cssi/SciSciGPT-SciSciNet huggingface dataset:
Concentration of cadmium, copper, lead, and zinc in thirty-five genera of freshwater macroinvertebrates from the Fox River, Illinois and Wisconsin.

The present study is an initial report of the concentration of cadmium, copper, lead, and zinc in 35 genera of aquatic macroinvertebrates collected in the Fox River, Illinois, and Wisconsin.
Performance and Ruminal Fermentation of Dairy Cows Fed Whole Cottonseed with Elevated Concentrations of Free Fatty Acids in the Oil

Abstract Twenty-four lactating Holstein cows were used in an 8-wk completely randomized design trial to examine the effects of feeding whole cottonseed (WCS) with elevated concentrations of free fatty acids (FFA) in the oil on intake and performance. Treatments included WCS with normal concentrations of FFA (6.8%, control) and 2 sources of WCS with elevated FFA [HFFA1 (24.1%) or HFFA2 (22.3%)]. The 2 sources of WCS with elevated FFA differed in that HFFA2 were discolored from being initially stored with excess moisture, which led to heating and deterioration during storage, whereas HFFA1 were normal in appearance and the increase in FFA occurred without heating and visible damage to the WCS. Nutrient concentrations were similar among WCS treatments, which provided 14% of the total dietary dry matter. Dry matter intake tended to be higher for cows fed HFFA2 compared with control and HFFA1. Yield of milk and components was similar among treatments, but milk fat percentage was lower for HFFA1 and HFFA2 compared with control. In a concurrent 3×3 Latin square trial with 6 ruminally canulated Holstein cows, molar proportions of isobutyrate were higher for HFFA2 than control and HFFA1, but no differences were observed in acetate or propionate. Results of these trials indicate that feeding WCS with high concentrations of FFA decreases milk fat percentage but does not alter dry matter intake, milk yield, or concentrations of other components. The minor changes in ruminal fermentation that were observed do not account for the decrease in milk fat percentage.
Determination of two sites of automethylation in bovine erythrocyte protein (D-aspartyl/L-isoaspartyl) carboxyl methyltransferase.

Protein (d-aspartyl/l-isoaspartyl) carboxyl methyltransferase (PCM, E.C. 2.1.1.77) was previously shown to be enzymatically methyl esterified in an autocatalytic manner at altered aspartyl residues; methyl esters are observed in a subpopulation of the enzyme termed theαPCM fraction [Lindquist and McFadden (1994),J. Protein Chem.13, 23–30]. The altered aspartyl sites serving as methyl acceptors inαPCM have now been localized by using proteolytic enzymes and chemical cleavage techniques in combination with matrix-assisted laser desorption/ionization (MALDI) mass spectrometry to identify fragments of the [3H]automethylated enzyme that contain a [3H]methyl ester. Methylation was positively identified at positions Asn188 and Asp217 in the enzyme sequence, a consequence of the spontaneous alteration of these sites tol-isoaspartyl ord-aspartyl sites and their methylation by active PCM molecules. The identification of more than one site of automethylation shows thatαPCM is not a homogeneous population of damaged PCM molecules, but rather a complex population of molecules with a variety of age-altered damage sites.
Parametric studies on the elastic work factor for the CLS specimen

Parametric studies were conducted to see the effects of geometric conditions on the elastic work factor for the CLS specimen. Elastic work factors were calculated in two different ways: numerically using a finite element analysis and analytically from a beam analysis. The results showed that the elastic work factors determined from both methods are comparable. In addition, the results showed that the elastic work factor is not greatly affected by L2L1 but is significantly affected by t1t2.
Honoring James Buchanan

Abstract Honoring James Buchanan is an honor and a privilege. I review the influence of his work on my own research and that of colleagues associated with the Workshop in Political Theory and Policy Analysis. The Calculus of Consent helps to explain the capabilities and limits of citizen self-organization and led to a number of studies in metropolitan areas across the United States. In more recent years, efforts to understand how and when users of a common-pool resource would self-organize to manage resources have also been strongly affected by Buchanan's work.
Gemcitabine plus radiation therapy in the treatment of locally advanced non small-cell lung cancer.

Abstract For stage III non–small-cell lung cancer, there is a need for better systemic, as well as locoregional, control of the tumor. In an attempt to enhance this locoregional control, systemic chemotherapy has been given currently with radiation therapy. Gemcitabine, a novel deoxycytidine analogue, has been shown to be a potent radiosensitizer. This review focuses on the studies using gemcitabine concurrently with radiation therapy in the treatment of locally advanced non–small-cell lung cancer.
Mass spectra of the aminoisoquinolines and 5‐amino‐15N‐isoquinoline

The mass spectra of the isomeric aminoisoquinolines and 5-amino-15N-isoquinoline are reported. In the aminoisoquinolines, the major fragmentation pathway was the loss of two molecules of HCN and a hydrogen atom to give the m/e 89 fragment ion. Two additional pathways culminating with this ion were observed. The mass spectrum of 5-amino-15N-isoquinoline showed a preference of 4 to 1 for loss of HC15N (benzenoid amine group) over HC14N (heterocyclic nitrogen) from the molecular ion.
The unusual fold of herpes simplex virus 1 UL21, a multifunctional tegument protein.

