cssi/SciSciGPT-SciSciNet huggingface dataset:
Children's Conceptions of Career Choice and Attainment: Model Development.

This article describes a model of children’s conceptions of two key career development processes: career choice and career attainment. The model of children’s understanding of career choice and attainment was constructed with developmental research and theory into children’s understanding of allied phenomena such as their understanding of illness, violence, and ethnicity. The proposed model articulates aspects of career development during childhood that have not been addressed in extant vocational models. Six levels of development of vocational reasoning are described, ranging from magical, association-based thinking to reasoning that involves the dynamic interaction of influences at the individual, relational, and systemic levels.
Value of accuracy in linear systems

A connection between precision and downside expected lost revenue for linear systems was developed in previous work. Having the value of precision and accuracy in economic terms helps justify the upgrade of instrumentation and/or the increase in corrective maintenance repair rate. The connection between accuracy and economic value is extended in this article to the case where biases are present and in the context of existing corrective maintenance capabilities. © 2005 American Institute of Chemical Engineers AIChE J, 2006
An Adaptive Media-Aware Retransmission Timeout Estimation Method for Low-Delay Packet Video

Time-constrained error recovery is an integral component of reliable low-delay video applications. Regardless of the error-control method adopted by the application, unacknowledged or missing packets must be quickly identified as lost or delayed, so that necessary actions can be taken by the server/client on time. Historically, this problem has been referred to as retransmission timeout (RTO) estimation. Earlier studies show that existing RTO estimators suffer from either long loss detection times or a large number of spurious timeouts. The goal of this study is to address these problems by developing an RTO estimation method specifically tailored for low-delay video applications. In the media-unaware mode, this method exploits the temporal dependence in packet delay to optimally manage the tradeoff between the amount of overwaiting and redundant retransmission rate. As opposed to existing methods, our approach is completely adaptive to the source video characteristics and time-varying network conditions, and does not use any preset parameters. In the media-aware mode, on the other hand, the timeout estimates are jointly optimized based on the importance and urgency of the video packets such that the rendering quality is maximized under the given rate constraints. With a comprehensive set of simulation and experimental results, we show that both the media-unaware and media-aware RTO estimators detect lost packets faster and more accurately than their rivals. Furthermore, our results also substantiate the fact that the media-aware RTO estimator outperforms all other RTO estimators in terms of video quality
Application of the Finite-Element Method to the Inverse Heat Conduction Problem

The surface heat flux at one boundary of a one-dimensional system is computed by using a transient finite-element analysis, given the initial temperature history at on interior node. A technique based on a difference of squares of temperatures is used to determine incremental changes in the surface heat flux. Specifically, two cases are treated. The first case involves an imposed step change in the surface heat flux, and the second involves an imposed surface heat flux that oscillates periodically in the form of a square wave. Comparison of the predicted heat flux with the imposed heat flux provides an evaluation of the inverse technique.
A unified approach to resonances and partons: a survey of the problems and accomplishments

Abstract A brief survey of the recently proposed unified approach to resonances and partons is presented. A new result is the formula for the mean value of the mass of the parton, m = (1 − ad)M n , where a is the average distance between the adjacent hadronic levels, d the radius of the nucleon, and Mn its mass. We also discuss the spacelike states in more detail and give a possible parton model interpretation of this less familiar physical phenomenon.
Comparison of Responses to Edwards Personal Preference Schedule by Chinese and American College Students

A Chinese version of the Edwards Personal Preference Schedule was administered to 249 Chinese college students, 103 men and 146 women. Their scores were compared with those of American peers as reported in a recent study. As compared with American men, Chinese men were significantly higher on Deference, Order, Dominance, Abasement, and Endurance and significantly lower on Exhibition, Intraception, Change, Heterosexuality, and Aggression. The same pattern of cross-cultural differences was found among women. As compared with Chinese women, Chinese men were significantly higher on Dominance, Heterosexuality, Exhibition, and Autonomy and significantly lower on Order, Succorance, Nurturance, and Change. These gender differences were generally consistent with those found among American college students.
Mode I fracture toughness prediction for multiwalled-carbon-nanotube reinforced ceramics

Abstract Eshelby–Mori–Tanaka models with a continuum damage mechanics approach are developed to predict the elastic damage and fracture toughness of multiwalled-carbon-nanotube (MWCNT) reinforced ceramics as a function of MWCNT fraction. This damage model is introduced in a modified boundary layer modeling approach to predict damage accumulation leading to crack propagation from a pre-existing crack tip in a process window where damage and fracture are captured under plane-strain Mode I loading. The model is validated against experimental fracture toughness data for a MWCNT 3-mol% yttria-stabilized zirconia composite and successfully predicts the observed saturation in fracture toughness at about 25% volume fraction MWCNTs.
Development and analysis of a high fidelity linearized J₂ model for satellite formation flying

