cssi/SciSciGPT-SciSciNet huggingface dataset:
W04-02 Psychodynamically oriented crisis hospitalisation and ambulatory combination treatement for borderline patients: an introduction

The following educational topics will be carefully addressed: a. to establish a coherent model of the borderline syndrome as a complex, heterogeneous reaction resulting from the interaction of psychobiological vulnerabilities, psychosocial stressors and abnormal mental processes; b. to teach how new data from recent investigations of the clinical course of the borderline crisis are changing our view of both the scopes and the limitations of mental health policies for borderline patients; c. to review the several issues associated with adequate acute service provision for borderline patients in order to define a set of well structured recommendations for good quality, comprehensive emergency services organisation and acute treatment delivery; d. to teach a well structured, simple, cost-effective, easy to implement psychodynamic crisis intervention program with specific accent on: case management, risk management, facilitating an alliance, inactivating pathological personality traits triggered from acute traumatic experiences, empathic exploration of distressing feelings, conveying insight on repetitive patterns of ego syntonic masochistic behaviour, active support for problem solving; e. to teach the main aspects of an innovative brief psychodynamic psychotherapy program (mourning focused psychodynamic psychotherapy) model and its relevance to increased cost-effectiveness of psychiatric treatment among acute patients with borderline emotional crisis triggered from traumatic abandonment and other stressful life events. The course is intended for people with an experience in the field of personality disorders and an interest in combining psychobiological science and psychotherapeutic wisdom to improve acute treatment and psychiatric services.
Observation of discrete electronic states in a zero-dimensional semiconductor nanostructure.

Electronic transport through a three-dimensionally confined semiconductor quantum well (``quantum dot'') has been investigated. Fine structure observed in resonant tunneling through the quantum dot corresponds to the discrete density of states of a zero-dimensional system.
Common Genitourinary Infections

Vulvovaginal pain, itching, and burning are a triad of symptoms for which women frequently seek health care. Often accompanied by vaginal discharge and dysuria, these symptoms account for as many as 5 million office visits a year. Proper assessment and management of these symptoms by nurses, nurse practitioners, and nurse midwives can help to substantially improve a woman's quality of life and help prevent long‐term problems. Several differing syndromes or infections can be the cause of these symptoms. The most common causes are discussed, and a plan for management and prevention is presented.
High-resolution two-photon spectroscopy of the NO23pσ 2Σu+ Rydberg state

Abstract The high-resolution two-photon absorption spectrum of the X 2 A 1 (000)→3pσ 2 Σ u + (000) system in NO 2 shows rotational fine structure characteristic of a bent-to-linear transition. This structure is well fit by a simple Hamiltonian incorporating an upper state rotational constant B XXX = 0.419 ± 0.001 cm −1 and a spin-rotation coupling constant ψ = 0.150 ± 0.005 cm −1 . These parameters evidence a somewhat contracted Rydberg core NO bond length of 1.126 ± 0.002 A with moderate Rydberg electron-core interaction.
On testing Hamiltonicity of graphs

Abstract Let us fix a function f ( n ) = o ( n ln n ) and real numbers 0 ≤ α β ≤ 1 . We present a polynomial time algorithm which, given a directed graph G with n vertices, decides either that one can add at most β n new edges to G so that G acquires a Hamiltonian circuit or that one cannot add α n or fewer new edges to G so that G acquires at least e − f ( n ) n ! Hamiltonian circuits, or both.
Computer algebra and interpolation: a lesson plan

Abstract Polynomial interpolation and related numerical analysis questions are used to take users of computer algebra systems from issuing one-liners to writing more complex programs. An alternate use of the outlined lessons is to introduce students to interpolation and acquaint them with splines and numerical differentiation. Constructive symbolic derivations of formulae for polynomial interpolants are presented. Numerical differentiation formulae are derived using them. Necessary background material is introduced. The examples and assignments can be done using any general purpose symbolic manipulator; complete codes using the computer algebra system AXIOM are given.
Preoperative evaluation of the lung resection candidate

Lung resection provides the greatest likelihood of cure for patients with localized lung cancer, but is associated with a risk of mortality, decreased postoperative lung function, and other complications. Lung function testing using spirometry, diffusing capacity of the lung for carbon monoxide, and peak oxygen consumption helps predict the risk of postoperative complications including mortality. Predicting postoperative lung function using the proportion of lung segments to be resected, radionuclide scanning, or other methods is important for assessing surgical risk. The American College of Chest Physicians, the European Respiratory Society/European Society of Thoracic Surgeons and the British Thoracic Society guidelines provide detailed algorithms for preoperative risk assessment, but their recommended approaches differ somewhat. Smoking cessation and pulmonary rehabilitation are perioperative measures that can improve patients' the short- and long-term outcomes.
Modeling the electrostatic self-assembly (ESA) fabrication process using cellular automata