UL21 is a conserved protein in the tegument of alphaherpesviruses and has multiple important albeit poorly understood functions in viral replication and pathogenesis. To provide a roadmap for exploration of the multiple roles of UL21, we determined the crystal structure of its conserved N-terminal domain from herpes simplex virus 1 to 2.0-Å resolution, which revealed a novel sail-like protein fold. Evolutionarily conserved surface patches highlight residues of potential importance for future targeting by mutagenesis.
Angiotensin-converting enzyme inhibitors for systemic hypertension in young and elderly patients.

Abstract Whereas many physicians have been reluctant to treat hypertension in the elderly because of perceived limited benefits and the risk of side effects associated with traditional antihypertensive agents such as diuretics and β blockers, studies and clinical experience have shown that elderly as well as younger patients can benefit from treatment. In recent years, angiotensin-converting enzyme (ACE) inhibitors have been found to be safe and effective in both young and elderly hypertensive patients without many of the adverse effects associated with traditional agents. ACE inhibitors possess characteristics that meet many of the special needs of elderly patients, including reduction of left ventricular mass, lack of metabolic and lipid disturbances, no central nervous system effects, no risk of induction of cardiac failure, and low risk of orthostatic hypotension.
A Study of the Performance of SSL on PDAs

PDAs and smartphones are increasingly being used as handheld computers. Today, their network connectivity and their usages for various tasks over the Internet require privacy and authenticity. In this paper, we conduct a comprehensive and comparative study of the performance of the SSL protocol for PDA and laptop clients, both in WEP secured and open Wi-Fi environments. Unlike previous studies [1], [2], the measurements are at sub-protocol granularity allowing for researchers to consider appropriate optimizations for these resource-constrained devices. Unsurprisingly, we find that SSL handshake costs 3 times more at a PDA client than it does for a laptop client, but surprisingly most of the delay comes from network latency and other PDA architecture issues, not cryptographic computation. This suggests that more effort should be spent in minimizing communication rounds in future cryptographic protocols that will be used by PDAs, even at the cost of more cryptographic operations.
We Ning-ed a Virtual Pre-Workshop: Now What?

In 2009, a group of instruction-minded librarians in Oklahoma added unconference-like elements to their usual workshop structure and agenda to make their workshop more participatory and attendee-driven. The result was a virtual pre-workshop hosted on a Ning social networking site. The virtual pre-workshop enhanced the actual physical workshop in several ways. The group's new challenge: where to host its new pre-workshop format without Ning and how to gear the new format to be more mobile friendly while not excluding non-mobile interested workshop participants.
Determination of Early Stages of Glass Dissolution by pH Titration

The early stages of glass dissolution are marked by rapid changes in pH for leach solutions with low buffer capacity. Consideration of both dissolution reactions and the electrical neutrality requirement allow the calculation of exchanged cation equivalents from the depletion of the H+-ion reservoir. Comparison was made between sodium trisilicate glass, a commercial waste glass (PNL 76–68), and the defense waste reference glass. The released Na+ calculated from the pH curve of sodium trisilicate glass has the expected parabolic dependence on time. Thenuclear waste glasses react with H+ more slowly and the pH - time plots do not have the shape of a titration curve. The equivalents of cations released follow a power law function, the exponent of which depends on initial pH. There are two distinct rate regimes for all glasses with initial fast rates related to consumption of H+ and later, slower rates nearly independent of H+ activity.
First-Time Mothers with a History of Infertility: Their Internalized Pressure to Breastfeed.

Background:The meaning of breastfeeding and breastfeeding experiences has been studied extensively in general and specific populations. However, there is little research about the meaning of breastfeeding and breastfeeding experiences in first-time mothers who were previously infertile.Objective:This article aims to understand the breastfeeding experiences of new mothers with a history of infertility.Methods:Twelve women who were first-time mothers and conceived their infants through fertility treatments were interviewed about their early postpartum experiences as part of a larger phenomenological study. Interview transcripts were reviewed, and data about breastfeeding were extracted and analyzed using thematic analysis.Results:One main theme from the breastfeeding data emerged, “Internalized Pressure to Breastfeed,” with 3 subthemes: “My Only Chance to Breastfeed,” “The One Natural Thing I Should Be Able to Do,” and “Not Breastfeeding Means Failing at Motherhood.” New mothers who have undergone fertility...
A High-Throughput Assay to Identify Small-Molecule Modulators of Alternative Pre-mRNA Splicing

Alternative splicing (AS) is an efficient mechanism that involves the generation of transcriptome and protein diversity from a single gene. Defects in pre–messenger RNA (mRNA) splicing are an impor...
Rapid relaxation inversion of CSAMT data

