cssi/SciSciGPT-SciSciNet huggingface dataset:
Anti-ovarian and anti-lymphocyte antibodies in patients with chronic vaginal candidiasis

Seventeen of 30 patients with chronic vaginal candidiasis (CVC) of at least 5 years duration had varying degrees of menstrual problems and defective T lymphocyte function; 8 developed amenorrhea. In a group of 40 CVC patients, titers of autoantibodies to ovary, thymocytes, a T-cell line (CCRF-CEM), and a B-cell line (RN114) were significantly higher than those in 45 normal females (69 +/- 3 vs. 5 +/- 2, 70 +/- 27 vs. 4 +/- 2, l7 +/- 6, vs. 4 +/ 2, and 73 +/- 24 vs. 8 +/- 5, respectively, mean +/- S.E.). Antibody titers to sperm, T-cell line HSB-2, and B-cell lines RAJI and BALL-1 were within the normal range. Significant correlations were found between anti-Candida, anti-ovarian, and anti-thymocyte antibody titers. Similar results were found for 6 patients with chronic mucocutaneous candidiasis (CMCC) and in serial samples obtained over a one-year period from a representative patient with both CVC and CMCC. The anti-T-lymphocyte antibodies in these patients were directed primarily against non-suppressor (predominately helper) T cells. Absorption of the sera with either Candida cells, ovarian follicle cells, or thymocytes reduced all three antibody titers; absorption with sperm or B-cell lines did not alter the titers. These results suggest the presence of one or more cross-reactive antigens on ovarian follicle, T lymphocytes (especially the helper cell subpopulation), and Candida.
Genetic algorithm based coil system optimization for wireless power charging of electric vehicles

High efficiency and low cost coil system design is one of the key points for wireless power transfer. In this paper, along with a design example and experimental verification, a novel optimization method with generic algorithm is presented. The coil track layouts are interpreted with binary strings in the design iterations. Some practical considerations and detailed implementations are introduced in the optimization procedure.
Increased endothelial uptake of paclitaxel as a potential mechanism for its antiangiogenic effects: Potentiation by Cox-2 inhibition

Paclitaxel has antiangiogenic properties, but the mechanisms for the enhanced sensitivity of endothelial cells (ECs) to this drug are not established. The aims of our study were to compare the distribution of paclitaxel into ECs with other cell types, to assess the effects of low doses of paclitaxel on Cox-2 expression and to determine the combined effects of paclitaxel and Cox-2 inhibitors on angiogenesis in vitro and in patients with cancer. Upon exposure to low (5 nM) concentrations of [3H]-paclitaxel, uptake of radioactivity was more than 5 times higher in ECs than other cell types. Exposing human umbilical vein ECs to low nanomolar (1-50 nM) concentrations of paclitaxel enhanced Cox-2 expression more than 2-fold, as measured by ELISA. Combined treatment with paclitaxel and the Cox-2 inhibitor NS-398 resulted in increased antiendothelial effects as compared to each agent alone. To assess the biologic effects of the combined treatment in vivo, 4 cancer patients were treated with a prolonged intravenous infusion of paclitaxel (10 mg/m2/day) and the Cox-2 inhibitor celecoxib (400 mg p.o. BID), and plasma angiogenic activity and drug levels were measured. The treatment was well tolerated, providing steady-state concentrations of paclitaxel in plasma near 10 nM and potent plasma antiendothelial effects were observed. These findings suggest that antiangiogenic effects of paclitaxel may be due its preferential accumulation in ECs. Low dose paclitaxel in combination with a Cox-2 inhibitor is an attractive antiangiogenic and antitumor strategy that deserves further evaluation in clinical trials.
Photo-Based Three Dimensional Graphics Models For Multi-Sensor Simulation.

A methodology has been developed and demonstrated for semi-automated generation of high fidelity terrain databases suitable for flight simulator applications. The technique has been demonstrated using electro-optic (EO), IR, and Synthetic Aperture Radar (SAR) sensor imagery. Extensions of the methodology are described for the generation of sensor image-based representations of vegetation terrain features. In contrast to polygon based databases in use by many simulators today, the simulator databases described here are gridded in nature. Finally, a realtime image generation architecture capable of exploiting this new database technology is currently in development, and is briefly summarized here.
Management of symphyseal and parasymphyseal mandibular fractures

The optimal management of symphyseal and parasymphyseal fractures continues to evolve. Fractures in this area of the mandible predispose the patients to malocclusion and widening of the face if not properly treated. The current understanding of the biomechanics and fracture healing of the mandible has influenced the modern approach to the open reduction and internal fixation of these fractures. This article will summarize the treatment approaches and the surgical caveats that will contribute to the successful treatment of fractures of the mandibular symphysis and parasymphysis.
Elevated serum uric acid.

