cssi/SciSciGPT-SciSciNet huggingface dataset:
Stimulated Optical Emission in Fluorescent Solids. I. Theoretical Considerations

An analysis of stimulated emission processes in fluorescent solids is presented. The kinetic equations are discussed and expressions for pumping power and effective temperature of the exciting source are given in terms of the material parameters. A comparison of excitation intensity for three- and four-level systems is given. The spectral width of the stimulated radiation is discussed with particular attention to imperfect crystals.
Worth Keeping but Not Exceeding Asymmetric Consequences of Breaking Versus Exceeding Promises

Promises are social contracts that can be broken, kept, or exceeded. Breaking one's promise is evaluated more negatively than keeping one's promise. Does expending more effort to exceed a promise lead to equivalently more positive evaluations? Although linear in their outcomes, we expected an asymmetry in evaluations of broken, kept, and exceeded promises. Whereas breaking one's promise is obviously negative compared to keeping a promise, we predicted that exceeding one's promise would not be evaluated more positively than merely keeping a promise. Three sets of experiments involving hypothetical, recalled, and actual promises support these predictions. A final experiment suggests this asymmetry comes from overvaluing kept promises rather than undervaluing exceeded promises. We suggest this pattern may reflect a general tendency in social systems to discourage selfishness and reward cooperation. Breaking one's promise is costly, but exceeding it does not appear worth the effort.
LABOR LAWS AND FIRM PERFORMANCE

U.S. labor laws impose higher costs on unionized firms in states without rightâ€ toâ€ work (RTW) laws. I find that these firms experience poor stock performance. The differenceâ€ inâ€ differences analysis comparing the effect of RTW laws on unionized and nonunionized firms shows that unionized firms in states without RTW laws underperform by about 7 percentage points per year. I find further evidence of underperformance using alternative methods to estimate abnormal stock performance, examining a natural experiment, showing expected crossâ€ sectional patterns, and assessing profitability and the market reaction to earnings announcements.
Hypoplastic Left Heart Syndrome Sequencing Reveals a Novel NOTCH1 Mutation in a Family with Single Ventricle Defects

Hypoplastic left heart syndrome (HLHS) has been associated with germline mutations in 12 candidate genes and a recurrent somatic mutation in HAND1 gene. Using targeted and whole exome sequencing (WES) of heart tissue samples from HLHS patients, we sought to estimate the prevalence of somatic and germline mutations associated with HLHS. We performed Sanger sequencing of the HAND1 gene on 14 ventricular (9 LV and 5 RV) samples obtained from HLHS patients, and WES of 4 LV, 2 aortic, and 4 matched PBMC samples, analyzing for sequence discrepancy. We also screened for mutations in the 12 candidate genes implicated in HLHS. We found no somatic mutations in our HLHS cohort. However, we detected a novel germline frameshift/stop-gain mutation in NOTCH1 in a HLHS patient with a family history of both HLHS and hypoplastic right heart syndrome (HRHS). Our study, involving one of the first familial cases of single ventricle defects linked to a specific mutation, strengthens the association of NOTCH1 mutations with HLHS and suggests that the two morphologically distinct single ventricle conditions, HLHS and HRHS, may share a common molecular and cellular etiology. Finally, somatic mutations in the LV are an unlikely contributor to HLHS.
Towards Building a Personalized Online Web Spam Detector in Intelligent Web Browsers.

Most of the extant studies about web spam detection either explicitly or implicitly assume that web spam detection is performed on the server side of a search engine. In this paper, we argue that in some scenarios, web spam detection is preferred to be conducted on the client side (e.g., intelligent web browsers). When a page is viewed using an intelligent web browser, an integrated personalized web spam detector can determine whether the page is spam or not specifically tailored to the user's judgements. We propose a framework for implementing a personalized web spam detector. The experimental results obtained from an empirical evaluation confirmed the effectiveness of the proposed personalized web spam detection method.
Unusual Causes of Increased Vascular Impedance in Renal Transplants: Duplex Doppler Evaluation

Duplex Doppler ultrasound (US) examination of the renal vasculature has proved valuable in assessing the kidney transplant. The normal renal allograft exhibits low-impedance arterial inflow similar to that seen in the normotopic kidney. The authors and others previously reported that a high vascular impedance, defined as either a pulsatility index (PI) greater than 1.8 or a resistive index greater than 0.9, indicates acute vascular rejection (AVR). Although AVR remains the most common cause of increased PI, the authors noted ten episodes among 180 serially followed-up transplants in which abnormal waveforms were clearly not due to rejection. Four other causes of increased vascular impedance are reported, including renal vein obstruction, severe acute tubular necrosis, pyelonephritis, and extrarenal compression of the graft. These new causes only slightly decrease the specificity of high vascular impedance for rejection. Furthermore, the cause can usually be recognized from the clinical history or other US findings.
Postoperative Radiation Therapy for Muscle-Invading Bladder Carcinoma

