cssi/SciSciGPT-SciSciNet huggingface dataset:
Pharmacological responsiveness of dissociated native and cultured eccrine secretory coil cells

Methacholine (MCh)- and isoproterenol (Iso)-stimulated 14CO2 production was compared between freshly dissociated rhesus sweat secretory coil cells (mainly clear cells) and cultured cells (grown on a collagen-coated plastic plate) derived from native cells. 14CO2 production was enhanced by MCh and by Iso in native coil cells (but not in ductal cells) in a pharmacologically specific and dose-dependent manner. 14CO2 production in subcultured coil cells (19-45 days in culture) was only one-third to one-fifth that of native cells. MCh-stimulated 14CO2 production was inhibited by ouabain and furosemide in both native and cultured coil cells. A decrease in 14CO2 production, of about one-half, was already evident in primary cells cultured for less than 1 wk. The decreased pharmacological responsiveness of the cultured coil cells was seen, although the cultured cells showed the typical epithelioid appearance, abundant mitochondria, the occasional presence of intercellular lacunae resembling intercellular canaliculi, and the persistence of immunoreactive keratin. We conclude that 1) a primary culture of sweat gland cells can be initiated from dissociated cells; 2) cultured sweat secretory coil cells qualitatively, but not quantitatively, retain the pharmacological responsiveness and transport activity of the native cells as determined by 14CO2 production; 3) collagenase-dissociated cells represent an excellent in vitro system for the study of glandular function at the cellular level; and 4) the decrease in pharmacological responsiveness is not simply due to trypsin treatment during harvesting of cultured cells, because that of organ-cultured, intact, secretory coils also declines with time of culture.
Regional Nationalism and Soviet Anxieties during the Great Terror in Ukraine: The Case of Mykhailo Bykovets'

Abstract: This study examines Soviet nationalities policies and the elimination of Ukrainian intellectuals during the Great Terror in Ukraine by exploring the individual history of the Ukrainian literary figure Mykhailo Bykovets', one of the founders of the literary association “Pluh” (Plough) and one of the initiators of the Literary Discussion that emerged in the mid-twenties. The research explores the modus operandi of a key Soviet institution, the GPU/NKVD, and its proactive methods of the de-nationalization of Ukrainian society. Bykovets’s criminal case seems to be axiomatic of the Great Terror, exhibiting common patterns of the secret organs’ procedural and investigative tactics. Through an analysis of Bykovets’s archival file, and the themes and questions that were central to the investigation of Bykovets’s “crimes,” the study illuminates the persistent national vector of repression against the representatives of the Ukrainian intelligentsia during the Great Terror. Keywords: The Great Terror, Secret Police, Kharkiv, Ukrainian Intellectuals, Mykhailo Bykovets'
Motion Planning

This is the first installment of a two-part tutorial. The goal of the first part is to give the reader a basic understanding of the technical issues and types of approaches in solving the basic path-planning or obstacle-avoidance problem. The second installment will cover more advanced issues, including feedback, differential constraints, and uncertainty. Note that this is a brief tutorial rather than a comprehensive survey of methods. For the lat ter, consult some of the recent textbooks. Motion planning involves getting a robot to automatically determine how to move while avoiding collisions with obstacles. Its original formulation, called the piano mov er's problem, is imagined as determining how to move a complicated piece of furniture through a cluttered house. Have you ever argued about how to move a sofa up a stairwell? It has been clear for several decades that getting robots to reason geometrically about their environments and synthesize such plans is a fundamental difficulty that recurs all over robotics.
Seismic moment tensors and estimated uncertainties in southern Alaska

We present a moment tensor catalog of 106 earthquakes in southern Alaska, and we perform a conceptually based uncertainty analysis for 21 of them. For each earthquake, we use both body waves and surface waves to do a grid search over double couple moment tensors and source depths in order to find the minimum of the misfit function. Our uncertainty parameter or, rather, our confidence parameter is the average value of the curve 𝒫(V), where 𝒫(V) is the posterior probability as a function of the fractional volume V of moment tensor space surrounding the minimum misfit moment tensor. As a supplemental means for characterizing and visualizing uncertainties, we generate moment tensor samples of the posterior probability. We perform a series of inversion tests to quantify the impact of certain decisions made within moment tensor inversions and to make comparisons with existing catalogs. For example, using an L1 norm in the misfit function provides more reliable solutions than an L2 norm, especially in cases when all available waveforms are used. Using body waves in addition to surface waves, as well as using more stations, leads to the most accurate moment tensor solutions.
PHANTOMM flow tagging measurements in complex 3D flows

Using the PHANTOMM flow tagging technique we obtain quantitative measurements of velocity, as well as visualizations similar to those obtained with standard laser sheet fluorescence techniques, of the flow in a cylinder driven by a rotating end wall. In addition, the axisymmetric Navier-Stokes equations are solved numerically using a vorticity stream function formulation. The computed flow is compared to measurements in order to evaluate and validate the PHANTOMM technique so that one can be confident of measurements in flow regimes where accurate computations are not available. (Author)
Ineffectiveness of Histaminase in Anaphylactic Shock in Guinea Pigs.