L'hyperinsulinisme diminue les glycemies et c'est l'insulino-resistance qui est responsable des taux eleves d'acide urique
Development of high critical current densities in niobium 46.5 wt% titanium

Abstract A systematic investigation of the effects of varying the heat treatment time and temperature over a wide range in a series of composites made from high homogeneity Nb 46.5 wt% Ti has been made. The study has been confined to processes involving two or three heat treatments since these are most compatible with industrial scale fabrication. Very high J c values have been obtained using process variables significantly different from those normally used. In particular, we find that increasing the heat treatment temperature and the final drawing strain are very helpful in raising J c . The maximum J c values (at a sensitivity of 10 −14 Ωm) of 3680 Amm −2 (5 T, 4.2 K) and 1560 Amm −2 (8 T, 4.2 K) were obtained for heat treatments at 420°C and for final drawing strains > 5.
Course of cognitive impairment following attempted suicide in older adults

OBJECTIVE: Cognitive impairment has been associated with late-life suicidal behavior. Without longitudinal data it is unclear whether these are transient features of a depressive state or stable impairments. We examined longitudinally the course of cognitive impairment in older adults with depression and a history of suicide attempt. METHODS: We investigated the persistence of cognitive impairment over time in 198 depressed older adults (age >60); 91 suicide attempters, 39 depressed individuals with suicidal ideation (ideators), and 68 non-suicidal depressed adults assessed over a 2-year period at four time points. We used linear mixed effects modeling to examine group differences in trajectories of cognitive decline over 2 years, using the Mini-Mental State Examination (MMSE), Mattis Dementia Rating Scale (DRS), and Executive Interview (EXIT). RESULTS: Over the 2-year period, suicide attempters performed significantly worse than both suicide ideators and non-suicidal depressed older adults on the MMSE (mean difference: from ideators: -0.88, p = 0.02; from non-suicidal depressed: -1.52, p CONCLUSIONS: Cognitive impairment in late-life suicidal behavior appears to involve both a stable and a state-related component. Copyright © 2015 John Wiley & Sons, Ltd. Language: en
The Rights of Children, the Rights of Nations: Developmental Theory and the Politics of Children's Rights

The Convention on the Rights of the Child (CRC), U.N. General Assembly (1989) is a major breakthrough in defining children as fully human and working to ensure them the attendant benefits worldwide. While children's rights as equal human beings may seem obvious in the 21st century, the politics of establishing and ensuring such rights are contentious. The CRC is a brilliant negotiation of conceptions of the child and international relations, yet certain tensions in the children's rights process lead to a lack of clarity in a global situation that continues to leave millions of children at risk. Analyzing the CRC and related practices from a developmental perspective can help identify obstacles to the advancement of children's rights, especially those related to opportunities for rights-based thinking and the exercise of self-determination and societal-determination rights. In this article, I offer a qualitative analysis of children's rights in the context of what I refer to as the CRC activity-meaning system. I present a theoretical framework for considering this system of policy and practice as enacted in the CRC treaty and related monitoring, reporting, qualifying, and implementing documents. A discourse analysis of conceptions of the child and those responsible for ensuring their rights in seven representative documents (including the CRC Treaty, a report by the U.N. Committee on the Rights of the Child, minutes of a U.N. Security Council meeting, reports by a State-Party, and a report by a civil society group in that country) reveals tensions inherent in the CRC activity-meaning system.1 Emerging from this analysis is a tension between children's rights and nation's rights. Created in part via explicit and implicit assumptions about child development in the CRC as these posit responsibilities across actors in the broader CRC system, this tension challenges the implementation of children's rights and the development of children's rights-based understandings. I use this analysis to explain why future research and practice should address the development of children's rights-based understanding not only in terms of maturation or socialization but also as integral to salient conflicts in their every day lives.
The Argument against Using Quantitative Cultures in Clinical Trials and for the Management of Ventilator-Associated Pneumonia

Quantitative cultures have been proposed as the most accurate way to both establish the presence of ventilator-associated pneumonia (VAP) and define the etiologic pathogen. Although the clinical diagnosis of VAP has been much maligned, it may be very accurate, particularly if it is objectively defined by calculating the Clinical Pulmonary Infection Score and if the score incorporates a Gram stain of a lower respiratory tract sample. After the clinical diagnosis of VAP is made, a culture is needed to identify the etiologic pathogen, but this culture does not need to be quantitative or bronchoscopic. Quantitative culture-based diagnosis may not be more accurate than clinical diagnosis, and quantitative cultures have a number of methodologic limitations that can cause both false-positive and false-negative results. Finally, a number of studies have suggested that clinical management without quantitative cultures may be accurate and that outcomes, such as mortality and change in antibiotics to a focused regimen, are not improved by the use of quantitative cultures. In clinical trials, management using nonquantitative cultures of a tracheal aspirate specimen may be preferable. Reliance on quantitative cultures can complicate enrollment and will ensure that only a subset of patients with VAP is studied because of the relatively high false-negative rate of quantitative culture results, particularly among patients treated with antibiotics before samples are obtained.
A Graphical Sequential Weibull Life Test Procedure

This paper presents a series of graphed sequential tests to be used for testing the joint hypothesis that (the Weibull shape factor) \beta = \beta 0 and that (the Weibull scale factor) \theta = \theta 0 . These o plans, obtained by simulating life tests on an IBM 7090 computing system, are specified for two sample sizes, five confidence levels, and six shape factors ( \beta> 0 o).
Matrix Metalloproteinase Inhibition Alters Functional and Structural Correlates of Deafferentation-Induced Sprouting in the Dentate Gyrus

