cssi/SciSciGPT-SciSciNet huggingface dataset:
Ligand-guided selection of aptamers against T-cell Receptor-cluster of differentiation 3 (TCR-CD3) expressed on Jurkat.E6 cells.

We recently introduced a screening technology termed ligand-guided selection, (LIGS), to selectively identify target-specific aptamers from an evolved cell-SELEX library. Cell-SELEX utilizes a large combinatorial single-stranded oligonucleotide library and progressively selects DNA ligands against whole cells with variable DNA-binding affinities and specificities by repeated rounds of partition and amplification. LIGS exploits the partition step and introduces a secondary, pre-existing high-affinity monoclonal antibody (mAb) ligand to outcompete and elute specific aptamers towards the binding target of the antibody, not the cell. Here, using anti-CD3e mAb against the cluster of differentiation 3 (CD3e), as the guiding ligand against one of the domains of the T-cell Receptor (TCR) complex expressed on Jurkat.E6 cells, we discovered three specific aptamers against TCR complex expressed on an immortalized line of human T lymphocyte cells. In sum, we demonstrate that specific aptamers can be identified utilizing an antibody against a single domain of a multidomain protein complex in their endogenous state with neither post- nor pre-SELEX protein manipulation.
Induced protein degradation: an emerging drug discovery paradigm

Small-molecule drug discovery has traditionally focused on occupancy of a binding site that directly affects protein function, and this approach typically precludes targeting proteins that lack such amenable sites. Furthermore, high systemic drug exposures may be needed to maintain sufficient target inhibition in vivo, increasing the risk of undesirable off-target effects. Induced protein degradation is an alternative approach that is event-driven: upon drug binding, the target protein is tagged for elimination. Emerging technologies based on proteolysis-targeting chimaeras (PROTACs) that exploit cellular quality control machinery to selectively degrade target proteins are attracting considerable attention in the pharmaceutical industry owing to the advantages they could offer over traditional small-molecule strategies. These advantages include the potential to reduce systemic drug exposure, the ability to counteract increased target protein expression that often accompanies inhibition of protein function and the potential ability to target proteins that are not currently therapeutically tractable, such as transcription factors, scaffolding and regulatory proteins.
The Dialectic of Critique, Theory and Method in Developing Feminist Research on Inference

Feminist critiques of rationalism as a masculinist cultural construction, and of logic as a component of this regime of truth, extend to the traditional psychological research on inference as well. This discussion explores issues entailed in reconfiguring the theoretical and empirical study of reasoning on new ground informed by critique, a task that I argue is necessary if feminist theories of logic are to avoid producing new canons through rationalist theorizing and if the study of reasoning is to be rescued from its domination by a rationalist tradition. An illustrative qualitative study of reasoning processes with a design and interpretive framework informed by the above critiques and by feminist perspective on epistemology, is used as a vehicle for exposing the meta-theoretical, theoretical and methodological tensions entailed by this transdisciplinary reconstructive project, the ramifications of critique for method and the theory-data problematic.
Development of Hetero-Core Fiber Optic Tip Tactile Sensors for an Artificial Fingertip

This report describes a compact tactile sensor based on hetero-core fiber optics for imparting tactile perception to an artificial fingertip. The proposed tactile sensor is as small as an optical fiber tip with 250 μm in diameter, and is able to detect soft bending on a hetero-core sensitive portion caused by contact at the end of sensor. From an evaluation test, it was observed that the sensor measures pushing depth in the range from 0.5 mm to 3.0 mm. In addition, it was demonstrated that an artificial fingertip covered with soft silicone rubber skin performs in detecting contact owing to three proposed sensors embedded, each of which has a spatial sensitive region within 4 mm in diameter.
“A Knowing Deep in the Bone”: Cowboy Stoicism and Tragic Heroism in All the Pretty Horses

The fourth and fifth chapters of the study are dedicated to The Border Trilogy, and principally to the evolution of John Grady Cole’s character in the trilogy’s first and third installments, All the Pretty Horses and Cities of the Plain. A close reading of The Border Trilogy supports the thesis that John Grady is McCarthy’s idea of desirable moral exemplarity. An appreciation of the bildungsroman All the Pretty Horses is contingent upon an interpretation of its central protagonist John Grady. Dianne Luce finds that John Grady possesses a “childish’ vision of himself as a romantic hero,” and Charles Bailey styles John Grady as an “anti-hero, futilely acting in a degraded world.” Hillier suggests that John Grady’s heroism is neither immature nor futile, but beneficial, and that his actions provide the best available moral response to the corruption and injustice presented in McCarthy’s fiction. That moral response resembles Aurelian Stoicism, the mode of Stoic practice advanced by the second-century ad Roman Emperor-philosopher Marcus Aurelius. John Grady’s philosophy of life is reaffirmed and refined through his experience of the world’s harsh realities and the evil that men do. By the end of The Border Trilogy’s first installment this anachronistic cowboy emerges with two significant insights. First, John Grady’s Stoic attitude to life is validated and, second, he becomes willing to play the part of a tragic hero, both in accepting that the tragic nature of existence includes beauty and loss, and in demonstrating a preparedness to stand within his own moral center.
Innovative Capacity and the Asset Growth Anomaly