SUMMARY In this paper an inversion algorithm for controlled-source audio frequency magnetotelluric data is presented. This algorithm combines 2.5-D finite element forward modelling with the concepts of rapid relaxation inversion of magnetotelluric data. The inversion uses the same technique to compute sensitivities as the rapid relaxation inversion, and these approximate sensitivities are validated by comparison with exact 2.5-D sensitivities. The comparison shows that the approximate sensitivities are similar in shape to the exact sensitivities when transmitter‐receiver oVsets are greater than one skin depth in the Earth. The magnitudes of the two sensitivities diVer but the variations with depth are similar. Tests of the algorithm on synthetic data and field data provide promising results.
Monitoring requirements: a case study

In our study of composite systems, we found a class of requirements that could not be guaranteed to hold. Specifically, these requirements required the environment of the overall system to behave in ways that could not be controlled. The best we could do in such cases was to note the assumptions placed on the environment for the requirements to be met, and then monitor the environment at runtime to detect deviations from our assumptions about its behavior. This paper discusses a short example of carrying out this type of monitoring. It introduces three tools to support requirements monitoring: (1) a tool to capture a requirement formally, (2) a tool to translate that requirement into a runtime specification, and (3) a tool to actually do the runtime monitoring.
Vasilii Petrov and The Poetics of Patronage

This article seeks to bridge the gap between sociohistorical and aesthetic readings of Russian occasional verse by arguing that patronage itself can be seen as engendering its own poetics. The author focuses on hitherto unanalyzed features of Vasilii Petrov's lyrics addressed to various patrons. The close readings of Petrov’s odes and epistles call attention to the poet’s coordinating syntax as structuring the subordinative relationships between poet and patron, and articulating discourses of friendship, community, and the public, of civic virtue, and of social and lyric interdependence. The essay ultimately arrives at a definition of the poetics of patronage, in which the poet claims agency without insisting on his autonomy (as would his successors in the Romantic period), and in which the lyric voice relies upon an other, drawing inspiration from conditions of relationship rather than isolation.
Temporal gene expression kinetics for human keratinocytes exposed to hyperthermic stress.

The gene expression kinetics for human cells exposed to hyperthermic stress are not well characterized. In this study, we identified and characterized the genes that are differentially expressed in human epidermal keratinocyte (HEK) cells exposed to hyperthermic stress. In order to obtain temporal gene expression kinetics, we exposed HEK cells to a heat stress protocol (44 °C for 40 min) and used messenger RNA (mRNA) microarrays at 0 h, 4 h and 24 h post-exposure. Bioinformatics software was employed to characterize the chief biological processes and canonical pathways associated with these heat stress genes. The data shows that the genes encoding for heat shock proteins (HSPs) that function to prevent further protein denaturation and aggregation, such as HSP40, HSP70 and HSP105, exhibit maximal expression immediately after exposure to hyperthermic stress. In contrast, the smaller HSPs, such as HSP10 and HSP27, which function in mitochondrial protein biogenesis and cellular adaptation, exhibit maximal expression during the “recovery phase”, roughly 24 h post-exposure. These data suggest that the temporal expression kinetics for each particular HSP appears to correlate with the cellular function that is required at each time point. In summary, these data provide additional insight regarding the expression kinetics of genes that are triggered in HEK cells exposed to hyperthermic stress.
Inhibition of Ca2+ Sparks by Ruthenium Red in Permeabilized Rat Ventricular Myocytes

We have compared the effects of the sarcoplasmic reticulum (SR) Ca(2+) release inhibitor, ruthenium red (RR), on single ryanodine receptor (RyR) channels in lipid bilayers, and on Ca(2+) sparks in permeabilized rat ventricular myocytes. Ruthenium red at 5 microM inhibited the open probability (P(o)) of RyRs approximately 20-50-fold, without significantly affecting the conductance or mean open time of the channel. At the same concentration, RR inhibited the frequency of Ca(2+) sparks in permeabilized myocytes by approximately 10-fold, and reduced the amplitude of large amplitude events (with most probable localization on the line scan) by approximately 3-fold. According to our theoretical simulations, performed with a numerical model of Ca(2+) spark formation, this reduction in Ca(2+) spark amplitude corresponds to an approximately 4-fold decrease in Ca(2+) release flux underlying Ca(2+) sparks. Ruthenium red (5 microM) increased the SR Ca(2+) content by approximately 2-fold (from 151 to 312 micromol/l cytosol). Considering the degree of inhibition of local Ca(2+) release events, the increase in SR Ca(2+) load by RR, and the lack of effects of RR on single RyR open time and conductance, we have estimated that Ca(2+) sparks under normal conditions are generated by openings of at least 10 single RyRs.
Identification of the Veratryl Alcohol Binding Site in Lignin Peroxidase by Site-Directed Mutagenesis