ConclusionThe protective action of histaminase on anaphylactic shock of guinea pigs as reported by Karady and Browne could not be confirmed.
Behavioral Responses by Scolytus multistriatus (Coleoptera: Scolytidae) to Host- (Ulmus) and Beetle-Associated Chemotactic Stimuli

Host logs and host logs plus attacking beetles both were attractive to in-flight Scolytus multistriatus (Marsham) in field experiments. Ulmus americana logs per se also were attractive to the beetles in laboratory bioassays. Attraction of beetles increased following initial beetle attacks on logs in the field. Logs with attacking female S. multistriatus , screened to prevent further attack, gave a significantly greater attraction than any other host or host-beetle combination tested.
Hierarchical modeling and scalable algorithms for in-situ characterization of 3D IC packages

The objective of this work is to investigate high-resolution and high-performance computational methods for the first-principles analysis of in-situ product-level integrated circuit (IC) packages. The novelties and key technical approaches of the proposed work include: (i) a scalable geometry-based domain decomposition (DD) method to conquer the geometric complexity of physical domain, which leads to quasi-optimal convergence that is provably scalable for multi-scale objects. Moreover, it results in parallel and scalable computational algorithms to reduce the time complexity via high performance computing facilities; (ii) a hierarchical multi-scale simulator for high-definition IC package systems, in which the technical ingredients include a skeleton-based multi-region multi-solver method and a variational macro-micro analysis for multi-scale modeling. The capability and benefits of the algorithms are explored and illustrated through several real-world 3D IC package applications.
A Cooperative Particle Swarm Optimization Based State Estimation of Unbalanced Three-Phase Distribution Network

In allusion to the optimization of state estimation on unbalanced three-phase distribution network, a particle swarm optimization based cooperative particle swarm optimization(Co-PSO) algorithm is proposed, that is, during the global optimization of main swarm the state variables are divided into multi independent sub-spaces and each sub-space is solved by one sub-swarm; the sub-swarms are optimized based on the global optimization result of main swarm, and the optimization results of sub-swarms are continually led into main swarm and both two kinds of swarms evolve cooperatively and promote mutually. Experimental results of IEEE 13-bus system, IEEE 37-bus system and IEEE 123-bus system show that using the proposed optimization method the uncertain load and the output of distributed generations can be estimated effectively. Through comparing the proposed method with basic particle swarm optimization and various improved particle swarm optimizations as well as with genetic algorithm, the effectiveness and applicability of the proposed Co-PSO algorithm are validated.
Influence of Parents' Cooperation on the Rehabilitation Effect of Deaf Children

Objective To study the influence of parents’support on the effect of auditory and speech rehabilitation training in deaf children.Methods We designed a questionnaire including information about the parents:their quality,rational facing reality,active participation,cooperation with training guide; or escape,self-blame and dotingness,child abuse,and depending on the rehabilitation center. We divided the children into two groups according to the questionnaire;30 children with parents cooperating actively and rationally were divided into the experimental group,and another 30 children with parents escaping and excluding were divided into the control group. Results High quality,active participation and active cooperation with the rehabilitation training of the parents had positive effect on their deaf children’s rehabilitation effect. In this condition,the courses of training was shorter,auditory compensation and speech definition of training were shorter auditory compensation and speech definition of the children were much better;Escape,abandon,self-blame,dotingness and seeking for treatment blindly were negative behaviors of parents with deaf children,and these behaviors restricted rehabilitation effect. Conclusion The deaf children,their parents and teachers are three important factors in the deaf rehabilitation. Parents are the first teacher in a child’s life,active cooperation of them has positive effect on the deaf rehabilitaion. With their parents’help,the deaf children could integrate into the society and be admitted by ordinary kindergartens and schools as possible. On the contrary,parents with negative attitude will restrict rehabilitation training,and abandoning treatment will result in permanent disability of their deaf children which brings about social and family burden.
Interrelationships between glutamine and citrulline metabolism.

