cholesterol,1 it was considered possible that the iodide in some way prevented the absorption of the sterol, but no information bearing on this point was available.It seemed possible to approach the problem by feeding cholesterol to normal and iodized animals and determining the level of the cholesterol in the chyle. Unfortunately the small size of the thoracic duct in rabbits made it infeasible to use them for this purpose although it would have been desirable to carry out the work on the same species of animal used in the previous experiments. Dogs seemed to offer the least technical difficulty and accor...
Observations on the natural history and experiments on the reproductive strategy of hargeria rapax (Tanaidacea)

Information on the life cycle and seasonal ecology of Hargeria rapax, a tanaidacean common in coastal communities along the Atlantic shores of the southeastern United States and Gulf of Mexico, was obtained by systematically sampling the population in two tide pools located on Dauphin Island, Alabama, for 13 continuous months. Population size grew through spring, reached an abundance of > 10.0 individuals/cm2 by early summer and crashed by August. It remained below 1.0 individual/cm2 for the rest of the year. A migration to more optimal mesohaline conditions was proposed based on field and literature data to explain the rapid decrease and low numbers in population size. Females were present throughout the year, but numbers of gravid females peaked in June and January. Manca II stages were found only in the spring, suggesting that reproduction was successful only during this period. Males were few in number and occurred sporadically. Male to female ratios averaged 1:8. Laboratory cultures indicated that this tanaidacean has a protogynous reproductive strategy. The tubicolous paratanaidacean Hargeria (=Leptochelia) rapax (Harger) is a common meiofaunal component of protected intertidal estuarine communities of the northern Gulf of Mexico (Lang, 1973; Ogle, 1977; Subrahmanyan et al., 1976; Sikora and Sikora, 1982; and others), Chesapeake Bay (Boesch and Diaz, 1974), Duplin River, Georgia (Kneib, 1988), Indian River Lagoon, Florida (Stoner, 1983), and the mangrove communities of southwestern Florida (Odum and Heald, 1972). Heard (1979, 1981) collected this species in many softbottom shoreline habitats of the Mobile
Power for Detecting Treatment by Moderator Effects in Two- and Three-Level Cluster Randomized Trials:

Recently, there has been an increase in the number of cluster randomized trials (CRTs) to evaluate the impact of educational programs and interventions. These studies are often powered for the main...
Contingency Management to Promote Drug Abstinence

Abstract Contingency management (CM), in which positive consequences are delivered based on the evidence of drug abstinence, represents one of the most successful translations of behavior analytic principles and procedures to socially significant problem behavior. We discuss the history and contemporary applications of CM interventions to initiate and maintain abstinence across a range of drug classes. We also highlight innovations in CM that promise to increase access, sustainability, and cost effectiveness of this evidence-based behavioral intervention. We conclude with a brief discussion of considerations for implementation in clinical contexts and of methods to broaden the dissemination and implementation of CM.
Design and Static Magnetic Analysis of Magnetostrictive (Tb0.3Dy0.7Fe1.95) Fuel Injector with Flexible Piston Hydraulic Displacement Amplification

This paper presents the conceptual design of fuel injector based on giant magnetostrictive material, with displacement amplification mechanism. The permissible emission level EURO norms become stricter in case of fuel injection technology of modern combustion engine. The magnetic circuit of the magnetostrictive fuel injector is analyzed using finite element method. Based on the structure and working principle of our magnetostrictive fuel injector (MFI), the properties of driving magnetic field are researched.
Variability of FDG PET/CT signal and presentation of rare mucinous adenocarcinomas of the pancreas, appendix, ovary and rectum

1059 Learning Objectives To review variability of FDG PET/CT findings of rare mucinous adenocarcinomas (MA) with correlation to histopathological findings and other imaging modalities and to describe the pitfalls and limitations of FDG PET/CT and how to improve the confidence and accuracy in interpreting MA. Although PET/CT is useful for differentiating malignant from benign, some malignant pancreatic MA may present low FDG uptake while some benign MA may present high FDG uptake. A pictorial review of PET/CT findings are demonstrated of rare MA of the pancreas, appendix, ovary, rectum and colon with correlation to the histopathological findings and other imaging modalities. It is essential to understand the properties, pitfalls, and limitations of PET/CT in interpreting rare MA to improve accuracy. FDG uptake has been correlated with the number of viable tumor cells, the grade and the differentiation of tumors. Current PET/CT imaging technique has low sensitivity for MA. The pitfalls are mainly associated with the pathogenesis and histopathological features of MA. FDG uptake is positively correlated with cellularity in pancreatic MA, while FDG uptake is negatively correlated with the amount of mucin. Thus, PET/CT is limited particularly in hypocellular lesions of MA with abundant mucin. In addition, mucin production may be an indicator of the aggressiveness of the colorectum cancer but not an evidence of others. Recent studies showed that special types of mucin core proteins may play a role in assessing prognosis for some mucin-producing cancers; those mucin core proteins may provide potential imaging ability to evaluate malignant progression and prognosis. Tumor grade of MA was not predictive of tumor detectability using FDG PET. CT and MR are helpful for non-specific anatomic and histological images of MA, with no definite ability to differential malignant from benign and to make a prognosis of MA. Cases represented illustrate the use of PET/CT in the management of rare mucinous adenocarcinomas
Randomized Study of PMTO in Foster Care: Six-Month Parent Outcomes