The electro-static self-assembly process, or ESA, has proved to be extremely successful in creating multi-layer coatings with properties that can be optimized for particular applications. In this process, almost any surface with charged functional groups can be used as a substrate. Sequential dipping in solutions having ions of opposite charge builds up the layers through ionic bonding. Multi- functional bio-compatible coatings on MEMS deices intended for use in-vivo could be formed using ESA. In this paper, we describe two different models of the process based on adaptive computational techniques using cellular automata. The output of the models consists of three parameters as a function of layer: layer coverage, total average coating height and layer roughness. The result of the models are compared to experimental data to determine which of them more accurately mirrors the ESA process.© (2001) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Confidence Intervals for Ground-Water Models Using Linearization, Likelihood, and Bootstrap Methods

Four methods were applied to obtain confidence intervals for selected dependent variables from a nonlinear regression formulation of a ground-water flow model. The methods examined are (1) the linearization method, (2) the likelihood method, (3) a simple, percentile bootstrap method, and (4) a regression-based percentile bootstrap method that is a generalization of the first one. The methods were applied to a highly nonlinear regression model of a hypothetical ground-water system involving an infiltrating stream crossing a heterogeneous aquifer. Confidence intervals were computed for a hydraulic head and a parameter that is proportional to the streamflow infiltration rate. All confidence intervals computed by the likelihood method are virtually exact. Confidence intervals for hydraulic head by the linearization, likelihood, and the second bootstrap methods are similar, but confidence intervals by the first bootstrap method are very different and highly inaccurate. Confidence intervals for the streamflow infiltration parameter by the linearization and first bootstrap methods are identical and inaccurate; confidence intervals by the second bootstrap method lie between those by the likelihood and the other two methods. These characteristics of the confidence intervals result because (1) the regression model is highly nonlinear, and (2) much of the nonlinearity can be removed by some transformation of model parameters.
Do Collective Atomic Fluctuations Account for Cooperative Effects? Molecular Dynamics Studies of the U1A−RNA Complex

A complete understanding of gene expression relies on a comprehensive understanding of the protein−RNA recognition process. However, the study of protein−RNA recognition is complicated by many factors that contribute to both binding affinity and specificity, including structure, energetics, dynamical motions, and cooperative interactions. Several recent studies have suggested that energetic coupling between residues contributes to formation of the complex between the U1A protein and stem loop 2 of U1 snRNA as a consequence of a cooperative network of interactions. We have performed molecular dynamics simulations on the U1A−RNA complex, including explicit water and counterions, and analyzed the results based on the calculated positional cross-correlations of atomic fluctuations. The results indicate that cross-correlations calculated on a per residue basis agree well with the observed inter-residue cooperativity and predict that the networks identified to date may also be coupled into an extensive hyper-ne...
ADP-ribosylation Factor 1-independent Protein Sorting and Export from the trans-Golgi Network

Polarized epithelial cells efficiently sort newly synthesized apical and basolateral proteins into distinct transport carriers that emerge from the trans-Golgi network (TGN), and this sorting is recapitulated in nonpolarized cells. While the targeting signals of basolaterally destined proteins are generally cytoplasmically disposed, apical sorting signals are not typically accessible to the cytosol, and the transport machinery required for segregation and export of apical cargo remains largely unknown. Here we investigated the molecular requirements for TGN export of the apical marker influenza hemagglutinin (HA) in HeLa cells using an in vitro reconstitution assay. HA was released from the TGN in intact membrane-bound compartments, and export was dependent on addition of an ATP-regenerating system and exogenous cytosol. HA release was inhibited by guanosine 5'-O-(3-thiotriphosphate) (GTPgammaS) as well as under conditions known to negatively regulate apical transport in vivo, including expression of the acid-activated proton channel influenza M2. Interestingly, release of HA was unaffected by depletion of ADP-ribosylation factor 1, a small GTPase that has been implicated in the recruitment of all known adaptors and coat proteins to the Golgi complex. Furthermore, regulation of HA release by GTPgammaS or M2 expression was unaffected by cytosolic depletion of ADP-ribosylation factor 1, suggesting that HA sorting remains functionally intact in the absence of the small GTPase. These data suggest that TGN sorting and export of influenza HA does not require classical adaptors involved in the formation of other classes of exocytic carriers and thus appears to proceed via a novel mechanism.
An empirical study of the impact of team size on software development effort

In this paper, we investigate the impact of team size on the software development effort. Using field data of over 200 software projects from various industries, we empirically test the impact of team size and other variables--such as software size in function points, ICASE tool and programming language type--on software development effort. Our results indicate that software size in function points significantly impacts the software development effort. The two-way interactions between function points and use of ICASE tool, and function points and language type are significant as well. Additionally, the interactions between team size and programming language type, and team size and use of ICASE tool were all significant.
CNS neuroplasticity and salt-sensitive hypertension induced by prior treatment with subpressor doses of ANG II or aldosterone

Although sensitivity to high dietary NaCl is regarded to be a risk factor for cardiovascular disease, the causes of salt-sensitive hypertension remain elusive. Previously, we have shown that rats p...
Priming Aphytis: behavioral modification of host selection by exposure to a synthetic contact kairomone