Innovative capacity (IC) is a firm’s ability to produce and commercialize multiple innovations. Expected returns need not fall following asset growth (AG) by high IC firms because investment can generate new growth options. Using patents-based measures for IC, we find that the well-known negative relation between AG and subsequent excess returns (the “asset growth anomaly”) holds only for low IC firms. However, there is no such anomaly for high IC firms and AG is significantly positively related to future excess returns. Moreover, changes in market risk following asset growth are positively related to IC. Therefore, IC plays an important role in the dynamics between AG and returns, and in driving the time-varying market risk of firms.
Identifying decision patterns using Monterey Phoenix

An automated means to identify behavior patterns would enable system developers to gain the benefit of past results in current and future system design. Analysis of decision patterns captures the interactions of human operators, systems, and their interface with the environment. Monterey Phoenix (MP) uses a formal language thereby exploiting the precision of lightweight formal methods as a means to model behaviors across domains, with applicability to the design of systems of systems, operational procedures, communication networks, business processes, and social interaction. This paper illustrates a concept of identifying patterns in a model of a decision process for a surgical procedure and an aviation emergency serving as case analyses. The results support a Bayesian belief network and an analysis of the decision structure. Finding embedded behavior patterns may be used as a means to catalog and classify intrinsic structures or architectures that are useful to system of system developers.
Admission hyperphosphatemia increases the risk of acute kidney injury in hospitalized patients.

Evidence on the association between elevated admission serum phosphate and risk of in-hospital acute kidney injury (AKI) is limited. The aim of this study was to assess the risk of AKI in hospitalized patients stratified by admission serum phosphate level. This is a single-center retrospective study conducted at a tertiary referral hospital. All hospitalized adult patients who had admission phosphate measurement available between January and December 2013 were enrolled. Admission phosphate was categorized into 6 groups ( 4.4 mg/dl was associated with an increased risk of developing AKI with an odds ratio of 1.72 (95% confidence interval 1.20–2.47), whereas admission serum phosphate levels < 4.4 mg/dl were not associated with development of AKI during hospitalization. Elevated admission phosphate is associated with an increased risk for in-hospital AKI.
Between Hyorish and Hyorism: A Korean TV Star and Social Media Activism:

Since her solo debut album in 2003, Lee Hyori, one of the most famous stars in Korea, has kept her name in the limelight as a singer, actress, show host, advertising model, and fashion trendsetter....
Electrophysiologic Devices in Heart Failure

Abstract With the advent of new technology allowing cardiac devices to be smaller in size, the application of both implantable cardioverter defibrillator (ICD) and pacemaker technology in the pediatric patient with heart failure has expanded. The use of ICDs to decrease the incidence of sudden death and cardiac resynchronization therapy pacemakers have now become an important consideration in the treatment of young patients. Devices can also now also be used to quantify a patient's degree of heart failure. Because of the relatively small number of pediatric patients, specific indications are not as well defined as in the adult population. This chapter discusses indications and practical aspects of implantation of pacemakers and ICDs in the pediatric heart failure population.
Sickle cell disease: a malady beyond a hemoglobin defect in cerebrovascular disease.

Introduction: Sickle cell disease (SCD) is a devastating monogenic disorder that presents as a multisystem illness and affects approximately 100,000 individuals in the United States alone. SCD mana...
Principles of Spectral Doppler

Spectral-Doppler ultrasound provides a quantitative visual presentation of blood-flow information. The spectral display is a real-time presentation of Doppler shift vs. time on the vertical and hor...
The Criminalization of Homelessness

Homeless persons have been described as exhibiting impressive rates of psychosocial pathology.1–5 A resurgence of interest in the relationship of mental illness to criminal behavior has been fueled by the substantial and possibly increasing proportions of jail and prison inmates with histories of mental illness and/or homelessness as well as by high rates of arrest and incarceration in homeless populations.6–14 Investigations are being conducted to determine whether mental illness has been “criminalized” as a consequence of deinstitutionalization and the reforms in involuntary commitment laws.11–12,15–18 This chapter examines the relationship among illegal behavior, mental illness, and homelessness through the study of arrests of homeless persons in Baltimore and interprets this relationship in light of historic and contemporary literature.
Hemolysis in PNH

Publisher Summary This chapter highlights the important role that investigations of the hemolysis of paroxysmal nocturnal hemoglobinuria (PNH) have played in defining the molecular basis of the disease. It seems unlikely that additional GPI-anchored erythrocyte complement-regulatory proteins will be identified as deficiency of decay-accelerating factor (DAF), and membrane inhibitor of reactive lysis (MIRL) appears to account entirely for the complement sensitivity of PNH RBC. Conceivably, hemolysis may contribute to the thrombophilia of PNH. Although there is no obvious correlation between the incidence of thromboembolic events and the proportion of glycosylphosphatidylinositol anchored proteins (GPI-AP) deficient erythrocytes, there is a clinical impression that thrombosis occurs more often during hemolytic exacerbations, and this relationship warrants further investigation. In vitro studies suggest that sublytic amounts of complement can induce cellular proliferation. Whether this process is mediated through signaling by GPI-anchored complement-regulatory proteins is not determined, and, it is unclear whether deficiency of DAF and MIRL enhances or obviates this process. Signaling by GPI-AP appears to be an important physiological process, and its relationship to the clonal dominance in PNH needs to be clarified.
Live Attenuated Cholera Vaccines: Flagella and Reactogenicity