Molecules comprising the extracellular matrix (ECM), and the family of matrix metalloproteinases (MMPs) that regulate them, perform essential functions during neuroplasticity in both developing and adult nervous systems, including substrate guidance during neuritogenesis and the establishment of boundaries for axonal terminal fields. MMP proteolysis of ECM molecules may perform a permissive or inductive role in fiber remodeling and synaptogenesis initiated by deafferentation. This study examined functional and structural effects of MMP inhibition during the early phases of deafferentation-induced sprouting, characterizing components of the degeneration/proliferation cycle that may be dependent on MMP activity. Adult rats received unilateral lesions of the entorhinal cortex to induce collateral sprouting of the crossed temporodentate fiber pathway. This was followed by intraventricular infusion of the MMP inhibitor FN-439 (2.9 mg/kg) or saline vehicle. After 7 d postlesion, rats underwent in vivo electrophysiological recording or histological processing for electron microscopic analysis. Lesioned rats receiving vehicle exhibited normal sprouting and synaptogenesis, with the emergence of the capacity for long-term potentiation (LTP) within the sprouting pathway, and the successful clearance of degenerating terminals with subsequent synaptic proliferation. In contrast, lesioned rats receiving the MMP inhibitor failed to develop the capacity for LTP and showed persistent cellular debris. Current source density analysis also revealed an FN-439-induced disruption of the current sink, normally localized to the middle region of the granule cell dendrites, corresponding to the terminal field of the crossed temporodentate fibers. These results establish a role for MMP-dependent processes in the deafferentation/sprouting cycle.
Building sustainable communities: Immigrants and mobility in Vermont

Abstract The theory and practice of sustainability involve engaging a delicate balance between often competing interests, usually defined in terms of the ecological, economic, and social arenas. The complexities apparent in balancing such tensions become especially evident if we consider transportation equity, specifically in the context of urban planning and managing both population growth and demographic change. This paper examines issues of access, transportation, and sustainability – in its myriad forms – for refugees settling in Vermont. With relatively homogenous populations and a lack of resettlement services common to many traditional immigrant destinations, small towns in Vermont present a particular challenge for refugees arriving from diverse locations in Africa, Asia, and the Middle East. Drawing on the extant literature regarding sustainable transportation, spatial mismatch, accessibility, and environmental justice, this paper details the results of a community-based project using surveys and key informant interviews in order to explore the transportation experiences and challenges faced by refugees in Vermont. In particular, the paper looks at gaps that refugees have identified in existing infrastructure as well as modes and hierarchies of transportation choice. Additionally, the paper examines the attempt to include refugee perspectives in regional transportation planning initiatives, including one county's federally supported sustainable communities plan.
Jet-cooled vibronic spectroscopy and asymmetric torsional potentials of phenylcyclopentene

The ultraviolet spectroscopy of the S1← S0 transition of 1-phenylcyclopentene (PCP) was studied by resonant-two-photon ionization (R2PI), laser-induced fluorescence (LIF) and single vibronic level fluorescence (SVLF). UV–UV hole-burning (UVHB) spectroscopy was used to determine that there is only one spectroscopically distinct conformer in the supersonic expansion. The excitation spectrum shows extensive vibronic structure extending to over 1000 cm−1 above the electronic origin (34 646 cm−1). Much of the vibronic structure is similar to that of styrene and other singly substituted benzene derivatives, with Franck–Condon (FC) activity predominantly in substituent-sensitive benzene modes. Sizeable FC progressions were also found in the inter-ring torsion, reflecting a large displacement in the inter-ring angle upon electronic excitation. No evidence for FC activity in the ring-puckering coordinate is observed. The torsional potentials of the ground and excited states were determined from the experimental transition frequencies by fitting the calculated to the experimental torsional frequency spacings in an automated least-squares fitting procedure. The S1 torsional potential is a symmetric single-well potential centered around a locally planar equilibrium geometry at a torsional angle of ϕ = 0°. The energy levels are reproduced by a cosine term potential function with torsional parameters V2 = 3765 cm−1 and V4 = −183 cm−1. The S0 torsional potential possesses a twisted equilibrium geometry that is strongly asymmetric about ϕ = 0° due to the non-planarity of the cyclopentene ring. The best-fit potential parameters uses a sin/cos potential function (odd/even), with Ve2 = 948 cm−1, Ve4 = −195 cm−1, Vo2 = −162 cm−1 and Vo4 = −268 cm−1. The shape of the potentials are similar to those predicted by relaxed potential energy scans calculated at the DFT, CIS and TDDFT//CIS levels of theory. The change in the torsional angle ϕ upon electronic excitation was determined to be ∼15° from fits of the displacement δ of the S0 torsional potential with respect to the S1 potential. The simulated shift of the S0 potential with respect to the S1 potential of ∼15° is in very good agreement with that obtained from B3LYP calculations.
Obstetric Variation, Intervention, and Outcomes: Doing More but Accomplishing Less

Obstetric interventions, particularly induction of labor and cesarean section, are done more and more commonly, although there is a wide variation between hospitals and practitioners in specific rates. This degree of variation implies imprecision and uncertainty about diagnoses and indicated management. Although the net result of this variation has been a "more is better" approach leading to increasing use of obstetric interventions, little evidence of commensurate improvements in outcome is available. A combined package of using currently available evidence, formulating best practices, instituting regular review and feedback to hospitals and practitioners about intervention rates, and a public health approach to educate women has the potential to achieve an acceptable balance between when intervention in the labor and delivery process is warranted and when it is unnecessary.
Evidence-based medicine in otolaryngology, Part 3: everyday probabilities: diagnostic tests with binary results.