Purpose of reviewThis article analyzes the contribution of glutamine to the synthesis of citrulline and reviews the evidence that glutamine supplementation increases citrulline production.Recent findingsGlutamine supplementation has been proposed in the treatment of critically ill patients; however,
Songun Politics and the Political Weakness of the Military in North Korea: An Institutional Account

At the heart of the unexpected regime stability in post–Kim Il-sung Pyongyang is the expanded role of the Korean People’s Army (KPA) as the protector of the regime and the leader, under the slogan of military-first (songun) politics. There is, however, a wide gap between the KPA’s role and its limited political significance. This article examines how Pyongyang’s political systems were designed to enable the leader to firmly control the military and security organizations by focusing on three of the most important institutions related to control over the KPA: the General Political Department, the Central Military Commission, and the National Defense Commission.
Electoral Reform and National Security in Japan: From Pork to Foreign Policy

Japan is the third-largest economy in the world and a key ally of the United States. Yet the determinants of Japanese security policy are not well understood. The question of why Japan never sought the independent military capabilities that would be commensurate with its economic power has puzzled scholars of international relations for decades. Applying new tools for the quantitative analysis of text to a new collection of 7,497 Japanese-language election manifestos used in elections between 1986 and 2009, this book argues that the electoral strategies politicians in the ruling party were forced to adopt under Japan's old electoral system made it extraordinarily difficult for them to focus on security issues and to change security policy. It was only when their electoral strategies shifted after electoral reform in 1994 that these same politicians became able to pay attention and change security policy.
Surgery for Peripheral Nerve Trauma

It has been estimated that primary or concomitant peripheral nerve injuries comprise 2-3% of Level I trauma center admissions in the USA annually, with the incidence rising to about 5% with the inclusion of brachial/lumbar plexus and other nerve root injuries. Peripheral nerve injuries may be sustained by a variety of mechanisms, the most common of which are stretch injuries and lacerations. Upper extremity nerve injuries occur more frequently than lower extremity injuries. The severity of peripheral nerve injury is classified based on the extent of disruption of the neural and connective tissue elements, most commonly via the Seddon or Sunderland classification systems. Aside from the invaluable history and physical exam, electrodiagnostic studies such as nerve conduction velocities and electromyography are important in the evaluation of peripheral nerve injuries and to help guide operative and non-operative treatment decisions. Following the initial assessment and determination of the type and extent of injury, either observation or surgical repair should be instituted. Operative lesions should be treated early, and lesions deemed non-operative which do not exhibit the expected progression warrant surgical exploration. The initial step in any type of repair is to clean the proximal and distal nerve stumps to expose healthy fascicles. Extra care must be taken to ensure the repair is not under tension and can withstand a physiologic range of motion. Surgical techniques for repair include end-to-end suturing of proximal and distal stumps, synthetic nerve grafts, interposition grafting with autologous donor nerves, and nerve transfer using a proximally intact adjacent nerve as a proxy for the proximal stump.
Detection of Heated Bacterial Spores with Fluid Thioglycollate and Soybean Casein Digest Broths Containing Variable Concentrations of Solids.

Spore suspensions of Bacillus stearothermophilus (ATCC 7953, 10149, 12980), Bacillus subtilis (ATCC 6633), Bacillus subtilis var. niger (ATCC 9372), Bacillus pumilus (ATCC 27142, and a wild strain) and Bacillus cereus (ATCC 11778) were heated (20 min at 121°C for thermophiles, and 2.5-20 min at 100°C, 105°C, or 107°C for mesophiles) in 1 ml sealed ampoules. Surviving spores were recovered by a 5-tube most probable number (MPN) procedure with soybean casein digest (SCD) or fluid thioglycollate (FTH) broths containing variable concentrations of solids. Numbers of heated thermophilic spores (ATCC 7953) recovered with SCD broths were approximately 1.5 log MPN/ml higher at the 100% broth solids concentration than numbers recovered with FTH broth. Increasing the solids of SCD broth to twice the recommended amount (200%) reduced recovery of heated thermophilic spores compared to regular (100%) strength broth. Recovery of heated thermophilic spores with SCD or FTH broths was higher (P 0.05) influence recovery of heated mesophilic spores compared to SCD broth with regular concentration of solids. Broths with reduced as well as regular concentrations of solids were equally effective in recovering unheated spores. These results should be useful in future modifications of methodology for sterility testing.
Hexavalent Americium Recovery Using Copper(III) Periodate

Separation of americium from the lanthanides is considered one of the most difficult separation steps in closing the nuclear fuel cycle. One approach to this separation could involve oxidizing americium to the hexavalent state to form a linear dioxo cation while the lanthanides remain as trivalent ions. This work considers aqueous soluble Cu3+ periodate as an oxidant under molar nitric acid conditions to separate hexavalent Am with diamyl amylphosphonate (DAAP) in n-dodecane. Initial studies assessed the kinetics of Cu3+ periodate autoreduction in acidic media to aid in development of the solvent extraction system. Following characterization of the Cu3+ periodate oxidant, solvent extraction studies optimized the recovery of Am from varied nitric acid media and in the presence of other fission product, or fission product surrogate, species. Short aqueous/organic contact times encouraged successful recovery of Am (distribution values as high as 2) from nitric acid media in the absence of redox active fissio...
Dosing strategies for switching from oral risperidone to paliperidone palmitate: Effects on clinical outcomes.