The introduced parasitoid, Aphytis melinus DeBach (Hymenoptera : Aphelinidae), utilizes a kairomone, O-caffeoyltyrosine, to recognize California red scale, Aonidiella aurantii (Maskell) (Homoptera : Diaspididae). Wasps used in augmentative release programs for California red scale on California citrus are reared on oleander scale, Aspidiotus nerii Bouche (Homoptera : Diaspididae), themselves reared on squash. The goals of this study were : 1) to determine if long-term rearing on oleander scale had caused A. melinus to develop a preference for oleander scale, and 2) to determine if the preference of oleander-reared A. melinus for California red scale might be enhanced by exposing them to synthetic O-caffeoyltyrosine prior to release. Wasps that were removed from their hosts as pupae and allowed to emerge as adults isolated from their hosts retained a strong preference for California red scale regardless of rearing host. This preference was reduced if wasps were allowed to emerge from oleander scale, thus acquiring early adult experience with oleander scale. The preference for California red scale was restored, however, by exposing wasps reared on oleander scale to synthetic O-caffeoyltyrosine prior to bioassay. Exposure of A. melinus reared in commercial insectaries to O-caffeoyltyrosine prior to release may be a means to improve the effectiveness of such wasps in augmentative release programs to control California red scale.
The transition from TEM-like mode to plasmonic mode in finite-width THz parallel-plate waveguide

We report the near-field measurement of the electric field distribution inside the metal PPWG. We observe the transition from TEM-like mode to plasmonic mode. This mode transition depends on the geometry of the waveguide.
Optical parametric oscillators pumped by population-trapped atoms.

We describe an optical parametric oscillator that is pumped by population-trapped atoms that are prepared with maximum coherence. The oscillator is based on the use of an effective nonlinear susceptibility that is of the same order as the linear susceptibility. Because the parametric gain is obtained in a single coherence length, the gain bandwidth can exceed the degenerate frequency. In Pb vapor the calculated gain is maximized at 1.88 µm and has a bandwidth of ∼7500 cm-1.
Effects of Background on Gamma-Ray Detection for Mobile Spectroscopy and Imaging Systems

The presence of gamma-ray background significantly reduces detection sensitivity when searching for radioactive sources in the field, particularly in mobile systems which must contend with a variable background that is not known a priori . An extensive survey of the background was performed in the San Francisco Bay Area using both sodium iodide and high-purity germanium detectors, covering a wide variety of environments that might be encountered in an operational scenario. This data was used as a basis for source injection in a moving detector scenario in order to assess the effects of the background on different detection approaches. Both imaging and spectroscopic algorithms were implemented for the sodium iodide array, and their performances are compared for a variety of source energies and stand-off distances in the presence of the measured background.
A tool for empirical forecasting of major flares, coronal mass ejections, and solar particle events from a proxy of active-region free magnetic energy

Space Radiation Analysis Group (SRAG) at Johnson Space Center, which is responsible for the monitoring and forecasting of radiation exposure levels of astronauts. The new software tool is designed for the empirical forecasting of M‐ and X‐class flares, coronal mass ejections, and solar energetic particle events. For each type of event, the algorithm is based on the empirical relationship between the event rate and a proxy of the active region’s free magnetic energy. Each empirical relationship is determined from a data set of ∼40,000 active‐region magnetograms from ∼1300 active regions observed by SOHO/Michelson Doppler Imager (MDI) that have known histories of flare, coronal mass ejection, and solar energetic particle event production. The new tool automatically extracts each strong‐field magnetic area from an MDI full‐disk magnetogram, identifies each as a NOAA active region, and measures the proxy of the active region’s free magnetic energy from the extracted magnetogram. For each active region, the empirical relationship is then used to convert the free‐magnetic‐energy proxy into an expected event rate. The expected event rate in turn can be readily converted into the probability that the active region will produce such an event in a given forward time window. Descriptions of the data sets, algorithm, and software in addition to sample applications and a validation test are presented. Further development and transition of the new tool in anticipation of SDO/HMI are briefly discussed.
Herringbone and triangular patterns of dislocations in Ag, Au, and AgAu alloy films on Ru(0 0 0 1)

Abstract We have studied the dislocation structures that occur in films of Ag, Au, and Ag0.5Au0.5 alloy on a Ru(0 0 0 1) substrate. Monolayer (ML) films form herringbone phases while films two or more layers thick contain triangular patterns of dislocations. We use scanning tunneling microscopy (STM) and low-energy electron diffraction (LEED) to determine how the film composition affects the structure and periodicity of these ordered structures. One layer of Ag forms two different herringbone phases depending on the exact Ag coverage and temperature. Low-energy electron microscopy (LEEM) establishes that a reversible, first-order phase transition occurs between these two phases at a certain temperature. We critically compare our 1 ML Ag structures to conflicting results from an X-ray scattering study [H. Zajonz et al., Phys. Rev. B 67 (2003) 155417]. Unlike Ag, the herringbone phases of Au and AgAu alloy are independent of the exact film coverage. For two layer films in all three systems, none of the dislocations in the triangular networks thread into the second film layer. In all three systems, the in-plane atomic spacing of the second film layer is nearly the same as in the bulk. Film composition does, however, affect the details of the two layer structures. Ag and Au films form interconnected networks of dislocations, which we refer to as “trigons.” In 2 ML AgAu alloy, the dislocations form a different triangular network that shares features of both trigon and moire structures. Yet another well-ordered structure, with square symmetry, forms at the boundaries of translational trigon domains in 2 ML Ag films but not in Au films.
Economic analysis of the Mediterranean Lifestyle Program for postmenopausal women with diabetes.