Recent studies have demonstrated that the majority of phy- sicians cannot accurately determine the predictive values of diagnostic tests. Physicians must understand the predictive probabilities associated with diagnostic testing in order to convey accurate information to patients, a key aspect of evidence-based practice. While sensitivity and specificity are widely understood, predictive values require a further understanding of conditional probabilities, pretest probabil- ities, and the prevalence of disease. Therefore, this third installment of the series ''Evidence-Based Medicine in Otolaryngology'' focuses on understanding the probabilities needed to accurately convey the results of dichotomous diagnostic tests in everyday practice.
Laparoscopic positioning and nerve injuries.

From the Department of Obstetrics and Gynecology, Wright State University Boonshoft School of Medicine, Dayton, Ohio(Drs. Barnett, Hurd, and Williams); Kalispell Regional Medical Center, Kalispell, Montana (Dr. Rogers); and theDepartment of Neurosurgery, Indiana University School of Medicine, Indianapolis, Indiana (Dr. Shapiro).
Two views of the Minahasa; or, whatever happened to the poor, heathen bushnatives?

The representation of other cultures invariably entails the presentation of selfportraits, in that those people who are observed are overshadowed or eclipsed by the observer. As a consequence the substantial presences of others are ignored or lost from view in the drama of the self seen in the imbroglio of contact. . . . What is fashioned and refashioned is a euphemization of power in that materials which ostensibly purport to describe other people are effectively concerned with European selfrepresentation. (Richards 1994, 289)
Perinatal n-3 fatty acid deficiency selectively reduces myo-inositol levels in the adult rat PFC: an in vivo 1H-MRS study

To investigate the effects of omega-3 fatty acid deficiency on phosphatidylinositol signaling in brain, myo-inositol (mI) concentrations were determined in the prefrontal cortex (PFC) of omega-3 fatty acid deficient rats by in vivo proton magnetic resonance spectroscopy (1H-MRS). To generate graded deficits in PFC docosahexaenoic acid (22:6n-3) (DHA) composition, perinatal and postweaning α-linolenic acid (18:3n-3) (ALA) deficiency models were used. Adult male rats were scanned in a 7T Bruker Biospec system and a 1H-MRS spectrum acquired from the bilateral medial PFC. Rats were then challenged with SKF83959, a selective agonist at phosphoinositide (PI)-coupled dopamine D1 receptors. Postmortem PFC fatty acid composition was determined by gas chromatography. Relative to controls, PFC DHA composition was significantly reduced in adult postweaning (−27%) and perinatal (−65%) ALA-deficiency groups. Basal PFC mI concentrations were significantly reduced in the perinatal deficiency group (−21%, P = 0.001), but not in the postweaning deficiency group (−1%, P = 0.86). Among all rats, DHA composition was positively correlated with mI concentrations and the mI/creatine (Cr) ratio. SKF83959 challenge significantly increased mI concentrations only in the perinatal deficiency group (+16%, P = 0.02). These data demonstrate that perinatal deficits in cortical DHA accrual significantly and selectively reduce mI concentrations and augment receptor-generated mI synthesis.
Duality, magnetic space group and their applications to quantum phases and phase transitions on bipartite lattices in several experimental systems

Abstract By using a dual vortex method, we study phases such as superfluid, solids, supersolids and quantum phase transitions in a unified scheme in extended boson Hubbard models at and slightly away from half filling on bipartite optical lattices such as honeycomb and square lattice. We also map out its global phase diagram at T = 0 of chemical potential versus the ratio of kinetic energy over the interaction. We stress the importance of the self-consistence condition on the saddle point structure of the dual gauge fields in the translational symmetry breaking insulating sides, especially in the charge density wave side. We find that in the translational symmetry breaking side, different kinds of supersolids are generic possible states slightly away from half filling. We propose a new kind of supersolid: valence bond supersolid (VB-SS). In this VB-SS, the density fluctuation at any site is very large indicating its superfluid nature, but the boson kinetic energies on bonds between two sites are given and break the lattice translational symmetries indicating its valence bound nature. We show that the quantum phase transitions from solids to supersolids driven by a chemical potential are in the same universality class as that from a Mott insulator to a superfluid, therefore have exact exponents z = 2 , ν = 1 / 2 , η = 0 with a logarithmic correction. Comparisons with previous quantum Monte Carlo (QMC) simulations on a square lattice are made. Implications on possible future QMC simulations in both bipartite lattices are given. All these phases and phase transitions can be potentially realized in ultra-cold atoms loaded on optical bipartite lattices. Then we apply our results to investigate the reentrant “superfluid” in a narrow region of coverages in the second layer of 4He adsorbed on graphite and the low temperature phase diagram of hydrogen physisorbed on krypton-preplated graphite (H2/Kr/graphite) near half filling. We suggest that 4He and H2 lattice supersolids maybe responsible for the experimental signals in the two systems. Finally, we suggest Cooper supersolid is repressible for the phase diagram of La2−x BaxCuO4 near x = 1 / 8 .
Connecting Antarctic Cross-Slope Exchange with Southern Ocean Overturning

