cssi/SciSciGPT-SciSciNet huggingface dataset:
Computer Graphics Applications in Geometry: “Because the Light is Better Over Here”

The theme New Directions in Applied and Computational Mathematics gives all of us who think of ourselves as “pure mathematicians” the chance to reexamine the changes that have taken place in our understanding of that term as a result of the new directions which have appeared in our lifetimes. I have always thought of myself as a geometer, as soon as I realized that it was possible to think of different subspecies of mathematician, and I can make the case today that there will be major differences in the way we do geometry and the way we present our insights to our students and colleagues because of the dramatic developments in visualization capabilities in the form of interactive computer graphics. One effect of these developments is that I find myself revising my concept of the differences between pure and applied mathematics. A virture of a symposium such as this, honoring a wide-ranging mathematician like Gail Young, is that we speakers are encouraged to be introspective about these changes in our careers, and of course that encourages in turn a certain anecdotal style.
Highly accelerated parallel imaging methods for localized massive array coils: comparison using 64-channel phased-array data

Massive parallel phased-array systems with 32, 64, or more receive channels have potential to achieve high scan time saving for parallel MRI. In the past decade, a number of parallel MRI methods have been proposed including SENSE, SMASH, PILS, GRAPPA, SPACE-RIP, SEA, and other methods. In this work, we investigate the optimality of four reconstruction methods for parallel imaging with massive localized linear phased-array coils. In particular, the artifact power, SNR, and scan efficiency of different methods are systematically compared and analyzed. The studies are based on real MR data collected using a 64-channel system for 2-D MR imaging. The results show that the auto-PILS method and the improved GRAPPA method provide the best SNR and minimal artifact. In addition, the auto-PILS method is most efficient in scan time reduction. Interestingly, SMASH is not optimal for use with the highly localized coils with coil width on the same order as the voxel size.
Independently updated views

Independently updated views (IUVs) are updated versions of a relational view. Unlike traditional views, updating an IUV changes only that IUV and not the underlying database. Updates to an IUV are stored in a differential table (DT) and incorporated when the IUV is accessed. There is no restriction on the type of query used to define the IUV. Applications of IUVs include alternative scenarios for decision support, local updating of distributed snapshots, and CAD versioning. IUVs allow versions to be defined on dynamic databases. This may cause inconsistencies because both the IUV and the base tables on which the IUV is defined can be updated independently of one another. We introduce "overlapping updates" that cause such inconsistencies and present algorithms for their detection and resolution using timestamps. These algorithms do not impose additional overhead on the database and require only the modification of the DT. A performance analysis indicates that the cost of querying IUVs is reasonable for a wide range of queries, views, and access strategies. We also consider a materialized implementation of IUVs. Materialized IUVs do not require a DT, relying instead on additional system columns for operation codes and timestamps. Results suggest a mix of implementation strategies for different types of IUV applications, depending on the frequency and nature of queries on the IUVs, the IUV sizes, and how actively the base tables are updated.
Pharmacokinetics and bioavailability of zidovudine and its glucuronidated metabolite in patients with human immunodeficiency virus infection and hepatic disease (AIDS Clinical Trials Group protocol 062).

The pharmacokinetics of zidovudine (ZDV) are established in patients with various stages of human immunodeficiency virus (HIV) disease. This study was conducted to determine the pharmacokinetic parameters of ZDV in patients with asymptomatic HIV infection and liver disease. HIV-infected volunteers with normal renal function were stratified according to the severity of liver disease (seven of eight were classified as mild). Each subject received a single intravenous dose of ZDV (120 mg) on the first day, followed by a single oral dose of ZDV (200 mg) on the second day. Blood samples were obtained over a 8-h collection interval, and concentrations of ZDV and its glucuronidated metabolite (GZDV) were determined by high-performance liquid chromatography. The following pharmacokinetic parameters were obtained after oral administration of ZDV to HIV-infected patients with mild hepatic disease; these values were compared with previously reported data in healthy volunteers. The area under the curve (AUC) (1,670 +/- 192 ng.h/ml), maximum concentration of drug in serum (1,751 +/- 180 ng/ml), and half-life (2.04 +/- 0.38 h) of ZDV were increased, while the apparent oral clearance (1.57 +/- 0.31 liter/h/kg of body weight) was decreased; AUC (7,685 +/- 1,222 ng.h/ml) and maximum concentration of drug in serum (5,220 +/- 1,350 ng/ml) of GZDV and the AUC ratio of GZDV to ZDV (2.79 +/- 0.43) after oral administration were decreased. ZDV absolute bioavailability was 0.75 +/- 0.15 in HIV-infected patients with hepatic disease. Although the ZDV apparent oral clearance was not impaired as significantly as in patients with biopsy-proven cirrhosis, our results suggest that ZDV, could accumulate in HIV-infected patients with mild hepatic disease because of impaired formation of GZDV. Patients with mild hepatic disease may require dosage adjustment to avoid accumulation of ZDV after extended therapy.
Mechanical analyses of listric normal faulting with emphasis on seismicity assessment