The rational design of attenuated Vibrio cholerae strains has been an attractive method for live cholera vaccine development because the major mechanisms of V. cholerae virulence are well defined and convalescence from cholera, the disease it causes, is a strongly immunizing process. After decades of effort to develop safe live attenuated cholera vaccines, however, the appearance of reactogenicity, defined as adverse symptoms in immunized volunteers, has precluded further development of most live vaccine candidates. We now know that V. cholerae flagellar motility is associated with human and animal reactogenicity in early live attenuated cholera vaccines, and recently developed nonflagellated V. cholerae mutant strains have shown great promise as live attenuated vaccines in volunteer studies. This chapter briefly summarizes our current understanding of V. cholerae pathogenesis and describes efforts to use this knowledge to design immunogenical and nonreactogenic live cholera vaccines.
A Real Time Implementation of a 4800 bps Self Excited Vocoder

The purpose of this paper is to describe a fully developed, real-time 4800 bps speech coding system that was designed for use in a nation-wide mobile satellite communications network [1]. The overall goal was to build an inexpensive speech coder capable of producing “near toll quality” coded speech under bursty channel error conditions at bit error rates of approximately 10−3 BER. A form of the self excited vocoder (SEV) was chosen as the speech coding algorithm [2]. Many of the results presented in this paper concern pragmatic issues such as the robust representation of coder parameters, the error protection, and the constraints imposed by a limited hardware environment. A particularly interesting result of this work was that significant subjective speech quality improvements can be achieved under noisy channel conditions by exploiting known properties of the speech coding parameters.
Systematic Review and Meta-analysis of the Impact of Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP) on Cytological Diagnosis and Thyroid Cancer Prevalence

A re-named diagnosis of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) likely impacts the prevalence of thyroid cancer and risk of malignancy in populations based on the established Bethesda System of Reporting Thyroid Cytopathology (TBSRTC). This study was done to investigate the prevalence and cytological distribution of NIFTP. PRISMA guided systematic review was done from a database search of Pubmed, EMBASE, and Medline using the search terms "non-invasive follicular thyroid neoplasm with papillary-like nuclear features", "non-invasive follicular variant of papillary carcinoma", "niftp", and "Bethesda" until November 2018. Original articles with surgically proven diagnoses of NIFTP using strict NIFTP criteria were included. Twenty-nine studies with 1563 cases of NIFTP were included. The pooled prevalence of NIFTP in cases which would be classified previously as the follicular variant of papillary thyroid cancer (FVPTC) and papillary thyroid cancer (PTC) were 43.5% (95% CI 33.5-54.0%) and 4.4% (95% CI 2.0-9.0%) respectively. The pooled TBSRTC distribution of cases diagnosed as NIFTP was: from the non-diagnostic category 3.6% (95% CI 2.4-5.3%), benign 10.0% (95% CI 7.2-13.6%), AUS/FLUS 34.2% (95% CI 28.2-40.8%), FN/SFN 22.7% (95% CI 17.2-29.4%), suspicious for malignancy 22.4% (95% CI 17.7-27.9%), and malignant 7.5% (95% CI 4.2-12.9%). While a significant reduction in FVPTC prevalence is anticipated, a modest reduction of PTC prevalence is also expected with adoption of the NIFTP terminology that would be distributed mainly among lesions classified as indeterminate thyroid nodules. Further studies are needed to identify unique clinical characteristics of these lesions preoperatively.
Voicing Diasporas: Ethnic Radio in Paris and Berlin between Cultural Renewal and Retention, by Nabil Echchaibi: Rowman & Littlefield. 2011. v + pp. 186. ISBN: 978-0-7391-1884-9

(2019). Voicing Diasporas: Ethnic Radio in Paris and Berlin between Cultural Renewal and Retention, by Nabil Echchaibi. Communicatio: Vol. 45, No. 4, pp. 115-117.
Outcomes of an Environmental-Focused, Problem-Solving Intervention for Transition-Age Youth: Project TEAM

Date Presented 04/04/19 Project TEAM teaches transition age youth to identify and resolve environmental barriers to participation. In this quasi-experimental study, youth in Project TEAM sustained increases in problem solving and self-determination, and attained more participation goals than goal setting only. Primary Author and Speaker: Jessica Kramer Additional Authors and Speakers: Christine Helfrich, Ariel Schwartz, ITing Hwang, Preethy Samuel Contributing Authors: Eric Kolaczyk, Aleksandrina Goeva
Use Cases for Owners and Maintainers