Previous idealized investigations of Southern Ocean overturning have omitted its connection with the Antarctic continental shelves, leaving the influence of shelf processes on Antarctic Bottom Water (AABW) export unconsidered. In particular, the contribution of mesoscale eddies to setting the stratification and overturning circulation in the Antarctic Circumpolar Current (ACC) is well established, yet their role in cross-shelf exchange of water masses remains unclear. This study proposes a residual-mean theory that elucidates the connection between Antarctic cross-shelf exchange and overturning in the ACC, and the contribution of mesoscale eddies to the export of AABW. The authors motivate and verify this theory using an eddy-resolving process model of a sector of the Southern Ocean. The strength and pattern of the simulated overturning circulation strongly resemble those of the real ocean and are closely captured by the residualmean theory. Over the continental slope baroclinic instability is suppressed, and so transport by mesoscale eddies is reduced. This suppression of the eddy fluxes also gives rise to the steep ‘‘V’’-shaped isopycnals that characterize the Antarctic Slope Front in AABW-forming regions of the continental shelf. Furthermore, to produce water on the continental shelf that is dense enough to sink to the deep ocean, the deep overturning cell must be at least comparable in strength to wind-driven mean overturning on the continental slope. This results in a strong sensitivity of the deep overturning strength to changes in the polar easterly winds.
Mental Health in Boys and Girls: Awareness of Attitudes for Positive Sex Roles

The mental health of boys and girls can be improved through encouraging their awareness of socializing influences on their acquisition of sex roles. A complementary understanding needs to be developed in socializing agents as well. Psychologists and other social scientists have not facilitated this process — because of their own failure to address issues which underly both theory and practice. The reasons for this failure are considered and suggestions are presented for parents, educators, and social scientists to involve themselves meaningfully in the process of developing attitudes for positive sex roles.
ABNORMAL GLOBAL LONGITUDINAL STRAIN TO PREDICT OUTCOMES IN HYPERTROPHIC CARDIOMYOPATHY

Although global longitudinal strain (GLS) predicts cardiovascular morbidity and mortality in certain populations, data evaluating GLS and outcomes in hypertrophic cardiomyopathy (HCM) are limited. Currently, a combination of clinical and imaging factors are primarily used to risk stratify patients
Studies on wheat plants using carbon-14 compounds. XIX. Observations on the metabolism of lysine-C14.

When generally labelled lysine-C14 or α-aminoadipic acid-6-C14 was administered to wheat seedlings 48% and 57%, respectively, of the carbon-14 was recovered in water-soluble materials. An additiona...
Modulation of ion-channel function by G-protein-coupled receptors

Neurotransmitters acting through G-protein-coupled receptors change the electrical excitability of neurons. Activation of receptors can affect the voltage dependence, the speed of gating, and the probability of opening of various ion channels, thus changing the computational state and outputs of a neuron. Each cell expresses many kinds of receptors, and uses several intracellular signaling pathways to modulate channel function in different ways. It has become possible to dissect these pathways by combining pharmacological and biophysical experiments. Recent patch-clamp work in sympathetic neurons will be summarized to illustrate the mechanisms underlying modulation and its significance.
Fallacious argumentation in student reasoning: Are there benefits?

This article reports on an analysis of episodes of invalid or controversial arguments that occurred while two different groups of students worked on similar fraction tasks and examine the role that these types of arguments played in the development of students' reasoning. One group consisted of suburban, middle-class, fourth graders who worked on these tasks during the regular school day. The other group was comprised of sixth-graders from an urban community working on similar tasks as part of an informal learning after-school project. The findings of this study indicate that allowing students to share and discuss incorrect arguments promoted rich mathematical discourse and argumentation. The invalid arguments triggered the use of varied reasoning by other students and cleared up previous [mis]understandings.
Comparison of ventricular pressure relaxation assessments in human heart failure: quantitative influence on load and drug sensitivity analysis.