Abstract Mechanical analyses of listric normal faults analogous to a model of Yucca Mountain (Nevada) faults were conducted to examine the possibility and consequences of slip on such faults. Specific consequences such as distribution of ground-motion amplitudes and possibility of triggered slip on other faults and fractures within the zone of influence associated with slip on listric faults were investigated. Slip on listric faults is likely to initiate at depth on steep fault segments and propagate upwards towards the ground surface, and downward and laterally along the low-angle detachment. We present argument that low-angle normal faults are credible sources of seismicity but the seismic risk presented by such faults is smaller than the risk associated with steeply dipping faults because of reduced rupture propagation rates on low-angle faults. Slip on a listric fault is likely to trigger slip on steeply dipping faults within its hangingwall. Such triggered slip tends to originate at shallow depths (less than 1 km). The shape of listric faults has considerable effect on the distribution of ground-motion amplitudes associated with fault slip, because of the tendency for energy focusing due to the curvature of the fault. As a result, ground-motion amplitudes at a distant location may exceed those at locations closer to the fault; furthermore, although ground-motion amplitudes generally decrease with increasing depth below the ground surface, there are several situations for which the amplitude at depth exceeds the amplitude on the ground surface at the same map location.
Rank-based tests for interactions in a two-way design when there are ties

Among the non-parametric approaches to defining and testing the hypothesis of no interactions in a two-way design, the method by Patel and Hoel is appealing because it is a function of the ranks and therefore invariant under monotonic increasing transformations of the data, and it does not require the assumption of no main effects for the approach to be valid. Recently, Wilcox compared three different methods for implementing their method, each method differing in how the appropriate standard error is estimated. In terms of Type I errors, only one of the methods gave satisfactory results in simulations, but it assumes there are no tied values. Cliff has considered the problem of tied values in detail, and his results are easily extended to the problem considered by Wilcox. This paper describes this extension and compares it to the method recommended by Wilcox.
Examining Values and Beliefs About Teaching Diverse Students: Understanding the Challenges for Teacher Education

This paper presents empirical evidence regarding the capacity of teacher education programs to influence the values and beliefs of those who enroll in them and offers insight into the conditions th...
Reliability and validity of mobile teledermatology in human immunodeficiency virus-positive patients in Botswana: a pilot study.

Importance Mobile teledermatology may increase access to care. Objective To determine whether mobile teledermatology in human immunodeficiency virus (HIV)–positive patients in Gaborone, Botswana, was reliable and produced valid assessments compared with face-to-face dermatologic consultations. Design, Setting, and Participants Cross-sectional study conducted in outpatient clinics and public inpatient settings in Botswana for 76 HIV-positive patients 18 years and older with a skin or mucosal condition that had not been evaluated by a dermatologist. Main Outcomes and Measures We calculated the κ coefficient for diagnosis, diagnostic category, and management for test-retest and interrater reliability. We also determined sensitivity and specificity for each diagnosis. Results The κ coefficient for test-retest reliability ranged from 0.47 (95% CI, 0.35 to 0.59) to 0.78 (0.67 to 0.88) for the primary diagnosis, 0.29 (0.18 to 0.42) to 0.73 (0.61 to 0.84) for diagnostic category, and 0.17 (−0.01 to 0.36) to 0.54 (0.38 to 0.70) for management. The κ coefficient for interrater reliability ranged from 0.41 (95% CI, 0.31 to 0.52) to 0.51 (0.41 to 0.61) for the primary diagnosis, 0.22 (0.14 to 0.31) to 0.43 (0.34 to 0.53) for diagnostic category, and 0.08 (0.02 to 0.15) to 0.12 (0.01 to 0.23) for management. Sensitivity and specificity for the top 10 diagnoses varied from 0 to 0.88 and 0.84 to 1.00, respectively. Conclusions and Relevance Our results suggest that while the use of mobile teledermatology technology in HIV-positive patients in Botswana has significant potential for improving access to care, additional work is needed to improve the reliability and validity of this technology on a larger scale in this population.
The impact of self-construals on social anxiety: a gender-specific interaction

Abstract Ninety-seven American-born, Caucasian participants completed self-report questionnaires in a study examining the impact of gender, gender role orientation and independent and interdependent self-construals upon social anxiety. Three significant findings emerged: gender membership did not predict social anxiety severity, identification with a traditionally masculine gender role orientation decreased risk for social anxiety, and self-construals predicted levels of social anxiety differentially in men and women. In men, interdependence and independence predicted levels of social anxiety positively and negatively, respectively, while these patterns of association were reversed in women. Implications of the results are discussed in terms of the role of gender-specific cultural expectations and self-discrepancies in social anxiety.
Histologic healing responses in human vertical lesions following the use of osseous allografts and barrier membranes