PURPOSE The purpose of this study was to evaluate costs associated with the primary intervention of the Mediterranean Lifestyle Program (MLP), which targeted postmenopausal women with type 2 diabetes at risk for coronary heart disease. METHODS Using retrospective data collected during MLP development and implementation, the authors estimated costs for the first 6 months relative to the usual care condition and incremental costs per behavioral, biologic, and quality-of-life change. Sensitivity analyses were conducted using variations in inflation rates, implementation settings, labor and nonlabor inputs, and market wage rates. RESULTS Of the sample of 279 study participants, 163 were randomized into the MLP condition. Total intervention costs were estimated at $211 061 ($148 022 direct costs) or $1295 per MLP participant relative to usual care ($908 direct costs). This translates to $3808 per average change in coronary heart disease risk as measured by an average 1-point reduction in hemoglobin A1C. Relative to other measured improvements, this corresponds to $2345 per unit reduction in body mass index and $644 per unit improvement in Problem Areas in Diabetes Quality-of-Life Self-care Summary score, and a $196 per-gram reduction in intake of saturated fatty acids as noted by the Food Frequency Questionnaire. A significant portion of the direct costs were related to the resources used during the recruitment phase. CONCLUSIONS Providing a relatively intensive lifestyle self-management program for this high-risk group is associated with modest incremental costs compared with usual care, making the program potentially appealing to policy makers.
Identification in Organizations: An Examination of Four Fundamental Questions

>> The literature on identification in organizations is surprisingly diverse and large. This article reviews the literature in terms of four fundamental questions. First, under “What is identification?,” it outlines a continuum from narrow to broad formulations and differentiates situated identification from deep identification and organizational identification from organizational commitment. Second, in answer to “Why does identification matter?,” it discusses individual and organizational outcomes as well as several links to mainstream organizational behavior topics. Third, regarding “How does identification occur?,” it describes a process model that involves cycles of sensebreaking and sensegiving, enacting identity and sensemaking, and constructing identity narratives. Finally, under “One or many?,” it discusses team, workgroup, and subunit; relational; occupational and career identifications; and how multiple identifications may conflict, converge, and combine.
Validation of an automated latex particle–enhanced immunoturbidimetric von Willebrand factor activity assay

Background Laboratory diagnosis of von Willebrand disease (VWD) requires accurate measurement of plasma von Willebrand factor (VWF) activity. Objectives To evaluate laboratory characteristics, diagnostic accuracy and testing utilities of an automated latex particle-enhanced immunoturbidimetric VWF assay (VWF:Lx) based on a monoclonal antibody recognizing the VWF-platelet glycoprotein (GP) Ib binding domain. Methods Laboratory characteristics including lower detection limit, linearity, precision, sample stability, and method comparison between VWF:Lx and VWF ristocetin cofactor activity by platelet aggregometry (VWF:RCo) were examined. To assess VWF:Lx diagnostic accuracy, 492 patient plasma samples, including 40 previously characterized VWD patient samples, were tested for VWF antigen (VWF:Ag) and VWF:RCo by either aggregometry or flow cytometry, and VWF:Lx with supplemental VWF multimer analysis when indicated. Based on results of VWF:Ag, VWF:RCo and VWF multimer analysis, and available clinical information, samples were categorized as: normal; VWD types 1, 2A/B, 2M, or severe 1 vs. 2M; or acquired VWF abnormalities (AVWA) due to subtle loss of highest molecular weight multimers. Results VWF:Lx had excellent laboratory characteristics and linear correlation with VWF:RCo (R(2) = 0.93). VWF:Lx accurately classified virtually all normal and VWD patient samples. Compared with VWF:RCo, VWF:Lx had superior sensitivity and specificity for distinguishing severe type 1 vs. 2M VWD and identifying AVWA. A proposed screening panel comprising VWF:Ag and VWF:Lx had 100% and 83% sensitivity for detecting VWD and AVWA, respectively. Conclusions VWF:Lx has excellent laboratory characteristics and diagnostic accuracy compared with VWF:RCo, and can be used as part of an initial VWD screening panel and as a supplementary test.
Large Hexagonal Bi‐ and Trilayer Graphene Single Crystals with Varied Interlayer Rotations

Bi- and trilayer graphene have attracted intensive interest due to their rich electronic and optical properties, which are dependent on interlayer rotations. However, the synthesis of high-quality large-size bi- and trilayer graphene single crystals still remains a challenge. Here, the synthesis of 100 μm pyramid-like hexagonal bi- and trilayer graphene single-crystal domains on Cu foils using chemical vapor deposition is reported. The as-produced graphene domains show almost exclusively either 0° or 30° interlayer rotations. Raman spectroscopy, transmission electron microscopy, and Fourier-transformed infrared spectroscopy were used to demonstrate that bilayer graphene domains with 0° interlayer stacking angles were Bernal stacked. Based on first-principle calculations, it is proposed that rotations originate from the graphene nucleation at the Cu step, which explains the origin of the interlayer rotations and agrees well with the experimental observations.
Identification of a high affinity nucleocapsid protein binding element from the bovine leukemia virus genome.