Abstract The as-is modeling workflow comprises methods that are needed to convert a set of laser scans or images into a 3D model with geometric information with basic semantics, such as labels of structural components. An as-built model with geometric information is sufficient for measurement only. However, an important group of users of as-is models is owners and maintainers, who often care about more than geometric information of facilities and infrastructure systems. For example, owners and maintainers will ask the following questions: Is a bridge still safe to use? How is the energy performance of a building? When do we need to conduct maintenance of a specific infrastructure? Is there a need for retrofitting? Questions like these cannot be answered directly with the general as-is modeling workflow mainly focusing on the low-level details such as geometric information. It is necessary to define a workflow that addresses the requirements from owners' and maintainers' perspectives. In Section 4.2 , we will present a high-level description of the need for computer vision in infrastructure projects and potential benefits from the perspective of owners and maintainers. In Section 4.3 , we will discuss some issues a general workflow encounters when it is used to model a single asset in an infrastructure management setting. In Section 4.4 , we define the concept of portfolio modeling—which considers the needs of owners and maintainers by extending the general as-is modeling workflow in terms of space, time, and auxiliary information. Starting from Section 4.5 , we will introduce some typical applications from owners and maintainers' perspectives and discuss what extensions (space, time, and auxiliary information) are required and how they are achieved. We will conclude this chapter by outlining guidelines for owners and maintainers, along with potential challenges they may encounter when adopting infrastructure computer vision in their workflows.
Monitoring the effectiveness of daily cleaning practices in an intensive care unit (ICU) setting using an adenosine triphosphate (ATP) bioluminescence assay.

Background The degree to which daily intensive care unit (ICU) cleaning practices impacts bacterial burden is controversial. The study aimed to assess the utility of using adenosine triphosphate (ATP) bioluminescence assays for monitoring effectiveness of daily cleaning in ICU environments. Methods We sampled 364 total samples from 57 patient rooms and 18 common areas in 3 medical ICUs over 12 weeks, before and after routine daily cleaning. Endpoints were ATP levels (relative light units, RLU) and bacterial bioburden (colony forming units, CFU). Results High-touch surfaces in ICU patient rooms and common areas were contaminated before and after cleaning. Routine cleaning significantly reduced bacterial burden in patient rooms (0.14 log10 CFU reduction, P = .008; 0.21 log10 RLU reduction, P 20 CFUs, the proportion of sites with ATP readings >250 RLU was significantly higher than those with ATP readings ≤250 RLU (90.0% vs 10.0%, P Conclusion Routine cleaning significantly reduced bacterial burden on ICU environment surfaces. Although not an alternative to culture methods, ATP assays may be a useful technique to provide rapid feedback on surface cleanliness in ICU settings.
Utilization of New Heart Preservation Technology in the Era of New Organ Allocation and Extended Ischemic Times

Purpose Current ice bag heart preservation technique is associated with wide fluctuations of organ temperature, resulting in sub-optimal preservation and freeze injury. These shortcomings may be particularly impactful with increased ischemic times given increasing retrieval distances associated with new organ allocation. In comparison, the SherpaPakTM Cardiac Transport System is designed for the static hypothermic preservation of donor hearts within a controlled temperature range. This method avoids excess cooling and optimizes preservation during transportation. The purpose of this study is to assess the outcomes of heart transplantation using the static hypothermic preservation (SHP) system as compared with conventional ice bag preservation (IP). Methods Retrospective cohort analysis was performed on adult patients undergoing heart transplantation between 6/30/2018 and 09/02/2019 at a single institution. Donor and recipient baseline characteristics and post-transplant outcomes were compared between patients receiving organs with SHP versus IP for donor heart transport. Patients who underwent multiple organ transplantation were excluded. Results Of 48 consecutive patients undergoing heart transplantation, 20 (41.7%) organs were transported using SHP and 28 (58.3%) using IP. SHP was used for older recipients (61.5 vs 57.5 years, p=0.02), and longer donor heart cold ischemic times (4.35 vs 3.49 hours, Figure1, p=0.018). There were no 30-day mortalities. Despite longer ischemic times, there was no difference in the incidence of any primary graft dysfunction (PGD) (14.3% vs 15.0%, p=1) or severe PGD requiring extracorporeal membrane oxygenation (10.7% vs 5.0%, Table1, p=0.63) between SHP and IP. Conclusion There was no worsening in clinical outcomes with SHP despite longer ischemic times and older recipient ages. With new heart allocation changes, SHP may be beneficial in cases with further transport distances, by mitigating the effect of prolonged ischemic times.
Riots and resources: How food access affects collective violence:

How does food access affect the mobilization of collective violence? The upsurge in rioting in 2008 drew broad attention to the relationship of food and conflict, as scholars and policymakers sough...
Beyond the noun postmodifier: prepositional phrases preceded by nouns in spoken and written academic English.