Abstract 4 vertical lesions at 3 teeth in 2 volunteer adults with severe periodontitis were treated by open surgical debridement, osseous allografts and barrier membranes. Roots were notched at both gingival margins and the deepest visible calculus and flaps were sutured coronally. Patients were placed on 0.12% chlorhexidine gluconate 2 × daily post-surgery, and blocks were harvested 5 to 6 weeks after surgery. No abnormal clinical responses were noted during the observation period. In the 4 sites, the average preoperative pocket depth was 9.4 mm; the post-operative pocket depth averaged 4.9 mm, recession averaged 0.9 mm and gain in clinical closure averaged 3.6 mm. Histologically, new cementum measured coronally-apically at the treated sites varied from 0.0 mm to 1.7 mm, with an average of 1.1 mm. Osseous remodelling and crestal osteogenesis were seen in association with cemen to genesis. The newly deposited cementum showed insertion of functional oriented fibers. New attachment was present within 2 out of 4 calculus notches in this sample.
Recycling of Poly(phenylene ether) Blends

The effects of postindustry recycling of polymer blends composed of poly(phenylene ether) (PPE) on the properties of the PPE blends were investigated by simulated recycling with multiple molding cycles. Two compositions with different concentrations of PPE were reprocessed with an injection-molding machine. Mechanical, thermal, rheological, and morphological characterizations were carried out on as-produced and reprocessed samples to examine the influence of the number of molding cycles on the two specific PPE blends. Efforts were made to determine the effect of each molding cycle on the specific properties of the two PPE blends, including the Elastic (E), modulus, stress at break, strain at break, multiaxial impact, and melt viscosity. The results are discussed in detail. The retention of the properties correlated well with the unperturbed morphology of the compositions before and after recycling, as observed by transmission electron microscopy analyses on fractured tensile samples. However, more in-depth microanalyses are required to identify the effect of recycling on the individual components present in the studied compositions. In this study, we aimed to establish structure–property relations upon recycling using several characterization techniques. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Molecular species composition of rat liver phospholipids by ESI-MS/MS: the effect of chromatography.

Using electrospray ionization tandem mass spectrometry (ESI-MS/MS) this study shows that the loss of glycerophospholipid (GPL) after chromatography was unevenly distributed across the GPL molecular species. Both TLC and HPLC caused a preferential loss of GPL with 0 to 3 double bonds: 20% and 7.2% for choline glycerophosphates (PC) and 19.7% and 7.5% for ethanolamine glycerophosphates (PE), respectively. A consequence of these losses was that GPLs containing fatty acids with four or more double bonds had a greater contribution to the total after chromatography. ESI-MS/MS analysis also showed that PC molecular species with four or more double bonds migrated at the front of the TLC band of PCs. GPLs extracted from TLC plates occasionally contained PCs that were smaller than those in the original extract. These low molecular mass PCs were easily reduced to alcohols and formed derivatives with 2,4-dinitrophenylhydrazine, suggesting that aldehydes were generated by the oxidation of unsaturated fatty acids. Directly analyzing lipid extracts by ESI-MS/MS without preliminary chromatographic separation gives an accurate distribution of GPL molecular species in lipid mixtures. However, the ionization of the phospholipids in the electrospray jet maximized at relatively low concentrations of GPL. There was a linear response between phospholipid mass and ion intensity for concentrations around 1–2 nmol/ml for both PC and PE. The total ion intensity continued to increase with concentrations above 1–2 nmol/ml, but the response was non-linear. —DeLong, C. J., P. R. S. Baker, M. Samuel, Z. Cui, and M. J. Thomas. Molecular species composition of rat liver phospholipids by ESI-MS/MS: the effect of chromatography. J. Lipid Res. 2001. 42: 1959–1968.
Probing the adhesive footprints of mytilus Californianus byssus

California mussels Mytilus californianus owe their tenacity to a holdfast known as the byssus, a fibrous extracellular structure that ends distally in flattened adhesive plaques. The "footprints" of freshly secreted plaques deposited onto glass coverslips were shown by matrix-assisted laser desorption ionization time of flight mass spectrometry to consist chiefly of proteins ranging in mass from 5200 to 6700 Da. These proteins, variants of a family known as mcfp3 (M. californianus foot protein 3), were purified from acetic acid/urea extracts of plaques and foot tissue. Mcfp3 appears to sort into fast and slow electrophoretic variants. Both are rich in Gly and Asn and exhibit post-translational hydroxylation of Tyr and Arg to Dopa and 4-hydroxyarginine, respectively, with the fast variant containing more than twice as much Lys + Arg. Both the slow and fast variants were partially sequenced from the N terminus, and the complete sequences of 12 variants were deduced from cDNA using degenerate oligonucleotides, PCR, and rapid amplification of cDNA ends. Mcfp3s are highly polar molecules and contain up to 28 mol % Dopa, which remains intact and may be crucial for adhesion to metal and mineral surfaces.
A CSO search for l-C3H+: detection in the Orion Bar PDR