Abstract Retroviral genome recognition is mediated by interactions between the nucleocapsid (NC) domain of the virally encoded Gag polyprotein and cognate RNA packaging elements that, for most retroviruses, appear to reside primarily within the 5′-untranslated region (5′-UTR) of the genome. Recent studies suggest that a major packaging determinant of bovine leukemia virus (BLV), a member of the human T-cell leukemia virus (HTLV)/BLV family and a non-primate animal model for HTLV-induced leukemogenesis, resides within the gag open reading frame. We have prepared and purified the recombinant BLV NC protein and conducted electrophoretic mobility shift and isothermal titration calorimetry studies with RNA fragments corresponding to these proposed packaging elements. The gag -derived RNAs did not exhibit significant affinity for NC, suggesting an alternate role in packaging. However, an 83-nucleotide fragment of the 5′-UTR that resides just upstream of the gag start codon binds NC stoichiometrically and with high affinity ( K d = 136 ± 21 nM). These nucleotides were predicted to form tandem hairpin structures, and studies with smaller fragments indicate that the NC binding site resides exclusively within the distal hairpin (residues G369–U399, K d = 67 ± 8 nM at physiological ionic strength). Unlike all other structurally characterized retroviral NC binding RNAs, this fragment is not expected to contain exposed guanosines, suggesting that RNA binding may be mediated by a previously uncharacterized mechanism.
The sensory systems and feeding behavior of leafhoppers. II. A comparison of the sensillar morphologies of several species (Homoptera: Cicadellidae).

The ultrastructure of the sensilla, and other structures, within the precibaria of eight species from three subfamilies of leafhoppers (Homoptera: Cicadellidae) were examined with scanning electron microscopy. The types and grouping of the 20 precibarial sensilla in seven of these species were similar to those observed previously in Macrosteles fascifrons Stal. Oncometopia nigricans (Walker) also displayed similar sensilla groups; however, it had 30 sensilla. The species examined differed chiefly in the exact location and arrangement of the sensilla. The possible significance of the differences relative to leafhopper feeding is discussed. The precibarial chemosensilla may provide chemosensory evaluation of fluid in the food canal and precibarium prior to ingestion or egestion.
Di-n-Butyl Phthalate Disrupts the Expression of Genes Involved in Cell Cycle and Apoptotic Pathways in Mouse Ovarian Antral Follicles

Di-n-butyl phthalate (DBP) is present in many consumer products, such as infant, beauty, and medical products. Several studies have shown that DBP causes reproductive toxicity in rodents, but no studies have evaluated its effects on ovarian follicles. Therefore, we used a follicle culture system to evaluate the effects of DBP on antral follicle growth, cell cycle and apoptosis gene expression, cell cycle staging, atresia, and 17bestradiol (E 2 ) production. Antral follicles were isolated from adult CD-1 mice and exposed to DBP at 1, 10, 100, and 1000 lg/ ml for 24 or 168 h. Follicles treated with vehicle or DBP at 1– 100 lg/ml grew over time, but DBP at 1000 lg/ml significantly suppressed follicle growth. Regardless of effect on follicle growth, DBP-treated follicles had decreased mRNA for cyclins D2, E1, A2, and B1 and increased p21. Levels of the proapoptotic genes Bax, Bad, and Bok were not altered by DBP treatment, but DBP 1000 lg/ml increased levels of Bid and decreased levels of the antiapoptotic gene Bcl2. DBP-treated follicles contained significantly more cells in G 1 phase, significantly less cells in S, and exhibited a trend for fewer cells in G 2 . Although DBP did not affect E 2 production and atresia at 24 h, follicles treated with DBP had reduced levels of E 2 at 96 h and underwent atresia at 168 h. These data suggest that DBP targets antral follicles and alters the expression of cell cycle and apoptosis factors, causes cell cycle arrest, decreases E 2 , and triggers atresia, depending on dose. 17b-estradiol, antral follicle, apoptosis, atresia, cell cycle, ovary, phthalate, toxicology
Message Framing Strategies to Increase Influenza Immunization Uptake Among Pregnant African American Women