Abstract Site-directed mutagenesis was used to identify the veratryl alcohol binding site of lignin peroxidase. The cDNA encoding isozyme H8 was mutated at Glu146 to both an Ala and a Ser residue. The H8 polypeptide was produced byE. colias inclusion bodies and refolded to yield active enzyme. The wild type recombinant enzyme and the mutants were purified to homogeneity and characterized by steady state kinetics. The kcat is decreased for both mutants of Glu146. The reactivity of mutants (kcat/Km) toward H2O2were not affected. In contrast, the kcat/Km of the mutants for veratryl alcohol were decreased by at least half. The oxidation of guaiacol by these mutants were more significantly affected. These results collectively suggest that E146 plays a central role in the binding of veratryl alcohol by lignin peroxidase.
Stabilization of motor networks

In some cases the most important factor limiting the performance of a distributed control system is not the availability of computational power but rather the availablity of time on a shared communication network for communication between the sensors, the control computer and the actuators. In this paper the author develops a mathematical model describing a class of multivariable control problems of this type and presents an algorithm which can be used to investigate the existence of stabilizing control laws in the presence of communication constraints. The author's model assumes that the communication facilities are to be time-shared according to a pattern which is repeated periodically. The designer has the problem of picking the pattern such that effective control laws can be implemented within the constraints it imposes. If the systems being controlled are linear, there is an affine family of possible closed-loop transition matrices associated with each communication pattern. The selection and implementation of a particular control law which is supported by the given pattern then defines the performance. This approach allows us to put the problem of designing the communication pattern in a form that can be investigated using mathematical programming techniques. In particular one can evaluate the advantages and disadvantages associated with allocating more communication resources to some control loops and less to others.
Genetics, phenotype, and natural history of autosomal dominant cyclic hematopoiesis

Cyclic hematopoiesis, (CH, or cyclic neutropenia) is a rare disease manifested by transient severe neutropenia that recurs approximately every 21 days. The hematologic profile of families with the autosomal dominant form (ADCH) has not been well characterized, and it is unknown if the phenotype is distinct from the more common sporadic congenital or acquired forms of CH. We studied nine ADCH families whose children displayed typical CH blood patterns. Pedigrees confirmed dominant inheritance without evidence of heterogeneity or decreased penetrance; three pedigrees suggested new mutations. Families were Caucasian with exception of one with a Cherokee Native American founder: A wide spectrum of symptom severity, ranging from asymptomatic to life-threatening illness, was observed within families. The phenotype changed with age. Children displayed typical neutrophil cycles with symptoms of mucosal ulceration, lymphadenopathy, and infections. Adults often had fewer and milder chronic neutropenia without distinct cycles. While CH is commonly described as "benign", four children in three of the nine families died of Clostridium or E. coli colitis, documenting the need for urgent evaluation of abdominal pain. Misdiagnosis with other neutropenias was common but can be avoided by serial blood counts in index cases. Genetic counseling requires specific histories and complete blood counts in relatives at risk to assess status regardless of symptoms, especially to determine individuals with new mutations. We propose diagnostic criteria for ADCH in affected children and adults. Recombinant human granulocyte colony-stimulating factor treatment resulted in dramatic improvement of neutropenia and morbidity. The differential diagnosis from other forms of familial neutropenia is reviewed.
BIOREMEDIATION AND LEACHING POTENTIAL OF PENTACHLOROPHENOL (PCP) IN BIODIESEL VERSUS DIESEL CARRIERS

Biodiesel is believed to be more environmentally friendly than petroleum-based diesel when used as a carrier for impregnating wood products with pentachlorophenol (PCP) for decay protection. A 6-mo study was conducted to evaluate bioremediation of PCP in biodiesel vs diesel in soil. Different percentages of biodiesel, diesel, and PCP were mixed with clean soil from a forested site and tested. Samples were taken bimonthly and analyzed for oil and grease, PCP concentration, and microbial enumeration. Soil moisture content was adjusted twice weekly if needed. In addition, toxicity and toxicity characteristic leaching potential were measured at Days 0 and 180. Results showed that with an increase in percentage of biodiesel, there was an increase in degradation of diesel and diesel-amended PCP. The greatest decrease of PCP concentration and toxicity occurred in biodiesel alone by Day 180. Results also showed a significant decrease with time in oil and grease concentration, PCP concentration, and toxicity among different treatments. Based on this study, it appears that the cometabolic effect of biodiesel on micro-organisms could accelerate degradation of PCP in treated wood after disposal.
Quantum Bianchi Identities and Field Equations for General Relativity

Abstract : By invoking the physical symmetry of coordinate invariance for the matter-free gravitational field, the contracted quantum Bianchi identities are derived from a family of Hermitian Lagrangians which are the quantum analogues of the Palatini Lagrangian. It is further shown that these gauge variational techniques yield a set of necessary conditions that determine whether the quantum field equations and contracted Bianchi identities contain purely quantum structures of order (Plancks constant/2pi) squared which possess no quantum analogues. (Author)
Development of color-grapheme synesthesia and its effect on mathematical operations.