This study seeks to investigate variation in the use of prepositional phrases following noun phrases in spoken and written academic English. In order to do so, the British Academic Written English (BAWE) Corpus and the British Academic Spoken English (BASE) Corpus were used. The results of this analysis have revealed that there is a specific set of prepositions that control prepositional phrases (of, in, to, for). Nevertheless, contrary to previous studies the findings of this investigation show that prepositional phrases following nouns are more common in spoken registers than written registers. These results might be an indicator of different levels of expertise, or the use of genitives in spoken registers.
On the Effectiveness of Recurrent Neural Networks for Live Modeling of Cyber-Physical Systems

Attention to cyber security of cyber-physical systems (CPS) has led to the development of innovative cyber-resilient methodologies to ensure early detection and mitigation of cyber anomalies and threats. The concept of Digital Twin (DT) has recently emerged as one of the approaches to achieve the objective of resilience. In the approach using DT, a software-based live model of a target CPS is used to continuously monitor, surveil and verify the correctness of the target CPS operation. In this paper, we empirically study the effectiveness of Recurrent Neural Network (RNN)-based models as the basis of DT-based resilience. We uncover the important characteristics of an RNN-based solution with experimentation on a lab-scale Canal Lock CPS emulator with live validations and attack scenarios. For the first time, we demonstrate actual, real-time use of a RNN-based model as a DT for performing live analysis on an operational CPS. Based on the observed results, we highlight the importance of a DT model's training interval, prediction interval and CPS polling interval in the process of anomaly detection. We uncover the limitations in anomaly detection due to real-time synchronization needs of the RNN-based DT. We highlight this uncovered tug of war between synchronization and anomaly detection is inherent in any complex CPS that is monitored and synchronized by relying on the same sensor streams of ground truth for both synchronization as well as anomaly detection.
Fluoroscopic Swallowing Abnormalities in Dysphagic Patients Following Anterior Cervical Spine Surgery.

Objectives:To evaluate the precise objective fluoroscopic abnormalities in persons with dysphagia following anterior cervical spine surgery (ACSS).Methods:129 patients with dysphagia after ACSS wer...
Should I Do This? Factors Influencing the Decision to Raise Grandchildren Among Custodial Grandparents.

Background and objectives Grandparents often step in to raise grandchildren when the middle generation is unavailable or unwilling. Although the consequences of raising grandchildren are well researched, little is known about the factors influencing grandparents' decisions to raise grandchildren. The objectives for this study were to (1) explore the factors that influence decision-making processes among grandparent caregivers, and (2) investigate the extent to which these factors reflect a multi-faceted, dualistic framework. Research design and methods Data were collected from 108 custodial grandparents who answered an open-ended question about their decision to raise grandchildren. Results Content analyses of participants' answers yielded 15 factorial dimensions defined in terms of their negative/push or positive/pull poles, as it related to their decision to raise grandchildren. Chi Square tests were used to examine each dimension to the extent to which elicited frequencies were differentially represented for positive versus negative poles. For 12 dimensions, the negative decisional parameters outweighed those that were positive. Discussion and implications Grandparents report both positive and negative parameters when reflecting on their decision to raise grandchildren. These results call for further research to advance the understanding of the decision-making processes that caregiving grandparents make and the role that they may have on their experiences.
Predicting pressure injury using nursing assessment phenotypes and machine learning methods

Objective Pressure injuries are common and serious complications for hospitalized patients. The pressure injury rate is an important patient safety metric and an indicator of the quality of nursing care. Timely and accurate prediction of pressure injury risk can significantly facilitate early prevention and treatment and avoid adverse outcomes. While many pressure injury risk assessment tools exist, most were developed before there was access to large clinical datasets and advanced statistical methods, limiting their accuracy. In this paper, we describe the development of machine learning-based predictive models, using phenotypes derived from nurse-entered direct patient assessment data. Methods We utilized rich electronic health record data, including full assessment records entered by nurses, from 5 different hospitals affiliated with a large integrated healthcare organization to develop machine learning-based prediction models for pressure injury. Five-fold cross-validation was conducted to evaluate model performance. Results Two pressure injury phenotypes were defined for model development: nonhospital acquired pressure injury (N = 4398) and hospital acquired pressure injury (N = 1767), representing 2 distinct clinical scenarios. A total of 28 clinical features were extracted and multiple machine learning predictive models were developed for both pressure injury phenotypes. The random forest model performed best and achieved an AUC of 0.92 and 0.94 in 2 test sets, respectively. The Glasgow coma scale, a nurse-entered level of consciousness measurement, was the most important feature for both groups. Conclusions This model accurately predicts pressure injury development and, if validated externally, may be helpful in widespread pressure injury prevention.
Laboratory millimeter and submillimeter spectrum of HOC

The J = 1→2, 2→3, and 3→4 rotational transitions of the molecular ion HOC^+ have been measured in the laboratory at frequencies from 178 to 358 GHz. The data should permit astronomers to confirm the recent possible sighting of the J = 1→0 transition of HOC^+ in Sgr B2 at 89.5 GHz.
Acute kidney injury incidence, recovery, and long-term kidney outcomes among hospitalized patients with COVID-19 and influenza.