With the recent flurry of research on satellite formation flying, a need has become apparent for a set of linearized equations of relative motion that capture the effect of the J2 geopotential disturbance force. Typically, Hill's linearized equations of relative motion have been used for this analysis, but they fail to capture the effect of the J2 disturbance force on a satellite cluster. In this paper, a new set of constant coefficient, linearized differential equations of motion is derived. These equations are similar in form to Hill's equations, but they capture the effects of the J2 disturbance force. A numerical simulator is employed to check the fidelity of the equations. It is shown that with the appropriate initial conditions, the new lin earized equations of motion have periodic errors (on the order of centimeters) that do not grow in time. The new linearized equations of motion also allow for insight into the effects of the J2 disturbance on a satellite cluster. This includes 'tumbling', the period of the relative orbit, and satellite separation due to differential J2 effects. Overall, a new high fidelity set of linearized equations are produced that are well suited to model satellite relative motion in the presence of the J2 disturbance force.
Breaking the Box: Simulated Protein Computing

Computers since the 1940s have shared the same basic architecture described by Turing and von Neumann, in which one central processor has access to one contiguous block of main memory. This architecture is challenged by modern applications that require greater parallelism, distribution, coordination, and complexity. Here we show that a model of protein interactions can serve as a new architecture, performing useful calculations in a way that provides for much greater scalability, flexibility, adaptation, and power than does the traditional von Neumann architecture. We found that even this simple simulation of protein interactions is universal, being able to replicate the calculation performed on a digital computer, yet without relying upon a central processor or main memory. We anticipate that the convergence of information- and life-sciences is poised to deliver a platform that invigorates computing as it provides insight into the complexity of living systems.
Distinct Components of Retrograde CaV1.1-RyR1 Coupling Revealed by a Lethal Mutation in RyR1

The molecular basis for excitation-contraction coupling in skeletal muscle is generally thought to involve conformational coupling between the L-type voltage-gated Ca(2+) channel (CaV1.1) and the type 1 ryanodine receptor (RyR1). This coupling is bidirectional; in addition to the orthograde signal from CaV1.1 to RyR1 that triggers Ca(2+) release from the sarcoplasmic reticulum, retrograde signaling from RyR1 to CaV1.1 results in increased amplitude and slowed activation kinetics of macroscopic L-type Ca(2+) current. Orthograde coupling was previously shown to be ablated by a glycine for glutamate substitution at RyR1 position 4242. In this study, we investigated whether the RyR1-E4242G mutation affects retrograde coupling. L-type current in myotubes homozygous for RyR1-E4242G was substantially reduced in amplitude (∼80%) relative to that observed in myotubes from normal control (wild-type and/or heterozygous) myotubes. Analysis of intramembrane gating charge movements and ionic tail current amplitudes indicated that the reduction in current amplitude during step depolarizations was a consequence of both decreased CaV1.1 membrane expression (∼50%) and reduced channel Po (∼55%). In contrast, activation kinetics of the L-type current in RyR1-E4242G myotubes resembled those of normal myotubes, unlike dyspedic (RyR1 null) myotubes in which the L-type currents have markedly accelerated activation kinetics. Exogenous expression of wild-type RyR1 partially restored L-type current density. From these observations, we conclude that mutating residue E4242 affects RyR1 structures critical for retrograde communication with CaV1.1. Moreover, we propose that retrograde coupling has two distinct and separable components that are dependent on different structural elements of RyR1.
Lifecycle Process Model for Municipal Solid Waste Collection

AbstractA process model was developed using a lifecycle approach to estimate the cost and energy use associated with municipal solid waste collection, which is the most fuel-intensive and often the most costly aspect of solid waste management. The model divides collection service areas into single-family residential, multi-family residential, and commercial sectors with sector-specific, user-defined characteristics, including population, waste generation, and waste composition. Waste is collected by a set of processes (e.g., residual waste, recyclables collection) defined by costs, collection activity parameters, and energy use. The model overpredicted fuel use by ~25% compared with data obtained from actual single-family residential collection routes and their average fuel efficiencies, but was within 10% when modal fuel efficiencies (e.g., driving, idling) were considered. Adding recyclables or yard waste collection to a mixed waste collection program increased fuel consumption by approximately 75% per ...
EUS-guided sutured gastropexy for transgastric ERCP (ESTER) in patients with Roux-en-Y gastric bypass: a novel, single-session, minimally invasive approach