SE, a 19-year-old female college student and a color–grapheme synesthete, reported consistent synesthetic experiences (photisms) for digits, and most letters in the Roman and Hebrew alphabets over a 6-month period. Photisms for later-learned Hebrew letters were influenced by those of the Roman alphabet and photisms for auditorily presented words were influenced by the spelling of the words. As hypothesized, in two studies, SE's solution times for addition problems were significantly slower when the colors of the digits in the problems mismatched her synesthetic photisms than when they matched or were in black (p < 0.001), whereas color had no effect on solution times for six female non-synesthetes (aged 19 to 22 years). Implications for learning and cognitive processing are discussed.
Market-Based Model Predictive Control for Large-Scale Information Networks: Completion Time and Value of Solution

There are several important properties of modern software systems. They tend to be large-scale with distributed and component-based architectures. Also, dynamic nature of operating environments leads them to utilize alternative algorithms. However, on the other hand, these properties make it hard to provide appropriate control mechanisms due to the increased complexity. Components are sharing resources and each component can have alternative algorithms. As a result, the behavior of a software system can be controlled through resource allocation, as well as algorithm selection. This novel control problem is worthy of investigation in order to double the benefits of those properties. In this paper, we design a control mechanism for such systems. The quality-of-service we are considering is a product of the value of solution and the time for generating solution for a given problem. We build a mathematical programming model that trades off these two conflicting objectives, and decentralize the model through an auction market. By periodically opening the auction market for each existing system state, a closed-loop policy is formed. Though similar problems can be found in multiprocessor scheduling literature, they have limitations in addressing this control problem. They commonly consider so-called workflow applications in which each component only has to process one task after all of its predecessors complete their tasks. In contrast, a component in the networks under consideration processes multiple tasks in parallel with its successors or predecessors.
The role of the Big Five personality factors in vigilance performance and workload

Using the five-factor personality model, the present study explored the influence of personality factors on sustained attention and perceived workload. Ninety-six college-aged participants were administered a 12 minute vigilance fast event rate task. Following the vigil, participants were asked to first, rate their perceived workload of the task using the NASA-TLX, and then second, complete the NEO-PI-R personality inventory. Traditional measures of hits, false alarms, and reaction times were examined as well as the signal detection indices of perceptual sensitivity and response bias. Extraversion correlated with false alarms (r = 0.181; eta2 = 0.055) and conscientiousness correlated with both false alarms (r = −0.275, eta2 = 0.097) and perceptual sensitivity (r = 0.227, eta2 = 0.052). With regard to perceived workload, neuroticism was related to perceived frustration (r = 0.238, eta2 = 0.057). The findings are discussed in terms of theoretical implications, impact of task parameters, and practical applications. Copyright © 2002 John Wiley & Sons, Ltd.
Beneficial Effects of Early mTORC1 Inhibition after Traumatic Brain Injury.

Abstract The mammalian target of rapamycin complex 1 (mTORC1) signaling pathway mediates many aspects of cell growth and regeneration and is upregulated after moderate to severe traumatic brain injury (TBI). The significance of this increased signaling event for recovery of brain function is presently unclear. We analyzed the time course and cell specificity of mTORC1 signal activation in the mouse hippocampus after moderate controlled cortical impact (CCI) and identified an early neuronal peak of activity that occurs within a few hours after injury. We suppressed this peak activity by a single injection of the mTORC1 inhibitor rapamycin 1 h after CCI and showed that this acute treatment significantly diminishes the extent of neuronal death, astrogliosis, and cognitive impairment 1–3 days after injury. Our findings suggest that the early neuronal peak of mTORC1 activity after TBI is deleterious to brain function, and that acute, early intervention with mTORC1 inhibitors after injury may represent an effec...
Intracavity EO modulation of BBO for a cw all-solid-state deep-UV source

We report the stable generation of cw coherent deep-ultraviolet (UV) radiation at 266 nm, achieved by using a BBO crystal in an external ring resonator for the SHG of a frequency-doubled diode-pumped Nd:YAG laser.
Simultaneous idiopathic sudden sensorineural hearing loss in identical twins.

Two sisters, who are identical twins, had a simultaneous idiopathic sudden hearing loss (ISHL) while listening to loud music at a rock concert. The possibility that their hearing losses, along with the sudden hearing losses related to cordless telephone injuries, are attributable to intracochlear membrane ruptures is discussed. Language: en
To Gender or Not to Gender: Making Sense of Oriki Soki in the Yoruba Naming System

There are different types of names in Yoruba society. Traditionally, Yoruba names were not gender-specific in that both males and females bear the same names. Today however, oriki soki is a particular kind of name that is used in a gender distinctive way. Gendered names do not conform to the logic of Yoruba naming practices, their traditional worldsense and social organization. The apparent gendered nature of oriki soki, then, becomes a curiosity, a puzzle that needs to be explained. This is the goal of my paper.
Detonation propulsion for high pressure environments