Abstract OBJECTIVES We contrasted various methods for assessing ventricular pressure decay time constants to test whether sensitivity to slight data instability or disparities between model-assumed and real decay are systematically altered by cardiac failure. We hypothesized that such discrepancies could result in apparent increased relaxation sensitivity to load and drug stimulation. BACKGROUND Deviation of relaxation behavior from model-assumed waveforms may be worsened by failure, enhancing instability and apparent load and drug sensitivity of commonly used indexes. METHODS Pressure-volume relations were measured in patients with normal (n = 14), hypertrophic (hypertrophic cardiomyopathy [HCM], n = 15) and dilated-myopathic (dilated cardiomyopathy [DCM], n = 37) hearts before and during preload reduction or inotropic stimulation. Relaxation parameters (monoexponential [ME] model assuming zero-Tlnor non-zero-TD, TFasymptote:, hybrid logistic-TL, linear-TLR, and pressure halftime-T1/2) were contrasted regarding sensitivity to slight data range manipulation and loading or drug changes. RESULTS In DCM, TDand TFprolonged 15% to 25% (p CONCLUSIONS Relaxation consistently deviates from an ME decay in DCM resulting in instability and amplified relaxation systolic load or drug dependence of ME-based indexes in failing versus control (or HCM) hearts. The hybrid-logistic method improves quantitative analyses by providing more consistent data fits with all three heart types.
Healy, William (1869–1963)

William Healy (1869–1963) worked as a psychiatrist, psychologist, and criminologist during the first half of the twentieth century, providing psychological evaluations of juvenile delinquents to juvenile courts in Chicago and Boston. Although interested in Freudian psychology and convinced that mental conflicts lay behind most delinquencies, Healy argued in his most important publication, The Individual Delinquent, that the causes of delinquency were multifaceted and that each youth represented a unique, individual combination of causative factors. Healy's research and clinical work influenced a generation of juvenile justice reformers, and the two institutions he directed served as models for child guidance clinics established in the 1920s and 1930s. Keywords: Freud, Sigmund; intelligence quotient (IQ); adolescence; child guidance; children; juvenile delinquency; psychoanalysis
Comparison of Modular Measurement Methods Based on Consistency Analysis and Sensitivity Analysis

Most modularity measures center on quantifying dependencies with components external to modules. Some modularity measures include an accounting of component similarity. What is measured as dependencies and similarities varies by measure and by context. Additionally, there is some subjectivity in the measures. Noticeably, the measures lack rigorous verification and validation. There is also a lack of quantitative comparison among the various measures. This research highlights the consistencies among the measures of modular product design and attempts to select a single measure for use in future applications. A list of eight alternative modularity measures was developed from available literature. The goal was to compare these measures to find the most representative measure with high similarity to the mainstream of all measures but also with a high sensitivity to changes in modularity. Our hypothesis is that, since many measures look somewhat similar, we are looking for one measure that is in agreement with most measures and therefore performs reliably; it should also be significantly more sensitive. Similarity was defined via consistency analysis — similar measurements rank the different product modularities in the same sequence. Sensitivity was compared by slightly changing the product architecture of example products and then quantifying which measures are more sensitive to these changes. Analysis was based on 11 products: a Fisher-price Chatter Radio, a Proctor Silex automatic drip coffeemaker, a Johnson fishing reel with pre-spooled line, a Sunbeam home hair trimmer, a Farberware ice cream scoop, a Regent halogen clamp lamp, a Bell classic portable bicycle pump, a Pur faucet mount water filter, an ANCO premium wiper blade, a Kodak single-use camera, and an Adhesive Tech mini glue gun.Copyright © 2003 by ASME
Boll Weevils: Response to Light Sources and Colors on Traps ,

The response of Anthonomus grandis Boheman to colored lights in the laboratory confirmed that the 500–525-nm region of the spectrum has the greatest attraction. Poor response to red was noted in the laboratory and in the field. In the field, the response of both early- and late-season boll weevils to the traps increased as the intensity of reflected light was increased and also when the pigment more closely approached the 500–525-nm region of the spectrum. The greatest response was obtained with highly reflective daylight fluorescent pigments that had this spectral characteristic.
High thermoelectric efficiency in co-doped degenerate p-type PbTe

We explored the effect of K and K-Na substitution for Pb atoms in the lattice of PbTe, in an effort to test a hypothesis for the development of a resonant state that may enhance the thermoelectric power. At 300K the data can adequately be explained by a combination of a single and two-band model for the valence band of PbTe depending on hole density that varies in the range 1-15 × 10 19 cm -3 . A change in scattering mechanism was observed in the temperature dependence of the electrical conductivity, σ, for samples concurrently doped with K and Na which results in significantly enhanced σ at elevated temperatures and hence power factors. Thermal conductivity data provide evidence of a strong interaction between the light- and the heavy-hole valence bands at least up to 500K. Figure of merits as high as 1.3 at 700K were measured as a result of the enhanced power factors.
Mechanism of the Insecticidal Action of Mercury and Mercury Salts

The ovicidal action of mercury salts applied to the soil is due to metallic mercury in the gaseous state. The presence of mercury in the atmosphere over mixtures of soil and mercury salts has been repeatedly demonstrated. The concentration of mercury vapor was always found to correlate with the mortality of insect eggs exposed to such atmospheres. Factors affecting the reduction of mercury salts to metallic mercury were found to be (a) soil organic matter, (b) moisture, (c) soil p H, and (d) temperature.
História e reforma do sistema monetário internacional