The results of a Caltech Submillimeter Observatory (CSO) search for l-C_3H^+, first detected by Pety et al. (2012) in observations toward the Horsehead photodissociation region (PDR), are presented. A total of 39 sources were observed in the 1 mm window. Evidence of emission from l-C_3H^+ is found in only a single source - the Orion Bar PDR region, which shows a rotational temperature of 178(13) K and a column density of 7(2) × 10^(11) cm^(−2). In the remaining sources, upper limits of ~10^(11) − 10^(13) cm^(−2) are found. These results are discussed in the context of guiding future observational searches for this species.
Optimization of Diesel Engine Operating Parameters Using Neural Networks

Neural networks are useful tools for optimization studies since they are very fast, so that while capturing the accuracy of multi-dimensional CFD calculations or experimental data, they can be run numerous times as required by many optimization techniques. This paper describes how a set of neural networks trained on a multi-dimensional CFD code to predict pressure, temperature, heat flux, torque and emissions, have been used by a genetic algorithm in combination with a hill-climbing type algorithm to optimize operating parameters of a diesel engine over the entire speed-torque map of the engine. The optimized parameters are mass of fuel injected per cycle, shape of the injection profile for dual split injection, start of injection, EGR level and boost pressure. These have been optimized for minimum emissions. Another set of neural networks have been trained to predict the optimized parameters, based on the speed-torque point of the engine. These networks can be thought of as 'engine maps' and have been used to simulate the emissions of the engine over the FTP heavy duty diesel cycle. Improvements resulting from the optimization have been recorded. The entire process of getting optimized parameters for an engine, starting from raw engine data or CFD results is capable of being automated and has been shown to take a reasonably small amount of computational time.
Abstract 368: Insulin Promotes Hypoxic Vascular Injury in Insulin Resistance

Clinical studies targeting aggressive lowering of blood glucose in type 2 diabetes (T2DM) by exogenous insulin failed to show cardiovascular protection, but paradoxically increased cardiovascular m...
Characterization of genetically engineered mouse models carrying Col2a1-cre-induced deletions of Lrp5 and/or Lrp6

Mice carrying Collagen2a1-cre-mediated deletions of Lrp5 and/or Lrp6 were created and characterized. Mice lacking either gene alone were viable and fertile with normal knee morphology. Mice in which both Lrp5 and Lrp6 were conditionally ablated via Collagen2a1-cre-mediated deletion displayed severe defects in skeletal development during embryogenesis. In addition, adult mice carrying Collagen2a1-cre-mediated deletions of Lrp5 and/or Lrp6 displayed low bone mass suggesting that the Collagen2a1-cre transgene was active in cells that subsequently differentiated into osteoblasts. In both embryonic skeletal development and establishment of adult bone mass, Lrp5 and Lrp6 carry out redundant functions.
Analysis of a Microplasma Fuel Reformer with a Carbon Dioxide Decomposition Reaction

Microplasmas have become increasingly attractive for activating chemical reactions because of their advantages over conventional plasma technology and catalytic processes. Advantages of reduced power requirements, atmospheric pressure operation, portability, and the circumventing of catalyst issues have made microplasmas a fascinating alternative for hydrocarbon reforming. Through the course of previous work, these microplasma reactors have displayed process and plasma variability that make characterizing the microplasma reactor challenging. In the current study, 24 experiments were run using 16 different microplasma reactors, with carbon dioxide as the only reactant. Carbon dioxide decomposition was chosen because it provides a simple experimental reaction environment that eliminates the need for a carrier gas and reduces the number of undesirable products. Carbon dioxide decomposition also has potential application for greenhouse gas mitigation. For example, an array of microplasma devices on the exhaus...
Nanophotonic Luminescent Solar Concentrators

This talk will discuss recent results in creating nanophotonic luminescent solar concentrators. Here we combine tunable quantum dot luminophores with photonic designs to improve the concentration efficiency of LSCs and study light propagation.
An Analysis of Law Culture That "A Prince Who Commits A Crime Will Endure the Same Penalty as A Plebeian Does

The concept of law culture that "A prince who commits a crime will endure the same penalty as a plebeian does" was originated in the self sufficient small scale peasant economy in ancient Chinese society, in the political system of "centralization of state power" and in "the recognition of plebeian interests" on the part of Confucianists and "the same penalty to criminals no matter who they are" advocated by Legalists. Such a concept meant to maintain the interests and the reign of the monarch rather than the basic rights of plebeians. The right of immunity enjoyed by a monarch and later given to bureaucrats and aristocrats prevented the ideal concept from coming into reality.
Perspectives on Children’s Fraction Knowledge