Abstract Introduction: There are currently no guidelines for switching patients from oral risperidone to paliperidone palmitate (Invega Sustenna®). Furthermore, the paliperidone long-acting injectable (LAI) package insert does not recommend bridging with oral antipsychotics, which may result in inadequate serum concentrations in patients on ≥4 mg/d risperidone. Methods: This study evaluated the effects of suboptimal dosing and bridging in patients switched from oral risperidone to paliperidone LAI on hospitalization days, emergency department (ED)/mental health urgent care visits, and no-shows/cancellations to mental health appointments. Patients were categorized into optimal or suboptimal dosing based on their loading and maintenance paliperidone doses. Patients on risperidone ≥4 mg/d were categorized as bridged if they received risperidone for ≥7 days after the first paliperidone injection. Results: There were no significant differences in outcomes between optimally and suboptimally dosed patients. Ther...
Decisions around Long-term Ventilation for Children. Perspectives of Directors of Pediatric Home Ventilation Programs.

Rationale: The decision of whether to initiate or forgo long-term ventilation (LTV) for children with life-limiting conditions can be complex and impactful. Providers are responsible for helping families to understand the consequences of their options and guiding them through shared decision-making, but little has been published on how to do this.Objectives: To assess how directors of pediatric home ventilation programs facilitate shared decision-making with families facing decisions of whether to initiate or forgo LTV for their children with life-limiting conditions. In addition, to assess directors’ perspectives on these families’ decisional needs.Methods: Purposeful recruiting of directors/codirectors of pediatric home ventilation programs at children’s hospitals was used. We performed semistructured interviews using an open-ended interview guide developed de novo to assess their approach to informed, shared decision-making around LTV and their perspectives on these decisions. Qualitative data analysis...
Intelligent Selection of Cutting Parameters in Milling Operation

Abstract For mass production of uniform quality demand in modem industry, computer numeric control (CNC) machining is widely used. One of evident phenomena in machining is that tool wear is not avoidable. Hence, the best management of cutting tool in mass product is the minimization of tool wear during sequential machining processes. To provide cutting information in wide cutting range, a systematic selection of cutting parameters is essential for strong foundation in advanced machining industry. When this feature is added in conventional CAD/CAM systems, it is possible that the seamless machining with safe and efficient cutting parameters state in various cutting range.
Titanium plate fixation of flail chest

Abstract Introduction We present short and long term outcomes of titanium rib plating in two pediatric patients with traumatic flail chest. Cases Patient 1 is a 12 year old male ATV driver with left thorax handlebar impalement with a flail segment of ribs 4–8. He was unable to wean from the ventilator by hospital day (HD) 4 and had titanium plating of ribs 4–7. He was extubated on postoperative day (POD) 1 and discharged home on POD 5. He returned to contact sports at 6 months. Patient 2 is a 13 year old male dirt bike rider with fractures of left ribs 8–12, including a 9–10 flail segment. He was unable to wean from the ventilator by HD 3 and had titanium plating of ribs 8–10. He was extubated on POD 2 and discharged on POD 11. After 4 months of therapy, he returned to full activity. Conclusions In these two patients, flail chest resulted in failure to wean from the ventilator. Plating of the flail segment allowed ventilator weaning, improved pain control, and return to normal activity with minimal symptoms. Long-term outcomes show excellent cosmetic and functional results with symmetric chest wall growth (Table 1) Level of evidence IV.
Transcending dementia through the TTAP Method: A New Psychology of Art, Brain and Cognition, by Linda Levine Madori Ph. D., Health Professions Q2 Press Incorporated, 264 pp., $48.31, ISBN-13: 978-1932529722.

Transcending Dementia seeks to offer a more affordable care practice that does not compromise the quality of life and enhance the cognitive ability remaining in older adults with Alzheimer’s dement...
China: Scripts, Non-Chinese

In the 1950s, Chinese linguists began to create scripts for over a dozen of the 55 official ethnic minority groups (shaoshu minzu) that lacked traditional or more recent writing systems. Initially, Cyrillic and roman alphabets were utilized, sometimes in concert with IPA symbols. Ultimately, 13 official scripts using roman letters were adopted, including dialects of Zhuang and Miao. An exception is the new syllabary for a major dialect of Yi in Sichuan, based on traditional logographs. Social and economic pressures in China will be a determining factor in the continued use of both the traditional and new minority scripts.
Minorities as Perpetrators and Victims of Crime

This article examines the involvement of minorities in criminal activities in the United States. It further analyzes the disproportionate number of minorities in jails, prisons, and on death row. To better understand this relationship, both traditional and nontraditional views on race and crime are presented. There is also a discussion of minorities as victims of crime.
A Randomized Single-Blinded Trial of Posttonsillectomy Liposomal Bupivacaine among Adult Patients.

ObjectiveTo determine whether liposomal bupivacaine (Exparel) is safe and effective in the management of posttonsillectomy pain among adult patients.Study DesignA prospective single-blind randomize...
Dietary oxalate and kidney stone formation.