Objective:This study examined the effects of Parent Management Training, Oregon (PMTO) model on parenting effectiveness and caregiver functioning.Method:Children in foster care with emotional and b...
On The Scientific and Humanistic Thinking of Erwin Schrödinger During His Last Years

In this day and age there is hardly any natural scientist who reflected on our existence from such a great variety of perspectives as Erwin Schrodinger did.
Aerosol detection using lidar-based atmospheric profiling

A compact light detection and ranging (LiDAR) is a system that provides aerosols profile measurements by identifying the aerosol scattering ratio as function of the altitude. The aerosol scattering ratios are used to obtain multiple aerosol intensive ratio parameters known as backscatter color ratio, depolarization ratio, and lidar ratio. The aerosol ratio parameters are known to vary with aerosol type, size, and shape. In this paper, we employed lidar measurements to detect the potential source of the aerosol in the neighborhood of the campus of Old Dominion University. The lidar is employed to collect measurements at several locations in the area of study. Then, the lidar ratio and the color ratio are retrieved from collected measurements. To find the source of aerosol in the measurements, a tracking algorithm is implemented and employed to track the concentration of that pollution in the data. The results show that the source of soot pollution in the area of study is Hampton Blvd, a major street, in the area of the campus where the diesel trucks travel between the ports in the city of Norfolk.
G69 Audit of CT head performed as part of‘skeletal survey’ among infants less than 1 year old, and its role in identifying ‘occult abusive head trauma’ when performed routinely

We present data that raises questions about the need for routine CT head in infants aged 0–12 months old with suspected physical abuse. We performed an audit of our compliance with the Joint RCPCH and RCR guidelines 2008, which recommend that infants under the age of 12 months with suspected physical abuse undergo a CT head as part of their skeletal survey to exclude occult injury. Methods We performed a retrospective analysis of infants aged 1 year or less who were investigated for suspected physical abuse with a skeletal survey. We reviewed whether CT head was performed in every case, and from case notes whether their presentation was symptomatic of Non-Accidental Head injury. The period of study was December 2011 – January 2015. Cases of sudden unexpected death in infancy were excluded, as were infants who had skeletal surveys for other clinical reasons. Results We reviewed 111 skeletal survey reports, which revealed 16 occult skeletal injuries (14.4%). 100/111 patients underwent a CT head, achieving 90.1% concordance with the national guideline. 58/100 CT scans were normal, all infants were asymptomatic and had routine CT scans. 42/100 were abnormal, 39/42 were symptomatic infants, scans undertaken urgently for presenting features of abusive head trauma (acute encephalopathy 23, significant impact trauma 14, suspected raised ICP 2). 3/42 infants had intracranial abnormalities of uncertain significance related to their underlying condition and not to abusive head trauma. CT Head did not reveal any occult non-accidental head injury in the asymptomatic cohort. Conclusion Only 3/100 CT showed occult abnormality which were not felt to be suggestive of abusive head trauma. Although the total number of infants is low, the yield for occult head trauma in this retrospective case series was negligible, less than that previously reported for infants without neurological concerns at presentation. We suggest that a larger, prospective study is needed to clearly establish the role of routine CT head in excluding occult injuries in the potentially abused infant. The yield from skeletal survey was 14.4% is in line with other published studies, suggesting that this investigation has a role in medical assessment of suspected physical abuse.
Effects of manipulating human tumor cell line expression of CYP1A1 on metabolic activation of and sensitivity to aminoflavone