From 1974-1980, 15 patients with pT2-4 bladder carcinoma received adjuvant postoperative radiation therapy (XRT). The extent of initial surgery varied (six radical cystectomy, 5 partial cystectomy, four "total" transurethral resection). The planned XRT was 4,000-5,040 rads in 5-6 weeks to the pelvis (achieved in 14/15 patients) followed by a bladder boost in noncystectomized patients (achieved in 8/9). Survival at two years and five years was 54% (7/13 patients) and 27% (3/11 patients), respectively. Local-regional disease control (minimum two-year follow-up) was achieved in 7/11 (63%). Of seven patients alive at least two years later, small bowel complications (chronic diarrhea, obstruction) occurred in two; these latter patients each had had radical cystectomy. Adjuvant postoperative XRT may be useful in the multimodality management of patients with bladder carcinoma, especially those identified as high risk after pathologic staging and initial surgery. The poor regional control rate and relatively high incidence of complications seen in this and previous studies suggest that improved radiation technique is needed, both to ensure adequate coverage of the volume at risk and to minimize complications. Representative portals are shown to illustrate these features.
Trace metal evidence for a poorly ventilated glacial Southern Ocean

Abstract Glacial benthic δ13C and Δ14C measurements from the Atlantic Ocean have been interpreted to indicate the existence of a poorly ventilated Southern Ocean with greater CO2 and nutrient contents compared to present. Enhanced storage of CO2 in the deep ocean predicts that oxygen concentrations should have declined at the same time—a prediction increasingly supported by evidence for oxygen depletion in the glacial Southern Ocean. Here we take a novel approach by using a suite of redox-sensitive trace metals (Ag, Cd, Re and Mo) to show that Southern Ocean sediments from two cores in the Atlantic sector were suboxic during and prior to deglaciation, implying changes to ocean circulation and/or elevated export production that significantly altered deep water chemistry. In the Cape Basin, enrichments of the authigenically deposited trace metal Re are comparable to those found in oxygen minimum zones, pointing to substantial decreases in oxygenation. Furthermore, trace metal results suggest potential spatial heterogeneity in the glacial Southern Ocean, and a more complicated oceanographic and oxygenation history than has previously been assumed.
Current Status of Radionuclide Scrotal Imaging

Scrotal imaging with technetium-99m sodium pertechnetate consists of a radionuclide angiogram and static scrotal scans. Utilization of this study in patients presenting with an acute scrotum can dramatically reduce the number of surgical explorations for acute epididymitis. It can also aid in other aspects of differential diagnosis in patients presenting with either an acutely enlarged and/or painful scrotum or a scrotal mass. Ambiguities in previous descriptions of perfusion through the spermatic and extraspermatic cord vessels are described and distinguished from scrotal perfusion. The clinical and scintigraphic spectrum of testicular torsion, including spontaneous detorsion, early acute testicular torsion, midphase testicular torsion, and late phase or "missed testicular torsion," is discussed and illustrated. The variety of patterns seen in acute epididymitis, including lateral and medial epididymal location, and focal epididymitis are described, as is the appearance of hydrocele as both a primary and secondary entity. The relationship of scrotal imaging to the overall clinical presentation and evaluation of these patients is emphasized in testicular torsion, torsion of the testicular appendages, epididymitis, abscess, trauma, tumor, spermatocele, and varicocele. The techniques, clinical utility, and relationship to radionuclide imaging of Doppler ultrasound and gray scale ultrasound scanning are reviewed. Doppler ultrasound results in many false negative studies in testicular torsion. Gray scale ultrasound is useful in clarifying the nature of scrotal masses.
Chylous Ascites Following Retroperitoneal Lymph Node Dissection Successfully Treated With Peritoneovenous Shunt

A massive lymphatic leak developed following radical retroperitoneal lymph node dissection for recurrent extragonadal seminoma. Chylous ascites persisted for over 3 months, with an average daily external drainage of 1.5 liters, and was successfully treated with a peritoneovenous shunt.
Intelligent Control of a Multiactuator System

Abstract The structure of an Intelligent Multiactuator System (IMS) is discussed which is determined as a system with redundancies, where the choice between concurring alternatives appears at a definite stage as a regular procedure of system operation. The structure of the IMS is considered as a product of four hierarchies: targets, memories, propensities, and impacts. The optimum behavior is determined by anthropomorphic heuristics at the levels of planning and navigation. The optimum control of subsystems is computed at the lowest level of intelligence. The structures of optimum control are recommended which imply the online performance only for a limited amount of procedures.
Bank net worth and frustrated monetary policy