Dietary oxalate is plant-derived and may be a component of vegetables, nuts, fruits, and grains. In normal individuals, approximately half of urinary oxalate is derived from the diet and half from ...
Past Meets Present: Monsoon Wedding Redux

Mira Nair’s Monsoon Wedding provokes questions on the limits and boundaries of hospitality and acceptance. Can the camaraderie in Monsoon Wedding transcend economic class and social markers to promise an optimistic dance that thinks of equality with a difference? In interrogating and exploring such a possibility, I deploy cosmopolitanism as a critical conceptual tool. To my mind, interrogating and applying the concepts of cosmopolitanism can categorically help understand and develop the terrains of an ethical and empathetic community building across class, caste, and other socio-cultural and geographic matrices. Within the realities of a growing global sphere, this kind of an interrogation can help support a global civic culture while laying the foundations of a cosmopolitan democracy. I take Monsoon Wedding as a premise marking tensions within group and individual interactions while exploring this potential of community building.
Mapping the Whole-Body Muscle Activity of Hydra vulgaris

Hydra is a cnidarian polyp with an anatomically simple neuromuscular system that can offer evolutionary insights on the functional design of animal body plans. Using calcium imaging to map the activity of the entire epitheliomuscular system of behaving Hydra, we find seven basic spatiotemporal patterns of muscle activity. Patterns include global and local activation events with widely varying kinetics of initiation and wave-like propagation. The orthogonally oriented endodermal and ectodermal muscle fibers are jointly activated during longitudinal contractions. Individual epitheliomuscular cells can participate in multiple patterns, even with very different kinetics. This cellular multifunctionality could enable the structurally simple epitheliomuscular tissue of basal metazoans to implement a diverse behavioral output.
Ways of knowing in precision health

Precision health can provide an avenue to bridge and integrate ways of knowing for research and practice. Nurse scientists have a long-standing interest in using multiple sources of information to address research questions of significance to the profession and discipline of nursing, which can lead to much needed contributions to precision health care. In this paper, nursing scientists discuss emerging research methods including omics, electronic sensors, and geospatial data, and mixed methods that further develop nursing science and contribute to precision health initiatives. The authors provide exemplars of the types of knowledge and ways of knowing that, using these and other advanced data and analytic strategies, may advance precision health within the context of nursing science.
Intraoperative Events in Liver Transplantation Using Donation After Circulatory Death Donors.

Liver grafts from donation after circulatory death (DCD) are a source of organs to decrease wait-list mortality. While there have been lower rates of graft loss, there are concerns of an increased incidence of intraoperative events in recipients of DCD grafts. We aim to look at the incidence of intraoperative events between recipients of livers from DCD and donation after brain death (DBD) donors. We collected data for 235 DCD liver recipients between 2006 and 2017. We performed a 1:1 propensity match between these patients and patients with DBD donors. Variables included recipient age, liver disease etiology, biological Model for End-Stage Liver Disease (MELD) score, allocation MELD score, diagnosis of hepatocellular carcinoma, and year of transplantation. DCD and DBD groups had no significant differences in incidence of postreperfusion syndrome (P = 0.75), arrhythmia requiring cardiopulmonary resuscitation (P = 0.66), and treatments for hyperkalemia (P = 0.84). In the DCD group, there was a significant increase in amount of total intraoperative and postreperfusion blood products (with exception of postreperfusion packed red blood cells) utilized (P < 0.05 for all products), significant differences in postreperfusion thromboelastography parameters, as well as inotropes and vasopressors used (P < 0.05 for all infusions). There was no difference in patient (P = 0.49) and graft survival (P = 0.10) at 1, 3, and 5 years. In conclusion, DCD grafts compared with a cohort of DBD grafts have a similar low incidence of major intraoperative events, but increased incidence of transient vasopressor/inotropic usage and increased blood transfusion requirements. This does not result in differences in longterm outcomes. While centers should continue to look at DCD liver donors, they should be cognizant regarding intraoperative care to prevent adverse outcomes.
Application of trilateration and Kalman filtering algorithms to track dynamic brain deformation using sonomicrometry