One limitation encountered by chemical rocket propulsion in high pressure planetary atmospheres is illustrated by the conflict between the dependence of specific impulse on the ratio of chamber pressure to ambient pressure and the dependence of the motor structural design on the difference between the pressures. This work proposes to resolve the difficulty by employing detonating propellant in which the high pressures necessary for efficient propulsion are developed over a short time and need not be contained statically. Experimental results are presented to substantiate this claim of relatively high performance, together with an analytical development that approximately describes the flow dynamics.
Deformation Induced Dilatations and New Observations on Fracture In Compression in Metallic Glasses at Low Temperatures

Deformation induced dilatations were measured on a Pd-Cu-Si glass by a differential dilatometric method during crystallization. At large pre-strains, these dilatations are large and of the order of 20%. Fracture surfaces of specimens in compression show either the characteristic features of tensile separation or evidence for repeated nucleation of fracture. Rubbing was observed only in a small fraction of a fracture surface.
Development of Emergency Medical Rescue Box for Hazardous Chemical Incident

[Objective]To resolve the problems about detection backward,medical device dispersion in medical support of chemical incident.[Methods]The method of classification and systematic synthesis was adopted to develop portable medical rescue box for hazardous chemical incident.[Results]The developed medical rescue box had 4 functions of sampling and sample storage and transport,rapid detection,detoxification aid and decontamination drugs.It contained solid,liquid sampling and sample storage and transport equipment suitable for on-site emergency needs;It could also provide field checking reagents of volatile poisons,pesticide,rat baits,metal poison,acid and alkali and so on,totally 17 kinds of 5 categories.Special alexipharmic for common poisons and decontamination agent are prepared.[Conclusion]This box can be applied in many field,for its simple operation,strong applicability,and a series of functions.
SALL-E: situated agent for language learning

We describe ongoing research towards building a cognitively plausible system for near one-shot learning of the meanings of attribute words and object names, by grounding them in a sensory model. The system learns incrementally from human demonstrations recorded with the Microsoft Kinect, in which the demonstrator can use unrestricted natural language descriptions. We achieve near-one shot learning of simple objects and attributes by focusing solely on examples where the learning agent is confident, ignoring the rest of the data. We evaluate the system's learning ability by having it generate descriptions of presented objects, including objects it has never seen before, and comparing the system response against collected human descriptions of the same objects. We propose that our method of retrieving object examples with a k-nearest neighbor classifier using Mahalanobis distance corresponds to a cognitively plausible representation of objects. Our initial results show promise for achieving rapid, near one-shot, incremental learning of word meanings.
Objective support for subjective reports of successful inner speech in two people with aphasia.

ABSTRACTPeople with aphasia frequently report being able to say a word correctly in their heads, even if they are unable to say that word aloud. It is difficult to know what is meant by these reports of “successful inner speech”. We probe the experience of successful inner speech in two people with aphasia. We show that these reports are associated with correct overt speech and phonologically related nonword errors, that they relate to word characteristics associated with ease of lexical access but not ease of production, and that they predict whether or not individual words are relearned during anomia treatment. These findings suggest that reports of successful inner speech are meaningful and may be useful to study self-monitoring in aphasia, to better understand anomia, and to predict treatment outcomes. Ultimately, the study of inner speech in people with aphasia could provide critical insights that inform our understanding of normal language.
Outcomes of patients with renal monoclonal immunoglobulin deposition disease

Recent reports suggest that deep hematologic responses to chemotherapy are associated with improved renal outcomes in monoclonal immunoglobulin deposition disease (MIDD). Here we describe the long term outcomes and identify prognostic factors after first line treatment of the largest reported series of patients with MIDD. Between March 1992 and December 2014, 88 patients with MIDD were seen at Mayo Clinic, MN. Renal responses were defined using criteria used for light chain amyloidosis (AL) or those used by the IMWG. Sixty-one (69%) patients had a GFR<30 ml/min/1.73 m2 and 16 (18%) were on renal replacement therapy at diagnosis. The interval between albuminuria or elevation in creatinine and MIDD diagnosis was 12 months suggesting a delay in diagnosis. Thirty-seven patients (42%) had at least a hematologic CR/VGPR. Fifty-three (60%) received an autologous stem cell transplant (ASCT) or proteasome inhibitor (PI)-based treatments. Patients receiving ASCT or PI-based therapies were more likely to achieve at least a hematologic CR/VGPR compared to those receiving other therapies: 66% vs 2%, p<0.0001. Patients that achieved a hematologic CR were more likely to achieve a renal response (53% vs 24%, p=0.001). Five year overall and renal survival for the entire cohort was 67% and 57%, respectively. In multivariate analyses, a baseline GFR<20 ml/min/1.73 m2 and a renal response (using AL or IMWG criteria) were independently predictive of progression to dialysis. This study confirms that deep hematologic responses, best achieved with ASCT or PI-based therapies, are a prerequisite to achieving renal responses. This article is protected by copyright. All rights reserved.
In Defense of Technology