Abstract I present a model in which bank net worth determines both loan market competition and monetary transmission to firm borrowing rates. In the model, banks are local monopolists for borrowers near them. When they are flush with equity, banks expand their lending, compete for customers at the edges of their markets, and pass through changes in the monetary policy rate to their loan rates. When they lose substantial equity, banks consolidate, retreat from rivalry, and frustrate monetary transmission. The model explains why interest rate pass-through weakens after financial crises. Its predictions are consistent with several facts about bank-to-firm lending.
Random matrices in data analysis

We show how carefully crafted random matrices can achieve distance-preserving dimensionality reduction, accelerate spectral computations, and reduce the sample complexity of certain kernel methods.
Asymmetry of an Intracellular Scaffold at Vertebrate Electrical Synapses

Summary Neuronal synaptic connections are either chemical or electrical, and these two types of synapses work together to dynamically define neural circuit function [1]. Although we know a great deal about the molecules that support chemical synapse formation and function, we know little about the macromolecular complexes that regulate electrical synapses. Electrical synapses are created by gap junction (GJ) channels that provide direct ionic communication between neurons [2]. Although they are often molecularly and functionally symmetric, recent work has found that pre- and postsynaptic neurons can contribute different GJ-forming proteins, creating molecularly asymmetric channels that are correlated with functional asymmetry at the synapse [3, 4]. Associated with the GJs are structures observed by electron microscopy termed the electrical synapse density (ESD) [5]. The ESD has been suggested to be critical for the formation and function of the electrical synapse, yet the biochemical makeup of these structures is poorly understood. Here we find that electrical synapse formation in vivo requires an intracellular scaffold called Tight Junction Protein 1b (Tjp1b). Tjp1b is localized to the electrical synapse, where it is required for the stabilization of the GJs and for electrical synapse function. Strikingly, we find that Tjp1b protein localizes and functions asymmetrically, exclusively on the postsynaptic side of the synapse. Our findings support a novel model of electrical synapse molecular asymmetry at the level of an intracellular scaffold that is required for building the electrical synapse. We propose that such ESD asymmetries could be used by all nervous systems to support molecular and functional asymmetries at electrical synapses.
Classification without labels: learning from mixed samples in high energy physics

Modern machine learning techniques can be used to construct powerful models for difficult collider physics problems. In many applications, however, these models are trained on imperfect simulations due to a lack of truth-level information in the data, which risks the model learning artifacts of the simulation. In this paper, we introduce the paradigm of classification without labels (CWoLa) in which a classifier is trained to distinguish statistical mixtures of classes, which are common in collider physics. Crucially, neither individual labels nor class proportions are required, yet we prove that the optimal classifier in the CWoLa paradigm is also the optimal classifier in the traditional fully-supervised case where all label information is available. After demonstrating the power of this method in an analytical toy example, we consider a realistic benchmark for collider physics: distinguishing quark- versus gluon-initiated jets using mixed quark/gluon training samples. More generally, CWoLa can be applied to any classification problem where labels or class proportions are unknown or simulations are unreliable, but statistical mixtures of the classes are available.
Timing of Auctions of Real Options

This paper endogenizes auction timing and initiation in auctions of real options. Because bidders have information rent, a seller faces a “virtual strike price” higher than the actual exercise cost...
A Simple Antireflection Overcoat For Opaque Coatings In The Submillimeter Region

An antireflection overcoat for opaque baffle coatings in the FIR/submillimeter region has been made from a simple Teflon spray-on lubricant. The Teflon overcoat reduced the specular reflectance of four different opaque coatings by nearly a factor of two. Analysis, based on the interference term of a reflecting-layer model, indicates that in the submillimeter region the reduced reflectance depends primarily on the refractive index of the overcoat and very little on its thickness.
Exact First-Choice Product Line Optimization

Which products should a firm offer based on its customers’ preferences? This is the question posed in the problem of product line design, a well-studied and notoriously difficult problem that is ce...
Auditor Multinational Expertise and Audit Quality

ABSTRACT Over the past several decades, the scope of public companies' operations has become increasingly global. This has led to concern over the ability of audit firms to conduct high-quality aud...
Investigation of CO2 Plume Behavior for a Large-Scale Pilot Test of Geologic Carbon Storage in a Saline Formation