Abstract Trilateration and Kalman filtering algorithms have been used in many tracking applications ranging from Global Positioning Systems to biomechanics experiments to track rigid body motion and position. Recently, a technique called sonomicrometry was used to measure the deformation of human brain tissue during an injurious impact by measuring distances between sensor pairs embedded in the parenchyma and skull. The array of measured distances were used to calculate the position of each sensor at high sampling rates to quantify brain dynamic deformation. However, non-linear trilateration and Kalman filtering algorithms, which are traditionally used to track object positions, have not been investigated for the unique application of high-rate, small displacement, and dynamic deformation data collected using sonomicrometry. The objective of this study was to compare eight trilateration and Kalman filtering algorithms to determine the most suitable method for sonomicrometry trilateration. The algorithms were tested using experimental brain deformation sonomicrometry data in which random measurement errors were intentionally introduced to evaluate the effect and robustness on tracking dynamic position. The results showed that linear least squares trilateration methods performed poorly compared to the non-linear methods. Maximum Likelihood Estimate and Kalman filtering were the best performing algorithms. The Kalman filtering method was the most suitable for tracking dynamic brain deformation using sonomicrometry because it provided an accurate estimation of dynamic position and the estimated position was insensitive to the chosen initial parameters. The algorithms and error analysis can be extended to a variety of positioning applications using sonomicrometry or similar high-rate dynamic deformation tracking.
Association of Abnormal P-Wave Indices With Dementia and Cognitive Decline Over 25 Years: ARIC-NCS (The Atherosclerosis Risk in Communities Neurocognitive Study)

Background Abnormal P‐wave indices (PWIs)—reflecting underlying left atrial abnormality—are associated with increased risk of stroke independent of atrial fibrillation. We assessed whether abnormal...
A Preliminary Study on Helium and Sulfur Ion-Irradiated BCC Iron: In Situ Tensile Testing Using a Push-To-Pull Device

Under energetic radiation exposure, significant changes in material behavior occur because of the substantial increase in the point defect population and other higher order defects. Here, we report preliminary results of a study in which an in situ transmission electron microscopy (TEM)-based push-to-pull (PTP) tensile test technique was utilized to understand the microstructure and its impact on mechanical and fracture behavior in irradiated BCC iron. Density functional theory-based calculations predict a strong segregation tendency of helium and sulfur to grain boundaries. Pure iron specimens were separately implanted with energetic helium and sulfur ions at 550°C to examine the effect of ion irradiation on the microstructure using TEM, and the mechanical response in terms of strength and embrittlement behavior using the PTP technique.
Amphitheatre-headed canyons of Southern Utah: Stratigraphic control of canyon morphology

Amphitheater-headed canyon distribution in Southern Utah is most strongly related to local stratigraphy, rather than groundwater seepage erosion.
Psychometric evaluation of the child attitude toward illness scale—sibling version

The Child Attitude Toward Illness Scale (CATIS) is an established measure of how CSHCN perceive the impact of chronic conditions on their lives. We tested the psychometric properties of the CATIS a...
Multi-Omics Database Analysis of Aminoacyl-tRNA Synthetases in Cancer

Aminoacyl-tRNA synthetases (aaRSs) are key enzymes in the mRNA translation machinery, yet they possess numerous non-canonical functions developed during the evolution of complex organisms. The aaRSs and aaRS-interacting multi-functional proteins (AIMPs) are continually being implicated in tumorigenesis, but these connections are often limited in scope, focusing on specific aaRSs in distinct cancer subtypes. Here, we analyze publicly available genomic and transcriptomic data on human cytoplasmic and mitochondrial aaRSs across many cancer types. As high-throughput technologies have improved exponentially, large-scale projects have systematically quantified genetic alteration and expression from thousands of cancer patient samples. One such project is the Cancer Genome Atlas (TCGA), which processed over 20,000 primary cancer and matched normal samples from 33 cancer types. The wealth of knowledge provided from this undertaking has streamlined the identification of cancer drivers and suppressors. We examined aaRS expression data produced by the TCGA project and combined this with patient survival data to recognize trends in aaRSs' impact on cancer both molecularly and prognostically. We further compared these trends to an established tumor suppressor and a proto-oncogene. We observed apparent upregulation of many tRNA synthetase genes with aggressive cancer types, yet, at the individual gene level, some aaRSs resemble a tumor suppressor while others show similarities to an oncogene. This study provides an unbiased, overarching perspective on the relationship of aaRSs with cancers and identifies certain aaRS family members as promising therapeutic targets or potential leads for developing biological therapy for cancer.
Modulating Catalytic Properties of Targeted Metal Cationic Centers in Nonstochiometric Mixed Metal Oxides for Electrochemical Oxygen Reduction

Efficient electrochemical transformations of molecular oxygen (oxygen reduction and evolution) for energy conversion/storage rely largely on the effective design of heterogeneous electrocatalysts. ...
Pulmonary arterial hypertension patients display normal kinetics of clot formation using thrombelastography.