High yields, efficient harvesting, sanitary and rapid processing, high quality distribution and retailing - factors which any country should be proud of. However, for some strange reason these are the very factors that are coming under attack by a vociferous group of individuals who seem bent on destruction of American Food Technology as we know it today. The reasons for the screams of outrage hurled at this Technology escape logical analysis. In this country today we have the potential to be the best fed people in the history of the world with the products at our disposal. Food is now not only nutritious, but it is safe, convenient, of high quality, flavorful, and presented to the consumer at a cost, relative to earnings, which is competitive with any other country in the world at any other time in history, or the present. It is a gross injustice for consumers to have their confidence in the safety and nutritive value of their food supply destroyed without presenting them with all the facts. Perhaps it is necessary to present all the realities of nutrition to the consumer rather than simply to mention nutrients. Perhaps it is time for science and technology to present the facts of an overpopulated-underenergized world to the American consumers who take for granted the food supply at their disposal without an understanding of the technology it involves. It is ludicrous to believe in the natural way. A morally responsible usage of technology, not a profit-at-any-cost technology is the way to solve the hunger problems of the world. This information must be conveyed to the consuming public as a part of a nutrition education if we are to have a well fed and healthy nation without paranoia about its food supply.
Patient-Centered Strategies for Improving Warfarin Management

The need for regular monitoring of warfarin therapeutic therapy is a commonly cited barrier to optimal patient adherence. Alternative warfarin monitoring and management strategies which involve significant patient participation should be considered in select patients and may improve patient adherence and satisfaction with ongoing warfarin therapy.
Exploiting Spatiotemporal Correlation for Wireless Networks Under Interference

This paper starts from an empirical observation on the existence of spatiotemporal correlation among nearby wireless links within short time intervals. The phenomenon due to correlated interference has become pervasive with densely deployed wireless devices, causing potential errors in existing popular metrics built upon the assumption of link independence. To this end, we propose correlated ETX (cETX), which generalizes the widely-adopted ETX to maintain the accuracy under correlated links. To the best of our knowledge, this is the first work to introduce a unified metric embracing both temporal and spatiotemporal correlations. As a generalized metric, the highlight of our work is the broad applicability and effectiveness–extensive evaluations on ZigBee (802.15.4) and Wi-Fi (802.11b/g/n) testbeds deployed in a lab, corridor, and on a bridge reveal that: simply replacing ETX with cETX: 1) cuts down the error by 62.1%–70.2% and 2) saves averages of 22% and 37% communication cost in three unicast and nine broadcast protocols, respectively, under only 0.7% additional overhead.
“It Was Supposed To Be a Onetime Thing”: Experiences of Romantic and Sexual Relationship Typologies Among Young Gay, Bisexual, and Other Men Who Have Sex with Men

Young gay, bisexual, and other men who have sex with men (MSM) are at elevated risk for HIV infection, highlighting the need to understand the elements of prevention and risk associated with their relationships. We employed a phenomenological approach to explore how young MSM become involved in different romantic and sexual experiences. We analyzed 28 semi-structured interviews conducted with young MSM living in Michigan. Using a phenomenological approach, we analyzed the data using an inductive coding strategy and thematic analysis. Participants defined their romantic and sexual interactions with a limited set of partner classifications (e.g., dating, hooking up, friends-with-benefits), but recognized how these classifications were shifting, sometimes unexpectedly so (e.g., a date turning into a hook up and vice versa). Young MSM described relationships in transition that at times defied available typologies or hybridized elements of multiple partner types at once. Based on our analyses, we underscore the need to acknowledge the fluctuating and contextual nature of young MSM's romantic and sexual experiences. We discuss the relevance of our findings in terms of the developmental period of young adulthood and the implications our findings have HIV prevention efforts among young MSM.
Corporate Agriculture and the Exploitation of Life in Portal 2

This article examines the agricultural dimensions of Portal 2 and two of its key paratexts, arguing that the game’s potato motif functions as a satire of industrial agricultural practice, dramatizi...
Built to Grow: Blending Architecture and Biology

The emerging discipline of biomimetics converges biology, chemistry, and engineering to offer a scientific approach to bio-inspiration. It develops methodologies for the in-depth analysis of nature...
Exercise and Emotional Memory: a Systematic Review

Memories are often vividly recalled when experienced during an emotional event (i.e., emotional memory). Exercise has been shown to subserve episodic memory function, but its role in influencing emotional memory is less clear. In this systematic review, we discuss the potential underlying mechanisms that subserve emotional memory and summarize an emerging body of research investigating the effects of exercise on emotional memory. We also highlight recommendations for future work in this emerging field of inquiry.
Deep-Sea Record of Cenozoic Explosive Volcanism in the North Atlantic