Background and study aims: Endoscopic retrograde cholangiopancreatography (ERCP) in patients with Roux-en-Y gastric bypass (RYGB) is a challenging procedure. Available techniques are hampered by limited success, need for a separate delayed session for ERCP, potential complications, and/or invasiveness. This paper reports on a novel technique that involves endoscopic ultrasound (EUS)-guided access into the remnant stomach and sutured gastropexy for transgastric ERCP in a single combined session. Patients and methods: A total of 10 patients with RYGB underwent transgastric ERCP using the novel technique. EUS was used to puncture the excluded stomach through the gastric pouch or jejunum, the stomach was insufflated, and a direct percutaneous gastrostomy puncture followed by sutured gastropexy was performed. ERCP was performed by passing a duodenoscope through the gastrostomy. Results: Technical success of EUS-assisted sutured gastropexy was achieved in nine patients (90 %), with immediate, same-session ERCP in all nine. There were no adverse events. Conclusions: EUS-assisted, fluoroscopically guided sutured gastropexy is a safe and effective method to obtain access into the excluded gastric remnant for same-session transgastric ERCP in patients with Roux-en-Y gastric bypass anatomy.
Making more sense of the order: A review of Canoco for Windows 4.5, PC-ORD version 4 and SYN-TAX 2000

Personal computers of ever-increasing speed have motivated programmers of multivariate software to adapt their programs to be run in Microsoft Windows and Macintosh platforms. Updated versions of these multivariate programs appear more and more frequently and are marketed inten- sively. In this review we provide a comparative analysis of the most recent versions of three analytical software packages - Canoco for Windows 4.5, PC-ORD version 4 and SYN-TAX 2000. The three packages share two characteristics. First, the most recent versions are now compatible with the most recent Windows platforms and should therefore be accessible for use by virtually all vegetation scientists. Second, they have capa- bilities for numerous multivariate techniques, although each package has some unique techniques. Thus, any one of the packages will have much to offer the user.
Continuous Exposure to Sublethal Doses of Synergized Pyrethrins: Effects on Resistance and Repellency in Tribolium confusum (Coleoptera: Tenebrionidae)

Adults of Tribolium confusum Jacquelin du Val from cultures reared on media treated with sublethal doses of synergized pyrethrins were tested at periodic intervals for (1) resistance to the toxic effects of the pesticide, (2) repellency or attractancy of treated paper, and (3) preference for treated or untreated media. After being reared for ca. 4 years on media treated with 50:500 ppm pyrethrins: piperonyl butoxide, the insects developed resistance of 9.1-fold at the LD95. Insects taken from the 50:500 medium after 1.25 years (six filial generations) and reared continuously on media treated with 100:1,000 ppm synergized pyrethrins for 2.67 years developed resistance of 27.7-fold at the LD95. However, these insects were still significantly repelled by concentrations of 5:50 µg/cm2 on kraft paper and 50:500 ppm in treated rearing media although their response was somewhat diminished. The resistant insects were slower to leave a treated area than were the untreated controls.
A Systems Approach to the Design of Information Systems

Systems design consists of a tremendously complex series of choices in which no decision point is completely independent of other decisions which have already been made or have yet to be made. A systems approach to the design of document-handling information systems would require a detailed examination of the choices to be made in the design process and the ramifications of possible choices in terms of the capabilities, performance, cost, and other characteristics of the system. The authors advocate a systematic procedure involving six steps: 1) identification of fixed parameters, 2) identification of variable parameters, 3) identification of available options for each variable parameter, 4) identification of factors affecting a choice among available options, 5) identification of factors affected by a choice among available options, and 6) logical analysis of the picture thus presented to determine the optimum sequence in which decisions should be made during the design process and the nature of the deci...
The effect of chemotherapy-induced anemia on dose reduction and dose delay

Purpose To evaluate moderate (grade 2, hemoglobin <10 g/dl) and severe (grade 3+, hemoglobin <8 g/dl) anemia as potential risk factors for DDR in the first line course of chemotherapy. While chemotherapy-induced neutropenia has been shown to be associated with dose delay/reduction (DDR) in several studies, the effect of anemia is less well studied.
Effects of Aerated Irrigation on Leaf Senescence at Late Growth Stage and Grain Yield of Rice

With the japonica inbred cultivar Xiushui 09, indica hybrid combinations Guodao 6 and Liangyoupeijiu as materials, field experiments were conducted in 2007 and 2008 to study the effects of aerated irrigation on leaf senescence at late growth stage and grain yield of rice. The dissolved oxygen concentration of aerated water evidently increased and decreased at a slow rate. The soil oxidation-reduction potential under aerated irrigation treatment was significantly higher than that of the CK, contributing to significant increases in effective panicles, seed setting rate and grain yield. In addition, the aerated irrigation improved root function, increased superoxide dismutase activity and decreased malondialdehyde content in flag leaves at post-flowering, which delayed leaf senescence process, prolonged leaf functional activity and led to enhanced grain filling.
Pediatrics in the community hospital.