Pulmonary arterial hypertension is characterized by endothelial dysfunction and microthrombi formation. The role of anticoagulation remains controversial, with studies demonstrating inconsistent ef...
Evaluation of Passive Sampling Devices as Potential Surrogates of Perchlorate Uptake into Soybean

Anion exchange membrane (AEM), Nafion® tubing, and strong anion exchange cartridges (SAX) were evaluated as passive sampling devices for perchlorate uptake in soybean (Glycine max). Plant uptake studies and AEM studies were conducted in three soil textures: Ottawa sand, silt loam soil, and sandy loam soil. Nafion® tubing and SAX experiments were only conducted in Ottawa sand. AEMs were sampled every hour for the first 12 h, then every 12 h until 72 h. Perchlorate concentrations in plant tissues, SAX, and water solution in Nafion® tubing were determined weekly for 4 weeks. In sand, the amount of perchlorate accumulated in AEM increased linearly with time. Perchlorate uptake by soybean plants was poorly described by linear regressions with perchlorate concentrations on membranes. The only significant relationship between soybean uptake and membrane uptake occurred for data from membranes buried 6–12 h in sand. Significant differences (p < 0.0001) were observed for the amount of perchlorate exchanged on AEM in the three soil textures. There were no differences in perchlorate concentrations in soybean leaves among the three soil textures. Regression analysis of perchlorate concentrations in water within Nafion® tubing and in sand solution indicted that there was a significant linear relationship between them (r 2 = 0.5132, p = 0.0006). Perchlorate was not detected in eluent of SAX. AEM demonstrated its potential to accumulate perchlorate. Nafion® tubing is not a good surrogate for plant uptake, but may be a promising PSD for soil solution. SAX may not be used as a PSD by itself.
A Novel Fiber-Optic Confocal Laser Caliper Approach for Non-Contact Optical Characterization of Silk Fibroin Thin Films Created by Riboflavin Photo-Crosslinking

Silk fibroin with its attractive combination of advanced properties is promising for regenerative treatments of corneal disorders. Novel photonics approach is used to characterize the thickness and refractive index of silk fibroin thin films photo-crosslinked with a natural photosensitizer Riboflavin.
Genetic determinants of the native collateral circulation (19.3)

Native (pre-existing) collaterals connect adjacent arterial trees and limit ischemic tissue injury. I will review recent findings that collaterals have distinct features, including a unique process of formation and specialized endothelial and smooth muscle cell phenotypes. Moreover, the number and diameter of collaterals (“extent”) in tissues varies widely among different mouse strains and healthy humans, associated with wide differences in the severity of ischemic damage. A single locus, Dce1, is responsible for ~80% of the variation in mouse. Ongoing work is seeking to identify the underlying gene(s) and pathway, and whether this locus links to variation in collateral extent in humans. If so, Dce1 and its up- and down-stream partners could provide markers for collateral abundance to help stratify patients for treatment options, to assess risk-severity before disease occurs, and to provide targets for therapies to stimulate new collateral formation. Recent studies in mice have found that such “neo-collat...
Spin dependent masses and Sim(2) symmetry

Abstract Recently, Cohen and Glashow pointed out that all known experimental tests of relativistic kinematics are consistent with invariance of physics under the four-parameter subgroup Sim ( 2 ) of the Lorentz group. The massive one-particle irreducible representations of ISim ( 2 ) , that is Sim ( 2 ) times spacetime translations, are all one-dimensional, labeled by spin along a preferred axis. Consequently particle theories based on this symmetry can accommodate lepton number conserving masses for left-handed neutrinos without the need to introduce sterile states. The same property of massive particle representations, however, also leads to the possibility that particle masses may be split within the different spins of a representation of the ordinary Poincare group. In this Letter we investigate the low-energy structure of theories with spin dependent masses and comment on the bounds on such effects.
Point-based value iteration: an anytime algorithm for POMDPs

This paper introduces the Point-Based Value Iteration (PBVI) algorithm for POMDP planning. PBVI approximates an exact value iteration solution by selecting a small set of representative belief points and then tracking the value and its derivative for those points only. By using stochastic trajectories to choose belief points, and by maintaining only one value hyper-plane per point, PBVI successfully solves large problems: we present results on a robotic laser tag problem as well as three test domains from the literature.
Determinant factors and choice intention for Chinese restaurant dining: a multivariate approach.

Abstract The purpose of this study is to identify important selection attributes for customers dining at Chinese restaurants in the state of Indiana, and the determinant and predicting factors in customers' intentions to return. A closed-ended questionnaire was used, and a systematic sampling approach was employed to survey a sample of customers in three Chinese restaurants in Indiana. The data were analyzed using factor and multiple regression analysis. A four-dimensional structure was established from 14 selection attributes. The results of the study indicated four dimensions that were significantly related to the likelihood of customers returning to the same restaurants, as follows: “Food and Environment,” “Service and Courtesy,” “Price and Value,” and “Location, and Advertising and Promotion.”
Ribosomal Proteins Involved in the Suppression of Streptomycin Dependence in Escherichia coli

Suppression of streptomycin dependence in Escherichia coli strain K-114, a spectinomycin-sensitive strain, is correlated with modification of 30S ribosomal protein P4, the component modified in spectinomycin-resistant mutants. The mutant is unusual in that reversion from dependence has previously been correlated only with modification in 30S protein P4a. Introduction into K-114 of another mutation conferring spectinomycin resistance results in a further alteration in protein P4.
The Sulzer Hexis Pre‐Series Product Hxs‐1000