We explored the attitudes, opinions, and concerns of African American women regarding influenza vaccination during pregnancy. As influenza immunization coverage rates remain suboptimal in the United States among this population, we elicited message framing strategies for multicomponent interventions aimed at decreasing future incident cases of maternal and neonatal influenza. Semi-structured in-depth interviews (N = 21) were conducted with pregnant African American women at urban OB/GYN clinics who had not received an influenza vaccine. Interviews were transcribed, subjected to intercoder reliability assessment, and content analyzed to identify common thematic factors related to acceptance of the influenza vaccine and health communication message preferences. Four major themes were identified. These were communication approaches, normal vaccine behavior, pregnancy vaccination, and positive versus negative framing. Two strong themes emerged: positively-framed messages were preferred over negatively-framed messages and those emphasizing the health of the infant. Additionally, previous immunization, message source, and vaccine misperceptions also played important roles in decision-making. The majority of women indicated that positively framed messages focusing on the infant’s health would encourage them to receive an influenza vaccine. Messages emphasizing immunization benefits such as protection against preterm birth and low birth weight outcomes have potential to overcome widespread negative community perceptions and cultural beliefs. Additionally, messages transmitted via interpersonal networks and social media strongly influence motivation to obtain vaccination during pregnancy. The findings of this study will assist in developing tailored messages that change pregnant African American women’s influenza vaccination decision-making to achieve improved coverage.
Learning elsewhere: tales from an extracurricular game development competition

In response to students' overwhelming interest in game development and a cumbersome curriculum change process, we hosted at our large university a year-long extracurricular competition in which students designed and implemented video games. Monetary prizes were made possible by a private grant. Our goals were to give students a chance to learn outside of the classroom and to break down institutional barriers that pigeonhole students into compartmentalized skill sets. We believe the competition is worth repeating at our university and elsewhere, but several issues should be addressed first. In this experience report, we share our model for the competition and critique it based on student feedback.
An improved time integrator for finite element analysis

Several modifications to the widely used time integration scheme of Gresho et al.1 are suggested. The advantages of the modified time integrator are demonstrated by means of several simple example problems.
ROBUST INFERENCE FOR THE MEAN IN THE PRESENCE OF SERIAL CORRELATION AND HEAVY-TAILED DISTRIBUTIONS

The problem of statistical inference for the mean of a time series with possibly heavy tails is considered. We first show that the self-normalized sample mean has a well-defined asymptotic distribution. Subsampling theory is then used to develop asymptotically correct confidence intervals for the mean without knowledge (or explicit estimation) either of the dependence characteristics, or of the tail index. Using a symmetrization technique, we also construct a distribution estimator that combines robustness and accuracy: it is higher-order accurate in the regular case, while remaining consistent in the heavy tailed case. Some finitesample simulations confirm the practicality of the proposed methods.
Future directions and research needs.

In this paper, three perspectives for indoor air issues are considered: a) air inside of our homes and offices is a major component of our overall living environment and has potentially great impac...
Performance capabilities of the ring network circulator for integrated circuits

The theoretical model of a ring network junction circulator introduced in 1965 is re-examined and further elaborated, in view of its prospects for compatibility with accomplished and anticipated advances in microcircuit technology. Following a brief review of the theory, solutions are presented to illustrate the potential for novel, efficient designs with options including miniature, self-magnetized, reversible, broadband, superconducting, or other advantageous characteristics. New experimental models are showing good conformance to theoretical predictions for this promising alternative circulator design concept. >
Integrated multiple-device IMU system with continuous-time sensing circuitry

This multiple IMU system integrates lateral accelerometers and vertical gyroscopes with signal processing circuits in a post CMOS MEMS process. A direct-coupled continuous-time sensing buffer for MEMS capacitive sensing has a -3dB frequency corner lower than 10Hz. The integration of multiple sensors makes cross-device compensation possible.
The autocatalytic growth model. I. Critical analysis of the conceptual framework.

Because of the important role which the ‘autocatalytic’ or ‘logistic’ equation has played in determining the direction of a good deal of research both in demography and in the study of individual growth phenomena, a critical and comparative evaluation of those leading ideas inRobertson's (1923) book which pertain to this equation and of some of the criticisms levelled against it seemed to be of interest. The present paper shows that, contrary to common belief,Robertson did not really assume that the autocatalytic reactions to which he compared growth processes, took place in closed systems (viz., cells). On the other hand, he does not seem to have found a satisfactory representation of how the growth phenomena of the individual cells in an organism might interact to yield the overall growth of the organism as a whole. Nor is the manner in which he made his equation account for the openness of the individual cells free from possible criticism. An alternative equation is here proposed, which will be discussed in another paper. The properties of the solutions of this equation are such that the autocatalytic theory might never have gained a foothold if this, more realistic, equation would have been the object of the initial studies.
Intricacies of School Relationships and the Well-Being of Arab American Youth: Implications for School Psychologists.

The purpose of this study was to explore the symbolic interaction theory in a sample of Arab American adolescents. Four areas of self-concept were investigated in relation to school environment, including perceived discrimination and social supports. Sixty-one Arab American adolescents (28 males and 33 females) between the ages of 12 and 18 years participated in this survey research study. Participants completed a discrimination questionnaire, the Self-Perception Profile for Adolescents to measure self-concept, and the Social Support Scale for Children to assess perceived social supports. Results were consistent with the symbolic interaction theory in various aspects. Classmate support was significantly related to all domains of self-concept, including physical appearance, athletic competence, behavioral conduct, and close friendship; however, teacher support was only significantly related to behavioral conduct. Experience with discrimination was significantly related to negative perceptions of physical appearance. Implications for school practitioners are discussed as well as directions for future research.
Reply to "Comment on 'Deformation of biological cells in the acoustic field of an oscillating bubble' ".