Cenozoic explosive volcanism associated with rifting and continued opening of the Norwegian and Greenland Seas has produced two compositional series of silicic tephra. These are preserved in deep-sea sediments. A high-potash and high-alumina series of glasses range from quartz-trachytes to alkali rhyolites and associated comendites. A low-potash series, ranging from ice-landites through dacites and rhyolites, is characterised by low alumina and enriched in Fe and Ca. Both series have been erupted throughout the Cenozoic. The deep-sea cores indicate five apparent episodes of Cenozoic explosive volcanism. The first is a late Paleocene episode recorded in North Sea exploration wells and stems from volcanic activity in the British Isles. A middle Eocene episode is attributed to volcanism on the subaerial Iceland-Faeroes ridge. The middle Oligocene episode coincides with the Kialineq plutonic event in East Greenland. The subsequent lull in rhyolitic explosive volcanism during late Oligocene coincides with minimum activity of the hotspot, low spreading rates and absence of known subaerial volcanic sources. An early to middle Miocene episode is attributed to rejuvenation of the Iceland hotspot and emergence of subaerial Iceland, whereas the Plio-Pleistocene increase in explosive silicic volcanism coincides with rift-jumping between the Icelandic volcanic zones. Ash-fall dispersal in the region is dominated by westerly winds, except during glacial stages, when ice-rafting leads to tephra deposition south of Iceland.
University of Washington Department of Statistics

The modern era of Statistics at the University of Washington (UW) began in 1939 with the arrival of Z. W. (Bill) Birnbaum in the Department of Mathematics. There was but a single course in descriptive statistics. Bill began the process that led to the development of one of the first comprehensive undergraduate statistics programs in the United States.
Volume rendering using the Fourier projection-slice theorem

The Fourier projection-slice theorem states that the inverse transform of a slice extracted from the frequency domain representation of a volume yields a projection of the volume in a direction perpendicular to the slice. This theorem allows the generation of attenuation-only renderings of volume data in O (N 2 log N) time for a volume of size N . In this paper, we show how more realistic renderings can be generated using a class of shading models whose terms are Fourier projections. Models are derived for rendering depth cueing by linear attenuation of variable energy emitters and for rendering directional shading by Lambertian reflection with hemispherical illumination. While the resulting images do not exhibit the occlusion that is characteristic of conventional volume rendering, they provide sufficient depth and shape cues to give a strong illusion that occlusion exists.
A New and Improved Physical Education Setting for Children with ADHD.

Attention deficit hyperactivity disorder (ADHD) is a growing disorder that is rarely addressed in the physical education setting. Through strategies of organization, offering a structured environme...
Techniques for High-Frequency Problems

Techniques based on the method of modal expansions, the Rayleigh-Stevenson expansion in inverse powers of the wavelength, and also the method of moments solution of integral equations are essentially restricted to the analysis of electromagnetic radiating structures which are small in terms of the wavelength. It therefore becomes necessary to employ approximations based on “high-frequency techniques” for performing an efficient analysis of electromagnetic radiating systems that are large in terms of the wavelength.
On-Farm Sulfur Fertilization of Alfalfa and Corn Trials

In the past several years, sulfur (S) deficiency has been showing up more frequently in Iowa fields. Large yield response has especially occurred in corn and alfalfa fields in northeast Iowa. The increase in S response is thought to be partially due to Iowa receiving less S in the rainfall due to more stringent air pollution regulations, less S fertilizer applications, higher crop yields, and less widespread use of manure. Sulfur fertilizer applications can offer yield increases where S deficiencies are present. The objective of these trials was to evaluate potential for S deficiency and yield response in corn and alfalfa to S applications.
Polyacrylonitrile-based nanocomposite fibers: A review of current developments:

This is a state-of-the-art review on essential aspects, types, and applications of polyacrylonitrile-based nanocomposite fibers. Polyacrylonitrile is a commercially important acrylic polymer having...
Blocking of alveolar flapping in speech production: the role of syntactic boundaries and deletion sites

Abstract Experiments were conducted to examine the influence of syntactic boundaries on the operation of a phonological rule in speech production. Groups of ten or more speakers read sentences in which the phonological rule of Alveolar Flapping could be optionally applied across a word boundary. Experiment 1 showed that the occurrence of Flapping is blocked by major syntactic boundaries and that this blocking is not attributable to pausing. Experiment 2 demonstrated that the occurrence of Flapping is markedly reduced when the key word boundary coincides with an embedded clause boundary but is unaffected by boundaries of other phrase types, including noun phrases and verb phrases. Traditional theories of boundary strength, which assign equal weight to boundaries associated with different types of constituents, fail to account for these results. Finally, Experiment 3 showed that Flapping is also reduced in the environment of a syntactic deletion site. The results of these experiments indicate that traditional metrics of boundary strength, as well as linguistic formulations of phonological rules, must be elaborated to recognize the special status of clause boundaries and deletion sites. In speech processing, blocking appears to reflect a constraint on the speaker’s ability to look ahead to consider phonetic information in the word-initial segment following the key word boundary. This information is required to satisfy the conditions under which the phonological rule can apply. The look-ahead capability of the speaker may be limited at word boundaries that coincide with clause boundaries and deletion sites because of the speaker’s need to devote immediate processing capacity to the programming of other prosodic attributes typically accompanying these locations.