The separation of the study of whole numbers and fractions is historical and contributes to the legendary difficulty children experience in the learning of fractions that inspired Davis et al. (1993) to comment that “the learning of fractions is not only very hard, it is, in the broader scheme of things, a dismal failure” (p. 63). I cite Davis et al. not because I believe that the teaching and learning of fractions is by necessity a dismal failure, but rather to accentuate the historical difficulties children experience in learning fractions in mathematics education. These difficulties are quite unsettling because they have been known for a long time. For example, in his famous study on the grade placement of arithmetical topics, Washburne (1930, p. 669) reported that a mental age level of 9 years should be attained by children if at least three out of four of them are to make the very modest mastery represented by a retention test score of 80% on the meaning of “nongrouping” fractions. But, in the case of “grouping” fractions, the analogous mental age was 11 years 7 months.1
Surface superconductivity at high temperatures

The possibility that surface superconductivity of the Ginzburg type might occur at high temperatures is investigated. The most likely effect is seen to be surface ordering brought about by resonance coupling through the impurity surface states. A mechanism is described by which the localized coherence which this requires can occur, giving transition temperatures orders of magnitudes higher than any now known.
Demographics Shaping Learning Communities: A Collective Case Study of Career

Career academies emerged as part an education reform effort and, like smaller schools within schools, have drawn attention for their success in motivating at risk students to stay in school through graduation. This article draws on career academies in the southern, border region of California, not to reinforce the value of the career academy concept as an educational practice, but as a field of investigation for how public schools either change or reproduce patterns of stratification, depending on their demographics. Based on interviews and student performance data from nine career academy programs embedded within large urban high schools in San Diego, California, the study produced a typology as a framework of analysis. In this article, a case study of an Inclusive-&-Interconnecting career academy will be contrasted with an Autonomous-&-Exclusive one, in order to examine how the demographics of the school appear to be related to reinforcement of, or conversely a breaking with, socially reproductive patterns and practices, thus either upholding, or compromising the original intentions of educational reforms designed to reverse stratification and uneven representation.
Writing and Experimentation

In this chapter, we present and consider the performance of writing as a creative pedagogical practice that can work toward moments of social justice. Using the language of performance, we discuss the pedagogical value of writing for experimentation, rehearsal, and enactment of new ideas.
Value of pharmacy-related bulletin board services as a drug information resource.

OBJECTIVE To orient pharmacists to bulletin board services (BBSs) as a source of drug information, and to provide information concerning equipment, services, and resources, as well as examples of systems that are used frequently. DISCUSSION Pharmacy-related BBSs allow pharmacists who have no experience with a new formulation or therapeutic use for a medication to obtain information from those who have such experience. CONCLUSIONS As computers become increasingly common in both hospital and community pharmacies and because many BBSs provide free access to newsletters and databases for drug information, pharmacy-related BBSs represent an easy, inexpensive method to share ideas and obtain information on medication use.
Do automated program repair techniques repair hard and important bugs

Automated program repair techniques use a buggy program and a partial specification (typically a test suite) to produce a program variant that satisfies the specification. While prior work has studied patch quality [10, 11] and maintainability [2], it has not examined whether automated repair techniques are capable of repairing defects that developers consider important or that are hard for developers to repair manually. This paper tackles those questions.
Golf as Meaningful Play. A Philosophical Guide

Golf as Meaningful Play is the second volume of the Lexington Books ‘Studies in Philosophy of Sport’ series edited by Shawn Klein. In the book, Tomas Schmid draws on both Aristotle’s virtue ethics ...
Association of Author Gender With Sex Bias in Surgical Research.

Importance Previous studies demonstrate sex bias in surgical research. Female participants and investigators are underrepresented in surgical scientific research. Objectives To describe the distribution of male and female authors in 5 general-interest surgery journals, assess the association of author gender with sex bias, and explore whether investigators benefit from performing sex-inclusion research. Design, Setting, and Participants For this bibliometric analysis, data were abstracted from 1921 original, peer-reviewed articles published from January 1, 2011, through December 31, 2012, in Annals of Surgery , American Journal of Surgery , JAMA Surgery , The Journal of Surgical Research , and Surgery. Excluded articles pertained to a sex-specific disease or did not report the number of study participants. An additional 119 articles contained gender-ambiguous author names and were omitted. Data were analyzed from April to June 2017. Main Outcomes and Measures Male and female first and senior authors, number of female and male participants in each study, surgical specialty, and number of citations received per article. Results Of the 3604 authors of 1802 articles included in this study, 2791 first and senior authors (77.4%) were male and 813 (22.6%) were female. The prevalence of male and female authors was consistent across all 5 journals and among clinical and basic science research. Articles by female authors included a higher median number of female study participants compared with their male counterparts (27.5 vs 16.0; P = .01), but sex matched the inclusion of participants less frequently (36% vs 45%; P = .001). No sex-based differences occurred between male and female authors in reporting, statistical analysis, and discussion of the data or in the number of citations received. Compared with studies that did not report, analyze, or discuss data by sex, studies that performed sex-specific data reporting yielded a mean of 2.8 more citations (95% CI, 1.2-4.4; P = .001); those that performed statistical analysis, a mean of 3.5 more citations (95% CI, 1.8-5.1; P = .001); and those that discussed the data, a mean of 2.6 more citations (95% CI, 0.7-4.5; P = .001). Articles with a higher percentage of sex matching of participants also received more citations, with an increase of 1 citation per 4.8% (95% CI, 2.0%-7.7%; P = .001) increase in percentage of sex matching. Conclusions and Relevance Sex bias in surgical research is prevalent among male and female authors; however, female authors included proportionally more female participants in their studies compared with male authors. Notably, studies that addressed sex bias were rewarded by the scientific community with increased citations of their published work.
EFFECTIVENESS OF THE IMPLEMENTATION OF COOPERATIVE LEARNING MODEL OF STAD TYPE WITH SAVI-CTL APPROACH IN MATHEMATICS LEARNING TO CLASS VII STUDENTS AT SMPN 2 BONTONOMPO SELATAN IN GOWA DISTRICT