4977 Aminoflavone (AF) is a potent anti-tumor agent with a unique activity profile in the NCI human tumor 60 cell line screen, consistant with a novel mechanism of action. We previously showed that AF induces expression of cytochromes P450 (CYP) 1A1/1A2 in MCF7 human breast cancer cells. In a panel of human tumor cell lines, we also demonstrated that AF was converted to reactive species that covalently bound to cellular macromolecules only in cell lines sensitive to AF (Kuffel, et al., Mol. Pharm. 62(1): 143-53, 2002). We now show that AF induced expression of CYP1A1/1A2 mRNA and protein only in AF-sensitive cell lines. Using a subset of two sensitive (MCF7 and T47D) and two negative (Hs578T and MDA-MB-435) tumor lines, we further show that induction of CYP1A1 is required for metabolic activation of AF, as measured by covalent binding. Using shRNA directed against CYP1A1, we observed reduced expression of CYP1A1 protein and a reduction in the metabolic activation of AF (covalent binding) in sensitive cells. Conversely, AF-resistant cells transfected with CYP1A1 exhibited an increase in metabolic activation. This research was supported in part by a Mary Kay Ash Charitable Foundation Research Grant (MMA).
Using a theoretical model of communal coping to understand changes in language brokers’ coping patterns: Implications for Latina/o early adolescents’ brokering stress and efficacy

ABSTRACTLanguage brokering occurs when immigrant youth linguistically and culturally mediate for family and members of U.S. mainstream culture. Under some circumstances, brokering can be stressful. Based on a theoretical model of communal coping, this study utilized two waves of survey data from 342 Latina/o sixth- to eighth-grade students to identify different types of copers: (a) communal copers, (b) tentative copers, and (c) declined-ownership copers. Communal copers reported greater brokering stress than tentative brokers in the middle of the year, but not by the end of the year. Communal copers reported greater brokering efficacy than tentative copers in the middle and end of the year. Declined-ownership copers consistently had the lowest brokering stress and moderate brokering efficacy.
Discharge to inpatient facilities after lumbar fusion surgery is associated with increased postoperative venous thromboembolism and readmissions.

Abstract BACKGROUND CONTEXT Postdischarge care is a significant source of cost variability after posterior lumbar fusion surgery. However, there remains limited evidence associating postdischarge inpatient services and improved postoperative outcomes, despite the high cost of these services. PURPOSE To determine the association between posthospital discharge to inpatient care facilities and postoperative complications. STUDY DESIGN A retrospective review of all 1- to 3-level primary posterior lumbar fusion cases in the 2010-2014 National Surgical Quality Improvement Program registry was conducted. Propensity scores for discharge destination were determined based on observable baseline patient characteristics. Multivariable propensity-adjusted logistic regressions were performed to determine associations between discharge destination and postdischarge complications, with adjusted odds ratios (OR) and 95% confidence intervals (CI). RESULTS A total of 18,652 posterior lumbar fusion cases were identified, 15,234 (82%) were discharged home, and 3,418 (18%) were discharged to continued inpatient care. Multivariable propensity-adjusted analysis demonstrated that being discharged to inpatient facilities was independently associated with higher risk of thromboembolic complications (OR [95% CI]: 1.79 [1.13–2.85]), urinary complications, (1.79 [1.27–2.51]), and unplanned readmissions (1.43 [1.22–1.68]). CONCLUSIONS Discharge to continued inpatient care versus home after primary posterior lumbar fusion is independently associated with higher odds of certain major complications. To optimize clinical outcomes as well as cost savings in an era of value-based reimbursements, clinicians and hospitals should consider further investigation into carefully investigating which patients might be better served by home discharge after surgery.
Lung Isolation Techniques in Patients With Early-Stage or Long-Term Tracheostomy: A Case Series Report of 70 Cases and Recommendations