The hydrodynamic behavior of carbon dioxide (CO2) injected into a deep saline formation is investigated, focusing on trapping mechanisms that lead to CO2 plume stabilization. A numerical model of the subsurface at a proposed power plant with CO2 capture is developed to simulate a planned pilot test, in which 1,000,000 metric tons of CO2 is injected over a 4-year period, and the subsequent evolution of the CO2 plume for hundreds of years. Key measures are plume migration distance and the time evolution of the partitioning of CO2 between dissolved, immobile free-phase, and mobile free-phase forms. Model results indicate that the injected CO2 plume is effectively immobilized at 25 years. At that time, 38% of the CO2 is in dissolved form, 59% is immobile free phase, and 3% is mobile free phase. The plume footprint is roughly elliptical, and extends much farther up-dip of the injection well than down-dip. The pressure increase extends far beyond the plume footprint, but the pressure response decreases rapidly with distance from the injection well, and decays rapidly in time once injection ceases. Sensitivity studies that were carried out to investigate the effect of poorly constrained model parameters permeability, permeability anisotropy, and residual CO2 saturation indicate that small changes in properties can have a large impact on plume evolution, causing significant trade-offs between different trapping mechanisms.
Does Service Bundling Reduce Churn

We examine whether bundling in telecommunications services reduces churn using a series of large, independent cross sections of household decisions. To identify the effect of bundling, we construct a pseudo-panel dataset and utilize a linear, dynamic panel-data model, supplemented by nearest-neighbor matching. We find bundling does reduce churn for all three “triple-play” services. However, the effect is only “visible” during times of turbulent demand. We also find evidence that broadband was substituting for pay television in 2009. This analysis highlights that bundling helps with customer retention in service industries, and may play an important role in preserving contracting markets.
Promotional Tools Effect on Pharmaceuticals Marketing

This paper shows the effect of promotional tools on pharmaceuticals marketing. The study is based on survey method using marketing field force and their opinion in relation to the promotional tools used in pharmaceuticals marketing. This study which is primarily descriptive focuses on finding out tools used as promotional devices and their significance on marketing. The study shows that doctors detailing is the most effective tools used as promotional tool and has most significant effect on marketing. Use of product sample has also significant effect on marketing subsequent to the doctors detailing. In addition to that, pharmaceuticals' marketing has been positively influenced by the corporate presence in different health related activities like CME programs, health camps where multiple promotional effects have been made. CME programs and health camps tools have been more successful in effective marketing especially on specialty products like: anti-diabetics, anti-psychiatric, and cardiac products etc. The Saptagandaki Journal Vol.8 2017: 79-84
A High-fat, High-sugar 'Western' Diet Alters Dorsal Striatal Glutamate, Opioid, and Dopamine Transmission in Mice.

Understanding neuroadaptations involved in obesity is critical for developing new approaches to treatment. Diet-induced neuroadaptations within the dorsal striatum have the capacity to drive excessive food seeking and consumption. Five-week-old C57BL/6J mice consumed a high-fat, high-sugar 'western diet' (WD) or a control 'standard diet' (SD) for 16 weeks. Weight gain, glucose tolerance, and insulin tolerance were measured to confirm an obese-like state. Following these 16 weeks, electrophysiological recordings were made from medium spiny neurons (MSNs) in the medial (DMS) and lateral (DLS) portions of dorsal striatum to evaluate diet effects on neuronal excitability and synaptic plasticity. In addition, fast-scan cyclic voltammetry evaluated dopamine transmission in these areas. WD mice gained significantly more weight and consumed more calories than SD mice and demonstrated impaired glucose tolerance. Electrophysiology data revealed that MSNs from WD mice demonstrated increased AMPA-to-NMDA receptor current ratio and prolonged spontaneous glutamate-mediated currents, specifically in the DLS. Evoked dopamine release was also significantly greater and reuptake slower in both subregions of WD striatum. Finally, dorsal striatal MSNs from WD mice were significantly less likely to demonstrate mu-opioid receptor-mediated synaptic plasticity. Neuronal excitability and GABAergic transmission were unaffected by diet in either striatal subregion. Our results demonstrate that a high-fat, high-sugar diet alters facets of glutamate, dopamine, and opioid signaling within the dorsal striatum, with some subregion specificity. These alterations within a brain area known to play a role in food motivation/consumption and habitual behavior are highly relevant for the clinical condition of obesity and its treatment.
The Tortoise and the Hare: Interactions between Reinforcement Learning and Working Memory.

Learning to make rewarding choices in response to stimuli depends on a slow but steady process, reinforcement learning, and a fast and flexible, but capacity-limited process, working memory. Using ...
The Impact of Public Pension Funds and Other Limited Partners on the Governance of Venture Capital Funds

We examine whether the reinvestment choices of public pension funds (PPFs) affect the governance of venture capital funds. We start with a hand-collected dataset of litigation against venture capit...
Optimizing Polynomial Convolution for NTRUEncrypt

$\sf{ NTRUEncrypt}$ is one of the most promising candidates for quantum-safe cryptography. In this paper, we focus on the $\sf{ NTRU743}$ parameter set. We give a report on all known attacks against this parameter set and show that it delivers 256 bits of security against classical attackers and 128 bits of security against quantum attackers. We then present a parameter-dependent optimization using a tailored hierarchy of multiplication algorithms as well as the Intel AVX2 instructions, and show that this optimization is constant-time. Our implementation is two to three times faster than the reference implementation of $\sf{ NTRUEncrypt}$ .
Endoscopic tumor diagnosis and treatment.