The study aims at describing the effectiveness of cooperative learning model of STAD type with SAVI-CTL approach in Mathematics learning to Class VII students at SMPN 2 Bontonompo Selatan in Gowa District. The study is pre-experiment research. The populations were all class VII students at SMPN 2 Bontonompo Selatan in Gowa District. The sample was class VII.C as the experiment class chosen by employing simple random sampling technique. Data collections were students’ learning result, students’ activities during the learning process, and students’ responses on the implementation of learning model. Data were analyzed by using descriptive analysis and inferensial analysis. The results of the study reveal that the students’ learning result in Mathematics is in high category with the mean 81.17 and deviation standard 6.64, the classical completeness level is 88%, the mean of normalized gain of learning result is in high category, students’ activities in learning are in Tended to be Active category with the mean 3.28, and students’ responses on the implementation of cooperative model of STAD type with SAVI-CTL approach is in positive category with the mean 3.55. In general, the conclusion is the cooperative model of STAD type with SAVI-CTL approach is effective to be applied in Mathematics learning to Class VII Students at SMPN 2 Bontonompo Selatan in Gowa District.
Closed form models for dwell point locations with turnover-based storage assignment policy

This study investigates where an idle storage-retrieval device should dwell (locate) to minimise the expected response time of its next transaction for both an automated storage/retrieval system (AS/RS) and an automated storage carousel (ASC). A review of the relevant literature showed that previous attempts to obtain the dwell point location only considered a randomised storage assignment policy. This research proposes that under a myriad of operating conditions, the problem can be formulated as a p-median location problem on a tree network to incorporate the turnover-based storage assignment policy.
Corrosion assessment of Ti-6Al-4V fabricated using laser powder-bed fusion additive manufacturing

Abstract We describe the interfacial characteristics of a Ti-6Al-4V alloy fabricated using laser powder-bed fusion (L-PBF) upon exposure to a corrosive environment and tribocorrosion conditions. Electrochemical techniques in both the time and frequency domains demonstrated a correlation between the manufacturing process parameters and corrosion properties, and a titanium oxide passive layer produced specific semiconductor n-type properties. The influence of the microstructure on the titanium oxide passive layer was revealed by comparing L-PBF parts with a traditionally manufactured Ti-6Al-4V alloy in Ringer's simulated body solution. Tribocorrosion characterization reflected the endurance of the surface oxide when the process parameters were adjusted. In addition, wearing simultaneously reflected the mechanical condition as the surface repassivate. The production of fragmentation film during wear caused accumulation of the corrosion product and demonstrated the effect of aggressive ions on the chemical and mechanical properties of the passivation film.
An investigation of sepsis surveillance and emergency treatment on patient mortality outcomes: An observational cohort study.

Objective To determine the prevalence of initiating the sepsis 3-h bundle of care and estimate effects of bundle completion on risk-adjusted mortality among emergency department (ED) patients screened-in by electronic surveillance. Materials and methods This was a multiple center observational cohort study conducted in 2016. The study population was comprised of patients screened-in by St. John Sepsis Surveillance Agent within 4 h of ED arrival, had a sepsis bundle initiated, and admitted to hospital. We built multivariable logistic regression models to estimate impact of a 3-h bundle completed within 3 h of arrival on mortality outcomes. Results Approximately 3% ED patients were screened-in by electronic surveillance within 4 h of arrival and admitted to hospital. Nearly 7 in 10 (69%) patients had a bundle initiated, with most bundles completed within 3 h of arrival. The fully-adjusted risk model achieved good discrimination on mortality outcomes [area under the receiver operating characteristic 0.82, 95% confidence interval (CI) 0.79-0.85] and estimated 34% reduced mortality risk among patients with a bundle completed within 3 h of arrival compared to non-completers. Discussion The sepsis bundle is an effective intervention for many vulnerable patients, and likely to be completed within 3 h after arrival when electronic surveillance with reliable alert notifications are integrated into clinical workflow. Beginning at triage, the platform and sepsis program enables identification and management of patients with greater precision, and increases the odds of good outcomes. Conclusion Sepsis surveillance and clinical decision support accelerate accurate recognition and stratification of patients, and facilitate timely delivery of health care.
Cybernetics Is an Antihumanism. Technoscience and the Rebellion Against the Human Condition