The subject of the community hospital’s pediatric service—its mission, organization, and staff—is ripe for critical study and innovative implementation. This article examines the role of the community hospital in caring for children: what it is and what it could be. The authors offer specific suggestions about how the hospital should define its role and discuss how that role might be carried out.
Leptospermum Honey for Wound Care in an Extremely Premature Infant.

Background/introduction to case Neonatal wound care is challenging due to the fragility and vulnerable skin structure. Neonates are often left susceptible to the forces of their environment, leaving them open to infection when skin injury occurs. Leptospermum honey has been used successfully in adult patients, with evidence lacking in the neonatal population. This case demonstrates the management of a difficult-to-heal wound in a 23-week gestation infant. Purpose Selecting the proper treatment and products for wound healing is challenging, with little evidence-based research available for the treatment of neonatal wounds. Leptospermum honey and other adult-driven dressings have been used for neonatal wound care as well as other adult-driven dressings. This case demonstrates the benefits of Leptospermum honey as an option for neonatal wounds. Case findings/results This case presents the treatment and healing of an extensive wound of a 23-week gestation neonate using a hydrogel product initially and then transitioning to a Leptospermum honey dressing due to suboptimal healing. Results of this treatment included quick healing time, little to no scarring, and no loss of movement or function to the affected extremities. Implications for practice The incorporation of Leptospermum honey for wound care has the potential to promote faster wound healing, with less scarring in the neonatal population. Implications for research Adult wound care principles have been applied in the face of a weak evidence base relating to neonatal-specific cases. There is a need for continued research related to moist wound healing in the neonatal population, with resulting product and practice recommendations.
Trauma-Informed Care Is the Best Clinical Practice in Rehabilitation Nursing.

Purpose This clinical article explores how trauma-informed care (TIC) can be used by rehabilitation nurses with patients who have experienced pervasive adverse childhood experiences (ACEs). Method (Intervention strategies) This clinical article gives suggestions for using the five guiding principles of TIC: safety, trustworthiness, choice, collaboration, and empowerment, as the best clinical practice. Conclusion Implementing TIC promotes successful rehabilitation, improves patient outcomes and reduces costs. For every $1 spent on TIC, $5 is saved in lifetime costs. Clinical Relevance ACEs cause physiological changes in the brain, leading to antisocial and risky behaviors, which may result in head injuries, spinal cord injuries, amputations, and multiple traumas with subsequent rehabilitation admissions, as well as obesity, and chronic illnesses. TIC is a cultural shift: we as providers must ask ourselves “What happened to this person?” instead of “What is wrong with this person?” Nurses are beginning to develop our literature and practice of TIC.
Integration of heterogeneous and biochemical catalysis for production of fuels and chemicals from biomass

The past decade has seen significant government and private investment in fundamental research and process development for the production of biofuels and chemicals from lignocellulosic biomass-derived sugars. This investment has helped create new metabolic engineering and synthetic biology approaches, novel homogeneous and heterogeneous catalysts, and chemical and biological routes that convert sugars, lignin, and waste products such as glycerol into hydrocarbon fuels and valuable chemicals. With the exception of ethanol, economical biofuels processes have yet to be realized. A potentially viable way forward is the integration of biological and chemical catalysis into processes that exploit the inherent advantages of each technology while circumventing their disadvantages. Microbial fermentation excels at converting sugars from low-cost raw materials streams into simple alcohols, acids, and other reactive intermediates that can be condensed into highly reduced, long and branched chain hydrocarbons and other industrially useful compounds. Chemical catalysis most often requires clean feed streams to avoid catalyst deactivation, but the chemical and petroleum industries have developed large scale processes for C-C coupling, hydrogenation, and deoxygenation that are driven by low grade heat and low-cost feeds such as hydrogen derived from natural gas. In this context, we suggest that there is a reasonably clear route to the high yield synthesis of biofuels from biomass- or otherwise derived-fermentable sugars: the microbial production of reactive intermediates that can be extracted or separated into clean feed stream for upgrading by chemical catalysis. When coupled with new metabolic engineering strategies that maximize carbon and energy yields during fermentation, biomass-to-fuels processes may yet be realized.
Primary care physicians are under-testing for celiac disease in patients with iron deficiency anemia: Results of a national survey.