In the Comment by Choi et al. [Phys. Rev. E 82, 013901 (2010)] on two our articles [Phys. Rev. E 72, 061907 (2005); Phys. Rev. E 79, 021910 (2009)], it is claimed that (a) there is more than one natural frequency associated with the quadruple mode and (b) the quadruple mode shows resonance more closely at the characteristic frequency ${\ensuremath{\omega}}_{\text{T}}/2\ensuremath{\pi}$ than at ${\ensuremath{\omega}}_{\text{K}}/2\ensuremath{\pi}$. In this Reply we would like to provide evidence supporting the conclusions made in our original articles.
Soluble sugar changes in etiolated corn leaf tissue as influenced by red-light treatment

Etiolated corn leaf tissue floated on tap water and irradiated with red light (10 minutes) exhibits changes in monosaccharide content during an 18 hour dark period that follows the light treatment. After 4 hours of darkness, the light effect manifests itself primarily as decrease in glucose and fructose levels, whereas after 18 hours, only a sizeable decrease in fructose level is observed.
Analysis of distribution and virulence genes of pathogenic vibrio in acquatic products

Objective To investigate the distribution of pathogenic vibrios and the virulence genes of V. parahaemolyticus in acquatic products in Shenzhen. Methods From May 2011 to October 2012,416 samples were collected from 5 kinds of acquatic products for isolation and identification of 12 kinds of pathogenic vibrios. Thermostable direct hemolysin( tdh) and tdh-related hemolysin( trh) of V. parahaemolyticus were also detected. Results 1. Seven kinds of pathogenic vibrios,including 457 bacterial strains were isolated from 416 samples,in which 295 V. parahaemolyticus strains( 64. 6%) and 109 V. alginolyticus strains( 23. 9%) were the dominant species. 2. Only 2 V. parahaemolyticus strains were found carrying tdh gene( 0. 7%),while the rest were tdh-trh-. 3. The detection rates of pathogenic vibrios,V. parahaemolyticus and V. alginolyticus were 71. 4%,62. 3% and 26. 2% respectively,and those of pathogenic vibrios( 82. 1%) and V. parahaemolyticus( 72. 1%) were highest in the third season,obviously higher than those in other seasons( P 0. 01). But the detection rate of V. alginolyticus( 42. 3%) in the forth season was obviously higher than that in other seasons( P 0. 01). Conclusion Acquatic products were seriously polluted by pathogenic vibrios. Few V. parahaemolyticus isolates from acquatic products were found carrying virulence gene,pathogenic for human. The routine surveillance should be strengthened on each acquatic product to prevent the occurrence of food-borne diseases.
La vida no es una telenovela: técnica y estética en el teatro de Eduardo Adrianzén

Lo que sorprende en las obras teatrales de Eduardo Adrianzen no es siempre la tematica, aunque, sin duda, los temas que este dramaturgo peruano selecciona nunca se alejan de las controversias religiosas, politicas y personales. No obstante, la manera original en que Adrianzen entreteje sus historias es lo que le permite indagar en los traumas mas profundos de su nacion y de la humanidad. En este trabajo se descifran algunas de las tecnicas teatrales que Adrianzen emplea en una de sus obras mas recientes, Respira, para revelar por que esta y otras obras suyas logran agradar tanto a su publico y siguen ganando premios, aun cuando presentan fuertes condenas de las instituciones religiosas, politicas y sociales e incluso cuandocritican a los mismos receptores que forman el publico que las aprecia.
Monotone co-design problems; or, everything is the same

This paper describes a theory of co-design. The objects of investigation are “design problems”, defined as tuples of “function space”, “implementation space”, and “resources space”, along with the relations that relates implementation to function and implementation to resource usage. “Co-design problems” are defined as the composition of design problems by three operations, roughly equivalent to the concepts of series, parallel, and feedback. “Monotone” design problems are those for which functions are partially ordered and there is an order-preserving map between functions and resources. The main results is that any composition of monotone co-design problem is monotone, and that there exists a systematic procedure to obtain the solution to the composed problem explicitly from the solution of the primitive problems.
Introduction: Type-2 Diabetes

There are over 25 million people in the USA with diabetes, representing 8.3 % of the US population. The worldwide prevalence of diabetes was 347 million in 2010 and it is estimated to rise to 439 million by 2030. This diabetes epidemic can be largely attributed to rise in worldwide obesity [1].
Municipal Government Structure in Wisconsin: Does Form Matter?