This year’s Digestive Disease Week (May 18 – 21, 2013, Orlando, Fla) presented new perspectives on endoscopic diagnosis and management of GI tumors. These abstracts can be broadly divided into tumors of the upper and lower GI tract and pancreatobiliary tumors.
Why value values

Doris argues that an agent is responsible for her behavior only if that behavior expresses (a relevant subset of) the agent's values. This view has problems explaining responsibility for mistakes or episodes of forgetfulness. These problems highlight a conceptual problem with Doris's theory of responsible agency and give us reasons to prefer an alternative (non-valuational) theory of responsible agency.
Hemostasis biomarkers and incident cognitive impairment: the REGARDS study.

Essentials Cognitive disorders are increasing and vascular risk factors play a role in this. We performed a nested case control study of hemostasis biomarkers and cognitive impairment (CI). Higher baseline fibrinogen, factor VIII and D-dimer were related to incident CI over 3.5 years. Adjusted for other risk factors, 2+ abnormal markers (but not single ones) led to higher risk. SUMMARY Background Vascular risk factors are associated with cognitive impairment, a condition that imposes a substantial public health burden. We hypothesized that hemostasis biomarkers related to vascular disease would be associated with the risk of incident cognitive impairment. Methods We performed a nested case-control study including 1082 participants with 3.5 years of follow-up in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study, a longitudinal cohort study of 30 239 black and white Americans aged ≥ 45 years. Participants were free of stroke or cognitive impairment at baseline. Baseline D-dimer, fibrinogen, factor VIII and protein C levels were measured in 495 cases who developed cognitive impairment during follow-up (based on abnormal scores on two or more of three cognitive tests) and 587 controls. Results Unadjusted odds ratios (ORs) for incident cognitive impairment were 1.32 (95% confidence interval [CI] 1.02-1.70) for D-dimer > 0.50 μg mL-1 , 1.83 (95% CI 1.24-2.71) for fibrinogen > 90th percentile, 1.63 (95% CI 1.11-2.38) for FVIII > 90th percentile, and 1.10 (95% CI 0.73-1.65) for protein C < 10th percentile. There were no differences in associations by race or region. Adjustment for demographic, vascular and health behavior risk factors attenuated these associations. However, having at least two elevated biomarkers was associated with incident cognitive impairment, with an adjusted OR of 1.73 (95% CI 1.10-2.69). Conclusion Elevated D-dimer, fibrinogen and FVIII levels were not associated with the occurrence of cognitive impairment after multivariable adjustment; however, having at least two abnormal biomarkers was associated with the occurrence of cognitive impairment, suggesting that the burden of these biomarkers is relevant.
New Approach for Simulating Groundwater Flow in Discrete Fracture Network

AbstractIn this study, a new approach is developed to compute groundwater flow rate and hydraulic head distribution in a two-dimensional discrete fracture network (DFN) in which both laminar and in...
Are Recessions Good for Government Hires? The Effect of Unemployment on Public Sector Human Capital

Abstract Utilizing a large dataset on U.S. federal government employees covering 24 years, we estimate and analyze the persistent wage effect of entering government employment during recessions for recent college graduates and other new employees. Contrary to previous results in the literature for private sector employees, we document a significant and long-term wage increase for federal civil servants who enter government service in recessions. We show this result is robust to alternative samples and model specifications. We examine the role of agency occupation composition and job matching as mechanisms for these results.
Born to Take Risk? The Effect of CEO Birth Order on Strategic Risk Taking

The importance of birth order has been the subject of debate for centuries, and has captured the attention of the general public and researchers alike. Despite this interest, scholars have little u...
Validation and Inference of Schema-Level Workflow Data-Dependency Annotations

An advantage of scientific workflow systems is their ability to collect runtime provenance information as an execution trace. Traces include the computation steps invoked as part of the workflow run along with the corresponding data consumed and produced by each workflow step. The information captured by a trace is used to infer “lineage” relationships among data items, which can help answer provenance queries to find workflow inputs that were involved in producing specific workflow outputs. Determining lineage relationships, however, requires an understanding of the dependency patterns that exist between each workflow step’s inputs and outputs, and this information is often under-specified or generally assumed by workflow systems. For instance, most approaches assume all outputs depend on all inputs, which can lead to lineage “false positives”. In prior work, we defined annotations for specifying detailed dependency relationships between inputs and outputs of computation steps. These annotations are used to define corresponding rules for inferring fine-grained data dependencies from a trace. In this paper, we extend our previous work by considering the impact of dependency annotations on workflow specifications. In particular, we provide a reasoning framework to ensure the set of dependency annotations on a workflow specification is consistent. The framework can also infer a complete set of annotations given a partially annotated workflow. Finally, we describe an implementation of the reasoning framework using answer-set programming.
Evaluating the Functional Pore Size of Chloroplast TOC and TIC Protein Translocons: Import of Folded Proteins.