Background Iron deficiency anemia (IDA) is a common extra-intestinal manifestation of celiac disease (CD). Little is known about the frequency with which primary care physicians (PCPs) test for CD in patients with IDA. We aimed to describe how PCPs approach testing for CD in asymptomatic patients with IDA. Methods We electronically distributed a survey to PCPs who are members of the American College of Physicians. Respondents were asked whether they would test for CD (serologic testing, refer for esophagogastroduodenoscopy [EGD], or refer to GI) in hypothetical patients with new IDA, including: (1) a young Caucasian man, (2) a premenopausal Caucasian woman, (3) an elderly Caucasian man, and (4) a young African American man. These scenarios were chosen to assess for differences in testing for CD based on age, gender, and race. Multivariable logistic regression was used to identify independent predictors of testing. Results Testing for CD varied significantly according to patient characteristics, with young Caucasian men being the most frequently tested (61% of respondents reporting they would perform serologic testing in this subgroup (p<0.001)). Contrary to guideline recommendations, 80% of respondents reported they would definitely or probably start a patient with positive serologies for CD on a gluten free diet prior to confirmatory upper endoscopy. Conclusions PCPs are under-testing for CD in patients with IDA, regardless of age, gender, race, or post-menopausal status. The majority of PCPs surveyed reported they do not strictly adhere to established guidelines regarding a confirmatory duodenal biopsy in a patient with positive serology for CD.
Completion Gastrectomy with Esophagojejunostomy for Management of Complications of Benign Foregut Surgery

Abstract Background: With the worldwide epidemic of obesity, an increasing number of bariatric operations and antireflux fundoplications are being performed. Despite low morbidity of the primary fo...
Low-loss bianisotropic metamaterials for time reversal

We discuss the design of two complimentary media for analog detection of sources placed at subwavelength separation using time reversal of observed signals. We have used two metasurfaces composed of bianisotropic structures to code and decode the evanescent fields of the sources to propagating waves. In order to reduce losses and create a perfect focus, resonances are avoided to achieve negative index. We have studied various shapes such as, split ring resonators to determine the least lossy structure for time reversal. We have used simulations to study the behavior of permittivity and permeability values of these structures at various frequencies. Shape parameters such as size of the gap and thickness is being optimized to achieve refractive index of ± 1 at the same frequency and minimize losses in the metasurfaces.
Vowel Shifts and Mergers

Vowel shifting and vowel mergers have been central to quantitative sociolinguistics since its inception. They have furnished variables for a variety of sociolinguistic studies around the world. The causes of vowel shifting, vowel mergers, and vowel splits have attracted considerable attention. Economy of effort, vowel dispersion theory, and, more recently, Labov's principles of vowel shifting have been proposed to account for them. Mergers involve special problems, such as how to determine whether a merger has really taken place and conditions under which a merger can be reversed.
Justice Rehnquist and 'the Freedom of Speech, or of the Press'

After 33 years on the Supreme Court, what can we say about Justice Rehnquist's record on the freedom of speech, and of the press? This paper examines his voting pattern and finds not only that he was by far the justice least likely to support such claims, but also that his approach to these issues was largely unprincipled, result-oriented, and incompatible with any plausible theory of the First Amendment.
Pharmacology of Hypocretin/Orexin Peptides and Small Molecules

Despite their relatively recent discovery in 1998, the hypocretins (also known as orexins) and their receptors are already the focus of several investigations as sites for therapeutic intervention in a number of endocrinological and neurological disorders. The rapidity with which the hypocretin system has been adopted as a high-interest target is mainly the result of an accumulation of compelling evidence from in vivo studies showing that the hypocretins regulate a number of aspects of physiology and behavior, especially those involved in sleep, arousal, and energy homeostasis. High-throughput screening efforts by a number of pharmaceutical companies have now identified novel small molecules that interact potently and specifically with the hypocretin receptors. Despite these considerable efforts, very little is known regarding the structures of the receptors, their endogenous ligands, the molecular basis of their interactions, or the signaling pathways they use. For example, no attempt has been made through receptor mutagenesis, or by any other means, to define the key interactions that occur between the receptors and the endogenous peptide ligands. Although such studies are likely to be ongoing within pharmaceutical companies with active hypocretin receptor drug discovery programs, the information available to the general scientific community remains very limited. This chapter reviews what is currently known about the molecular pharmacology of this system, focusing on the structures and activities of the peptides and some of the small molecules for which published biological data exist.
Time-Series Analysis of Air Pollution and Health Accounting for Covariate-Dependent Overdispersion

Time-series studies are routinely used to estimate associations between adverse health outcomes and short-term exposures to ambient air pollutants. Use of the Poisson log-linear model with the assumption of constant overdispersion is the most common approach, particularly when estimating associations between daily air pollution concentrations and aggregated counts of adverse health events throughout a geographical region. We examined how the assumption of constant overdispersion plays a role in estimation of air pollution effects by comparing estimates derived from the standard approach with those estimated from covariate-dependent Bayesian generalized Poisson and negative binomial models that accounted for potential time-varying overdispersion. Through simulation studies, we found that while there was negligible bias in effect estimates, the standard quasi-Poisson approach can result in a larger standard error when the constant overdispersion assumption is violated. This was also observed in a time-series study of daily emergency department visits for respiratory diseases and ozone concentration in Atlanta, Georgia (1999-2009). Allowing for covariate-dependent overdispersion resulted in a reduction in the ozone effect standard error, while the ozone-associated relative risk remained robust to different model specifications. Our findings suggest that improved characterization of overdispersion in time-series modeling can result in more precise health effect estimates in studies of short-term environmental exposures.
Parent report of provider HPV vaccine communication strategies used during a randomized, controlled trial of a provider communication intervention.