Objectives Lung isolation techniques are designed to facilitate surgical exposure in thoracic surgical patients and provide one-lung ventilation (OLV). Some patients have a tracheostomy in situ, which makes the management of the airway and OLV difficult. The objective of this retrospective study was to review cases that had a tracheostomy prior to thoracic surgery and evaluate the clinical use and efficiency with the airway management and lung isolation devices. Design This was a retrospective data analysis. Setting Tertiary care university hospital. Interventions After institutional review board approval, the authors reviewed 3,225 charts of patients who had thoracic surgery involving OLV. Seventy patients were identified who had tracheostomy in situ. Each case was reviewed regarding airway management and lung isolation technique. Measurements and Main Results The authors identified 70 patients who had a tracheostomy in situ. The cases were divided into 2 groups: a fresh tracheostomy stoma 7 days (n = 64). The authors collected information regarding the devices used to manage the airway and lung isolation techniques. The devices used to manage the airway include the Shiley cuffed low pressure tracheostomy tube, single-lumen endotracheal tube (SLT), or double-lumen endotracheal tube (DLT). Devices used to manage OLV included SLTs, with or without bronchial blockers, or DLTs. Flexible fiberoptic bronchoscopy was used to assess the airway and confirm the position of the lung isolation device. Six cases had an early-stage fresh tracheostomy stoma where the Shiley tracheostomy tube was used for ventilation followed by the use of a bronchial blocker. In contrast, for the patients who had a long-term stoma, the following devices were used: (1) a SLT plus a bronchial blocker in 38 cases, a Shiley tracheostomy tube plus bronchial blocker in 15 cases, use of a SLT guided into a selective bronchus in 7 cases, and use of a DLT in 4 cases. In all cases, flexible fiberoptic bronchoscopy was used and no complications occurred secondary to airway management or OLV. Conclusion In patients undergoing thoracic surgery and OLV, and with a fresh tracheostomy stoma in situ, the authors recommend the use of the Shiley tracheostomy tube plus a bronchial blocker. In patients with a long-term tracheostomy stoma, a SLT can be used selectively to intubate 1 bronchus. In addition, an SLT or a Shiley tube can be used in conjunction with an independent bronchial blocker, such as the Arndt wire-guided bronchial blocker, Cohen tip-deflecting blocker, Fuji Uniblocker, or EZ-Blocker. DLTs are the least frequently used device for OLV in tracheostomized patients.
A System Supporting Flexible Distributed Real-Time Music Processing

Local-area networks offer a means to interconnect personal computers to achieve more processing, input, and output for music and multimedia performances. The distributed, realtime object system, Aura, offers a carefully designed architecture for distributed real-time processing. In contrast to streaming audio or MIDI-over-LAN systems, Aura offers a general real-time message system capable of transporting audio, MIDI, or any other data between objects, regardless of whether objects are located in the same process or on different machines. Measurements of audio synthesis and transmission to another computer demonstrate about 20ms of latency. Practical experience with protocols, system timing, scheduling, and synchronization are discussed.
Response of starter pigs to supplementation of corn-soybean meal diets with organic acids.

Four growth experiments were conducted to assess the effects of organic acid supplementation on performance of starter and finisher pigs. Three 4-wk starter experiments utilized 392 pigs fed simple corn-soybean meal diets. A fourth experiment employed 135 finisher pigs in a 6-wk study. Each of the starter experiments was initiated immediately after weaning; piglets were 30 +/- 3 d of age. In Exp. 1, weanling pigs fed a 19% crude protein, simple corn-soybean meal diet were compared with pigs fed similar diets supplemented with 2% propionic, fumaric, or citric acid. Addition of each acid improved (P less than .07) efficiency of gain, while propionate depressed (P less than .05) feed intake. Additions of 1, 2, 3 or 4% fumarate were made in Exp. 2, resulting in linear daily gain and feed efficiency improvements (P less than .05). In Exp. 3, a possible protein-sparing effect of fumaric acid was investigated. Increasing protein levels from 16 to 20% improved daily gain (P less than .01) and feed efficiency (P less than .0001); fumarate supplementation (2%) increased (P less than .01) gain:feed. However, there was no protein X fumaric acid interaction. In Exp. 4, no treatment effects were noted with performance of finisher pigs fed a 14% crude protein, corn-soybean meal diet was compared with that of pigs fed similar diets supplemented with 1.5 or 3% fumaric acid.
Complex Anomaly-Free Representations for Grand Unification

Complete list of the complex representations of Lie groups that satisfy the anomaly freedom and asymptotic freedom has recently been given by E. Eichten, I.-G. Koh and myself.1) We first give a brief summary of the results of Ref. 1 and then discuss the application of such representations to the composite models based on another recent work by I.-G. Koh, A. N. Schellekens and myself.2) The role of Fermi-statistics and the method of decompositions of tensor products with definite permutation property are explained in two examples.
The Utility of Endoscopic Ultrasound-Guided Brachytherapy in Liver Metastasis: A Case Report and Review of the Literature.

Endoscopic ultrasound guided brachytherapy (EGBT) has been reported to be useful in certain malignancies including esophageal and pancreatic cancers. Percutaneous or surgical placement of radioactive seeds into the liver secondaries (brachytherapy) has been done successfully, however, the utility of EGBT in liver metastasis remains largely unclear. In this case report, we demonstrate the safety, efficacy and feasibility of EUS guided brachytherapy (EGBT) in liver metastasis secondary to leiomyosarcoma.