The degree of residual structure retained by proteins while passing through biological membranes is a fundamental mechanistic question of protein translocation. Proteins are generally thought to be unfolded while transported through canonical proteinaceous translocons, including the translocons of the outer and inner chloroplast envelope membranes (TOC and TIC). Here, we readdressed the issue and found that the TOC/TIC translocons accommodated the tightly folded dihydrofolate reductase (DHFR) protein in complex with its stabilizing ligand, methotrexate (MTX). We employed a fluorescein-conjugated methotrexate (FMTX), which has slow membrane transport rates relative to unconjugated MTX, to show that the rate of ligand accumulation inside chloroplasts is faster when bound to DHFR that is actively being imported. Stromal accumulation of FMTX is ATP dependent when DHFR is actively being imported but is otherwise ATP independent, again indicating DHFR/FMTX complex import. Furthermore, the TOC/TIC pore size was probed with fixed-diameter particles and found to be greater than 25.6 A, large enough to support folded DHFR import and also larger than mitochondrial and bacterial protein translocons that have a requirement for protein unfolding. This unique pore size and the ability to import folded proteins have critical implications regarding the structure and mechanism of the TOC/TIC translocons.
Topological Bands and Triply Degenerate Points in Non-Hermitian Hyperbolic Metamaterials

Hyperbolic metamaterials (HMMs), an unusual class of electromagnetic metamaterials, have found important applications in various fields due to their distinctive properties. A surprising feature of HMMs is that even continuous HMMs can possess topological edge modes. However, previous studies based on equal-frequency surface (analogy of Fermi surface) may not correctly capture the topology of entire bands. Here we develop a topological band description for continuous HMMs that can be described by a non-Hermitian Hamiltonian formulated from Maxwell's equations. We find two types of three-dimensional non-Hermitian triply degenerate points with complex linear dispersions and topological charges $\ifmmode\pm\else\textpm\fi{}2$ and 0 induced by chiral and gyromagnetic effects. Because of the photonic nature, the vacuum band plays an important role for topological edge states and bulk-edge correspondence in HMMs. The topological band results are numerically confirmed by direct simulation of Maxwell's equations. Our work presents a general non-Hermitian topological band treatment of continuous HMMs, paving the way for exploring interesting topological phases in photonic continua and device implementations of topological HMMs.
Demand Effects of the Internet-of-Things Sales Channel: Evidence from Automating the Purchase Process

The internet of things (IoT) is rapidly becoming one of the most popular emerging technologies in business and society. One of the major verticals that has recently begun to effectively use IoT tec...
Obesity and childhood asthma.

Purpose of reviewAsthma is a common chronic disease of the airways characterized by recurrent respiratory symptoms, bronchoreactivity, and airway inflammation. The high toll on quality of life has led to sustained efforts to understand the factors leading to asthma inception and poor disease control
Efficacy and Safety of Pediatric Critical Care Physician Telemedicine Involvement in Rapid Response Team and Code Response in a Satellite Facility.

Objectives Satellite inpatient facilities of larger children's hospitals often do not have on-site intensivist support. In-house rapid response teams and code teams may be difficult to operationalize in such facilities. We developed a system using telemedicine to provide pediatric intensivist involvement in rapid response team and code teams at the satellite facility of our children's hospital. Herein, we compare this model with our in-person model at our main campus. Design Cross-sectional. Setting A tertiary pediatric center and its satellite facility. Patients Patients admitted to the satellite facility. Interventions Implementation of a rapid response team and code team model at a satellite facility using telemedicine to provide intensivist support. Measurements and main results We evaluated the success of the telemedicine model through three a priori outcomes: 1) reliability: involvement of intensivist on telemedicine rapid response teams and codes, 2) efficiency: time from rapid response team and code call until intensivist response, and 3) outcomes: disposition of telemedicine rapid response team or code calls. We compared each metric from our telemedicine model with our established main campus model. Main results Critical care was involved in satellite campus rapid response team activations reliably (94.6% of the time). The process was efficient (median response time 7 min; mean 8.44 min) and effective (54.5 % patients transferred to PICU, similar to the 45-55% monthly rate at main campus). For code activations, the critical care telemedicine response rate was 100% (6/6), with a fast response time (median 1.5 min). We found no additional risk to patients, with no patients transferred from the satellite campus requiring a rapid escalation of care defined as initiation of vasoactive support, greater than 60 mL/kg in fluid resuscitation, or endotracheal intubation. Conclusions Telemedicine can provide reliable, timely, and effective critical care involvement in rapid response team and Code Teams at satellite facilities.
Choice-related activity during visual slant discrimination in macaque CIP but not V3A