Abstract Objective To assess secondary, parent-reported outcomes from a randomized controlled trial (RCT) of a provider communication intervention aimed at improving adolescent HPV vaccination. Methods A paper survey was provided to a random sample of 777 parents of adolescents from 8 control and 8 intervention clinics participating in the larger trial. Chi-square or Fisher’s exact tests assessed associations between study arm and providers’ HPV vaccine communication strategies, parents’ vaccination attitudes and parent’s HPV vaccine acceptance. Exploratory analyses assessed the association between receipt of ‘very strong’ or presumptive HPV vaccine recommendation (regardless of study arm) and parent’s perceptions about their providers’ vaccine communication, and parents’ attitudes and acceptance of the HPV vaccine. Results The response rate was 47%. There were no differences between study arms in parents’ report of how their provider communicated about the HPV vaccine, parent vaccination attitudes, or uptake of the HPV vaccine. Receipt of a ‘very strong’ recommendation was associated with greater perceived urgency for getting vaccinated, greater trust in the information received from the provider, decreased vaccine hesitancy, and increased vaccine receipt. Receipt of a presumptive recommendation was associated with a lower likelihood of having concerns about the vaccine’s safety, lower vaccine hesitancy, and an increased likelihood of vaccination. Neither recommendation strategy appeared to negatively impact parents’ visit experience or trust in the information being provided. Similar results were found in sub-analyses of vaccine hesitant parents. Conclusions Providing very strong, presumptive HPV vaccine recommendations is associated with improved parent vaccination attitudes and acceptance, and does not seem to have significant negative impacts, even among parents who are vaccine hesitant. Response bias in our sample could explain why there were no reported differences between study arms in parents’ reports of how their adolescent’s providers communicated about the HPV vaccine.
Longitudinal Cognitive and Behavioral Presentation of Adult Female with Kabuki Syndrome

BACKGROUND Kabuki syndrome (KS) is a rare disease with an estimated prevalence of approximately 1: 32 000. While the clinical presentation of KS is heterogeneous, manifestations may include: characteristic facial features, postnatal growth retardation, and skeletal abnormalities. With regards to the cognitive profile, most individuals with KS have an Intellectual Disability, but the magnitude of the impairment ranges from mild to severe, and verbal abilities are generally stronger than nonverbal abilities (i.e., visual spatial and visual perception abilities). Given the low incidence of KS, there is limited literature illustrating the longitudinal development of individuals with the condition. This report presents the cognitive and behavioral trajectory of an individual with KS. CASE REPORT The patient in this case report was a 27-year-old female with KS. Her cognitive profile had remained in the average range over time, but consistent with the limited KS literature, her verbal abilities were significantly higher than her nonverbal abilities. Specifically, our patient demonstrated significant deficits in visual motor and visual perceptual skills. With regards to her core language skills, her expressive skills were average, yet her receptive skills were below average. Throughout the majority of her schooling, her academic achievement skills were mildly delayed. Notably, her performance on cognitive and academic assessments remained stable over time. During young adulthood, she developed significant internalizing symptoms, particularly depressive symptoms. CONCLUSIONS This is the first case report to illustrate the presentation of an individual with KS from toddlerhood through young adulthood. The patient's clinical presentation across time was relatively consistent with the KS literature to date; notable patterns of language, motor, cognitive and behavioral deficits illustrate the considerable heterogeneity that exists within the syndrome. This case report, particularly, illustrates the persistence of the cognitive profile over time and also the co-occurring psychiatric symptoms that might emerge.
Label-free Bio-aerosol Sensing Using On-Chip Holographic Microscopy and Deep Learning

We present automated and label-free bio-aerosol sensing using a portable and cost-effective device, enabled by on-chip digital holographic microscopy and deep-learning.
Secondary Malignancies of the Pancreas

Secondary malignancies of the pancreas represent 4.5% to 11% of all pancreatic malignancies. They may result from hematogenous spread from distant primary tumors or through direct invasion by tumors from adjacent structures, such as the stomach, duodenum, and biliary tract. Blood-borne metastases are more frequent than involvement by direct invasion and the most common sites of origin include the kidney, breast, and lung. It should be noted that these lesions are most commonly sampled when either the primary tumor is unknown or when the primary was treated years ago and presumed to be cured. As such, it should not be surprising that malignancies such as renal cell carcinoma and melanoma represent a significant portion of the lesions sampled.
Using an Adventure Therapy Activity to Assess the Adlerian Lifestyle

The lifestyle is a central concept in Adlerian theory necessary for understanding a client and the purpose of behavior. Although there are a variety of methods counselors can employ to explore the ...
Conflict, Cooperation, and the Global Auto Factory