In the past years, Sulzer Hexis has been conducting a series of field tests for its 1kW electric SOFC co-generation unit. These tests were primarily undertaken to test functionality of the Hexis SOFC stack and identify system requirements dictated by real service environments. In preparation for industrial manufacturing planned in 2004, Sulzer Hexis is developing and testing manufacturing techniques that will enable the production of large numbers of reliable SOFC co-generation units. An introductory phase, extending from 2001 to 2003, will introduce a highly integrated pre-series product, the HXS 1000 PREMIERE, where many fabrication steps involved in its production have been automated.
COLD STARTING CHARACTERISTICS OF TAR SANDS FUELS IN A SWIRL CHAMBER AUTOMOTIVE DIESEL ENGINE

A swirl chamber automotive diesel engine was tested with five different fuels in order to evaluate the cold starting performance of tar sands derived diesel fuels which have higher aromatic contents with wider boiling ranges and lower cetane numbers. Higher aromatic content is expected to deteriorate the cold starting performance due to increased ignition delay periods; on the other hand low initial boiling point improves cold starting. Cold starting trials were performed in a temperature controlled cold chamber capable of temperatures down to -38/sup 0/C. Extensive data were obtained for five fuels using two types of injection nozzles. Data presented include glow plug warm-up times as a function of temperature, engine cranking speeds at various ambient temperatures at which cold start attempts were made, and minimum starting temperatures and cranking speeds for different glow plug heating times.
Appendix C: String Operators and Methods

This documentation was generated from the Python documentation available by typing help(str) in the Python shell.
Interpretation of Extragalactic Jets

The nature of extragalatic radio jets is modeled. The basic hypothesis of these models is that extragalatic jets are outflows of matter which can be described within the framework of fluid dynamics and that the outflows are essentially continuous. The discussion is limited to the interpretation of large-scale (i.e., kiloparsec-scale) jets. The central problem is to infer the physical parameters of the jets from observed distributions of total and polarized intensity and angle of polarization as a function of frequency. 60 refs., 6 figs.
Abstract 107: Decade Long Trends (1999 - 2009) in Pre-hospital Delay and Short-term Mortality in Patients Hospitalized for Acute Myocardial Infarction - The Worcester Heart Attack Study

Objective: Patients experiencing signs and symptoms of an acute myocardial infarction (AMI) require prompt evaluation and treatment. There are little contemporary data, however, available on how the extent of delay between the onset of acute coronary symptoms and hospital presentation may impact short-term mortality. The purpose of this population-based study was to examine the relationship between extent of pre-hospital delay with hospital case-fatality rates (HCFRs) and 30-day post-admission mortality rates (PAMRs) among patients hospitalized with validated AMI in all central Massachusetts medical centers, and trends over time therein. Methods: We examined the medical records of residents of the Worcester, MA, metropolitan area hospitalized with a confirmed AMI at all 11 central MA medical centers on a biennial basis between 1999 and 2009 (n = 6,017). Information on patient’s demographic, medical history, clinical characteristics, and time of acute symptom onset and hospital arrival was abstracted. Resu...
Historical Translation: Pseudo-Dionysius, Thomas Aquinas, and the Unknown God

This chapter defines the interpretation of past statements as ‘historical translation’ and identifies such translation as constitutive of religious traditions. Applying translation theory to religion, this chapter then uses George Steiner’s view of language to trace the loss and gain in meaning in Thomas Aquinas’s historical translation of Pseudo-Dionysius’s statement that God is known as unknown. Since Thomas’s historical translation of Pseudo-Dionysius is one instance of a process constitutive of Christianity as a historical tradition, it follows that the Christian tradition, viewed through Steiner’s theory, perpetuates itself through constant change.
Effects of overflights on incubating Wilson's plover behavior and heart rate

Increasing attention is paid to the effects of human activities, including the use of aircraft, on wildlife. However, responses to visual and auditory stimuli associated with aircraft are highly species- and context-dependent and results of existing studies should not be generalized across species, or even across life stages of the same species. We used digital audio recorders, auto-triggered cameras, and heart rate monitors to study the responses of nesting Wilson's plovers (Charadrius wilsonia) to different types of planes (civilian and military fixed-wing aircraft) and helicopters (civilian and military rotary-wing aircraft) at Cape Lookout National Seashore, North Carolina. We compared vigilance behavior, incubation rate, and heart rate before, during, and after overflights. Wilson's plovers were alert and scanned more during military rotary-wing overflights, and scanned more during both military and civilian fixed-wing overflights than during periods without overflights. Heart rates and incubation rates did not change during any type of overflights. Although we found no direct link between increased vigilance rates and decreased reproductive success, a substantial increase in aircraft traffic at our study site, especially rotary-wing overflights, would merit further investigation. © 2015 The Wildlife Society.