There is no science that does not rest on a metaphysics, though typically it remains concealed. It is the responsibility of the philosopher to uncover this metaphysics, and then to subject it to criticism. What I have tried to show is that cybernetics, far from being the apotheosis of Cartesian humanism, as Heidegger supposed, actually represented a crucial moment in its demystification, and indeed in its deconstruction.
Does Dynein Influence the Non-Mendelian Inheritance of Chromosome 17 Homologs in Male Mice?

Abstract Natural populations of the various subspecies of Mus musculus possess two homologous forms of the proximal one-third of chromosome 17, a region known as the t-complex. About 80–90% of mice carry a wild-type (+) form, while a substantial minority contains t-haplotypes (t), members of a family of region-spanning inversion polymorphisms recently descended from a common ancestor. Interestingly, male +/t-heterozygotes transmit t en bloc to 95–99% of their progeny, while males carrying two t-haplotype (t/t) are invariably sterile. Approximately one-quarter of a century ago, Lyon proposed that two to three cis/trans-acting t-complex distorter factors (Tcd-1, Tcd-2, Tcd-3) operating on a cis-acting t-responder gene product were responsible for the observed non-Mendelian transmission of t-chromosomes (transmission ratio distortion (TRD)) and that homozygosity for these Tcds was the basis of the observed sterility. Subsequent gene mapping and cloning studies linked two mutant dynein light chains to the Tcd-1 and Tcd-3 loci and an altered dynein heavy chain to the Tcd-2 locus. Evidence that TRD is caused by defective sperm flagellar function in roughly one-half of the caudal sperm population from +/t-males raised the possibility that the mutant axonemal dynein components were the Tcds. Here, I discuss whether, in light of new evidence, the dynein subunits linked to the Tcd loci retain any or all of their original mystique as genes that affect the non-Mendelian inheritance of mouse chromosome 17.
Evaluating Telepresence Robots in the Field

Most robotic systems are usually used and evaluated in laboratory setting for a limited period of time. The limitation of lab evaluation is that it does not take into account the different challenges imposed by the fielding of robotic solutions into real contexts. Our current work evaluates a robotic telepresence platform to be used with elderly people. This paper describes our effort toward a comprehensive, ecological and longitudinal evaluation of such robots. Specifically, the paper highlights open points related to the transition from laboratory to real world settings. It first discusses some results from a short term evaluation performed in Italy, obtained by interviewing 44 healthcare workers as possible clients (people connecting to the robot) and 10 older adults as possible end users (people receiving visits through the robot). It then describes a complete evaluation plan designed for a long term assessment also dwelling on the initial application of such methodology to test sites, finally it introduces some technical features that could enable a more robust real world deployment.
Critical Error 10 Not Preparing Enough

fter his work at Los Alamos during the war, Richard Feynman began teaching at Cornell. During that first semester, he became depressed at how little research he was doing. He claimed to feel “tired”
Discoveries of Protein S - and N -Homocysteinylation

In early studies, Hcy was identified in plasma and urine from patients with CBS or MTHFR deficiency [290, 291], but was undetectable in normal individuals. What was surprising in those studies was the inability to detect Hcy in tissues from CBS- or MTHFR-deficient patients [292, 293]. This suggested that a significant quantity of Hcy must have escaped detection by the conventional methods of amino acid analysis [294], possibly because Hcy was bound to protein via disulfide bonds and removed during the deproteinization step.
Climate Change, Climate Engineering, and the ‘Global Poor’: What Does Justice Require?

In recent work, Joshua Horton and David Keith argue on distributive and consequentialist grounds that research into solar radiation management (SRM) geoengineering is justified because the resultin...
Phenotypic features of patients with complex regional pain syndrome compared with those with neuropathic pain