Since 1973, the American automobile industry has experienced a shift toward more cooperative labor relations. Many observers saw the 1984 contract between General Motors (GM) and the United Auto Workers as a pathbreaking agreement marking the beginning of a new era of cooperation. Historically, the legacy of labor relations in the auto industry has been one of conflict, from the time of bloody violence over the right to unionize in the late 1930s to the protracted standoff between workers and management over issues of workplace control at Lords town in 1972. In contrast, since the initiation of a Quality of Worklife program at GM in 1973, there have been an increasing number of cooperative arrangements to address both new issues and reemerging issues. The central provision of the 1984 GM-UAW pact—a “job bank” providing for placement of workers displaced by new technology and other causes—is one of the most noteworthy examples. However, labor relations in the auto industry are still characterized by considerable conflict, as the 1984 pact was reached only after corporate threats and a strike by the UAW. The goal of this essay is to explain the shift toward more cooperative labor relations in the auto industry, with a special focus on the role of conflict itself. The nature of this cooperation will also be examined in terms of the relative power of labor and management to pursue contradictory interests.
Influencer advertising on social media: The multiple inference model on influencer-product congruence and sponsorship disclosure

Abstract This study investigates the effects of influencer advertising attributes on consumer responses via multiple motive inference processing. Influencer-product congruence and sponsorship disclosure are manipulated as independent variables. In so doing, this study examines whether social media users infer two types of motives (Affective vs. Calculative) of the influencer derived from perceived congruence (High vs. Low) and sponsorship disclosure (Presence vs. Absence). Results suggest that influencer-product congruence can be used to enhance product attitude and reduce advertising recognition by generating a higher affective motive inference. Sponsorship disclosure can also affect product attitude in a serial mediation of calculative motive inference and advertising recognition. The multiple motive inference model explained the dual processing of influencer advertising by attributing to the prior persuasion knowledge and situational characteristics simultaneously. The findings discussed theoretical and managerial implications on native advertising on social media.
Chapter 169 – Mites

Publisher Summary This chapter discusses the mites that comprise the Acari, which are the largest group within the arthropod class Arachnida, with over 48,000 described species. This number is misleading because it is estimated that only between 5% and 10% of all mite species have been formally described. In contrast with other arachnid groups such as spiders and scorpions, mites are distinctive in both their small size (adult body length ranging from 0.1 to 30 mm) and their ecological diversity. Some mites are predators, like almost all other arachnids, but mites may also feed on plants, fungi, or microorganisms or as parasites on or in the bodies of other animals. Mites are among the oldest known groups of arthropods, with a fossil record beginning in the Devonian period. Knowledge of mites is important as it explicitly influences humans. Many species are serious pests of agricultural crops, either through direct damage or indirectly as vectors of plant pathogens. Other species are parasitic on domestic animals and cause losses in meat, egg, and fiber production. Others, such as the human scabies mite, are direct agents of human disease or, as in the case of chiggers and ticks, vectors of pathogens. Other mites may affect humans by infesting stored food products. Many species of Astigmata are known as stored-product mites because they have moved from their ancestral rodent nest habitats into human food stores. Such mites may also cause damage in animal feed by causing allergic reactions in livestock and are also known to cause skin irritation in humans handling infested materials.
Future Work: Search for Compressed Wino-Bino Production in the Three Lepton Final State

This search benefits from the techniques developed in both the wino-bino search, in Chap. 7 and the compressed searches in Chap. 10 because the SUSY particles decay via off-shell bosons just like in the compressed searches but the final state is three leptons and \(E_{\mathrm {T}}^{\mathrm {miss}}\) just as in the wino-bino search. In the summary limit shown in Fig. 11.1, the compressed search can be found along the diagonal where \(m(\tilde{\chi }_2^{0})=m(\tilde{\chi }_1^{0})\). The wino-bino and the RJR searches limits can be found start at \(m(\tilde{\chi }_1^{+},\tilde{\chi }_1^{-})= 200{\mathrm {\ GeV}}\) and \(m(\tilde{\chi }_1^{0})=100{\mathrm {\ GeV}}\).
Canonical Equation K34 for Normalized Spectral Functions of Empirical Covariance Matrix with Asymptotically Independent Blocks

The asymptotic properties of normalized spectral functions of empirical covariance matrices are studied in the case of a nonnormal population. It is shown that the Stieltjes transforms of such functions satisfy the so-called canonical equation. In this chapter, we give only canonical equations. While the proofs of these equations may appear complicated, their main formulas are not extraordinary difficult. The reader, possessing basic understanding of the theory of matrices, can check them without much trouble. This is why, for analogous equations in subsequent chapters, we only indicate the main steps of proofs without giving detailed calculations.
Axillary response rates to neoadjuvant chemotherapy in breast cancer patients with advanced nodal disease.