Creating three-dimensional (3D) representations of the world from two-dimensional retinal images is fundamental to visually guided behaviors including reaching and grasping. A critical component of this process is determining the 3D orientation of objects. Previous studies have shown that neurons in the caudal intraparietal area (CIP) of the macaque monkey represent 3D planar surface orientation (i.e., slant and tilt). Here we compare the responses of neurons in areas V3A (which is implicated in 3D visual processing and precedes CIP in the visual hierarchy) and CIP to 3D-oriented planar surfaces. We then examine whether activity in these areas correlates with perception during a fine slant discrimination task in which the monkeys report if the top of a surface is slanted toward or away from them. Although we find that V3A and CIP neurons show similar sensitivity to planar surface orientation, significant choice-related activity during the slant discrimination task is rare in V3A but prominent in CIP. These results implicate both V3A and CIP in the representation of 3D surface orientation, and suggest a functional dissociation between the areas based on slant-related choice signals.
The more things change, the more they stay the same: Developing countries’ unity at the nexus of trade and environmental policy

The term “global South” refers to developing countries as a whole, but recently, numerous developing countries – Brazil, China, India, Indonesia, Mexico, Nigeria, Thailand, South Africa, and others – simultaneously grew wealthier while many other countries remain poor. This prompts a fundamental question: does the global South demonstrate unity in international politics, with developing countries at various wealth levels behaving like one another, and in ways unlike the industrialized “North”? Or is the global South fractured, too economically and politically diverse to operate in tandem? Theoretical expectations are mixed, and the empirical record is inconclusive. To adjudicate, we pinpoint a stringent set of observable implications that should hold if the developing world is to be considered at all unified vis-a-vis the industrialized world. Then we probe those implications with statistical analyses of over 3,600 paragraphs of text from governments’ negotiations concerning trade and environmental policy, a policy space that facilitates generalizability by representing fundamental sovereignty and wealth issues underlying traditional North-South frictions. Our finding – that overall, developing countries exhibit surprising unity – weighs in on central theoretical and policy debates in international relations, comparative politics, and political economy.
Secure Distributed Key Generation for Discrete-Log Based Cryptosystems

A Distributed Key Generation (DKG) protocol is an essential component of threshold cryptosystems required to initialize the cryptosystem securely and generate its private and public keys. In the case of discrete-log-based (dlog-based) threshold signature schemes (ElGamal and its derivatives), the DKG protocol is further used in the distributed signature generation phase to generate one-time signature randomizers (r = gk). In this paper we show that a widely used dlog-based DKG protocol suggested by Pedersen does not guarantee a uniformly random distribution of generated keys: we describe an efficient active attacker controlling a small number of parties which successfully biases the values of the generated keys away from uniform. We then present a new DKG protocol for the setting of dlog-based cryptosystems which we prove to satisfy the security requirements from DKG protocols and, in particular, it ensures a uniform distribution of the generated keys. The new protocol can be used as a secure replacement for the many applications of Pedersen's protocol. Motivated by the fact that the new DKG protocol incurs additional communication cost relative to Pedersen's original protocol, we investigate whether the latter can be used in specific applications which require relaxed security properties from the DKG protocol. We answer this question affirmatively by showing that Pedersen's protocol suffices for the secure implementation of certain threshold cryptosystems whose security can be reduced to the hardness of the discrete logarithm problem. In particular, we show Pedersen's DKG to be sufficient for the construction of a threshold Schnorr signature scheme. Finally, we observe an interesting trade-off between security (reductions), computation, and communication that arises when comparing Pedersen's DKG protocol with ours.
Generic zero-cost reuse for dependent types

Dependently typed languages are well known for having a problem with code reuse. Traditional non-indexed algebraic datatypes (e.g. lists) appear alongside a plethora of indexed variations (e.g. vectors). Functions are often rewritten for both non-indexed and indexed versions of essentially the same datatype, which is a source of code duplication. We work in a Curry-style dependent type theory, where the same untyped term may be classified as both the non-indexed and indexed versions of a datatype. Many solutions have been proposed for the problem of dependently typed reuse, but we exploit Curry-style type theory in our solution to not only reuse data and programs, but do so at zero-cost (without a runtime penalty). Our work is an exercise in dependently typed generic programming, and internalizes the process of zero-cost reuse as the identity function in a Curry-style theory.
Computational geometry

The class of n2-hard geometric problems is described, with special concentration on detecting collinearities among a set of points in the plane.
Controlled growth of imine-linked two-dimensional covalent organic framework nanoparticles