Introduction Acute kidney injury (AKI) is a common complication in patients with severe COVID-19. We sought to compare the AKI incidence and outcomes among patients hospitalized with COVID-19 and with influenza. Methods This was a retrospective cohort study of patients with COVID-19 hospitalized between March and May 2020 and historical controls hospitalized with influenza A or B between January 2017 and December 2019 within a large health care system. Cox proportional hazards models were used to compare the risk of AKI during hospitalization. Secondary outcomes included AKI recovery, mortality, new-onset chronic kidney disease (CKD), and ≥25% estimated glomerular filtration rate (eGFR) decline. Results A total of 2425 patients were included; 1091 (45%) had COVID-19, and 1334 (55%) had influenza. The overall AKI rate was 23% and 13% in patients with COVID-19 and influenza, respectively. Compared with influenza, hospitalized patients with COVID-19 had an increased risk of developing AKI (adjusted hazard ratio [aHR] = 1.58; 95% confidence interval [CI], 1.29–1.94). Patients with AKI were more likely to die in the hospital when infected with COVID-19 versus influenza (aHR = 3.55; 95% CI, 2.11–5.97). Among patients surviving to hospital discharge, the rate of AKI recovery was lower in patients with COVID-19 (aHR = 0.47; 95% CI, 0.36–0.62); however, among patients followed for ≥90 days, new-onset CKD (aHR = 1.24; 95% CI, 0.86–1.78) and ≥25% eGFR decline at the last follow-up (aHR = 1.36, 95% CI, 0.97–1.90) were not significantly different between the cohorts. Conclusion AKI and mortality rates are significantly higher in patients with COVID-19 than influenza; however, kidney recovery among long-term survivors appears to be similar.
Emotional intelligence among Nigerian adolescents the role of training

The study investigated the influence of training on emotional intelligence of adolescents in Jos South LGA of Plateau State Forty eight adolescents from two secondary schools Sunnah High School and TCNN Secondary School were used for the study An experimental design was used in the study with participants in the experimental group and in the control group The treatment group participated in six sessions of training involving intensive training in emotional social intelligence skills acquisition for one month The Wong and Law Emotional Intelligence Scale WLEIS were used to measure emotional intelligence The hypothesis tested showed that there was a significant effect of training on emotional intelligence of adolescents with those in the experimental group scoring higher on emotional intelligence Because Training was found to be effective in improving the emotional intelligence of adolescents in secondary schools participating in this study Curriculum developers were recommended to incorporate emotional intelligence training into the school curriculum in schools which will help in the development of a sane society
Correlation of Eggshell Strength and Salmonella Enteritidis Contamination of Commercial Shell Eggs

Shell quality has been identified as a heritable trait that can be manipulated by genetic selection. Previous research has concluded that many methods of determining shell quality produce variable results. With the development of newer, more precise measuring technologies, shell strength can now be assessed in a consistent, objective fashion. A research project was conducted to determine what role shell strength might play in affecting external Salmonella Enteritidis contamination of egg contents. Visibly clean eggs were collected from an in-line shell egg-processing facility at the accumulator. Eggs were inoculated by dipping in a concentrated suspension of nalidixic acid-resistant Salmonella Enteritidis. After storage, eggs were assessed for shell strength and both external and internal Salmonella Enteritidis contamination. In the first study, there was a significant difference (P < 0.05) in shell strength among the three replicates. No differences between treatments were found for shell strength or Salmonella Enteritidis contamination of contents. In the second study, there were no replicate differences for any of the monitored factors. When rinsate and content samples were enriched, 100% of the rinsates were positive for Salmonella Enteritidis. No content samples were shown to be contaminated with Salmonella Enteritidis during direct plating, but 3 to 5% of the samples from each replicate were positive after enrichment. Correlation analysis of the results from each study found only weak correlations between shell strength and Salmonella Enteritidis contamination on eggshell surface or contents. Within the range of shell strengths recorded in this study, the correlation analysis suggests that shell strength does not play a major role in Salmonella Enteritidis contamination. Further work with eggs that represent a greater range of shell strengths could provide a clearer indication of the interaction of shell strength and Salmonella Enteritidis contamination.
Muscular Multiculturalism: Bodies, Space, and Living Together in Andrea Levy's Small Island

This article argues that Andrea Levy's 2004 novel, Small Island, and its interrogation of the politics of British multiculturalism imagines a model of multicultural encounter that prioritizes the emplaced and embodied experience. Playing off of David Cameron's call for a “muscular liberalism,” I suggest that Levy imagines a “muscular multiculturalism” whereby, through difficult, corporeal interactions, the inhabitants of a shared space learn to live together.
On the Chvátal-Erdős triangle game

Given a graph $G$ and positive integers $n$ and $q$, let ${\bf G}(G;n,q)$ be the game played on the edges of the complete graph $K_n$ in which the two players, Maker and Breaker, alternately claim $1$ and $q$ edges, respectively. Maker's goal is to occupy all edges in some copy of $G$; Breaker tries to prevent it. In their seminal paper on positional games, Chvatal and Erdős proved that in the game ${\bf G}(K_3;n,q)$, Maker has a winning strategy if $q
Final Scientific Report: 'Processing and Hydrogeological Analysis of the Data of the November 2003 Flood Event in the Reno River Closed at Pracchia'