Purpose Utilization of sentinel lymph node biopsy (SLNB) in breast cancer patients with positive nodes after neoadjuvant chemotherapy (NAC) has increased. We examine axillary response rates after NAC in patients with clinical N2-3 disease to determine whether SLNB should be considered. Methods Breast cancer patients with clinical N2-3 (AJCC 7th Edition) disease who received NAC followed by surgery were selected from our institutional tumor registry (2009-2018). Axillary response rates were assessed. Results Ninety-nine patients with 100 breast cancers were identified: 59 N2 (59.0%) and 41 (41.0%) N3 disease; 82 (82.0%) treated with axillary lymph node dissection (ALND) and 18 (18.0%) SLNB. The majority (99.0%) received multiagent NAC. In patients undergoing ALND, cCR was observed in 20/82 patients (24.4%), pathologic complete response (pCR) in 15 patients (18.3%), and axillary pCR in 17 patients (20.7%). In patients with a cCR, pCR was identified in 60.0% and was most common in HER2+ patients (34.6%). Conclusion In this analysis of patients with clinical N2-3 disease receiving NAC, 79.3% of patients had residual nodal disease at surgery. However, 60.0% of patients with a cCR also had a pCR. This provides the foundation to consider evaluating SLNB and less extensive axillary surgery in this select group.
Approaches to Transitioning Computer Science Classes from Offline to Online

As the COVID-19 pandemic spread throughout the United States in Spring 2020, universities around the country conducted the unprecedented feat of moving essentially their entire curricula online. This abrupt mid-semester shift in modality was the first of its kind at scale, but it will not be the last. Now that our experiences during the pandemic have demonstrated that an online transition is possible, we may see similar transitions proposed during smaller scale crises, especially as an alternative to school closures. We present an experience report focusing on computer science instructors at a large Midwestern university during the Spring 2020 online transition: the challenges they faced, as well as the interventions they implemented. As more data and analysis is generated from the first mass, unwilling modality shift, it is nevertheless important to focus on the visceral reactions and lessons learned from teachers and students in the moment as they responded to an unprecedented situation. We therefore also present our analysis of critical challenges and preliminary pedagogical recommendations for consideration during future rapid transition "involuntarily online" semesters.
Recreational cannabis laws and opioid-related emergency department visit rates.

The opioid epidemic in the United States has accelerated during the COVID-19 pandemic. As of 2021, roughly a third of Americans now live in a state with a recreational cannabis law (RCL). Recent evidence indicates RCLs could be a harm reduction tool to address the opioid epidemic. Individuals may use cannabis to manage pain, as well as to relieve opioid withdrawal symptoms, though it does not directly treat opioid use disorder. It is thus unclear whether RCLs are an effective policy tool to reduce adverse opioid-related health outcomes. In this study, we examine the impact of RCLs on a key opioid-related adverse health outcome: opioid-related emergency department (ED) visit rates. We estimate event study models using nearly comprehensive ED data from 29 states from 2011 to 2017. We find that RCLs reduce opioid-related ED visit rates by roughly 7.6% for two quarters after implementation. These effects are driven by men and adults aged 25-44. These effects dissipate after 6 months. Our estimates indicate RCLs did not increase opioid-related ED visits. We conclude that, while cannabis liberalization may offer some help in curbing the opioid epidemic, it is likely not a panacea.
U.S. Synagogues’ Promotion of Physical Activity to Adults: An Online Media Content Analysis

We completed systematic line-by-line analyses of 1383 U.S. synagogues’ websites’ – publicly accessible webpages, online brochures/newsletters, online calendars – to assess content that mentioned ph...
PMNet: in-network data persistence

To guarantee data persistence, storage workloads (such as key-value stores and databases) typically use a synchronous protocol that places the network and server stack latency on the critical path of request processing. The use of the fast and byte-addressable persistent memory (PM) has helped mitigate the storage overhead of the server stack; yet, networking is still a dominant factor in the end-to-end latency of request processing. Emerging programmable network devices can reduce network latency by moving parts of the applications' compute into the network (e.g., caching results for read requests); however, for update requests, the client still has to stall on the server to commit the updates, persistently. In this work, we introduce in-network data persistence that extends the data-persistence domain from servers to the network, and present PMNet, a programmable data plane (e.g., switch or NIC) with PM for persisting data in the network. PMNet logs incoming update requests and acknowledges clients directly without having them wait on the server to commit the request. In case of a failure, the logged requests act as redo logs for the server to recover. We implement PMNet on an FPGA and evaluate its performance using common PM workloads, including key-value stores and PM-backed applications. Our evaluation shows that PMNet can improve the throughput of update requests by 4.31X on average, and the 99th-percentile tail latency by 3.23X.