Este artigo objetiva mostrar como os regimes monetarios internacionais bem-sucedidos possuem atributos comuns: capacidade de ajustamento de precos relativos, adesao de seus participantes a regras monetarias robustas e habilidade para conter pressoes de mercado.Abstract This paper aims to highlight three common characteristics of all satisfactory international monetary arrangements: the capacity to effect relative price adjustments, adherence by the participants to robust monetary rules, and the hability to contain market pressures.
Does exercise help in the treatment of psychiatric disorders

1. Some researchers have stated that the perception of fitness and health may be a better predictor of psychological improvements than actual cardiovascular fitness. 2. It appears reasonable to encourage patients in psychotherapy to participate in a regular exercise program. 3. Adjunct treatments such as exercise may become increasingly important and helpful in the changing health care delivery and reimbursement environment where more short-term and self-help therapies are being strongly encouraged.
A method for closed irrigation and suction therapy in deep wound infections. A preliminary report.

An improved method for closed-system, irrigation-suction, antibiotic-detergent treatment of deep infected wounds has been described. Most of the twenty-four patients in the present series had acute infections of the musculoskeletal system but there were some chronic infections. The method has been simplified by the use of a preoperatively prepared surgical pack and a crisscross flow-reversal arrangement of the tubing. Insertion of the tubes through puncture wounds at surgery is facilitated by the use of Steinmann pins of the proper diameter, which eliminate the likelihood of leakage about the tubes. It is convenient to have three intravenous bottles in place. The desired solution may be selected by appropriate application of clamps on the tubing. One intravenous bottle contains Clorpactin XCB, 0.5 per cent; another, normal saline; the third, Alevaire and the selected antibiotic in normal saline. Precautions in the use of the materials are discussed. The ability to regulate or reverse the flow of solutions precisely is increased by the crisscross tubes. The crisscross flow-reversal feature is considered essential for the prevention of pooling, sinus formation, and clogging of tubes, and as a means to assure maximum contact of the solutions with all parts of wound.
Relationship Marketing: Viewing the State-of-the-Art Across Perspectives

Relationship marketing has emerged as one of the dominant frameworks guiding marketing theory and practice. Yet, recent evidence suggests that there is no consistency in efforts at theory development in the field to date. There are several reasons for this diagnosis. First, relationship marketing has been examined from various perspectives within the field of marketing. While it is understandable that relationship marketing would focus on different issues in different contexts (e.g., services versus channels versus business-to-business markets) no synergy has developed among the various findings. Second, as a result of the compartmentalized approach, key constructs such as trust, equity, and commitment, have been operationalized many different ways. Again, this fragmentation leads to an incomplete picture and findings of limited practical application. Third, most of the scholarly research, regardless of perspective, has focused on relationship formation and not relationship maintenance, redefinition and dissolution. The primary purpose of this paper, therefore, is to develop a general theoretical framework for examining marketing relationship development as a dynamic process over which relationships continue to evolve. The proposed framework is based on the premise that the nature of dominant influencing constructs--trust, equity, and commitment, for example--change as a relationship develops, and that the relative importance of the dimensions of each construct may vary at different phases of a relationship.
Properties of Liquid He 3 at Low Temperatures

Just as liquid He4 becomes more “interesting” as the temperature is lowered below the λ-point, so also does liquid He3 begin to depart from rather classical behavior near its degeneration temperature. In this region and at lower temperatures, the nuclear spin and the antisymmetric statistics are the most notable characteristics of He3 serving to distinguish this liquid from liquid He4. In the present chapter, we propose to summarize some of the attempts that have been made at understanding the extent and nature of the roles played by these effects.
A Room at Gila Pueblo

Gila Pueblo near Globe is the type site for Gila Polychrome, and, although little published information is available, it is considered a “standard” Salado site. Excavation of one room in 1958 resul...
Effects of exercise, patient education, and resource support on women with fibromyalgia: An extended long-term study

This research examined whether a long-term, multi-component program positively affected physical fitness, pain and fatigue in seven women with fibromyalgia syndrome. These women lived independently in the community. They attended a university-based program 3 days per week, 1 hour per session, year-around for many years. They were evaluated periodically with a fitness test and rating scale regarding pain and fatigue. Results from when they began the program versus most recently are provided. All of these women showed various positive results from participation in the program.
Diagnostic accuracy of tubomanometry R value in detecting the Eustachian tube pressure equalizing function

Tubomanometry is a relatively novel Eustachian tube (ET) function testing method. A number of recent studies have utilized the R value of Tubomanometry as the main objective measure in reporting their outcome in balloon dilation of ET. There is, however, a lack of evidence concerning the reliability or validity of Tubomanometry measurements. The objectives of this study are to determine the accuracy of Tubomanometry for detecting ET opening as compared to tympanometry and determine its usefulness as a measure of ET function. Healthy subjects between ages 8 and 76 years with an intact tympanic membrane and no middle ear (ME) effusion were prospectively tested. Primary outcomes were the ET opening as determined by the Tubomanometry R value and the increase in ME pressure with tympanometry-measured in relation to a swallow at a nasopharyngeal pressure of 300 daPa. The accuracy of the tubomanometry R value for identifying a successful ET opening was made in reference to the change of ME pressure. A total of 280 measurements were available from 258 ears in 137 subjects. The presence of tubomanometry R value showed high sensitivity of detecting ET opening for the criteria of >5 daPa ME pressure increase (187/202) but low specificity for detecting ET non-opening (34/78). The R value criterion described in the original manuscripts on Tubomanometry is sensitive but not specific for ET opening. The need for validation of the tubomanometry test obviates its use as the main objective outcome measure for the balloon dilation of ET procedure.
Cytomegalovirus-Responsive CD8+ T Cells Expand After Solid Organ Transplantation in the Absence of CMV Disease.