This article examines the forms of municipal governments in Wisconsin and their relationship to variables in the areas of socioeconomic, partisanship, election process, decision-making in the governance process, and internal municipal operations. Wisconsin has more mayor-council and mayoral forms with an appointed administrator rather than council-manager forms common in other states. We find that reform in Wisconsin has occurred in all government forms and that most municipalities desiring the managerial results of a professional administration have chosen an adaptation of the mayor-council form. Furthermore, we find that there are few clearly identifiable differences between cities with differing governmental forms.
Salmonella Gives MARCH(ing) Orders to MHC-II

How bacterial pathogens evade adaptive immunity is not well understood. In this issue of Cell Host & Microbe, Bayer-Santos et al. (2016) show that the Salmonella effector protein SteD mediates MARCH8-dependent ubiquitination of class II MHC molecules, thereby inhibiting antigen presentation and limiting T cell responses.
Reporting standards for the imaging-based diagnosis of renal masses on CT and MRI: a national survey of academic abdominal radiologists and urologists.

To define important elements of a structured radiology report of a CT or MRI performed to evaluate an indeterminate renal mass. IRB approval was waived for this multi-site prospective quality improvement study. A 35-question survey investigating elements of a CT or MRI report describing a renal mass was created through an iterative process by the Society of Abdominal Radiology Disease-Focused Panel on renal cell carcinoma. Surveys were distributed to consenting abdominal radiologists and urologists at nine academic institutions. Consensus within and between specialties was defined as ≥70% agreement. Respondent rates were compared with Chi Square test. The response rate was 68% (117/171; 55% [39/71] urologists, 78% [78/100] radiologists). Inter-specialty consensus was that the following were essential: mass size with comparison to prior imaging, mass type (cystic vs. solid), presence of fat, presence of enhancement, and radiologic stage. Urologists were more likely to prefer the Nephrometry score (75% [27/36] vs. 22% [17/76], p < 0.0001), quantitative reporting of enhancement on CT (85% [32/38] vs. 46% [36/77], p < 0.0001), and mass position with respect to the renal polar lines (67% [24/36] vs. 36% [27/76], p = 0.002). There was inter-specialty consensus that the Bosniak classification for cystic masses was preferred. Most urologists (60% [21/35]) preferred management recommendations be omitted for solid masses or Bosniak III–IV cystic masses. Important elements to include in a CT or MRI report of an indeterminate renal mass are critical diagnostic features, the Bosniak classification if relevant, and the most likely specific diagnosis when feasible; including management recommendations is controversial.
Short-term stability and prospective correlates of bullying in middle-school students: an examination of potential demographic, psychosocial, and environmental influences.

Stability and change of bullying over a four-month interval was examined in 516 middle school students (grades 6-8). The stability coefficient was .65 for the entire sample. There was a significant increase in bullying behavior from Time 1 to Time 2 for 6th grade students; no significant change in bullying was found among 7th or 8th graders. For 6th graders, a greater confidence in using non-violent strategies was associated with less bullying at Time 2, while beliefs supportive of violence and misconduct, less positive adult influences, and more negative peer influences were associated with greater likelihood of bullying at Time 2. Higher levels of impulsivity, anger, and depression were also associated with greater levels of bullying over time. Several explanations for the increase in bullying behaviors among 6th graders are discussed and linked to intervention efforts. Language: en
Expansion of Platelets for Transfusion

Abstract Abstract SCI-47 The clinical need for platelets transfusion continues to grow. Platelet units have all the usual concerns with other donor-derived blood products and in addition have concerns over the need to store the platelets at room temperature and of the resulting increased risk of bacterial contamination. Several groups have been able to develop platelets from embryonic stem cells, but achieving significant numbers of pro-platelets and/or platelets from in vitro grown megakaryocytes (Megs) remains elusive. Three sites of thrombopoiesis in vivo have been described: 1) intramedullary, 2) at the medullary/vascular junction, or 3) intrapulmonary from circulating Megs. We investigated whether infusing murine Megs into mice can release a large number of functional platelets both to better understand thrombopoiesis and also to see if such an approach may be an alternative to generating platelets for clinical usage. We show that infused fetal-liver-derived Megs results in 100–200 platelets/Meg. Levels as high as 12% of the total platelets in the recipient mouse were from the infused Megs. These platelets had a delayed presentation, peaking at 90 mins. In spite of these being new platelets, their half-life was only ∼75% of infused platelets. The shortened half-life was not due to the fact that these platelets were fetal in nature in that infused adult-liver-derived Megs had a similar temporal profile. These derived platelets had normal-size distribution, were not activated, and had not been affected by ADAM17 during in vitro culture as determined by surface glycoprotein 1b alpha. Platelet functionality was shown by their incorporation into clots in arterioles and venules in a cremaster laser injury model and in a ferric chloride carotid artery injury model. Using BrdU-labeled Megs we show that most of the Megs are trapped in the lungs with a few also appearing in the splenic red pulp. None were seen in other tissues. Staining with species-specific CD41 antibodies showed that detectable Meg cytoplasm peaked in the pulmonary vasculature at 30 min, and like the nuclei, was mostly gone by 5 hrs. We estimate that only ∼1% of the available pulmonary capillary bed is affected by the infused Megs, and most studied animals survived the infusion of the Megs. These studies support the lungs as a potential site for thrombopoiesis and that in vitro differentiated Megs can be infused directly avoiding the challenge of developing ex vivo technology to release large number of non-activated, but functional platelets. Disclosures: No relevant conflicts of interest to declare.