Covalent organic frameworks (COFs) consist of monomers arranged in predictable structures with emergent properties. However, improved crystallinity, porosity, and solution processability remain major challenges. To this end, colloidal COF nanoparticles are useful for mechanistic studies of nucleation and growth and enable advanced spectroscopy and solution processing of thin films. Here we present a general approach to synthesize imine-linked 2D COF nanoparticles and control their size by favoring imine polymerization while preventing the nucleation of new particles. The method yields uniform, crystalline, and high-surface-area particles and is applicable to several imine-linked COFs. In situ X-ray scattering experiments reveal the nucleation of amorphous polymers, which crystallize via imine exchange processes during and after particle growth, consistent with previous mechanistic studies of imine-linked COF powders. The separation of particle formation and growth processes offers control of particle size and may enable further improvements in crystallinity in the future.
Learning the LMP-load coupling from data: A support vector machine based approach

This paper investigates the fundamental coupling between loads and locational marginal prices (LMPs) in securityconstrained economic dispatch (SCED). Theoretical analysis based on multi-parametric programming theory points out the unique one-to-one mapping between load and LMP vectors. Such one-to-one mapping is depicted by the concept of system pattern region (SPR) and identifying SPRs is the key to understanding the LMP-load coupling. Built upon the characteristics of SPRs, the SPR identification problem is modeled as a classification problem from a market participant's viewpoint, and a Support Vector Machine based data-driven approach is proposed. It is shown that even without the knowledge of system topology and parameters, the SPRs can be estimated by learning from historical load and price data. Visualization and illustration of the proposed datadriven approach are performed on a 3-bus system as well as the IEEE 118-bus system.
Snakes partition their body to traverse large steps stably

ABSTRACT Many snakes live in deserts, forests and river valleys and traverse challenging 3-D terrain such as rocks, felled trees and rubble, with obstacles as large as themselves and variable surface properties. By contrast, apart from branch cantilevering, burrowing, swimming and gliding, laboratory studies of snake locomotion have focused on locomotion on simple flat surfaces. Here, to begin to understand snake locomotion in complex 3-D terrain, we studied how the variable kingsnake, a terrestrial generalist, traversed a large step of variable surface friction and step height (up to 30% snout–vent length). The snake traversed by partitioning its body into three sections with distinct functions. Body sections below and above the step oscillated laterally on horizontal surfaces for propulsion, whereas the body section in between cantilevered in a vertical plane to bridge the large height increase. As the animal progressed, these three sections traveled down its body, conforming overall body shape to the step. In addition, the snake adjusted the partitioned gait in response to increase in step height and decrease in surface friction, at the cost of reduced speed. As surface friction decreased, body movement below and above the step changed from a continuous lateral undulation with little slip to an intermittent oscillatory movement with much slip, and initial head lift-off became closer to the step. Given these adjustments, body partitioning allowed the snake to be always stable, even when initially cantilevering but before reaching the surface above. Such a partitioned gait may be generally useful for diverse, complex 3-D terrain.
Technology and market perspective for indoor photovoltaic cells

Summary Indoor photovoltaic cells have the potential to power the Internet of Things ecosystem, including distributed and remote sensors, actuators, and communications devices. As the power required to operate these devices continues to decrease, the type and number of nodes that can now be persistently powered by indoor photovoltaic cells are rapidly growing. This will drive significant growth in the demand for indoor photovoltaics, creating a large alternative market for existing and novel photovoltaic technologies. With the re-emergence of interest in indoor photovoltaic cells, we provide an overview of this burgeoning field focusing on the technical challenges that remain to create energy autonomous sensors at viable price points and to overcome the commercial challenges for individual photovoltaic technologies to accelerate their market adoption.
Distributionally robust optimization with correlated data from vector autoregressive processes

Abstract We present a distributionally robust formulation of a stochastic optimization problem for non-i.i.d vector autoregressive data. We use the Wasserstein distance to define robustness in the space of distributions and we show, using duality theory, that the problem is equivalent to a finite convex–concave saddle point problem. The performance of the method is demonstrated on both synthetic and real data.
Locale-agnostic Universal Domain Classification Model in Spoken Language Understanding.

In this paper, we introduce an approach for leveraging available data across multiple locales sharing the same language to 1) improve domain classification model accuracy in Spoken Language Understanding and user experience even if new locales do not have sufficient data and 2) reduce the cost of scaling the domain classifier to a large number of locales. We propose a locale-agnostic universal domain classification model based on selective multi-task learning that learns a joint representation of an utterance over locales with different sets of domains and allows locales to share knowledge selectively depending on the domains. The experimental results demonstrate the effectiveness of our approach on domain classification task in the scenario of multiple locales with imbalanced data and disparate domain sets. The proposed approach outperforms other baselines models especially when classifying locale-specific domains and also low-resourced domains.