An interesting case study for the implementation of the model was identified by the DISTART research group in the Northern Apennine Mountains, as requested by the LAMPIT research group. The identified watershed is the most upstream part of Reno river basin, at the closure section of Pracchia, located in the Tuscan part of the Reno watershed, close to the border with the Regione Emilia Romagna. Following an analysis of the rainfall and stream flow data collected from 2002 and 2007, the flood event that took place at the beginning of November 2003 (days 7-9) was identified as one of the most severe meteorological events in the whole observation period. The rainfall event was characterized by high rainfall intensities for several hours over the entire northern Apennine area and it corresponded to a significant flood hydrograph at the Pracchia cross-section. As required by the LAMPIT and CIRA, the following data, needed for the implementation of both hydrological/hydraulic and meteorological modelling, were collected, processed and delivered to either the CIRA or the LAMPIT research groups by the end of July 2009. In addition to the collection and processing of the above data, the DISTART group performed the research activities needed for issuing the following products (delivered to the LAMPIT research group on the 30th September 2009): the spatially distributed hourly rainfall fields on the basis of the ground raingauge data, for each hour from 0.00, 7 November 2003 to 23.00, 9 November 2003, that is the total (or gross) hourly rainfall fields (in a matrix form, following the standards required by the LAMPIT research group, that is for cells of 20 m x 20 m) over the watershed area; an estimate of the spatio-temporal distribution of the net rainfall, that is of the part of the gross rainfall that actually becomes surface runoff (or overland flow). Net rainfall is obtained is subtracting from the gross rainfall the water losses ascribed to: interception by the vegetation, depression storage (or surface retention) and infiltration. A net rainfall map, over the watershed (plus buffer) area, was computed for each hour from 0.00, 7 November 2003 to 23.00, 9 November 2003.
An asymptotic analysis of acoustic scattering by nearly rigid or soft targets

Publisher Summary This chapter discusses an asymptotic analysis of acoustic scattering by nearly rigid or soft targets. The qualitative features of the field scattered by a penetrable acoustic target, insonified by a time periodic incident wave, depends on a number of factors. Among them are the frequency of the incident wave: the densities and indicies of refraction of the target (ρ t and n t respectively) and the surrounding acoustic fluid (ρ a and n a , respectively), and the shape of the target. When the incident frequency is bounded away from all the “ in vacuo ” or resonant frequencies of the target, then the scattered field is given essentially by the field scattered either by the rigid or by the soft target, depending on whether ɛ is small or large.
The push toward grid regionalization in open access transmission systems

Summary form only given. This presentation focuses on the major thrusts in the establishment of new independent transmission management structures that will control transmission operations and planning uniformly in large geographic regions. These so-called RTOs or regional transmission organizations are pushing strongly toward the regionalization of the grid.
Swine manure char as an adsorbent for mitigation of p-cresol

There is a significant interest in synthesizing inexpensive adsorbents for mitigating pollutants emitted from animal agriculture industry such as p-cresol. Biochar, a byproduct obtained from thermochemical biomass processing is one such source of adsorbent materials. However, presently there is not enough quantitative information on adsorption of p-cresol on biochar. Hence, the goal of this research is to investigate swine manure char as an inexpensive adsorbent for removal of p-cresol from an aqueous system. Swine manure was gasified for 15 min at 704°C to obtain gasified manure char. The char was characterized using physical and chemical techniques. Batch experiments were performed in duplicates at 25°C, 35°C, and 45°C to determine the adsorption isotherms and kinetics. Results indicated that gasification enhanced surface area and acid value of manure from 11.42 ± 0.20 to 49.12 ± 0.79 m2 g−1 and 7.81 ± 0.05 to 8.57 ± 0.01, respectively. The enhanced basicity of the resultant char promoted chemisorption of p-cresol on char surface with maximum adsorption capacities of 7.63 mg g−1 (25°C), 14.99 mg g−1 (35°C), and 14.84 mg g−1 (45°C). Langmuir and Freundlich models suggested that adsorption of p-cresol on char was favorable. Kinetic analysis of the data also confirmed chemisorption of p-cresol while the analysis of transport processes suggested that internal diffusion of p-cresol within the pores was the rate-limiting step. Use of biochar as an adsorbent for p-cresol will add value to gasification byproducts and simultaneously reduce water and air pollution associated with swine farming operations. © 2014 American Institute of Chemical Engineers Environ Prog, 34: 125–131, 2015
Fibromuscular Dysplasia Leading to Spontaneous Coronary Artery Dissection with Sudden Cardiac Arrest.