Introduction We hypothesized that patients with complex regional pain syndrome (CRPS) would describe a more negative pain phenotype including higher pain severity, more neuropathic pain descriptors, more centralized pain symptoms, poorer physical function, and more affective distress when compared with patients with neuropathic pain of the extremities not meeting CRPS criteria. Materials and methods This was a retrospective cross-sectional study conducted at a tertiary pain center. The sample included 212 patients who met Budapest Criteria for CRPS and 175 patients with neuropathic pain of the extremities who did not meet criteria. All patients completed a packet of questionnaires before their initial visit containing validated outcome measures assessing pain severity, pain interference, physical functioning, depression, anxiety, and catastrophizing. Results Patients with CRPS reported higher physical disability (p=0.022) and more neuropathic pain symptoms (p=0.002) than patients not meeting CRPS criteria, but the groups did not otherwise differ significantly. There were no significant differences in pain severity or affective distress, despite power analyses suggesting the ability to detect small to medium effect sizes (d=0.29; w=0.14). Subanalyses of differences in neuropathic pain symptoms revealed that patients with CRPS, compared with patients not meeting CRPS criteria, were more likely to report pain with light touch (p=0.003), sudden pain attacks (p=0.003), pain with cold or heat (p=0.002), sensation of numbness (p=0.042), and pain with slight pressure (p=0.018). Discussion Counter to our hypothesis, the present study suggests that patients with CRPS do not have a worse clinical phenotype compared with patients not meeting CRPS criteria, with the exception of higher physical disability and more neuropathic pain symptoms. This corresponds to recent evidence that patients with CRPS are similar to other patient populations with chronic pain.
Analysis of anisotropic rotary diffusion models for fiber orientation

Abstract Anisotropic rotary diffusion (ARD) has proved useful for modeling fiber orientation in molding of discontinuous-fiber composites. A number of ARD models have been proposed, but it has been difficult to compare models or understand the effects of each model’s parameters. We cast the framework laid out by Phelps and Tucker (JNNFM, 2009) into a new form that reveals the scalar magnitude and tensorial “direction” of rotary diffusion for each model. Existing models are compared in this framework. We illustrate the parameter values needed by each model to fit a steady-state orientation in simple shear flow and briefly discuss the behavior of the fitted models in planar elongational flow. The transient overshoot of flow-direction orientation at startup of simple shear varies considerably; however, the transient of the fourth-order component that governs shear stress is very similar among ARD models. Maps of achievable orientation states in steady simple shear are presented; these maps provide first-order estimates of the model parameters needed to fit experimental data.
Continuously-Tunable Substrate Integrated Waveguide Bandpass Filter Actuated by Liquid Metal

An elegant continuously-tunable bandpass filter with a wide tuning range based on liquid metal is presented. The filter is realized using square substrate integrated waveguide cavity resonators, capacitively loaded with liquid metal posts at the center of the resonators. By changing the height of the liquid metal posts, and hence altering the loading capacitances, the resonant frequencies of the resonators are continuously tuned. To prove the concept, a second order bandpass filter is realized and measured. Measurements confirm the wide range tunability of the filter. This demonstrates that liquid-metal, continuous tuning is a promising mechanism for future frequency-agile filter applications.
Multicenter, Prospective, Phase II and Biomarker Study of High-Dose Bevacizumab as Induction Therapy in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannoma.

PURPOSEBevacizumab treatment at 7.5 mg/kg every 3 weeks results in improved hearing in approximately 35%-40% of patients with neurofibromatosis type 2 (NF2) and progressive vestibular schwannomas (...
Natural Mating Systems and Controlled Mating

Abstract Aside from selection, controlled mating is another powerful tool available to the plant breeder for making desirable genetic changes to plant populations. Unlike animals, plants do not select mating partners through behavior. Natural mating in plants is accomplished by altering the morphology and chemistry of flowers and flower parts to increase the probability of targeted mating alternatives. Certain floral modifications promote self-pollination while others favor cross-pollination. An overlay of mating type on parsimony analysis of plant taxa reveals that reproductive biology is highly mutable over short periods of evolutionary time. Surveys of floral structure and function within species often reveal diversity, suggesting that floral biology is a highly mutable feature of plants. Over the past 25 years, the implication of the MADS-box family of transcription factors has been discovered to be profoundly implicated in plant flower development. By understanding the molecular bases of floral development, plant breeders will be able to craft methods to manipulate underlying genes to change floral function and mating system in desirable ways. One fascinating strategy that plants have developed to enhance cross-pollination is self-incompatibility (SI). Two different forms of SI have been found in plants based on the determination of pollen SI phenotype by the parental sporophyte genotype or gametophyte haplotype. Methods have been crafted by plant breeders to avert SI during the breeding phase and to utilize SI for large-scale controlled mating. Certain plant taxa have been discovered in which the embryos within seeds are of maternal sporophyte origin, not the sexual fusion of gametes; known as apomixis. This phenomenon may be obligate or reversible either environmentally or according to genotype. By controlling apomixis, plant breeders can reap benefits that are difficult or impossible via obligate sexual reproduction. The genetic control of developmental processes that lead to other floral modifications that promote cross-pollination is also increasingly well understood. For example, the genetic changes that accompany the evolutionary transition from hermaphrodity to dioecy have been elucidated, and the underlying molecular biology of male sterility has been progressively revealed. This knowledge will empower the plant breeder to incorporate specific genes into breeding programs that will culminate in desirable reproductive outcomes. At present, plant breeders relay mostly on relatively mundane strategies to alter mating system. Advances in our understanding of floral development and reproduction at the molecular level will, however, provide more opportunities to use genomics for controlled mating in the future.