Cytomegalovirus (CMV) is a major cause of morbidity and mortality in solid organ transplant recipients. Approximately 60% of adults are CMV seropositive, indicating previous exposure. Following resolution of the primary infection, CMV remains in a latent state. Reactivation is controlled by memory T cells in healthy individuals; transplant recipients have reduced memory T cell function due to chronic immunosuppressive therapies. In this study, CD8+ T cell responses to CMV polypeptides immediate-early-1 and pp65 were analyzed in 16 CMV-seropositive kidney and heart transplant recipients longitudinally pretransplantation and posttransplantation. All patients received standard of care maintenance immunosuppression, antiviral prophylaxis, and CMV viral load monitoring, with approximately half receiving T cell–depleting induction therapy. The frequency of CMV-responsive CD8+ T cells, defined by the production of effector molecules in response to CMV peptides, increased during the course of 1 year posttransplantation. The increase commenced after the completion of antiviral prophylaxis, and these T cells tended to be terminally differentiated effector cells. Based on this small cohort, these data suggest that even in the absence of disease, antigenic exposure may continually shape the CMV-responsive T cell population posttransplantation.
Evolution of dealloying induced strain in nanoporous gold crystals

We studied the evolution of dealloying-induced strain along the {111} in a Ag-Au nano-crystal in situ, during formation of nanoporous gold at the initial stage of dealloying using Bragg coherent X-ray diffractive imaging. The strain magnitude with maximum probability in the crystal doubled in 10 s of dealloying. Although formation of nano-pores just began at the surface, the greatest strain is located 60-80 nm deep within the crystal. Dealloying induced a compressive strain in this region, indicating volume shrinkage occurred during pore formation. The crystal interior showed a small tensile strain, which can be explained by tensile stresses induced by the non-dealloyed region upon the dealloyed region during volume reduction. A surface strain relaxation developed, attributed to atomic rearrangement during dealloying. This clearer understanding of the role of strain in the initial stages of formation of nanoporous gold by dealloying can be exploited for development of new sensors, battery electrodes, and materials for catalysis.
Romancing the Slogan

ABSTRACTThis essay argues that the Marxist discourse on slogans was shaped by Hegelian and Romantic critiques of the rationalist proposition. The first half juxtaposes Friedrich Schlegel’s account of a statement that cannot be reversed with Hegel’s doctrine of the speculative sentence. The second half focuses on Marx’s understanding of a revolutionary speech act, a salto mortale, that wins its power from the boldness with which it threatens to put our most basic model of praxis in jeopardy.
Is initial post‐disturbance regeneration indicative of longer‐term trajectories?

The ability to estimate and model future vegetation dynamics is a central focus of contemporary ecology and is essential for understanding future ecological trajectories. It is therefore critical to understand when the influence of initial post-disturbance regeneration versus stochastic processes dominates long-term post-disturbance ecological processes. Often, conclusions about post-disturbance dynamics are based upon initial regeneration in the years immediately after disturbances. However, the degree to which initial post-disturbance regeneration indicates longer-term trends is likely to be contingent on the types, intensities, and combinations of disturbances, as well as pre-disturbance ecosystem structure and composition. Our relatively limited understanding of why initial post-disturbance regeneration is sometimes a poor predictor of future ecosystem trajectories represents a critical gap in post-disturbance ecological forecasting. We studied the composition and density of regeneration of tree species following wind blowdown in 1997, wildfire in 2002, and compounded disturbances by blowdown and wildfire in subalpine forests of Colorado. We examined regeneration of Picea engelmannii, Abies lasiocarpa, Pinus contorta, and Populus tremuloides in 180 permanent plots across 12 sites (classified by pre-disturbance age and composition) in 2003, 2010, and 2015. At sites that were blown down but not burned, regeneration was dense and dominated by Picea and Abies. At these sites, regeneration observed from 2003 to 2005 (hereafter initial regeneration) was also highly predictive of regeneration 5–10 yr later. In contrast, at sites that were burned and sites that were blown down and burned, regeneration was less dense and dominated by a mix of species. At these sites, initial regeneration was a poor predictor of longer-term trends as species dominance and overall density fluctuated over the 13-yr period. These findings call into question our ability to confidently predict ecosystem trajectories based upon observations made in the years immediately after large, severe disturbances such as wildfires and compounded disturbances. As compounded disturbances become more common under climatically driven changes in disturbance regimes, post-disturbance ecosystem trajectories may become increasingly stochastic and unpredictable.