A 30-year-old previously healthy female, who was six-week postpartum, experienced sudden collapse and tonic-clonic seizure. Emergency medicine services arrived at the scene and the patient was found to be in ventricular fibrillation. Advanced cardiovascular life support (ACLS) was initiated with return of spontaneous circulation. Afterwards, her initial EKG showed atrial fibrillation with rapid ventricular rate, ST elevation in leads II, III, and aVF, and ST depression in V2–V4. She was transferred to a tertiary care hospital where emergent angiogram was performed revealing obstruction of blood flow in the proximal and mid right coronary artery (RCA). A hazy and irregularly contoured appearance of the RCA was consistent with diagnosis of fibromuscular dysplasia. Subsequently, intravascular ultrasonogram (IVUS) was performed which confirmed the diagnosis of RCA dissection. Successful revascularization of the RCA was performed using two bare mental stents. After a complicated course in hospital, she was discharged in stable condition and did very well overall.
Cholecystokinin is not a major hormonal regulator of lower esophageal sphincter pressure

Abstract Although injection of cholecystokinin can reduce resting lower esophageal sphincter pressure, the physiological significance of this finding has not been established. The purpose of this double-blind crossover study was to determine the effect of physiological plasma levels of cholecystokinin on resting lower esophageal sphincter pressure. Eighteen normal male volunteers were studied on two separate days. Following a 20-minute baseline period, subjects received infusions of saline or synthetic cholecystokinin-8 at increasing rates. Basal plasma cholecystokinin levels averaged 1.3 ± 0.2 pmol/L (mean ± SE) and increased to levels of 7.4 ± 0.9 pmol/L, 12.1 ± 2.4 pmol/L, and 23.1 ± 3.8 pmol/L during cholecystokinin infusion rates of 21,42, and 84 pmol/min, respectively. Lower esophageal sphincter pressure was recorded continuously with a sleeved catheter. Basal lower esophageal sphincter pressure averaged 19.9 mm Hg and did not change with the first infusion, which produced physiological peak postprandial plasma levels of cholecystokinin. Lower esophageal sphincter pressure declined only during the infusions that produced plasma cholecystokinin levels two to four times greater than normal peak postprandial levels. Since infusion of cholecystokinin to levels that reproduce physiological blood levels does not significantly decrease lower esophageal sphincter pressure, it was concluded that cholecystokinin is not a major hormonal regulator of lower esophageal sphincter relaxation.
Cloud computing and management processes

Cloud computing represents a modern concept in the area of informatics, consisting of a distributed assembly of computational services, applications, access to information and data storage, in such a manner that the user does not need to know the placement and physical configuration of the systems supplying theses services. There is no assimilated Romanian translation for the term cloud computing. Cloud platforms allow systems to provide levels of high-availability that are impossible to reach using private networks, except when massive investments are made. A first and major advantage of the cloud is that a reduced quantity of resources can be acquired and if necessary the structure can be expanded.
Experience with 200 Renal Artery Reconstructive Procedures for Hypertension or Renal Failure

Renovascular hypertension is the most common form of reversible hypertension. An analysis of 200 renal artery reconstructive procedures identified atherosclerosis as the arteriopathic lesion in 83 per cent of cases and fibromuscular hyperplasia in 13 per cent of cases. Bilateral renovascular disease was found in 31 per cent of cases. Renal arteriography is the most significant factor in the diagnostic evaluation of the hypertensive subject. Bypass graft and patch-graft angioplasty were the most commonly employed principles of renal artery reconstruction in this series. The occlusive process in the renal artery produced a pressure gradient exceeding 25 mm. Hg in 76 per cent of cases. The average period of observation following operation in these 200 patients was 1.6 years, ranging between 3 months and 5 years. Eighty per cent of patients are now normotensive. The primary goal of operation in 12 patients was reversal of renal failure due to severe bilateral renal artery occlusive disease. Disappearance of a...
Isolation and structure of bryostatins 14 and 15

Abstract Further investigation of constituents from the marine bryozoan Bugula neritina employing new 1,000 kg recollections from the Gulf of Mexico and Eastern Pacific Ocean (California) has led to isolation and structural determination of two previously undetected members of the bryostatin (1-13) series, bryostatins 14 (14) and 15 (15). Structural analyses were conducted primarily with high field (400 MHz) NMR and high resolution mass spectral techniques. Both new bryostatins significantly inhibited growth of the P388 lymphocytic leukemia.
Efficient lookup table-based adaptive baseband predistortion architecture for memoryless nonlinearity

Digital predistortion is an effective means to compensate for the nonlinear effects of a memoryless system. In case of a cellular transmitter, a digital baseband predistorter can mitigate the undesirable nonlinear effects along the signal chain, particularly the nonlinear impairments in the radiofrequency (RF) amplifiers. To be practically feasible, the implementation complexity of the predistorter must be minimized so that it becomes a cost-effective solution for the resource-limited wireless handset. This paper proposes optimizations that facilitate the design of a low-cost high-performance adaptive digital baseband predistorter for memoryless systems. A comparative performance analysis of the amplitude and power lookup table (LUT) indexing schemes is presented. An optimized low-complexity amplitude approximation and its hardware synthesis results are also studied. An efficient LUT predistorter training algorithm that combines the fast convergence speed of the normalized leastmean squares (NLMSs) with a small hardware footprint is proposed. Results of fixed-point simulations based on the measured nonlinear characteristics of an RF amplifier are presented.
A Salmon Research Laboratory

(1953). A Salmon Research Laboratory. The Progressive Fish-Culturist: Vol. 15, No. 2, pp. 78-79.